Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Hlf

Z-value: 1.41

Motif logo

Transcription factors associated with Hlf

Gene Symbol Gene ID Gene Info
ENSMUSG00000003949.17 Hlf

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hlfmm39_v1_chr11_-_90281721_90281753-0.113.5e-01Click!

Activity profile of Hlf motif

Sorted Z-values of Hlf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlf

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr3_+_59939175 13.45 ENSMUST00000029325.5
arylacetamide deacetylase
chr7_+_26534730 12.12 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr7_+_26006594 11.89 ENSMUST00000098657.5
cytochrome P450, family 2, subfamily a, polypeptide 4
chr19_+_31846154 10.69 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
APOBEC1 complementation factor
chr6_-_115569504 10.31 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr16_+_22738987 9.86 ENSMUST00000023587.12
fetuin beta
chr9_-_78254422 9.70 ENSMUST00000034902.12
glutathione S-transferase, alpha 2 (Yc2)
chr8_+_46924074 9.46 ENSMUST00000034046.13
ENSMUST00000211644.2
acyl-CoA synthetase long-chain family member 1
chr15_-_3612078 9.00 ENSMUST00000161770.2
growth hormone receptor
chr9_-_78254443 8.80 ENSMUST00000129247.2
glutathione S-transferase, alpha 2 (Yc2)
chr12_-_81014755 8.31 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr13_+_4624074 8.10 ENSMUST00000021628.4
aldo-keto reductase family 1, member C21
chr16_+_37400500 8.09 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr16_+_37400590 7.95 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr7_-_30643444 7.81 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr7_+_123061535 7.36 ENSMUST00000098056.6
aquaporin 8
chr16_-_22847808 7.34 ENSMUST00000115349.9
kininogen 2
chr10_+_21253190 7.22 ENSMUST00000042699.14
aldehyde dehydrogenase 8 family, member A1
chr7_+_123061497 7.22 ENSMUST00000033023.10
aquaporin 8
chr7_+_25872836 7.07 ENSMUST00000082214.5
cytochrome P450, family 2, subfamily b, polypeptide 9
chr7_-_46392403 7.03 ENSMUST00000128088.4
serum amyloid A 1
chr19_-_34724689 7.01 ENSMUST00000009522.4
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr10_+_23727325 6.97 ENSMUST00000020190.8
vanin 3
chr11_-_77784922 6.84 ENSMUST00000017597.5
pipecolic acid oxidase
chr16_-_22847760 6.76 ENSMUST00000039338.13
kininogen 2
chr15_+_89218601 6.60 ENSMUST00000023282.9
myo-inositol oxygenase
chr6_+_17463748 6.54 ENSMUST00000115443.8
met proto-oncogene
chr16_+_22769822 6.46 ENSMUST00000023590.9
histidine-rich glycoprotein
chr8_+_86219191 6.44 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr9_+_78197205 6.40 ENSMUST00000119823.8
ENSMUST00000121273.2
glutathione S-transferase alpha 5
chr14_+_40827317 6.38 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr16_+_22739191 6.34 ENSMUST00000116625.10
fetuin beta
chr4_-_49408040 6.32 ENSMUST00000081541.9
acyl-coenzyme A amino acid N-acyltransferase 2
chr16_-_22847829 6.31 ENSMUST00000100046.9
kininogen 2
chr12_-_104831266 5.86 ENSMUST00000109937.9
calmin
chr4_+_56743407 5.85 ENSMUST00000095079.6
actin-like 7a
chr9_+_78137927 5.83 ENSMUST00000098537.4
glutathione S-transferase, alpha 1 (Ya)
chr6_+_121815473 5.82 ENSMUST00000032228.9
murinoglobulin 1
chr12_-_81014849 5.81 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_+_22739028 5.81 ENSMUST00000232097.2
fetuin beta
chr16_-_38253507 5.64 ENSMUST00000002926.8
phospholipase A1 member A
chr10_-_125225298 5.35 ENSMUST00000210780.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr9_+_78164402 5.27 ENSMUST00000217203.2
predicted gene 3776
chr5_+_88127290 5.23 ENSMUST00000008051.5
calcium binding protein, spermatid specific 1
chr8_-_93956143 5.16 ENSMUST00000176282.2
ENSMUST00000034173.14
carboxylesterase 1E
chr4_-_128154709 5.03 ENSMUST00000053830.5
high-mobility group box 4
chr7_+_119773070 5.00 ENSMUST00000033201.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr15_-_76191301 4.97 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr15_+_25910510 4.88 ENSMUST00000228600.2
reticulophagy regulator 1
chr19_-_7779943 4.84 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr16_-_22848153 4.82 ENSMUST00000232459.2
kininogen 2
chr15_+_54274151 4.78 ENSMUST00000036737.4
collectin sub-family member 10
chr16_+_22769844 4.63 ENSMUST00000232422.2
histidine-rich glycoprotein
chr4_-_115910577 4.55 ENSMUST00000165493.8
NOL1/NOP2/Sun domain family, member 4
chr7_-_26638802 4.52 ENSMUST00000170227.3
cytochrome P450, family 2, subfamily a, polypeptide 22
chr6_+_17463819 4.51 ENSMUST00000140070.8
met proto-oncogene
chr5_-_87074380 4.47 ENSMUST00000031183.3
UDP glucuronosyltransferase 2 family, polypeptide B1
chr11_+_115353290 4.28 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr10_+_100428212 4.20 ENSMUST00000187119.7
ENSMUST00000188736.7
ENSMUST00000191336.7
RIKEN cDNA 1700017N19 gene
chr4_-_25242858 4.13 ENSMUST00000029922.14
ENSMUST00000108204.2
four and a half LIM domains 5
chr19_-_7780025 4.11 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr7_-_126873219 3.88 ENSMUST00000082428.6
selenophosphate synthetase 2
chr16_-_97564910 3.87 ENSMUST00000019386.10
receptor-interacting serine-threonine kinase 4
chr9_-_107546166 3.86 ENSMUST00000177567.8
solute carrier family 38, member 3
chr3_-_142101339 3.83 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr12_-_104831335 3.81 ENSMUST00000109936.3
calmin
chr9_+_32283779 3.80 ENSMUST00000047334.10
potassium inwardly-rectifying channel, subfamily J, member 1
chr8_-_79975199 3.80 ENSMUST00000034109.6
RIKEN cDNA 1700011L22 gene
chrX_+_137986975 3.77 ENSMUST00000033625.2
RIKEN cDNA 4930513O06 gene
chr1_-_140111018 3.77 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr10_+_100428246 3.76 ENSMUST00000041162.13
ENSMUST00000190386.7
ENSMUST00000190708.7
RIKEN cDNA 1700017N19 gene
chr17_+_33651864 3.75 ENSMUST00000174088.3
actin-like 9
chr9_-_107546195 3.72 ENSMUST00000192990.6
solute carrier family 38, member 3
chr8_-_118398264 3.72 ENSMUST00000037955.14
short chain dehydrogenase/reductase family 42E, member 1
chr3_+_138148846 3.69 ENSMUST00000005964.7
alcohol dehydrogenase 5 (class III), chi polypeptide
chr6_-_142418801 3.68 ENSMUST00000032371.8
glycogen synthase 2
chr17_-_32255287 3.63 ENSMUST00000238192.2
heat shock transcription factor 2 binding protein
chr8_+_95055829 3.62 ENSMUST00000034218.5
ENSMUST00000212134.2
solute carrier family 12, member 3
chr1_-_71692320 3.59 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr1_-_140111138 3.57 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr11_+_70506674 3.53 ENSMUST00000180052.8
RIKEN cDNA 4930544D05 gene
chr3_-_129126362 3.53 ENSMUST00000029658.14
glutamyl aminopeptidase
chr7_+_43361930 3.49 ENSMUST00000066834.8
kallikrein related-peptidase 13
chr9_-_71070506 3.49 ENSMUST00000074465.9
aquaporin 9
chr11_+_118913788 3.45 ENSMUST00000026662.8
chromobox 2
chr9_-_106438798 3.42 ENSMUST00010126732.2
ENSMUST00010126033.2
ENSMUST00010181659.1
ENSMUST00010126065.2
ENSMUST00010126032.3
ENSMUST00000062917.16
IQ motif containing F3
IQ motif containing F3
chr14_-_61495832 3.40 ENSMUST00000121148.8
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr2_+_124994425 3.38 ENSMUST00000110494.9
ENSMUST00000110495.3
ENSMUST00000028630.9
solute carrier family 12, member 1
chr7_+_25760922 3.35 ENSMUST00000005669.9
cytochrome P450, family 2, subfamily b, polypeptide 13
chr8_-_34419826 3.34 ENSMUST00000033995.14
ENSMUST00000033994.15
ENSMUST00000191473.7
ENSMUST00000053251.12
RNA binding protein gene with multiple splicing
chr11_+_70506716 3.33 ENSMUST00000144960.2
RIKEN cDNA 4930544D05 gene
chr1_-_171173198 3.31 ENSMUST00000111295.8
ENSMUST00000148339.2
ENSMUST00000111289.8
nitrilase 1
chr6_+_30512285 3.26 ENSMUST00000031798.14
serine-rich single-pass membrane protein 1
chr6_+_124785621 3.25 ENSMUST00000047760.10
splA/ryanodine receptor domain and SOCS box containing 2
chr14_-_61495934 3.24 ENSMUST00000077954.13
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr14_+_79086492 3.22 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr6_+_24597724 3.22 ENSMUST00000031694.8
leiomodin 2 (cardiac)
chr9_+_107957640 3.22 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_107957621 3.20 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr4_-_115911053 3.20 ENSMUST00000030475.3
NOL1/NOP2/Sun domain family, member 4
chr2_+_89808124 3.19 ENSMUST00000061830.2
olfactory receptor 1260
chr6_+_126830102 3.17 ENSMUST00000202878.4
ENSMUST00000202574.2
A kinase (PRKA) anchor protein 3
chr7_+_67297152 3.16 ENSMUST00000032774.16
ENSMUST00000107471.8
tetratricopeptide repeat domain 23
chr8_-_13612397 3.07 ENSMUST00000187391.7
ENSMUST00000134023.9
ENSMUST00000151400.10
RIKEN cDNA 1700029H14 gene
chr11_+_67128843 3.07 ENSMUST00000018632.11
myosin, heavy polypeptide 4, skeletal muscle
chr6_+_124785834 3.02 ENSMUST00000143040.8
ENSMUST00000052727.5
ENSMUST00000130160.2
splA/ryanodine receptor domain and SOCS box containing 2
chr10_-_99595498 3.01 ENSMUST00000056085.6
citrate synthase like
chr6_+_41661356 3.00 ENSMUST00000031900.6
LLLL and CFNLAS motif containing 1
chr2_+_69500444 2.99 ENSMUST00000100050.4
kelch-like 41
chr13_+_4283729 2.98 ENSMUST00000081326.7
aldo-keto reductase family 1, member C19
chr1_-_171173168 2.97 ENSMUST00000156856.8
ENSMUST00000111296.8
nitrilase 1
chr2_+_144665576 2.95 ENSMUST00000028918.4
SCP2 sterol-binding domain containing 1
chr7_+_43491689 2.93 ENSMUST00000048444.7
kallikrein related-peptidase 5
chr5_-_5564730 2.84 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr5_-_87240405 2.80 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr6_+_126830050 2.80 ENSMUST00000095440.9
A kinase (PRKA) anchor protein 3
chr1_+_175526152 2.78 ENSMUST00000094288.10
ENSMUST00000171939.8
WD repeat domain 64
chr2_-_90735171 2.77 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr4_-_86476502 2.76 ENSMUST00000030216.6
stabilizer of axonemal microtubules 1
chr15_-_58953838 2.75 ENSMUST00000080371.8
MTSS I-BAR domain containing 1
chr17_+_79922329 2.75 ENSMUST00000040368.3
regulator of microtubule dynamics 2
chr13_-_32960379 2.73 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr6_+_90442269 2.72 ENSMUST00000113530.4
Kruppel-like factor 15
chr3_-_113368407 2.70 ENSMUST00000106540.8
amylase 1, salivary
chr10_-_95678748 2.64 ENSMUST00000210336.2
predicted gene, 33543
chr7_+_46401214 2.61 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr15_+_57849269 2.58 ENSMUST00000050374.3
family with sequence similarity 83, member A
chr14_-_54647647 2.57 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr3_+_87814147 2.57 ENSMUST00000159492.8
heparin binding growth factor
chr19_+_5385672 2.55 ENSMUST00000043380.5
cation channel, sperm associated 1
chr14_-_54648057 2.54 ENSMUST00000200545.2
ENSMUST00000227967.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr16_-_64422716 2.54 ENSMUST00000209382.3
casein kinase 2, alpha prime interacting protein
chr15_+_44482944 2.51 ENSMUST00000022964.9
estrogen receptor-binding fragment-associated gene 9
chr2_+_148677060 2.51 ENSMUST00000028935.4
cystatin 9
chr5_-_92475927 2.50 ENSMUST00000113093.5
chemokine (C-X-C motif) ligand 9
chr16_-_56652241 2.49 ENSMUST00000135672.2
transmembrane protein 45a
chr13_+_23715220 2.49 ENSMUST00000102972.6
H4 clustered histone 8
chr2_+_118692435 2.49 ENSMUST00000028807.6
isovaleryl coenzyme A dehydrogenase
chr4_+_43983472 2.46 ENSMUST00000095107.3
calicin
chr10_-_17823736 2.40 ENSMUST00000037879.8
hdc homolog, cell cycle regulator
chr5_-_5564873 2.40 ENSMUST00000060947.14
claudin 12
chr7_-_24033346 2.35 ENSMUST00000069562.6
tescalcin-like
chr3_-_92528480 2.35 ENSMUST00000170676.3
late cornified envelope 6A
chr12_+_86468401 2.31 ENSMUST00000110203.8
ENSMUST00000110204.9
estrogen related receptor, beta
chr19_+_43741431 2.27 ENSMUST00000026199.14
cutC copper transporter
chrX_+_11165496 2.25 ENSMUST00000188439.2
H2A histone family member L1A
chr5_-_86780277 2.23 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr19_+_43741513 2.22 ENSMUST00000112047.10
cutC copper transporter
chr2_+_18703797 2.22 ENSMUST00000095132.10
sperm associated antigen 6
chrX_-_55643429 2.19 ENSMUST00000059899.3
membrane magnesium transporter 1
chr7_+_44145987 2.14 ENSMUST00000107927.5
family with sequence similarity 71, member E1
chr12_-_114380515 2.11 ENSMUST00000179796.2
immunoglobulin heavy variable V6-5
chrX_+_117336912 2.07 ENSMUST00000072518.8
TGFB-induced factor homeobox 2-like, X-linked 2
chrX_+_93278203 2.06 ENSMUST00000153900.8
kelch-like 15
chr12_-_110945376 2.05 ENSMUST00000142012.2
ankyrin repeat domain 9
chr3_+_129326285 2.05 ENSMUST00000197235.5
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr13_-_35108293 2.04 ENSMUST00000223834.2
family with sequence similarity 217, member A
chr11_+_105885461 2.03 ENSMUST00000190995.2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr8_+_95113066 2.03 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr18_+_21205386 2.02 ENSMUST00000082235.5
meprin 1 beta
chr7_-_34755985 2.01 ENSMUST00000130491.3
CCAAT/enhancer binding protein (C/EBP), gamma
chr16_-_94171556 2.00 ENSMUST00000113906.9
phosphatidylinositol glycan anchor biosynthesis, class P
chr4_-_118792037 2.00 ENSMUST00000081960.5
olfactory receptor 1328
chr1_+_33947250 1.98 ENSMUST00000183034.5
dystonin
chr5_+_91222470 1.98 ENSMUST00000031324.6
epiregulin
chr2_+_158344553 1.98 ENSMUST00000109484.2
adipogenin
chr3_+_99203818 1.97 ENSMUST00000150756.3
T-box 15
chr18_-_42329765 1.97 ENSMUST00000236636.2
PLAC8-like 1
chr7_+_45271229 1.97 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr12_-_110945415 1.95 ENSMUST00000135131.2
ENSMUST00000043459.13
ENSMUST00000128353.8
ankyrin repeat domain 9
chr4_+_47208004 1.94 ENSMUST00000082303.13
ENSMUST00000102917.11
collagen, type XV, alpha 1
chr18_+_57666852 1.94 ENSMUST00000079738.10
ENSMUST00000135806.8
ENSMUST00000127130.9
coiled-coil domain containing 192
chr13_-_98831276 1.93 ENSMUST00000148950.2
transmembrane protein 171
chr2_+_158344532 1.93 ENSMUST00000059889.4
adipogenin
chr10_-_95678786 1.92 ENSMUST00000211096.2
predicted gene, 33543
chr10_-_31321793 1.90 ENSMUST00000213639.2
ENSMUST00000215515.2
ENSMUST00000214644.2
ENSMUST00000213528.2
tumor protein D52-like 1
chr15_+_44482667 1.88 ENSMUST00000228648.2
ENSMUST00000226165.2
estrogen receptor-binding fragment-associated gene 9
chr10_+_69055215 1.87 ENSMUST00000172261.3
Rho-related BTB domain containing 1
chr10_-_128657445 1.85 ENSMUST00000217685.2
ENSMUST00000026409.5
ENSMUST00000219215.2
ENSMUST00000219524.2
ORM1-like 2 (S. cerevisiae)
chr15_+_99291455 1.84 ENSMUST00000162624.8
transmembrane BAX inhibitor motif containing 6
chr18_-_35631914 1.84 ENSMUST00000236007.2
ENSMUST00000237896.2
ENSMUST00000235778.2
ENSMUST00000235524.2
ENSMUST00000235691.2
ENSMUST00000235619.2
ENSMUST00000025215.10
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr15_-_38079089 1.82 ENSMUST00000110336.4
ubiquitin protein ligase E3 component n-recognin 5
chr16_-_94171533 1.80 ENSMUST00000113910.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr13_-_74956924 1.77 ENSMUST00000223206.2
calpastatin
chr12_+_37291728 1.74 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr7_+_44146029 1.70 ENSMUST00000205359.2
family with sequence similarity 71, member E1
chr12_-_110945052 1.69 ENSMUST00000140788.8
ankyrin repeat domain 9
chr7_+_44146012 1.69 ENSMUST00000205422.2
family with sequence similarity 71, member E1
chr18_-_42329744 1.68 ENSMUST00000081374.4
PLAC8-like 1
chr13_-_74956640 1.68 ENSMUST00000231578.2
calpastatin
chr2_-_104324035 1.67 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr8_+_124204598 1.64 ENSMUST00000001520.13
AFG3-like AAA ATPase 1
chr3_+_96011810 1.63 ENSMUST00000132980.8
ENSMUST00000138206.8
ENSMUST00000090785.9
ENSMUST00000035519.12
OTU domain containing 7B
chrX_+_162922317 1.62 ENSMUST00000112271.10
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr2_+_103858066 1.62 ENSMUST00000028603.10
F-box protein 3
chr9_-_59393893 1.62 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chr9_+_108216466 1.60 ENSMUST00000193987.2
glutathione peroxidase 1
chr13_-_31131742 1.60 ENSMUST00000102943.2
HUS1 checkpoint clamp component B
chr14_-_32407203 1.58 ENSMUST00000096038.4
RIKEN cDNA 3425401B19 gene
chr2_+_132689640 1.58 ENSMUST00000124836.8
ENSMUST00000154160.2
cardiolipin synthase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0097037 heme export(GO:0097037)
2.7 10.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
2.5 7.6 GO:2000487 asparagine transport(GO:0006867) positive regulation of glutamine transport(GO:2000487)
2.3 7.0 GO:0015881 creatine transport(GO:0015881)
2.3 6.8 GO:0006553 lysine metabolic process(GO:0006553)
2.3 18.1 GO:0015722 canalicular bile acid transport(GO:0015722)
2.1 6.4 GO:0009087 methionine catabolic process(GO:0009087)
2.0 7.8 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
1.8 59.1 GO:0035634 response to stilbenoid(GO:0035634)
1.8 16.0 GO:0006572 tyrosine catabolic process(GO:0006572)
1.6 6.4 GO:0042851 L-alanine metabolic process(GO:0042851)
1.6 11.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.5 4.5 GO:0018879 biphenyl metabolic process(GO:0018879)
1.2 3.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.2 3.6 GO:0071288 cellular response to mercury ion(GO:0071288)
1.1 14.9 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.1 4.5 GO:0010269 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
1.1 7.7 GO:0042256 mature ribosome assembly(GO:0042256)
1.0 5.0 GO:1904970 brush border assembly(GO:1904970)
0.9 9.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.8 9.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.8 7.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 5.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.7 5.2 GO:0002003 angiotensin maturation(GO:0002003)
0.7 6.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.7 3.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.6 5.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.6 3.1 GO:0031437 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6 5.4 GO:0061709 reticulophagy(GO:0061709)
0.6 9.0 GO:0015747 urate transport(GO:0015747)
0.6 2.9 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.6 2.3 GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.6 3.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.5 13.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.5 6.6 GO:0006020 inositol metabolic process(GO:0006020)
0.5 3.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.5 1.9 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.5 1.4 GO:0010040 response to iron(II) ion(GO:0010040)
0.5 1.8 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.4 1.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 7.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 2.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 24.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.4 2.6 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.4 1.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.4 1.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 2.0 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 1.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 9.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 2.8 GO:0070417 cellular response to cold(GO:0070417)
0.3 0.9 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 2.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 0.9 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.3 1.4 GO:0046449 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.3 2.0 GO:0015862 uridine transport(GO:0015862)
0.3 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.3 1.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 1.5 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 3.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 2.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 3.4 GO:0007343 egg activation(GO:0007343)
0.2 0.9 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.2 2.5 GO:0006551 leucine metabolic process(GO:0006551)
0.2 12.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 1.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.2 2.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 3.0 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.2 2.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.2 2.8 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 2.0 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 2.2 GO:0006824 cobalt ion transport(GO:0006824)
0.1 2.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 3.8 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 3.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 6.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 1.0 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 2.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 3.9 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 2.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 4.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.2 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 3.1 GO:0014823 response to activity(GO:0014823)
0.1 2.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.6 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 5.8 GO:0007566 embryo implantation(GO:0007566)
0.1 0.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 5.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.1 GO:0007635 chemosensory behavior(GO:0007635)
0.1 2.3 GO:0033198 response to ATP(GO:0033198)
0.1 6.3 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 2.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 3.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 1.0 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.1 4.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 4.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 5.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.4 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 7.0 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 2.0 GO:1901998 toxin transport(GO:1901998)
0.0 2.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 1.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 2.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 2.5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.0 2.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 4.7 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 4.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 3.7 GO:0016485 protein processing(GO:0016485)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0061474 phagolysosome membrane(GO:0061474)
3.6 14.6 GO:0046691 intracellular canaliculus(GO:0046691)
3.0 9.0 GO:0070195 growth hormone receptor complex(GO:0070195)
1.3 10.7 GO:0045293 mRNA editing complex(GO:0045293)
1.0 8.1 GO:0097413 Lewy body(GO:0097413)
0.7 6.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 2.8 GO:0005879 axonemal microtubule(GO:0005879)
0.6 2.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 2.0 GO:0070722 Tle3-Aes complex(GO:0070722)
0.4 1.6 GO:0005745 m-AAA complex(GO:0005745)
0.4 3.6 GO:0005577 fibrinogen complex(GO:0005577)
0.4 2.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 1.9 GO:0035339 SPOTS complex(GO:0035339)
0.4 1.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.3 32.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 4.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 3.5 GO:0031983 vesicle lumen(GO:0031983)
0.3 2.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 2.8 GO:0071546 pi-body(GO:0071546)
0.2 2.0 GO:0031673 H zone(GO:0031673)
0.2 5.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 7.6 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.6 GO:0036128 CatSper complex(GO:0036128)
0.2 4.9 GO:0030008 TRAPP complex(GO:0030008)
0.2 6.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 3.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 3.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.0 GO:0031143 pseudopodium(GO:0031143)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 3.1 GO:0032982 myosin filament(GO:0032982)
0.1 7.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.3 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.6 GO:0044754 autolysosome(GO:0044754)
0.1 9.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 11.1 GO:0036126 sperm flagellum(GO:0036126)
0.1 26.4 GO:0072562 blood microparticle(GO:0072562)
0.1 3.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 13.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 4.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 4.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 2.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 5.4 GO:0031514 motile cilium(GO:0031514)
0.1 6.7 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 5.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 4.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 18.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 3.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 8.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.7 GO:0030141 secretory granule(GO:0030141)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 5.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 22.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0004903 growth hormone receptor activity(GO:0004903)
2.8 11.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
2.7 8.1 GO:0070401 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
2.6 7.7 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
2.3 7.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
1.9 7.6 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
1.9 9.5 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
1.8 14.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 6.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.3 3.9 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.3 6.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.2 3.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.1 6.8 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.1 41.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.0 7.3 GO:0001851 complement component C3b binding(GO:0001851)
1.0 18.1 GO:0015250 water channel activity(GO:0015250)
1.0 22.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 5.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.8 24.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.8 2.3 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.8 5.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.8 6.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 12.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.7 3.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.7 1.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 22.6 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.6 3.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.6 3.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.6 5.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 9.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5 7.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 3.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.5 3.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 2.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 2.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 15.5 GO:0042056 chemoattractant activity(GO:0042056)
0.4 39.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 1.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.4 3.6 GO:0045340 mercury ion binding(GO:0045340)
0.3 11.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.3 1.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.3 4.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 4.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.3 5.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 0.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 2.2 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 1.5 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.2 4.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 2.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 7.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 1.4 GO:0004630 phospholipase D activity(GO:0004630)
0.1 3.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 4.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0070052 collagen V binding(GO:0070052)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 3.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 8.5 GO:0005507 copper ion binding(GO:0005507)
0.1 2.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 2.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 4.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 6.7 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.0 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 3.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 2.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 8.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 14.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 5.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 5.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 8.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 18.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.3 14.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 35.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 7.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 6.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 9.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 7.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 9.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 11.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 6.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 4.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 12.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 3.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 4.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 12.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 2.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 15.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 3.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 9.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 3.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression