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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxa1

Z-value: 1.10

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Transcription factors associated with Hoxa1

Gene Symbol Gene ID Gene Info
Hoxa1
ENSMUSG00000029844.10 Hoxa1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa1mm39_v1_chr6_-_52135261_521353320.075.8e-01Click!

Activity profile of Hoxa1 motif

Sorted Z-values of Hoxa1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_158217558 22.06 ENSMUST00000109488.8
Snhg11
small nucleolar RNA host gene 11
chr15_-_95426419 14.25 ENSMUST00000229933.2
ENSMUST00000166170.9
Nell2
NEL-like 2
chr4_-_143026068 11.90 ENSMUST00000030317.14
Pdpn
podoplanin
chr15_+_82136598 11.44 ENSMUST00000136948.3
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr13_-_12355604 10.18 ENSMUST00000168193.8
ENSMUST00000064204.14
Actn2
actinin alpha 2
chr10_+_81464370 9.31 ENSMUST00000123896.8
ENSMUST00000153573.2
ENSMUST00000119336.8
Ankrd24
ankyrin repeat domain 24
chr11_-_99134885 7.91 ENSMUST00000103132.10
ENSMUST00000038214.7
Krt222
keratin 222
chr17_+_70829050 7.51 ENSMUST00000133717.9
ENSMUST00000148486.8
Dlgap1
DLG associated protein 1
chr3_-_88669551 7.39 ENSMUST00000183267.2
Syt11
synaptotagmin XI
chr17_+_26036893 7.27 ENSMUST00000235694.2
Fbxl16
F-box and leucine-rich repeat protein 16
chr14_+_66581818 6.70 ENSMUST00000118426.8
ENSMUST00000121955.8
ENSMUST00000120229.8
ENSMUST00000134440.2
Stmn4
stathmin-like 4
chr10_-_33500583 6.52 ENSMUST00000161692.2
ENSMUST00000160299.2
ENSMUST00000019920.13
Clvs2
clavesin 2
chr17_+_70829144 6.38 ENSMUST00000140728.8
Dlgap1
DLG associated protein 1
chr7_+_73040908 6.31 ENSMUST00000128471.2
ENSMUST00000139780.3
Rgma
repulsive guidance molecule family member A
chr14_+_70314727 6.31 ENSMUST00000225200.2
Egr3
early growth response 3
chr5_+_27466914 6.30 ENSMUST00000101471.4
Dpp6
dipeptidylpeptidase 6
chr10_+_81068980 6.30 ENSMUST00000144087.2
ENSMUST00000117798.8
Zfr2
zinc finger RNA binding protein 2
chr14_+_66581745 6.28 ENSMUST00000152093.8
ENSMUST00000074523.13
Stmn4
stathmin-like 4
chr17_-_90763300 6.19 ENSMUST00000159778.8
ENSMUST00000174337.8
ENSMUST00000172466.8
Nrxn1
neurexin I
chr14_+_70314652 5.56 ENSMUST00000035908.3
Egr3
early growth response 3
chr2_-_130885008 5.54 ENSMUST00000110240.10
ENSMUST00000066958.11
ENSMUST00000110235.2
Gfra4
glial cell line derived neurotrophic factor family receptor alpha 4
chr9_+_15150341 5.37 ENSMUST00000034413.8
Vstm5
V-set and transmembrane domain containing 5
chr15_+_74388044 5.29 ENSMUST00000042035.16
Adgrb1
adhesion G protein-coupled receptor B1
chr5_+_137059127 5.24 ENSMUST00000041543.9
ENSMUST00000186451.2
Vgf
VGF nerve growth factor inducible
chr2_+_165436929 5.11 ENSMUST00000088132.13
Eya2
EYA transcriptional coactivator and phosphatase 2
chr14_-_104081827 5.10 ENSMUST00000022718.11
Ednrb
endothelin receptor type B
chr8_+_12999480 5.05 ENSMUST00000110866.9
Mcf2l
mcf.2 transforming sequence-like
chr8_+_12999394 4.86 ENSMUST00000110867.9
Mcf2l
mcf.2 transforming sequence-like
chr5_+_24679154 4.79 ENSMUST00000199856.2
Agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_-_130884602 4.72 ENSMUST00000028787.12
ENSMUST00000110239.8
ENSMUST00000110234.8
Gfra4
glial cell line derived neurotrophic factor family receptor alpha 4
chr2_+_65676111 4.71 ENSMUST00000122912.8
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_-_4796217 4.71 ENSMUST00000027020.13
ENSMUST00000163309.2
Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
chr4_+_101365144 4.56 ENSMUST00000149047.8
ENSMUST00000106929.10
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr19_+_45036037 4.54 ENSMUST00000062213.13
Sfxn3
sideroflexin 3
chr19_+_45036220 4.45 ENSMUST00000084493.8
Sfxn3
sideroflexin 3
chr2_+_90716204 4.44 ENSMUST00000111466.3
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr2_+_156317416 4.44 ENSMUST00000029155.16
Epb41l1
erythrocyte membrane protein band 4.1 like 1
chr19_+_45035942 4.26 ENSMUST00000237222.2
ENSMUST00000111954.11
Sfxn3
sideroflexin 3
chr3_+_68479578 4.18 ENSMUST00000170788.9
Schip1
schwannomin interacting protein 1
chr4_-_106656976 4.00 ENSMUST00000145061.8
ENSMUST00000102762.10
Acot11
acyl-CoA thioesterase 11
chr5_+_88731366 3.94 ENSMUST00000199312.5
Rufy3
RUN and FYVE domain containing 3
chr4_+_101365052 3.93 ENSMUST00000038207.12
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr5_+_88731386 3.85 ENSMUST00000031229.11
Rufy3
RUN and FYVE domain containing 3
chr1_+_11063678 3.68 ENSMUST00000027056.12
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr1_+_153541020 3.64 ENSMUST00000152114.8
ENSMUST00000111812.8
Rgs8
regulator of G-protein signaling 8
chr4_-_143026033 3.61 ENSMUST00000119654.2
Pdpn
podoplanin
chr9_-_4796142 3.60 ENSMUST00000063508.15
Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
chr2_+_65676176 3.55 ENSMUST00000053910.10
Csrnp3
cysteine-serine-rich nuclear protein 3
chr3_-_89000591 3.43 ENSMUST00000090929.12
ENSMUST00000052539.13
Rusc1
RUN and SH3 domain containing 1
chr10_+_94412116 3.41 ENSMUST00000117929.2
Tmcc3
transmembrane and coiled coil domains 3
chr4_+_43669266 3.29 ENSMUST00000107864.8
Tmem8b
transmembrane protein 8B
chr19_-_41732104 2.83 ENSMUST00000025993.10
Slit1
slit guidance ligand 1
chr5_+_137059522 2.79 ENSMUST00000187382.2
Vgf
VGF nerve growth factor inducible
chr1_+_85822250 2.66 ENSMUST00000185569.2
Itm2c
integral membrane protein 2C
chr6_-_136852792 2.59 ENSMUST00000032342.3
Mgp
matrix Gla protein
chrX_+_55500170 2.51 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
Ints6l
integrator complex subunit 6 like
chr11_-_118460736 2.49 ENSMUST00000136551.3
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr6_+_40302106 2.44 ENSMUST00000031977.12
Agk
acylglycerol kinase
chr17_-_25300112 2.28 ENSMUST00000024984.7
Tmem204
transmembrane protein 204
chr17_-_28841006 2.10 ENSMUST00000233353.2
Srpk1
serine/arginine-rich protein specific kinase 1
chr3_-_79053182 2.09 ENSMUST00000118340.7
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_+_119803230 2.05 ENSMUST00000229024.2
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr3_-_57202546 2.02 ENSMUST00000196506.2
Tm4sf1
transmembrane 4 superfamily member 1
chrX_+_109857866 1.97 ENSMUST00000078229.5
Pou3f4
POU domain, class 3, transcription factor 4
chr2_+_32477069 1.93 ENSMUST00000102818.11
St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr4_-_106657446 1.90 ENSMUST00000148688.2
Acot11
acyl-CoA thioesterase 11
chr8_-_91544021 1.79 ENSMUST00000209208.2
Gm19935
predicted gene, 19935
chr9_+_121727421 1.75 ENSMUST00000214340.2
ENSMUST00000050327.5
Ackr2
atypical chemokine receptor 2
chr3_+_113824181 1.62 ENSMUST00000123619.8
ENSMUST00000092155.12
Col11a1
collagen, type XI, alpha 1
chr17_-_28841370 1.62 ENSMUST00000233129.2
ENSMUST00000232751.2
ENSMUST00000233794.2
ENSMUST00000114767.3
Srpk1
serine/arginine-rich protein specific kinase 1
chr7_-_144024451 1.59 ENSMUST00000033407.13
Cttn
cortactin
chr16_+_16714333 1.49 ENSMUST00000027373.12
ENSMUST00000232247.2
Ppm1f
protein phosphatase 1F (PP2C domain containing)
chr16_+_38722666 1.40 ENSMUST00000023478.8
Igsf11
immunoglobulin superfamily, member 11
chr16_-_10360893 1.39 ENSMUST00000184863.8
ENSMUST00000038281.6
Dexi
dexamethasone-induced transcript
chr11_+_24030663 1.33 ENSMUST00000118955.2
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr4_-_108263873 1.32 ENSMUST00000184609.2
Gpx7
glutathione peroxidase 7
chr7_-_102507962 1.30 ENSMUST00000213481.2
ENSMUST00000209952.2
Olfr566
olfactory receptor 566
chr9_+_110173253 1.27 ENSMUST00000199709.3
Scap
SREBF chaperone
chr2_+_111136546 1.25 ENSMUST00000090329.2
Olfr1279
olfactory receptor 1279
chr15_+_89095724 1.20 ENSMUST00000227951.2
ENSMUST00000226221.2
ENSMUST00000238818.2
ENSMUST00000228284.2
Ppp6r2
protein phosphatase 6, regulatory subunit 2
chrX_-_7999009 1.15 ENSMUST00000130832.8
ENSMUST00000033506.13
ENSMUST00000115623.8
ENSMUST00000153839.2
Wdr13
WD repeat domain 13
chr12_-_80306865 1.11 ENSMUST00000167327.2
Actn1
actinin, alpha 1
chr1_-_43866910 1.10 ENSMUST00000153317.6
ENSMUST00000128261.2
ENSMUST00000126008.8
ENSMUST00000139451.8
Uxs1
UDP-glucuronate decarboxylase 1
chr11_-_40646090 1.06 ENSMUST00000020576.8
Ccng1
cyclin G1
chr3_-_152931392 0.98 ENSMUST00000199707.2
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr2_-_63014622 0.87 ENSMUST00000075052.10
ENSMUST00000112454.8
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_+_119803180 0.81 ENSMUST00000066058.8
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr15_+_9140614 0.81 ENSMUST00000227556.3
Lmbrd2
LMBR1 domain containing 2
chr11_-_5848771 0.81 ENSMUST00000102921.4
Myl7
myosin, light polypeptide 7, regulatory
chr5_+_125518609 0.79 ENSMUST00000049040.14
Bri3bp
Bri3 binding protein
chr16_+_22926162 0.78 ENSMUST00000023599.13
ENSMUST00000168891.8
Eif4a2
eukaryotic translation initiation factor 4A2
chr18_+_56695515 0.71 ENSMUST00000130163.8
ENSMUST00000132628.8
Phax
phosphorylated adaptor for RNA export
chr7_-_103320398 0.71 ENSMUST00000062144.4
Olfr624
olfactory receptor 624
chr4_+_128582519 0.66 ENSMUST00000106080.8
Phc2
polyhomeotic 2
chr3_+_58433236 0.58 ENSMUST00000029387.15
Eif2a
eukaryotic translation initiation factor 2A
chr9_+_58036345 0.56 ENSMUST00000085677.9
Stra6
stimulated by retinoic acid gene 6
chr7_+_141048191 0.54 ENSMUST00000211071.2
Cd151
CD151 antigen
chr9_+_59496571 0.54 ENSMUST00000121266.8
ENSMUST00000118164.3
Celf6
CUGBP, Elav-like family member 6
chr2_-_152793469 0.50 ENSMUST00000037715.7
Dusp15
dual specificity phosphatase-like 15
chr10_+_73782857 0.49 ENSMUST00000191709.6
ENSMUST00000193739.6
ENSMUST00000195531.6
Pcdh15
protocadherin 15
chr3_+_55689921 0.48 ENSMUST00000075422.6
Mab21l1
mab-21-like 1
chr3_+_58913234 0.48 ENSMUST00000040846.15
Med12l
mediator complex subunit 12-like
chr7_+_106513407 0.44 ENSMUST00000098140.2
Olfr1532-ps1
olfactory receptor 1532, pseudogene 1
chr2_-_104324035 0.42 ENSMUST00000111124.8
Hipk3
homeodomain interacting protein kinase 3
chr4_-_35845204 0.41 ENSMUST00000164772.8
ENSMUST00000065173.9
Lingo2
leucine rich repeat and Ig domain containing 2
chr4_-_148021159 0.34 ENSMUST00000105712.2
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr5_-_138981842 0.33 ENSMUST00000110897.8
Pdgfa
platelet derived growth factor, alpha
chrX_-_133062677 0.32 ENSMUST00000033611.5
Xkrx
X-linked Kx blood group related, X-linked
chr5_+_43672856 0.28 ENSMUST00000076939.10
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr11_-_102187445 0.28 ENSMUST00000107132.3
ENSMUST00000073234.9
Atxn7l3
ataxin 7-like 3
chr11_+_103664976 0.27 ENSMUST00000000127.6
Wnt3
wingless-type MMTV integration site family, member 3
chr18_-_56695333 0.24 ENSMUST00000066208.13
ENSMUST00000172734.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr11_+_4833186 0.22 ENSMUST00000139737.2
Nipsnap1
nipsnap homolog 1
chr16_-_18695267 0.20 ENSMUST00000119273.2
Mrpl40
mitochondrial ribosomal protein L40
chr2_-_165717697 0.18 ENSMUST00000153655.8
Zmynd8
zinc finger, MYND-type containing 8
chr13_+_113429690 0.15 ENSMUST00000136755.10
Cspg4b
chondroitin sulfate proteoglycan 4B
chr1_+_74700952 0.10 ENSMUST00000129890.8
Ttll4
tubulin tyrosine ligase-like family, member 4
chr3_-_126918491 0.08 ENSMUST00000238781.2
Ank2
ankyrin 2, brain
chr1_-_157240138 0.07 ENSMUST00000078308.13
Rasal2
RAS protein activator like 2
chr7_+_103628383 0.06 ENSMUST00000098185.2
Olfr635
olfactory receptor 635
chr9_+_58036604 0.00 ENSMUST00000034880.10
Stra6
stimulated by retinoic acid gene 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
3.4 10.2 GO:0086097 actin filament uncapping(GO:0051695) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.8 7.4 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
1.4 8.5 GO:0072318 clathrin coat disassembly(GO:0072318)
1.1 13.9 GO:0070842 aggresome assembly(GO:0070842)
1.0 2.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.0 6.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.9 5.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.8 14.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.8 11.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.5 8.0 GO:0043084 penile erection(GO:0043084)
0.5 2.8 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.4 6.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 4.8 GO:0030578 PML body organization(GO:0030578)
0.4 2.9 GO:0007256 activation of JNKK activity(GO:0007256) negative regulation of defense response to bacterium(GO:1900425)
0.3 2.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 1.3 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.3 6.3 GO:1900121 negative regulation of axon regeneration(GO:0048681) negative regulation of receptor binding(GO:1900121)
0.2 7.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 3.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 0.7 GO:0051030 snRNA transport(GO:0051030)
0.2 4.2 GO:0001553 luteinization(GO:0001553)
0.2 9.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 8.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 13.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.6 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.3 GO:0035789 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 2.0 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 6.4 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:1904954 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 4.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 6.5 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 10.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 3.7 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 8.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 2.3 GO:0001945 lymph vessel development(GO:0001945)
0.1 7.4 GO:0055072 iron ion homeostasis(GO:0055072)
0.1 3.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.6 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.3 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 5.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 4.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 3.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 15.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.0 8.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 7.4 GO:0032009 early phagosome(GO:0032009)
0.3 7.8 GO:0071437 invadopodium(GO:0071437)
0.3 6.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 10.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.1 1.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 3.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 16.7 GO:0043204 perikaryon(GO:0043204)
0.1 8.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 7.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 16.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 33.5 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 7.3 GO:0005882 intermediate filament(GO:0005882)
0.1 6.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 9.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 5.2 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 6.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 4.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 8.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 13.1 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
2.0 10.2 GO:0051373 FATZ binding(GO:0051373)
1.7 5.1 GO:0004962 endothelin receptor activity(GO:0004962)
1.0 8.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.8 2.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.7 15.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.5 2.8 GO:0048495 Roundabout binding(GO:0048495)
0.5 6.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.4 6.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 2.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.3 9.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 2.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 8.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 5.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 6.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 14.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 7.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 3.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 13.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 6.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 4.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.1 3.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 13.1 GO:0015631 tubulin binding(GO:0015631)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 8.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 13.8 GO:0019904 protein domain specific binding(GO:0019904)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 11.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 13.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 6.3 PID BMP PATHWAY BMP receptor signaling
0.1 4.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 19.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 5.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 18.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 6.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 4.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 9.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 6.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 4.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA