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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxd8

Z-value: 0.98

Motif logo

Transcription factors associated with Hoxd8

Gene Symbol Gene ID Gene Info
ENSMUSG00000027102.5 Hoxd8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd8mm39_v1_chr2_+_74534959_745349920.482.3e-05Click!

Activity profile of Hoxd8 motif

Sorted Z-values of Hoxd8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_63036096 9.19 ENSMUST00000092888.11
fructose bisphosphatase 1
chr18_+_4165832 6.79 ENSMUST00000025076.10
lysozyme-like 1
chr1_+_177557380 6.51 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr12_-_64521464 5.10 ENSMUST00000059833.8
fibrous sheath CABYR binding protein
chr11_-_116572116 5.09 ENSMUST00000144398.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr3_+_18002574 5.01 ENSMUST00000029080.5
cysteine-rich perinuclear theca 12
chr2_+_110427643 4.99 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr1_+_88093726 4.95 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr12_+_31440842 4.89 ENSMUST00000167432.8
solute carrier family 26, member 3
chr4_+_52596266 4.86 ENSMUST00000029995.6
topoisomerase I binding, arginine/serine-rich like
chr18_+_4165856 4.71 ENSMUST00000120837.2
lysozyme-like 1
chr14_+_96118660 4.54 ENSMUST00000228913.2
ENSMUST00000045892.3
spermatid associated like
chr6_+_30610973 4.52 ENSMUST00000062758.11
carboxypeptidase A5
chr10_+_23770586 4.40 ENSMUST00000041416.8
vanin 1
chr6_+_30611028 4.27 ENSMUST00000115138.8
carboxypeptidase A5
chr9_-_105022272 4.23 ENSMUST00000190661.2
ENSMUST00000035180.5
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2
chr4_+_109092610 4.19 ENSMUST00000106628.8
calreticulin 4
chr4_+_148985584 4.12 ENSMUST00000147270.2
castor zinc finger 1
chr13_+_24023428 3.96 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
solute carrier family 17 (sodium phosphate), member 3
chr5_+_87148697 3.83 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr3_+_94280101 3.64 ENSMUST00000029795.10
RAR-related orphan receptor gamma
chr10_+_97318223 3.62 ENSMUST00000163448.4
decorin
chr1_+_87983099 3.54 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_106866678 3.51 ENSMUST00000112724.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr1_-_186947618 3.44 ENSMUST00000110945.4
ENSMUST00000183931.8
ENSMUST00000027908.13
spermatogenesis associated 17
chr3_-_75072319 3.40 ENSMUST00000124618.2
zinc finger, B-box domain containing
chr19_-_46661321 3.36 ENSMUST00000026012.8
cytochrome P450, family 17, subfamily a, polypeptide 1
chr16_-_69660606 3.26 ENSMUST00000076500.14
spermatogenesis associated glutamate (E)-rich protein 2
chr15_-_57128522 3.07 ENSMUST00000137764.2
ENSMUST00000022995.13
solute carrier family 22 (organic cation transporter), member 22
chr13_+_24023386 2.99 ENSMUST00000039721.14
solute carrier family 17 (sodium phosphate), member 3
chr17_-_28779678 2.92 ENSMUST00000114785.3
ENSMUST00000025062.5
colipase, pancreatic
chr10_-_108535970 2.78 ENSMUST00000218023.2
predicted gene 5136
chr5_-_23889591 2.76 ENSMUST00000198549.2
serine/arginine-rich protein specific kinase 2
chr6_+_24733239 2.76 ENSMUST00000031690.6
hyaluronoglucosaminidase 6
chr18_+_11766333 2.75 ENSMUST00000115861.9
retinoblastoma binding protein 8, endonuclease
chr14_+_26722319 2.74 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr8_-_65489834 2.64 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr1_+_9618173 2.63 ENSMUST00000144177.8
alcohol dehydrogenase, iron containing, 1
chr7_+_45271229 2.61 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr4_+_109092459 2.61 ENSMUST00000106631.9
calreticulin 4
chr19_-_46661501 2.58 ENSMUST00000236174.2
cytochrome P450, family 17, subfamily a, polypeptide 1
chr8_-_65489791 2.56 ENSMUST00000124790.8
apelin receptor early endogenous ligand
chr13_+_49761506 2.53 ENSMUST00000021822.7
osteoglycin
chr4_-_96673423 2.47 ENSMUST00000107071.2
predicted gene 12695
chr5_-_103777145 2.45 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr3_-_96359622 2.45 ENSMUST00000093126.11
ENSMUST00000098841.4
cDNA sequence BC107364
chr1_-_186947651 2.42 ENSMUST00000183819.8
spermatogenesis associated 17
chr1_+_87983189 2.40 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr11_+_117700479 2.40 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
synaptogyrin 2
predicted gene 20708
chrX_-_125723491 2.35 ENSMUST00000081074.5
RIKEN cDNA 4932411N23 gene
chr7_+_134870237 2.35 ENSMUST00000210697.2
ENSMUST00000097983.5
neuropeptide S
chr18_-_43610829 2.28 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr7_-_12829100 2.25 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr1_-_134477400 2.21 ENSMUST00000172898.2
MGAT4 family, member E
chr5_+_29400981 2.14 ENSMUST00000160888.8
ENSMUST00000159272.8
ENSMUST00000001247.12
ENSMUST00000161398.8
ENSMUST00000160246.8
ring finger protein 32
chr10_-_103072141 2.14 ENSMUST00000123364.2
ENSMUST00000166240.8
ENSMUST00000020043.12
leucine-rich repeats and IQ motif containing 1
chr3_-_30194559 2.10 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr7_-_44711771 2.08 ENSMUST00000210101.2
ENSMUST00000209219.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr9_+_80072361 2.07 ENSMUST00000184480.8
myosin VI
chr5_-_86780277 2.05 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr8_-_22396428 2.03 ENSMUST00000051965.5
defensin beta 11
chr11_-_59466995 1.97 ENSMUST00000215339.2
ENSMUST00000214351.2
olfactory receptor 222
chr10_-_127843377 1.96 ENSMUST00000219447.2
ENSMUST00000219780.2
ENSMUST00000219707.2
ENSMUST00000219953.2
ENSMUST00000219183.2
hydroxysteroid (17-beta) dehydrogenase 6
chr1_+_180878797 1.90 ENSMUST00000036819.7
RIKEN cDNA 9130409I23 gene
chr5_+_65505657 1.89 ENSMUST00000031096.11
klotho beta
chr9_+_80072274 1.82 ENSMUST00000035889.15
ENSMUST00000113268.8
myosin VI
chr7_+_140343652 1.75 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr9_-_15212849 1.75 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chrX_-_21041892 1.74 ENSMUST00000096511.5
predicted gene, 21876
chr8_+_46463633 1.74 ENSMUST00000110381.9
Lrp2 binding protein
chr9_-_55419442 1.68 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr2_+_89757653 1.59 ENSMUST00000213720.3
ENSMUST00000102609.3
olfactory receptor 1258
chr7_-_80055168 1.51 ENSMUST00000107362.10
ENSMUST00000135306.3
furin (paired basic amino acid cleaving enzyme)
chr9_+_21634779 1.49 ENSMUST00000034713.9
low density lipoprotein receptor
chr10_+_116881246 1.48 ENSMUST00000073834.5
leucine rich repeat containing 10
chrY_+_65387652 1.46 ENSMUST00000178198.2
predicted gene, 20736
chr1_-_126758369 1.44 ENSMUST00000112583.8
ENSMUST00000094609.10
NCK-associated protein 5
chr7_+_30193047 1.42 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chrX_-_105884178 1.42 ENSMUST00000062010.10
retrotransposon Gag like 3
chr4_-_132125510 1.41 ENSMUST00000136711.2
ENSMUST00000084249.11
phosphatase and actin regulator 4
chr4_+_109092829 1.39 ENSMUST00000030285.8
calreticulin 4
chr16_+_14407073 1.35 ENSMUST00000100165.4
RIKEN cDNA A630010A05 gene
chrY_+_79332266 1.34 ENSMUST00000178063.2
predicted gene, 20916
chrY_+_52778041 1.34 ENSMUST00000178673.2
predicted gene, 21258
chr1_+_88234454 1.29 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr2_+_110551976 1.28 ENSMUST00000090332.5
mucin 15
chr15_-_96929086 1.28 ENSMUST00000230086.2
solute carrier family 38, member 4
chrY_-_35875442 1.27 ENSMUST00000180332.2
predicted gene, 20896
chrY_+_84109980 1.27 ENSMUST00000177775.2
predicted gene, 21095
chr7_+_130633776 1.26 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chrY_+_55211732 1.26 ENSMUST00000180249.2
predicted gene, 20931
chr10_-_126866682 1.23 ENSMUST00000040560.11
Ts translation elongation factor, mitochondrial
chr11_-_99265721 1.22 ENSMUST00000006963.3
keratin 28
chrY_-_40270796 1.20 ENSMUST00000177713.2
predicted gene, 21865
chr2_+_152528955 1.19 ENSMUST00000062148.9
malignant T cell amplified sequence 2
chr3_+_93107517 1.19 ENSMUST00000098884.4
filaggrin family member 2
chr2_+_178072324 1.19 ENSMUST00000108912.9
ENSMUST00000042092.9
cadherin-like 26
chr15_+_99192968 1.15 ENSMUST00000128352.8
ENSMUST00000145482.8
pre-mRNA processing factor 40B
chr8_+_22329942 1.14 ENSMUST00000006745.4
defensin beta 2
chr9_+_38240356 1.13 ENSMUST00000214155.2
ENSMUST00000212354.3
olfactory receptor 25
chr16_-_75382905 1.13 ENSMUST00000062721.11
lipase, member I
chr14_+_47536075 1.12 ENSMUST00000227554.2
mitogen-activated protein kinase 1 interacting protein 1-like
chr4_+_145397238 1.11 ENSMUST00000105738.9
zinc finger protein 980
chrY_+_55729767 1.10 ENSMUST00000177834.2
predicted gene, 21858
chr1_+_107288928 1.09 ENSMUST00000191425.7
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr2_+_128704867 1.08 ENSMUST00000110324.8
fibulin 7
chr9_+_54446268 1.08 ENSMUST00000060242.12
SH2 domain containing 7
chr14_+_55797443 1.02 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr3_-_144555062 1.02 ENSMUST00000159989.2
chloride channel accessory 3B
chr10_+_34265969 0.99 ENSMUST00000105511.2
collagen, type X, alpha 1
chrY_+_80146479 0.99 ENSMUST00000179811.2
predicted gene, 21760
chr19_-_12868022 0.93 ENSMUST00000081236.3
olfactory receptor 1446
chr1_+_58841808 0.91 ENSMUST00000190213.2
caspase 8
chr2_-_151510453 0.90 ENSMUST00000180195.8
ENSMUST00000096439.4
RAD21-like (S. pombe)
chr2_-_88854443 0.90 ENSMUST00000099799.5
olfactory receptor 1217
chr17_+_46807637 0.89 ENSMUST00000046497.8
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr6_-_141719536 0.89 ENSMUST00000148411.2
predicted gene 5724
chr2_-_163314480 0.88 ENSMUST00000109418.2
fat storage-inducing transmembrane protein 2
chr2_+_83554868 0.84 ENSMUST00000111740.9
integrin alpha V
chr9_+_72714156 0.83 ENSMUST00000055535.9
protogenin
chr14_+_55797468 0.82 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr10_+_129298547 0.80 ENSMUST00000077836.3
olfactory receptor 787
chr6_-_129077867 0.80 ENSMUST00000032258.8
C-type lectin domain family 2, member e
chr6_-_30936013 0.79 ENSMUST00000101589.5
Kruppel-like factor 14
chr17_+_74796473 0.79 ENSMUST00000024873.7
Yip1 domain family, member 4
chr10_+_129691236 0.78 ENSMUST00000204622.3
olfactory receptor 813
chr10_-_75946790 0.78 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr1_-_126758520 0.77 ENSMUST00000162646.8
NCK-associated protein 5
chr3_-_96104886 0.76 ENSMUST00000016087.4
bolA-like 1 (E. coli)
chr5_+_68189116 0.75 ENSMUST00000094715.8
glutaredoxin, cysteine rich 1
chr16_-_19443851 0.73 ENSMUST00000079891.4
olfactory receptor 171
chr2_+_85868891 0.73 ENSMUST00000218397.2
olfactory receptor 1033
chr2_-_85632888 0.71 ENSMUST00000217410.3
ENSMUST00000216425.3
olfactory receptor 1016
chr6_+_41331039 0.70 ENSMUST00000072103.7
trypsin 10
chr10_-_126866658 0.69 ENSMUST00000120547.2
ENSMUST00000152054.8
Ts translation elongation factor, mitochondrial
chr16_-_19425453 0.67 ENSMUST00000078603.3
ENSMUST00000218837.2
olfactory receptor 170
chr11_-_99979052 0.66 ENSMUST00000107419.2
keratin 32
chr2_+_110551927 0.66 ENSMUST00000111017.9
mucin 15
chr14_+_26616514 0.65 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr6_+_121983720 0.64 ENSMUST00000081777.8
murinoglobulin 2
chrY_-_35085749 0.63 ENSMUST00000180170.2
predicted gene, 20855
chr8_-_117809188 0.62 ENSMUST00000109093.9
ENSMUST00000098375.6
polycystic kidney disease 1 like 2
chr2_+_152511381 0.59 ENSMUST00000125366.8
ENSMUST00000109825.8
ENSMUST00000089059.9
ENSMUST00000079247.4
histocompatibility 13
chr1_+_178233640 0.58 ENSMUST00000027775.9
EF-hand calcium binding domain 2
chr1_-_144427302 0.57 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr2_+_87725306 0.57 ENSMUST00000217436.2
olfactory receptor 1153
chr2_+_83554741 0.57 ENSMUST00000028499.11
integrin alpha V
chr3_-_69767208 0.56 ENSMUST00000171529.4
ENSMUST00000051239.13
serine palmitoyltransferase, small subunit B
chr3_+_142300601 0.56 ENSMUST00000029936.5
guanylate binding protein 2b
chr17_-_56343625 0.56 ENSMUST00000003268.11
SH3-domain GRB2-like 1
chr14_+_69585036 0.54 ENSMUST00000064831.6
ectonucleoside triphosphate diphosphohydrolase 4
chr8_-_19114826 0.51 ENSMUST00000075504.3
defensin beta 39
chr11_-_87783073 0.49 ENSMUST00000213672.2
ENSMUST00000213928.2
olfactory receptor 462
chr2_+_110551685 0.48 ENSMUST00000111016.9
mucin 15
chr9_-_40015750 0.48 ENSMUST00000213858.2
olfactory receptor 984
chr13_+_65298054 0.47 ENSMUST00000214214.2
olfactory receptor 466
chr5_+_88523967 0.45 ENSMUST00000073363.2
amelotin
chr15_-_101422054 0.42 ENSMUST00000230067.3
predicted gene, 49425
chr18_-_70409277 0.39 ENSMUST00000239144.2
predicted gene, 36255
chr19_-_13828056 0.39 ENSMUST00000208493.3
olfactory receptor 1501
chr2_+_89642395 0.38 ENSMUST00000214508.2
olfactory receptor 1255
chr17_+_79919267 0.38 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr3_-_95778679 0.36 ENSMUST00000142437.2
ENSMUST00000067298.5
mitochondrial ribosomal protein S21
chr15_-_35155896 0.35 ENSMUST00000067033.8
ENSMUST00000018476.14
serine/threonine kinase 3
chr11_-_74238498 0.35 ENSMUST00000080365.6
olfactory receptor 411
chr2_-_88909981 0.35 ENSMUST00000213724.2
olfactory receptor 1219
chr1_-_14380032 0.34 ENSMUST00000187790.2
EYA transcriptional coactivator and phosphatase 1
chr1_-_166509404 0.33 ENSMUST00000148677.2
ENSMUST00000027843.11
flavin containing monooxygenase 9
chr2_-_73410632 0.32 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr7_+_103628383 0.30 ENSMUST00000098185.2
olfactory receptor 635
chr3_+_20011405 0.30 ENSMUST00000108325.9
ceruloplasmin
chr4_+_115099237 0.30 ENSMUST00000118278.2
cytochrome P450, family 4, subfamily a, polypeptide 29
chr9_+_111011327 0.28 ENSMUST00000216430.2
leucine rich repeat (in FLII) interacting protein 2
chr7_-_103191732 0.27 ENSMUST00000215663.2
olfactory receptor 612
chr4_+_118521590 0.24 ENSMUST00000217013.2
olfactory receptor 62
chr14_-_50476340 0.23 ENSMUST00000059565.2
olfactory receptor 731
chr2_+_83554770 0.22 ENSMUST00000141725.3
integrin alpha V
chr6_-_3399451 0.22 ENSMUST00000120087.6
sterile alpha motif domain containing 9-like
chr10_+_129297731 0.21 ENSMUST00000213329.2
olfactory receptor 787
chr2_+_87686206 0.21 ENSMUST00000217376.2
olfactory receptor 1151
chr19_-_11833365 0.21 ENSMUST00000079875.4
olfactory receptor 1418
chr8_+_34089597 0.20 ENSMUST00000009774.11
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr13_+_22474090 0.19 ENSMUST00000228382.2
ENSMUST00000228557.2
ENSMUST00000226245.2
ENSMUST00000227516.2
vomeronasal 1 receptor 196
chr17_+_37978659 0.19 ENSMUST00000216551.2
olfactory receptor 118
chr17_-_56343531 0.19 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr5_+_48529671 0.19 ENSMUST00000196950.5
ENSMUST00000030968.7
RIKEN cDNA 5730480H06 gene
chr7_+_102526329 0.17 ENSMUST00000098216.2
olfactory receptor 568
chr2_+_88479038 0.17 ENSMUST00000120518.4
olfactory receptor 1192, pseudogene 1
chr2_+_85677374 0.17 ENSMUST00000215347.3
olfactory receptor 1020
chr1_-_138776315 0.17 ENSMUST00000112030.9
LIM homeobox protein 9
chr10_-_129565161 0.15 ENSMUST00000204717.3
ENSMUST00000216794.2
ENSMUST00000217219.2
olfactory receptor 805
chr17_-_8366536 0.15 ENSMUST00000231927.2
ribonuclease T2A
chr6_+_65502344 0.15 ENSMUST00000212375.2
TNFAIP3 interacting protein 3
chr14_+_47535717 0.14 ENSMUST00000166743.9
mitogen-activated protein kinase 1 interacting protein 1-like
chr17_+_37977879 0.14 ENSMUST00000215811.2
olfactory receptor 118
chr2_-_111820618 0.13 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
olfactory receptor 1309
chr16_+_33614715 0.10 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr9_+_111011388 0.10 ENSMUST00000217117.2
leucine rich repeat (in FLII) interacting protein 2
chr9_-_117843228 0.10 ENSMUST00000187803.3
zinc finger, CW type with PWWP domain 2
chr5_-_38649291 0.09 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.4 4.1 GO:0061076 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.9 10.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 5.1 GO:0097503 sialylation(GO:0097503)
0.7 11.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 3.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.5 1.6 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.5 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 1.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 6.9 GO:0015747 urate transport(GO:0015747)
0.5 3.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 2.4 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.4 1.5 GO:0090472 dibasic protein processing(GO:0090472)
0.4 1.5 GO:0090118 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 1.4 GO:0061386 closure of optic fissure(GO:0061386)
0.3 3.6 GO:0072615 interleukin-17 secretion(GO:0072615)
0.3 4.9 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.3 2.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 5.9 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 2.7 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 4.4 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 1.2 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 3.9 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.4 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 2.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.3 GO:0050955 thermoception(GO:0050955)
0.1 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.9 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.9 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 2.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.8 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.4 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.6 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 1.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.7 GO:0017144 drug metabolic process(GO:0017144)
0.1 2.9 GO:0032094 response to food(GO:0032094)
0.1 0.8 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 5.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 2.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.8 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.3 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 1.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.6 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 7.4 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 4.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.6 GO:0006818 hydrogen transport(GO:0006818)
0.0 3.7 GO:0006814 sodium ion transport(GO:0006814)
0.0 3.7 GO:0042742 defense response to bacterium(GO:0042742)
0.0 1.5 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.4 1.7 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.4 1.6 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.3 2.8 GO:0070552 BRISC complex(GO:0070552)
0.2 0.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 5.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 3.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 0.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 4.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 2.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 3.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 7.4 GO:0000800 lateral element(GO:0000800)
0.1 1.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 2.1 GO:0016235 aggresome(GO:0016235)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 6.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 5.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.6 11.5 GO:0003796 lysozyme activity(GO:0003796)
0.6 3.6 GO:0008142 oxysterol binding(GO:0008142)
0.6 9.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.6 5.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 4.4 GO:0034235 GPI anchor binding(GO:0034235)
0.5 1.9 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.4 2.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 1.3 GO:0035375 zymogen binding(GO:0035375)
0.4 14.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 4.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 8.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 5.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.3 2.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.3 2.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 2.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 3.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.2 1.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 2.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 2.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.6 GO:0019002 GMP binding(GO:0019002)
0.2 1.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 1.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 5.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 3.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.4 GO:0071949 FAD binding(GO:0071949)
0.0 2.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 5.2 GO:0005179 hormone activity(GO:0005179)
0.0 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 2.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 9.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 2.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.2 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.8 PID ATM PATHWAY ATM pathway
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.9 PID FGF PATHWAY FGF signaling pathway
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 3.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.3 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 5.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 5.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 7.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 9.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.7 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 2.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo