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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxd11_Cdx1_Hoxc11

Z-value: 1.70

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Transcription factors associated with Hoxd11_Cdx1_Hoxc11

Gene Symbol Gene ID Gene Info
ENSMUSG00000042499.14 Hoxd11
ENSMUSG00000024619.9 Cdx1
ENSMUSG00000001656.4 Hoxc11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdx1mm39_v1_chr18_-_61169262_611692820.748.1e-14Click!
Hoxd11mm39_v1_chr2_+_74512638_745126700.431.6e-04Click!
Hoxc11mm39_v1_chr15_+_102862862_1028629310.103.9e-01Click!

Activity profile of Hoxd11_Cdx1_Hoxc11 motif

Sorted Z-values of Hoxd11_Cdx1_Hoxc11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd11_Cdx1_Hoxc11

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_71176811 30.18 ENSMUST00000067492.8
fatty acid binding protein 1, liver
chr7_-_135130374 24.68 ENSMUST00000053716.8
clarin 3
chr3_+_3699205 23.35 ENSMUST00000108394.3
hepatocyte nuclear factor 4, gamma
chr4_+_11758147 22.90 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chrX_+_95498965 20.47 ENSMUST00000033553.14
hephaestin
chr11_-_100036792 17.57 ENSMUST00000007317.8
keratin 19
chr7_+_123061497 16.71 ENSMUST00000033023.10
aquaporin 8
chr13_-_24098981 16.66 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr7_+_123061535 16.61 ENSMUST00000098056.6
aquaporin 8
chr17_+_31652073 16.46 ENSMUST00000237363.2
phosphodiesterase 9A
chr17_+_31652029 16.42 ENSMUST00000136384.9
phosphodiesterase 9A
chr16_-_56616186 15.86 ENSMUST00000023437.5
adhesion G protein-coupled receptor G7
chr7_-_140856642 15.82 ENSMUST00000080654.7
ENSMUST00000167263.9
cadherin-related family member 5
chr13_-_24098951 15.79 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr14_-_36832044 14.20 ENSMUST00000179488.3
RIKEN cDNA 2610528A11 gene
chr10_-_116732813 13.35 ENSMUST00000048229.9
myelin regulatory factor-like
chr10_+_116013256 13.34 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr3_-_144638284 12.25 ENSMUST00000098549.4
chloride channel accessory 4B
chr2_+_57887896 11.55 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr2_+_163348728 11.08 ENSMUST00000143911.8
hepatic nuclear factor 4, alpha
chr1_+_165958036 10.69 ENSMUST00000166860.2
glycoprotein A33 (transmembrane)
chr10_+_116013122 10.67 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr8_-_5155347 9.97 ENSMUST00000023835.3
solute carrier family 10, member 2
chr3_-_72875187 9.20 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr17_-_43813664 9.03 ENSMUST00000024707.9
ENSMUST00000117137.8
meprin 1 alpha
chr6_-_24168082 8.81 ENSMUST00000031713.9
solute carrier family 13 (sodium/sulfate symporters), member 1
chr19_-_10995390 8.59 ENSMUST00000177684.3
membrane-spanning 4-domains, subfamily A, member 18
chr11_+_96085118 7.77 ENSMUST00000062709.4
homeobox B13
chr7_+_130633776 7.59 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chrX_+_138464065 7.35 ENSMUST00000113027.8
ring finger protein 128
chr6_-_52203146 7.25 ENSMUST00000114425.3
homeobox A9
chr15_-_78739717 7.15 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chr3_+_57332735 7.00 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr3_-_144555062 6.92 ENSMUST00000159989.2
chloride channel accessory 3B
chr19_+_24853039 6.89 ENSMUST00000073080.7
predicted gene 10053
chr18_+_21205386 6.88 ENSMUST00000082235.5
meprin 1 beta
chr2_-_103114105 6.58 ENSMUST00000111174.8
ets homologous factor
chr18_-_32170012 6.43 ENSMUST00000134663.2
myosin VIIB
chr1_+_165957784 6.41 ENSMUST00000060833.14
glycoprotein A33 (transmembrane)
chr7_+_141276575 6.40 ENSMUST00000185406.8
mucin 2
chr11_-_43492367 6.09 ENSMUST00000020672.5
fatty acid binding protein 6
chr3_-_63758672 6.05 ENSMUST00000162269.9
ENSMUST00000159676.9
ENSMUST00000175947.8
phospholipase C, eta 1
chr19_+_56414114 5.56 ENSMUST00000238892.2
caspase 7
chr10_+_79656823 5.49 ENSMUST00000169041.9
mitotic spindle positioning
chrX_+_162923474 5.47 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr3_+_138019040 5.40 ENSMUST00000013455.13
ENSMUST00000106247.2
alcohol dehydrogenase 6A (class V)
chr16_-_21814190 5.08 ENSMUST00000231766.2
ENSMUST00000074230.12
lipase, member H
chr1_+_165957909 4.75 ENSMUST00000166159.2
glycoprotein A33 (transmembrane)
chr2_+_122129379 4.62 ENSMUST00000028656.2
dual oxidase maturation factor 2
chr6_-_83513222 4.59 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr6_-_52195663 4.54 ENSMUST00000134367.4
homeobox A7
chr1_-_45542442 4.49 ENSMUST00000086430.5
collagen, type V, alpha 2
chr6_-_83513184 4.33 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr1_+_74752710 4.32 ENSMUST00000027356.7
cytochrome P450, family 27, subfamily a, polypeptide 1
chr3_+_62327089 4.31 ENSMUST00000161057.2
Rho guanine nucleotide exchange factor (GEF) 26
chr7_-_30312246 4.28 ENSMUST00000006476.6
uroplakin 1A
chr16_-_21814289 4.24 ENSMUST00000060673.8
lipase, member H
chr17_+_3447465 4.20 ENSMUST00000072156.7
T cell lymphoma invasion and metastasis 2
chr9_-_9239056 4.18 ENSMUST00000093893.12
Rho GTPase activating protein 42
chr3_+_138121245 3.91 ENSMUST00000161312.8
ENSMUST00000013458.9
alcohol dehydrogenase 4 (class II), pi polypeptide
chr1_-_128256048 3.88 ENSMUST00000073490.7
lactase
chr13_-_23806530 3.83 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr10_+_5589210 3.83 ENSMUST00000019906.6
vasoactive intestinal polypeptide
chr5_+_63969706 3.78 ENSMUST00000081747.8
ENSMUST00000196575.5
RIKEN cDNA 0610040J01 gene
chr2_-_160208977 3.68 ENSMUST00000099126.5
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr6_-_52211882 3.62 ENSMUST00000125581.2
homeobox A10
chr2_+_15531281 3.41 ENSMUST00000146205.3
MAM and LDL receptor class A domain containing 1
chr1_-_57008986 3.38 ENSMUST00000176759.2
ENSMUST00000177424.2
special AT-rich sequence binding protein 2
chr7_-_19411866 3.20 ENSMUST00000142352.9
apolipoprotein C-II
chr1_-_37535170 3.11 ENSMUST00000148047.2
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_-_37535202 3.07 ENSMUST00000143636.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr5_-_87485023 3.05 ENSMUST00000031195.3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_177557380 3.05 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr6_-_70412460 3.02 ENSMUST00000103394.2
immunoglobulin kappa variable 6-14
chr10_-_40018243 2.99 ENSMUST00000092566.8
ENSMUST00000213488.2
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr6_-_119365632 2.98 ENSMUST00000169744.8
adiponectin receptor 2
chr5_-_120610828 2.97 ENSMUST00000052258.14
ENSMUST00000031594.13
serine dehydratase-like
chr14_+_31807760 2.97 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
oxidoreductase NAD-binding domain containing 1
chr10_+_101517348 2.94 ENSMUST00000179929.8
ENSMUST00000219195.2
ENSMUST00000127504.9
MGAT4 family, member C
chr3_-_88366351 2.57 ENSMUST00000165898.8
ENSMUST00000127436.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr5_-_73349191 2.56 ENSMUST00000176910.3
FRY like transcription coactivator
chrX_-_133442596 2.54 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr3_-_144525255 2.53 ENSMUST00000029929.12
chloride channel accessory 3A2
chr9_+_103917821 2.49 ENSMUST00000216593.2
ENSMUST00000147249.3
nephronophthisis 3 (adolescent)
predicted gene 28305
chr8_+_110717062 2.46 ENSMUST00000001720.14
ENSMUST00000143741.2
tyrosine aminotransferase
chr15_-_101336669 2.44 ENSMUST00000081945.5
keratin 87
chr6_-_70435020 2.44 ENSMUST00000198184.2
immunoglobulin kappa variable 6-13
chr1_-_71692320 2.41 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr4_-_102883905 2.40 ENSMUST00000084382.6
ENSMUST00000106869.3
insulin-like 5
chr3_-_49711706 2.37 ENSMUST00000191794.2
protocadherin 18
chrX_+_55824797 2.37 ENSMUST00000114773.10
four and a half LIM domains 1
chr19_+_58748132 2.29 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr9_+_110948492 2.23 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr17_-_35293447 2.21 ENSMUST00000007259.4
lymphocyte antigen 6 complex, locus G6D
chr5_-_51725059 2.16 ENSMUST00000127135.3
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr17_+_71326510 2.16 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr8_+_57774010 2.11 ENSMUST00000040104.5
heart and neural crest derivatives expressed 2
chr10_-_128996851 2.04 ENSMUST00000078914.3
olfactory receptor 771
chr7_+_126808016 2.04 ENSMUST00000206204.2
ENSMUST00000206772.2
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_-_36207965 1.98 ENSMUST00000150056.2
ENSMUST00000156817.2
ENSMUST00000146451.8
ENSMUST00000148482.8
RIKEN cDNA 2310061I04 gene
chr17_+_71326542 1.97 ENSMUST00000179759.3
myomesin 1
chr1_-_37575313 1.97 ENSMUST00000042161.15
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr9_+_111014254 1.92 ENSMUST00000198986.2
leucine rich repeat (in FLII) interacting protein 2
chr1_+_45350698 1.90 ENSMUST00000087883.13
collagen, type III, alpha 1
chr10_-_107321938 1.89 ENSMUST00000000445.2
myogenic factor 5
chr3_-_49711765 1.86 ENSMUST00000035931.13
protocadherin 18
chr10_+_26698556 1.82 ENSMUST00000135866.2
Rho GTPase activating protein 18
chr1_-_144052997 1.81 ENSMUST00000111941.2
ENSMUST00000052375.8
regulator of G-protein signaling 13
chr1_-_144124871 1.79 ENSMUST00000189061.7
regulator of G-protein signaling 1
chrX_+_132809189 1.76 ENSMUST00000113304.2
sushi-repeat-containing protein, X-linked 2
chr10_-_25076008 1.71 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr2_-_136727599 1.70 ENSMUST00000231720.2
novel protein
chr17_-_16046780 1.64 ENSMUST00000232638.2
ENSMUST00000170578.3
repulsive guidance molecule family member B
chr6_-_124942457 1.63 ENSMUST00000112439.9
COP9 signalosome subunit 7A
chr6_-_124942366 1.63 ENSMUST00000129446.8
ENSMUST00000032220.15
COP9 signalosome subunit 7A
chr4_+_116578117 1.62 ENSMUST00000045542.13
ENSMUST00000106459.8
testis-specific kinase 2
chr15_+_25774070 1.62 ENSMUST00000125667.3
myosin X
chr3_-_19319123 1.59 ENSMUST00000121951.2
phosphodiesterase 7A
chr7_-_44711771 1.57 ENSMUST00000210101.2
ENSMUST00000209219.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr8_-_45747883 1.54 ENSMUST00000026907.6
kallikrein B, plasma 1
chr4_-_76262464 1.50 ENSMUST00000050757.16
protein tyrosine phosphatase, receptor type, D
chr5_+_4073343 1.48 ENSMUST00000238634.2
A kinase (PRKA) anchor protein (yotiao) 9
chr3_-_88366159 1.46 ENSMUST00000147200.8
ENSMUST00000169222.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_70355208 1.45 ENSMUST00000110167.5
NADH:ubiquinone oxidoreductase subunit A13
chr18_+_65054188 1.45 ENSMUST00000236898.2
ENSMUST00000237410.2
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr11_-_21320452 1.45 ENSMUST00000102875.11
UDP-glucose pyrophosphorylase 2
chr15_+_59186876 1.45 ENSMUST00000022977.14
ENSMUST00000100640.5
squalene epoxidase
chr7_-_141015240 1.45 ENSMUST00000138865.8
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr2_+_113235475 1.44 ENSMUST00000238883.2
formin 1
chr5_-_73413888 1.43 ENSMUST00000101127.12
FRY like transcription coactivator
chr8_-_58106057 1.41 ENSMUST00000034021.12
polypeptide N-acetylgalactosaminyltransferase 7
chr2_-_86180622 1.39 ENSMUST00000099894.5
ENSMUST00000213564.3
olfactory receptor 1055
chr9_-_96774719 1.36 ENSMUST00000154146.8
2-phosphoxylose phosphatase 1
chr7_-_44711075 1.34 ENSMUST00000007981.9
ENSMUST00000210500.2
ENSMUST00000210493.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr7_+_140343652 1.32 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr10_-_105410280 1.28 ENSMUST00000061506.9
transmembrane and tetratricopeptide repeat containing 2
chr14_-_31807552 1.23 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
diphthamine biosynthesis 3
chr9_-_44710480 1.20 ENSMUST00000214833.2
ENSMUST00000213972.2
ENSMUST00000214431.2
ENSMUST00000213363.2
ENSMUST00000114705.9
ENSMUST00000002100.8
transmembrane protein 25
chr13_+_13612136 1.17 ENSMUST00000005532.9
nidogen 1
chr7_-_44711130 1.16 ENSMUST00000211337.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr16_-_55659194 1.16 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr2_-_32341408 1.14 ENSMUST00000028160.15
ENSMUST00000113310.9
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr9_+_21746785 1.13 ENSMUST00000058777.8
angiopoietin-like 8
chr14_+_28233301 1.13 ENSMUST00000112272.2
wingless-type MMTV integration site family, member 5A
chr6_-_124942170 1.09 ENSMUST00000148485.2
ENSMUST00000129976.8
COP9 signalosome subunit 7A
chrX_-_7185424 1.09 ENSMUST00000115746.8
chloride channel, voltage-sensitive 5
chr19_-_7943365 1.08 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr3_+_102981352 1.06 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr11_+_97689819 1.04 ENSMUST00000143571.2
LIM and SH3 protein 1
chr4_-_49408040 1.01 ENSMUST00000081541.9
acyl-coenzyme A amino acid N-acyltransferase 2
chr2_-_140513382 0.98 ENSMUST00000110057.3
fibronectin leucine rich transmembrane protein 3
chr4_-_63965161 0.97 ENSMUST00000107377.10
tenascin C
chr12_-_111933328 0.97 ENSMUST00000222874.2
ENSMUST00000223191.2
ENSMUST00000021719.7
ATP synthase membrane subunit 6.8PL
chr5_-_87572060 0.94 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chrX_+_132809166 0.93 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr7_+_127399776 0.91 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_101785181 0.88 ENSMUST00000057054.8
mesenchyme homeobox 1
chr14_-_24053994 0.87 ENSMUST00000225431.2
ENSMUST00000188210.8
ENSMUST00000224787.2
ENSMUST00000225315.2
ENSMUST00000225556.2
ENSMUST00000223727.2
ENSMUST00000223655.2
ENSMUST00000224077.2
ENSMUST00000224812.2
ENSMUST00000224285.2
ENSMUST00000225471.2
ENSMUST00000224232.2
ENSMUST00000223749.2
ENSMUST00000224025.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_140513320 0.87 ENSMUST00000056760.4
fibronectin leucine rich transmembrane protein 3
chr15_-_77129786 0.84 ENSMUST00000228558.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_-_77129706 0.83 ENSMUST00000228361.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_82915031 0.83 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr15_-_34356567 0.82 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr11_-_17161504 0.82 ENSMUST00000020317.8
partner of NOB1 homolog
chr16_+_88812172 0.82 ENSMUST00000089106.4
predicted gene 10229
chr16_+_29884153 0.82 ENSMUST00000023171.8
hes family bHLH transcription factor 1
chr19_-_6117815 0.81 ENSMUST00000162575.8
ENSMUST00000159084.8
ENSMUST00000161718.8
ENSMUST00000162810.8
ENSMUST00000025713.12
ENSMUST00000113543.9
ENSMUST00000160417.8
ENSMUST00000161528.2
transmembrane 7 superfamily member 2
chr13_+_81031512 0.81 ENSMUST00000099356.10
arrestin domain containing 3
chr16_+_41353360 0.81 ENSMUST00000099761.10
limbic system-associated membrane protein
chr19_-_7319211 0.81 ENSMUST00000171393.8
MAP/microtubule affinity regulating kinase 2
chr6_-_139478919 0.79 ENSMUST00000170650.3
RERG/RAS-like
chr2_-_26012751 0.77 ENSMUST00000140993.2
ENSMUST00000028300.6
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chrX_-_7185529 0.76 ENSMUST00000128319.2
chloride channel, voltage-sensitive 5
chr7_-_141014477 0.75 ENSMUST00000106007.10
ENSMUST00000150026.2
ENSMUST00000202840.4
ENSMUST00000133206.9
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr4_+_118217179 0.74 ENSMUST00000006562.6
hydroxypyruvate isomerase (putative)
chr19_+_44481901 0.72 ENSMUST00000041163.5
wingless-type MMTV integration site family, member 8B
chr17_-_36208265 0.71 ENSMUST00000148721.8
RIKEN cDNA 2310061I04 gene
chr2_+_29678248 0.69 ENSMUST00000028137.10
ENSMUST00000148791.2
coenzyme Q4
chr17_+_8502682 0.69 ENSMUST00000124023.8
mitochondrial pyruvate carrier 1
chr12_+_55349422 0.69 ENSMUST00000021411.15
protein only RNase P catalytic subunit
chr10_-_30494333 0.68 ENSMUST00000019925.7
histidine triad nucleotide binding protein 3
chr15_-_41733099 0.67 ENSMUST00000054742.7
actin-binding Rho activating protein
chr18_-_47466378 0.67 ENSMUST00000126684.2
ENSMUST00000156422.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr13_+_46427176 0.67 ENSMUST00000076622.4
stathmin domain containing 1
chr10_-_53952686 0.67 ENSMUST00000220088.2
mannosidase 1, alpha
chr10_+_23814470 0.67 ENSMUST00000079134.5
trace amine-associated receptor 2
chr13_+_22220000 0.65 ENSMUST00000110455.4
H2B clustered histone 12
chr16_-_58459102 0.64 ENSMUST00000053249.9
ferritin domain containing 2
chr14_-_7750938 0.63 ENSMUST00000223740.3
ENSMUST00000224049.3
ENSMUST00000224672.3
ENSMUST00000224752.3
ENSMUST00000223695.3
ENSMUST00000224333.3
ENSMUST00000224952.3
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr15_-_101422054 0.63 ENSMUST00000230067.3
predicted gene, 49425
chr2_+_74552322 0.63 ENSMUST00000047904.4
homeobox D4
chrX_+_81992467 0.63 ENSMUST00000114000.8
dystrophin, muscular dystrophy
chr19_-_45224251 0.63 ENSMUST00000099401.6
ladybird homeobox 1
chr13_-_3995349 0.61 ENSMUST00000058610.8
urocortin 3
chr3_+_122298308 0.60 ENSMUST00000199358.2
breast cancer anti-estrogen resistance 3
chr9_-_101076198 0.58 ENSMUST00000066773.9
protein phosphatase 2, regulatory subunit B'', alpha
chr16_-_35589726 0.58 ENSMUST00000023554.9
solute carrier family 49 member 4
chr3_+_89366425 0.56 ENSMUST00000029564.12
phosphomevalonate kinase
chr2_+_145627900 0.55 ENSMUST00000110005.8
ENSMUST00000094480.11
Ras and Rab interactor 2
chr1_-_144124787 0.55 ENSMUST00000185714.2
regulator of G-protein signaling 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
4.4 22.2 GO:1904970 brush border assembly(GO:1904970)
4.2 33.3 GO:0015722 canalicular bile acid transport(GO:0015722)
4.0 24.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
3.7 11.1 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
1.9 7.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
1.9 30.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
1.5 32.9 GO:0046069 cGMP catabolic process(GO:0046069)
1.4 5.5 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.1 4.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.1 5.6 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.0 3.9 GO:0006069 ethanol oxidation(GO:0006069)
0.8 4.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.8 4.1 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.8 2.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.8 3.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.7 3.7 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7 3.7 GO:0010040 response to iron(II) ion(GO:0010040)
0.7 2.2 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.6 1.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 4.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.6 3.4 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.5 19.8 GO:0006825 copper ion transport(GO:0006825)
0.5 1.5 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.4 2.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 0.8 GO:2000974 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.4 8.8 GO:0008272 sulfate transport(GO:0008272)
0.4 1.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4 10.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 1.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.4 6.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 1.1 GO:0061354 chemorepulsion of dopaminergic neuron axon(GO:0036518) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) melanocyte proliferation(GO:0097325) regulation of cell proliferation in midbrain(GO:1904933)
0.4 2.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.4 17.6 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.3 4.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 22.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 10.0 GO:0060065 uterus development(GO:0060065)
0.3 3.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 7.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 2.5 GO:0046689 tyrosine catabolic process(GO:0006572) response to mercury ion(GO:0046689)
0.3 0.5 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3 0.8 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.3 1.8 GO:0003344 pericardium morphogenesis(GO:0003344)
0.3 4.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 0.8 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 3.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 4.3 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.6 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.2 33.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 1.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 2.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 3.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 3.1 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 6.1 GO:0008206 bile acid metabolic process(GO:0008206)
0.2 3.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 2.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 7.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 4.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.9 GO:0001757 somite specification(GO:0001757)
0.1 0.9 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732) striated muscle atrophy(GO:0014891)
0.1 1.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 1.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 2.3 GO:0019374 galactolipid metabolic process(GO:0019374) glycolipid catabolic process(GO:0019377)
0.1 0.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 4.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.1 6.7 GO:1901998 toxin transport(GO:1901998)
0.1 0.6 GO:0021747 cochlear nucleus development(GO:0021747)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 23.2 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 0.9 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.1 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 8.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 2.4 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.1 2.2 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.4 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.0 1.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 1.1 GO:0032094 response to food(GO:0032094)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 5.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 10.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.7 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 1.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.3 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:2001269 interleukin-6-mediated signaling pathway(GO:0070102) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 3.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 33.3 GO:0046691 intracellular canaliculus(GO:0046691)
2.7 30.2 GO:0045179 apical cortex(GO:0045179)
2.0 17.6 GO:1990357 terminal web(GO:1990357)
1.6 15.8 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.5 4.5 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.2 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.6 2.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.6 7.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4 3.2 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.5 GO:0044307 dendritic branch(GO:0044307)
0.3 3.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.3 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.2 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 31.5 GO:0043204 perikaryon(GO:0043204)
0.1 13.8 GO:0005902 microvillus(GO:0005902)
0.1 2.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 39.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 13.1 GO:0005903 brush border(GO:0005903)
0.1 42.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 4.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 5.6 GO:0005770 late endosome(GO:0005770)
0.0 6.7 GO:0072562 blood microparticle(GO:0072562)
0.0 43.4 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.2 GO:0005767 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 118.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.1 GO:0030175 filopodium(GO:0030175)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 7.4 GO:0005925 focal adhesion(GO:0005925)
0.0 3.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 22.9 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
4.3 30.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
3.7 11.1 GO:0070540 stearic acid binding(GO:0070540)
2.5 7.6 GO:0035375 zymogen binding(GO:0035375)
2.3 9.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
2.0 32.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.9 33.3 GO:0015250 water channel activity(GO:0015250)
1.7 20.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.3 3.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.2 10.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.1 32.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
1.0 11.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.0 3.0 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.9 5.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 2.5 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.7 21.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.6 3.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.6 6.1 GO:0032052 bile acid binding(GO:0032052)
0.6 3.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.6 3.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.6 13.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 3.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 4.5 GO:0016936 galactoside binding(GO:0016936)
0.5 8.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4 5.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 1.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.4 24.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 0.8 GO:0071820 N-box binding(GO:0071820)
0.2 2.4 GO:0045340 mercury ion binding(GO:0045340)
0.2 22.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 6.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.9 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.2 2.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 0.8 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.2 1.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.6 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 2.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 6.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 14.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 15.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 17.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.3 GO:0016208 AMP binding(GO:0016208)
0.1 8.2 GO:0004620 phospholipase activity(GO:0004620)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 4.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0031432 titin binding(GO:0031432)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 2.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 4.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 18.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 3.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 4.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0008823 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 37.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 17.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 13.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 5.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 8.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 11.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 3.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 5.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 5.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 12.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 5.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 33.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.5 16.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.0 32.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
1.0 34.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.0 3.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 8.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 20.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 11.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 5.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 3.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 18.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 35.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 4.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 8.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 6.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 3.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.1 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation