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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hmx2

Z-value: 0.64

Motif logo

Transcription factors associated with Hmx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000050100.15 Hmx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmx2mm39_v1_chr7_+_131150484_1311505020.325.7e-03Click!

Activity profile of Hmx2 motif

Sorted Z-values of Hmx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_162694076 3.77 ENSMUST00000046049.14
flavin containing monooxygenase 1
chr15_-_74869684 2.73 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
lymphocyte antigen 6 complex, locus A
chr3_-_98767090 2.66 ENSMUST00000107016.10
ENSMUST00000029465.10
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr4_-_147726953 2.59 ENSMUST00000133006.2
ENSMUST00000037565.14
ENSMUST00000105720.8
zinc finger protein 979
chr6_-_24168082 2.46 ENSMUST00000031713.9
solute carrier family 13 (sodium/sulfate symporters), member 1
chr7_+_119206233 2.39 ENSMUST00000126367.8
acyl-CoA synthetase medium-chain family member 1
chr15_-_76906150 2.09 ENSMUST00000230031.2
myoglobin
chr18_+_50184769 2.07 ENSMUST00000134348.8
ENSMUST00000153873.3
tumor necrosis factor, alpha-induced protein 8
chr4_+_94627513 2.06 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chrX_+_163156359 2.00 ENSMUST00000033751.8
vascular endothelial growth factor D
chrX_-_162810959 1.98 ENSMUST00000033739.5
carbonic anhydrase 5b, mitochondrial
chr19_+_12610870 1.84 ENSMUST00000119960.2
glycine-N-acyltransferase
chr19_+_12610668 1.83 ENSMUST00000044976.12
glycine-N-acyltransferase
chrX_+_149377416 1.78 ENSMUST00000112713.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_23938869 1.69 ENSMUST00000114497.2
histamine N-methyltransferase
chr5_+_102916637 1.63 ENSMUST00000112852.8
Rho GTPase activating protein 24
chr18_-_65527078 1.63 ENSMUST00000035548.16
alpha-kinase 2
chr3_+_20011405 1.61 ENSMUST00000108325.9
ceruloplasmin
chr19_-_8382424 1.60 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr2_-_23939401 1.60 ENSMUST00000051416.12
histamine N-methyltransferase
chr8_+_26298502 1.59 ENSMUST00000033979.6
steroidogenic acute regulatory protein
chr9_+_51958453 1.59 ENSMUST00000163153.9
radixin
chrM_+_7758 1.56 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr6_+_48624295 1.55 ENSMUST00000078223.6
ENSMUST00000203509.2
GTPase, IMAP family member 8
chr16_-_56987670 1.53 ENSMUST00000023432.10
nitrilase family, member 2
chr15_-_42540363 1.36 ENSMUST00000022921.7
angiopoietin 1
chr12_-_40249314 1.35 ENSMUST00000095760.3
leucine-rich single-pass membrane protein 1
chrM_+_7779 1.35 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr10_+_128745214 1.31 ENSMUST00000220308.2
CD63 antigen
chr2_-_9883391 1.30 ENSMUST00000102976.4
GATA binding protein 3
chr2_-_17465410 1.28 ENSMUST00000145492.2
nebulette
chr4_+_147576874 1.28 ENSMUST00000105721.9
zinc finger protein 982
chr3_+_20011201 1.27 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr6_-_137146708 1.23 ENSMUST00000117919.8
RAS-like, estrogen-regulated, growth-inhibitor
chr3_+_94280101 1.23 ENSMUST00000029795.10
RAR-related orphan receptor gamma
chr6_-_137146677 1.22 ENSMUST00000119610.4
ENSMUST00000149100.3
RAS-like, estrogen-regulated, growth-inhibitor
chr5_-_53864874 1.21 ENSMUST00000031093.5
cholecystokinin A receptor
chr2_-_127286444 1.21 ENSMUST00000028848.4
fumarylacetoacetate hydrolase domain containing 2A
chr9_+_92339422 1.19 ENSMUST00000034941.9
phospholipid scramblase 4
chr19_-_38031774 1.16 ENSMUST00000226068.2
myoferlin
chr18_-_63520195 1.15 ENSMUST00000047480.13
piezo-type mechanosensitive ion channel component 2
chr4_+_99812912 1.13 ENSMUST00000102783.5
phosphoglucomutase 1
chr2_+_127750978 1.11 ENSMUST00000110344.2
acyl-Coenzyme A oxidase-like
chr4_+_147637714 1.11 ENSMUST00000139784.8
ENSMUST00000143885.8
ENSMUST00000081742.7
zinc finger protein 985
chr11_-_99134885 1.09 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr16_-_95387444 1.08 ENSMUST00000233269.2
ETS transcription factor
chr13_-_63036096 1.06 ENSMUST00000092888.11
fructose bisphosphatase 1
chrX_+_82898974 1.04 ENSMUST00000239269.2
dystrophin, muscular dystrophy
chr1_+_53100796 1.03 ENSMUST00000027269.7
ENSMUST00000191197.2
myostatin
chr11_-_100713348 1.02 ENSMUST00000107358.9
signal transducer and activator of transcription 5B
chr8_-_65489834 1.02 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr10_+_128744689 1.00 ENSMUST00000105229.9
CD63 antigen
chr1_-_172460497 0.99 ENSMUST00000027826.7
dual specificity phosphatase 23
chr1_+_91226076 0.97 ENSMUST00000142488.8
ENSMUST00000124832.8
ENSMUST00000147523.8
selenocysteine lyase
chr13_-_92931317 0.97 ENSMUST00000022213.8
thrombospondin 4
chr11_-_46280281 0.95 ENSMUST00000101306.4
IL2 inducible T cell kinase
chr2_-_45002902 0.95 ENSMUST00000076836.13
ENSMUST00000176732.8
ENSMUST00000200844.4
zinc finger E-box binding homeobox 2
chr5_-_28672091 0.93 ENSMUST00000002708.5
sonic hedgehog
chr2_+_167263626 0.93 ENSMUST00000047815.13
ENSMUST00000109218.7
ENSMUST00000073873.5
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr14_+_73475335 0.93 ENSMUST00000044405.8
lysophosphatidic acid receptor 6
chr2_-_131021905 0.91 ENSMUST00000089510.5
centromere protein B
chr14_+_51333816 0.90 ENSMUST00000169895.3
ribonuclease, RNase A family 4
chr3_-_65299967 0.86 ENSMUST00000119896.2
signal sequence receptor, gamma
chr17_-_34847354 0.85 ENSMUST00000167097.9
palmitoyl-protein thioesterase 2
chr12_+_84498196 0.83 ENSMUST00000137170.3
lin-52 homolog (C. elegans)
chr4_+_33081505 0.77 ENSMUST00000147889.2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr11_-_114939152 0.77 ENSMUST00000092459.4
CD300 molecule like family member D3
chr5_+_8710059 0.77 ENSMUST00000047753.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr6_+_129385893 0.76 ENSMUST00000204860.3
ENSMUST00000164513.8
C-type lectin domain family 9, member a
chr2_+_177409837 0.72 ENSMUST00000108942.5
predicted gene 14322
chr18_+_4993795 0.72 ENSMUST00000153016.8
supervillin
chr14_-_8798841 0.72 ENSMUST00000061045.3
sentan, cilia apical structure protein
chr3_+_108000425 0.71 ENSMUST00000151326.8
guanine nucleotide binding protein, alpha transducing 2
chrX_+_105059305 0.70 ENSMUST00000033582.5
cytochrome c oxidase subunit 7B
chr13_+_23868175 0.70 ENSMUST00000018246.6
H2B clustered histone 4
chr8_+_25507227 0.66 ENSMUST00000033961.7
ENSMUST00000210536.2
TM2 domain containing 2
chr11_-_77971186 0.65 ENSMUST00000021183.4
Era (G-protein)-like 1 (E. coli)
chrX_+_37405054 0.65 ENSMUST00000016471.9
ENSMUST00000115134.2
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
chr7_-_78432774 0.65 ENSMUST00000032841.7
mitochondrial ribosomal protein L46
chr9_-_15212745 0.64 ENSMUST00000217042.2
RIKEN cDNA 4931406C07 gene
chr12_-_98867737 0.61 ENSMUST00000223282.2
echinoderm microtubule associated protein like 5
chr19_-_7943365 0.61 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr7_+_78432867 0.61 ENSMUST00000032840.5
mitochondrial ribosomal protein S11
chrX_-_55643429 0.61 ENSMUST00000059899.3
membrane magnesium transporter 1
chr7_-_30023320 0.59 ENSMUST00000098586.5
succinate dehydrogenase complex assembly factor 1
chr3_-_65300000 0.56 ENSMUST00000029414.12
signal sequence receptor, gamma
chr6_+_40448286 0.54 ENSMUST00000114779.9
single-stranded DNA binding protein 1
chr10_-_19783391 0.54 ENSMUST00000166511.9
ENSMUST00000020182.16
peroxisomal biogenesis factor 7
chr2_-_85917726 0.54 ENSMUST00000216886.2
ENSMUST00000213333.2
ENSMUST00000216020.2
olfactory receptor 1037
chr6_+_40448334 0.53 ENSMUST00000031971.13
single-stranded DNA binding protein 1
chr18_-_88912446 0.53 ENSMUST00000070116.12
ENSMUST00000125362.8
suppressor of cytokine signaling 6
chr19_+_29344846 0.52 ENSMUST00000016640.8
CD274 antigen
chr2_+_85597442 0.51 ENSMUST00000216397.3
olfactory receptor 1013
chr11_-_46280298 0.51 ENSMUST00000109237.9
IL2 inducible T cell kinase
chr19_-_46958001 0.50 ENSMUST00000235234.2
5'-nucleotidase, cytosolic II
chr1_+_91226058 0.49 ENSMUST00000027532.13
selenocysteine lyase
chr10_+_121200984 0.49 ENSMUST00000040344.7
glucosamine (N-acetyl)-6-sulfatase
chr2_-_111324108 0.49 ENSMUST00000208881.2
ENSMUST00000208695.2
ENSMUST00000217611.2
olfactory receptor 1290
chr11_+_58062467 0.48 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr2_-_126342551 0.46 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr2_-_75768752 0.46 ENSMUST00000099996.5
tetratricopeptide repeat domain 30B
chr4_-_132125510 0.44 ENSMUST00000136711.2
ENSMUST00000084249.11
phosphatase and actin regulator 4
chr11_-_114928545 0.44 ENSMUST00000100239.3
CD300 molecule like family member D5
chr11_-_46280336 0.44 ENSMUST00000020664.13
IL2 inducible T cell kinase
chr19_+_29923182 0.43 ENSMUST00000025724.9
interleukin 33
chr14_+_52964069 0.42 ENSMUST00000184883.2
T cell receptor alpha variable 6D-3
chr7_-_10011933 0.41 ENSMUST00000227719.2
ENSMUST00000228622.2
ENSMUST00000228086.2
vomeronasal 1 receptor 66
chr2_-_85632888 0.40 ENSMUST00000217410.3
ENSMUST00000216425.3
olfactory receptor 1016
chr2_+_85835884 0.40 ENSMUST00000111589.3
olfactory receptor 1032
chr8_-_23184070 0.39 ENSMUST00000131767.2
inhibitor of kappaB kinase beta
chr11_-_114917838 0.39 ENSMUST00000100240.3
CD300 molecule like family member D4
chr10_+_58207229 0.38 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr10_-_127147609 0.38 ENSMUST00000037290.12
ENSMUST00000171564.8
methionine-tRNA synthetase 1
chr18_-_34712123 0.37 ENSMUST00000079287.12
NME/NM23 family member 5
chr4_+_147445744 0.37 ENSMUST00000133078.8
ENSMUST00000154154.2
zinc finger protein 978
chr18_-_66155651 0.37 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr9_+_38516398 0.36 ENSMUST00000217057.2
olfactory receptor 914
chr9_-_56151334 0.35 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr17_-_37615204 0.35 ENSMUST00000214376.2
olfactory receptor 101
chr18_-_88912415 0.35 ENSMUST00000145120.3
suppressor of cytokine signaling 6
chr14_-_52728503 0.35 ENSMUST00000073571.6
olfactory receptor 1507
chr2_-_73283010 0.35 ENSMUST00000151939.2
WAS/WASL interacting protein family, member 1
chr7_-_12103200 0.35 ENSMUST00000228653.2
ENSMUST00000227427.2
ENSMUST00000226408.2
vomeronasal 1 receptor 84
chr1_-_120198804 0.34 ENSMUST00000112641.8
STEAP family member 3
chr10_+_69761597 0.34 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
ankyrin 3, epithelial
chr19_-_29344694 0.32 ENSMUST00000138051.2
plasminogen receptor, C-terminal lysine transmembrane protein
chr18_-_32044877 0.31 ENSMUST00000054984.8
SFT2 domain containing 3
chr18_+_37952596 0.30 ENSMUST00000193890.2
ENSMUST00000193941.2
protocadherin gamma subfamily C, 5
chr7_+_139913930 0.29 ENSMUST00000214858.2
olfactory receptor 527
chr2_+_85838122 0.29 ENSMUST00000062166.2
olfactory receptor 1032
chr19_+_13385213 0.29 ENSMUST00000216910.3
olfactory receptor 1469
chr6_-_129362460 0.29 ENSMUST00000032261.9
C-type lectin domain family 12, member B
chr9_+_19533591 0.27 ENSMUST00000215372.2
zinc finger protein 317
chr7_+_89780785 0.27 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr10_-_129627483 0.27 ENSMUST00000091986.4
olfactory receptor 810
chr14_+_51366306 0.25 ENSMUST00000226210.2
ribonuclease, RNase A family, 6
chr9_-_54408780 0.24 ENSMUST00000118600.8
ENSMUST00000118163.8
Dmx-like 2
chr5_+_9163244 0.24 ENSMUST00000198935.2
transmembrane protein 243, mitochondrial
chr11_-_60770098 0.24 ENSMUST00000062677.12
transmembrane protein 11
chr6_+_129022843 0.23 ENSMUST00000032257.10
ENSMUST00000204320.2
killer cell lectin-like receptor subfamily B member 1F
chr11_+_107370375 0.23 ENSMUST00000106750.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr9_+_19533374 0.23 ENSMUST00000213725.2
ENSMUST00000208694.2
zinc finger protein 317
chr8_+_72676649 0.23 ENSMUST00000119003.2
zinc finger protein 617
chr5_-_31684036 0.23 ENSMUST00000202421.2
ENSMUST00000201769.4
ENSMUST00000065388.11
SPT7-like, STAGA complex gamma subunit
chr10_+_129691236 0.23 ENSMUST00000204622.3
olfactory receptor 813
chr14_+_52962756 0.22 ENSMUST00000181483.3
T cell receptor alpha variable 6D-3
chrX_-_9438648 0.22 ENSMUST00000079952.4
H2A histone family member L1O
chr6_+_58239367 0.21 ENSMUST00000226813.2
vomeronasal 1 receptor 28
chr16_+_36755338 0.21 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr15_-_12493574 0.21 ENSMUST00000186113.2
PDZ domain containing 2
chr5_-_28415361 0.21 ENSMUST00000141196.2
canopy FGF signaling regulator 1
chr19_-_12881094 0.21 ENSMUST00000208343.2
ENSMUST00000216989.2
olfactory receptor 1447
chr14_+_48683797 0.21 ENSMUST00000111735.10
transmembrane protein 260
chr9_+_19047613 0.21 ENSMUST00000215699.2
olfactory receptor 837
chr7_-_48145873 0.21 ENSMUST00000186394.2
MAS-related GPR, member X2
chr19_+_41921903 0.20 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr5_-_21156766 0.20 ENSMUST00000036489.10
round spermatid basic protein 1-like
chr8_+_95722289 0.20 ENSMUST00000211984.2
adhesion G protein-coupled receptor G1
chr14_+_26722319 0.20 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr4_+_145241454 0.20 ENSMUST00000105741.2
zinc finger protein 990
chr7_-_107633196 0.20 ENSMUST00000210173.3
olfactory receptor 478
chr7_-_106341650 0.19 ENSMUST00000217734.2
olfactory receptor 697
chr7_+_102834010 0.19 ENSMUST00000106893.3
olfactory receptor 592
chr9_-_39237341 0.19 ENSMUST00000216132.2
olfactory receptor 948
chr6_+_58239022 0.18 ENSMUST00000227805.2
vomeronasal 1 receptor 28
chr7_-_27749453 0.18 ENSMUST00000140053.3
ENSMUST00000032824.10
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr6_-_66614736 0.18 ENSMUST00000074381.6
vomeronasal 1 receptor 34
chr1_+_177557380 0.18 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr4_-_94491473 0.17 ENSMUST00000107107.9
phospholipase A2, activating protein
chr3_-_79053182 0.17 ENSMUST00000118340.7
Rap guanine nucleotide exchange factor (GEF) 2
chr11_-_99241924 0.17 ENSMUST00000017732.3
keratin 27
chr19_+_11674413 0.17 ENSMUST00000069760.13
ENSMUST00000119053.3
oocyte secreted protein 3
chr16_-_58749007 0.17 ENSMUST00000075361.5
ENSMUST00000205668.2
ENSMUST00000205986.4
olfactory receptor 181
chr10_-_129524028 0.16 ENSMUST00000203785.3
ENSMUST00000217576.2
olfactory receptor 802
chr9_-_113537277 0.16 ENSMUST00000111861.4
ENSMUST00000035086.13
programmed cell death 6 interacting protein
chr13_+_38223023 0.16 ENSMUST00000226110.2
RIO kinase 1
chr2_-_86317730 0.15 ENSMUST00000217292.3
olfactory receptor 228
chr2_-_88837317 0.15 ENSMUST00000216271.3
ENSMUST00000214809.3
olfactory receptor 1215
chr13_-_76205115 0.15 ENSMUST00000056130.8
G protein-coupled receptor 150
chr19_+_13674632 0.14 ENSMUST00000214007.2
ENSMUST00000216377.2
ENSMUST00000215493.2
ENSMUST00000216366.2
ENSMUST00000216622.2
olfactory receptor 1491
chr18_-_66072119 0.14 ENSMUST00000025396.5
retina and anterior neural fold homeobox
chr7_-_10803618 0.13 ENSMUST00000165848.10
zinc finger and SCAN domain containing 4, pseudogene 1
chr2_-_88909981 0.13 ENSMUST00000213724.2
olfactory receptor 1219
chr7_+_3648264 0.13 ENSMUST00000206287.2
ENSMUST00000038913.16
CCR4-NOT transcription complex, subunit 3
chr4_-_138601275 0.13 ENSMUST00000105805.2
predicted gene 13030
chr7_+_23754197 0.13 ENSMUST00000086012.5
vomeronasal 1 receptor 183
chr7_+_11464193 0.13 ENSMUST00000226516.2
vomeronasal 1 receptor 73
chr13_-_59705044 0.12 ENSMUST00000165370.9
ENSMUST00000109830.9
ENSMUST00000167096.8
ENSMUST00000022040.14
ENSMUST00000171606.9
ENSMUST00000166585.8
ATP/GTP binding protein 1
chr17_-_37613523 0.12 ENSMUST00000215392.2
olfactory receptor 101
chr6_-_66662890 0.12 ENSMUST00000227749.2
ENSMUST00000227354.2
ENSMUST00000227961.2
ENSMUST00000227346.2
vomeronasal 1 receptor 35
chr4_-_43840201 0.12 ENSMUST00000214281.2
olfactory receptor 157
chr10_+_69761630 0.12 ENSMUST00000182029.8
ankyrin 3, epithelial
chr7_-_23510068 0.12 ENSMUST00000228383.2
vomeronasal 1 receptor 175
chr7_-_12340471 0.12 ENSMUST00000170412.2
vomeronasal 2, receptor 53
chr17_-_20701593 0.12 ENSMUST00000167314.3
ENSMUST00000232850.2
ENSMUST00000233382.2
ENSMUST00000233572.2
ENSMUST00000233830.2
vomeronasal 2, receptor 108
chr14_+_48683581 0.11 ENSMUST00000227440.2
ENSMUST00000124720.8
ENSMUST00000226422.2
ENSMUST00000226400.2
transmembrane protein 260
chr13_+_23191826 0.11 ENSMUST00000228758.2
ENSMUST00000228031.2
ENSMUST00000227573.2
vomeronasal 1 receptor 213
chr7_-_103191924 0.11 ENSMUST00000214269.3
olfactory receptor 612
chr7_-_104983311 0.10 ENSMUST00000211006.3
ENSMUST00000216230.2
olfactory receptor 690
chrY_-_10324589 0.10 ENSMUST00000185576.2
predicted gene, 20834

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.7 3.3 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.3 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 2.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.3 1.0 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.3 1.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 1.6 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 0.9 GO:2000729 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 1.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 1.6 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 1.0 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.3 3.8 GO:0070995 NADPH oxidation(GO:0070995)
0.2 2.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 2.1 GO:0015671 oxygen transport(GO:0015671)
0.2 1.5 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 1.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.2 0.8 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.8 GO:2001025 positive regulation of response to drug(GO:2001025)
0.2 1.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 1.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 1.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 2.2 GO:0015747 urate transport(GO:0015747)
0.1 1.0 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 2.5 GO:0008272 sulfate transport(GO:0008272)
0.1 1.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 3.8 GO:0006825 copper ion transport(GO:0006825)
0.1 1.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.7 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 2.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 2.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.5 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 2.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 2.0 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 3.5 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 2.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.6 GO:0019236 response to pheromone(GO:0019236)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031904 endosome lumen(GO:0031904)
0.6 1.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.6 GO:0051286 cell tip(GO:0051286)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 2.2 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 4.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.5 1.5 GO:0070279 vitamin B6 binding(GO:0070279)
0.4 2.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 2.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.3 0.8 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 2.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.9 GO:0043237 laminin-1 binding(GO:0043237)
0.2 2.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.9 GO:0003696 satellite DNA binding(GO:0003696)
0.2 1.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 3.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 1.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 2.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 2.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 2.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0052851 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 3.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 3.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034) beta-1 adrenergic receptor binding(GO:0031697)
0.0 1.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 1.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.6 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 4.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 5.2 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway