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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hmbox1

Z-value: 1.15

Motif logo

Transcription factors associated with Hmbox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021972.15 Hmbox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmbox1mm39_v1_chr14_-_65187287_65187335-0.318.9e-03Click!

Activity profile of Hmbox1 motif

Sorted Z-values of Hmbox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmbox1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_28752050 8.81 ENSMUST00000029240.14
solute carrier family 2 (facilitated glucose transporter), member 2
chr1_+_21310821 7.83 ENSMUST00000121676.8
ENSMUST00000124990.3
glutathione S-transferase, alpha 3
chr1_+_21310803 7.65 ENSMUST00000027067.15
glutathione S-transferase, alpha 3
chr4_+_117109204 7.48 ENSMUST00000125943.8
ENSMUST00000106434.8
transmembrane protein 53
chr4_+_100336003 7.15 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr11_+_22958338 7.04 ENSMUST00000172602.9
family with sequence similarity 161, member A
chr11_+_22958418 7.03 ENSMUST00000109557.10
family with sequence similarity 161, member A
chr6_-_113411718 6.58 ENSMUST00000113091.8
cell death-inducing DFFA-like effector c
chr1_+_88128323 6.47 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr4_+_98919183 5.92 ENSMUST00000030280.7
angiopoietin-like 3
chr11_-_88742285 5.38 ENSMUST00000107903.8
A kinase (PRKA) anchor protein 1
chr13_+_4484305 5.02 ENSMUST00000021630.15
aldo-keto reductase family 1, member C6
chr19_+_32573182 4.95 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_+_87148697 4.85 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr8_-_45715049 4.85 ENSMUST00000034064.5
coagulation factor XI
chr2_+_70339157 4.78 ENSMUST00000100041.9
glutamate rich 2
chr2_+_70339175 4.73 ENSMUST00000134607.8
glutamate rich 2
chr8_-_106863423 4.40 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr8_-_106863521 4.34 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr7_-_44711075 4.34 ENSMUST00000007981.9
ENSMUST00000210500.2
ENSMUST00000210493.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr19_-_28945194 4.31 ENSMUST00000162110.8
spermatogenesis associated 6 like
chr2_+_34764408 4.30 ENSMUST00000113068.9
ENSMUST00000047447.13
cutA divalent cation tolerance homolog-like
chr18_-_10706701 4.20 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr6_-_24168082 4.11 ENSMUST00000031713.9
solute carrier family 13 (sodium/sulfate symporters), member 1
chr18_-_3281089 4.09 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr11_-_94398162 3.82 ENSMUST00000040692.9
MYCBP associated protein
chr2_+_173561208 3.82 ENSMUST00000073081.6
RIKEN cDNA 1700010B08 gene
chr18_-_3280999 3.80 ENSMUST00000049942.13
cAMP responsive element modulator
chr7_-_44711130 3.75 ENSMUST00000211337.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr1_-_185849448 3.69 ENSMUST00000045388.8
lysophospholipase-like 1
chr13_-_73826124 3.67 ENSMUST00000022105.15
ENSMUST00000109680.10
ENSMUST00000221026.2
ENSMUST00000109679.4
solute carrier family 6 (neurotransmitter transporter), member 18
chr11_-_78313043 3.61 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_+_52596266 3.60 ENSMUST00000029995.6
topoisomerase I binding, arginine/serine-rich like
chr2_+_34764496 3.59 ENSMUST00000028228.6
cutA divalent cation tolerance homolog-like
chr4_+_128887017 3.49 ENSMUST00000030583.13
ENSMUST00000102604.11
adenylate kinase 2
chr10_-_39009910 3.47 ENSMUST00000135785.8
family with sequence similarity 229, member B
chr19_+_6155804 3.44 ENSMUST00000044451.4
N-acetylated alpha-linked acidic dipeptidase-like 1
chr16_-_43836681 3.38 ENSMUST00000036174.10
GRAM domain containing 1C
chr10_-_39009844 3.28 ENSMUST00000134279.8
ENSMUST00000139743.8
ENSMUST00000149949.8
ENSMUST00000124941.8
ENSMUST00000125042.8
ENSMUST00000063204.9
family with sequence similarity 229, member B
chr19_+_39275518 3.24 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr16_-_21814190 3.22 ENSMUST00000231766.2
ENSMUST00000074230.12
lipase, member H
chr2_+_70339832 3.13 ENSMUST00000153121.2
glutamate rich 2
chrX_+_162873183 3.13 ENSMUST00000015545.10
collectrin, amino acid transport regulator
chr15_+_54975713 3.12 ENSMUST00000096433.10
DEP domain containing MTOR-interacting protein
chr11_-_94932158 3.08 ENSMUST00000038431.8
pyruvate dehydrogenase kinase, isoenzyme 2
chr9_+_106391771 3.05 ENSMUST00000085113.5
IQ motif containing F5
chrM_+_5319 3.02 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr7_+_134870237 2.98 ENSMUST00000210697.2
ENSMUST00000097983.5
neuropeptide S
chr4_+_20042045 2.95 ENSMUST00000098242.4
gamma-glutamyl hydrolase
chr11_+_31822211 2.84 ENSMUST00000020543.13
ENSMUST00000109412.9
cytoplasmic polyadenylation element binding protein 4
chr13_+_22220000 2.80 ENSMUST00000110455.4
H2B clustered histone 12
chr6_+_30610973 2.76 ENSMUST00000062758.11
carboxypeptidase A5
chr1_+_163979384 2.75 ENSMUST00000086040.6
coagulation factor V
chr13_-_73826108 2.72 ENSMUST00000222029.2
ENSMUST00000223074.2
ENSMUST00000220650.2
ENSMUST00000221987.2
solute carrier family 6 (neurotransmitter transporter), member 18
chr8_+_46387647 2.70 ENSMUST00000095326.10
coiled-coil domain containing 110
chr4_+_51216645 2.65 ENSMUST00000166749.2
ENSMUST00000156384.4
cylicin, basic protein of sperm head cytoskeleton 2
chr7_-_130748035 2.65 ENSMUST00000070980.4
RIKEN cDNA 4933402N03 gene
chr6_+_30611028 2.62 ENSMUST00000115138.8
carboxypeptidase A5
chr16_-_21814289 2.62 ENSMUST00000060673.8
lipase, member H
chr4_-_58987094 2.59 ENSMUST00000030069.7
prostaglandin reductase 1
chr9_-_71075939 2.59 ENSMUST00000113570.8
aquaporin 9
chr6_+_5390386 2.58 ENSMUST00000183358.2
ankyrin repeat and SOCS box-containing 4
chr13_-_35108293 2.56 ENSMUST00000223834.2
family with sequence similarity 217, member A
chr10_+_100428212 2.55 ENSMUST00000187119.7
ENSMUST00000188736.7
ENSMUST00000191336.7
RIKEN cDNA 1700017N19 gene
chr9_-_78275430 2.54 ENSMUST00000071991.6
developmental pluripotency associated 5A
chr6_+_29853745 2.49 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr3_-_79749949 2.46 ENSMUST00000029568.7
transmembrane protein 144
chr15_+_54975814 2.43 ENSMUST00000100660.11
DEP domain containing MTOR-interacting protein
chr10_+_100428246 2.38 ENSMUST00000041162.13
ENSMUST00000190386.7
ENSMUST00000190708.7
RIKEN cDNA 1700017N19 gene
chr1_+_31261889 2.36 ENSMUST00000027230.3
dynein axonemal assembly factor 6
chr15_-_100576715 2.33 ENSMUST00000229869.2
chymotrypsin-like elastase family, member 1
chr4_-_63090355 2.29 ENSMUST00000156618.9
ENSMUST00000030042.3
kinesin family member 12
chr3_+_132335704 2.27 ENSMUST00000212594.2
GIMAP family P-loop NTPase domain containing 1
chr7_-_39062584 2.25 ENSMUST00000108017.2
predicted gene 5114
chr13_+_68011442 2.24 ENSMUST00000078471.7
cDNA sequence BC048507
chr17_+_41245569 2.23 ENSMUST00000169611.4
methylmalonyl-Coenzyme A mutase
chr12_+_52144511 2.23 ENSMUST00000040090.16
nucleotide binding protein-like
chr8_-_94739469 2.21 ENSMUST00000053766.14
autocrine motility factor receptor
chr11_+_51654511 2.21 ENSMUST00000020653.6
secretion associated Ras related GTPase 1B
chr13_-_96678844 2.19 ENSMUST00000223475.2
polymerase (DNA directed), kappa
chr5_+_7354130 2.17 ENSMUST00000160634.2
ENSMUST00000159546.2
testis expressed 47
chr1_+_88154727 2.14 ENSMUST00000061013.13
ENSMUST00000113130.8
maestro heat-like repeat family member 2A
chr7_-_38227617 2.13 ENSMUST00000079759.6
predicted gene 5591
chr12_+_36364136 2.11 ENSMUST00000041407.7
sclerostin domain containing 1
chr2_+_3771709 2.07 ENSMUST00000177037.2
family with sequence similarity 107, member B
chr11_+_11414256 2.06 ENSMUST00000020410.11
spermatogenesis associated 48
chrX_+_42680037 2.02 ENSMUST00000105113.4
TEX13 family member C1
chr2_+_85551751 1.95 ENSMUST00000055517.3
olfactory receptor 1009
chr13_-_3943556 1.94 ENSMUST00000099946.6
neuroepithelial cell transforming gene 1
chrX_+_156482116 1.85 ENSMUST00000112521.8
small muscle protein, X-linked
chrX_+_143239577 1.83 ENSMUST00000155206.8
transient receptor potential cation channel, subfamily C, member 5, opposite strand
chr19_+_47854249 1.81 ENSMUST00000238084.2
glutathione S-transferase omega 2
chr7_-_25516041 1.80 ENSMUST00000043314.10
cytochrome P450, family 2, subfamily s, polypeptide 1
chr9_-_49397508 1.74 ENSMUST00000055096.5
tetratricopeptide repeat domain 12
chr12_-_81579614 1.73 ENSMUST00000169158.2
ENSMUST00000164431.2
ENSMUST00000163402.8
ENSMUST00000166664.2
ENSMUST00000164386.8
synaptojanin 2 binding protein
predicted gene 20498
chr9_-_119812042 1.72 ENSMUST00000214058.2
cysteine-serine-rich nuclear protein 1
chr19_-_4977997 1.69 ENSMUST00000236758.2
dipeptidylpeptidase 3
chr11_+_73068063 1.68 ENSMUST00000108477.2
Tax1 (human T cell leukemia virus type I) binding protein 3
chr14_+_54413727 1.64 ENSMUST00000103701.2
T cell receptor alpha joining 41
chr13_-_3943433 1.64 ENSMUST00000222504.2
neuroepithelial cell transforming gene 1
chr11_+_73067909 1.64 ENSMUST00000040687.12
Tax1 (human T cell leukemia virus type I) binding protein 3
chr19_+_45003304 1.59 ENSMUST00000039016.14
leucine zipper, putative tumor suppressor 2
chr12_+_65012564 1.57 ENSMUST00000066296.9
ENSMUST00000223166.2
TOG array regulator of axonemal microtubules 1
chr4_-_133066594 1.50 ENSMUST00000043305.14
WD and tetratricopeptide repeats 1
chr5_+_7354113 1.49 ENSMUST00000088796.3
testis expressed 47
chr4_-_133066549 1.49 ENSMUST00000105906.2
WD and tetratricopeptide repeats 1
chr13_+_55359598 1.47 ENSMUST00000224918.2
nuclear receptor-binding SET-domain protein 1
chr7_+_40682143 1.46 ENSMUST00000164422.2
predicted gene 4884
chr10_-_95159933 1.46 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr19_-_32080496 1.41 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr13_+_55359866 1.40 ENSMUST00000224693.2
nuclear receptor-binding SET-domain protein 1
chr1_+_52884172 1.40 ENSMUST00000159352.8
ENSMUST00000044478.7
3-hydroxyisobutyryl-Coenzyme A hydrolase
chr1_-_31261678 1.36 ENSMUST00000187892.8
ENSMUST00000233331.2
RIKEN cDNA 4931428L18 gene
chr2_+_20742115 1.21 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr5_+_136721938 1.20 ENSMUST00000196068.5
ENSMUST00000005611.10
myosin, light chain 10, regulatory
chrX_+_156481906 1.19 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chrX_-_65347749 1.16 ENSMUST00000033525.3
RIKEN cDNA 4930447F04 gene
chr10_+_20024203 1.14 ENSMUST00000020173.16
microtubule-associated protein 7
chr15_+_99291491 1.09 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr4_-_141450710 1.00 ENSMUST00000102484.5
ENSMUST00000177592.2
DNA-damage inducible protein 2
chr6_+_43150886 0.99 ENSMUST00000059512.5
olfactory receptor 13
chr3_+_95496239 0.95 ENSMUST00000177390.8
ENSMUST00000060323.12
ENSMUST00000098861.11
golgi phosphoprotein 3-like
chr5_+_62968993 0.93 ENSMUST00000238474.2
death domain containing 1
chr11_+_77576981 0.92 ENSMUST00000100802.11
ENSMUST00000181023.2
nuclear fragile X mental retardation protein interacting protein 2
chr10_+_129072073 0.91 ENSMUST00000203248.3
olfactory receptor 774
chr14_-_36628263 0.90 ENSMUST00000183007.2
coiled-coil serine rich 2
chr14_-_70561231 0.90 ENSMUST00000151011.8
solute carrier family 39 (zinc transporter), member 14
chr11_+_75541324 0.80 ENSMUST00000102505.10
myosin IC
chr6_-_97156032 0.79 ENSMUST00000095664.6
TATA element modulatory factor 1
chr11_-_73067828 0.78 ENSMUST00000108480.2
ENSMUST00000054952.4
ER membrane protein complex subunit 6
chr1_+_155916655 0.76 ENSMUST00000065648.15
ENSMUST00000097526.3
torsin A interacting protein 2
chr13_+_56757389 0.76 ENSMUST00000045173.10
transforming growth factor, beta induced
chr9_+_119170360 0.75 ENSMUST00000039784.12
acetyl-Coenzyme A acyltransferase 1A
chrX_+_141464722 0.73 ENSMUST00000112896.9
transmembrane protein 164
chr2_+_146854916 0.72 ENSMUST00000028921.6
5'-3' exoribonuclease 2
chr17_+_35055962 0.71 ENSMUST00000173874.8
ENSMUST00000180043.8
ENSMUST00000046244.15
decapping exoribonuclease
chr3_+_95496270 0.68 ENSMUST00000176674.8
ENSMUST00000177389.8
ENSMUST00000176755.8
ENSMUST00000177399.2
golgi phosphoprotein 3-like
chr3_-_95125002 0.65 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr13_+_47347301 0.63 ENSMUST00000110111.4
ring finger protein 144B
chr2_+_119039456 0.61 ENSMUST00000102519.5
zinc finger, FYVE domain containing 19
chr3_+_144824325 0.61 ENSMUST00000098538.9
ENSMUST00000106192.9
ENSMUST00000098539.7
ENSMUST00000029920.15
outer dense fiber of sperm tails 2-like
chr3_-_57202301 0.60 ENSMUST00000171384.8
transmembrane 4 superfamily member 1
chr5_-_143963413 0.58 ENSMUST00000031622.13
oncomodulin
chr10_-_12743915 0.57 ENSMUST00000219584.2
utrophin
chr2_+_32253692 0.56 ENSMUST00000113331.8
ENSMUST00000113338.9
CDKN1A interacting zinc finger protein 1
chr1_+_24216691 0.56 ENSMUST00000054588.15
collagen, type IX, alpha 1
chrX_+_20982059 0.54 ENSMUST00000072593.9
synovial sarcoma, X member A1
chr3_+_144824644 0.54 ENSMUST00000199124.5
outer dense fiber of sperm tails 2-like
chr16_+_3408906 0.53 ENSMUST00000216259.2
olfactory receptor 161
chrX_-_110440860 0.52 ENSMUST00000128819.8
ribosomal protein S6 kinase polypeptide 6
chr17_+_74645936 0.51 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
spastin
chr10_-_52071340 0.49 ENSMUST00000020045.10
Ros1 proto-oncogene
chr4_+_116414855 0.48 ENSMUST00000030460.15
GC-rich promoter binding protein 1-like 1
chr3_-_64049349 0.48 ENSMUST00000177151.9
vomeronasal 2, receptor 2
chr10_-_128885867 0.47 ENSMUST00000216460.2
olfactory receptor 765
chr4_+_116415251 0.45 ENSMUST00000106475.2
GC-rich promoter binding protein 1-like 1
chr3_+_108561223 0.44 ENSMUST00000106609.8
chloride channel CLIC-like 1
chr10_-_129710624 0.42 ENSMUST00000081367.2
olfactory receptor 814
chr19_+_45003635 0.41 ENSMUST00000179108.9
leucine zipper, putative tumor suppressor 2
chr3_+_108561294 0.40 ENSMUST00000106613.2
chloride channel CLIC-like 1
chr5_-_143963461 0.40 ENSMUST00000110702.2
oncomodulin
chr10_-_128918779 0.39 ENSMUST00000213579.2
olfactory receptor 767
chr2_-_12424212 0.39 ENSMUST00000124603.8
ENSMUST00000129993.3
ENSMUST00000028105.13
MINDY lysine 48 deubiquitinase 3
chr3_-_104960264 0.38 ENSMUST00000098763.7
ENSMUST00000197437.5
CTTNBP2 N-terminal like
chr8_-_106074585 0.38 ENSMUST00000014922.5
formin homology 2 domain containing 1
chr15_+_100320028 0.36 ENSMUST00000132119.2
predicted gene 5475
chr3_+_108561247 0.36 ENSMUST00000124384.8
ENSMUST00000029483.15
chloride channel CLIC-like 1
chr1_+_173093568 0.35 ENSMUST00000213420.2
olfactory receptor 418
chr5_+_104318542 0.34 ENSMUST00000112771.2
dentin sialophosphoprotein
chr1_-_131025562 0.33 ENSMUST00000016672.11
MAP kinase-activated protein kinase 2
chr4_+_152423075 0.31 ENSMUST00000030775.12
ENSMUST00000164662.8
chromodomain helicase DNA binding protein 5
chr7_-_47677345 0.31 ENSMUST00000094390.3
MAS-related GPR, member X1
chr17_-_31877703 0.24 ENSMUST00000236475.2
ENSMUST00000166526.9
ENSMUST00000014684.6
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
chr8_+_110806390 0.23 ENSMUST00000212754.2
ENSMUST00000058804.10
zinc finger protein 612
chr10_-_40133558 0.22 ENSMUST00000216847.2
ENSMUST00000213628.2
ENSMUST00000217537.2
ENSMUST00000019982.9
general transcription factor IIIC, polypeptide 6, alpha
chr1_+_192856044 0.22 ENSMUST00000193307.2
RIKEN cDNA A130010J15 gene
chr12_+_103524690 0.21 ENSMUST00000187155.7
protein phosphatase 4, regulatory subunit 4
chr14_-_55101505 0.21 ENSMUST00000142283.4
homeodomain leucine zipper-encoding gene
chr5_+_88117307 0.20 ENSMUST00000007601.4
ENSMUST00000187738.2
RIKEN cDNA 2310003L06 gene
predicted gene 28434
chr11_+_49321254 0.20 ENSMUST00000203369.2
olfactory receptor 1389
chr4_-_155170738 0.19 ENSMUST00000030914.4
retention in endoplasmic reticulum sorting receptor 1
chr2_+_85838122 0.19 ENSMUST00000062166.2
olfactory receptor 1032
chr1_-_69726384 0.19 ENSMUST00000187184.7
IKAROS family zinc finger 2
chr10_-_52071052 0.17 ENSMUST00000218452.2
Ros1 proto-oncogene
chr11_+_101358990 0.17 ENSMUST00000001347.7
Rho family GTPase 2
chr16_+_35803794 0.17 ENSMUST00000173555.8
karyopherin (importin) alpha 1
chr3_+_94350622 0.16 ENSMUST00000029786.14
ENSMUST00000196143.2
mitochondrial ribosomal protein L9
chr19_+_45003670 0.13 ENSMUST00000236377.2
leucine zipper, putative tumor suppressor 2
chr1_-_131207279 0.11 ENSMUST00000062108.10
inhibitor of kappaB kinase epsilon
chr11_-_4654303 0.10 ENSMUST00000058407.6
ubiquinol-cytochrome c reductase, complex III subunit X
chr10_+_4296806 0.10 ENSMUST00000216139.3
A kinase (PRKA) anchor protein (gravin) 12
chr3_+_93227047 0.07 ENSMUST00000090856.10
ENSMUST00000093774.4
hornerin
chr15_+_25774070 0.07 ENSMUST00000125667.3
myosin X
chr18_+_35695736 0.07 ENSMUST00000235851.2
ENSMUST00000235581.2
matrin 3
chr11_+_96909559 0.03 ENSMUST00000107622.2
trans-acting transcription factor 6
chr1_-_171476495 0.02 ENSMUST00000194791.2
ENSMUST00000192024.6
SLAM family member 7
chr14_-_79461316 0.02 ENSMUST00000040802.5
zinc finger protein 957
chr1_-_144427302 0.02 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr13_+_49658249 0.01 ENSMUST00000051504.8
extracellular matrix protein 2, female organ and adipocyte specific
chr14_+_27344385 0.01 ENSMUST00000210135.2
ENSMUST00000090302.6
ENSMUST00000211087.2
ELKS/RAB6-interacting/CAST family member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
1.8 8.8 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.7 5.0 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.2 5.0 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.0 5.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.0 4.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.8 3.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.7 3.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 2.6 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.6 3.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.6 5.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.6 3.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.5 6.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 2.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.5 3.0 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.3 2.3 GO:0060309 elastin catabolic process(GO:0060309)
0.3 2.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 0.8 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.3 6.6 GO:0034389 lipid particle organization(GO:0034389)
0.3 2.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 1.8 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.2 2.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 5.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.1 GO:0031437 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 2.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 2.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 2.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.2 1.0 GO:1902336 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 3.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 4.1 GO:0008272 sulfate transport(GO:0008272)
0.2 8.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 3.6 GO:0051451 myoblast migration(GO:0051451)
0.2 5.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 3.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 3.3 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.7 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 9.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 2.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175) cellular response to cell-matrix adhesion(GO:0071460)
0.1 6.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 1.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 5.9 GO:0016574 histone ubiquitination(GO:0016574)
0.1 4.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 1.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.0 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.7 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 9.5 GO:0044782 cilium organization(GO:0044782)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 1.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 2.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 1.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 2.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 5.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 2.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 1.4 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.9 7.1 GO:0033503 HULC complex(GO:0033503)
0.6 3.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 3.0 GO:0005927 muscle tendon junction(GO:0005927)
0.4 2.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 5.4 GO:0030061 mitochondrial crista(GO:0030061)
0.3 14.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 0.8 GO:0045160 myosin I complex(GO:0045160)
0.2 3.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 2.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.8 GO:1903349 omegasome membrane(GO:1903349)
0.1 14.2 GO:0031526 brush border membrane(GO:0031526)
0.1 2.8 GO:0031091 platelet alpha granule(GO:0031091)
0.1 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 2.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 4.7 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 6.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 37.7 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.8 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
1.7 5.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.2 5.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.8 3.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 4.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.6 2.6 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.5 3.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 5.9 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.5 2.6 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 2.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.4 2.9 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4 3.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 5.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.4 2.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 17.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 4.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 11.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.7 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.2 3.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.7 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 5.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 4.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 2.1 GO:0098821 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.2 6.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 3.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 1.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 1.4 GO:0017040 ceramidase activity(GO:0017040)
0.2 3.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 2.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 3.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 10.6 GO:0005507 copper ion binding(GO:0005507)
0.1 3.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.5 GO:0070513 death domain binding(GO:0070513)
0.1 2.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.8 GO:0070330 aromatase activity(GO:0070330)
0.1 2.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 5.8 GO:0004620 phospholipase activity(GO:0004620)
0.0 2.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 10.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.5 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.7 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.4 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 7.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 10.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 10.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 8.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 5.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 6.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 3.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 7.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 5.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 17.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 6.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 5.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 9.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation