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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxb8_Pdx1

Z-value: 1.35

Motif logo

Transcription factors associated with Hoxb8_Pdx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000056648.6 Hoxb8
ENSMUSG00000029644.8 Pdx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pdx1mm39_v1_chr5_+_147206769_1472069120.152.2e-01Click!
Hoxb8mm39_v1_chr11_+_96173475_961735510.028.5e-01Click!

Activity profile of Hoxb8_Pdx1 motif

Sorted Z-values of Hoxb8_Pdx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb8_Pdx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_130633776 26.59 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr1_+_130754413 24.43 ENSMUST00000027675.14
ENSMUST00000133792.8
polymeric immunoglobulin receptor
chr15_+_31224616 13.21 ENSMUST00000186547.7
death-associated protein
chr15_+_31225302 12.09 ENSMUST00000186425.7
death-associated protein
chr14_+_47611270 11.33 ENSMUST00000142734.8
ENSMUST00000150290.9
ENSMUST00000226585.2
ENSMUST00000144794.2
ENSMUST00000146468.4
lectin, galactose binding, soluble 3
chr11_-_58504307 11.32 ENSMUST00000048801.8
LY6/PLAUR domain containing 8 like
chr13_+_4109566 11.22 ENSMUST00000041768.7
aldo-keto reductase family 1, member C14
chr6_-_52141796 11.03 ENSMUST00000014848.11
homeobox A2
chr8_-_110765983 10.74 ENSMUST00000109222.4
carbohydrate sulfotransferase 4
chr16_-_18904240 10.55 ENSMUST00000103746.3
immunoglobulin lambda variable 1
chr13_-_24098981 9.70 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr15_+_31224460 9.65 ENSMUST00000044524.16
death-associated protein
chr15_+_31224555 9.12 ENSMUST00000186109.2
death-associated protein
chr13_-_24098951 9.03 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr2_-_84605764 8.72 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84605732 8.19 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_-_36312482 7.99 ENSMUST00000056946.8
neuralized E3 ubiquitin protein ligase 3
chr11_+_96242422 7.83 ENSMUST00000100523.7
homeobox B2
chr10_+_101994719 7.45 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
MGAT4 family, member C
chr6_+_128639342 7.28 ENSMUST00000032518.7
ENSMUST00000204416.2
C-type lectin domain family 2, member h
chr2_+_122479770 7.12 ENSMUST00000047498.15
ENSMUST00000110512.4
expressed sequence AA467197
chr6_+_41928559 6.71 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr10_+_101994841 6.41 ENSMUST00000020039.13
MGAT4 family, member C
chr1_+_88062508 6.41 ENSMUST00000113134.8
ENSMUST00000140092.8
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr1_+_88030951 6.24 ENSMUST00000113135.6
ENSMUST00000113138.8
UDP glucuronosyltransferase 1 family, polypeptide A7C
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr19_-_4548602 6.23 ENSMUST00000048482.8
RIKEN cDNA 2010003K11 gene
chr19_+_30210320 6.09 ENSMUST00000025797.7
mannose-binding lectin (protein C) 2
chr4_-_35157405 5.46 ENSMUST00000102975.10
MOB kinase activator 3B
chr2_+_122478882 5.13 ENSMUST00000142767.8
expressed sequence AA467197
chr7_-_46392403 5.09 ENSMUST00000128088.4
serum amyloid A 1
chr8_-_5155347 5.07 ENSMUST00000023835.3
solute carrier family 10, member 2
chr5_+_92831150 4.93 ENSMUST00000113055.9
shroom family member 3
chr6_-_34965339 4.92 ENSMUST00000201355.4
solute carrier family 23 member 4
chr19_-_24178000 4.88 ENSMUST00000233658.3
tight junction protein 2
chr13_+_94954202 4.85 ENSMUST00000220825.2
tubulin cofactor A
chr8_-_4829519 4.78 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr2_+_125876566 4.78 ENSMUST00000064794.14
fibroblast growth factor 7
chr2_+_74512638 4.77 ENSMUST00000142312.3
homeobox D11
chr16_+_96162854 4.73 ENSMUST00000113794.8
immunoglobulin superfamily, member 5
chr3_-_20329823 4.72 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr5_+_92831468 4.61 ENSMUST00000168878.8
shroom family member 3
chr13_+_4283729 4.48 ENSMUST00000081326.7
aldo-keto reductase family 1, member C19
chr8_-_4829473 4.46 ENSMUST00000207262.2
Shc SH2-domain binding protein 1
chr3_-_65299967 4.44 ENSMUST00000119896.2
signal sequence receptor, gamma
chr6_-_119365632 4.40 ENSMUST00000169744.8
adiponectin receptor 2
chr4_-_150087587 4.14 ENSMUST00000084117.13
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr12_-_115172211 4.09 ENSMUST00000103526.3
immunoglobulin heavy variable 1-55
chr4_+_101574601 4.09 ENSMUST00000102777.10
ENSMUST00000106921.9
ENSMUST00000037552.10
ENSMUST00000145024.2
leptin receptor
chr5_-_87288177 4.08 ENSMUST00000067790.7
UDP glucuronosyltransferase 2 family, polypeptide B5
chr10_+_96453408 4.07 ENSMUST00000218953.2
BTG anti-proliferation factor 1
chr19_-_39729431 4.07 ENSMUST00000099472.4
cytochrome P450, family 2, subfamily c, polypeptide 68
chr3_+_57332735 4.05 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr6_-_68609426 3.95 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr5_+_93045837 3.94 ENSMUST00000113051.9
shroom family member 3
chr13_+_4099001 3.91 ENSMUST00000118717.10
aldo-keto reductase family 1, member C14
chr2_+_125876883 3.89 ENSMUST00000110442.2
fibroblast growth factor 7
chr6_-_136758716 3.86 ENSMUST00000078095.11
ENSMUST00000032338.10
guanylate cyclase 2c
chr4_+_148985584 3.84 ENSMUST00000147270.2
castor zinc finger 1
chr6_-_3399451 3.83 ENSMUST00000120087.6
sterile alpha motif domain containing 9-like
chr6_-_124519240 3.80 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr3_-_65300000 3.76 ENSMUST00000029414.12
signal sequence receptor, gamma
chr18_-_32271224 3.71 ENSMUST00000234657.2
ENSMUST00000234386.2
ENSMUST00000234651.2
protein C
chr11_-_84058292 3.56 ENSMUST00000050771.8
predicted gene 11437
chr5_-_88675700 3.50 ENSMUST00000087033.6
immunoglobulin joining chain
chr5_-_113369096 3.42 ENSMUST00000211733.2
RIKEN cDNA 2900026A02 gene
chr1_+_88093726 3.35 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr12_-_115722081 3.28 ENSMUST00000103541.3
immunoglobulin heavy variable 1-72
chr9_-_70842090 3.25 ENSMUST00000034731.10
lipase, hepatic
chr9_-_31043076 3.22 ENSMUST00000034478.3
suppression of tumorigenicity 14 (colon carcinoma)
chr15_+_101310283 3.21 ENSMUST00000068904.9
keratin 7
chr3_-_157630690 3.15 ENSMUST00000118539.2
cystathionase (cystathionine gamma-lyase)
chr3_+_132335704 3.12 ENSMUST00000212594.2
GIMAP family P-loop NTPase domain containing 1
chr8_-_110766009 3.09 ENSMUST00000212934.2
carbohydrate sulfotransferase 4
chr3_-_88417251 3.07 ENSMUST00000149068.2
lamin A
chr16_+_22769822 3.07 ENSMUST00000023590.9
histidine-rich glycoprotein
chr6_+_116627567 3.04 ENSMUST00000067354.10
ENSMUST00000178241.4
DEPP1 autophagy regulator
chr16_-_19079594 3.04 ENSMUST00000103752.3
ENSMUST00000197518.2
immunoglobulin lambda variable 2
chr9_-_76474374 3.04 ENSMUST00000183437.8
family with sequence similarity 83, member B
chr6_-_52203146 3.04 ENSMUST00000114425.3
homeobox A9
chr2_-_74489763 3.03 ENSMUST00000173623.2
ENSMUST00000001867.13
even-skipped homeobox 2
chr17_-_41225241 3.03 ENSMUST00000166343.3
glycine-N-acyltransferase-like 3
chr6_-_52185674 3.01 ENSMUST00000062829.9
homeobox A6
chr3_-_107851021 2.99 ENSMUST00000106684.8
ENSMUST00000106685.9
glutathione S-transferase, mu 6
chr12_-_103923145 2.97 ENSMUST00000085054.5
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr12_-_103829810 2.95 ENSMUST00000085056.8
ENSMUST00000072876.12
ENSMUST00000124717.2
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr1_-_45542442 2.92 ENSMUST00000086430.5
collagen, type V, alpha 2
chr17_+_37504783 2.91 ENSMUST00000038844.7
ubiquitin D
chr3_-_82957104 2.82 ENSMUST00000048246.5
fibrinogen beta chain
chr13_+_19398273 2.75 ENSMUST00000103558.3
T cell receptor gamma, constant 1
chr6_+_142244145 2.63 ENSMUST00000041993.3
islet amyloid polypeptide
chr9_-_70841881 2.62 ENSMUST00000214995.2
lipase, hepatic
chr9_-_85209340 2.61 ENSMUST00000187711.2
terminal nucleotidyltransferase 5A
chr14_+_74973081 2.59 ENSMUST00000177283.8
esterase D/formylglutathione hydrolase
chr9_-_85209162 2.58 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr6_+_124281607 2.56 ENSMUST00000032234.5
ENSMUST00000112541.8
CD163 antigen
chr16_+_78727829 2.56 ENSMUST00000114216.2
ENSMUST00000069148.13
ENSMUST00000023568.14
chondrolectin
chr1_+_87983099 2.54 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr3_-_107850707 2.54 ENSMUST00000106681.3
glutathione S-transferase, mu 6
chr5_-_130053120 2.52 ENSMUST00000161640.8
ENSMUST00000161884.2
ENSMUST00000161094.8
argininosuccinate lyase
chr11_-_69439934 2.51 ENSMUST00000108659.2
dynein, axonemal, heavy chain 2
chr5_-_87074380 2.50 ENSMUST00000031183.3
UDP glucuronosyltransferase 2 family, polypeptide B1
chr1_-_57011595 2.49 ENSMUST00000042857.14
special AT-rich sequence binding protein 2
chr1_-_10038030 2.46 ENSMUST00000185184.2
transcription factor 24
chr6_-_3494587 2.45 ENSMUST00000049985.15
HEPACAM family member 2
chr3_+_132335575 2.44 ENSMUST00000212804.2
ENSMUST00000212852.2
GIMAP family P-loop NTPase domain containing 1
chr1_-_39616445 2.44 ENSMUST00000062525.11
ring finger protein 149
chr17_-_71153283 2.42 ENSMUST00000156484.2
TGFB-induced factor homeobox 1
chr10_+_5543769 2.40 ENSMUST00000051809.10
myc target 1
chr13_+_23991010 2.39 ENSMUST00000006786.11
ENSMUST00000099697.3
solute carrier family 17 (sodium phosphate), member 2
chr16_+_22769844 2.35 ENSMUST00000232422.2
histidine-rich glycoprotein
chr13_+_94219934 2.33 ENSMUST00000156071.2
lipoma HMGIC fusion partner-like 2
chr7_+_46401214 2.32 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr17_-_71309815 2.31 ENSMUST00000123686.8
myosin, light chain 12A, regulatory, non-sarcomeric
chr16_-_56533179 2.31 ENSMUST00000136394.8
Trk-fused gene
chr2_+_152873772 2.31 ENSMUST00000037235.7
X-linked Kx blood group related 7
chr17_-_35081129 2.27 ENSMUST00000154526.8
complement factor B
chr5_+_30360246 2.27 ENSMUST00000026841.15
ENSMUST00000123980.8
ENSMUST00000114783.6
ENSMUST00000114786.8
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr5_-_30360113 2.26 ENSMUST00000156859.3
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chr1_-_120198804 2.23 ENSMUST00000112641.8
STEAP family member 3
chr11_-_99482165 2.22 ENSMUST00000104930.2
keratin associated protein 1-3
chr2_+_69210775 2.20 ENSMUST00000063690.4
dehydrogenase/reductase (SDR family) member 9
chr1_-_126758369 2.19 ENSMUST00000112583.8
ENSMUST00000094609.10
NCK-associated protein 5
chr18_-_66155651 2.18 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr2_-_69036489 2.18 ENSMUST00000127243.8
ENSMUST00000149643.2
ENSMUST00000167875.9
ENSMUST00000005365.15
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr11_+_96214078 2.17 ENSMUST00000093944.10
homeobox B3
chr5_-_87572060 2.16 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chr12_-_115425105 2.14 ENSMUST00000103532.3
immunoglobulin heavy variable 1-62-3
chr3_-_51184730 2.14 ENSMUST00000195432.2
ENSMUST00000091144.11
ENSMUST00000156983.3
E74-like factor 2
chr3_+_85948030 2.11 ENSMUST00000238545.2
SH3 domain protein D19
chr10_+_101517348 2.06 ENSMUST00000179929.8
ENSMUST00000219195.2
ENSMUST00000127504.9
MGAT4 family, member C
chr3_+_82915031 2.05 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr18_+_43897354 2.03 ENSMUST00000187157.7
ENSMUST00000043803.13
ENSMUST00000189750.2
secretoglobin, family 3A, member 2
chr2_-_38604503 2.01 ENSMUST00000028084.5
nuclear receptor subfamily 5, group A, member 1
chr19_+_39980868 2.00 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_-_66211842 2.00 ENSMUST00000200852.4
RNA binding motif protein 47
chr3_+_144824644 1.99 ENSMUST00000199124.5
outer dense fiber of sperm tails 2-like
chr1_-_149798090 1.95 ENSMUST00000111926.9
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_-_21851827 1.92 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
tetraspanin 12
chr3_+_85947806 1.88 ENSMUST00000238222.2
SH3 domain protein D19
chr1_-_164763091 1.87 ENSMUST00000027860.8
chemokine (C motif) ligand 1
chr2_-_155668567 1.87 ENSMUST00000109638.2
ENSMUST00000134278.2
eukaryotic translation initiation factor 6
chr17_+_79919267 1.84 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr17_-_35081456 1.83 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr2_-_69036472 1.83 ENSMUST00000112320.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr4_+_109092610 1.83 ENSMUST00000106628.8
calreticulin 4
chr18_+_46983105 1.81 ENSMUST00000025358.4
ENSMUST00000234519.2
laeverin
chr14_-_59602882 1.81 ENSMUST00000160425.8
ENSMUST00000095157.11
PHD finger protein 11D
chr8_-_45747883 1.79 ENSMUST00000026907.6
kallikrein B, plasma 1
chrX_-_105055486 1.77 ENSMUST00000238718.2
ENSMUST00000033583.14
ENSMUST00000151689.9
magnesium transporter 1
chr1_+_87983189 1.77 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr6_+_116627635 1.75 ENSMUST00000204555.2
DEPP1 autophagy regulator
chr14_+_55797468 1.75 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr1_-_57010921 1.73 ENSMUST00000114415.10
special AT-rich sequence binding protein 2
chr7_-_37472979 1.72 ENSMUST00000176534.8
zinc finger protein 536
chr1_-_126758520 1.71 ENSMUST00000162646.8
NCK-associated protein 5
chr14_+_26722319 1.68 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr1_+_118555668 1.65 ENSMUST00000027629.10
transcription factor CP2-like 1
chr10_+_33733706 1.65 ENSMUST00000218204.2
sulfotransferase family 3A, member 1
chr19_-_32080496 1.64 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr9_+_35334878 1.62 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr1_-_162726053 1.62 ENSMUST00000143123.3
flavin containing monooxygenase 2
chr8_-_84059048 1.61 ENSMUST00000177594.8
ENSMUST00000053902.4
ELMO/CED-12 domain containing 2
chr10_+_100428212 1.61 ENSMUST00000187119.7
ENSMUST00000188736.7
ENSMUST00000191336.7
RIKEN cDNA 1700017N19 gene
chr8_-_106198112 1.60 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr14_+_55797443 1.55 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr2_-_84255602 1.55 ENSMUST00000074262.9
calcitonin receptor-like
chr1_+_58752415 1.54 ENSMUST00000114309.8
ENSMUST00000069333.8
CASP8 and FADD-like apoptosis regulator
chr5_+_65920861 1.49 ENSMUST00000201489.4
NEDD4 binding protein 2
chr18_-_35631914 1.49 ENSMUST00000236007.2
ENSMUST00000237896.2
ENSMUST00000235778.2
ENSMUST00000235524.2
ENSMUST00000235691.2
ENSMUST00000235619.2
ENSMUST00000025215.10
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr2_+_125701054 1.48 ENSMUST00000028636.13
ENSMUST00000125084.8
galactokinase 2
chr16_+_90535212 1.42 ENSMUST00000038197.3
melanocortin 2 receptor accessory protein
chr14_+_55797934 1.41 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr14_+_54433524 1.40 ENSMUST00000103718.2
T cell receptor alpha joining 23
chr1_-_65071897 1.38 ENSMUST00000162800.8
ENSMUST00000069142.12
aldo-keto reductase family 1, member C-like
chr5_-_125418107 1.38 ENSMUST00000111390.8
ENSMUST00000086075.13
scavenger receptor class B, member 1
chr7_-_49286594 1.38 ENSMUST00000032717.7
developing brain homeobox 1
chr10_-_128579879 1.38 ENSMUST00000026414.9
diacylglycerol kinase, alpha
chr1_+_90981144 1.36 ENSMUST00000068167.13
ENSMUST00000097649.10
ENSMUST00000186762.7
ENSMUST00000097650.10
leucine rich repeat (in FLII) interacting protein 1
chrM_+_11735 1.35 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr12_-_103871146 1.35 ENSMUST00000074051.6
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr1_-_118981069 1.32 ENSMUST00000161301.8
ENSMUST00000161451.8
ENSMUST00000162607.2
GLI-Kruppel family member GLI2
chr17_+_24645615 1.32 ENSMUST00000234304.2
ENSMUST00000024946.7
ENSMUST00000234150.2
enoyl-Coenzyme A delta isomerase 1
chr9_+_54441404 1.30 ENSMUST00000118413.3
SH2 domain containing 7
chr16_+_24540599 1.30 ENSMUST00000115314.4
LIM domain containing preferred translocation partner in lipoma
chr17_-_35023521 1.29 ENSMUST00000025223.9
cytochrome P450, family 21, subfamily a, polypeptide 1
chr6_-_51989456 1.29 ENSMUST00000078214.8
ENSMUST00000204778.3
src family associated phosphoprotein 2
chr19_-_3625698 1.27 ENSMUST00000172362.3
ENSMUST00000025846.16
ENSMUST00000226109.2
ENSMUST00000113997.9
protein phosphatase 6, regulatory subunit 3
chr19_+_11674413 1.27 ENSMUST00000069760.13
ENSMUST00000119053.3
oocyte secreted protein 3
chr10_-_41585293 1.26 ENSMUST00000019955.16
ENSMUST00000099932.10
coiled-coil domain containing 162
chr3_-_51184895 1.25 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr2_-_125701059 1.25 ENSMUST00000110463.8
ENSMUST00000028635.6
COP9 signalosome subunit 2
chr11_-_106890307 1.22 ENSMUST00000018506.13
karyopherin (importin) alpha 2
chr8_-_25085654 1.19 ENSMUST00000110667.8
indoleamine 2,3-dioxygenase 1
chr1_-_37575313 1.19 ENSMUST00000042161.15
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr4_+_138503046 1.18 ENSMUST00000030528.9
phospholipase A2, group IID
chr2_+_36120438 1.18 ENSMUST00000062069.6
prostaglandin-endoperoxide synthase 1
chr11_+_46701619 1.17 ENSMUST00000068877.7
T cell immunoglobulin and mucin domain containing 4
chr12_+_105569344 1.16 ENSMUST00000182899.2
ENSMUST00000183086.2
bradykinin receptor, beta 1
chr14_+_54429757 1.16 ENSMUST00000103714.2
T cell receptor alpha joining 27
chr12_-_16850887 1.15 ENSMUST00000161998.3
gene regulated by estrogen in breast cancer protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.4 GO:0002414 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
5.6 16.9 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
4.6 13.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
3.1 18.9 GO:0021569 rhombomere 3 development(GO:0021569)
2.9 8.7 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
2.2 8.9 GO:2001189 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
2.1 6.2 GO:0006711 estrogen catabolic process(GO:0006711)
1.8 5.4 GO:0097037 heme export(GO:0097037)
1.4 14.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.3 3.8 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
1.3 2.5 GO:0018879 biphenyl metabolic process(GO:0018879)
1.2 5.9 GO:0034371 chylomicron remodeling(GO:0034371)
1.1 3.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.0 4.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
1.0 26.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.0 9.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.0 4.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.9 2.6 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.8 2.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.8 3.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.7 2.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.7 2.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.7 44.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.7 4.9 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.6 1.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426) positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.6 1.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.6 2.9 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.5 8.9 GO:0006968 cellular defense response(GO:0006968)
0.5 8.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.5 3.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 1.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 4.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.3 GO:0060032 floor plate formation(GO:0021508) notochord regression(GO:0060032)
0.4 3.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4 1.2 GO:0036269 swimming behavior(GO:0036269)
0.4 3.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 1.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.4 1.5 GO:1903943 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.4 3.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 3.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.4 1.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.3 1.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 3.7 GO:0061042 vascular wound healing(GO:0061042)
0.3 2.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 4.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 2.0 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.3 4.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 2.0 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.6 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 2.7 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 4.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 2.9 GO:0070842 aggresome assembly(GO:0070842)
0.2 4.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 1.2 GO:0019371 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.2 1.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.8 GO:0035566 regulation of metanephros size(GO:0035566)
0.2 2.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 6.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.5 GO:0016131 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.2 4.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.9 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 1.0 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.2 0.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 0.5 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.2 5.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.9 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.4 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 13.7 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 3.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.7 GO:0007028 cytoplasm organization(GO:0007028)
0.1 1.0 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 6.2 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.7 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 1.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.1 0.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 1.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 1.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 3.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.8 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 1.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.6 GO:0051923 sulfation(GO:0051923)
0.1 1.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 14.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.3 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 4.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.9 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 10.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 6.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.8 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.2 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.7 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 5.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.6 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.7 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.6 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 1.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 1.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 4.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:1904171 negative regulation of bleb assembly(GO:1904171)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 9.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.7 GO:0097186 amelogenesis(GO:0097186)
0.0 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.7 GO:0042711 maternal behavior(GO:0042711)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 3.3 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.4 GO:2000269 fibroblast apoptotic process(GO:0044346) regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.1 GO:0007032 endosome organization(GO:0007032)
0.0 2.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.6 GO:0046785 microtubule polymerization(GO:0046785)
0.0 1.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 12.6 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 1.3 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.3 GO:0019724 B cell mediated immunity(GO:0019724)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 32.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.0 2.9 GO:0005588 collagen type V trimer(GO:0005588)
0.7 4.9 GO:0005638 lamin filament(GO:0005638)
0.7 4.0 GO:0031262 Ndc80 complex(GO:0031262)
0.6 12.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.5 4.9 GO:0005577 fibrinogen complex(GO:0005577)
0.5 22.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 13.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 11.3 GO:0097386 glial cell projection(GO:0097386)
0.3 1.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 3.0 GO:0036156 inner dynein arm(GO:0036156)
0.2 2.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.3 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 4.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 40.0 GO:0072562 blood microparticle(GO:0072562)
0.1 5.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.5 GO:0070852 cell body fiber(GO:0070852)
0.1 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0097422 tubular endosome(GO:0097422)
0.1 1.6 GO:0097427 microtubule bundle(GO:0097427)
0.1 4.9 GO:0005921 gap junction(GO:0005921)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 1.3 GO:0097542 ciliary tip(GO:0097542)
0.1 2.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 4.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 7.5 GO:0005581 collagen trimer(GO:0005581)
0.1 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.9 GO:0005771 multivesicular body(GO:0005771)
0.1 2.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.0 GO:0042588 zymogen granule(GO:0042588)
0.1 2.9 GO:0016235 aggresome(GO:0016235)
0.1 1.2 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 12.4 GO:0043296 apical junction complex(GO:0043296)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 2.3 GO:0099738 cell cortex region(GO:0099738)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 2.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.2 GO:0005902 microvillus(GO:0005902)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 6.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 39.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 13.8 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.6 GO:0035375 zymogen binding(GO:0035375)
3.8 11.3 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
2.5 15.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
2.1 44.1 GO:0070513 death domain binding(GO:0070513)
2.0 24.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.0 13.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.6 18.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.5 4.5 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.4 4.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
1.3 21.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.2 8.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
1.2 5.9 GO:0035478 chylomicron binding(GO:0035478)
0.9 7.6 GO:0005534 galactose binding(GO:0005534)
0.9 4.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.9 3.5 GO:0019862 IgA binding(GO:0019862)
0.8 3.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 3.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.7 29.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 5.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 2.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 16.6 GO:0001848 complement binding(GO:0001848)
0.5 1.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.5 1.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 12.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 1.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.4 1.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.4 2.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 7.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 2.9 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 4.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 1.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 2.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.5 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 2.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 7.4 GO:0042056 chemoattractant activity(GO:0042056)
0.2 2.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 1.6 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.8 GO:1902271 D3 vitamins binding(GO:1902271)
0.2 3.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.5 GO:0047598 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.2 6.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 4.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 4.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.8 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 6.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.0 GO:0034452 dynactin binding(GO:0034452)
0.1 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 5.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.2 GO:0005537 mannose binding(GO:0005537)
0.1 1.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 3.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.2 GO:0070628 proteasome binding(GO:0070628)
0.1 10.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.1 3.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 10.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 12.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.9 GO:0008009 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.0 12.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 2.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 11.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 5.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 3.2 GO:0003823 antigen binding(GO:0003823)
0.0 1.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 17.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 24.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 11.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 27.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 26.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 3.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 4.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 5.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 2.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 4.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.8 6.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.7 16.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 18.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.6 8.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 4.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 5.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 5.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 3.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 7.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 4.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 5.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 10.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 1.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.6 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 1.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 4.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements