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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxc13_Hoxd13

Z-value: 0.96

Motif logo

Transcription factors associated with Hoxc13_Hoxd13

Gene Symbol Gene ID Gene Info
ENSMUSG00000001655.7 Hoxc13
ENSMUSG00000001819.5 Hoxd13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc13mm39_v1_chr15_+_102829538_1028295680.191.0e-01Click!
Hoxd13mm39_v1_chr2_+_74498551_744986540.104.2e-01Click!

Activity profile of Hoxc13_Hoxd13 motif

Sorted Z-values of Hoxc13_Hoxd13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc13_Hoxd13

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_45542442 8.78 ENSMUST00000086430.5
collagen, type V, alpha 2
chr9_+_92424276 7.06 ENSMUST00000070522.14
ENSMUST00000160359.2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
chr4_+_134042423 6.18 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr15_-_101759212 5.88 ENSMUST00000023790.5
keratin 1
chr6_-_52194440 5.74 ENSMUST00000048715.9
homeobox A7
chr4_-_133329479 5.60 ENSMUST00000057311.4
stratifin
chr17_+_75485906 5.16 ENSMUST00000112514.2
latent transforming growth factor beta binding protein 1
chr16_+_34815177 5.04 ENSMUST00000231589.2
myosin, light polypeptide kinase
chr6_+_24528143 4.82 ENSMUST00000031696.10
ankyrin repeat and SOCS box-containing 15
chr11_+_96177449 4.77 ENSMUST00000049352.8
homeobox B7
chr17_+_75485791 4.65 ENSMUST00000135447.8
ENSMUST00000112516.8
latent transforming growth factor beta binding protein 1
chr6_-_52195663 4.19 ENSMUST00000134367.4
homeobox A7
chr3_+_79793237 4.16 ENSMUST00000029567.9
golgi associated kinase 1B
chr11_+_96214078 4.00 ENSMUST00000093944.10
homeobox B3
chr2_+_74528071 3.98 ENSMUST00000059272.10
homeobox D9
chr14_+_65903840 3.97 ENSMUST00000022610.15
scavenger receptor class A, member 5
chr8_+_15107646 3.94 ENSMUST00000033842.4
myomesin 2
chr10_+_70040483 3.74 ENSMUST00000020090.8
myoregulin
chr7_-_30312246 3.69 ENSMUST00000006476.6
uroplakin 1A
chr10_+_56253418 3.45 ENSMUST00000068581.9
ENSMUST00000217789.2
gap junction protein, alpha 1
chr10_+_28544356 3.37 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
thymocyte selection associated
chr5_+_17779273 2.91 ENSMUST00000030568.14
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_17465410 2.89 ENSMUST00000145492.2
nebulette
chr17_-_31363245 2.86 ENSMUST00000024826.8
trefoil factor 2 (spasmolytic protein 1)
chr12_+_75355082 2.64 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr6_-_52194414 2.54 ENSMUST00000140316.2
homeobox A7
chr10_+_70040504 2.48 ENSMUST00000190199.2
myoregulin
chr14_+_65903878 2.46 ENSMUST00000069226.7
scavenger receptor class A, member 5
chr4_-_141553306 2.42 ENSMUST00000102481.4
chymotrypsin-like elastase family, member 2A
chr15_-_101833160 2.41 ENSMUST00000023797.8
keratin 4
chr1_-_74163575 2.39 ENSMUST00000169786.8
ENSMUST00000212888.2
ENSMUST00000191104.7
tensin 1
chr5_-_122639840 2.28 ENSMUST00000177974.8
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr5_+_114284585 2.25 ENSMUST00000102582.8
acetyl-Coenzyme A carboxylase beta
chr11_+_96085118 2.21 ENSMUST00000062709.4
homeobox B13
chr3_+_126391046 2.13 ENSMUST00000106401.8
calcium/calmodulin-dependent protein kinase II, delta
chr7_+_28240262 2.01 ENSMUST00000119180.4
syncollin
chr4_-_148584906 2.01 ENSMUST00000030840.4
angiopoietin-like 7
chr1_-_156766351 1.99 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr5_+_128677863 1.93 ENSMUST00000117102.4
frizzled class receptor 10
chr1_-_39844467 1.90 ENSMUST00000171319.4
predicted gene 3646
chr3_+_126390951 1.88 ENSMUST00000171289.8
calcium/calmodulin-dependent protein kinase II, delta
chr15_-_101441254 1.85 ENSMUST00000023720.8
keratin 84
chr2_+_35022178 1.75 ENSMUST00000113034.8
ENSMUST00000113037.10
ENSMUST00000150807.6
ENSMUST00000113033.6
centriolin
chr11_-_43492367 1.64 ENSMUST00000020672.5
fatty acid binding protein 6
chr17_-_52133594 1.63 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr1_+_60948149 1.56 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr1_+_107289659 1.55 ENSMUST00000027566.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr15_-_101482320 1.55 ENSMUST00000042957.6
keratin 75
chr9_+_32607301 1.46 ENSMUST00000034534.13
ENSMUST00000050797.14
ENSMUST00000184887.2
E26 avian leukemia oncogene 1, 5' domain
chr2_+_138120401 1.43 ENSMUST00000075410.5
BTB (POZ) domain containing 3
chr13_-_19917092 1.39 ENSMUST00000151029.3
G protein-coupled receptor 141B
chr1_+_72346572 1.32 ENSMUST00000027379.10
X-ray repair complementing defective repair in Chinese hamster cells 5
chr11_-_99996452 1.30 ENSMUST00000107416.3
keratin 36
chr19_-_7319157 1.30 ENSMUST00000164205.8
ENSMUST00000165286.8
ENSMUST00000168324.2
ENSMUST00000032557.15
MAP/microtubule affinity regulating kinase 2
chr6_+_83063348 1.30 ENSMUST00000041265.4
ladybird homeobox 2
chr14_-_103584179 1.29 ENSMUST00000159855.8
MYC binding protein 2, E3 ubiquitin protein ligase
chr8_-_70591746 1.25 ENSMUST00000212320.2
regulatory factor X-associated ankyrin-containing protein
chr9_-_77255069 1.16 ENSMUST00000184848.8
ENSMUST00000184415.8
muscular LMNA-interacting protein
chr6_-_24528012 1.14 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr9_-_77255099 1.12 ENSMUST00000184138.8
ENSMUST00000184006.8
ENSMUST00000185144.8
ENSMUST00000034910.16
muscular LMNA-interacting protein
chr10_+_28544556 1.09 ENSMUST00000161345.2
thymocyte selection associated
chr15_+_78867241 1.08 ENSMUST00000109687.9
ENSMUST00000130663.10
TRIO and F-actin binding protein
chrX_+_162923474 1.03 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr1_-_156766381 1.03 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_171854818 1.02 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr17_+_46961250 1.01 ENSMUST00000043464.14
cullin 7
chrX_+_95498965 0.98 ENSMUST00000033553.14
hephaestin
chr2_-_73316053 0.96 ENSMUST00000102680.8
WAS/WASL interacting protein family, member 1
chr13_-_40887444 0.93 ENSMUST00000224665.2
transcription factor AP-2, alpha
chr5_+_92957231 0.92 ENSMUST00000113054.9
shroom family member 3
chr10_+_56253531 0.92 ENSMUST00000220194.2
ENSMUST00000218834.2
gap junction protein, alpha 1
chr4_-_136329953 0.92 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr15_+_98972850 0.89 ENSMUST00000039665.8
trophinin associated protein
chr4_-_63090355 0.86 ENSMUST00000156618.9
ENSMUST00000030042.3
kinesin family member 12
chr11_-_88608958 0.86 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr5_-_86893645 0.85 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr7_-_102408573 0.83 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
olfactory receptor 560
olfactory receptor 78
chr6_+_71886030 0.83 ENSMUST00000055296.11
polymerase (RNA) I polypeptide A
chr15_-_101459092 0.81 ENSMUST00000023713.10
keratin 82
chr9_+_5308828 0.79 ENSMUST00000162846.8
ENSMUST00000027012.14
caspase 4, apoptosis-related cysteine peptidase
chr3_-_88317601 0.78 ENSMUST00000193338.6
ENSMUST00000056370.13
polyamine-modulated factor 1
chr14_+_32043944 0.77 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr9_+_110948492 0.73 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr11_+_77107006 0.70 ENSMUST00000156488.8
ENSMUST00000037912.12
slingshot protein phosphatase 2
chr10_-_35587888 0.65 ENSMUST00000080898.4
S-adenosylmethionine decarboxylase 2
chr15_+_6552270 0.64 ENSMUST00000226412.2
FYN binding protein
chr9_-_77255171 0.63 ENSMUST00000185039.8
muscular LMNA-interacting protein
chr15_-_101336669 0.60 ENSMUST00000081945.5
keratin 87
chr9_-_50571080 0.60 ENSMUST00000034567.4
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr1_+_60948307 0.58 ENSMUST00000097720.4
cytotoxic T-lymphocyte-associated protein 4
chr7_+_67297152 0.57 ENSMUST00000032774.16
ENSMUST00000107471.8
tetratricopeptide repeat domain 23
chr15_-_78947038 0.56 ENSMUST00000151889.8
ENSMUST00000040676.11
ankyrin repeat domain 54
chr10_+_127851031 0.55 ENSMUST00000178041.8
ENSMUST00000026461.8
DNA primase, p49 subunit
chr4_-_82768958 0.54 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chr1_+_85538554 0.52 ENSMUST00000162925.2
Sp140 nuclear body protein
chr11_-_100510992 0.49 ENSMUST00000014339.15
ENSMUST00000239490.2
ENSMUST00000239410.2
DnaJ heat shock protein family (Hsp40) member C7
chr2_+_112096154 0.47 ENSMUST00000110991.9
solute carrier family 12, member 6
chr3_-_49711706 0.47 ENSMUST00000191794.2
protocadherin 18
chr11_-_99877423 0.47 ENSMUST00000105050.4
keratin associated protein 16-1
chr17_+_37274714 0.44 ENSMUST00000209623.2
RNA polymerase I subunit H, antisense
chr10_-_107321938 0.43 ENSMUST00000000445.2
myogenic factor 5
chr1_+_53352780 0.43 ENSMUST00000027265.10
ENSMUST00000114484.8
O-sialoglycoprotein endopeptidase-like 1
chr17_-_36149100 0.41 ENSMUST00000134978.3
tubulin, beta 5 class I
chr13_+_35843816 0.40 ENSMUST00000075220.14
chromodomain protein, Y chromosome-like
chr2_-_127634387 0.40 ENSMUST00000135091.2
mitoregulin
chr8_-_70591799 0.39 ENSMUST00000075724.9
regulatory factor X-associated ankyrin-containing protein
chrX_-_7185424 0.38 ENSMUST00000115746.8
chloride channel, voltage-sensitive 5
chr19_-_7319211 0.38 ENSMUST00000171393.8
MAP/microtubule affinity regulating kinase 2
chr18_-_46413886 0.36 ENSMUST00000236999.2
protein geranylgeranyltransferase type I, beta subunit
chr13_-_21586858 0.32 ENSMUST00000117721.8
ENSMUST00000070785.16
ENSMUST00000116433.2
ENSMUST00000223831.2
ENSMUST00000116434.11
ENSMUST00000224820.2
zinc finger with KRAB and SCAN domains 3
chr8_-_25528972 0.32 ENSMUST00000084031.6
HtrA serine peptidase 4
chrX_-_7185529 0.31 ENSMUST00000128319.2
chloride channel, voltage-sensitive 5
chr17_+_35658131 0.31 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
histocompatibility 2, Q region locus 7
chr10_-_8394546 0.30 ENSMUST00000061601.9
uronyl-2-sulfotransferase
chr9_-_63929308 0.28 ENSMUST00000179458.2
ENSMUST00000041029.6
SMAD family member 6
chr1_-_156766957 0.28 ENSMUST00000171292.8
ENSMUST00000063199.13
ENSMUST00000027886.14
Ral GEF with PH domain and SH3 binding motif 2
chr11_+_60066681 0.27 ENSMUST00000102688.2
retinoic acid induced 1
chr7_-_28330322 0.27 ENSMUST00000040112.5
ENSMUST00000239470.2
acid phosphatase 7, tartrate resistant
chr4_+_21879660 0.26 ENSMUST00000029909.3
coenzyme Q3 methyltransferase
chr15_+_66542598 0.23 ENSMUST00000065916.14
thyroglobulin
chr1_+_83022653 0.23 ENSMUST00000222567.2
predicted gene, 47969
chr3_+_88528410 0.22 ENSMUST00000029694.14
ENSMUST00000176804.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chrX_+_41241049 0.22 ENSMUST00000128799.3
stromal antigen 2
chr8_+_96058907 0.22 ENSMUST00000034245.16
U6 snRNA biogenesis 1
chr18_+_44249254 0.17 ENSMUST00000212114.2
predicted gene, 37797
chr2_+_20727274 0.15 ENSMUST00000114607.8
enhancer trap locus 4
chr7_-_28329924 0.15 ENSMUST00000159095.2
ENSMUST00000159418.8
ENSMUST00000159560.3
acid phosphatase 7, tartrate resistant
chr18_+_69478893 0.15 ENSMUST00000202354.4
transcription factor 4
chr8_+_105991280 0.14 ENSMUST00000036221.12
F-box and leucine-rich repeat protein 8
chr11_-_23845207 0.11 ENSMUST00000102863.3
ENSMUST00000020513.10
poly(A) polymerase gamma
chr17_-_36149142 0.11 ENSMUST00000001566.10
tubulin, beta 5 class I
chr3_+_102642516 0.10 ENSMUST00000119902.6
tetraspanin 2
chr15_-_79658608 0.10 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr9_-_96601574 0.10 ENSMUST00000128269.8
zinc finger and BTB domain containing 38
chr15_-_79658584 0.09 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr9_+_38119661 0.09 ENSMUST00000211975.3
olfactory receptor 893
chr3_-_75359125 0.08 ENSMUST00000204341.3
WD repeat domain 49
chrX_+_7750558 0.08 ENSMUST00000208640.2
ENSMUST00000207114.2
ENSMUST00000208633.2
ENSMUST00000208397.2
ENSMUST00000153620.3
ENSMUST00000123277.8
solute carrier family 35 (UDP-galactose transporter), member A2
chr4_-_44710408 0.07 ENSMUST00000134968.9
ENSMUST00000173821.8
ENSMUST00000174319.8
ENSMUST00000173733.8
ENSMUST00000172866.8
ENSMUST00000165417.9
ENSMUST00000107825.9
ENSMUST00000102932.10
ENSMUST00000107827.9
ENSMUST00000107826.9
ENSMUST00000014174.14
paired box 5
chr11_-_99433984 0.07 ENSMUST00000107443.8
ENSMUST00000074253.4
keratin 40
chr18_+_36877709 0.04 ENSMUST00000007042.6
ENSMUST00000237095.2
IK cytokine
chr8_-_37200051 0.02 ENSMUST00000098826.10
deleted in liver cancer 1
chr7_-_130748035 0.02 ENSMUST00000070980.4
RIKEN cDNA 4933402N03 gene
chr9_-_110775143 0.01 ENSMUST00000199782.2
ENSMUST00000035075.13
teratocarcinoma-derived growth factor 1
chr5_+_86952072 0.01 ENSMUST00000119339.8
ENSMUST00000120498.8
YTH domain containing 1
chr18_-_84854841 0.00 ENSMUST00000236689.2
predicted gene, 17266
chr5_+_150119860 0.00 ENSMUST00000202600.4
FRY microtubule binding protein
chr16_-_57051727 0.00 ENSMUST00000226586.2
TBC1 domain family, member 23

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
2.1 6.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.9 5.6 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
1.6 6.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.5 4.4 GO:0060156 vascular transport(GO:0010232) milk ejection(GO:0060156)
1.4 7.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.1 2.3 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
1.0 12.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
1.0 5.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.8 2.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.7 4.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.7 4.0 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.6 2.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.5 1.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.5 5.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 2.9 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.4 2.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.4 2.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.3 1.3 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.3 3.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.3 0.8 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.3 9.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 1.0 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 3.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.9 GO:0046098 guanine metabolic process(GO:0046098)
0.2 0.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.9 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 4.5 GO:0043383 negative T cell selection(GO:0043383)
0.2 4.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 6.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 2.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.9 GO:0003409 optic cup structural organization(GO:0003409)
0.2 4.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.7 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.5 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 1.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 3.2 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 2.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 2.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.6 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 2.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.1 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.8 GO:0035904 aorta development(GO:0035904)
0.0 1.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 1.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 1.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
2.9 8.8 GO:0005588 collagen type V trimer(GO:0005588)
0.8 2.3 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.3 13.6 GO:0045095 keratin filament(GO:0045095)
0.2 1.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 6.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 4.4 GO:0005916 fascia adherens(GO:0005916)
0.2 0.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 1.0 GO:1990393 3M complex(GO:1990393)
0.2 0.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 3.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.7 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 4.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0045298 tubulin complex(GO:0045298)
0.0 2.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 4.0 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 4.5 GO:0016605 PML body(GO:0016605)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 5.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.9 GO:0043292 contractile fiber(GO:0043292)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 9.8 GO:0050436 microfibril binding(GO:0050436)
1.5 9.0 GO:0030280 structural constituent of epidermis(GO:0030280)
1.4 7.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.3 6.4 GO:0070287 ferritin receptor activity(GO:0070287)
0.7 10.2 GO:0031432 titin binding(GO:0031432)
0.6 4.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.6 5.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 2.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 2.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 3.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 0.6 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 8.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.6 GO:0032052 bile acid binding(GO:0032052)
0.1 1.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.7 GO:0019808 polyamine binding(GO:0019808)
0.1 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 17.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 4.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0046977 TAP binding(GO:0046977)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 7.5 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 6.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 7.9 GO:0003779 actin binding(GO:0003779)
0.0 5.6 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.0 PID AURORA B PATHWAY Aurora B signaling
0.1 4.0 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 9.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 5.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 10.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 5.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 11.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling