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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hes5_Hes7

Z-value: 0.69

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Transcription factors associated with Hes5_Hes7

Gene Symbol Gene ID Gene Info
Hes5
ENSMUSG00000048001.8 Hes5
Hes7
ENSMUSG00000023781.3 Hes7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes5mm39_v1_chr4_+_155045372_1550453870.209.8e-02Click!
Hes7mm39_v1_chr11_+_69011230_690112300.191.2e-01Click!

Activity profile of Hes5_Hes7 motif

Sorted Z-values of Hes5_Hes7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes5_Hes7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_25438784 9.06 ENSMUST00000119720.8
ENSMUST00000121438.9
Adam32
a disintegrin and metallopeptidase domain 32
chr3_-_95148909 8.54 ENSMUST00000090815.6
ENSMUST00000107197.2
Gm128
predicted gene 128
chr9_-_121470564 7.36 ENSMUST00000213757.2
ENSMUST00000125075.2
ENSMUST00000077706.10
ENSMUST00000214592.2
Lyzl4
lysozyme-like 4
chrX_+_8137372 6.16 ENSMUST00000127103.8
ENSMUST00000115591.8
Slc38a5
solute carrier family 38, member 5
chrX_+_8137620 6.14 ENSMUST00000033512.11
Slc38a5
solute carrier family 38, member 5
chr19_-_5444413 5.73 ENSMUST00000044527.5
Tsga10ip
testis specific 10 interacting protein
chr9_-_35469818 5.68 ENSMUST00000034612.7
Ddx25
DEAD box helicase 25
chrX_+_8137881 5.64 ENSMUST00000115590.2
Slc38a5
solute carrier family 38, member 5
chr4_+_134195631 4.67 ENSMUST00000030636.11
ENSMUST00000127279.8
ENSMUST00000105867.8
Stmn1
stathmin 1
chr7_+_15795735 4.23 ENSMUST00000209369.2
Zfp541
zinc finger protein 541
chr10_+_97528915 4.13 ENSMUST00000060703.6
Ccer1
coiled-coil glutamate-rich protein 1
chr2_+_155907658 3.84 ENSMUST00000137966.2
Spag4
sperm associated antigen 4
chr17_-_26417982 3.78 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
Pdia2
protein disulfide isomerase associated 2
chr7_+_43910845 3.54 ENSMUST00000124863.4
Gm15517
predicted gene 15517
chr3_+_95466982 3.49 ENSMUST00000090797.11
ENSMUST00000171191.6
ENSMUST00000029754.13
ENSMUST00000107154.4
Hormad1
HORMA domain containing 1
chr11_-_11976237 3.10 ENSMUST00000150972.8
Grb10
growth factor receptor bound protein 10
chr1_-_186875270 3.02 ENSMUST00000184543.2
Spata17
spermatogenesis associated 17
chr9_-_107109108 2.78 ENSMUST00000044532.11
Dock3
dedicator of cyto-kinesis 3
chr11_-_59678462 2.75 ENSMUST00000125307.2
Pld6
phospholipase D family, member 6
chr8_+_120173458 2.72 ENSMUST00000098363.10
Necab2
N-terminal EF-hand calcium binding protein 2
chr4_-_117109074 2.68 ENSMUST00000165128.9
Armh1
armadillo-like helical domain containing 1
chr15_-_95426108 2.57 ENSMUST00000075275.3
Nell2
NEL-like 2
chr6_+_72074545 2.40 ENSMUST00000069994.11
ENSMUST00000114112.4
St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr4_+_154954042 2.39 ENSMUST00000079269.14
ENSMUST00000163732.8
ENSMUST00000080559.13
Mmel1
membrane metallo-endopeptidase-like 1
chr10_-_80223475 2.33 ENSMUST00000105350.3
Mex3d
mex3 RNA binding family member D
chr7_+_119927885 2.24 ENSMUST00000207220.2
ENSMUST00000121265.7
ENSMUST00000076272.5
Abca15
ATP-binding cassette, sub-family A (ABC1), member 15
chr5_+_92534738 2.23 ENSMUST00000128246.8
Art3
ADP-ribosyltransferase 3
chr12_-_72964534 2.13 ENSMUST00000110489.9
4930447C04Rik
RIKEN cDNA 4930447C04 gene
chr18_+_37276556 2.09 ENSMUST00000047479.3
Pcdhac2
protocadherin alpha subfamily C, 2
chr6_+_35154545 1.89 ENSMUST00000170234.2
Nup205
nucleoporin 205
chr2_-_130266162 1.74 ENSMUST00000089581.11
Pced1a
PC-esterase domain containing 1A
chr8_+_61085890 1.62 ENSMUST00000160719.8
Mfap3l
microfibrillar-associated protein 3-like
chr8_+_61085853 1.60 ENSMUST00000161421.2
Mfap3l
microfibrillar-associated protein 3-like
chr8_+_122996308 1.52 ENSMUST00000055537.3
Zfp469
zinc finger protein 469
chrX_+_126301916 1.52 ENSMUST00000051530.4
4921511C20Rik
RIKEN cDNA 4921511C20 gene
chr17_-_3746536 1.51 ENSMUST00000115800.2
Nox3
NADPH oxidase 3
chr6_+_72074718 1.44 ENSMUST00000187007.3
St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr13_-_10410857 1.38 ENSMUST00000187510.7
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr5_-_46014809 1.36 ENSMUST00000190036.7
ENSMUST00000189859.7
ENSMUST00000186633.3
ENSMUST00000016026.14
ENSMUST00000045586.13
ENSMUST00000238522.2
Lcorl
ligand dependent nuclear receptor corepressor-like
chr10_-_67748461 1.30 ENSMUST00000064656.8
Zfp365
zinc finger protein 365
chr9_+_45029080 1.28 ENSMUST00000170998.9
ENSMUST00000093855.4
Scn2b
sodium channel, voltage-gated, type II, beta
chr5_+_28370687 1.28 ENSMUST00000036177.9
En2
engrailed 2
chr1_+_9978863 1.27 ENSMUST00000052843.12
ENSMUST00000171802.8
ENSMUST00000125294.9
ENSMUST00000140948.9
Mcmdc2
minichromosome maintenance domain containing 2
chr9_-_21874802 1.22 ENSMUST00000006397.7
Epor
erythropoietin receptor
chr1_-_161704224 1.21 ENSMUST00000048377.11
Suco
SUN domain containing ossification factor
chr9_-_78350486 1.16 ENSMUST00000070742.14
ENSMUST00000034898.14
Cgas
cyclic GMP-AMP synthase
chr13_+_49806542 1.09 ENSMUST00000222197.2
ENSMUST00000221083.2
ENSMUST00000223467.2
Nol8
nucleolar protein 8
chr12_+_16703383 1.07 ENSMUST00000221596.2
ENSMUST00000111064.3
ENSMUST00000220892.2
Ntsr2
neurotensin receptor 2
chr15_+_81954197 1.05 ENSMUST00000229119.2
ENSMUST00000089178.11
Mei1
meiotic double-stranded break formation protein 1
chr6_+_91134358 1.02 ENSMUST00000155007.2
Hdac11
histone deacetylase 11
chr4_-_149211145 1.00 ENSMUST00000030815.3
Cort
cortistatin
chr11_+_4587733 0.95 ENSMUST00000070257.14
ENSMUST00000109930.3
Ascc2
activating signal cointegrator 1 complex subunit 2
chr11_-_86698484 0.95 ENSMUST00000018569.14
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_-_88531018 0.94 ENSMUST00000165770.9
Zfp423
zinc finger protein 423
chr4_+_155493668 0.89 ENSMUST00000123952.9
ENSMUST00000238423.2
ENSMUST00000238620.2
ENSMUST00000151083.8
Cfap74
cilia and flagella associated protein 74
chr17_+_48623157 0.89 ENSMUST00000049614.13
B430306N03Rik
RIKEN cDNA B430306N03 gene
chr13_+_52000704 0.87 ENSMUST00000021903.3
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_24428351 0.85 ENSMUST00000024931.6
Ntn3
netrin 3
chr19_+_47167259 0.84 ENSMUST00000111808.11
Neurl1a
neuralized E3 ubiquitin protein ligase 1A
chr4_+_117109148 0.83 ENSMUST00000062824.12
Tmem53
transmembrane protein 53
chr11_+_103540391 0.80 ENSMUST00000057870.4
Rprml
reprimo-like
chr4_+_32657105 0.80 ENSMUST00000071642.11
ENSMUST00000178134.2
Mdn1
midasin AAA ATPase 1
chr4_+_117109204 0.80 ENSMUST00000125943.8
ENSMUST00000106434.8
Tmem53
transmembrane protein 53
chr2_+_73102269 0.78 ENSMUST00000090813.6
Sp9
trans-acting transcription factor 9
chr2_+_144441817 0.75 ENSMUST00000028917.7
Dtd1
D-tyrosyl-tRNA deacylase 1
chr1_-_75195127 0.73 ENSMUST00000079464.13
Tuba4a
tubulin, alpha 4A
chr18_+_37453427 0.73 ENSMUST00000078271.4
Pcdhb5
protocadherin beta 5
chr12_+_16703709 0.72 ENSMUST00000221049.2
Ntsr2
neurotensin receptor 2
chr13_+_49806772 0.70 ENSMUST00000223264.2
ENSMUST00000221142.2
ENSMUST00000222333.2
ENSMUST00000021824.8
Nol8
nucleolar protein 8
chr15_-_78739717 0.69 ENSMUST00000044584.6
Lgals2
lectin, galactose-binding, soluble 2
chr2_-_102231208 0.62 ENSMUST00000102573.8
Trim44
tripartite motif-containing 44
chr9_+_75221415 0.62 ENSMUST00000215875.2
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr7_-_65020655 0.62 ENSMUST00000032729.8
Tjp1
tight junction protein 1
chr17_+_36290743 0.62 ENSMUST00000087200.4
Gnl1
guanine nucleotide binding protein-like 1
chr11_+_117545037 0.61 ENSMUST00000026658.13
Tnrc6c
trinucleotide repeat containing 6C
chr7_-_65020955 0.61 ENSMUST00000102592.10
Tjp1
tight junction protein 1
chr11_+_101207021 0.54 ENSMUST00000142640.8
ENSMUST00000019470.14
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr16_-_45544960 0.52 ENSMUST00000096057.5
Tagln3
transgelin 3
chr2_+_91357100 0.44 ENSMUST00000111338.10
Ckap5
cytoskeleton associated protein 5
chr4_-_132484559 0.44 ENSMUST00000030709.9
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr17_+_36172210 0.43 ENSMUST00000074259.15
ENSMUST00000174873.2
Nrm
nurim (nuclear envelope membrane protein)
chr5_-_120610828 0.41 ENSMUST00000052258.14
ENSMUST00000031594.13
Sdsl
serine dehydratase-like
chr1_-_188740023 0.41 ENSMUST00000085678.8
Kctd3
potassium channel tetramerisation domain containing 3
chr4_+_123798690 0.40 ENSMUST00000106202.4
Mycbp
MYC binding protein
chr7_-_130964469 0.39 ENSMUST00000059438.11
2310057M21Rik
RIKEN cDNA 2310057M21 gene
chr2_-_65397850 0.37 ENSMUST00000238483.2
ENSMUST00000100069.9
Scn3a
sodium channel, voltage-gated, type III, alpha
chr1_-_192718064 0.34 ENSMUST00000215093.2
ENSMUST00000195354.6
Syt14
synaptotagmin XIV
chr10_+_79518002 0.32 ENSMUST00000020550.13
Cdc34
cell division cycle 34
chr17_-_36290129 0.32 ENSMUST00000165613.9
ENSMUST00000173872.8
Prr3
proline-rich polypeptide 3
chr11_+_3913970 0.30 ENSMUST00000109985.8
ENSMUST00000020705.5
Pes1
pescadillo ribosomal biogenesis factor 1
chr15_+_32244947 0.28 ENSMUST00000067458.7
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr12_-_56583582 0.28 ENSMUST00000001536.9
Nkx2-1
NK2 homeobox 1
chr3_-_95789338 0.27 ENSMUST00000161994.2
Ciart
circadian associated repressor of transcription
chr15_+_38662158 0.27 ENSMUST00000022904.8
ENSMUST00000228820.2
Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
chr2_-_164032521 0.27 ENSMUST00000051272.8
Wfdc12
WAP four-disulfide core domain 12
chr2_-_65397809 0.25 ENSMUST00000066432.12
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_-_95789505 0.22 ENSMUST00000159863.2
ENSMUST00000159739.8
ENSMUST00000036418.10
ENSMUST00000161866.8
Ciart
circadian associated repressor of transcription
chr10_+_79518138 0.21 ENSMUST00000166603.2
ENSMUST00000219791.2
ENSMUST00000219930.2
ENSMUST00000218964.2
Cdc34
cell division cycle 34
chr5_-_135773047 0.16 ENSMUST00000153399.2
Tmem120a
transmembrane protein 120A
chr8_+_125448867 0.16 ENSMUST00000034463.4
Arv1
ARV1 homolog, fatty acid homeostasis modulator
chr12_+_72807985 0.16 ENSMUST00000021514.10
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr2_-_152306532 0.15 ENSMUST00000099206.3
Defb23
defensin beta 23
chr11_+_59197746 0.14 ENSMUST00000000128.10
ENSMUST00000108783.4
Wnt9a
wingless-type MMTV integration site family, member 9A
chr5_-_99876898 0.13 ENSMUST00000146396.8
ENSMUST00000161148.2
ENSMUST00000161516.2
Rasgef1b
RasGEF domain family, member 1B
chr7_-_98831916 0.10 ENSMUST00000033001.6
Dgat2
diacylglycerol O-acyltransferase 2
chr9_+_55056648 0.10 ENSMUST00000121677.8
Ube2q2
ubiquitin-conjugating enzyme E2Q family member 2
chr17_-_15181491 0.09 ENSMUST00000024657.12
Phf10
PHD finger protein 10
chr13_+_22477363 0.09 ENSMUST00000091735.2
Vmn1r196
vomeronasal 1 receptor 196
chr6_+_116490474 0.08 ENSMUST00000218028.2
ENSMUST00000220134.2
Olfr212
olfactory receptor 212
chr14_-_69945022 0.07 ENSMUST00000118374.8
R3hcc1
R3H domain and coiled-coil containing 1
chr1_+_92500847 0.06 ENSMUST00000074859.3
Olfr1413
olfactory receptor 1413
chr1_-_192717958 0.05 ENSMUST00000016344.9
Syt14
synaptotagmin XIV
chr14_-_69944942 0.05 ENSMUST00000121142.4
R3hcc1
R3H domain and coiled-coil containing 1
chr2_-_155534295 0.03 ENSMUST00000041059.12
Trpc4ap
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr11_-_50216426 0.03 ENSMUST00000179865.8
ENSMUST00000020637.9
Canx
calnexin
chr4_+_123798625 0.02 ENSMUST00000030400.14
Mycbp
MYC binding protein
chr12_+_77285770 0.00 ENSMUST00000062804.8
Fut8
fucosyltransferase 8
chr8_+_13155621 0.00 ENSMUST00000016680.14
ENSMUST00000121426.2
Cul4a
cullin 4A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 1.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.0 17.9 GO:0015816 glycine transport(GO:0015816)
0.9 2.8 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.9 2.7 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.9 3.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.7 2.1 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.7 4.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 1.5 GO:0009629 response to gravity(GO:0009629)
0.4 7.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 1.9 GO:0046684 response to pyrethroid(GO:0046684)
0.3 1.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.3 1.4 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 3.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 1.0 GO:0000237 leptotene(GO:0000237)
0.1 2.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 5.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.6 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.3 GO:1990403 embryonic brain development(GO:1990403)
0.1 2.3 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 3.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 2.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 2.0 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.0 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 1.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.6 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.0 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.8 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 5.7 GO:0033391 chromatoid body(GO:0033391)
0.2 2.1 GO:0000801 central element(GO:0000801)
0.1 1.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 7.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 3.8 GO:0031514 motile cilium(GO:0031514)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 4.9 GO:0043204 perikaryon(GO:0043204)
0.0 3.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.3 17.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.7 2.7 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.6 1.8 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.4 7.4 GO:0003796 lysozyme activity(GO:0003796)
0.3 3.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 3.8 GO:0043495 protein anchor(GO:0043495)
0.2 0.8 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.2 1.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 2.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.4 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.1 6.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 8.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 2.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0031402 voltage-gated sodium channel activity(GO:0005248) sodium ion binding(GO:0031402)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 2.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 7.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis