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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxb3

Z-value: 1.13

Motif logo

Transcription factors associated with Hoxb3

Gene Symbol Gene ID Gene Info
ENSMUSG00000048763.12 Hoxb3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb3mm39_v1_chr11_+_96214078_96214152-0.009.8e-01Click!

Activity profile of Hoxb3 motif

Sorted Z-values of Hoxb3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_70383976 12.82 ENSMUST00000103393.2
immunoglobulin kappa variable 6-15
chr6_-_69704122 11.93 ENSMUST00000103364.3
immunoglobulin kappa variable 5-48
chr6_-_69282389 9.75 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr12_-_113790741 8.71 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr6_-_69415741 7.83 ENSMUST00000103354.3
immunoglobulin kappa variable 4-59
chr5_-_134975773 7.36 ENSMUST00000051401.4
claudin 4
chr2_-_32277773 6.68 ENSMUST00000050785.14
lipocalin 2
chr5_-_143963413 6.60 ENSMUST00000031622.13
oncomodulin
chr12_-_114672701 6.56 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr19_+_58748132 6.41 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr12_-_114117264 6.11 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr6_+_68518603 6.00 ENSMUST00000168090.3
ENSMUST00000103326.3
immunoglobulin kappa variable 1-99
chr6_-_69394425 5.77 ENSMUST00000199160.2
immunoglobulin kappa chain variable 4-61
chr14_+_99536111 5.23 ENSMUST00000005279.8
Kruppel-like factor 5
chr9_+_5298669 5.19 ENSMUST00000238505.2
caspase 1
chr8_-_58106057 4.96 ENSMUST00000034021.12
polypeptide N-acetylgalactosaminyltransferase 7
chrX_+_56257374 4.84 ENSMUST00000033466.2
CD40 ligand
chr3_-_14873406 4.82 ENSMUST00000181860.8
ENSMUST00000144327.3
carbonic anhydrase 1
chr6_-_68887922 4.74 ENSMUST00000103337.3
immunoglobulin kappa variable 4-86
chr8_-_110688716 4.71 ENSMUST00000001722.14
ENSMUST00000051430.7
MARVEL (membrane-associating) domain containing 3
chr6_-_69553484 4.68 ENSMUST00000103357.4
immunoglobulin kappa variable 4-57
chr2_-_32278245 4.63 ENSMUST00000192241.2
lipocalin 2
chr9_+_53678801 4.51 ENSMUST00000048670.10
solute carrier family 35, member F2
chr13_+_19528728 4.36 ENSMUST00000179181.3
T cell receptor gamma, constant 4
chr6_-_68994064 4.31 ENSMUST00000103341.4
immunoglobulin kappa variable 4-80
chr3_-_15902583 4.24 ENSMUST00000108354.8
ENSMUST00000108349.2
ENSMUST00000108352.9
ENSMUST00000108350.8
ENSMUST00000050623.11
signal-regulatory protein beta 1C
chr6_-_69245427 4.15 ENSMUST00000103348.3
immunoglobulin kappa chain variable 4-70
chr19_-_5610628 4.11 ENSMUST00000025861.3
ovo like zinc finger 1
chr8_-_58106027 4.08 ENSMUST00000110316.3
polypeptide N-acetylgalactosaminyltransferase 7
chr5_-_143963461 4.02 ENSMUST00000110702.2
oncomodulin
chr10_-_75946790 3.96 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr10_+_75983285 3.82 ENSMUST00000020450.4
solute carrier family 5, member 4a
chr5_+_122344854 3.74 ENSMUST00000145854.8
hydrogen voltage-gated channel 1
chr6_+_41928559 3.70 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr6_-_68887957 3.67 ENSMUST00000200454.2
immunoglobulin kappa variable 4-86
chr2_+_118877594 3.64 ENSMUST00000152380.8
ENSMUST00000099542.9
kinetochore scaffold 1
chr4_-_119151717 3.64 ENSMUST00000079644.13
Y box protein 1
chr4_+_3938881 3.58 ENSMUST00000108386.8
ENSMUST00000121110.8
ENSMUST00000149544.8
coiled-coil-helix-coiled-coil-helix domain containing 7
chr6_-_69678271 3.56 ENSMUST00000103363.2
immunoglobulin kappa variable 4-50
chr6_-_125357756 3.52 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr1_+_182392577 3.44 ENSMUST00000048941.14
calpain 8
chr10_+_115854118 3.39 ENSMUST00000063470.11
protein tyrosine phosphatase, receptor type, R
chr11_-_94673526 3.35 ENSMUST00000100554.8
transmembrane protein 92
chr6_-_69162381 3.27 ENSMUST00000103344.3
immunoglobulin kappa variable 4-74
chr2_+_118877610 3.13 ENSMUST00000153300.8
ENSMUST00000028799.12
kinetochore scaffold 1
chr10_-_128361731 3.07 ENSMUST00000026427.8
extended synaptotagmin-like protein 1
chr6_-_130106861 2.97 ENSMUST00000014476.6
killer cell lectin-like receptor, subfamily A, member 8
chr4_+_3938903 2.76 ENSMUST00000121210.8
ENSMUST00000121651.8
ENSMUST00000041122.11
ENSMUST00000120732.8
ENSMUST00000119307.8
ENSMUST00000123769.8
coiled-coil-helix-coiled-coil-helix domain containing 7
chr8_-_41494890 2.75 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr11_-_103247150 2.74 ENSMUST00000136491.3
ENSMUST00000107023.3
Rho GTPase activating protein 27
chr9_-_119170456 2.68 ENSMUST00000139870.2
myeloid differentiation primary response gene 88
chr6_-_129449739 2.67 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr13_-_74956640 2.65 ENSMUST00000231578.2
calpastatin
chr1_-_192880260 2.61 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr13_-_74956030 2.47 ENSMUST00000065629.6
calpastatin
chr6_-_68784692 2.46 ENSMUST00000103334.4
immunoglobulin kappa chain variable 4-90
chr5_+_63969706 2.46 ENSMUST00000081747.8
ENSMUST00000196575.5
RIKEN cDNA 0610040J01 gene
chr13_+_23966524 2.46 ENSMUST00000074067.4
tripartite motif-containing 38
chr3_-_15491482 2.41 ENSMUST00000099201.9
ENSMUST00000194144.3
ENSMUST00000192700.3
signal-regulatory protein beta 1A
chr11_+_43572825 2.38 ENSMUST00000061070.6
ENSMUST00000094294.5
PWWP domain containing 2A
chr19_-_32038838 2.37 ENSMUST00000096119.5
N-acylsphingosine amidohydrolase 2
chr16_+_35861554 2.33 ENSMUST00000042203.10
WD repeat domain 5B
chr3_-_15640045 2.32 ENSMUST00000192382.6
ENSMUST00000195778.3
ENSMUST00000091319.7
signal-regulatory protein beta 1B
chr15_+_10952418 2.32 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr1_+_157334347 2.31 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr4_-_3938352 2.30 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr1_+_157334298 2.24 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr10_+_128173603 2.23 ENSMUST00000005826.9
citrate synthase
chr2_+_36120438 2.21 ENSMUST00000062069.6
prostaglandin-endoperoxide synthase 1
chr17_+_88748139 2.19 ENSMUST00000112238.9
ENSMUST00000155640.2
forkhead box N2
chrX_+_106299484 2.16 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr10_+_26648473 2.15 ENSMUST00000039557.9
Rho GTPase activating protein 18
chr1_-_144427302 2.12 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr12_-_55061117 2.10 ENSMUST00000172875.8
bromodomain adjacent to zinc finger domain 1A
chr5_-_137784912 2.06 ENSMUST00000031740.16
methylphosphate capping enzyme
chr15_-_9529898 2.03 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr11_-_99482165 2.03 ENSMUST00000104930.2
keratin associated protein 1-3
chr1_+_40363701 2.00 ENSMUST00000095020.9
ENSMUST00000194296.6
interleukin 1 receptor-like 2
chr10_+_127502986 1.99 ENSMUST00000118728.8
nuclear envelope integral membrane protein 1
chr16_+_44632096 1.95 ENSMUST00000176819.8
ENSMUST00000176321.8
CD200 receptor 4
chr10_+_102210290 1.90 ENSMUST00000120748.2
MGAT4 family, member C
chr14_+_26722319 1.82 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr18_+_12466876 1.74 ENSMUST00000092070.13
laminin, alpha 3
chr2_+_71219561 1.73 ENSMUST00000028408.3
histone aminotransferase 1
chr16_+_22676589 1.73 ENSMUST00000004574.14
ENSMUST00000178320.2
ENSMUST00000166487.10
DnaJ heat shock protein family (Hsp40) member B11
chr4_-_140501507 1.58 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr10_+_32959472 1.57 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr6_-_69020489 1.53 ENSMUST00000103342.4
immunoglobulin kappa variable 4-79
chr5_-_137784943 1.47 ENSMUST00000132726.2
methylphosphate capping enzyme
chr2_+_69050315 1.46 ENSMUST00000005364.12
ENSMUST00000112317.3
glucose-6-phosphatase, catalytic, 2
chr17_-_7620095 1.44 ENSMUST00000115747.3
tubulin tyrosine ligase-like family, member 2
chr2_+_89808124 1.41 ENSMUST00000061830.2
olfactory receptor 1260
chr7_-_44778050 1.39 ENSMUST00000209711.2
ENSMUST00000211037.2
ENSMUST00000209927.2
ENSMUST00000209815.2
ENSMUST00000210918.2
ENSMUST00000150350.9
ribosomal protein L13A
chr1_+_54289833 1.37 ENSMUST00000027128.11
coiled-coil domain containing 150
chr1_-_171854818 1.36 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr5_-_137529465 1.35 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr19_-_40371016 1.33 ENSMUST00000225766.3
sorbin and SH3 domain containing 1
chr4_-_131802561 1.32 ENSMUST00000105970.8
ENSMUST00000105975.8
erythrocyte membrane protein band 4.1
chr6_-_112364974 1.25 ENSMUST00000238755.2
ENSMUST00000060847.6
ssu-2 homolog (C. elegans)
chr7_-_44741622 1.23 ENSMUST00000210469.2
ENSMUST00000211352.2
ENSMUST00000019683.11
reticulocalbin 3, EF-hand calcium binding domain
chr2_-_157179344 1.21 ENSMUST00000109536.8
growth hormone releasing hormone
chr11_+_95275458 1.21 ENSMUST00000021243.16
ENSMUST00000146556.2
solute carrier family 35, member B1
chr17_-_33904386 1.21 ENSMUST00000087582.13
heterogeneous nuclear ribonucleoprotein M
chr5_+_140593075 1.18 ENSMUST00000031555.3
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_131802606 1.17 ENSMUST00000146021.8
erythrocyte membrane protein band 4.1
chr19_-_56378309 1.17 ENSMUST00000166203.2
ENSMUST00000167239.8
nebulin-related anchoring protein
chr5_+_137015873 1.14 ENSMUST00000004968.11
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr9_-_50472620 1.12 ENSMUST00000217236.2
testis expressed 12
chr5_-_137015683 1.09 ENSMUST00000034953.14
ENSMUST00000085941.12
zinc finger, HIT domain containing 1
chr14_-_59602859 1.09 ENSMUST00000161031.2
PHD finger protein 11D
chr8_+_23901506 1.08 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr11_-_45845992 1.05 ENSMUST00000109254.2
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr11_+_49327451 1.05 ENSMUST00000215226.2
olfactory receptor 1388
chr9_-_50472605 1.01 ENSMUST00000034568.7
testis expressed 12
chr2_+_85648823 1.00 ENSMUST00000214416.2
olfactory receptor 1018
chr2_+_127696548 0.99 ENSMUST00000028859.8
acyl-Coenzyme A oxidase-like
chr7_-_44741609 0.95 ENSMUST00000210734.2
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_23650205 0.95 ENSMUST00000115354.2
ring finger protein 133
chr14_+_62529924 0.93 ENSMUST00000166879.8
ribonuclease H2, subunit B
chr14_-_59602882 0.93 ENSMUST00000160425.8
ENSMUST00000095157.11
PHD finger protein 11D
chr14_+_54701594 0.93 ENSMUST00000022782.10
low-density lipoprotein receptor-related protein 10
chr5_-_82272549 0.93 ENSMUST00000188072.2
ENSMUST00000185410.2
RIKEN cDNA 1700031L13 gene
chr13_-_23929490 0.93 ENSMUST00000091752.5
H3 clustered histone 3
chr10_+_115979787 0.91 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr6_+_65019793 0.91 ENSMUST00000204696.3
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_-_44741138 0.89 ENSMUST00000210527.2
reticulocalbin 3, EF-hand calcium binding domain
chrX_+_13147209 0.87 ENSMUST00000000804.7
DEAD box helicase 3, X-linked
chr6_-_115014777 0.86 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr17_-_33904345 0.85 ENSMUST00000234474.2
ENSMUST00000139302.8
ENSMUST00000114385.9
heterogeneous nuclear ribonucleoprotein M
chr11_-_102076028 0.85 ENSMUST00000107156.9
ENSMUST00000021297.6
LSM12 homolog
chr1_-_65102460 0.84 ENSMUST00000146122.2
ENSMUST00000045028.15
crystallin, gamma D
chr4_-_14621669 0.84 ENSMUST00000143105.2
solute carrier family 26, member 7
chr9_+_119170486 0.83 ENSMUST00000175743.8
ENSMUST00000176397.8
acetyl-Coenzyme A acyltransferase 1A
chr2_+_110551976 0.83 ENSMUST00000090332.5
mucin 15
chr5_-_138169253 0.78 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr9_+_40712562 0.75 ENSMUST00000117557.8
heat shock protein 8
chr6_-_41752111 0.74 ENSMUST00000214976.3
olfactory receptor 459
chr11_+_116734104 0.74 ENSMUST00000106370.10
methyltransferase like 23
chr11_+_58468556 0.72 ENSMUST00000203418.4
olfactory receptor 325
chrX_+_101847829 0.71 ENSMUST00000131451.2
DMRT-like family C1c1
chrX_+_162694397 0.70 ENSMUST00000140845.2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_99121822 0.69 ENSMUST00000103133.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr13_-_57043550 0.67 ENSMUST00000022023.13
ENSMUST00000174457.9
ENSMUST00000109871.8
transient receptor potential cation channel, subfamily C, member 7
chr5_+_33493529 0.67 ENSMUST00000202113.2
macrophage erythroblast attacher
chr10_+_127919142 0.66 ENSMUST00000026459.6
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr7_-_24371457 0.65 ENSMUST00000078001.7
testis expressed gene 101
chr13_-_58506890 0.64 ENSMUST00000225388.2
kinesin family member 27
chr4_-_41045381 0.64 ENSMUST00000054945.8
aquaporin 7
chr3_-_75072319 0.63 ENSMUST00000124618.2
zinc finger, B-box domain containing
chr14_+_26414422 0.63 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr12_-_99529767 0.61 ENSMUST00000176928.3
ENSMUST00000223484.2
forkhead box N3
chr2_-_111843053 0.61 ENSMUST00000213559.3
olfactory receptor 1310
chr18_+_36868084 0.60 ENSMUST00000007046.9
ENSMUST00000237870.2
transmembrane and coiled-coil domains 6
chr10_-_128885867 0.60 ENSMUST00000216460.2
olfactory receptor 765
chr2_+_110551685 0.58 ENSMUST00000111016.9
mucin 15
chr15_-_38079089 0.56 ENSMUST00000110336.4
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_112727089 0.56 ENSMUST00000063888.5
phospholipase D family, member 4
chr9_+_21634779 0.56 ENSMUST00000034713.9
low density lipoprotein receptor
chr7_+_29683373 0.55 ENSMUST00000148442.8
zinc finger protein 568
chr6_-_129752812 0.55 ENSMUST00000095409.3
killer cell lectin-like receptor subfamily H, member 1
chr9_+_20209828 0.55 ENSMUST00000215540.2
ENSMUST00000075717.7
olfactory receptor 873
chr9_+_39933648 0.55 ENSMUST00000059859.5
olfactory receptor 981
chr11_+_58668915 0.54 ENSMUST00000081533.5
olfactory receptor 315
chr11_+_69471185 0.53 ENSMUST00000171247.8
ENSMUST00000108658.10
ENSMUST00000005371.12
transformation related protein 53
chr6_-_68968278 0.51 ENSMUST00000197966.2
immunoglobulin kappa variable 4-81
chr2_+_110551927 0.50 ENSMUST00000111017.9
mucin 15
chr4_-_43710231 0.50 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr18_+_52958382 0.50 ENSMUST00000238707.2
predicted gene, 50457
chr2_-_87868043 0.47 ENSMUST00000129056.3
olfactory receptor 73
chr6_-_23650297 0.46 ENSMUST00000063548.4
ring finger protein 133
chr13_-_112698563 0.45 ENSMUST00000224510.2
interleukin 31 receptor A
chr11_+_5738480 0.45 ENSMUST00000109845.8
ENSMUST00000020769.14
ENSMUST00000102928.5
drebrin-like
chr7_-_102143980 0.44 ENSMUST00000058750.4
olfactory receptor 545
chr17_-_37591309 0.42 ENSMUST00000077585.3
olfactory receptor 99
chr11_+_101556367 0.41 ENSMUST00000039388.3
ADP-ribosylation factor-like 4D
chrX_+_113814692 0.41 ENSMUST00000059509.3
ubiquitin-conjugating enzyme E2D N-terminal like 1
chr7_+_45271229 0.41 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr6_+_40419797 0.41 ENSMUST00000038907.9
ENSMUST00000141490.2
WEE1 homolog 2 (S. pombe)
chr12_-_111150925 0.39 ENSMUST00000121608.2
RIKEN cDNA 4930595D18 gene
chr14_-_52704952 0.38 ENSMUST00000206520.3
olfactory receptor 1508
chr2_-_85193402 0.38 ENSMUST00000111597.3
olfactory receptor 988
chr11_-_95966407 0.37 ENSMUST00000107686.8
ENSMUST00000107684.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr2_-_111820618 0.36 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
olfactory receptor 1309
chr6_+_65019574 0.35 ENSMUST00000031984.9
ENSMUST00000205118.3
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_32178325 0.35 ENSMUST00000100194.10
ENSMUST00000131712.9
ENSMUST00000081670.14
ENSMUST00000147707.8
ENSMUST00000129193.3
golgi autoantigen, golgin subfamily a, 2
chr13_-_21900313 0.35 ENSMUST00000091756.2
H2B clustered histone 13
chr16_-_59166089 0.34 ENSMUST00000084791.4
olfactory receptor 206
chr2_+_68490186 0.34 ENSMUST00000055930.6
RIKEN cDNA 4932414N04 gene
chr5_-_137213788 0.34 ENSMUST00000239135.2
predicted gene, 31160
chrX_-_138683102 0.32 ENSMUST00000101217.4
ripply transcriptional repressor 1
chr14_-_50425655 0.32 ENSMUST00000205837.3
olfactory receptor 730
chr9_+_40092216 0.32 ENSMUST00000218134.2
ENSMUST00000216720.2
ENSMUST00000214763.2
olfactory receptor 986
chr12_-_83534482 0.31 ENSMUST00000177959.8
ENSMUST00000178756.8
D4, zinc and double PHD fingers, family 3
chrY_+_5656986 0.30 ENSMUST00000190391.2
predicted gene, 21854
chr14_+_62901114 0.30 ENSMUST00000171692.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr2_+_129965195 0.30 ENSMUST00000028888.5
transglutaminase 6
chr19_+_12364643 0.30 ENSMUST00000217062.3
ENSMUST00000216145.2
ENSMUST00000213657.2
olfactory receptor 1440
chr14_-_75991903 0.29 ENSMUST00000049168.9
component of oligomeric golgi complex 3
chr9_+_18944031 0.28 ENSMUST00000213018.3
olfactory receptor 835
chr2_-_90301592 0.28 ENSMUST00000111493.8
protein tyrosine phosphatase, receptor type, J

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.1 10.6 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
1.6 4.8 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
1.4 4.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.3 5.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.7 3.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.7 4.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.7 2.7 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.6 7.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.5 1.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 4.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 6.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 1.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.4 5.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.4 3.5 GO:0040031 snRNA modification(GO:0040031)
0.4 6.4 GO:0019374 galactolipid metabolic process(GO:0019374)
0.4 1.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 2.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 2.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 1.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 2.2 GO:0035633 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.3 2.3 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.3 74.1 GO:0002377 immunoglobulin production(GO:0002377)
0.3 5.1 GO:0007343 egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 1.6 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.3 7.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 3.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 0.7 GO:0097212 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.2 4.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.2 GO:0007386 compartment pattern specification(GO:0007386)
0.2 1.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 2.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.2 0.7 GO:0048822 enucleate erythrocyte development(GO:0048822)
0.2 0.4 GO:0035038 female pronucleus assembly(GO:0035038)
0.2 0.6 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.2 0.5 GO:1902689 negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
0.2 1.8 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 9.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.6 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 2.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.6 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.1 0.9 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.1 GO:0019532 oxalate transport(GO:0019532)
0.1 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 15.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.3 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1 4.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.9 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 3.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.9 GO:0016556 mRNA modification(GO:0016556)
0.1 0.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 1.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 2.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.3 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 2.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 3.4 GO:0007586 digestion(GO:0007586)
0.0 0.8 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 2.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0043415 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 2.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 4.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.6 3.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.5 2.1 GO:0008623 CHRAC(GO:0008623)
0.5 1.4 GO:0060187 cell pole(GO:0060187)
0.4 1.7 GO:0005608 laminin-3 complex(GO:0005608)
0.4 1.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 6.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 1.4 GO:0097452 GAIT complex(GO:0097452)
0.2 1.3 GO:0005899 insulin receptor complex(GO:0005899)
0.2 7.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.1 GO:0042382 paraspeckles(GO:0042382)
0.2 0.6 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 2.1 GO:0000801 central element(GO:0000801)
0.2 6.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 3.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.7 GO:0034657 GID complex(GO:0034657)
0.1 15.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 98.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.5 GO:0099738 cell cortex region(GO:0099738)
0.0 1.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 24.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 4.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0005174 CD40 receptor binding(GO:0005174)
0.7 5.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.7 2.7 GO:0070976 TIR domain binding(GO:0070976)
0.6 7.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 3.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.5 2.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 4.8 GO:0004064 arylesterase activity(GO:0004064)
0.4 5.2 GO:0050700 CARD domain binding(GO:0050700)
0.4 9.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 6.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 1.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 1.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 2.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 2.4 GO:0017040 ceramidase activity(GO:0017040)
0.3 0.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.3 0.8 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.2 1.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 1.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.2 0.7 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 1.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 33.6 GO:0003823 antigen binding(GO:0003823)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 4.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 2.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 2.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 11.3 GO:0002020 protease binding(GO:0002020)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 3.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 3.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 4.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 3.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 4.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 6.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 3.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 7.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 10.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 7.0 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 2.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 4.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 5.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation