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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hoxd9

Z-value: 0.51

Motif logo

Transcription factors associated with Hoxd9

Gene Symbol Gene ID Gene Info
ENSMUSG00000043342.10 Hoxd9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd9mm39_v1_chr2_+_74528071_745280970.218.2e-02Click!

Activity profile of Hoxd9 motif

Sorted Z-values of Hoxd9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd9

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_6673167 5.34 ENSMUST00000163073.2
FYN binding protein
chr1_-_138103021 3.15 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr1_-_138102972 3.11 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr14_+_66043281 2.89 ENSMUST00000022612.10
PDZ binding kinase
chr19_-_57185988 2.47 ENSMUST00000099294.9
actin-binding LIM protein 1
chr3_-_14843512 2.06 ENSMUST00000094365.11
carbonic anhydrase 1
chr16_-_75706161 2.05 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_+_60503051 1.94 ENSMUST00000192757.6
ENSMUST00000193518.6
ENSMUST00000195817.3
muscleblind like splicing factor 1
chr13_+_49697919 1.85 ENSMUST00000177948.2
ENSMUST00000021820.14
asporin
chr19_-_57185928 1.83 ENSMUST00000111544.8
actin-binding LIM protein 1
chr4_-_129472328 1.83 ENSMUST00000052835.9
family with sequence similarity 167, member B
chr6_+_41095752 1.79 ENSMUST00000103269.3
T cell receptor beta, variable 12-2
chr19_-_57185861 1.70 ENSMUST00000111550.8
actin-binding LIM protein 1
chr3_-_144525255 1.68 ENSMUST00000029929.12
chloride channel accessory 3A2
chr1_-_82746169 1.67 ENSMUST00000027331.3
transmembrane 4 L six family member 20
chr14_+_54000594 1.63 ENSMUST00000103589.6
T cell receptor alpha variable 14-3
chr15_-_98832403 1.61 ENSMUST00000077577.8
tubulin, alpha 1B
chr10_-_18890281 1.60 ENSMUST00000146388.2
tumor necrosis factor, alpha-induced protein 3
chr7_-_119078330 1.54 ENSMUST00000207460.2
uromodulin
chr4_-_94538329 1.43 ENSMUST00000107101.2
leucine rich repeat containing 19
chr12_+_117807224 1.42 ENSMUST00000021592.16
cell division cycle associated 7 like
chr6_+_70192384 1.36 ENSMUST00000103383.3
immunoglobulin kappa chain variable 6-25
chr5_-_21087023 1.35 ENSMUST00000118174.8
putative homeodomain transcription factor 2
chr2_+_14179324 1.27 ENSMUST00000077517.9
transmembrane protein 236
chr6_+_149226891 1.26 ENSMUST00000189837.2
retroelement silencing factor 1
chrX_-_133442596 1.21 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr3_-_144511566 1.12 ENSMUST00000199029.2
chloride channel accessory 3A2
chrX_+_56257374 1.11 ENSMUST00000033466.2
CD40 ligand
chr16_-_48232770 1.10 ENSMUST00000212197.2
predicted gene 5485
chr9_-_64080161 1.09 ENSMUST00000176299.8
ENSMUST00000130127.8
ENSMUST00000176794.8
ENSMUST00000177045.8
zwilch kinetochore protein
chr5_-_87572060 1.07 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chr14_+_74973081 1.01 ENSMUST00000177283.8
esterase D/formylglutathione hydrolase
chr12_-_118265103 1.01 ENSMUST00000222314.2
ENSMUST00000026367.11
trans-acting transcription factor 4
chr6_+_122530758 1.00 ENSMUST00000043301.14
activation-induced cytidine deaminase
chr6_-_68840015 0.99 ENSMUST00000103336.2
immunoglobulin kappa chain variable 1-88
chr1_-_171854818 0.99 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr7_-_112987770 0.98 ENSMUST00000079793.7
parathyroid hormone
chr6_+_38918327 0.93 ENSMUST00000160963.2
thromboxane A synthase 1, platelet
chr11_+_67061908 0.93 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr14_+_53853772 0.92 ENSMUST00000180972.3
T cell receptor alpha variable 12-2
chr14_+_54453748 0.92 ENSMUST00000103736.2
T cell receptor alpha joining 4
chr7_+_89814713 0.91 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chrX_+_41241049 0.89 ENSMUST00000128799.3
stromal antigen 2
chr5_-_18054702 0.87 ENSMUST00000165232.8
CD36 molecule
chr3_-_75177378 0.86 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr2_-_84255602 0.86 ENSMUST00000074262.9
calcitonin receptor-like
chr6_-_69800923 0.85 ENSMUST00000103368.3
immunoglobulin kappa chain variable 5-43
chr3_-_115923098 0.83 ENSMUST00000196449.5
vascular cell adhesion molecule 1
chr5_+_18167547 0.83 ENSMUST00000030561.9
guanine nucleotide binding protein, alpha transducing 3
chr6_-_87510200 0.82 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr11_+_23234644 0.80 ENSMUST00000150750.3
exportin 1
chr11_-_99482165 0.79 ENSMUST00000104930.2
keratin associated protein 1-3
chr14_+_53859114 0.78 ENSMUST00000103657.6
T cell receptor alpha variable 12-3
chr6_+_83985684 0.76 ENSMUST00000203803.3
ENSMUST00000204591.3
ENSMUST00000113823.8
ENSMUST00000153860.4
dysferlin
chr7_-_84328553 0.72 ENSMUST00000069537.3
ENSMUST00000207865.2
ENSMUST00000178385.9
ENSMUST00000208782.2
zinc finger, AN1-type domain 6
chr3_-_144555062 0.69 ENSMUST00000159989.2
chloride channel accessory 3B
chrX_-_165992145 0.69 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr17_-_78991691 0.68 ENSMUST00000145480.2
striatin, calmodulin binding protein
chr9_+_32305259 0.68 ENSMUST00000172015.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr3_+_35808269 0.67 ENSMUST00000029257.15
ATPase, class VI, type 11B
chrX_+_55493325 0.67 ENSMUST00000079663.7
predicted gene 2174
chr2_+_11176891 0.64 ENSMUST00000028118.9
protein kinase C, theta
chr9_+_77959206 0.63 ENSMUST00000024104.9
glial cells missing homolog 1
chr11_+_67061837 0.62 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr1_-_154975376 0.61 ENSMUST00000055322.6
immediate early response 5
chr1_-_86039692 0.60 ENSMUST00000027431.7
5-hydroxytryptamine (serotonin) receptor 2B
chr4_-_112291169 0.60 ENSMUST00000058605.3
selection and upkeep of intraepithelial T cells 9
chr11_-_80030735 0.59 ENSMUST00000136996.2
transcription elongation factor, mitochondrial
chr18_+_42669322 0.58 ENSMUST00000236418.2
transcription elongation regulator 1 (CA150)
chr12_-_113589576 0.57 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr2_-_76700830 0.57 ENSMUST00000138542.2
titin
chrX_+_132751729 0.57 ENSMUST00000033602.9
tenomodulin
chr5_-_120950570 0.55 ENSMUST00000117193.8
2'-5' oligoadenylate synthetase 1C
chr11_-_99996452 0.54 ENSMUST00000107416.3
keratin 36
chr9_+_43222104 0.54 ENSMUST00000034511.7
tripartite motif-containing 29
chr6_+_67993691 0.54 ENSMUST00000103314.3
immunoglobulin kappa chain variable 1-122
chr1_-_128030148 0.53 ENSMUST00000086614.12
zinc finger, RAN-binding domain containing 3
chr14_+_54429118 0.53 ENSMUST00000103713.2
T cell receptor alpha joining 28
chr12_+_31488208 0.52 ENSMUST00000001254.6
solute carrier family 26, member 3
chrX_-_165992311 0.52 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr10_-_93727003 0.52 ENSMUST00000180840.8
methionine aminopeptidase 2
chr14_+_43951187 0.46 ENSMUST00000094051.6
predicted gene 7324
chrM_+_11735 0.46 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr13_-_100453124 0.45 ENSMUST00000042220.3
NLR family, apoptosis inhibitory protein 6
chr3_+_30656204 0.45 ENSMUST00000192715.6
myoneurin
chr1_-_97689263 0.45 ENSMUST00000171129.8
diphosphoinositol pentakisphosphate kinase 2
chr19_+_56536685 0.45 ENSMUST00000071423.7
NHL repeat containing 2
chr6_+_18848600 0.43 ENSMUST00000201141.3
LSM8 homolog, U6 small nuclear RNA associated
chr6_-_41291634 0.42 ENSMUST00000064324.12
trypsin 5
chr2_+_85648823 0.42 ENSMUST00000214416.2
olfactory receptor 1018
chr3_+_32490525 0.42 ENSMUST00000108242.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr1_-_144427302 0.41 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr5_-_69699932 0.41 ENSMUST00000202423.2
Yip1 domain family, member 7
chr6_+_83985495 0.41 ENSMUST00000113821.8
dysferlin
chr7_+_127661807 0.40 ENSMUST00000064821.14
integrin alpha M
chrX_-_133652080 0.39 ENSMUST00000113194.8
armadillo repeat containing, X-linked 6
chr12_-_118930130 0.39 ENSMUST00000035515.5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr13_-_21330037 0.38 ENSMUST00000216039.3
olfactory receptor 1368
chr9_-_18297277 0.38 ENSMUST00000166825.8
N-acetylated alpha-linked acidic dipeptidase 2
chr7_+_30264835 0.37 ENSMUST00000043850.14
IGF-like family receptor 1
chr12_+_59176506 0.37 ENSMUST00000175912.8
ENSMUST00000176892.8
MIA SH3 domain ER export factor 2
chrX_-_133652140 0.36 ENSMUST00000052431.12
armadillo repeat containing, X-linked 6
chr16_+_29884153 0.35 ENSMUST00000023171.8
hes family bHLH transcription factor 1
chr1_+_180158035 0.35 ENSMUST00000070181.7
inositol 1,4,5-trisphosphate 3-kinase B
chr2_-_87568666 0.34 ENSMUST00000099848.2
olfactory receptor 1138
chr7_+_120450406 0.34 ENSMUST00000143322.9
ENSMUST00000106488.3
eukaryotic elongation factor-2 kinase
chr7_-_103320398 0.34 ENSMUST00000062144.4
olfactory receptor 624
chr18_+_31922173 0.33 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr3_-_129834788 0.33 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr5_-_87402659 0.33 ENSMUST00000075858.4
UDP glucuronosyltransferase 2 family, polypeptide B37
chr14_-_122202508 0.32 ENSMUST00000227267.2
G protein-coupled receptor 183
chr8_-_84976330 0.31 ENSMUST00000019506.9
DNA segment, Chr 8, ERATO Doi 738, expressed
chr10_+_115405891 0.31 ENSMUST00000173620.2
RIKEN cDNA A930009A15 gene
chr9_-_105973975 0.30 ENSMUST00000121963.3
collagen, type VI, alpha 4
chr13_-_32960379 0.30 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr5_-_100521343 0.29 ENSMUST00000182433.8
Sec31 homolog A (S. cerevisiae)
chr9_-_38577138 0.29 ENSMUST00000076542.2
olfactory receptor 917
chr5_-_62923463 0.28 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_65650269 0.28 ENSMUST00000121661.8
small integral membrane protein 14
chr6_+_41179484 0.28 ENSMUST00000195087.2
T cell receptor beta, variable 21
chr3_+_20043315 0.28 ENSMUST00000173779.2
ceruloplasmin
chr5_+_136982100 0.28 ENSMUST00000111094.8
ENSMUST00000111097.8
fission, mitochondrial 1
chr5_-_86345729 0.27 ENSMUST00000031172.9
ENSMUST00000113372.2
gonadotropin releasing hormone receptor
chr12_+_59176543 0.27 ENSMUST00000069430.15
ENSMUST00000177370.8
MIA SH3 domain ER export factor 2
chr5_+_88523967 0.27 ENSMUST00000073363.2
amelotin
chr3_+_32490300 0.27 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr14_+_63284438 0.26 ENSMUST00000067990.8
ENSMUST00000111203.2
defensin beta 42
chr1_-_140111018 0.26 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr10_+_129153986 0.26 ENSMUST00000215503.2
olfactory receptor 780
chr1_+_88128323 0.25 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr1_-_4430481 0.25 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chr8_-_62576140 0.24 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr14_-_56137697 0.23 ENSMUST00000111325.5
short chain dehydrogenase/reductase family 39U, member 1
chr2_-_89779008 0.23 ENSMUST00000214846.2
olfactory receptor 1259
chr10_+_23952398 0.23 ENSMUST00000051133.6
trace amine-associated receptor 8A
chr2_-_87524291 0.22 ENSMUST00000077471.5
olfactory receptor 1136
chr2_-_87543523 0.22 ENSMUST00000214209.2
olfactory receptor 1137
chr16_-_22847808 0.21 ENSMUST00000115349.9
kininogen 2
chr10_-_81102740 0.21 ENSMUST00000046114.5
mitochondrial ribosomal protein L54
chr19_+_45433899 0.20 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr2_-_115895202 0.19 ENSMUST00000110906.9
Meis homeobox 2
chr5_-_120950549 0.19 ENSMUST00000125547.2
2'-5' oligoadenylate synthetase 1C
chr3_-_106729898 0.19 ENSMUST00000059486.3
olfactory receptor 266
chr4_-_137084973 0.19 ENSMUST00000030417.10
ENSMUST00000051477.13
cell division cycle 42
chr1_-_140111138 0.19 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr14_-_75991903 0.18 ENSMUST00000049168.9
component of oligomeric golgi complex 3
chr1_+_106908709 0.18 ENSMUST00000027564.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr2_-_151586063 0.18 ENSMUST00000109869.2
proteasome (prosome, macropain) inhibitor subunit 1
chr4_-_43710231 0.18 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr4_-_73869071 0.18 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr2_+_88470886 0.17 ENSMUST00000217379.2
ENSMUST00000120598.3
olfactory receptor 1191, pseudogene 1
chr10_-_35587888 0.17 ENSMUST00000080898.4
S-adenosylmethionine decarboxylase 2
chr2_-_87467879 0.16 ENSMUST00000216082.2
olfactory receptor 1132
chr13_-_3995349 0.16 ENSMUST00000058610.8
urocortin 3
chr1_+_167425953 0.15 ENSMUST00000015987.10
retinoid X receptor gamma
chr2_+_111355548 0.14 ENSMUST00000217845.3
olfactory receptor 1293, pseudogene
chr11_-_55498559 0.13 ENSMUST00000108853.8
ENSMUST00000075603.5
glycine receptor, alpha 1 subunit
chr11_+_59503792 0.13 ENSMUST00000055276.6
olfactory receptor 225
chr4_+_114020581 0.13 ENSMUST00000079915.10
ENSMUST00000164297.8
selection and upkeep of intraepithelial T cells 11
chr2_+_86338805 0.13 ENSMUST00000076263.2
olfactory receptor 1076
chr8_+_85583611 0.12 ENSMUST00000003906.13
ENSMUST00000109754.2
phenylalanyl-tRNA synthetase, alpha subunit
chr16_-_78887971 0.12 ENSMUST00000023566.11
ENSMUST00000060402.6
transmembrane protease, serine 15
chr15_+_91722458 0.12 ENSMUST00000109277.8
submandibular gland protein C
chr2_+_91357100 0.12 ENSMUST00000111338.10
cytoskeleton associated protein 5
chr7_+_107679062 0.11 ENSMUST00000213601.2
olfactory receptor 481
chr2_+_111311164 0.11 ENSMUST00000120021.5
olfactory receptor 1289
chr1_-_160079007 0.11 ENSMUST00000191909.6
RAB GTPase activating protein 1-like
chr2_-_90123185 0.10 ENSMUST00000117141.4
olfactory receptor 1272
chr11_+_31823096 0.10 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr15_+_91722524 0.10 ENSMUST00000109276.8
ENSMUST00000088555.10
ENSMUST00000100293.9
ENSMUST00000126508.8
ENSMUST00000239545.1
submandibular gland protein C
mucin 19
chr3_+_93052089 0.10 ENSMUST00000107300.7
ENSMUST00000195515.2
cornulin
chr5_-_86521273 0.10 ENSMUST00000031175.12
transmembrane protease, serine 11d
chr7_-_10011933 0.10 ENSMUST00000227719.2
ENSMUST00000228622.2
ENSMUST00000228086.2
vomeronasal 1 receptor 66
chr2_-_89195205 0.10 ENSMUST00000111543.2
ENSMUST00000137692.3
olfactory receptor 1234
chr19_-_13828056 0.10 ENSMUST00000208493.3
olfactory receptor 1501
chr16_-_22847760 0.10 ENSMUST00000039338.13
kininogen 2
chr13_-_81859056 0.10 ENSMUST00000161920.2
ENSMUST00000048993.12
polymerase (RNA) III (DNA directed) polypeptide G
chr2_-_89487877 0.09 ENSMUST00000099768.3
olfactory receptor 1250
chr3_+_5815863 0.09 ENSMUST00000192045.2
predicted pseudogene 8797
chrX_+_94942639 0.09 ENSMUST00000082183.8
zinc finger CCCH-type containing 12B
chr10_-_129107354 0.09 ENSMUST00000204573.3
olfactory receptor 777
chr7_-_104777612 0.09 ENSMUST00000214399.4
olfactory receptor 682, pseudogene 1
chr2_-_87570322 0.08 ENSMUST00000214573.2
olfactory receptor 1138
chr2_-_88587017 0.08 ENSMUST00000099813.2
olfactory receptor 1199
chr2_-_172296662 0.07 ENSMUST00000161334.2
glucosaminyl (N-acetyl) transferase family member 7
chr11_-_58614840 0.07 ENSMUST00000214728.2
olfactory receptor 318
chr2_-_88534814 0.07 ENSMUST00000216928.2
ENSMUST00000216977.2
olfactory receptor 1196
chr2_+_83554770 0.07 ENSMUST00000141725.3
integrin alpha V
chr14_-_54855446 0.07 ENSMUST00000227257.2
ENSMUST00000022803.6
proteasome (prosome, macropain) subunit, beta type 5
chr7_-_12829100 0.06 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr10_-_129463803 0.06 ENSMUST00000204979.3
olfactory receptor 798
chr3_+_103078971 0.06 ENSMUST00000005830.15
breast carcinoma amplified sequence 2
chr16_-_19241884 0.06 ENSMUST00000206110.4
olfactory receptor 165
chr17_+_38459392 0.05 ENSMUST00000113636.2
olfactory receptor 133
chr12_-_30181898 0.05 ENSMUST00000155263.2
thyroid peroxidase
chr2_+_87574098 0.05 ENSMUST00000214723.2
olfactory receptor 1140
chr3_-_49711765 0.05 ENSMUST00000035931.13
protocadherin 18
chr3_-_116505469 0.05 ENSMUST00000153108.6
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr16_-_19385631 0.05 ENSMUST00000090062.2
olfactory receptor 169
chr17_+_78815493 0.05 ENSMUST00000024880.11
ENSMUST00000232859.2
vitrin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.5 1.6 GO:0034147 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.4 1.5 GO:0072218 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.4 1.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.4 1.8 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 1.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 1.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 1.0 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 0.7 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.9 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 0.9 GO:0070543 response to linoleic acid(GO:0070543)
0.2 0.3 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.2 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.6 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.6 GO:0043056 forward locomotion(GO:0043056)
0.1 0.3 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.5 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.6 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.8 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.3 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 2.8 GO:0043276 anoikis(GO:0043276)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 5.3 GO:0045576 mast cell activation(GO:0045576)
0.0 6.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0090135 actin filament branching(GO:0090135)
0.0 2.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 1.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.9 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 2.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.5 GO:0070269 pyroptosis(GO:0070269)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.2 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.7 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.0 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652) regulation of interleukin-3 production(GO:0032672)
0.0 1.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 2.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990423 RZZ complex(GO:1990423)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.2 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 1.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 6.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0034683 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 9.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 0.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 7.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 2.1 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.6 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.5 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.1 0.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 3.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.0 0.6 GO:0051378 serotonin binding(GO:0051378)
0.0 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.6 GO:0016790 thiolester hydrolase activity(GO:0016790)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 12.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 6.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 5.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis