Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Hnf4a

Z-value: 8.01

Motif logo

Transcription factors associated with Hnf4a

Gene Symbol Gene ID Gene Info
ENSMUSG00000017950.17 Hnf4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf4amm39_v1_chr2_+_163389068_1633891080.931.1e-32Click!

Activity profile of Hnf4a motif

Sorted Z-values of Hnf4a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf4a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr14_-_55995912 187.08 ENSMUST00000001497.9
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr3_+_122688721 151.91 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chr2_+_172994841 143.36 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chrX_+_10118544 131.50 ENSMUST00000049910.13
ornithine transcarbamylase
chrX_+_10118600 112.51 ENSMUST00000115528.3
ornithine transcarbamylase
chr19_-_39729431 110.01 ENSMUST00000099472.4
cytochrome P450, family 2, subfamily c, polypeptide 68
chr10_-_128796834 106.31 ENSMUST00000026398.5
methyltransferase like 7B
chr11_+_101258368 102.74 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr15_-_82678490 101.55 ENSMUST00000006094.6
cytochrome P450, family 2, subfamily d, polypeptide 26
chr15_+_98997293 99.29 ENSMUST00000061295.7
DnaJ heat shock protein family (Hsp40) member C22
chr19_-_39801188 91.44 ENSMUST00000162507.2
ENSMUST00000160476.9
ENSMUST00000239028.2
cytochrome P450, family 2, subfamily c, polypeptide 40
chr2_-_25390625 91.21 ENSMUST00000040042.11
complement component 8, gamma polypeptide
chr15_+_82336535 91.02 ENSMUST00000089129.7
ENSMUST00000229313.2
ENSMUST00000231136.2
cytochrome P450, family 2, subfamily d, polypeptide 9
chr3_+_89043879 86.11 ENSMUST00000107482.10
ENSMUST00000127058.2
pyruvate kinase liver and red blood cell
chr3_+_89043440 84.26 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr18_+_21205386 83.43 ENSMUST00000082235.5
meprin 1 beta
chr10_-_25412010 82.74 ENSMUST00000179685.3
small leucine-rich protein 1
chr4_-_62005498 81.02 ENSMUST00000107488.4
ENSMUST00000107472.8
ENSMUST00000084531.11
major urinary protein 3
chr3_+_59939175 80.74 ENSMUST00000029325.5
arylacetamide deacetylase
chr9_+_46151994 80.53 ENSMUST00000034585.7
apolipoprotein A-IV
chr11_-_77784922 80.29 ENSMUST00000017597.5
pipecolic acid oxidase
chr4_+_141473983 79.32 ENSMUST00000038161.5
agmatine ureohydrolase (agmatinase)
chr16_+_37400500 79.01 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr15_+_102058936 78.60 ENSMUST00000023806.14
sterol O-acyltransferase 2
chr16_+_37400590 78.26 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr6_+_71176811 77.37 ENSMUST00000067492.8
fatty acid binding protein 1, liver
chr3_-_10400710 76.86 ENSMUST00000078748.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr19_-_39875192 76.73 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr7_-_135130374 76.00 ENSMUST00000053716.8
clarin 3
chr9_-_46146928 74.46 ENSMUST00000118649.8
apolipoprotein C-III
chr19_-_40062174 74.18 ENSMUST00000048959.5
cytochrome P450, family 2, subfamily c, polypeptide 54
chr1_+_139429430 73.33 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr7_+_44114815 73.26 ENSMUST00000035929.11
ENSMUST00000146128.8
aspartate dehydrogenase domain containing
chr19_+_39275518 72.43 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr5_-_104125270 71.73 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr15_+_10358611 70.71 ENSMUST00000110541.8
ENSMUST00000110542.8
alanine-glyoxylate aminotransferase 2
chr15_-_82648376 70.63 ENSMUST00000055721.6
cytochrome P450, family 2, subfamily d, polypeptide 40
chr5_-_104125192 69.40 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr19_+_12610668 68.86 ENSMUST00000044976.12
glycine-N-acyltransferase
chr19_+_12610870 68.60 ENSMUST00000119960.2
glycine-N-acyltransferase
chr7_-_19410749 68.20 ENSMUST00000003074.16
apolipoprotein C-II
chr1_+_171052623 67.82 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr7_+_119773070 67.65 ENSMUST00000033201.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr19_+_39980868 65.17 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr19_+_44980565 63.99 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_-_10581622 63.89 ENSMUST00000037678.7
triokinase, FMN cyclase
chr19_-_39637489 63.08 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr15_-_82291372 61.71 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr15_+_10358643 61.21 ENSMUST00000022858.8
alanine-glyoxylate aminotransferase 2
chr3_+_118355778 61.20 ENSMUST00000039177.12
dihydropyrimidine dehydrogenase
chr6_-_142418801 60.44 ENSMUST00000032371.8
glycogen synthase 2
chr11_+_115768323 60.17 ENSMUST00000222123.2
myosin XVB
chr5_-_104125226 59.75 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr12_-_103871146 58.74 ENSMUST00000074051.6
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr7_-_105249308 58.39 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr3_+_96737385 58.31 ENSMUST00000058865.14
PDZ domain containing 1
chr19_-_8382424 57.00 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr7_+_44114857 56.27 ENSMUST00000135624.2
aspartate dehydrogenase domain containing
chr17_-_35081456 56.09 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr17_-_43813664 55.78 ENSMUST00000024707.9
ENSMUST00000117137.8
meprin 1 alpha
chr7_+_143027473 54.96 ENSMUST00000052348.12
solute carrier family 22 (organic cation transporter), member 18
chr17_-_35081129 53.84 ENSMUST00000154526.8
complement factor B
chr19_+_38995463 52.15 ENSMUST00000025966.5
cytochrome P450, family 2, subfamily c, polypeptide 55
chr11_-_75330302 51.97 ENSMUST00000043696.9
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr1_+_171041583 51.84 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr2_-_27138347 51.62 ENSMUST00000139312.8
sarcosine dehydrogenase
chr4_-_60697274 51.05 ENSMUST00000117932.2
major urinary protein 12
chr5_-_115109118 50.99 ENSMUST00000031535.12
HNF1 homeobox A
chr11_-_75330415 50.89 ENSMUST00000128330.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr11_+_69945157 50.80 ENSMUST00000108585.9
ENSMUST00000018699.13
asialoglycoprotein receptor 1
chr7_-_25315299 50.13 ENSMUST00000098663.4
ENSMUST00000238895.2
glutamate rich 4
chr6_-_128503666 49.86 ENSMUST00000143664.2
ENSMUST00000112132.8
PZP, alpha-2-macroglobulin like
chr18_-_32170012 49.28 ENSMUST00000134663.2
myosin VIIB
chr1_+_165958036 48.75 ENSMUST00000166860.2
glycoprotein A33 (transmembrane)
chr9_+_44584523 48.59 ENSMUST00000034609.11
ENSMUST00000071219.12
trehalase (brush-border membrane glycoprotein)
chr1_+_165957784 48.10 ENSMUST00000060833.14
glycoprotein A33 (transmembrane)
chr1_+_157353696 47.79 ENSMUST00000111700.8
SEC16 homolog B (S. cerevisiae)
chr16_-_30086317 46.85 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr4_+_118384426 46.56 ENSMUST00000030261.6
RIKEN cDNA 2610528J11 gene
chr4_-_94538329 46.19 ENSMUST00000107101.2
leucine rich repeat containing 19
chr8_-_93956143 45.62 ENSMUST00000176282.2
ENSMUST00000034173.14
carboxylesterase 1E
chr3_+_118355811 45.52 ENSMUST00000149101.3
dihydropyrimidine dehydrogenase
chr15_-_76501525 45.17 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr15_+_3300249 44.68 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr8_+_13087805 44.32 ENSMUST00000128418.8
ENSMUST00000152034.2
coagulation factor X
chr1_+_171041539 43.69 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr4_+_118384183 43.00 ENSMUST00000106367.8
RIKEN cDNA 2610528J11 gene
chrX_-_16683578 42.45 ENSMUST00000040820.13
monoamine oxidase B
chr3_-_121608809 42.30 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr19_-_8109346 41.55 ENSMUST00000065651.5
solute carrier family 22, member 28
chr2_-_119060330 41.17 ENSMUST00000110820.3
protein phosphatase 1, regulatory inhibitor subunit 14D
chr3_-_121608859 41.06 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr2_-_155424576 40.75 ENSMUST00000126322.8
glutathione synthetase
chr5_-_137202790 40.69 ENSMUST00000041226.11
mucin 3, intestinal
chr2_-_119060366 40.63 ENSMUST00000076084.6
protein phosphatase 1, regulatory inhibitor subunit 14D
chr1_+_165957909 40.17 ENSMUST00000166159.2
glycoprotein A33 (transmembrane)
chr1_-_90897329 39.85 ENSMUST00000130042.2
ENSMUST00000027529.12
RAB17, member RAS oncogene family
chr11_+_76795346 39.69 ENSMUST00000072633.4
transmembrane and immunoglobulin domain containing 1
chr8_+_13087292 39.59 ENSMUST00000063820.12
ENSMUST00000033821.11
coagulation factor X
chr9_+_62765362 38.79 ENSMUST00000213643.2
ENSMUST00000034777.14
ENSMUST00000163820.3
ENSMUST00000215870.2
ENSMUST00000214633.2
ENSMUST00000215968.2
calmodulin-like 4
chr17_+_37209002 38.65 ENSMUST00000078438.5
tripartite motif-containing 31
chr7_-_45679703 38.59 ENSMUST00000002850.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr5_+_90708962 38.56 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr9_-_121745354 38.42 ENSMUST00000062474.5
cytochrome P450, family 8, subfamily b, polypeptide 1
chr10_+_75407356 37.87 ENSMUST00000143226.8
ENSMUST00000124259.8
gamma-glutamyltransferase 1
chr1_-_136888118 37.78 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr2_+_58645189 37.66 ENSMUST00000102755.4
ENSMUST00000230627.2
ENSMUST00000229923.2
uridine phosphorylase 2
chr1_+_175459559 37.58 ENSMUST00000040250.15
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr16_+_33614378 36.75 ENSMUST00000115044.8
mucin 13, epithelial transmembrane
chr2_-_110136074 36.70 ENSMUST00000046233.9
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr6_-_125357756 36.55 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr2_-_69172944 36.21 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr16_+_33614715 35.84 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr12_+_59177780 35.72 ENSMUST00000177460.8
MIA SH3 domain ER export factor 2
chr11_+_76795292 35.67 ENSMUST00000142166.8
transmembrane and immunoglobulin domain containing 1
chr9_-_35030479 35.13 ENSMUST00000213526.2
ENSMUST00000215089.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_185187000 35.12 ENSMUST00000061093.7
solute carrier family 30, member 10
chr1_-_87029312 35.01 ENSMUST00000113270.3
alkaline phosphatase, intestinal
chr7_+_30193047 34.25 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chr2_-_13496624 34.04 ENSMUST00000091436.7
cubilin (intrinsic factor-cobalamin receptor)
chr4_+_95467653 33.40 ENSMUST00000043335.11
FGGY carbohydrate kinase domain containing
chr12_+_37291728 33.35 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr10_+_79658392 33.08 ENSMUST00000219305.2
ENSMUST00000046833.5
ENSMUST00000218687.2
mitotic spindle positioning
chr17_-_34822649 32.45 ENSMUST00000015622.8
ring finger protein 5
chr17_-_46749370 32.20 ENSMUST00000087012.7
solute carrier family 22 (organic anion transporter), member 7
chr1_+_87983099 32.17 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr19_-_39451509 32.10 ENSMUST00000035488.3
cytochrome P450, family 2, subfamily c, polypeptide 38
chr15_+_82439273 31.93 ENSMUST00000229103.2
ENSMUST00000068861.8
ENSMUST00000229904.2
cytochrome P450, family 2, subfamily d, polypeptide 12
chr7_+_28533279 31.59 ENSMUST00000208971.2
ENSMUST00000066723.15
lectin, galactose binding, soluble 4
chr1_+_175459735 31.58 ENSMUST00000097458.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr8_-_122671588 31.53 ENSMUST00000057653.8
carbonic anhydrase 5a, mitochondrial
chr12_+_37292029 31.06 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr8_+_13076024 30.75 ENSMUST00000033820.4
coagulation factor VII
chr2_+_58644922 30.65 ENSMUST00000059102.13
uridine phosphorylase 2
chr4_+_95467701 30.31 ENSMUST00000150830.2
ENSMUST00000134012.9
FGGY carbohydrate kinase domain containing
chr11_+_118878999 30.15 ENSMUST00000092373.13
ENSMUST00000106273.3
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr12_+_37291632 29.84 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr1_-_82746169 29.78 ENSMUST00000027331.3
transmembrane 4 L six family member 20
chr11_+_73090270 29.50 ENSMUST00000006105.7
sedoheptulokinase
chr15_-_82278223 29.20 ENSMUST00000170255.2
cytochrome P450, family 2, subfamily d, polypeptide 11
chr19_-_44396092 28.72 ENSMUST00000041331.4
stearoyl-Coenzyme A desaturase 1
chr19_-_44396269 28.29 ENSMUST00000235741.2
stearoyl-Coenzyme A desaturase 1
chr17_+_34596098 28.16 ENSMUST00000080254.7
butyrophilin-like 1
chr6_-_136758716 28.15 ENSMUST00000078095.11
ENSMUST00000032338.10
guanylate cyclase 2c
chr11_+_83741657 27.81 ENSMUST00000021016.10
HNF1 homeobox B
chr8_-_13250535 27.28 ENSMUST00000165605.4
ENSMUST00000209691.2
ENSMUST00000211128.2
ENSMUST00000210317.2
GH regulated TBC protein 1
chr4_+_134124691 26.94 ENSMUST00000105870.8
platelet-activating factor acetylhydrolase 2
chr9_-_44162762 26.70 ENSMUST00000034618.6
PDZ domain containing 3
chr9_-_106035308 26.30 ENSMUST00000159809.2
ENSMUST00000162562.2
ENSMUST00000036382.13
glycerate kinase
chr11_+_83741689 26.22 ENSMUST00000108114.9
HNF1 homeobox B
chr10_+_18720760 26.14 ENSMUST00000019998.9
PERP, TP53 apoptosis effector
chr5_+_31454787 26.07 ENSMUST00000201166.4
ENSMUST00000072228.9
glucokinase regulatory protein
chr2_+_156928962 25.81 ENSMUST00000166140.8
TBC/LysM associated domain containing 2
chr4_-_94538370 25.79 ENSMUST00000053419.9
leucine rich repeat containing 19
chr12_+_111237523 25.09 ENSMUST00000021707.8
amnionless
chr1_+_87983189 24.99 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr11_+_78389913 24.90 ENSMUST00000017488.5
vitronectin
chr4_-_62069046 24.87 ENSMUST00000077719.4
major urinary protein 21
chr19_-_11058452 23.91 ENSMUST00000025636.8
membrane-spanning 4-domains, subfamily A, member 8A
chr10_+_75402090 23.88 ENSMUST00000129232.8
ENSMUST00000143792.8
gamma-glutamyltransferase 1
chr9_-_110818679 23.49 ENSMUST00000084922.6
ENSMUST00000199891.2
receptor transporter protein 3
chr17_-_35100980 23.16 ENSMUST00000152417.8
ENSMUST00000146299.8
complement component 2 (within H-2S)
predicted gene 20547
chr2_-_134396268 22.89 ENSMUST00000028704.3
hydroxyacid oxidase 1, liver
chr3_-_151871867 22.80 ENSMUST00000046614.10
GIPC PDZ domain containing family, member 2
chr11_+_7147779 22.79 ENSMUST00000020704.8
insulin-like growth factor binding protein 1
chr7_+_122813999 22.48 ENSMUST00000131933.8
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr11_-_61157986 22.23 ENSMUST00000066277.10
ENSMUST00000074127.14
ENSMUST00000108715.3
aldehyde dehydrogenase family 3, subfamily A2
chr17_-_46956054 22.19 ENSMUST00000003642.7
kinesin light chain 4
chr9_-_106035332 22.16 ENSMUST00000112543.9
glycerate kinase
chr7_+_122814031 22.15 ENSMUST00000033035.13
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr15_-_89064936 21.95 ENSMUST00000109331.9
plexin B2
chr6_-_85114725 21.94 ENSMUST00000174769.2
ENSMUST00000174286.3
ENSMUST00000045986.8
sepiapterin reductase
chr17_-_37178079 21.90 ENSMUST00000025329.13
ENSMUST00000174195.8
tripartite motif-containing 15
chr5_+_137568982 21.46 ENSMUST00000196471.5
ENSMUST00000198783.5
transferrin receptor 2
chr17_-_46749320 21.29 ENSMUST00000233575.2
solute carrier family 22 (organic anion transporter), member 7
chr15_-_76004395 21.11 ENSMUST00000239552.1
epiplakin 1
chr10_-_128755127 20.89 ENSMUST00000149961.2
ENSMUST00000026406.14
retinol dehydrogenase 5
chr6_-_86742789 20.73 ENSMUST00000123732.4
annexin A4
chr2_-_130480014 20.16 ENSMUST00000089561.10
ENSMUST00000110260.8
leucine zipper, putative tumor suppressor family member 3
chr8_+_3637785 20.10 ENSMUST00000171962.3
ENSMUST00000207712.2
ENSMUST00000207970.2
ENSMUST00000207533.2
ENSMUST00000208240.2
ENSMUST00000207432.2
ENSMUST00000207077.2
calmodulin regulated spectrin-associated protein family, member 3
chr12_+_21366386 19.90 ENSMUST00000076813.8
ENSMUST00000221693.2
ENSMUST00000223345.2
ENSMUST00000222344.2
isoamyl acetate-hydrolyzing esterase 1 homolog
chr13_+_55547498 19.75 ENSMUST00000057167.9
solute carrier family 34 (sodium phosphate), member 1
chr8_-_41469332 19.72 ENSMUST00000131965.2
mitochondrial tumor suppressor 1
chr15_-_82505132 19.54 ENSMUST00000109515.3
cytochrome P450, family 2, subfamily d, polypeptide 34
chr7_-_99344779 19.34 ENSMUST00000137914.2
ENSMUST00000207090.2
ENSMUST00000208225.2
solute carrier organic anion transporter family, member 2b1
chr19_+_39049442 19.03 ENSMUST00000087236.5
cytochrome P450, family 2, subfamily c, polypeptide 65
chr9_-_55419442 18.94 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr5_+_8943943 18.79 ENSMUST00000196067.2
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_-_34962823 18.72 ENSMUST00000069507.9
complement component 4B (Chido blood group)
chr15_-_78739717 18.15 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chr6_+_72333209 17.69 ENSMUST00000206531.2
transmembrane protein 150A
chr11_+_70410009 17.54 ENSMUST00000057685.3
glycolipid transfer protein domain containing 2
chr6_-_86742847 17.54 ENSMUST00000113675.8
annexin A4
chr10_+_127685785 17.36 ENSMUST00000077530.3
retinol dehydrogenase 19
chr8_+_87350672 17.35 ENSMUST00000034141.18
ENSMUST00000122188.10
lon peptidase 2, peroxisomal
chr16_-_17745999 17.15 ENSMUST00000003622.16
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr9_-_110576192 17.04 ENSMUST00000199791.2
parathyroid hormone 1 receptor
chrX_+_95498965 16.61 ENSMUST00000033553.14
hephaestin
chr12_+_59177552 16.13 ENSMUST00000175877.8
MIA SH3 domain ER export factor 2
chr2_+_110427643 15.70 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
81.3 244.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
44.0 131.9 GO:0042853 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853)
35.8 143.4 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
35.6 106.7 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
26.8 80.5 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240)
26.8 80.3 GO:0006553 lysine metabolic process(GO:0006553)
23.8 142.7 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
23.4 116.9 GO:1904970 brush border assembly(GO:1904970)
21.6 129.5 GO:0006742 NADP catabolic process(GO:0006742)
20.8 83.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
20.2 666.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
19.0 57.0 GO:1903699 tarsal gland development(GO:1903699)
18.9 170.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
17.5 157.3 GO:0006572 tyrosine catabolic process(GO:0006572)
17.2 51.6 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
17.0 67.8 GO:0046340 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) diacylglycerol catabolic process(GO:0046340)
13.5 54.0 GO:0061235 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
13.3 39.8 GO:0002414 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
13.2 79.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
12.9 102.9 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
11.8 201.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
11.7 35.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
11.5 69.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
11.4 34.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
10.7 32.1 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
10.6 63.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
10.3 102.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
10.1 80.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
9.9 59.1 GO:0015889 cobalamin transport(GO:0015889)
9.8 29.5 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
9.8 78.6 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
9.7 405.6 GO:0019369 arachidonic acid metabolic process(GO:0019369)
9.5 47.3 GO:0005984 disaccharide metabolic process(GO:0005984)
9.2 64.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
9.2 36.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
9.0 45.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
9.0 9.0 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
8.5 42.5 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
7.8 39.2 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
7.7 61.8 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
7.7 115.8 GO:0015747 urate transport(GO:0015747)
7.5 22.5 GO:0060464 lung lobe formation(GO:0060464) diaphragm morphogenesis(GO:0060540)
7.4 22.2 GO:1903173 sesquiterpenoid metabolic process(GO:0006714) phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
7.3 29.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
7.3 94.3 GO:0046485 ether lipid metabolic process(GO:0046485)
7.2 36.2 GO:0046618 drug export(GO:0046618)
6.6 19.8 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
5.6 134.5 GO:0035634 response to stilbenoid(GO:0035634)
5.6 44.7 GO:0001887 selenium compound metabolic process(GO:0001887)
5.5 225.4 GO:0050892 intestinal absorption(GO:0050892)
5.5 76.4 GO:0019321 pentose metabolic process(GO:0019321)
5.3 58.3 GO:0015879 carnitine transport(GO:0015879)
5.2 26.1 GO:0009750 response to fructose(GO:0009750)
5.1 30.7 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
5.1 51.0 GO:0043691 reverse cholesterol transport(GO:0043691)
4.8 47.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
4.8 57.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
4.7 28.2 GO:0045062 extrathymic T cell selection(GO:0045062)
4.6 22.9 GO:0009441 glycolate metabolic process(GO:0009441)
4.5 9.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
4.5 72.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
4.4 21.9 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
4.3 38.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
4.0 178.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
3.9 23.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
3.8 30.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
3.7 29.7 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
3.7 21.9 GO:1902221 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
3.5 14.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
3.4 17.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
3.3 13.3 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
3.3 22.8 GO:0045218 zonula adherens maintenance(GO:0045218)
3.1 37.8 GO:0061113 pancreas morphogenesis(GO:0061113)
2.9 40.6 GO:1904659 glucose transmembrane transport(GO:1904659)
2.8 14.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
2.8 8.4 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
2.7 26.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
2.5 12.5 GO:0015808 L-alanine transport(GO:0015808)
2.4 40.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
2.3 6.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.2 6.6 GO:0098749 cerebellar neuron development(GO:0098749)
2.1 23.4 GO:0060406 positive regulation of penile erection(GO:0060406)
2.1 24.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
2.0 21.5 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.9 13.1 GO:0015862 uridine transport(GO:0015862)
1.8 32.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.8 18.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
1.8 16.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
1.8 10.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.7 26.1 GO:0002934 desmosome organization(GO:0002934)
1.7 8.6 GO:0090366 DNA cytosine deamination(GO:0070383) positive regulation of mRNA modification(GO:0090366)
1.7 69.0 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
1.7 83.4 GO:1901998 toxin transport(GO:1901998)
1.6 11.5 GO:0000103 sulfate assimilation(GO:0000103)
1.6 30.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.5 191.5 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
1.5 37.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.5 55.0 GO:0015893 drug transport(GO:0015893)
1.4 89.4 GO:0050919 negative chemotaxis(GO:0050919)
1.4 5.7 GO:0061386 closure of optic fissure(GO:0061386)
1.4 4.2 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
1.3 9.0 GO:0001757 somite specification(GO:0001757)
1.3 8.9 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
1.3 26.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.2 35.2 GO:0006491 N-glycan processing(GO:0006491)
1.2 11.6 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
1.1 2.2 GO:0006824 cobalt ion transport(GO:0006824)
1.1 5.3 GO:0097459 iron ion import into cell(GO:0097459) iron ion import across plasma membrane(GO:0098711)
1.0 60.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.0 7.8 GO:0007403 glial cell fate determination(GO:0007403)
1.0 8.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.9 19.7 GO:0034389 lipid particle organization(GO:0034389)
0.9 23.5 GO:0051205 protein insertion into membrane(GO:0051205)
0.9 7.8 GO:0030035 microspike assembly(GO:0030035)
0.8 72.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.8 25.8 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.7 3.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.7 49.9 GO:0007566 embryo implantation(GO:0007566)
0.7 2.8 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 3.9 GO:0090168 Golgi reassembly(GO:0090168)
0.7 28.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.6 5.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.6 13.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.6 19.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.6 63.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.6 10.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.6 3.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.6 68.3 GO:0009166 nucleotide catabolic process(GO:0009166)
0.5 14.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.5 31.5 GO:0006094 gluconeogenesis(GO:0006094)
0.5 5.3 GO:0070814 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.5 17.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.5 5.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 86.8 GO:0009636 response to toxic substance(GO:0009636)
0.5 6.7 GO:0042574 retinal metabolic process(GO:0042574)
0.5 2.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 78.3 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.4 9.0 GO:0006825 copper ion transport(GO:0006825)
0.4 7.1 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.4 4.9 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.4 20.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.3 10.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.3 27.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 3.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 4.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 3.4 GO:0022615 protein to membrane docking(GO:0022615)
0.3 79.3 GO:0006814 sodium ion transport(GO:0006814)
0.3 57.7 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.3 50.8 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.2 1.3 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.2 1.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 4.9 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.2 42.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 6.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 4.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 59.2 GO:0032259 methylation(GO:0032259)
0.1 1.2 GO:0016559 peroxisome fission(GO:0016559)
0.1 19.9 GO:0006956 complement activation(GO:0006956)
0.1 0.8 GO:0019243 methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 27.7 GO:0016311 dephosphorylation(GO:0016311)
0.1 10.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 11.2 GO:0045861 negative regulation of proteolysis(GO:0045861)
0.1 3.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 15.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 6.7 GO:0035264 multicellular organism growth(GO:0035264)
0.0 2.0 GO:0007596 blood coagulation(GO:0007596)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
20.8 229.3 GO:0045179 apical cortex(GO:0045179)
14.0 210.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
11.4 102.9 GO:0005577 fibrinogen complex(GO:0005577)
10.1 91.2 GO:0005579 membrane attack complex(GO:0005579)
7.0 35.2 GO:0017177 glucosidase II complex(GO:0017177)
6.8 34.0 GO:0043202 lysosomal lumen(GO:0043202)
6.7 26.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
6.2 68.3 GO:0045098 type III intermediate filament(GO:0045098)
4.7 80.5 GO:0042627 chylomicron(GO:0042627)
3.8 68.3 GO:0046581 intercellular canaliculus(GO:0046581)
3.6 407.7 GO:0005811 lipid particle(GO:0005811)
3.6 24.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
3.5 101.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.2 22.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
2.0 69.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
2.0 32.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.8 54.4 GO:0031528 microvillus membrane(GO:0031528)
1.7 13.5 GO:0008091 spectrin(GO:0008091)
1.7 21.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.6 190.5 GO:0005902 microvillus(GO:0005902)
1.5 20.1 GO:0036449 microtubule minus-end(GO:0036449)
1.5 10.5 GO:0070695 FHF complex(GO:0070695)
1.4 60.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
1.4 51.0 GO:0045120 pronucleus(GO:0045120)
1.3 9.0 GO:1990357 terminal web(GO:1990357)
1.2 250.6 GO:0005903 brush border(GO:0005903)
1.2 28.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.0 29.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.9 342.5 GO:0016324 apical plasma membrane(GO:0016324)
0.9 235.1 GO:0072562 blood microparticle(GO:0072562)
0.8 143.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.8 5.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.6 311.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.5 1053.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.5 83.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.5 40.7 GO:0005871 kinesin complex(GO:0005871)
0.5 11.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.4 35.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.4 1093.6 GO:0070062 extracellular exosome(GO:0070062)
0.3 31.3 GO:0055037 recycling endosome(GO:0055037)
0.3 54.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 38.1 GO:0009986 cell surface(GO:0009986)
0.2 20.2 GO:0043197 dendritic spine(GO:0043197)
0.2 266.5 GO:0005739 mitochondrion(GO:0005739)
0.2 214.6 GO:0005615 extracellular space(GO:0005615)
0.2 16.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 118.4 GO:0005576 extracellular region(GO:0005576)
0.1 66.7 GO:0005768 endosome(GO:0005768)
0.1 7.8 GO:0030175 filopodium(GO:0030175)
0.1 3.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 6.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 111.3 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.1 2.4 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 127.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 6.9 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
61.0 244.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
47.8 143.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
35.6 106.7 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
35.6 142.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
34.7 312.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
34.4 137.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
34.1 170.4 GO:0004743 pyruvate kinase activity(GO:0004743)
31.6 126.3 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
31.4 94.3 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
25.7 102.7 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
22.3 133.6 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
22.0 131.9 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
21.3 63.9 GO:0004371 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
21.2 63.7 GO:0019150 D-ribulokinase activity(GO:0019150)
20.1 60.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
17.2 51.6 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
17.1 68.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
16.3 440.1 GO:0070330 aromatase activity(GO:0070330)
13.4 80.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
13.4 80.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
12.5 249.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
11.4 68.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
11.3 45.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
9.7 29.2 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
9.7 58.4 GO:0015232 heme transporter activity(GO:0015232)
9.6 76.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
9.5 57.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
7.8 23.4 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
7.3 95.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
7.3 58.3 GO:0005124 scavenger receptor binding(GO:0005124)
7.2 79.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
6.8 115.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
6.3 69.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
5.9 172.0 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
5.5 160.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
5.5 49.7 GO:0016936 galactoside binding(GO:0016936)
5.3 32.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
5.1 61.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
5.1 91.2 GO:0019841 retinol binding(GO:0019841)
5.0 75.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
5.0 35.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
5.0 35.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
4.9 34.0 GO:0030492 hemoglobin binding(GO:0030492)
4.7 14.1 GO:0047223 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
4.7 164.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
4.4 13.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
4.4 30.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
4.3 17.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
4.3 21.5 GO:0004998 transferrin receptor activity(GO:0004998)
4.2 12.5 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
4.0 19.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.8 80.7 GO:0004806 triglyceride lipase activity(GO:0004806)
3.8 49.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
3.8 26.7 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
3.5 14.1 GO:0031708 endothelin B receptor binding(GO:0031708)
3.4 17.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
3.4 40.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
3.3 46.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
3.0 30.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
2.7 29.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
2.7 10.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.6 23.5 GO:0031849 olfactory receptor binding(GO:0031849)
2.6 26.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
2.5 44.7 GO:0008430 selenium binding(GO:0008430)
2.3 18.7 GO:0001849 complement component C1q binding(GO:0001849)
2.3 55.0 GO:0015238 drug transmembrane transporter activity(GO:0015238)
2.3 22.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
2.3 9.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
2.2 53.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
2.2 8.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
2.0 82.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.9 26.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
1.9 7.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.9 40.8 GO:0016594 glycine binding(GO:0016594)
1.8 32.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.8 5.3 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
1.7 15.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.7 38.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.7 5.2 GO:0042602 riboflavin reductase (NADPH) activity(GO:0042602)
1.7 8.6 GO:0004131 cytosine deaminase activity(GO:0004131)
1.7 22.0 GO:0017154 semaphorin receptor activity(GO:0017154)
1.7 24.8 GO:0051525 NFAT protein binding(GO:0051525)
1.6 55.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.6 11.5 GO:0050294 alcohol sulfotransferase activity(GO:0004027) steroid sulfotransferase activity(GO:0050294)
1.6 87.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.5 28.2 GO:0015643 toxic substance binding(GO:0015643)
1.5 11.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.4 57.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.4 16.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.3 25.4 GO:0038191 neuropilin binding(GO:0038191)
1.3 34.2 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
1.3 22.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.1 138.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.1 247.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.0 20.1 GO:0051011 microtubule minus-end binding(GO:0051011)
1.0 7.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.9 71.8 GO:0038024 cargo receptor activity(GO:0038024)
0.9 141.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.8 8.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.8 38.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.7 51.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.7 3.5 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.7 6.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 6.2 GO:0051434 BH3 domain binding(GO:0051434)
0.6 4.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.5 37.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.5 62.4 GO:0005550 pheromone binding(GO:0005550)
0.5 72.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.5 2.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 36.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.5 36.6 GO:0019003 GDP binding(GO:0019003)
0.5 5.9 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.4 5.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 6.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 12.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.4 47.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.4 40.7 GO:0003777 microtubule motor activity(GO:0003777)
0.3 54.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 1.9 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 6.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 38.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.3 18.9 GO:0009055 electron carrier activity(GO:0009055)
0.3 74.4 GO:0008168 methyltransferase activity(GO:0008168)
0.3 4.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 158.9 GO:0016491 oxidoreductase activity(GO:0016491)
0.2 19.6 GO:0003774 motor activity(GO:0003774)
0.2 16.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 9.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 4.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 16.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 27.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 5.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 20.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 3.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 3.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 2.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 3.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 53.7 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 4.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 544.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
3.6 98.3 ST G ALPHA S PATHWAY G alpha s Pathway
1.6 452.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.6 326.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.1 24.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8 42.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.7 91.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.6 20.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 26.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 29.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 22.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 22.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 14.1 PID ENDOTHELIN PATHWAY Endothelins
0.2 18.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 7.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 6.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
15.3 306.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
12.1 48.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
9.9 197.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
9.8 157.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
9.5 133.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
9.0 143.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
8.3 108.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
6.3 221.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
5.4 91.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
4.9 69.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
4.6 91.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
4.4 79.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
3.6 36.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
3.4 30.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
3.2 67.8 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
3.0 39.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
3.0 38.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.8 72.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
2.6 251.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
2.2 35.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
2.1 119.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
1.9 432.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
1.8 47.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.6 67.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.3 22.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.3 23.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
1.2 29.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
1.2 21.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.1 16.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.1 22.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.1 18.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.0 95.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.9 84.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.8 94.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.8 42.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.8 30.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.8 102.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.7 30.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.7 22.2 REACTOME KINESINS Genes involved in Kinesins
0.6 44.6 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.5 9.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.5 14.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 6.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 3.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 19.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 13.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 13.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 12.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 19.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 27.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 13.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation