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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxb1

Z-value: 0.84

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Transcription factors associated with Hoxb1

Gene Symbol Gene ID Gene Info
Hoxb1
ENSMUSG00000018973.3 Hoxb1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb1mm39_v1_chr11_+_96256565_962565780.253.3e-02Click!

Activity profile of Hoxb1 motif

Sorted Z-values of Hoxb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_-_95426419 9.65 ENSMUST00000229933.2
ENSMUST00000166170.9
Nell2
NEL-like 2
chr6_-_58884038 9.11 ENSMUST00000059539.5
Nap1l5
nucleosome assembly protein 1-like 5
chr11_-_97913420 7.84 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr3_-_88669551 7.67 ENSMUST00000183267.2
Syt11
synaptotagmin XI
chrX_+_165127688 7.49 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
Gpm6b
glycoprotein m6b
chr15_+_74388044 6.10 ENSMUST00000042035.16
Adgrb1
adhesion G protein-coupled receptor B1
chr1_-_135934080 6.05 ENSMUST00000166193.9
Igfn1
immunoglobulin-like and fibronectin type III domain containing 1
chr10_-_33500583 5.85 ENSMUST00000161692.2
ENSMUST00000160299.2
ENSMUST00000019920.13
Clvs2
clavesin 2
chr2_+_65676111 5.85 ENSMUST00000122912.8
Csrnp3
cysteine-serine-rich nuclear protein 3
chr15_+_38740784 5.55 ENSMUST00000226440.3
ENSMUST00000239553.1
Baalc
brain and acute leukemia, cytoplasmic
chr6_-_124441731 5.31 ENSMUST00000008297.5
Clstn3
calsyntenin 3
chr2_+_65676176 5.12 ENSMUST00000053910.10
Csrnp3
cysteine-serine-rich nuclear protein 3
chr14_-_24053994 4.66 ENSMUST00000225431.2
ENSMUST00000188210.8
ENSMUST00000224787.2
ENSMUST00000225315.2
ENSMUST00000225556.2
ENSMUST00000223727.2
ENSMUST00000223655.2
ENSMUST00000224077.2
ENSMUST00000224812.2
ENSMUST00000224285.2
ENSMUST00000225471.2
ENSMUST00000224232.2
ENSMUST00000223749.2
ENSMUST00000224025.2
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr14_+_70314652 4.62 ENSMUST00000035908.3
Egr3
early growth response 3
chr17_+_27160356 4.53 ENSMUST00000229490.2
ENSMUST00000201702.5
ENSMUST00000177932.7
ENSMUST00000201349.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr1_+_153541020 4.37 ENSMUST00000152114.8
ENSMUST00000111812.8
Rgs8
regulator of G-protein signaling 8
chr14_+_70314727 4.36 ENSMUST00000225200.2
Egr3
early growth response 3
chrX_+_142301666 4.29 ENSMUST00000134402.8
Pak3
p21 (RAC1) activated kinase 3
chr4_-_91288221 4.21 ENSMUST00000102799.10
Elavl2
ELAV like RNA binding protein 1
chr6_-_28126124 4.17 ENSMUST00000115324.9
ENSMUST00000090512.10
Grm8
glutamate receptor, metabotropic 8
chr19_-_41732104 4.16 ENSMUST00000025993.10
Slit1
slit guidance ligand 1
chr2_+_156317416 4.00 ENSMUST00000029155.16
Epb41l1
erythrocyte membrane protein band 4.1 like 1
chr7_+_73040908 3.80 ENSMUST00000128471.2
ENSMUST00000139780.3
Rgma
repulsive guidance molecule family member A
chr1_-_25868788 3.77 ENSMUST00000151309.8
Adgrb3
adhesion G protein-coupled receptor B3
chr17_+_27160203 3.73 ENSMUST00000194598.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr18_+_66006119 3.50 ENSMUST00000025395.10
Grp
gastrin releasing peptide
chr1_-_25868592 3.28 ENSMUST00000135518.8
Adgrb3
adhesion G protein-coupled receptor B3
chr5_+_20112500 3.23 ENSMUST00000101558.10
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_76563281 3.18 ENSMUST00000056184.2
Bhlha9
basic helix-loop-helix family, member a9
chr19_-_5553804 3.16 ENSMUST00000189704.2
Nscme3l
NSE3 homolog, SMC5-SMC6 complex component like
chr1_+_127234441 3.16 ENSMUST00000171405.2
Mgat5
mannoside acetylglucosaminyltransferase 5
chr5_+_20112704 2.98 ENSMUST00000115267.7
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_142359099 2.87 ENSMUST00000126521.9
ENSMUST00000211094.2
Spx
spexin hormone
chrX_+_109857866 2.68 ENSMUST00000078229.5
Pou3f4
POU domain, class 3, transcription factor 4
chr12_+_38830081 2.47 ENSMUST00000095767.11
Etv1
ets variant 1
chr11_+_85243970 2.17 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
Bcas3
breast carcinoma amplified sequence 3
chr12_+_38830283 2.13 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
Etv1
ets variant 1
chr16_+_25620652 2.12 ENSMUST00000115304.8
ENSMUST00000115305.2
ENSMUST00000040231.13
ENSMUST00000115306.8
Trp63
transformation related protein 63
chr14_+_3576275 2.04 ENSMUST00000151926.8
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr5_-_138270995 2.04 ENSMUST00000161665.2
ENSMUST00000100530.8
ENSMUST00000161279.8
ENSMUST00000161647.8
Gal3st4
galactose-3-O-sulfotransferase 4
chr9_-_91247809 1.91 ENSMUST00000034927.13
Zic1
zinc finger protein of the cerebellum 1
chr10_-_88440869 1.91 ENSMUST00000119185.8
ENSMUST00000238199.2
Mybpc1
myosin binding protein C, slow-type
chr11_+_103024128 1.79 ENSMUST00000107037.8
ENSMUST00000124928.2
ENSMUST00000062530.5
Hexim2
hexamethylene bis-acetamide inducible 2
chr9_-_91247831 1.78 ENSMUST00000065360.5
Zic1
zinc finger protein of the cerebellum 1
chr1_-_135615831 1.62 ENSMUST00000190298.8
Nav1
neuron navigator 1
chr12_-_15866763 1.55 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
Trib2
tribbles pseudokinase 2
chr9_+_114917902 1.49 ENSMUST00000182363.8
Osbpl10
oxysterol binding protein-like 10
chr4_-_102971434 1.48 ENSMUST00000036557.15
ENSMUST00000036451.15
Dnai4
dynein axonemal intermediate chain 4
chr4_+_43669266 1.42 ENSMUST00000107864.8
Tmem8b
transmembrane protein 8B
chr2_+_119803230 1.40 ENSMUST00000229024.2
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr10_-_88440996 1.14 ENSMUST00000121629.8
Mybpc1
myosin binding protein C, slow-type
chr14_-_24054273 1.08 ENSMUST00000188285.7
ENSMUST00000190044.7
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_-_102187445 1.07 ENSMUST00000107132.3
ENSMUST00000073234.9
Atxn7l3
ataxin 7-like 3
chr5_-_82271183 1.04 ENSMUST00000186079.2
ENSMUST00000185607.2
1700031L13Rik
RIKEN cDNA 1700031L13 gene
chr9_+_50664207 1.03 ENSMUST00000034562.9
Cryab
crystallin, alpha B
chr2_-_90900525 0.96 ENSMUST00000153367.2
ENSMUST00000079976.10
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr9_+_50664288 0.90 ENSMUST00000214962.2
ENSMUST00000216755.2
Cryab
crystallin, alpha B
chr4_-_35845204 0.84 ENSMUST00000164772.8
ENSMUST00000065173.9
Lingo2
leucine rich repeat and Ig domain containing 2
chr1_+_178626003 0.82 ENSMUST00000160789.2
Kif26b
kinesin family member 26B
chr18_+_42644552 0.75 ENSMUST00000237602.2
ENSMUST00000236088.2
ENSMUST00000025375.15
Tcerg1
transcription elongation regulator 1 (CA150)
chr6_-_87510200 0.74 ENSMUST00000113637.9
ENSMUST00000071024.7
Arhgap25
Rho GTPase activating protein 25
chr4_-_102971752 0.66 ENSMUST00000106868.4
Dnai4
dynein axonemal intermediate chain 4
chr12_+_79255702 0.65 ENSMUST00000122227.8
Rdh12
retinol dehydrogenase 12
chr2_+_119803180 0.64 ENSMUST00000066058.8
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr12_+_79255678 0.60 ENSMUST00000021548.12
Rdh12
retinol dehydrogenase 12
chr1_-_9770434 0.59 ENSMUST00000088658.11
Mybl1
myeloblastosis oncogene-like 1
chr17_+_34866090 0.58 ENSMUST00000015605.15
Atf6b
activating transcription factor 6 beta
chr8_-_49296915 0.56 ENSMUST00000211812.2
Tenm3
teneurin transmembrane protein 3
chr8_-_88686188 0.55 ENSMUST00000109655.9
Zfp423
zinc finger protein 423
chr10_-_67120959 0.52 ENSMUST00000159002.2
ENSMUST00000077839.13
Nrbf2
nuclear receptor binding factor 2
chr10_+_4216353 0.49 ENSMUST00000045730.7
Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr17_-_89508103 0.47 ENSMUST00000035701.6
Fshr
follicle stimulating hormone receptor
chr18_-_56695333 0.46 ENSMUST00000066208.13
ENSMUST00000172734.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr2_-_90900628 0.46 ENSMUST00000111436.3
ENSMUST00000073575.12
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr9_+_108660989 0.42 ENSMUST00000192307.6
ENSMUST00000193560.6
ENSMUST00000194875.6
Ip6k2
inositol hexaphosphate kinase 2
chr4_+_58285957 0.42 ENSMUST00000081919.12
ENSMUST00000177951.8
ENSMUST00000098059.10
ENSMUST00000179951.2
ENSMUST00000102893.10
ENSMUST00000084578.12
ENSMUST00000098057.10
Musk
muscle, skeletal, receptor tyrosine kinase
chrX_-_7999009 0.37 ENSMUST00000130832.8
ENSMUST00000033506.13
ENSMUST00000115623.8
ENSMUST00000153839.2
Wdr13
WD repeat domain 13
chr17_+_87224776 0.35 ENSMUST00000042172.7
Tmem247
transmembrane protein 247
chr3_+_58433236 0.29 ENSMUST00000029387.15
Eif2a
eukaryotic translation initiation factor 2A
chr14_-_24054186 0.24 ENSMUST00000188991.7
ENSMUST00000224468.2
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_100633860 0.23 ENSMUST00000030257.15
ENSMUST00000097955.3
Cachd1
cache domain containing 1
chr17_+_34866160 0.19 ENSMUST00000173984.2
Atf6b
activating transcription factor 6 beta
chr8_-_117809188 0.15 ENSMUST00000109093.9
ENSMUST00000098375.6
Pkd1l2
polycystic kidney disease 1 like 2
chr9_-_107960528 0.14 ENSMUST00000159372.3
ENSMUST00000160249.8
Rnf123
ring finger protein 123
chr5_+_20112771 0.13 ENSMUST00000200443.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_97066937 0.11 ENSMUST00000043077.8
Thrsp
thyroid hormone responsive
chr18_-_42132106 0.06 ENSMUST00000097591.5
Grxcr2
glutaredoxin, cysteine rich 2
chr19_-_12879225 0.03 ENSMUST00000071484.4
Olfr1447
olfactory receptor 1447
chr2_-_153371861 0.01 ENSMUST00000035346.14
Nol4l
nucleolar protein 4-like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
1.4 7.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.9 7.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.8 4.5 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.7 2.1 GO:0060197 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) cloacal septation(GO:0060197)
0.7 3.5 GO:0036343 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.7 4.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.6 9.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.6 9.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.5 6.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.5 1.5 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 4.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 5.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.4 2.9 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.3 2.0 GO:0007256 activation of JNKK activity(GO:0007256) negative regulation of defense response to bacterium(GO:1900425)
0.3 4.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 2.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 4.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 3.8 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of receptor binding(GO:1900121)
0.2 1.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 3.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.5 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 2.7 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 8.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 7.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 9.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 4.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 11.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 4.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 5.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 6.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 3.7 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 3.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 4.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 7.0 GO:0043083 synaptic cleft(GO:0043083)
0.4 8.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 6.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.9 GO:0031045 dense core granule(GO:0031045)
0.1 7.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.1 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 4.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.0 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.1 GO:0000124 SAGA complex(GO:0000124)
0.1 9.4 GO:0043204 perikaryon(GO:0043204)
0.0 4.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 6.1 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0043194 axon initial segment(GO:0043194)
0.0 15.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 6.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 7.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 3.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.7 2.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.7 4.2 GO:0048495 Roundabout binding(GO:0048495)
0.6 4.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.6 4.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 2.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 7.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.0 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 3.8 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 6.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 4.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 5.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 3.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 7.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 9.6 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 2.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 4.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 15.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 4.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 14.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 4.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 9.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 4.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.8 PID BMP PATHWAY BMP receptor signaling
0.0 4.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 5.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 6.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 8.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 3.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 4.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events