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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxa7_Hoxc8

Z-value: 0.82

Motif logo

Transcription factors associated with Hoxa7_Hoxc8

Gene Symbol Gene ID Gene Info
ENSMUSG00000038236.9 Hoxa7
ENSMUSG00000001657.8 Hoxc8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc8mm39_v1_chr15_+_102898966_1028990390.397.6e-04Click!
Hoxa7mm39_v1_chr6_-_52194414_521944320.171.6e-01Click!

Activity profile of Hoxa7_Hoxc8 motif

Sorted Z-values of Hoxa7_Hoxc8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa7_Hoxc8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_96295011 11.75 ENSMUST00000233816.2
Purkinje cell protein 4
chr15_-_8740218 10.52 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8739893 9.64 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_+_34078333 8.33 ENSMUST00000025685.8
lipase, family member M
chr15_-_37458768 6.71 ENSMUST00000116445.9
neurocalcin delta
chr10_+_29074950 5.18 ENSMUST00000217011.2
predicted gene, 49353
chrX_+_9751861 5.18 ENSMUST00000067529.9
ENSMUST00000086165.4
synaptotagmin-like 5
chr6_-_137146708 4.49 ENSMUST00000117919.8
RAS-like, estrogen-regulated, growth-inhibitor
chr1_-_134883645 3.86 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr1_-_134883577 3.80 ENSMUST00000168381.8
protein phosphatase 1, regulatory subunit 12B
chr16_-_45544960 3.75 ENSMUST00000096057.5
transgelin 3
chrX_-_142716200 3.61 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr18_+_23886765 3.56 ENSMUST00000115830.8
microtubule-associated protein, RP/EB family, member 2
chr2_+_69727599 3.53 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr8_+_94879235 3.53 ENSMUST00000034211.10
ENSMUST00000211930.2
ENSMUST00000211915.2
metallothionein 3
chr7_+_54485336 3.42 ENSMUST00000082373.8
leucine zipper protein 2
chr18_+_37651393 3.06 ENSMUST00000097609.3
protocadherin beta 22
chr11_+_59197746 2.85 ENSMUST00000000128.10
ENSMUST00000108783.4
wingless-type MMTV integration site family, member 9A
chr3_+_138019040 2.60 ENSMUST00000013455.13
ENSMUST00000106247.2
alcohol dehydrogenase 6A (class V)
chr13_+_43019718 2.54 ENSMUST00000131942.2
phosphatase and actin regulator 1
chr3_+_55689921 2.51 ENSMUST00000075422.6
mab-21-like 1
chr10_-_85847697 2.48 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr5_-_99091681 2.48 ENSMUST00000162619.8
ENSMUST00000162147.6
protein kinase, cGMP-dependent, type II
chr18_+_37827413 2.47 ENSMUST00000193414.2
protocadherin gamma subfamily A, 5
chr2_+_69727563 2.46 ENSMUST00000055758.16
ENSMUST00000112251.9
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_83554741 2.43 ENSMUST00000028499.11
integrin alpha V
chr3_+_55369149 2.34 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr18_+_86729184 2.33 ENSMUST00000068423.10
cerebellin 2 precursor protein
chr8_+_46338498 2.28 ENSMUST00000034053.7
PDZ and LIM domain 3
chrM_+_9870 2.27 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr14_-_109151590 2.26 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr2_+_124978518 2.25 ENSMUST00000238754.2
cortexin 2
chr19_-_50667079 2.25 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chr10_+_116013122 2.23 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr13_+_42834989 2.21 ENSMUST00000149235.8
phosphatase and actin regulator 1
chr18_-_10706701 2.21 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr8_+_46338557 2.02 ENSMUST00000210422.2
PDZ and LIM domain 3
chr5_-_86616849 2.02 ENSMUST00000101073.3
transmembrane protease, serine 11a
chr11_-_73217633 1.98 ENSMUST00000134079.2
aspartoacylase
chr9_-_79885063 1.94 ENSMUST00000093811.11
filamin A interacting protein 1
chrX_+_16485937 1.93 ENSMUST00000026013.6
monoamine oxidase A
chr2_+_124978612 1.92 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr16_-_56688024 1.89 ENSMUST00000232373.2
transmembrane protein 45a
chr9_-_79884920 1.86 ENSMUST00000239133.2
filamin A interacting protein 1
chr4_-_114991478 1.85 ENSMUST00000106545.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr10_+_127226180 1.82 ENSMUST00000077046.12
ENSMUST00000105250.9
R3H domain containing 2
chr13_-_53627110 1.79 ENSMUST00000021922.10
msh homeobox 2
chr3_-_50398027 1.74 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr4_+_108576846 1.74 ENSMUST00000178992.2
RIKEN cDNA 3110021N24 gene
chr5_+_29400981 1.73 ENSMUST00000160888.8
ENSMUST00000159272.8
ENSMUST00000001247.12
ENSMUST00000161398.8
ENSMUST00000160246.8
ring finger protein 32
chr2_+_32496990 1.72 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr9_+_113641615 1.69 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr9_-_119897328 1.67 ENSMUST00000177637.2
chemokine (C-X3-C motif) receptor 1
chrX_+_113384297 1.65 ENSMUST00000133447.2
kelch-like 4
chr2_+_110551927 1.63 ENSMUST00000111017.9
mucin 15
chr10_-_20600442 1.61 ENSMUST00000170265.8
phosphodiesterase 7B
chr2_+_32496957 1.56 ENSMUST00000113290.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr4_-_114991174 1.55 ENSMUST00000051400.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr2_+_110551685 1.45 ENSMUST00000111016.9
mucin 15
chrX_-_98514278 1.44 ENSMUST00000113797.4
ENSMUST00000113790.8
ENSMUST00000036354.7
ENSMUST00000167246.2
praja ring finger ubiquitin ligase 1
chr10_+_115854118 1.43 ENSMUST00000063470.11
protein tyrosine phosphatase, receptor type, R
chr9_+_109881083 1.39 ENSMUST00000164930.8
ENSMUST00000199498.5
microtubule-associated protein 4
chr16_+_13176238 1.37 ENSMUST00000149359.2
myocardin related transcription factor B
chr11_-_73217298 1.36 ENSMUST00000155630.9
aspartoacylase
chr9_-_119897358 1.35 ENSMUST00000064165.5
chemokine (C-X3-C motif) receptor 1
chr15_+_21111428 1.34 ENSMUST00000075132.8
cadherin 12
chrX_-_100129626 1.34 ENSMUST00000113710.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr19_+_5524701 1.33 ENSMUST00000165485.8
ENSMUST00000166253.8
ENSMUST00000167371.8
ENSMUST00000167855.8
ENSMUST00000070118.14
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr13_-_54713180 1.23 ENSMUST00000026989.15
RIKEN cDNA 4833439L19 gene
chr2_+_83554770 1.20 ENSMUST00000141725.3
integrin alpha V
chr12_-_40298072 1.15 ENSMUST00000169926.8
interferon-related developmental regulator 1
chr10_+_97318223 1.14 ENSMUST00000163448.4
decorin
chr5_+_104350475 1.08 ENSMUST00000066708.7
dentin matrix protein 1
chr16_-_88303859 1.02 ENSMUST00000069549.3
claudin 17
chr2_+_110427643 1.00 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chrX_+_151909893 0.98 ENSMUST00000163801.2
forkhead box R2
chr19_-_32173824 0.90 ENSMUST00000151822.2
sphingomyelin synthase 1
chr14_-_36641270 0.87 ENSMUST00000182797.8
coiled-coil serine rich 2
chr6_-_93769426 0.86 ENSMUST00000204788.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chrM_+_14138 0.83 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr16_-_19241884 0.78 ENSMUST00000206110.4
olfactory receptor 165
chr7_-_25112256 0.77 ENSMUST00000200880.4
ENSMUST00000074040.4
chemokine (C-X-C motif) ligand 17
chr19_-_38807600 0.76 ENSMUST00000025963.8
NOC3 like DNA replication regulator
chr4_-_14621805 0.74 ENSMUST00000042221.14
solute carrier family 26, member 7
chr18_+_31742565 0.69 ENSMUST00000164667.2
RIKEN cDNA B930094E09 gene
chr9_+_38119661 0.69 ENSMUST00000211975.3
olfactory receptor 893
chr7_-_103113358 0.69 ENSMUST00000214347.2
olfactory receptor 607
chr2_+_22959452 0.68 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr17_+_24072493 0.68 ENSMUST00000061725.8
protease, serine 32
chr3_-_72875187 0.65 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr9_+_20148415 0.64 ENSMUST00000086474.6
olfactory receptor 872
chrX_+_164953444 0.63 ENSMUST00000130880.9
ENSMUST00000056410.11
ENSMUST00000096252.10
ENSMUST00000087169.11
gem nuclear organelle associated protein 8
chr8_+_23901506 0.62 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr19_+_41921903 0.61 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr8_-_49008305 0.59 ENSMUST00000110346.9
ENSMUST00000211976.2
teneurin transmembrane protein 3
chrM_+_9459 0.59 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr2_+_110551976 0.58 ENSMUST00000090332.5
mucin 15
chr14_-_14255736 0.56 ENSMUST00000170111.3
potassium channel tetramerisation domain containing 6
chrX_+_158086253 0.55 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr3_+_5283577 0.54 ENSMUST00000175866.8
zinc finger homeodomain 4
chr15_+_25774070 0.51 ENSMUST00000125667.3
myosin X
chr19_+_53933271 0.51 ENSMUST00000025932.9
Shoc2, leucine rich repeat scaffold protein
chr3_+_5283606 0.50 ENSMUST00000026284.13
zinc finger homeodomain 4
chr7_-_107696793 0.49 ENSMUST00000217304.2
olfactory receptor 482
chr19_-_53933052 0.48 ENSMUST00000135402.4
BBSome interacting protein 1
chr11_+_102175985 0.44 ENSMUST00000156326.2
transmembrane and ubiquitin-like domain containing 2
chrM_-_14061 0.44 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr5_-_87716882 0.42 ENSMUST00000113314.3
sulfotransferase family 1D, member 1
chr10_-_43934774 0.42 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr1_-_4563821 0.42 ENSMUST00000191939.2
SRY (sex determining region Y)-box 17
chr13_-_103042554 0.42 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr14_+_80237691 0.40 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr9_+_38883609 0.40 ENSMUST00000216238.3
olfactory receptor 933
chr12_+_87840841 0.39 ENSMUST00000110147.3
eukaryotic translation initiation factor 1A domain containing 3
chr11_+_73051228 0.38 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_-_66672158 0.38 ENSMUST00000161879.8
ENSMUST00000159357.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_-_59127571 0.38 ENSMUST00000199675.2
ENSMUST00000170388.6
purinergic receptor P2Y, G-protein coupled 12
chr15_-_75777210 0.36 ENSMUST00000127550.2
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr6_+_132572871 0.36 ENSMUST00000076061.4
ENSMUST00000178961.2
proline rich protein 2
chr11_+_96177449 0.36 ENSMUST00000049352.8
homeobox B7
chr10_-_75946790 0.35 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr7_-_5325456 0.33 ENSMUST00000207520.2
NLR family, pyrin domain containing 2
chrX_+_96116202 0.32 ENSMUST00000033556.4
G protein-coupled receptor 15-like
chr4_-_154721288 0.31 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr2_+_83554868 0.30 ENSMUST00000111740.9
integrin alpha V
chr2_-_88559941 0.29 ENSMUST00000099815.2
olfactory receptor 1197
chr11_+_73489420 0.25 ENSMUST00000214228.2
olfactory receptor 384
chr2_+_87854404 0.25 ENSMUST00000217006.2
olfactory receptor 1161
chr10_+_102376109 0.23 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr18_+_32200781 0.22 ENSMUST00000025243.5
ENSMUST00000212675.2
IWS1, SUPT6 interacting protein
chr9_+_21634779 0.20 ENSMUST00000034713.9
low density lipoprotein receptor
chr13_+_22534534 0.18 ENSMUST00000226909.2
ENSMUST00000227167.2
ENSMUST00000226786.2
vomeronasal 1 receptor 198
chr19_+_13339600 0.17 ENSMUST00000215096.2
olfactory receptor 1467
chr11_+_29323618 0.17 ENSMUST00000040182.13
ENSMUST00000109477.2
coiled coil domain containing 88A
chr2_+_22959223 0.17 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr16_+_58967409 0.16 ENSMUST00000216957.3
olfactory receptor 195
chr5_+_67125759 0.16 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr10_+_75983285 0.15 ENSMUST00000020450.4
solute carrier family 5, member 4a
chr17_+_79919267 0.14 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr2_-_85481048 0.13 ENSMUST00000215548.3
olfactory receptor 1002
chr13_-_23041731 0.13 ENSMUST00000228645.2
vomeronasal 1 receptor 211
chr15_-_100321973 0.12 ENSMUST00000154676.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_-_86455575 0.11 ENSMUST00000077524.4
mab-21-like 2
chr2_-_88994435 0.11 ENSMUST00000099793.3
olfactory receptor 1224, pseudogene 1
chr18_+_4920513 0.11 ENSMUST00000126977.8
supervillin
chr6_+_30541581 0.09 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr2_-_86109346 0.08 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chrX_-_142716085 0.08 ENSMUST00000087313.10
doublecortin
chr7_-_102638531 0.06 ENSMUST00000215606.2
olfactory receptor 578
chr6_-_122317484 0.05 ENSMUST00000112600.9
polyhomeotic 1
chr3_+_103739877 0.05 ENSMUST00000062945.12
BCLl2-like 15
chr19_-_41921676 0.03 ENSMUST00000075280.12
ENSMUST00000112123.4
exosome component 1
chr2_-_87570322 0.03 ENSMUST00000214573.2
olfactory receptor 1138
chr8_-_19041062 0.02 ENSMUST00000066282.4
defensin beta 37
chr16_+_35803794 0.01 ENSMUST00000173555.8
karyopherin (importin) alpha 1
chr1_+_87983189 0.01 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr16_-_93726399 0.00 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 20.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.5 6.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.3 3.9 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
1.2 3.5 GO:0097212 lysosomal membrane organization(GO:0097212)
1.0 3.0 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.7 11.7 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.6 2.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.6 3.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.6 1.8 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.5 3.3 GO:0006083 acetate metabolic process(GO:0006083)
0.3 1.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 3.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 1.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 0.6 GO:2000041 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 3.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.4 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807) regulation of cardiac cell fate specification(GO:2000043)
0.1 0.8 GO:0033762 response to glucagon(GO:0033762)
0.1 5.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.2 GO:1903978 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of microglial cell activation(GO:1903978) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 2.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 6.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.5 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 2.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 4.8 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 4.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 3.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0010793 regulation of histone H3-K36 methylation(GO:0000414) regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 4.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.1 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 4.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.6 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0050718 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0034683 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.8 11.7 GO:0005883 neurofilament(GO:0005883)
0.6 1.7 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.1 7.7 GO:0031672 A band(GO:0031672)
0.1 3.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 19.2 GO:0043197 dendritic spine(GO:0043197)
0.1 3.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 1.1 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.0 GO:0016235 aggresome(GO:0016235)
0.0 8.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 4.3 GO:0030018 Z disc(GO:0030018)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 4.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0070469 respiratory chain(GO:0070469)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 3.7 GO:0043209 myelin sheath(GO:0043209)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 7.0 GO:0045202 synapse(GO:0045202)
0.0 0.1 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 20.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.1 3.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.8 6.9 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.4 2.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 2.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 3.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 1.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 1.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 6.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 5.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.5 GO:0005109 frizzled binding(GO:0005109)
0.1 5.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 10.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 9.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 3.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 5.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.9 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 23.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 3.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 4.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)