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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxb2_Dlx2

Z-value: 0.79

Motif logo

Transcription factors associated with Hoxb2_Dlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000075588.7 Hoxb2
ENSMUSG00000023391.9 Dlx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb2mm39_v1_chr11_+_96242422_962424610.431.8e-04Click!
Dlx2mm39_v1_chr2_-_71377088_71377103-0.335.2e-03Click!

Activity profile of Hoxb2_Dlx2 motif

Sorted Z-values of Hoxb2_Dlx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_62576140 9.37 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr16_+_22737128 7.98 ENSMUST00000170805.9
fetuin beta
chr16_+_22737050 7.81 ENSMUST00000231768.2
fetuin beta
chr16_+_22737227 7.58 ENSMUST00000231880.2
fetuin beta
chr19_+_34078333 7.09 ENSMUST00000025685.8
lipase, family member M
chr9_+_43222104 6.95 ENSMUST00000034511.7
tripartite motif-containing 29
chr1_-_140111138 5.18 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr1_-_140111018 5.11 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr3_+_93301003 4.87 ENSMUST00000045912.3
repetin
chr15_-_101602734 4.84 ENSMUST00000023788.8
keratin 6A
chr5_-_134776101 4.54 ENSMUST00000015138.13
elastin
chr17_+_35844091 4.19 ENSMUST00000025273.9
psoriasis susceptibility 1 candidate 2 (human)
chr7_+_43430459 4.17 ENSMUST00000014058.11
kallikrein related-peptidase 10
chr16_+_42727926 3.79 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chrM_+_10167 3.63 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr15_-_101801351 3.62 ENSMUST00000100179.2
keratin 76
chr10_+_53213763 3.45 ENSMUST00000219491.2
ENSMUST00000163319.9
ENSMUST00000220197.2
ENSMUST00000046221.8
ENSMUST00000218468.2
ENSMUST00000219921.2
phospholamban
chr5_-_86521273 3.41 ENSMUST00000031175.12
transmembrane protease, serine 11d
chr16_+_44914397 3.29 ENSMUST00000061050.6
coiled-coil domain containing 80
chr16_-_56688024 3.28 ENSMUST00000232373.2
transmembrane protein 45a
chr18_-_43610829 3.14 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr4_-_14621805 3.01 ENSMUST00000042221.14
solute carrier family 26, member 7
chr18_-_43925932 2.92 ENSMUST00000237926.2
ENSMUST00000096570.4
predicted gene 94
chr18_+_44237474 2.90 ENSMUST00000081271.7
serine peptidase inhibitor, Kazal type 12
chr10_-_85847697 2.88 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr13_-_53627110 2.80 ENSMUST00000021922.10
msh homeobox 2
chr4_-_14621497 2.73 ENSMUST00000149633.2
solute carrier family 26, member 7
chr10_+_127734384 2.71 ENSMUST00000047134.8
4short chain dehydrogenase/reductase family 9C, member 7
chr7_-_28246530 2.69 ENSMUST00000239002.2
ENSMUST00000057974.4
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr1_+_172383499 2.65 ENSMUST00000061835.10
V-set and immunoglobulin domain containing 8
chr3_+_59989282 2.64 ENSMUST00000029326.6
succinate receptor 1
chr10_-_107321938 2.62 ENSMUST00000000445.2
myogenic factor 5
chr4_-_14621669 2.51 ENSMUST00000143105.2
solute carrier family 26, member 7
chrM_+_9870 2.49 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr19_-_42117420 2.45 ENSMUST00000161873.2
ENSMUST00000018965.4
arginine vasopressin-induced 1
chr9_-_71070506 2.39 ENSMUST00000074465.9
aquaporin 9
chr14_+_33662976 2.34 ENSMUST00000100720.2
growth differentiation factor 2
chr12_-_25147139 2.33 ENSMUST00000221761.2
inhibitor of DNA binding 2
chr15_+_31224616 2.32 ENSMUST00000186547.7
death-associated protein
chr18_+_4920513 2.29 ENSMUST00000126977.8
supervillin
chr11_-_121410152 2.19 ENSMUST00000092298.6
zinc finger protein 750
chr15_+_55171138 2.13 ENSMUST00000023053.12
ENSMUST00000110217.10
collagen, type XIV, alpha 1
chr11_+_115225557 2.10 ENSMUST00000106543.8
ENSMUST00000019006.5
otopetrin 3
chr13_+_75855695 2.05 ENSMUST00000222194.2
ENSMUST00000223535.2
ENSMUST00000222853.2
elongation factor for RNA polymerase II 2
chr5_-_86893645 2.02 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr14_-_56181993 1.99 ENSMUST00000022834.7
ENSMUST00000226280.2
chymase 1, mast cell
chr8_-_62355690 1.97 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr2_+_83554741 1.96 ENSMUST00000028499.11
integrin alpha V
chr19_-_7943365 1.95 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr1_+_107350411 1.86 ENSMUST00000086690.6
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr15_-_101482320 1.80 ENSMUST00000042957.6
keratin 75
chr18_+_44237577 1.80 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr1_-_106980033 1.80 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr6_+_15196950 1.78 ENSMUST00000140557.8
ENSMUST00000131414.8
ENSMUST00000115469.8
forkhead box P2
chrX_+_132751729 1.74 ENSMUST00000033602.9
tenomodulin
chr3_-_49711765 1.72 ENSMUST00000035931.13
protocadherin 18
chr11_+_67689094 1.71 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chrM_+_11735 1.67 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr2_+_83554770 1.63 ENSMUST00000141725.3
integrin alpha V
chr3_-_92031247 1.62 ENSMUST00000070284.4
proline rich 9
chr2_+_27055245 1.61 ENSMUST00000000910.7
dopamine beta hydroxylase
chr14_+_51333816 1.60 ENSMUST00000169895.3
ribonuclease, RNase A family 4
chr5_-_103777145 1.60 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr3_-_49711706 1.59 ENSMUST00000191794.2
protocadherin 18
chr18_+_84106796 1.57 ENSMUST00000235383.2
zinc binding alcohol dehydrogenase, domain containing 2
chr10_-_43934774 1.51 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr17_-_35100980 1.50 ENSMUST00000152417.8
ENSMUST00000146299.8
complement component 2 (within H-2S)
predicted gene 20547
chr2_+_103242027 1.49 ENSMUST00000239273.2
ENSMUST00000164172.8
E74-like factor 5
chr3_+_82915031 1.48 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr13_-_114595122 1.46 ENSMUST00000231252.2
follistatin
chr15_+_31224555 1.45 ENSMUST00000186109.2
death-associated protein
chr18_+_36414122 1.43 ENSMUST00000051301.6
purine rich element binding protein A
chr15_+_25774070 1.42 ENSMUST00000125667.3
myosin X
chr10_+_32959472 1.40 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr5_+_92535705 1.39 ENSMUST00000138687.2
ENSMUST00000124509.2
ADP-ribosyltransferase 3
chr2_-_111100733 1.39 ENSMUST00000099619.6
olfactory receptor 1277
chr16_+_44913974 1.38 ENSMUST00000099498.10
coiled-coil domain containing 80
chr10_-_44024843 1.38 ENSMUST00000200401.2
crystallin beta-gamma domain containing 1
chr6_-_115569504 1.37 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr6_-_101176147 1.36 ENSMUST00000239140.2
PDZ domain containing RING finger 3
chr5_+_90708962 1.35 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr10_+_68987257 1.35 ENSMUST00000167286.8
Rho-related BTB domain containing 1
chr11_-_99441687 1.34 ENSMUST00000092700.5
keratin associated protein 3-3
chr7_-_48497771 1.33 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr18_+_9707595 1.33 ENSMUST00000234965.2
collectin sub-family member 12
chr16_-_97564910 1.31 ENSMUST00000019386.10
receptor-interacting serine-threonine kinase 4
chr6_-_52181393 1.30 ENSMUST00000048794.7
homeobox A5
chr8_+_23901506 1.29 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr11_-_99412162 1.29 ENSMUST00000107445.8
keratin 39
chr2_+_110551927 1.29 ENSMUST00000111017.9
mucin 15
chr9_-_79885063 1.29 ENSMUST00000093811.11
filamin A interacting protein 1
chr17_-_35101069 1.28 ENSMUST00000025230.15
complement component 2 (within H-2S)
chr3_-_88194517 1.27 ENSMUST00000165196.8
predicted gene, 38392
chr1_-_189902868 1.26 ENSMUST00000177288.4
ENSMUST00000175916.8
prospero homeobox 1
chr5_+_90666791 1.25 ENSMUST00000113179.9
ENSMUST00000128740.2
afamin
chr15_-_96929086 1.24 ENSMUST00000230086.2
solute carrier family 38, member 4
chrX_+_156481906 1.24 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr4_-_104733580 1.24 ENSMUST00000064873.9
ENSMUST00000106808.10
ENSMUST00000048947.15
complement component 8, alpha polypeptide
chr19_+_24651362 1.24 ENSMUST00000057243.6
transmembrane protein 252
chr3_-_129518723 1.24 ENSMUST00000199615.5
ENSMUST00000197079.5
epidermal growth factor
chr2_+_74528071 1.24 ENSMUST00000059272.10
homeobox D9
chrX_+_156482116 1.23 ENSMUST00000112521.8
small muscle protein, X-linked
chr6_-_83654789 1.23 ENSMUST00000037882.8
CD207 antigen
chr2_+_110551976 1.23 ENSMUST00000090332.5
mucin 15
chr11_-_99412084 1.22 ENSMUST00000076948.2
keratin 39
chr9_-_79884920 1.22 ENSMUST00000239133.2
filamin A interacting protein 1
chr8_-_11329656 1.21 ENSMUST00000208095.2
collagen, type IV, alpha 1
chr16_+_37400590 1.19 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr3_+_63988968 1.19 ENSMUST00000029406.6
vomeronasal 2, receptor 1
chr17_-_43003135 1.19 ENSMUST00000170723.8
ENSMUST00000164524.2
ENSMUST00000024711.11
ENSMUST00000167993.8
adhesion G protein-coupled receptor F4
chr1_-_119576347 1.18 ENSMUST00000027632.14
ENSMUST00000187194.2
erythrocyte membrane protein band 4.1 like 5
chr16_+_37400500 1.18 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr6_-_147165623 1.18 ENSMUST00000052296.9
ENSMUST00000204197.2
parathyroid hormone-like peptide
chr12_-_57592907 1.18 ENSMUST00000044380.8
forkhead box A1
chr7_+_43418321 1.17 ENSMUST00000107970.8
kallikrein related-peptidase 12
chr6_+_37847721 1.17 ENSMUST00000031859.14
ENSMUST00000120428.8
tripartite motif-containing 24
chr2_+_83554868 1.16 ENSMUST00000111740.9
integrin alpha V
chr6_-_128252540 1.13 ENSMUST00000130454.8
TEA domain family member 4
chr1_-_45542442 1.12 ENSMUST00000086430.5
collagen, type V, alpha 2
chr2_+_110551685 1.12 ENSMUST00000111016.9
mucin 15
chr17_-_29226700 1.12 ENSMUST00000233441.2
serine/threonine kinase 38
chr2_+_132689640 1.11 ENSMUST00000124836.8
ENSMUST00000154160.2
cardiolipin synthase 1
chr14_+_26722319 1.10 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr17_-_71160477 1.10 ENSMUST00000118283.8
TGFB-induced factor homeobox 1
chr1_+_88128323 1.10 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr2_-_27365633 1.10 ENSMUST00000138693.8
ENSMUST00000113941.9
ENSMUST00000077737.13
bromodomain containing 3
chr16_+_33504740 1.10 ENSMUST00000232568.2
heart development protein with EGF-like domains 1
chr7_+_43418404 1.08 ENSMUST00000014063.6
kallikrein related-peptidase 12
chr13_+_55547498 1.08 ENSMUST00000057167.9
solute carrier family 34 (sodium phosphate), member 1
chr2_-_72817060 1.07 ENSMUST00000112062.2
predicted gene 11084
chr13_+_23991010 1.07 ENSMUST00000006786.11
ENSMUST00000099697.3
solute carrier family 17 (sodium phosphate), member 2
chr2_+_103255165 1.06 ENSMUST00000126290.2
E74-like factor 5
chr8_-_45747883 1.05 ENSMUST00000026907.6
kallikrein B, plasma 1
chr9_-_18297277 1.05 ENSMUST00000166825.8
N-acetylated alpha-linked acidic dipeptidase 2
chr15_-_60793115 1.05 ENSMUST00000096418.5
alpha-1-B glycoprotein
chr6_-_101354858 1.04 ENSMUST00000075994.11
PDZ domain containing RING finger 3
chr10_+_102376109 1.03 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr16_-_35891739 1.03 ENSMUST00000231351.2
ENSMUST00000004057.9
family with sequence similarity 162, member A
chr7_+_107679062 1.02 ENSMUST00000213601.2
olfactory receptor 481
chr2_+_9887427 1.00 ENSMUST00000114919.2
RIKEN cDNA 4930412O13 gene
chr7_-_12829100 0.99 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr19_-_39637489 0.99 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr6_-_30304512 0.99 ENSMUST00000094543.3
ENSMUST00000102993.10
ubiquitin-conjugating enzyme E2H
chr17_-_48145466 0.99 ENSMUST00000066368.13
MyoD family inhibitor
chr5_-_53864874 0.99 ENSMUST00000031093.5
cholecystokinin A receptor
chr14_-_118289557 0.99 ENSMUST00000022725.4
dopachrome tautomerase
chrX_+_99019176 0.98 ENSMUST00000113781.8
ENSMUST00000113783.8
ENSMUST00000113779.8
ENSMUST00000113776.8
ENSMUST00000113775.8
ENSMUST00000113780.8
ENSMUST00000113778.8
ENSMUST00000113777.8
ENSMUST00000071453.3
ectodysplasin-A
chr16_-_88303859 0.98 ENSMUST00000069549.3
claudin 17
chr5_-_53864595 0.98 ENSMUST00000200691.4
cholecystokinin A receptor
chr11_+_96209093 0.97 ENSMUST00000049241.9
homeobox B4
chr12_-_104439589 0.96 ENSMUST00000021513.6
goosecoid homeobox
chr10_-_125164399 0.95 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_+_107456731 0.94 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr17_+_71326510 0.94 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr13_-_114595475 0.93 ENSMUST00000022287.8
ENSMUST00000223640.3
follistatin
chr2_+_87137925 0.93 ENSMUST00000216396.3
olfactory receptor 1118
chr1_-_134883645 0.92 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr15_+_31225302 0.91 ENSMUST00000186425.7
death-associated protein
chr17_+_71326542 0.91 ENSMUST00000179759.3
myomesin 1
chr1_-_171854818 0.89 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr15_+_31224460 0.89 ENSMUST00000044524.16
death-associated protein
chr1_+_151446893 0.89 ENSMUST00000134499.8
niban apoptosis regulator 1
chr9_+_102595628 0.88 ENSMUST00000156485.2
ENSMUST00000145937.2
ENSMUST00000134483.2
ENSMUST00000190047.7
angiomotin-like 2
chr15_-_100322089 0.88 ENSMUST00000154331.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_87725306 0.86 ENSMUST00000217436.2
olfactory receptor 1153
chr15_+_37233280 0.86 ENSMUST00000161405.8
ENSMUST00000022895.15
ENSMUST00000161532.2
grainyhead like transcription factor 2
chr9_-_66421868 0.86 ENSMUST00000056890.10
F-box and leucine-rich repeat protein 22
chr2_+_31204314 0.86 ENSMUST00000113532.9
hemicentin 2
chr11_-_99265721 0.84 ENSMUST00000006963.3
keratin 28
chr2_-_86109346 0.83 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr3_-_24837772 0.82 ENSMUST00000203414.2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr17_-_29226886 0.82 ENSMUST00000232723.2
serine/threonine kinase 38
chr3_+_159545309 0.79 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chrM_+_7006 0.79 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr3_+_138058139 0.78 ENSMUST00000090166.5
alcohol dehydrogenase 6B (class V)
chr9_+_20148415 0.76 ENSMUST00000086474.6
olfactory receptor 872
chr15_-_100321973 0.76 ENSMUST00000154676.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_-_131662707 0.76 ENSMUST00000072404.3
taste receptor, type 2, member 104
chr1_-_134883577 0.75 ENSMUST00000168381.8
protein phosphatase 1, regulatory subunit 12B
chrX_-_99638466 0.75 ENSMUST00000053373.2
pyrimidinergic receptor P2Y, G-protein coupled, 4
chrX_+_82898974 0.74 ENSMUST00000239269.2
dystrophin, muscular dystrophy
chr7_-_103094646 0.73 ENSMUST00000215417.2
olfactory receptor 605
chr12_+_111780604 0.73 ENSMUST00000021714.9
ENSMUST00000223211.2
ENSMUST00000222843.2
ENSMUST00000221375.2
zinc finger, FYVE domain containing 21
chr6_-_84565613 0.73 ENSMUST00000204146.3
cytochrome P450, family 26, subfamily b, polypeptide 1
chr12_+_38830283 0.72 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
ets variant 1
chr12_-_101784727 0.70 ENSMUST00000222587.2
fibulin 5
chr4_+_8690398 0.70 ENSMUST00000127476.8
chromodomain helicase DNA binding protein 7
chr3_+_121838076 0.70 ENSMUST00000013995.13
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_19280850 0.70 ENSMUST00000102999.2
cyclic nucleotide gated channel beta 3
chr9_+_121780054 0.69 ENSMUST00000043011.9
ENSMUST00000214536.3
ENSMUST00000215990.3
golgi associated kinase 1A
chrX_+_138464065 0.69 ENSMUST00000113027.8
ring finger protein 128
chr8_-_26609153 0.69 ENSMUST00000037182.14
hook microtubule tethering protein 3
chr13_-_56399976 0.69 ENSMUST00000058475.6
neurogenin 1
chr16_+_34815177 0.68 ENSMUST00000231589.2
myosin, light polypeptide kinase
chr11_+_23256883 0.68 ENSMUST00000180046.8
ubiquitin specific peptidase 34
chr8_-_41494890 0.68 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr1_+_88093726 0.67 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr18_-_44795317 0.67 ENSMUST00000164666.6
mutated in colorectal cancers
chr13_-_103042294 0.67 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr16_+_43574389 0.67 ENSMUST00000229953.2
dopamine receptor D3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
1.1 10.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.9 2.8 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.9 8.2 GO:0019532 oxalate transport(GO:0019532)
0.8 2.3 GO:0001966 thigmotaxis(GO:0001966)
0.6 1.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.6 2.4 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.5 1.6 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.5 2.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.4 1.3 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.4 1.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.4 1.3 GO:2000041 response to heparin(GO:0071503) cellular response to heparin(GO:0071504) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 1.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.4 23.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 1.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.4 1.2 GO:0060618 nipple development(GO:0060618)
0.4 1.2 GO:0061144 alveolar secondary septum development(GO:0061144)
0.4 2.6 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.4 1.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.3 3.4 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.3 2.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.3 2.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 1.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 2.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.9 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 0.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.1 GO:0003017 lymph circulation(GO:0003017)
0.3 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 2.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 0.8 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.2 1.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 0.7 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.2 1.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.7 GO:0021553 olfactory nerve development(GO:0021553)
0.2 1.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.2 0.7 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.2 2.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 1.8 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 0.7 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 1.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.6 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.2 0.6 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.2 0.9 GO:0072199 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 1.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.7 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.2 3.6 GO:0048733 sebaceous gland development(GO:0048733)
0.2 4.8 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.2 3.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 0.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.6 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.4 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 1.9 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.1 0.7 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.7 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.4 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 1.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.4 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 1.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 5.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.3 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 1.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.0 GO:0014029 neural crest formation(GO:0014029)
0.1 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 5.7 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 4.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 2.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 1.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.1 GO:0048822 enucleate erythrocyte development(GO:0048822)
0.1 1.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.2 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.6 GO:0035878 nail development(GO:0035878)
0.1 0.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.2 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 0.2 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 5.4 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.3 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 1.0 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.5 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 1.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 2.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.6 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 4.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.6 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0090336 regulation of brown fat cell differentiation(GO:0090335) positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.6 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 4.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.7 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 1.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 2.3 GO:0019236 response to pheromone(GO:0019236)
0.0 5.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0006907 pinocytosis(GO:0006907)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.1 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 3.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.2 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.5 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 13.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
1.1 5.6 GO:0071953 elastic fiber(GO:0071953)
0.6 1.7 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.5 1.6 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.4 1.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 1.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.5 GO:0005927 muscle tendon junction(GO:0005927)
0.3 0.9 GO:0060187 cell pole(GO:0060187)
0.2 1.5 GO:0070826 paraferritin complex(GO:0070826)
0.2 6.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.6 GO:0005712 chiasma(GO:0005712) late recombination nodule(GO:0005715)
0.2 8.2 GO:0045095 keratin filament(GO:0045095)
0.2 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.2 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.8 GO:0035841 new growing cell tip(GO:0035841)
0.2 3.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 3.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 6.8 GO:0001533 cornified envelope(GO:0001533)
0.1 9.7 GO:0070469 respiratory chain(GO:0070469)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 1.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.5 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 7.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 1.7 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 1.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 6.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 32.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 3.3 GO:0030141 secretory granule(GO:0030141)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.3 GO:0001851 complement component C3b binding(GO:0001851)
1.1 23.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 1.6 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 3.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.5 4.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 2.4 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.5 8.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.4 1.2 GO:0008431 vitamin E binding(GO:0008431)
0.4 1.6 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.4 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 8.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 7.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 5.6 GO:0070513 death domain binding(GO:0070513)
0.2 0.7 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.2 1.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 0.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 1.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 0.6 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.2 1.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 4.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.7 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.2 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 2.4 GO:0048185 activin binding(GO:0048185)
0.1 0.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 4.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 9.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.7 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 3.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.5 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 1.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 8.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 11.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 2.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 7.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 8.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 11.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 7.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.5 PID FGF PATHWAY FGF signaling pathway
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 2.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.6 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 2.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 5.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis