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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hif1a

Z-value: 1.40

Motif logo

Transcription factors associated with Hif1a

Gene Symbol Gene ID Gene Info
ENSMUSG00000021109.14 Hif1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hif1amm39_v1_chr12_+_73954678_73954789-0.431.5e-04Click!

Activity profile of Hif1a motif

Sorted Z-values of Hif1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hif1a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_84938350 17.02 ENSMUST00000059383.8
ENSMUST00000216889.2
four and a half LIM domains 4
chr4_-_55532453 16.03 ENSMUST00000132746.2
ENSMUST00000107619.3
Kruppel-like factor 4 (gut)
chr18_+_64473091 13.74 ENSMUST00000175965.10
one cut domain, family member 2
chr17_+_28988354 13.28 ENSMUST00000233109.2
ENSMUST00000004986.14
mitogen-activated protein kinase 13
chr17_+_28988271 12.93 ENSMUST00000233984.2
ENSMUST00000233460.2
mitogen-activated protein kinase 13
chr7_+_46495256 11.21 ENSMUST00000048209.16
ENSMUST00000210815.2
ENSMUST00000125862.8
ENSMUST00000210968.2
ENSMUST00000092621.12
ENSMUST00000210467.2
lactate dehydrogenase A
chr7_+_28240262 10.86 ENSMUST00000119180.4
syncollin
chr1_-_75156993 10.39 ENSMUST00000027396.15
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr4_-_43523595 9.98 ENSMUST00000107914.10
tropomyosin 2, beta
chr17_-_43941157 9.52 ENSMUST00000045717.7
ENSMUST00000233077.2
ENSMUST00000168073.9
tudor domain containing 6
chr15_+_80556023 9.38 ENSMUST00000023044.7
family with sequence similarity 83, member F
chr1_+_172309337 9.30 ENSMUST00000127052.8
immunoglobulin superfamily, member 9
chr7_+_142660971 8.66 ENSMUST00000009689.11
potassium voltage-gated channel, subfamily Q, member 1
chr1_+_172309766 8.40 ENSMUST00000135267.8
ENSMUST00000052629.13
ENSMUST00000111235.8
immunoglobulin superfamily, member 9
chr2_+_167922924 7.77 ENSMUST00000052125.7
par-6 family cell polarity regulator beta
chr10_+_43355113 7.54 ENSMUST00000040147.8
BEN domain containing 3
chr7_+_46495521 7.37 ENSMUST00000133062.2
lactate dehydrogenase A
chr2_-_14060774 7.17 ENSMUST00000114753.8
ENSMUST00000091429.12
3-hydroxyacyl-CoA dehydratase 1
chr2_-_14060840 7.08 ENSMUST00000074854.9
3-hydroxyacyl-CoA dehydratase 1
chr11_-_88608958 7.02 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr10_-_80223475 6.81 ENSMUST00000105350.3
mex3 RNA binding family member D
chr12_+_110413523 6.54 ENSMUST00000222276.2
protein phosphatase 2, regulatory subunit B', gamma
chr11_-_88609048 6.45 ENSMUST00000107909.8
musashi RNA-binding protein 2
chr3_-_131196213 6.14 ENSMUST00000197057.2
sphingomyelin synthase 2
chr11_+_61575245 6.09 ENSMUST00000093019.6
family with sequence similarity 83, member G
chr17_+_46991972 5.95 ENSMUST00000002845.8
male enhanced antigen 1
chr14_-_20231871 5.64 ENSMUST00000024011.10
potassium channel, subfamily K, member 5
chr17_+_27276262 5.60 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr19_+_6952580 5.45 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr10_+_43354807 5.41 ENSMUST00000167488.9
BEN domain containing 3
chr5_+_129097133 5.15 ENSMUST00000031383.14
ENSMUST00000111343.2
RAN, member RAS oncogene family
chr7_-_98831916 5.14 ENSMUST00000033001.6
diacylglycerol O-acyltransferase 2
chr11_-_72302520 5.09 ENSMUST00000108500.8
ENSMUST00000050226.7
smoothelin-like 2
chr9_-_95727267 5.06 ENSMUST00000093800.9
plastin 1 (I-isoform)
chr17_+_46991926 5.04 ENSMUST00000233491.2
male enhanced antigen 1
chr2_+_153334710 5.02 ENSMUST00000109783.2
RIKEN cDNA 4930404H24 gene
chr17_+_46991906 4.95 ENSMUST00000233430.2
male enhanced antigen 1
chr1_+_172327812 4.93 ENSMUST00000192460.2
transgelin 2
chr11_+_120839879 4.86 ENSMUST00000154187.8
ENSMUST00000100130.10
ENSMUST00000129473.8
ENSMUST00000168579.8
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr9_-_58220469 4.86 ENSMUST00000061799.10
lysyl oxidase-like 1
chr9_+_107464841 4.81 ENSMUST00000010192.11
interferon-related developmental regulator 2
chr19_+_6952319 4.73 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr15_-_31453708 4.72 ENSMUST00000110408.3
ropporin 1-like
chr1_+_55127110 4.64 ENSMUST00000075242.7
heat shock protein 1 (chaperonin 10)
chr8_+_91635192 4.63 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr15_-_36609208 4.51 ENSMUST00000001809.15
poly(A) binding protein, cytoplasmic 1
chr16_+_70111007 4.47 ENSMUST00000170464.3
glucan (1,4-alpha-), branching enzyme 1
chr9_-_35028100 4.44 ENSMUST00000034537.8
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr10_+_75729237 4.32 ENSMUST00000009236.6
ENSMUST00000217811.2
Der1-like domain family, member 3
chr11_-_102709936 4.30 ENSMUST00000068933.12
gap junction protein, gamma 1
chr6_-_38614155 4.29 ENSMUST00000096030.7
ENSMUST00000201345.2
killer cell lectin-like receptor subfamily G, member 2
chr17_+_46992101 4.20 ENSMUST00000233612.2
male enhanced antigen 1
chr16_+_93885775 4.20 ENSMUST00000072182.9
single-minded family bHLH transcription factor 2
chr19_+_4560500 4.07 ENSMUST00000068004.13
ENSMUST00000224726.3
pyruvate carboxylase
chr19_-_44058175 3.94 ENSMUST00000172041.8
ENSMUST00000071698.13
ENSMUST00000112028.10
ER lipid raft associated 1
chr16_+_70110837 3.92 ENSMUST00000163832.8
glucan (1,4-alpha-), branching enzyme 1
chr15_-_75781387 3.88 ENSMUST00000123712.8
ENSMUST00000141475.2
ENSMUST00000144614.8
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_+_70110975 3.88 ENSMUST00000023393.15
glucan (1,4-alpha-), branching enzyme 1
chr17_+_46991350 3.79 ENSMUST00000232732.2
male enhanced antigen 1
chr3_-_101017594 3.78 ENSMUST00000102694.4
prostaglandin F2 receptor negative regulator
chr11_-_116001037 3.70 ENSMUST00000106441.8
ENSMUST00000021120.6
tripartite motif-containing 47
chr6_-_70769135 3.66 ENSMUST00000066134.6
ribose 5-phosphate isomerase A
chr15_-_102112159 3.64 ENSMUST00000229252.2
ENSMUST00000229770.2
cysteine sulfinic acid decarboxylase
chr8_+_84724130 3.62 ENSMUST00000095228.5
sterile alpha motif domain containing 1
chr19_-_31742427 3.61 ENSMUST00000065067.14
protein kinase, cGMP-dependent, type I
chr11_+_72851989 3.55 ENSMUST00000163326.8
ENSMUST00000108485.9
ENSMUST00000021142.8
ENSMUST00000108486.8
ENSMUST00000108484.8
ATPase, Ca++ transporting, ubiquitous
chr2_-_163261439 3.48 ENSMUST00000046908.10
oxidative stress responsive serine rich 1
chr5_+_108842294 3.46 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr3_+_122039274 3.35 ENSMUST00000178826.8
glutamate-cysteine ligase, modifier subunit
chr4_-_21685781 3.32 ENSMUST00000076206.11
PR domain containing 13
chr5_+_108842088 3.31 ENSMUST00000197255.2
fibroblast growth factor receptor-like 1
chr1_-_55127183 3.30 ENSMUST00000027123.15
heat shock protein 1 (chaperonin)
chr12_+_24701273 3.30 ENSMUST00000020982.7
Kruppel-like factor 11
chr6_-_100264439 3.27 ENSMUST00000101118.4
RING1 and YY1 binding protein
chr15_-_75781138 3.23 ENSMUST00000145764.2
ENSMUST00000116440.9
ENSMUST00000151066.8
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr6_+_108805594 3.22 ENSMUST00000089162.5
ER degradation enhancer, mannosidase alpha-like 1
chr15_-_36609812 3.21 ENSMUST00000226496.2
poly(A) binding protein, cytoplasmic 1
chr3_-_75864195 3.19 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr19_-_44057800 3.14 ENSMUST00000170801.8
ER lipid raft associated 1
chr1_+_74811045 3.09 ENSMUST00000006716.8
wingless-type MMTV integration site family, member 6
chr15_-_75781168 3.09 ENSMUST00000089680.10
ENSMUST00000141268.8
ENSMUST00000023235.13
ENSMUST00000109972.9
ENSMUST00000089681.12
ENSMUST00000109975.10
ENSMUST00000154584.9
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr9_+_107446310 3.05 ENSMUST00000010191.13
ENSMUST00000193747.2
hyaluronoglucosaminidase 2
chr6_+_88701810 3.00 ENSMUST00000089449.5
monoglyceride lipase
chr5_+_108842125 2.93 ENSMUST00000112560.8
fibroblast growth factor receptor-like 1
chr5_+_77414031 2.88 ENSMUST00000113449.2
RE1-silencing transcription factor
chr10_+_95776543 2.86 ENSMUST00000053484.8
early endosome antigen 1
chr7_-_68398989 2.84 ENSMUST00000048068.15
arrestin domain containing 4
chr1_-_36722195 2.82 ENSMUST00000170295.8
ENSMUST00000114981.3
family with sequence similarity 178, member B
chr7_-_68398917 2.81 ENSMUST00000118110.3
arrestin domain containing 4
chr12_+_32870334 2.80 ENSMUST00000020886.9
nicotinamide phosphoribosyltransferase
chr10_+_17598961 2.79 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_+_10583629 2.66 ENSMUST00000115524.8
ENSMUST00000008179.7
ENSMUST00000156321.2
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr1_+_78286946 2.54 ENSMUST00000036172.10
sphingosine-1-phosphate phosphatase 2
chr19_+_25587896 2.54 ENSMUST00000048935.6
doublesex and mab-3 related transcription factor 3
chr3_+_122039206 2.54 ENSMUST00000029769.14
glutamate-cysteine ligase, modifier subunit
chr8_-_123278054 2.53 ENSMUST00000156333.9
ENSMUST00000067252.14
piezo-type mechanosensitive ion channel component 1
chr2_+_68691778 2.39 ENSMUST00000028426.9
ceramide synthase 6
chr8_+_34006758 2.32 ENSMUST00000149399.8
testis expressed gene 15
chr16_+_70110944 2.29 ENSMUST00000171132.8
glucan (1,4-alpha-), branching enzyme 1
chr19_-_44058129 2.26 ENSMUST00000169092.2
ER lipid raft associated 1
chr14_-_21102487 2.24 ENSMUST00000154460.8
ENSMUST00000130291.8
adaptor-related protein complex 3, mu 1 subunit
chr6_-_86503178 2.21 ENSMUST00000053015.7
poly(rC) binding protein 1
chr4_-_129494435 2.20 ENSMUST00000102593.11
eukaryotic translation initiation factor 3, subunit I
chr8_+_34222058 2.18 ENSMUST00000167264.8
ENSMUST00000187392.7
general transcription factor II E, polypeptide 2 (beta subunit)
chr11_+_60428788 2.12 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr4_+_152410291 2.12 ENSMUST00000103191.11
ENSMUST00000139685.8
ENSMUST00000188151.2
ribosomal protein L22
chr8_+_34221861 2.07 ENSMUST00000170705.8
general transcription factor II E, polypeptide 2 (beta subunit)
chr9_+_108225026 2.07 ENSMUST00000035237.12
ENSMUST00000194959.6
ubiquitin specific peptidase 4 (proto-oncogene)
chr8_+_34222266 1.98 ENSMUST00000190675.2
ENSMUST00000171010.8
general transcription factor II E, polypeptide 2 (beta subunit)
chr2_+_74593324 1.98 ENSMUST00000047793.6
homeobox D1
chr1_+_120530134 1.97 ENSMUST00000079721.9
engrailed 1
chr4_-_62438122 1.97 ENSMUST00000107444.8
ENSMUST00000030090.4
aminolevulinate, delta-, dehydratase
chr7_+_98138904 1.92 ENSMUST00000205956.2
leucine rich repeat containing 32
chr10_+_80100812 1.84 ENSMUST00000105362.8
ENSMUST00000105361.10
DAZ associated protein 1
chr13_-_53135064 1.82 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr12_+_104998895 1.80 ENSMUST00000223244.2
ENSMUST00000021522.5
glutaredoxin 5
chr5_-_148988413 1.78 ENSMUST00000093196.11
high mobility group box 1
chr10_+_84938452 1.78 ENSMUST00000095383.6
transmembrane protein 263
chr2_-_27317004 1.74 ENSMUST00000056176.8
vav 2 oncogene
chr4_-_43045685 1.73 ENSMUST00000107956.8
ENSMUST00000107957.8
family with sequence similarity 214, member B
chr14_+_21102642 1.73 ENSMUST00000045376.11
adenosine kinase
chr4_-_118148471 1.61 ENSMUST00000222620.2
protein tyrosine phosphatase, receptor type, F
chr14_-_30740946 1.61 ENSMUST00000228341.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr17_-_46991709 1.61 ENSMUST00000233524.2
ENSMUST00000233733.2
ENSMUST00000071841.7
ENSMUST00000165007.9
kelch domain containing 3
chr5_-_144902598 1.58 ENSMUST00000110677.8
ENSMUST00000085684.11
ENSMUST00000100461.7
SMAD specific E3 ubiquitin protein ligase 1
chr7_-_136915602 1.53 ENSMUST00000210774.2
early B cell factor 3
chr14_-_30741012 1.52 ENSMUST00000037739.8
guanine nucleotide binding protein-like 3 (nucleolar)
chr4_-_43046196 1.52 ENSMUST00000036462.12
family with sequence similarity 214, member B
chr4_+_116734573 1.52 ENSMUST00000044823.4
zinc finger SWIM-type containing 5
chr5_+_135197228 1.51 ENSMUST00000111187.10
ENSMUST00000111188.5
ENSMUST00000202606.3
B cell CLL/lymphoma 7B
chr14_+_21102662 1.45 ENSMUST00000223915.2
adenosine kinase
chr17_-_23896394 1.45 ENSMUST00000233428.2
ENSMUST00000233814.2
ENSMUST00000167059.9
ENSMUST00000024698.10
tumor necrosis factor receptor superfamily, member 12a
chr15_+_85942928 1.41 ENSMUST00000138134.8
GRAM domain containing 4
chr8_+_105318067 1.40 ENSMUST00000059588.8
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr4_-_129494378 1.40 ENSMUST00000135055.8
eukaryotic translation initiation factor 3, subunit I
chr17_-_26314438 1.39 ENSMUST00000236547.2
NME/NM23 nucleoside diphosphate kinase 4
chr17_-_26314461 1.37 ENSMUST00000236128.2
ENSMUST00000025007.7
NME/NM23 nucleoside diphosphate kinase 4
chr2_+_155359868 1.35 ENSMUST00000029135.15
ENSMUST00000065973.9
acyl-CoA synthetase short-chain family member 2
chr13_+_81805941 1.33 ENSMUST00000049055.8
LysM, putative peptidoglycan-binding, domain containing 3
chr7_+_98138490 1.32 ENSMUST00000205937.2
leucine rich repeat containing 32
chr6_+_88701394 1.32 ENSMUST00000113585.9
monoglyceride lipase
chr19_-_44994824 1.26 ENSMUST00000097715.4
mitochondrial ribosomal protein L43
chr2_+_27405169 1.25 ENSMUST00000113952.10
WD repeat domain 5
chr11_-_120238917 1.25 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr14_-_31552335 1.24 ENSMUST00000228037.2
ankyrin repeat domain 28
chr13_+_81805782 1.23 ENSMUST00000224300.2
ENSMUST00000224592.2
LysM, putative peptidoglycan-binding, domain containing 3
chr6_-_83433357 1.23 ENSMUST00000186548.7
tet methylcytosine dioxygenase 3
chr13_-_30168374 1.20 ENSMUST00000221536.2
ENSMUST00000222730.2
E2F transcription factor 3
chr16_-_10994135 1.20 ENSMUST00000037633.16
zinc finger CCCH type containing 7 A
chr10_+_80100868 1.18 ENSMUST00000092305.6
DAZ associated protein 1
chr2_+_127967951 1.16 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
BCL2-like 11 (apoptosis facilitator)
chr11_-_95956176 1.13 ENSMUST00000100528.5
ubiquitin-conjugating enzyme E2Z
chr3_-_58599812 1.12 ENSMUST00000070368.8
siah E3 ubiquitin protein ligase 2
chr11_+_102080446 1.11 ENSMUST00000070334.10
glucose 6 phosphatase, catalytic, 3
chr15_-_57755753 1.11 ENSMUST00000022993.7
Der1-like domain family, member 1
chr1_-_180083859 1.10 ENSMUST00000111108.10
presenilin 2
chr12_-_40087393 1.10 ENSMUST00000146905.2
ADP-ribosylation factor-like 4A
chr15_+_80862074 1.09 ENSMUST00000229727.2
small G protein signaling modulator 3
chr8_-_70426910 1.08 ENSMUST00000116463.4
GATA zinc finger domain containing 2A
chr6_+_88701578 1.07 ENSMUST00000150180.4
ENSMUST00000163271.8
monoglyceride lipase
chr11_-_102710490 1.07 ENSMUST00000092567.11
gap junction protein, gamma 1
chr9_-_110483210 1.05 ENSMUST00000196488.5
ENSMUST00000133191.8
ENSMUST00000167320.8
neurobeachin-like 2
chr13_-_112788829 1.04 ENSMUST00000075748.7
DEAD box helicase 4
chr2_+_179761093 1.03 ENSMUST00000040668.9
oxysterol binding protein-like 2
chr9_-_57168777 1.02 ENSMUST00000217657.2
RIKEN cDNA 1700017B05 gene
chr11_-_120239301 1.02 ENSMUST00000062147.14
ENSMUST00000128055.2
actin, gamma, cytoplasmic 1
chr14_+_16182428 1.02 ENSMUST00000170104.3
predicted gene 3411
chr5_-_123662175 1.00 ENSMUST00000200247.5
ENSMUST00000111586.8
ENSMUST00000031385.7
ENSMUST00000145152.8
ENSMUST00000111587.10
diablo, IAP-binding mitochondrial protein
chr5_+_33815466 0.98 ENSMUST00000074849.13
ENSMUST00000079534.11
ENSMUST00000201633.2
transforming, acidic coiled-coil containing protein 3
chr7_-_121666486 0.95 ENSMUST00000033159.4
glutamyl-tRNA synthetase 2, mitochondrial
chr11_-_120239339 0.93 ENSMUST00000071555.13
actin, gamma, cytoplasmic 1
chr8_+_111821262 0.90 ENSMUST00000135302.8
ENSMUST00000039333.10
pyruvate dehydrogenase phosphatase regulatory subunit
chr11_-_72380730 0.88 ENSMUST00000045303.10
spinster homolog 2
chr6_+_88701470 0.87 ENSMUST00000113581.8
monoglyceride lipase
chr14_+_121148625 0.87 ENSMUST00000032898.9
importin 5
chr1_-_161078723 0.86 ENSMUST00000051925.5
ENSMUST00000071718.12
peroxiredoxin 6
chr2_+_162773440 0.83 ENSMUST00000130411.7
ENSMUST00000126163.3
serine and arginine-rich splicing factor 6
chr5_+_45650821 0.82 ENSMUST00000198534.2
leucine aminopeptidase 3
chr13_-_72111832 0.77 ENSMUST00000077337.9
Iroquois homeobox 1
chr19_+_44994905 0.77 ENSMUST00000026227.3
twinkle mtDNA helicase
chr5_-_135280063 0.76 ENSMUST00000062572.3
frizzled class receptor 9
chr4_-_34882917 0.74 ENSMUST00000098163.9
ENSMUST00000047950.6
zinc finger protein 292
chr4_+_129494463 0.73 ENSMUST00000102591.10
ENSMUST00000181579.8
ENSMUST00000173758.8
transmembrane protein 234
chr11_-_88608920 0.72 ENSMUST00000092794.12
musashi RNA-binding protein 2
chr7_+_99808452 0.70 ENSMUST00000032967.4
lipoyl(octanoyl) transferase 2 (putative)
chr4_+_101276893 0.70 ENSMUST00000131397.2
ENSMUST00000133055.8
adenylate kinase 4
chr5_+_135093056 0.68 ENSMUST00000071263.7
DnaJ heat shock protein family (Hsp40) member C30
chr4_-_57300361 0.67 ENSMUST00000153926.8
protein tyrosine phosphatase, non-receptor type 3
chr2_+_68691902 0.66 ENSMUST00000176018.2
ceramide synthase 6
chr8_-_46605196 0.64 ENSMUST00000110378.9
sorting nexin 25
chr13_-_112788890 0.64 ENSMUST00000099166.10
DEAD box helicase 4
chr2_+_155360015 0.62 ENSMUST00000103142.12
acyl-CoA synthetase short-chain family member 2
chr3_+_152101698 0.62 ENSMUST00000200570.5
zinc finger, ZZ domain containing 3
chr12_+_110413677 0.61 ENSMUST00000220509.2
protein phosphatase 2, regulatory subunit B', gamma
chr16_+_32698470 0.61 ENSMUST00000232272.2
forty-two-three domain containing 1
chr18_-_3337679 0.60 ENSMUST00000150235.8
ENSMUST00000154470.8
cAMP responsive element modulator
chr9_+_70450130 0.58 ENSMUST00000049263.9
SAFB-like, transcription modulator
chr7_+_3706992 0.57 ENSMUST00000006496.15
ENSMUST00000108623.8
ENSMUST00000139818.2
ENSMUST00000108625.8
ribosomal protein S9
chr11_+_117006020 0.57 ENSMUST00000103026.10
ENSMUST00000090433.6
SEC14-like lipid binding 1
chr10_-_13068900 0.57 ENSMUST00000019950.6
LTV1 ribosome biogenesis factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 16.0 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
2.9 8.7 GO:0072347 response to anesthetic(GO:0072347)
1.9 18.6 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.7 5.1 GO:0034201 response to oleic acid(GO:0034201)
1.6 13.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.5 10.4 GO:0015886 heme transport(GO:0015886)
1.3 5.4 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.3 5.1 GO:1902896 terminal web assembly(GO:1902896)
1.1 7.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.1 3.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.1 3.2 GO:0006175 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175)
1.0 5.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 5.6 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.9 3.7 GO:0006014 D-ribose metabolic process(GO:0006014)
0.9 2.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.8 9.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.8 4.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 3.0 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 3.6 GO:0042412 taurine biosynthetic process(GO:0042412)
0.7 3.6 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.7 2.9 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.7 2.8 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.7 13.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.7 2.0 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.7 5.9 GO:0051409 response to nitrosative stress(GO:0051409)
0.6 6.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 1.8 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.6 5.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 14.3 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.5 1.6 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.5 2.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 9.7 GO:0060539 diaphragm development(GO:0060539)
0.4 0.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.4 1.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.4 4.9 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.4 4.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.4 2.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 3.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684) positive regulation of tooth mineralization(GO:0070172)
0.3 1.8 GO:0009249 protein lipoylation(GO:0009249)
0.3 1.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3 5.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 2.0 GO:0061743 motor learning(GO:0061743)
0.3 1.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3 0.8 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 1.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 1.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 4.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 3.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 10.2 GO:0009299 mRNA transcription(GO:0009299)
0.2 24.5 GO:0006970 response to osmotic stress(GO:0006970)
0.2 1.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 2.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 2.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 1.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 14.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 3.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 8.3 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.2 0.5 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.2 2.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 5.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 1.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.8 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.2 3.8 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 2.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 1.0 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 2.5 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 4.3 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 2.7 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 17.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.0 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 4.7 GO:0048240 sperm capacitation(GO:0048240)
0.1 3.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.4 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 1.1 GO:0043589 skin morphogenesis(GO:0043589)
0.1 2.5 GO:0030539 male genitalia development(GO:0030539)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.6 GO:0034214 protein hexamerization(GO:0034214)
0.1 4.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 3.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 4.2 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 6.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 7.8 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 3.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 13.0 GO:0048864 stem cell development(GO:0048864)
0.0 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 28.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 2.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 3.2 GO:0045214 sarcomere organization(GO:0045214)
0.0 5.3 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 4.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 2.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 8.1 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 2.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 3.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.1 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
2.0 5.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.7 5.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.5 10.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.8 5.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.7 10.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 18.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 2.9 GO:0044308 axonal spine(GO:0044308)
0.6 5.1 GO:1990357 terminal web(GO:1990357)
0.6 11.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4 17.7 GO:0060077 inhibitory synapse(GO:0060077)
0.3 3.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 2.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 7.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 16.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 7.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 9.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 5.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 16.7 GO:0005844 polysome(GO:0005844)
0.2 7.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 5.8 GO:0043196 varicosity(GO:0043196)
0.2 5.4 GO:0005922 connexon complex(GO:0005922)
0.2 13.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 27.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 10.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 3.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 3.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.2 GO:0001940 male pronucleus(GO:0001940)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.2 GO:0043034 costamere(GO:0043034)
0.1 1.6 GO:0005921 gap junction(GO:0005921)
0.1 0.6 GO:0034448 EGO complex(GO:0034448)
0.1 1.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.0 GO:0005839 proteasome core complex(GO:0005839)
0.1 9.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 8.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 7.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 9.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 4.7 GO:0031514 motile cilium(GO:0031514)
0.0 9.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 4.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.4 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
3.6 14.6 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
3.2 9.7 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
3.2 16.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.0 5.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.7 10.4 GO:0015232 heme transporter activity(GO:0015232)
1.7 18.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.4 5.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.3 5.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.3 5.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
1.2 8.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.2 13.0 GO:0000182 rDNA binding(GO:0000182)
1.1 3.2 GO:0004001 adenosine kinase activity(GO:0004001)
1.0 6.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.0 4.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.0 24.5 GO:0004707 MAP kinase activity(GO:0004707)
0.9 2.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.8 3.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.7 21.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.6 5.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.6 2.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.6 4.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.6 3.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.6 1.8 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.6 2.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 4.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 3.6 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.4 17.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 2.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 10.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 1.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 2.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 3.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 5.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 2.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 1.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 3.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 2.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 2.8 GO:1901612 cardiolipin binding(GO:1901612)
0.3 5.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 3.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 2.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 4.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 10.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 2.8 GO:0050693 LBD domain binding(GO:0050693)
0.2 3.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 6.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 10.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 3.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 10.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 2.2 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 7.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.5 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.9 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 4.6 GO:0051087 chaperone binding(GO:0051087)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 4.8 GO:0004386 helicase activity(GO:0004386)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 9.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 3.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 10.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 5.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 20.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 14.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 8.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 3.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 3.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 5.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 24.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
1.0 24.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.7 16.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 5.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 7.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 3.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 8.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 11.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 3.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 8.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 5.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 3.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 5.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 10.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 7.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 6.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 8.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 10.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 17.7 REACTOME TRANSLATION Genes involved in Translation
0.1 4.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 2.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 4.9 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions