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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Gmeb1

Z-value: 0.46

Motif logo

Transcription factors associated with Gmeb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028901.14 Gmeb1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gmeb1mm39_v1_chr4_-_131988832_131988882-0.413.2e-04Click!

Activity profile of Gmeb1 motif

Sorted Z-values of Gmeb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gmeb1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_7163897 3.32 ENSMUST00000020702.11
ENSMUST00000135887.3
insulin-like growth factor binding protein 3
chrX_+_149371219 2.65 ENSMUST00000153221.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_130053120 2.16 ENSMUST00000161640.8
ENSMUST00000161884.2
ENSMUST00000161094.8
argininosuccinate lyase
chr12_+_113104085 1.63 ENSMUST00000200380.5
cysteine rich protein 2
chr11_-_78056347 1.63 ENSMUST00000017530.4
TNF receptor associated factor 4
chr17_+_79922486 1.47 ENSMUST00000225357.2
regulator of microtubule dynamics 2
chr17_+_79922329 1.44 ENSMUST00000040368.3
regulator of microtubule dynamics 2
chr11_-_63813083 1.42 ENSMUST00000094103.4
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr15_-_81283795 1.30 ENSMUST00000023039.15
suppression of tumorigenicity 13
chr17_-_56933872 1.27 ENSMUST00000047226.10
lon peptidase 1, mitochondrial
chr17_+_23898223 1.15 ENSMUST00000024699.4
ENSMUST00000232719.2
claudin 6
chr17_+_23898633 1.14 ENSMUST00000233364.2
claudin 6
chr1_-_91386976 1.00 ENSMUST00000069620.10
period circadian clock 2
chr11_+_53661251 0.97 ENSMUST00000138913.8
ENSMUST00000123376.8
ENSMUST00000019043.13
ENSMUST00000133291.3
interferon regulatory factor 1
chr15_+_81284333 0.92 ENSMUST00000163754.9
ENSMUST00000041609.11
X-prolyl aminopeptidase 3, mitochondrial
chr15_-_81284244 0.88 ENSMUST00000172107.8
ENSMUST00000169204.2
ENSMUST00000163382.2
suppression of tumorigenicity 13
chr14_+_31807760 0.85 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
oxidoreductase NAD-binding domain containing 1
chr11_-_113641980 0.81 ENSMUST00000153453.2
CDC42 effector protein (Rho GTPase binding) 4
chr7_+_30021165 0.81 ENSMUST00000098585.4
RIKEN cDNA E130208F15 gene
chr11_-_86435579 0.79 ENSMUST00000138810.3
ENSMUST00000058286.9
ENSMUST00000154617.8
ribosomal protein S6 kinase, polypeptide 1
chr11_-_83193412 0.77 ENSMUST00000176374.2
peroxisomal biogenesis factor 12
chrX_+_111221031 0.76 ENSMUST00000026599.10
ENSMUST00000113415.2
apolipoprotein O-like
chr15_+_101982208 0.75 ENSMUST00000169681.3
ENSMUST00000229400.2
eukaryotic translation initiation factor 4B
chr4_+_40269563 0.73 ENSMUST00000129758.3
small integral membrane protein 27
chr8_-_25506756 0.71 ENSMUST00000084032.6
ENSMUST00000207132.2
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr15_+_81756671 0.71 ENSMUST00000135198.2
ENSMUST00000157003.8
ENSMUST00000229068.2
aconitase 2, mitochondrial
chr15_-_76191301 0.69 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr9_+_48406706 0.69 ENSMUST00000048824.9
predicted gene 5617
chr8_-_25506916 0.69 ENSMUST00000084035.12
ENSMUST00000208247.3
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr8_+_72914966 0.68 ENSMUST00000003121.9
RAB8A, member RAS oncogene family
chrX_+_7765589 0.67 ENSMUST00000033498.10
translocase of inner mitochondrial membrane 17b
chr8_+_3550533 0.66 ENSMUST00000208306.2
mucolipin 1
chr5_+_113910809 0.57 ENSMUST00000026937.12
ENSMUST00000112311.8
ENSMUST00000112312.8
iron-sulfur cluster assembly enzyme
chr11_+_40624763 0.54 ENSMUST00000127382.2
NudC domain containing 2
chr18_+_36693024 0.52 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr13_-_53627110 0.52 ENSMUST00000021922.10
msh homeobox 2
chr11_-_113642135 0.51 ENSMUST00000106616.2
CDC42 effector protein (Rho GTPase binding) 4
chr4_-_150998857 0.50 ENSMUST00000105675.8
Parkinson disease (autosomal recessive, early onset) 7
chr2_+_26899935 0.50 ENSMUST00000114005.9
ENSMUST00000114004.8
ENSMUST00000114006.8
ENSMUST00000114007.8
ENSMUST00000133807.2
calcium channel flower domain containing 1
chr16_+_20367327 0.49 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr4_-_126096376 0.46 ENSMUST00000106142.8
ENSMUST00000169403.8
ENSMUST00000130334.2
thyroid hormone receptor associated protein 3
chr7_+_46495521 0.45 ENSMUST00000133062.2
lactate dehydrogenase A
chr13_-_69682696 0.44 ENSMUST00000198607.5
terminal nucleotidyltransferase 4A
chr11_+_22940599 0.44 ENSMUST00000020562.5
chaperonin containing Tcp1, subunit 4 (delta)
chr16_+_34842764 0.44 ENSMUST00000061156.10
3-hydroxyacyl-CoA dehydratase 2
chr2_+_75489596 0.44 ENSMUST00000111964.8
ENSMUST00000111962.8
ENSMUST00000111961.8
ENSMUST00000164947.9
ENSMUST00000090792.11
heterogeneous nuclear ribonucleoprotein A3
chr5_-_93354287 0.43 ENSMUST00000144514.3
cyclin I
chr11_+_22940519 0.42 ENSMUST00000173867.8
chaperonin containing Tcp1, subunit 4 (delta)
chr7_+_46495256 0.41 ENSMUST00000048209.16
ENSMUST00000210815.2
ENSMUST00000125862.8
ENSMUST00000210968.2
ENSMUST00000092621.12
ENSMUST00000210467.2
lactate dehydrogenase A
chr6_+_29348068 0.39 ENSMUST00000173216.8
ENSMUST00000173694.5
ENSMUST00000172974.8
ENSMUST00000031779.17
ENSMUST00000090481.14
calumenin
chr2_+_30127692 0.36 ENSMUST00000113654.8
ENSMUST00000095078.3
leucine rich repeat containing 8A VRAC subunit A
chr17_-_46638874 0.36 ENSMUST00000047970.14
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr17_-_46638915 0.34 ENSMUST00000167360.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr19_+_43600738 0.34 ENSMUST00000057178.11
NK2 homeobox 3
chr16_+_36695479 0.33 ENSMUST00000023534.7
ENSMUST00000114812.9
ENSMUST00000134616.8
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr19_+_46064302 0.32 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr7_-_110682204 0.31 ENSMUST00000161051.8
ENSMUST00000160132.8
ENSMUST00000162415.9
eukaryotic translation initiation factor 4, gamma 2
chr11_+_69805005 0.30 ENSMUST00000057884.6
G protein pathway suppressor 2
chr5_-_31448370 0.30 ENSMUST00000041565.11
ENSMUST00000201809.2
intraflagellar transport 172
chr4_-_126096551 0.29 ENSMUST00000080919.12
thyroid hormone receptor associated protein 3
chr4_+_130001349 0.28 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr19_+_46064437 0.26 ENSMUST00000223683.2
nucleolar and coiled-body phosphoprotein 1
chr10_+_80941769 0.26 ENSMUST00000105331.8
mitogen-activated protein kinase kinase 2
chr7_+_101859542 0.25 ENSMUST00000140631.2
ENSMUST00000120879.8
ENSMUST00000146996.8
post-GPI attachment to proteins 2
chr4_+_150999019 0.23 ENSMUST00000135169.8
tumor necrosis factor receptor superfamily, member 9
chr5_+_123153072 0.23 ENSMUST00000051016.5
ENSMUST00000121652.8
ORAI calcium release-activated calcium modulator 1
chr17_+_83658354 0.23 ENSMUST00000096766.12
ENSMUST00000049503.10
ENSMUST00000112363.10
ENSMUST00000234460.2
echinoderm microtubule associated protein like 4
chr4_-_135080437 0.23 ENSMUST00000030613.11
ENSMUST00000131373.8
serine/arginine repetitive matrix 1
chr19_+_46064409 0.22 ENSMUST00000223728.2
ENSMUST00000235620.2
nucleolar and coiled-body phosphoprotein 1
chr18_+_24087725 0.22 ENSMUST00000225682.2
ENSMUST00000060762.6
zinc finger protein 397
chr19_-_44124252 0.22 ENSMUST00000026218.7
CWF19-like 1, cell cycle control (S. pombe)
chr7_+_44146029 0.22 ENSMUST00000205359.2
family with sequence similarity 71, member E1
chr16_-_87229367 0.20 ENSMUST00000232095.2
listerin E3 ubiquitin protein ligase 1
chr5_-_93354348 0.20 ENSMUST00000058550.15
cyclin I
chr16_-_87229485 0.19 ENSMUST00000039449.9
listerin E3 ubiquitin protein ligase 1
chr13_+_49806772 0.19 ENSMUST00000223264.2
ENSMUST00000221142.2
ENSMUST00000222333.2
ENSMUST00000021824.8
nucleolar protein 8
chr10_+_80941749 0.19 ENSMUST00000143517.8
mitogen-activated protein kinase kinase 2
chr4_+_40970906 0.18 ENSMUST00000091614.7
ENSMUST00000030133.15
ENSMUST00000098143.11
nuclear transcription factor, X-box binding 1
chr8_+_3550450 0.18 ENSMUST00000004683.13
ENSMUST00000160338.2
mucolipin 1
chr7_+_44146012 0.16 ENSMUST00000205422.2
family with sequence similarity 71, member E1
chr17_-_29768531 0.16 ENSMUST00000168339.3
ENSMUST00000114683.10
ENSMUST00000234620.2
transmembrane protein 217
chr12_-_31704766 0.16 ENSMUST00000020977.4
dihydrouridine synthase 4-like (S. cerevisiae)
chr3_+_95341698 0.10 ENSMUST00000102749.11
ENSMUST00000090804.12
ENSMUST00000107161.8
ENSMUST00000107160.8
ENSMUST00000015666.17
aryl hydrocarbon receptor nuclear translocator
chr13_+_49806542 0.10 ENSMUST00000222197.2
ENSMUST00000221083.2
ENSMUST00000223467.2
nucleolar protein 8
chr4_+_88692071 0.09 ENSMUST00000177806.2
predicted gene 13290
chrX_-_7765435 0.08 ENSMUST00000115654.8
polyglutamine binding protein 1
chr7_+_101312840 0.08 ENSMUST00000001884.14
ClpB caseinolytic peptidase B
chr9_-_48406564 0.07 ENSMUST00000213276.2
ENSMUST00000170000.4
RNA binding motif protein 7
chr17_-_29768586 0.07 ENSMUST00000234305.2
ENSMUST00000234648.2
ENSMUST00000234979.2
predicted gene, 17657
transmembrane protein 217
chr15_-_79430742 0.06 ENSMUST00000231053.2
ENSMUST00000229431.2
DEAD box helicase 17
chr5_+_93354377 0.06 ENSMUST00000031330.5
RIKEN cDNA 2010109A12 gene
chr11_-_53871121 0.05 ENSMUST00000076493.11
solute carrier family 22 (organic cation transporter), member 21
chr17_-_48145466 0.05 ENSMUST00000066368.13
MyoD family inhibitor
chr7_+_44145987 0.04 ENSMUST00000107927.5
family with sequence similarity 71, member E1
chr7_+_5023375 0.04 ENSMUST00000076251.7
zinc finger protein 865
chr7_-_44145830 0.04 ENSMUST00000118515.9
ENSMUST00000138328.3
ENSMUST00000239015.2
ENSMUST00000118808.9
ER membrane protein complex subunit 10
chr11_-_6576030 0.04 ENSMUST00000000394.14
ENSMUST00000189268.7
ENSMUST00000136682.8
transforming growth factor beta regulated gene 4
chr17_+_84819260 0.04 ENSMUST00000047206.7
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr7_+_101312912 0.03 ENSMUST00000106998.8
ENSMUST00000209579.2
ClpB caseinolytic peptidase B
chr6_-_128401832 0.03 ENSMUST00000203374.3
ENSMUST00000142615.4
ENSMUST00000001559.11
integrin alpha FG-GAP repeat containing 2
chr14_-_31807552 0.03 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
diphthamine biosynthesis 3
chr11_-_97673203 0.03 ENSMUST00000128801.2
ENSMUST00000103146.5
ribosomal protein L23
chr4_+_88698087 0.03 ENSMUST00000179425.2
predicted gene 13272

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:2000843 testosterone secretion(GO:0035936) negative regulation of steroid hormone secretion(GO:2000832) regulation of testosterone secretion(GO:2000843)
0.7 2.2 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.4 1.4 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.3 1.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.3 2.2 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.3 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.0 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 0.5 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.5 GO:1903200 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 1.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.9 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.8 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.8 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 1.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.7 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.9 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 3.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.8 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 2.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.5 2.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 2.2 GO:0032564 dATP binding(GO:0032564)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.7 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.1 0.5 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 2.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import