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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hmx1

Z-value: 1.22

Motif logo

Transcription factors associated with Hmx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000067438.6 Hmx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmx1mm39_v1_chr5_+_35546363_35546461-0.413.3e-04Click!

Activity profile of Hmx1 motif

Sorted Z-values of Hmx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_135656885 8.91 ENSMUST00000027677.8
cysteine and glycine-rich protein 1
chr7_+_18618605 7.64 ENSMUST00000032573.8
peptidoglycan recognition protein 1
chr13_+_91609169 7.63 ENSMUST00000004094.15
ENSMUST00000042122.15
single-stranded DNA binding protein 2
chr13_+_91609264 7.46 ENSMUST00000231481.2
single-stranded DNA binding protein 2
chr11_+_11636213 7.31 ENSMUST00000076700.11
ENSMUST00000048122.13
IKAROS family zinc finger 1
chr9_-_21223551 7.30 ENSMUST00000003397.9
ENSMUST00000213250.2
adaptor protein complex AP-1, mu 2 subunit
chr6_-_67512768 6.60 ENSMUST00000058178.6
tumor-associated calcium signal transducer 2
chrX_-_73290140 5.81 ENSMUST00000101454.9
ENSMUST00000033699.13
filamin, alpha
chr9_-_21223631 5.68 ENSMUST00000115433.11
adaptor protein complex AP-1, mu 2 subunit
chr12_+_36042899 5.65 ENSMUST00000020898.12
anterior gradient 2
chr15_-_79718423 5.53 ENSMUST00000109623.8
ENSMUST00000109625.8
ENSMUST00000023060.13
ENSMUST00000089299.6
chromobox 6
neuronal pentraxin chromo domain
chr3_-_92393193 5.40 ENSMUST00000054599.8
small proline-rich protein 1A
chr3_-_88455556 5.09 ENSMUST00000131775.2
ENSMUST00000008745.13
RAB25, member RAS oncogene family
chrX_-_73289970 5.00 ENSMUST00000130007.8
filamin, alpha
chrX_-_7537580 4.98 ENSMUST00000033486.6
proteolipid protein 2
chr2_+_164404499 4.62 ENSMUST00000017867.10
ENSMUST00000109344.9
ENSMUST00000109345.9
WAP four-disulfide core domain 2
chr11_+_69856222 4.58 ENSMUST00000018713.13
claudin 7
chrX_+_49930311 4.49 ENSMUST00000114887.9
serine/threonine kinase 26
chr2_-_113588983 4.48 ENSMUST00000099575.4
gremlin 1, DAN family BMP antagonist
chr12_+_51640097 4.43 ENSMUST00000164782.10
ENSMUST00000085412.7
cochlin
chr11_-_115258508 4.41 ENSMUST00000044152.13
ENSMUST00000106542.9
HID1 domain containing
chr15_-_79718462 4.28 ENSMUST00000148358.2
chromobox 6
chr6_+_41107047 4.08 ENSMUST00000103271.2
T cell receptor beta, variable 13-3
chr17_+_35413415 4.04 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr3_+_108498595 3.97 ENSMUST00000051145.15
WD repeat domain 47
chr4_+_134195631 3.93 ENSMUST00000030636.11
ENSMUST00000127279.8
ENSMUST00000105867.8
stathmin 1
chr2_+_92745426 3.90 ENSMUST00000028648.3
synaptotagmin XIII
chr17_-_34109513 3.88 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr13_+_55517545 3.86 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr4_-_152561896 3.66 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr2_+_165436929 3.61 ENSMUST00000088132.13
EYA transcriptional coactivator and phosphatase 2
chrX_-_133709733 3.53 ENSMUST00000035559.11
armadillo repeat containing, X-linked 2
chr7_-_83384711 3.52 ENSMUST00000001792.12
interleukin 16
chr6_-_127127959 3.51 ENSMUST00000201637.2
cyclin D2
chr14_-_79539063 3.49 ENSMUST00000022595.8
regulator of cell cycle
chr13_-_32522548 3.40 ENSMUST00000041859.9
GDP-mannose 4, 6-dehydratase
chrX_-_165368675 3.36 ENSMUST00000000412.3
EGF-like-domain, multiple 6
chr6_-_127127993 3.30 ENSMUST00000201066.2
cyclin D2
chr11_-_46203047 3.27 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr2_+_129040677 3.26 ENSMUST00000028880.10
solute carrier family 20, member 1
chr9_-_110483210 3.25 ENSMUST00000196488.5
ENSMUST00000133191.8
ENSMUST00000167320.8
neurobeachin-like 2
chr7_-_125968653 3.14 ENSMUST00000205642.2
ENSMUST00000032997.8
ENSMUST00000206793.2
linker for activation of T cells
chr15_-_78456898 3.12 ENSMUST00000043214.8
Rac family small GTPase 2
chr6_-_87312743 3.05 ENSMUST00000042025.12
ENSMUST00000205033.2
anthrax toxin receptor 1
chr2_+_152950388 2.98 ENSMUST00000189688.2
ENSMUST00000109799.8
ENSMUST00000003370.14
hemopoietic cell kinase
chr15_-_98507913 2.98 ENSMUST00000226500.2
ENSMUST00000227501.2
adenylate cyclase 6
chr15_+_78312764 2.97 ENSMUST00000162517.8
ENSMUST00000166142.10
ENSMUST00000089414.11
potassium channel tetramerisation domain containing 17
chr1_-_160134873 2.97 ENSMUST00000193185.6
RAB GTPase activating protein 1-like
chr1_+_152642291 2.95 ENSMUST00000077755.11
ENSMUST00000097536.6
actin related protein 2/3 complex, subunit 5
chr17_+_34811217 2.94 ENSMUST00000038149.13
pre B cell leukemia homeobox 2
chr5_-_34445662 2.92 ENSMUST00000094868.10
zinc finger, FYVE domain containing 28
chr11_+_23234644 2.90 ENSMUST00000150750.3
exportin 1
chr15_+_54609011 2.90 ENSMUST00000050027.9
cellular communication network factor 3
chr15_+_103411689 2.89 ENSMUST00000226493.2
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr2_+_32766126 2.88 ENSMUST00000028135.15
niban apoptosis regulator 2
chr15_+_78312851 2.86 ENSMUST00000159771.8
potassium channel tetramerisation domain containing 17
chr6_-_127128007 2.80 ENSMUST00000000188.12
cyclin D2
chr11_+_68322945 2.74 ENSMUST00000021283.8
phosphoinositide-3-kinase regulatory subunit 5
chr1_+_135252508 2.74 ENSMUST00000059352.3
leiomodin 1 (smooth muscle)
chr7_+_4467730 2.74 ENSMUST00000086372.8
ENSMUST00000169820.8
ENSMUST00000163893.8
ENSMUST00000170635.2
EPS8-like 1
chr11_+_44409775 2.62 ENSMUST00000019333.10
ring finger protein 145
chr6_-_124710084 2.62 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr1_+_61017057 2.59 ENSMUST00000027162.12
ENSMUST00000102827.4
inducible T cell co-stimulator
chr6_-_87312681 2.59 ENSMUST00000204805.3
anthrax toxin receptor 1
chr2_+_162916551 2.58 ENSMUST00000142729.3
myeloblastosis oncogene-like 2
chr9_-_42035560 2.55 ENSMUST00000060989.9
sortilin-related receptor, LDLR class A repeats-containing
chr11_-_115258493 2.53 ENSMUST00000123428.2
HID1 domain containing
chr19_-_14575395 2.50 ENSMUST00000052011.15
ENSMUST00000167776.3
transducin-like enhancer of split 4
chr8_+_121264161 2.48 ENSMUST00000118136.2
genetic suppressor element 1, coiled-coil protein
chr2_-_73284262 2.45 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr5_-_39801940 2.44 ENSMUST00000152057.2
ENSMUST00000053116.7
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr18_-_62313019 2.42 ENSMUST00000053640.5
adrenergic receptor, beta 2
chrX_-_151110425 2.41 ENSMUST00000195280.3
Kdm5c adjacent non-coding transcript
chr1_-_181669891 2.38 ENSMUST00000193028.2
ENSMUST00000191878.6
ENSMUST00000005003.12
lamin B receptor
chr5_-_134643805 2.34 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
linker for activation of T cells family, member 2
chr5_+_121358254 2.30 ENSMUST00000042614.13
HECT domain E3 ubiquitin protein ligase 4
chr9_+_95836797 2.26 ENSMUST00000034981.14
ENSMUST00000185633.7
5'-3' exoribonuclease 1
chr12_-_56392646 2.26 ENSMUST00000021416.9
MAP3K12 binding inhibitory protein 1
chr8_+_121262528 2.23 ENSMUST00000120493.8
genetic suppressor element 1, coiled-coil protein
chr17_+_27136065 2.21 ENSMUST00000078961.6
kinesin family member C5B
chr17_+_48769383 2.21 ENSMUST00000162132.8
unc-5 family C-terminal like
chr6_-_124710030 2.17 ENSMUST00000173647.2
protein tyrosine phosphatase, non-receptor type 6
chr11_+_120612278 2.16 ENSMUST00000018156.12
Rac family small GTPase 3
chr2_+_130116344 2.15 ENSMUST00000103198.11
NOP56 ribonucleoprotein
chr3_-_89325594 2.12 ENSMUST00000029679.4
CDC28 protein kinase 1b
chr3_-_107992662 2.10 ENSMUST00000078912.7
adenosine monophosphate deaminase 2
chr9_+_95836869 2.09 ENSMUST00000190665.2
5'-3' exoribonuclease 1
chr11_+_120612369 2.07 ENSMUST00000142229.2
Rac family small GTPase 3
chr14_-_56339915 2.07 ENSMUST00000015583.2
cathepsin G
chr15_+_78294154 2.07 ENSMUST00000229739.2
mercaptopyruvate sulfurtransferase
chr9_+_32607301 2.06 ENSMUST00000034534.13
ENSMUST00000050797.14
ENSMUST00000184887.2
E26 avian leukemia oncogene 1, 5' domain
chr15_-_85462271 2.05 ENSMUST00000229191.2
wingless-type MMTV integration site family, member 7B
chr6_+_124973752 2.05 ENSMUST00000162000.4
PILR alpha associated neural protein
chr18_+_38088597 2.04 ENSMUST00000070709.9
ENSMUST00000177058.8
ENSMUST00000169360.9
ENSMUST00000163591.9
ENSMUST00000091932.12
RELT-like 2
chr9_+_108437485 2.02 ENSMUST00000081111.14
ENSMUST00000193421.2
inosine monophosphate dehydrogenase 2
chr6_-_40413056 2.01 ENSMUST00000039008.10
ENSMUST00000101492.10
DENN domain containing 11
chr5_-_143513732 2.00 ENSMUST00000100489.4
ENSMUST00000080537.14
Rac family small GTPase 1
chr3_+_130906434 1.99 ENSMUST00000098611.4
lymphoid enhancer binding factor 1
chr6_-_91093766 1.98 ENSMUST00000113509.2
ENSMUST00000032179.14
nucleoporin 210
chr1_+_43769750 1.96 ENSMUST00000027217.9
ECRG4 augurin precursor
chr3_+_60408678 1.96 ENSMUST00000191747.6
ENSMUST00000194069.6
muscleblind like splicing factor 1
chr5_-_144160397 1.93 ENSMUST00000085701.7
tectonin beta-propeller repeat containing 1
chr6_+_124973644 1.92 ENSMUST00000032479.11
PILR alpha associated neural protein
chr9_-_31824758 1.91 ENSMUST00000116615.5
BarH-like homeobox 2
chrX_-_73416869 1.87 ENSMUST00000073067.11
ENSMUST00000037967.6
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr16_+_49519561 1.86 ENSMUST00000046777.11
ENSMUST00000142682.9
intraflagellar transport 57
chr2_+_130116357 1.86 ENSMUST00000136621.9
ENSMUST00000141872.2
NOP56 ribonucleoprotein
chr2_-_27032441 1.85 ENSMUST00000151224.3
family with sequence similarity 163, member B
chr14_+_56813060 1.85 ENSMUST00000161553.2
poly (ADP-ribose) polymerase family, member 4
chr11_-_69749549 1.83 ENSMUST00000001626.10
ENSMUST00000108626.8
tyrosine kinase, non-receptor, 1
chr19_-_4665509 1.83 ENSMUST00000053597.3
leucine rich repeat and fibronectin type III domain containing 4
chr11_+_62711057 1.82 ENSMUST00000055006.12
ENSMUST00000072639.10
tripartite motif-containing 16
chr9_-_49479791 1.80 ENSMUST00000194252.6
neural cell adhesion molecule 1
chr2_+_3705824 1.80 ENSMUST00000115054.9
family with sequence similarity 107, member B
chr12_-_46767619 1.78 ENSMUST00000219886.2
NOVA alternative splicing regulator 1
chr14_-_56472102 1.75 ENSMUST00000015585.4
granzyme C
chr11_-_102210568 1.74 ENSMUST00000173870.8
upstream binding transcription factor, RNA polymerase I
chr18_+_68066328 1.68 ENSMUST00000063775.5
low density lipoprotein receptor class A domain containing 4
chr11_-_61384998 1.67 ENSMUST00000101085.9
ENSMUST00000079080.13
ENSMUST00000108714.2
mitogen-activated protein kinase 7
chr4_+_156098292 1.67 ENSMUST00000030952.6
tumor necrosis factor receptor superfamily, member 4
chr2_+_25162487 1.66 ENSMUST00000028341.11
anaphase promoting complex subunit 2
chr4_-_94444975 1.61 ENSMUST00000030313.9
caspase activity and apoptosis inhibitor 1
chr11_+_62711295 1.59 ENSMUST00000108703.2
tripartite motif-containing 16
chr14_-_56499690 1.58 ENSMUST00000015581.6
granzyme B
chr19_-_4665668 1.58 ENSMUST00000113822.3
leucine rich repeat and fibronectin type III domain containing 4
chrX_+_158038778 1.58 ENSMUST00000126686.8
ENSMUST00000033671.13
ribosomal protein S6 kinase polypeptide 3
chr3_+_108191398 1.58 ENSMUST00000135636.6
ENSMUST00000102632.7
sortilin 1
chrX_-_73436293 1.57 ENSMUST00000114138.8
family with sequence similarity 3, member A
chr18_+_75953244 1.55 ENSMUST00000058997.15
zinc finger and BTB domain containing 7C
chr18_-_24736848 1.55 ENSMUST00000070726.10
solute carrier family 39 (metal ion transporter), member 6
chr13_-_55477535 1.54 ENSMUST00000021941.8
Max dimerization protein 3
chr14_-_56812839 1.53 ENSMUST00000225951.2
centromere protein J
chr2_-_25162347 1.49 ENSMUST00000028342.7
SS nuclear autoantigen 1
chr12_-_34956910 1.48 ENSMUST00000239321.2
histone deacetylase 9
chr2_+_28082943 1.46 ENSMUST00000113920.8
olfactomedin 1
chr17_+_87270707 1.44 ENSMUST00000139344.2
ras homolog family member Q
chr11_-_119438569 1.43 ENSMUST00000026670.5
neuronal pentraxin 1
chr16_-_97412169 1.43 ENSMUST00000232141.2
ENSMUST00000000395.8
transmembrane protease, serine 2
chr17_-_57023788 1.43 ENSMUST00000067931.7
vimentin-type intermediate filament associated coiled-coil protein
chr1_+_165957784 1.43 ENSMUST00000060833.14
glycoprotein A33 (transmembrane)
chrX_+_158039107 1.42 ENSMUST00000148570.8
ribosomal protein S6 kinase polypeptide 3
chr15_-_53765869 1.41 ENSMUST00000078673.14
sterile alpha motif domain containing 12
chrX_+_158038915 1.40 ENSMUST00000112492.8
ribosomal protein S6 kinase polypeptide 3
chr2_+_28083105 1.39 ENSMUST00000100244.10
olfactomedin 1
chr4_+_129407374 1.39 ENSMUST00000062356.7
MARCKS-like 1
chr12_+_24622274 1.38 ENSMUST00000085553.13
grainyhead like transcription factor 1
chr10_-_128505096 1.36 ENSMUST00000238610.2
ENSMUST00000238712.2
IKAROS family zinc finger 4
chr10_-_85847697 1.35 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr13_+_45660905 1.35 ENSMUST00000000260.13
guanosine monophosphate reductase
chr15_+_32244947 1.34 ENSMUST00000067458.7
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr4_+_116078874 1.34 ENSMUST00000106490.3
phosphoinositide-3-kinase regulatory subunit 3
chr8_+_84627332 1.34 ENSMUST00000045393.15
ENSMUST00000132500.8
ENSMUST00000152978.8
adhesion G protein-coupled receptor L1
chr5_+_147367237 1.33 ENSMUST00000176600.8
PAN3 poly(A) specific ribonuclease subunit
chr1_-_127605660 1.33 ENSMUST00000160616.8
transmembrane protein 163
chr11_-_97520511 1.32 ENSMUST00000052281.6
elongin BC and polycomb repressive complex 2 associated protein
chr15_+_18819033 1.30 ENSMUST00000166873.9
cadherin 10
chr17_-_37178079 1.29 ENSMUST00000025329.13
ENSMUST00000174195.8
tripartite motif-containing 15
chr16_+_10652910 1.28 ENSMUST00000037913.9
RecQ mediated genome instability 2
chr17_+_8559230 1.28 ENSMUST00000069742.8
proline rich 18
chr9_+_95836839 1.27 ENSMUST00000189106.2
5'-3' exoribonuclease 1
chr9_+_98868418 1.25 ENSMUST00000035038.8
ENSMUST00000112911.9
Fas apoptotic inhibitory molecule
chr8_-_126625029 1.24 ENSMUST00000047239.13
ENSMUST00000131127.3
pecanex homolog 2
chr15_+_79025523 1.23 ENSMUST00000040077.8
polymerase (RNA) II (DNA directed) polypeptide F
chr7_+_48438751 1.22 ENSMUST00000118927.8
ENSMUST00000125280.8
zinc finger, DHHC domain containing 13
chr2_-_92201342 1.21 ENSMUST00000176810.8
ENSMUST00000090582.11
ENSMUST00000068586.13
LARGE xylosyl- and glucuronyltransferase 2
chr19_-_6285827 1.21 ENSMUST00000025695.10
protein phosphatase 2, regulatory subunit B', beta
chr14_-_78545472 1.20 ENSMUST00000022592.8
tumor necrosis factor (ligand) superfamily, member 11
chr18_+_38088179 1.19 ENSMUST00000176902.8
ENSMUST00000176104.8
RELT-like 2
chr8_+_106024294 1.18 ENSMUST00000015003.10
E2F transcription factor 4
chr1_+_130793406 1.18 ENSMUST00000038829.7
Fc fragment of IgM receptor
chr6_+_34453142 1.18 ENSMUST00000045372.6
ENSMUST00000138668.2
ENSMUST00000139067.2
2,3-bisphosphoglycerate mutase
chr7_-_117842787 1.17 ENSMUST00000032891.15
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr2_+_118756973 1.16 ENSMUST00000099546.6
ENSMUST00000110837.2
carbohydrate sulfotransferase 14
chr11_-_94133527 1.16 ENSMUST00000061469.4
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_-_15962881 1.15 ENSMUST00000040695.5
somatomedin B and thrombospondin, type 1 domain containing
chr1_+_165958036 1.14 ENSMUST00000166860.2
glycoprotein A33 (transmembrane)
chr17_-_18075450 1.14 ENSMUST00000003762.8
hyaluronan synthase 1
chr5_-_38719025 1.13 ENSMUST00000005234.13
WD repeat domain 1
chr11_-_120515799 1.13 ENSMUST00000106183.3
ENSMUST00000080202.12
sirtuin 7
chrX_+_9138995 1.12 ENSMUST00000015486.7
X-linked Kx blood group
chr14_-_52481907 1.10 ENSMUST00000226307.2
chromodomain helicase DNA binding protein 8
chr8_+_94879235 1.10 ENSMUST00000034211.10
ENSMUST00000211930.2
ENSMUST00000211915.2
metallothionein 3
chr5_-_74863514 1.09 ENSMUST00000117388.8
ligand of numb-protein X 1
chr15_+_102412157 1.09 ENSMUST00000096145.5
predicted gene 10337
chr11_-_102209767 1.07 ENSMUST00000174302.8
ENSMUST00000178839.8
ENSMUST00000006754.14
upstream binding transcription factor, RNA polymerase I
chr2_-_34716083 1.07 ENSMUST00000113077.8
ENSMUST00000028220.10
F-box and WD-40 domain protein 2
chr4_+_116078830 1.06 ENSMUST00000030464.14
phosphoinositide-3-kinase regulatory subunit 3
chr2_-_156833932 1.06 ENSMUST00000109558.2
ENSMUST00000069600.13
ENSMUST00000072298.13
N-myc downstream regulated gene 3
chrX_-_73436609 1.04 ENSMUST00000015427.13
family with sequence similarity 3, member A
chr11_-_115024807 1.01 ENSMUST00000106561.8
ENSMUST00000051264.14
ENSMUST00000106562.3
CD300 molecule like family member F
chrX_-_73416824 1.01 ENSMUST00000178691.2
ENSMUST00000114146.8
ubiquitin-like 4A
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr5_+_102992873 0.99 ENSMUST00000070000.6
Rho GTPase activating protein 24
chr11_-_48836975 0.99 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr9_-_107474221 0.98 ENSMUST00000238519.2
leucine-rich single-pass membrane protein 2
chr18_+_34353943 0.98 ENSMUST00000171187.8
APC, WNT signaling pathway regulator
chr7_-_119319965 0.97 ENSMUST00000033236.9
THUMP domain containing 1
chr4_+_129878890 0.95 ENSMUST00000106017.8
ENSMUST00000121049.8
adhesion G protein-coupled receptor B2
chr7_-_117842892 0.95 ENSMUST00000179047.3
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr5_+_31107390 0.92 ENSMUST00000006814.9
abhydrolase domain containing 1
chr4_+_62537750 0.92 ENSMUST00000084521.11
ENSMUST00000107424.2
regulator of G-protein signaling 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
2.5 7.6 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
2.4 7.3 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
2.2 11.1 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.9 5.7 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.2 3.5 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0 3.0 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
1.0 3.9 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.9 5.6 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.7 3.5 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.7 3.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 2.5 GO:2001137 protein retention in Golgi apparatus(GO:0045053) positive regulation of endocytic recycling(GO:2001137)
0.6 2.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.6 9.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.6 4.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.6 6.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.6 3.9 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.6 1.7 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.5 1.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.5 2.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.5 1.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.5 2.0 GO:0061153 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.5 5.6 GO:0090503 histone mRNA catabolic process(GO:0071044) RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.5 3.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.5 1.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.4 4.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 4.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 1.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4 3.4 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.4 1.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 6.9 GO:0031268 pseudopodium organization(GO:0031268)
0.3 1.2 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.3 1.8 GO:0061511 centriole elongation(GO:0061511)
0.3 2.9 GO:0032264 IMP salvage(GO:0032264)
0.3 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 4.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.3 1.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.3 2.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.3 1.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 3.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 3.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 1.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.3 2.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.3 2.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 4.8 GO:0006968 cellular defense response(GO:0006968)
0.3 2.3 GO:0043545 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 3.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 2.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 1.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 1.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 2.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 2.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.1 GO:0009092 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.2 2.9 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2 1.4 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.2 1.0 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.2 3.7 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 2.1 GO:0030578 PML body organization(GO:0030578)
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 2.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 6.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 1.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 3.8 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.9 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 5.4 GO:0031424 keratinization(GO:0031424)
0.1 1.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 3.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 4.5 GO:0030033 microvillus assembly(GO:0030033)
0.1 1.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 3.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.9 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.1 1.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.4 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 1.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 5.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.0 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 6.9 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 2.6 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 2.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 8.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 4.3 GO:0001562 response to protozoan(GO:0001562)
0.1 1.4 GO:0002934 desmosome organization(GO:0002934)
0.1 3.3 GO:0006817 phosphate ion transport(GO:0006817)
0.1 4.0 GO:0000154 rRNA modification(GO:0000154)
0.1 0.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 2.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 3.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.9 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 1.9 GO:0001502 cartilage condensation(GO:0001502)
0.1 2.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 1.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 2.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.4 GO:0046039 GTP metabolic process(GO:0046039)
0.0 2.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.4 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 2.3 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 1.2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 4.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0045348 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 2.6 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 6.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.8 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 2.0 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 3.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 4.5 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 1.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 1.3 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747) regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 1.0 GO:0006400 tRNA modification(GO:0006400)
0.0 1.2 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.4 GO:0031523 Myb complex(GO:0031523)
1.2 3.7 GO:1990031 pinceau fiber(GO:1990031)
1.2 9.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.2 6.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.5 2.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.4 1.3 GO:1902560 GMP reductase complex(GO:1902560)
0.4 4.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 7.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 4.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.4 7.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 1.6 GO:0044194 cytolytic granule(GO:0044194)
0.3 1.3 GO:0031251 PAN complex(GO:0031251)
0.3 13.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 5.1 GO:0031143 pseudopodium(GO:0031143)
0.2 2.9 GO:0005642 annulate lamellae(GO:0005642)
0.2 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.3 GO:0070449 elongin complex(GO:0070449)
0.2 0.6 GO:0097361 CIA complex(GO:0097361)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 4.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.4 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 2.4 GO:0005652 integral component of nuclear inner membrane(GO:0005639) nuclear lamina(GO:0005652) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 7.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 8.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 5.4 GO:0001533 cornified envelope(GO:0001533)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0005775 vacuolar lumen(GO:0005775)
0.1 0.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.9 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)
0.1 6.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 6.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 2.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 13.6 GO:0005884 actin filament(GO:0005884)
0.1 3.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 5.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 6.9 GO:0005604 basement membrane(GO:0005604)
0.0 2.5 GO:0001772 immunological synapse(GO:0001772)
0.0 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 5.1 GO:0016605 PML body(GO:0016605)
0.0 5.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0031673 hemidesmosome(GO:0030056) H zone(GO:0031673)
0.0 3.0 GO:0005871 kinesin complex(GO:0005871)
0.0 3.9 GO:0000922 spindle pole(GO:0000922)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 7.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 7.3 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 8.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0005769 early endosome(GO:0005769)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.2 GO:0098793 presynapse(GO:0098793)
0.0 6.4 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.3 7.6 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.2 4.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.1 5.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
1.1 4.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.9 5.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 2.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.7 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.7 3.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.6 6.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.6 2.4 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.5 2.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.5 2.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 1.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 3.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.4 2.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 1.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 4.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 2.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 2.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 7.3 GO:0002162 dystroglycan binding(GO:0002162)
0.3 2.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 2.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 1.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.3 4.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 3.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 1.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 3.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.2 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 4.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 2.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 5.8 GO:0097602 cullin family protein binding(GO:0097602)
0.2 2.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 7.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 2.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 2.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 5.1 GO:0031489 myosin V binding(GO:0031489)
0.2 1.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 5.0 GO:0019956 chemokine binding(GO:0019956)
0.1 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 3.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 5.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 3.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.2 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 14.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 10.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0098640 protein binding involved in cell-matrix adhesion(GO:0098634) integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 5.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 8.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 4.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 5.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 4.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 2.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 4.4 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.4 GO:0015631 tubulin binding(GO:0015631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 2.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 9.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 7.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 9.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 3.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 4.5 PID BMP PATHWAY BMP receptor signaling
0.1 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.1 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 PID FGF PATHWAY FGF signaling pathway
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 6.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 5.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 5.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 4.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 11.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.2 2.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 11.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 2.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 3.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 4.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 3.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.9 REACTOME KINESINS Genes involved in Kinesins
0.1 1.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 3.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 4.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 3.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 5.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes