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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxb5

Z-value: 0.79

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Transcription factors associated with Hoxb5

Gene Symbol Gene ID Gene Info
Hoxb5
ENSMUSG00000038700.5 Hoxb5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb5mm39_v1_chr11_+_96194333_96194378-0.412.9e-04Click!

Activity profile of Hoxb5 motif

Sorted Z-values of Hoxb5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_125609440 8.02 ENSMUST00000031446.7
Tmem132b
transmembrane protein 132B
chr2_-_151474391 7.24 ENSMUST00000137936.2
ENSMUST00000146172.8
ENSMUST00000094456.10
ENSMUST00000148755.8
ENSMUST00000109875.8
ENSMUST00000028951.14
ENSMUST00000109877.10
Snph
syntaphilin
chr1_-_75240551 7.04 ENSMUST00000186178.7
ENSMUST00000189769.7
ENSMUST00000027404.12
Ptprn
protein tyrosine phosphatase, receptor type, N
chr9_-_35469818 6.35 ENSMUST00000034612.7
Ddx25
DEAD box helicase 25
chr17_-_57394718 6.30 ENSMUST00000071135.6
Tubb4a
tubulin, beta 4A class IVA
chr7_-_44861235 5.81 ENSMUST00000210741.2
ENSMUST00000209466.2
Dkkl1
dickkopf-like 1
chr19_-_45804446 5.68 ENSMUST00000079431.10
ENSMUST00000026247.13
ENSMUST00000162528.9
Kcnip2
Kv channel-interacting protein 2
chr2_+_102489558 5.24 ENSMUST00000111213.8
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_+_125608838 4.85 ENSMUST00000185104.2
Tmem132b
transmembrane protein 132B
chr7_+_3439144 4.73 ENSMUST00000182222.8
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr10_-_80850712 4.66 ENSMUST00000126317.2
ENSMUST00000092285.10
ENSMUST00000117805.8
Gng7
guanine nucleotide binding protein (G protein), gamma 7
chr15_-_95553841 4.62 ENSMUST00000054244.7
Dbx2
developing brain homeobox 2
chr12_+_88689638 4.59 ENSMUST00000190626.7
ENSMUST00000167103.8
Nrxn3
neurexin III
chr5_-_103359117 4.42 ENSMUST00000112846.8
ENSMUST00000170792.9
ENSMUST00000112847.9
ENSMUST00000238446.3
ENSMUST00000133069.8
Mapk10
mitogen-activated protein kinase 10
chr16_-_44153498 4.15 ENSMUST00000047446.13
Sidt1
SID1 transmembrane family, member 1
chr7_-_108682491 4.00 ENSMUST00000120876.2
ENSMUST00000055993.13
Ric3
RIC3 acetylcholine receptor chaperone
chr13_+_88969591 3.77 ENSMUST00000118731.8
ENSMUST00000081769.13
Edil3
EGF-like repeats and discoidin I-like domains 3
chr13_+_88969725 3.59 ENSMUST00000043111.7
Edil3
EGF-like repeats and discoidin I-like domains 3
chr6_-_113478779 3.51 ENSMUST00000101059.4
ENSMUST00000204268.3
ENSMUST00000205170.2
ENSMUST00000205075.2
ENSMUST00000204134.3
Prrt3
proline-rich transmembrane protein 3
chr7_-_123099672 3.45 ENSMUST00000042470.14
ENSMUST00000128217.2
Zkscan2
zinc finger with KRAB and SCAN domains 2
chr7_+_16609227 3.43 ENSMUST00000108493.3
Dact3
dishevelled-binding antagonist of beta-catenin 3
chr6_-_18514801 3.28 ENSMUST00000090601.12
Cttnbp2
cortactin binding protein 2
chr9_-_52590686 3.26 ENSMUST00000098768.3
ENSMUST00000213843.2
AI593442
expressed sequence AI593442
chr1_-_193052533 3.19 ENSMUST00000169907.8
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_+_80136830 3.11 ENSMUST00000140828.8
ENSMUST00000138909.8
Apc2
APC regulator of WNT signaling pathway 2
chr1_-_193052568 2.98 ENSMUST00000016323.11
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chrX_-_164110372 2.88 ENSMUST00000058787.9
Glra2
glycine receptor, alpha 2 subunit
chr18_-_16942289 2.87 ENSMUST00000025166.14
Cdh2
cadherin 2
chr12_-_79027531 2.62 ENSMUST00000174072.8
Tmem229b
transmembrane protein 229B
chr16_-_44153288 2.56 ENSMUST00000136381.8
Sidt1
SID1 transmembrane family, member 1
chr12_-_36092475 2.52 ENSMUST00000020896.17
Tspan13
tetraspanin 13
chr1_+_74583504 2.44 ENSMUST00000027362.14
Plcd4
phospholipase C, delta 4
chr5_+_143869875 2.34 ENSMUST00000166847.8
Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr8_-_71303383 2.32 ENSMUST00000212084.2
Kcnn1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr6_+_121613177 2.29 ENSMUST00000032203.9
A2m
alpha-2-macroglobulin
chrX_+_149829131 2.22 ENSMUST00000112685.8
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr10_-_127047396 2.20 ENSMUST00000013970.9
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_-_23990512 2.15 ENSMUST00000226460.2
Flywch1
FLYWCH-type zinc finger 1
chr16_+_16888145 2.06 ENSMUST00000232574.2
Ypel1
yippee like 1
chr17_-_23990479 2.01 ENSMUST00000086325.13
Flywch1
FLYWCH-type zinc finger 1
chr1_+_132131590 1.97 ENSMUST00000185223.2
Lemd1
LEM domain containing 1
chr16_+_16888084 1.91 ENSMUST00000231514.2
Ypel1
yippee like 1
chrX_+_20554193 1.84 ENSMUST00000115364.8
Cdk16
cyclin-dependent kinase 16
chr17_-_80885197 1.83 ENSMUST00000234602.2
Cdkl4
cyclin-dependent kinase-like 4
chr8_+_95807814 1.79 ENSMUST00000034239.9
Katnb1
katanin p80 (WD40-containing) subunit B 1
chrX_-_133012600 1.76 ENSMUST00000033610.13
Nox1
NADPH oxidase 1
chr11_-_69088635 1.62 ENSMUST00000094078.4
ENSMUST00000021262.10
Alox8
arachidonate 8-lipoxygenase
chr2_+_158509039 1.61 ENSMUST00000045503.11
Ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chrX_+_106860083 1.54 ENSMUST00000143975.8
ENSMUST00000144695.8
ENSMUST00000167154.2
Tent5d
terminal nucleotidyltransferase 5D
chr18_-_61840654 1.53 ENSMUST00000025472.7
Pcyox1l
prenylcysteine oxidase 1 like
chr2_-_153067297 1.51 ENSMUST00000099194.4
Tspyl3
TSPY-like 3
chrX_-_71699740 1.51 ENSMUST00000055966.13
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr8_-_123768984 1.47 ENSMUST00000212937.2
Ankrd11
ankyrin repeat domain 11
chr9_+_8900460 1.44 ENSMUST00000070463.10
ENSMUST00000098986.4
Pgr
progesterone receptor
chr7_-_126807581 1.43 ENSMUST00000120705.3
Tbc1d10b
TBC1 domain family, member 10b
chr5_+_112597272 1.42 ENSMUST00000100882.3
Gm6588
predicted gene 6588
chr17_-_48002328 1.41 ENSMUST00000152214.4
ENSMUST00000113299.6
Prickle4
prickle planar cell polarity protein 4
chr8_-_25086976 1.38 ENSMUST00000033956.7
Ido1
indoleamine 2,3-dioxygenase 1
chr16_+_16887991 1.27 ENSMUST00000232258.2
Ypel1
yippee like 1
chr8_+_21382681 1.24 ENSMUST00000098908.4
Defb33
defensin beta 33
chr2_-_164585102 1.21 ENSMUST00000103096.10
Wfdc3
WAP four-disulfide core domain 3
chr7_-_86044743 1.16 ENSMUST00000053958.6
Olfr303
olfactory receptor 303
chr12_-_79030250 1.16 ENSMUST00000070174.14
Tmem229b
transmembrane protein 229B
chr8_-_26087475 1.16 ENSMUST00000210810.2
ENSMUST00000210616.2
ENSMUST00000079160.8
Letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr7_+_86175967 1.13 ENSMUST00000071112.4
Olfr297
olfactory receptor 297
chrX_+_7688528 1.03 ENSMUST00000009875.5
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr7_-_133310687 1.01 ENSMUST00000106146.8
Uros
uroporphyrinogen III synthase
chr2_-_115896279 0.95 ENSMUST00000110907.8
ENSMUST00000110908.9
Meis2
Meis homeobox 2
chr9_+_107277242 0.92 ENSMUST00000166799.8
ENSMUST00000170737.3
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr7_-_133310779 0.92 ENSMUST00000124759.2
ENSMUST00000106144.8
ENSMUST00000106145.10
Uros
uroporphyrinogen III synthase
chr7_-_30850429 0.91 ENSMUST00000085636.13
ENSMUST00000001280.14
Gramd1a
GRAM domain containing 1A
chr4_-_149222057 0.89 ENSMUST00000030813.10
Cenps
centromere protein S
chr19_-_7460550 0.87 ENSMUST00000088169.7
Rtn3
reticulon 3
chr8_-_123768759 0.84 ENSMUST00000098334.13
Ankrd11
ankyrin repeat domain 11
chr14_-_40726472 0.83 ENSMUST00000153830.8
Prxl2a
peroxiredoxin like 2A
chr8_-_26087552 0.79 ENSMUST00000210234.2
ENSMUST00000211422.2
Letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_+_125089110 0.79 ENSMUST00000082122.14
Dut
deoxyuridine triphosphatase
chr16_-_64422716 0.77 ENSMUST00000209382.3
Csnka2ip
casein kinase 2, alpha prime interacting protein
chr2_+_152804405 0.75 ENSMUST00000099197.9
ENSMUST00000103155.10
Ttll9
tubulin tyrosine ligase-like family, member 9
chr11_-_95966477 0.70 ENSMUST00000090541.12
Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr9_+_107277058 0.69 ENSMUST00000085092.12
ENSMUST00000164988.9
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr4_-_149221998 0.67 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
Cenps
centromere protein S
chr8_-_86567506 0.64 ENSMUST00000034140.9
Itfg1
integrin alpha FG-GAP repeat containing 1
chr19_-_7460600 0.64 ENSMUST00000235593.2
ENSMUST00000088171.12
ENSMUST00000065304.13
ENSMUST00000025667.14
Rtn3
reticulon 3
chrX_-_103244703 0.62 ENSMUST00000087879.11
Nexmif
neurite extension and migration factor
chr13_-_31158031 0.61 ENSMUST00000021785.8
Exoc2
exocyst complex component 2
chr9_+_20492593 0.54 ENSMUST00000115557.10
Zfp846
zinc finger protein 846
chr9_-_19163273 0.53 ENSMUST00000214019.2
ENSMUST00000214267.2
Olfr843
olfactory receptor 843
chr8_+_124059414 0.45 ENSMUST00000010298.7
Spire2
spire type actin nucleation factor 2
chr7_+_127441119 0.43 ENSMUST00000121705.8
Stx4a
syntaxin 4A (placental)
chr1_+_92878566 0.41 ENSMUST00000185421.2
Gpr35
G protein-coupled receptor 35
chr7_+_127440924 0.37 ENSMUST00000033075.14
Stx4a
syntaxin 4A (placental)
chr8_-_129525175 0.36 ENSMUST00000195093.2
Gm3952
predicted gene 3952
chr2_-_166904625 0.35 ENSMUST00000128676.2
Znfx1
zinc finger, NFX1-type containing 1
chr2_+_26863494 0.35 ENSMUST00000102891.4
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr2_-_5867734 0.34 ENSMUST00000071016.3
Gm13199
predicted gene 13199
chr1_-_166237341 0.32 ENSMUST00000135673.8
ENSMUST00000169324.8
ENSMUST00000128861.3
Pogk
pogo transposable element with KRAB domain
chr13_+_23879775 0.31 ENSMUST00000041052.5
H1f6
H1.6 linker histone, cluster member
chr7_-_45116316 0.29 ENSMUST00000033093.10
Bax
BCL2-associated X protein
chr13_-_14237958 0.28 ENSMUST00000223174.2
Ggps1
geranylgeranyl diphosphate synthase 1
chr6_+_48906825 0.26 ENSMUST00000031837.8
Doxl1
diamine oxidase-like protein 1
chr14_-_64225223 0.24 ENSMUST00000022532.6
4930578I06Rik
RIKEN cDNA 4930578I06 gene
chr2_+_26863428 0.23 ENSMUST00000014996.14
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr15_+_44482545 0.22 ENSMUST00000227691.2
Ebag9
estrogen receptor-binding fragment-associated gene 9
chrX_-_103244784 0.18 ENSMUST00000118314.8
Nexmif
neurite extension and migration factor
chr10_-_61979685 0.18 ENSMUST00000141724.8
ENSMUST00000150057.2
Fam241b
family with sequence similarity 241, member B
chr1_-_74583434 0.15 ENSMUST00000189257.7
Usp37
ubiquitin specific peptidase 37
chr7_-_103710652 0.14 ENSMUST00000074064.5
4930516K23Rik
RIKEN cDNA 4930516K23 gene
chr16_+_32315090 0.12 ENSMUST00000231510.2
Zdhhc19
zinc finger, DHHC domain containing 19
chr6_-_128339775 0.12 ENSMUST00000112152.8
ENSMUST00000057421.15
ENSMUST00000112151.2
Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr5_+_117271632 0.12 ENSMUST00000179276.8
ENSMUST00000092889.12
ENSMUST00000145640.8
Taok3
TAO kinase 3
chr6_+_86415342 0.12 ENSMUST00000050497.14
ENSMUST00000203568.3
C87436
expressed sequence C87436
chr14_+_31881822 0.11 ENSMUST00000163336.8
ENSMUST00000169722.8
ENSMUST00000168385.8
Ncoa4
nuclear receptor coactivator 4
chr7_-_45116216 0.10 ENSMUST00000210392.2
ENSMUST00000211365.2
Bax
BCL2-associated X protein
chr13_-_14237980 0.05 ENSMUST00000222687.2
ENSMUST00000221338.2
ENSMUST00000221713.2
ENSMUST00000170957.3
Ggps1
geranylgeranyl diphosphate synthase 1
chr5_-_108956716 0.05 ENSMUST00000233055.2
ENSMUST00000232952.2
ENSMUST00000233745.2
ENSMUST00000172140.3
Vmn2r8
vomeronasal 2, receptor 8
chr7_-_140480314 0.04 ENSMUST00000026561.10
Cox8b
cytochrome c oxidase subunit 8B
chr3_-_89067462 0.02 ENSMUST00000029686.4
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.8 2.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7 5.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 1.9 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.6 4.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 6.7 GO:0033227 dsRNA transport(GO:0033227)
0.5 1.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.5 4.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.5 1.4 GO:0036269 swimming behavior(GO:0036269)
0.4 1.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.4 7.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.4 2.9 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.4 1.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 1.6 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.4 1.4 GO:1904708 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
0.3 1.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.3 6.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 2.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.3 0.8 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 5.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 0.8 GO:0006226 dUMP biosynthetic process(GO:0006226) pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 2.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 4.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 1.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 1.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.1 4.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 6.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.6 GO:0001927 exocyst assembly(GO:0001927)
0.1 1.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 4.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 7.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.1 5.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 2.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.8 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 7.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 6.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 3.4 GO:0006813 potassium ion transport(GO:0006813)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.3 GO:0033269 internode region of axon(GO:0033269)
0.4 1.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 6.0 GO:0016342 catenin complex(GO:0016342)
0.3 6.4 GO:0033391 chromatoid body(GO:0033391)
0.2 1.6 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 17.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0043219 lateral loop(GO:0043219)
0.1 4.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 6.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 8.1 GO:0043679 axon terminus(GO:0043679)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 5.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 4.4 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.1 6.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9 4.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.9 5.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 2.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.7 2.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 1.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.4 2.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 3.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 1.9 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 1.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 2.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 3.4 GO:0070097 delta-catenin binding(GO:0070097)
0.2 7.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 7.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 5.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 4.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 6.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 7.0 GO:0030507 spectrin binding(GO:0030507)
0.1 6.4 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 6.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 7.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 2.0 GO:0043022 ribosome binding(GO:0043022)
0.0 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 4.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling