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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxd12

Z-value: 1.08

Motif logo

Transcription factors associated with Hoxd12

Gene Symbol Gene ID Gene Info
ENSMUSG00000001823.6 Hoxd12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd12mm39_v1_chr2_+_74505350_74505357-0.181.2e-01Click!

Activity profile of Hoxd12 motif

Sorted Z-values of Hoxd12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd12

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_77255099 11.84 ENSMUST00000184138.8
ENSMUST00000184006.8
ENSMUST00000185144.8
ENSMUST00000034910.16
muscular LMNA-interacting protein
chr9_-_77255069 11.12 ENSMUST00000184848.8
ENSMUST00000184415.8
muscular LMNA-interacting protein
chr19_-_45800730 8.78 ENSMUST00000086993.11
Kv channel-interacting protein 2
chr9_-_77255171 8.14 ENSMUST00000185039.8
muscular LMNA-interacting protein
chr11_-_99134885 7.94 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr3_-_126792056 7.85 ENSMUST00000044443.15
ankyrin 2, brain
chr15_-_8740218 7.59 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8739893 7.48 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_42070517 6.71 ENSMUST00000206105.2
ENSMUST00000153147.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_+_125192514 6.28 ENSMUST00000032487.14
ENSMUST00000100942.9
ENSMUST00000063588.11
vesicle-associated membrane protein 1
chr15_+_81820954 6.13 ENSMUST00000038757.8
ENSMUST00000230633.2
cold shock domain containing C2, RNA binding
chr14_+_26616514 5.89 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr10_+_86599836 5.82 ENSMUST00000218802.2
predicted gene, 49358
chr5_-_69699965 5.29 ENSMUST00000031045.10
Yip1 domain family, member 7
chr4_+_148085179 5.27 ENSMUST00000103230.5
natriuretic peptide type A
chr17_+_72088281 5.18 ENSMUST00000229874.2
CAP-GLY domain containing linker protein family, member 4
chr3_-_122828592 4.95 ENSMUST00000029761.14
myozenin 2
chr19_-_50667079 4.72 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chr17_-_52133594 4.64 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr3_+_8574420 4.54 ENSMUST00000029002.9
stathmin-like 2
chr9_+_110948492 4.53 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr3_-_154760978 4.46 ENSMUST00000064076.6
TNNI3 interacting kinase
chr3_-_117153802 4.37 ENSMUST00000197743.2
phospholipid phosphatase related 4
chr1_+_128069677 4.19 ENSMUST00000187023.7
R3H domain containing 1
chr2_+_155453103 4.06 ENSMUST00000092995.6
myosin, heavy chain 7B, cardiac muscle, beta
chr5_-_69699932 4.05 ENSMUST00000202423.2
Yip1 domain family, member 7
chr3_+_75981577 3.93 ENSMUST00000038364.15
follistatin-like 5
chr3_+_67799510 3.77 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr12_-_69838004 3.75 ENSMUST00000221646.2
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr19_-_6964988 3.74 ENSMUST00000130048.8
ENSMUST00000025914.7
vascular endothelial growth factor B
chr8_-_47805383 3.71 ENSMUST00000110367.10
storkhead box 2
chr1_-_69147185 3.59 ENSMUST00000121473.8
erb-b2 receptor tyrosine kinase 4
chr17_+_6025861 3.50 ENSMUST00000142409.8
ENSMUST00000061091.14
synaptojanin 2
chr17_-_82045800 3.39 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_-_118246332 3.30 ENSMUST00000017610.10
tissue inhibitor of metalloproteinase 2
chr1_-_46927230 3.12 ENSMUST00000185520.2
solute carrier family 39 (zinc transporter), member 10
chr3_-_141637245 3.02 ENSMUST00000106232.8
bone morphogenetic protein receptor, type 1B
chr8_+_45960931 2.95 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr18_-_35348049 2.93 ENSMUST00000091636.5
ENSMUST00000236680.2
leucine rich repeat transmembrane neuronal 2
chr17_-_36207965 2.92 ENSMUST00000150056.2
ENSMUST00000156817.2
ENSMUST00000146451.8
ENSMUST00000148482.8
RIKEN cDNA 2310061I04 gene
chr17_+_6026015 2.92 ENSMUST00000115790.8
synaptojanin 2
chrX_-_42363663 2.90 ENSMUST00000016294.8
teneurin transmembrane protein 1
chr17_-_91400142 2.85 ENSMUST00000160800.9
neurexin I
chr2_+_65760477 2.81 ENSMUST00000176109.8
cysteine-serine-rich nuclear protein 3
chr2_+_65676176 2.79 ENSMUST00000053910.10
cysteine-serine-rich nuclear protein 3
chr11_-_118246566 2.71 ENSMUST00000155707.3
tissue inhibitor of metalloproteinase 2
chr19_+_24853039 2.71 ENSMUST00000073080.7
predicted gene 10053
chr15_+_8997480 2.65 ENSMUST00000227191.3
RAN binding protein 3-like
chr5_+_107645626 2.65 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr12_+_55883101 2.64 ENSMUST00000059250.8
breast cancer metastasis-suppressor 1-like
chr18_+_37864045 2.62 ENSMUST00000192535.2
protocadherin gamma subfamily B, 5
chr3_-_26386609 2.60 ENSMUST00000193603.6
neuroligin 1
chr10_-_42459624 2.52 ENSMUST00000019938.11
nuclear receptor subfamily 2, group E, member 1
chr8_+_45960804 2.50 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr7_+_30264835 2.50 ENSMUST00000043850.14
IGF-like family receptor 1
chrX_+_35459557 2.48 ENSMUST00000115258.9
zinc finger, CCHC domain containing 12
chrX_+_35459589 2.45 ENSMUST00000048067.10
zinc finger, CCHC domain containing 12
chr12_+_103524690 2.40 ENSMUST00000187155.7
protein phosphatase 4, regulatory subunit 4
chrX_+_35459601 2.40 ENSMUST00000115257.8
zinc finger, CCHC domain containing 12
chrM_+_3906 2.38 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr1_+_128069716 2.36 ENSMUST00000187557.2
R3H domain containing 1
chr11_+_29413734 2.31 ENSMUST00000155854.8
coiled coil domain containing 88A
chr2_-_66240408 2.29 ENSMUST00000112366.8
sodium channel, voltage-gated, type I, alpha
chr3_+_103482591 2.22 ENSMUST00000090697.11
ENSMUST00000239027.2
synaptotagmin VI
chr3_+_66893280 2.20 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chrX_+_35459621 2.19 ENSMUST00000115256.2
zinc finger, CCHC domain containing 12
chrX_+_139357362 2.19 ENSMUST00000033809.4
phosphoribosyl pyrophosphate synthetase 1
chr14_-_36641270 2.15 ENSMUST00000182797.8
coiled-coil serine rich 2
chr1_-_176041498 2.14 ENSMUST00000111167.2
phospholipase D family, member 5
chr14_-_67106037 2.10 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr15_+_81629258 2.07 ENSMUST00000109554.3
ENSMUST00000230946.2
zinc finger CCCH type containing 7B
chr9_-_103569984 2.03 ENSMUST00000049452.15
transmembrane protein 108
chrM_+_7758 2.01 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr14_-_36641470 2.00 ENSMUST00000182042.2
coiled-coil serine rich 2
chr9_-_89620461 1.93 ENSMUST00000060700.4
ENSMUST00000185470.3
ankyrin repeat domain 34C
chr10_-_30531832 1.91 ENSMUST00000217138.2
ENSMUST00000217644.2
ENSMUST00000216172.2
nuclear receptor coactivator 7
chrM_+_7779 1.89 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr9_+_65268304 1.88 ENSMUST00000147185.3
ubiquitin-associated protein 1-like
chr8_-_25528972 1.88 ENSMUST00000084031.6
HtrA serine peptidase 4
chr15_+_81821112 1.83 ENSMUST00000135663.2
cold shock domain containing C2, RNA binding
chr1_-_163141278 1.80 ENSMUST00000027878.14
paired related homeobox 1
chr4_+_136011969 1.77 ENSMUST00000144217.8
zinc finger protein 46
chrX_-_142716200 1.75 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr4_+_43641262 1.75 ENSMUST00000123351.8
ENSMUST00000128549.3
natriuretic peptide receptor 2
chr10_-_30531768 1.72 ENSMUST00000092610.12
nuclear receptor coactivator 7
chr8_-_70355208 1.72 ENSMUST00000110167.5
NADH:ubiquinone oxidoreductase subunit A13
chr13_-_21826688 1.71 ENSMUST00000205631.3
olfactory receptor 11
chr10_+_45453907 1.70 ENSMUST00000037044.13
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr10_+_69623262 1.69 ENSMUST00000183240.2
ankyrin 3, epithelial
chr13_-_23806530 1.67 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr17_-_36208265 1.65 ENSMUST00000148721.8
RIKEN cDNA 2310061I04 gene
chr5_-_24235646 1.64 ENSMUST00000197617.5
ENSMUST00000030849.13
family with sequence similarity 126, member A
chr3_+_66892979 1.63 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chr10_-_35587888 1.56 ENSMUST00000080898.4
S-adenosylmethionine decarboxylase 2
chr10_+_119828821 1.54 ENSMUST00000105261.9
glutamate receptor interacting protein 1
chr1_-_28819331 1.53 ENSMUST00000059937.5
predicted gene 597
chr4_+_136012019 1.51 ENSMUST00000130223.8
zinc finger protein 46
chr2_+_73102269 1.47 ENSMUST00000090813.6
trans-acting transcription factor 9
chr15_+_36179676 1.47 ENSMUST00000171205.3
sperm associated antigen 1
chr17_+_3447465 1.46 ENSMUST00000072156.7
T cell lymphoma invasion and metastasis 2
chr4_-_154721288 1.39 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr14_-_31503869 1.38 ENSMUST00000227089.2
ankyrin repeat domain 28
chr3_+_66893031 1.37 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr19_+_60744385 1.35 ENSMUST00000088237.6
nanos C2HC-type zinc finger 1
chr5_+_119970733 1.32 ENSMUST00000202723.4
T-box 5
chr10_+_116013256 1.25 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr10_+_43400074 1.25 ENSMUST00000057649.8
ENSMUST00000216543.2
predicted gene 9803
chr19_+_22425565 1.21 ENSMUST00000037901.14
transient receptor potential cation channel, subfamily M, member 3
chr5_+_20112500 1.12 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_43632368 1.09 ENSMUST00000222651.2
RAN binding protein 9
chr17_+_74111823 1.07 ENSMUST00000024860.9
EH-domain containing 3
chr1_+_163875783 1.03 ENSMUST00000027874.6
selectin, endothelial cell
chr9_-_123778334 1.00 ENSMUST00000071404.5
chemokine (C-C motif) receptor 1-like 1
chr5_-_74692327 0.98 ENSMUST00000072857.13
ENSMUST00000113542.9
ENSMUST00000151474.3
Sec1 family domain containing 2
chr10_+_116013122 0.97 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr17_+_35278011 0.96 ENSMUST00000007255.13
ENSMUST00000174493.8
dimethylarginine dimethylaminohydrolase 2
chr13_+_83672389 0.95 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr1_-_74639723 0.95 ENSMUST00000127938.8
ENSMUST00000154874.8
ring finger protein 25
chr10_-_25076008 0.95 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr5_+_143864993 0.95 ENSMUST00000172367.3
predicted gene, 42421
chr4_+_31964082 0.92 ENSMUST00000037607.11
ENSMUST00000080933.13
ENSMUST00000108183.8
ENSMUST00000108184.3
mitogen-activated protein kinase kinase kinase 7
chr3_+_121838076 0.90 ENSMUST00000013995.13
ATP-binding cassette, sub-family A (ABC1), member 4
chr12_+_33197692 0.90 ENSMUST00000077456.13
ENSMUST00000110824.9
ataxin 7-like 1
chr3_+_103482547 0.90 ENSMUST00000121834.8
synaptotagmin VI
chr10_-_38998272 0.86 ENSMUST00000136546.8
family with sequence similarity 229, member B
chr5_+_31212165 0.82 ENSMUST00000202795.4
ENSMUST00000201182.4
ENSMUST00000200953.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr4_-_83203388 0.75 ENSMUST00000150522.8
tetratricopeptide repeat domain 39B
chr3_-_19217174 0.75 ENSMUST00000029125.10
armadillo repeat containing 1
chr1_+_132128701 0.73 ENSMUST00000189062.2
LEM domain containing 1
chr4_-_82423944 0.69 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr7_-_102408573 0.67 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
olfactory receptor 560
olfactory receptor 78
chr3_+_40978804 0.66 ENSMUST00000099121.10
La ribonucleoprotein domain family, member 1B
chr19_-_43741363 0.66 ENSMUST00000045562.6
cytochrome c oxidase assembly protein 15
chr10_+_42459772 0.65 ENSMUST00000105497.8
ENSMUST00000144806.8
osteopetrosis associated transmembrane protein 1
chr8_+_45960855 0.64 ENSMUST00000141039.8
sorbin and SH3 domain containing 2
chr1_-_128030148 0.61 ENSMUST00000086614.12
zinc finger, RAN-binding domain containing 3
chr2_-_131194754 0.60 ENSMUST00000059372.11
ring finger protein 24
chr9_+_109641348 0.60 ENSMUST00000200555.5
serine peptidase inhibitor, Kazal type 8
chr14_+_31807760 0.58 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
oxidoreductase NAD-binding domain containing 1
chr1_+_46464625 0.58 ENSMUST00000189749.7
dynein, axonemal, heavy chain 7C
chr7_-_100232276 0.56 ENSMUST00000152876.3
ENSMUST00000150042.8
ENSMUST00000132888.9
mitochondrial ribosomal protein L48
chrX_-_71961890 0.54 ENSMUST00000152200.2
centrin 2
chr19_+_26725589 0.54 ENSMUST00000207812.2
ENSMUST00000175791.9
ENSMUST00000207118.2
ENSMUST00000209085.2
ENSMUST00000112637.10
ENSMUST00000207054.2
ENSMUST00000208589.2
ENSMUST00000176475.9
ENSMUST00000176698.9
ENSMUST00000207832.2
ENSMUST00000177252.9
ENSMUST00000208712.2
ENSMUST00000208186.2
ENSMUST00000208806.2
ENSMUST00000208027.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_-_84854841 0.53 ENSMUST00000236689.2
predicted gene, 17266
chr6_+_90179768 0.53 ENSMUST00000078371.6
vomeronasal 1 receptor, A8
chr6_-_38230890 0.51 ENSMUST00000117556.8
ENSMUST00000169256.5
RIKEN cDNA D630045J12 gene
chr14_-_68771138 0.51 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr5_+_31212110 0.47 ENSMUST00000013773.12
ENSMUST00000201838.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr11_-_102210568 0.47 ENSMUST00000173870.8
upstream binding transcription factor, RNA polymerase I
chr17_+_71326542 0.45 ENSMUST00000179759.3
myomesin 1
chr17_+_35235552 0.44 ENSMUST00000007245.8
ENSMUST00000172499.2
von Willebrand factor A domain containing 7
chr4_-_82423511 0.43 ENSMUST00000050872.15
ENSMUST00000064770.9
nuclear factor I/B
chr7_+_89780785 0.43 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr2_-_35994072 0.43 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chr3_-_87676273 0.42 ENSMUST00000174776.8
platelet endothelial aggregation receptor 1
chr13_+_25127127 0.41 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chrX_+_105964224 0.39 ENSMUST00000060576.8
lysophosphatidic acid receptor 4
chr13_-_53627110 0.38 ENSMUST00000021922.10
msh homeobox 2
chr17_-_47169380 0.37 ENSMUST00000233455.2
BRD4 interacting chromatin remodeling complex associated protein like
chr18_-_3281752 0.36 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr10_-_67972401 0.35 ENSMUST00000218532.2
AT rich interactive domain 5B (MRF1-like)
chr14_+_33774640 0.35 ENSMUST00000226211.2
anthrax toxin receptor-like
chr18_+_44249254 0.33 ENSMUST00000212114.2
predicted gene, 37797
chr17_+_71326510 0.32 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr3_-_154036180 0.29 ENSMUST00000177846.8
LIM homeobox protein 8
chr1_+_59296065 0.28 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr5_-_25047577 0.28 ENSMUST00000030787.9
Ras homolog enriched in brain
chr16_-_35589726 0.26 ENSMUST00000023554.9
solute carrier family 49 member 4
chr16_+_57173632 0.26 ENSMUST00000099667.3
filamin A interacting protein 1-like
chr4_-_133695264 0.26 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr14_-_31807552 0.25 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
diphthamine biosynthesis 3
chr1_+_173986288 0.24 ENSMUST00000068403.4
olfactory receptor 420
chr14_+_54413727 0.24 ENSMUST00000103701.2
T cell receptor alpha joining 41
chr14_+_53048391 0.24 ENSMUST00000103646.5
T cell receptor alpha variable 10D
chr3_-_87676239 0.23 ENSMUST00000173184.2
ENSMUST00000172621.8
ENSMUST00000174759.8
ENSMUST00000172590.8
ENSMUST00000079083.12
platelet endothelial aggregation receptor 1
chr5_-_138185686 0.19 ENSMUST00000110936.8
TATA-box binding protein associated factor 6
chr11_-_109363406 0.18 ENSMUST00000168740.3
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr15_+_39255185 0.18 ENSMUST00000228839.2
regulating synaptic membrane exocytosis 2
chr12_-_73093953 0.14 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr18_-_3281727 0.14 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chr2_-_35994819 0.12 ENSMUST00000148852.4
LIM homeobox protein 6
chrX_-_103244784 0.12 ENSMUST00000118314.8
neurite extension and migration factor
chr4_+_109092459 0.10 ENSMUST00000106631.9
calreticulin 4
chrX_-_142716085 0.09 ENSMUST00000087313.10
doublecortin
chr5_-_31359559 0.09 ENSMUST00000202929.2
ENSMUST00000201231.2
ENSMUST00000114590.8
zinc finger protein 513
chr11_-_101785181 0.08 ENSMUST00000057054.8
mesenchyme homeobox 1
chr17_+_38104420 0.08 ENSMUST00000216051.3
olfactory receptor 123
chr10_+_89906956 0.08 ENSMUST00000183109.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_+_40092216 0.06 ENSMUST00000218134.2
ENSMUST00000216720.2
ENSMUST00000214763.2
olfactory receptor 986
chr10_+_129153986 0.05 ENSMUST00000215503.2
olfactory receptor 780
chr2_-_85478663 0.05 ENSMUST00000099920.2
olfactory receptor 1002
chr4_-_82423985 0.04 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr14_-_48900192 0.04 ENSMUST00000122009.8
orthodenticle homeobox 2
chr2_-_18053158 0.03 ENSMUST00000066885.6
SKI/DACH domain containing 1
chr3_+_5815863 0.02 ENSMUST00000192045.2
predicted pseudogene 8797

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 15.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.0 6.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
1.6 9.5 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.3 5.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
1.3 8.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
1.1 4.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.9 4.5 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.9 3.6 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.9 7.8 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.9 2.6 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.7 3.7 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.7 2.2 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.7 2.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.6 31.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.6 2.5 GO:0021764 amygdala development(GO:0021764)
0.6 3.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.6 2.4 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.5 3.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.5 1.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 2.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.5 1.4 GO:0098749 cerebellar neuron development(GO:0098749)
0.4 1.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.4 2.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 3.4 GO:0071313 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.4 2.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 6.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 6.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 6.7 GO:0071420 cellular response to histamine(GO:0071420)
0.3 1.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 3.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.9 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.2 0.7 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.2 3.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 4.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.2 2.0 GO:0097106 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 4.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.3 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 2.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.9 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 6.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.4 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 1.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 3.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.0 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.4 GO:0010982 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 6.1 GO:0046677 response to antibiotic(GO:0046677)
0.1 4.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.4 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 2.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 8.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 5.7 GO:0030239 myofibril assembly(GO:0030239)
0.1 5.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0072107 myotome development(GO:0061055) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 3.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.0 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 4.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 2.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0007099 centriole replication(GO:0007099)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 1.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.3 GO:0070820 tertiary granule(GO:0070820)
0.5 2.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.5 6.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.5 5.3 GO:0042629 mast cell granule(GO:0042629)
0.4 1.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 35.7 GO:0016605 PML body(GO:0016605)
0.2 3.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 4.1 GO:0097512 cardiac myofibril(GO:0097512)
0.2 5.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 4.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 8.6 GO:0031430 M band(GO:0031430)
0.1 1.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 2.6 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 3.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 18.5 GO:0043197 dendritic spine(GO:0043197)
0.1 8.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 14.5 GO:0030426 growth cone(GO:0030426)
0.0 5.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.0 14.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 9.6 GO:0016607 nuclear speck(GO:0016607)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 5.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 15.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.8 8.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.2 3.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.1 3.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.0 4.9 GO:0051373 FATZ binding(GO:0051373)
0.8 6.7 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.6 4.5 GO:0031013 troponin I binding(GO:0031013)
0.5 2.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.5 6.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.4 1.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 2.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.4 3.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 0.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.3 4.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 1.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 6.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 9.5 GO:0032183 SUMO binding(GO:0032183)
0.3 3.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 5.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.6 GO:0019808 polyamine binding(GO:0019808)
0.2 1.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 33.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 4.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 4.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 6.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 9.3 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 7.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 7.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.9 GO:0016208 AMP binding(GO:0016208)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 4.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 2.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 8.1 GO:0008017 microtubule binding(GO:0008017)
0.0 4.6 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 5.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.9 GO:0043130 ubiquitin binding(GO:0043130)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.9 PID BMP PATHWAY BMP receptor signaling
0.1 5.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 5.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 7.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 6.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 6.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 6.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 15.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 4.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 6.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK