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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Gzf1

Z-value: 0.45

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Transcription factors associated with Gzf1

Gene Symbol Gene ID Gene Info
Gzf1
ENSMUSG00000027439.10 Gzf1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gzf1mm39_v1_chr2_+_148523118_148523138-0.075.4e-01Click!

Activity profile of Gzf1 motif

Sorted Z-values of Gzf1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gzf1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_65612083 3.70 ENSMUST00000168064.3
Vgll3
vestigial like family member 3
chr4_-_129436465 3.41 ENSMUST00000102597.5
Hdac1
histone deacetylase 1
chr6_-_52181393 3.38 ENSMUST00000048794.7
Hoxa5
homeobox A5
chr16_+_65612394 3.15 ENSMUST00000227997.2
Vgll3
vestigial like family member 3
chr17_+_47905553 2.82 ENSMUST00000182846.3
Ccnd3
cyclin D3
chr4_-_133856025 2.55 ENSMUST00000105879.2
ENSMUST00000030651.9
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
chr4_+_129407374 2.22 ENSMUST00000062356.7
Marcksl1
MARCKS-like 1
chr8_+_23901506 1.65 ENSMUST00000033952.8
Sfrp1
secreted frizzled-related protein 1
chr7_-_30312246 1.62 ENSMUST00000006476.6
Upk1a
uroplakin 1A
chr8_+_79236051 1.53 ENSMUST00000209992.2
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr8_+_79235946 1.51 ENSMUST00000209490.2
ENSMUST00000034111.10
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr13_-_55563028 1.43 ENSMUST00000054146.5
Pfn3
profilin 3
chr9_-_116004265 1.36 ENSMUST00000061101.12
Tgfbr2
transforming growth factor, beta receptor II
chr9_-_116004386 1.28 ENSMUST00000035014.8
Tgfbr2
transforming growth factor, beta receptor II
chr11_-_33113071 1.26 ENSMUST00000093201.13
ENSMUST00000101375.5
ENSMUST00000109354.10
ENSMUST00000075641.10
Npm1
nucleophosmin 1
chr7_-_103778992 1.21 ENSMUST00000053743.6
Ubqln5
ubiquilin 5
chr2_+_162773440 1.09 ENSMUST00000130411.7
ENSMUST00000126163.3
Srsf6
serine and arginine-rich splicing factor 6
chr6_-_51989456 1.03 ENSMUST00000078214.8
ENSMUST00000204778.3
Skap2
src family associated phosphoprotein 2
chr14_+_52860023 0.99 ENSMUST00000103570.2
Trav5-1
T cell receptor alpha variable 5-1
chr8_-_79235505 0.98 ENSMUST00000211719.2
ENSMUST00000049245.10
Rbmxl1
RNA binding motif protein, X-linked like-1
chr17_+_5045178 0.95 ENSMUST00000092723.11
ENSMUST00000232180.2
ENSMUST00000115797.9
Arid1b
AT rich interactive domain 1B (SWI-like)
chr1_+_15875846 0.92 ENSMUST00000188371.7
ENSMUST00000027057.8
Terf1
telomeric repeat binding factor 1
chr12_+_85645801 0.88 ENSMUST00000177587.9
Jdp2
Jun dimerization protein 2
chr14_-_45895515 0.78 ENSMUST00000087320.13
Ddhd1
DDHD domain containing 1
chr14_+_19801333 0.78 ENSMUST00000022340.5
Nid2
nidogen 2
chr17_+_48769383 0.67 ENSMUST00000162132.8
Unc5cl
unc-5 family C-terminal like
chr10_+_82534841 0.63 ENSMUST00000020478.14
Hcfc2
host cell factor C2
chr14_-_45895599 0.59 ENSMUST00000111828.4
ENSMUST00000051310.13
Ddhd1
DDHD domain containing 1
chr8_+_121854566 0.28 ENSMUST00000181609.2
Foxl1
forkhead box L1
chr2_-_93826699 0.06 ENSMUST00000183110.2
Gm27027
predicted gene, 27027

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0060435 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.9 2.6 GO:0002663 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 3.4 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 1.6 GO:2000040 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 1.3 GO:0006407 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.3 0.9 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.3 1.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 0.9 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 2.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.3 GO:0001652 granular component(GO:0001652)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.0 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.6 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.9 2.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 6.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.0 GO:0015293 symporter activity(GO:0015293)
0.0 1.4 GO:0004620 phospholipase activity(GO:0004620)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 3.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing