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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Hsf1

Z-value: 0.93

Motif logo

Transcription factors associated with Hsf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022556.12 Hsf1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf1mm39_v1_chr15_+_76361604_763617740.422.2e-04Click!

Activity profile of Hsf1 motif

Sorted Z-values of Hsf1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_157401998 7.36 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
neuronatin
chr12_-_72283465 6.23 ENSMUST00000021497.16
ENSMUST00000137990.2
reticulon 1
chr17_-_45883421 5.14 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr1_+_66360865 4.58 ENSMUST00000114013.8
microtubule-associated protein 2
chr5_-_149559636 4.58 ENSMUST00000201452.4
heat shock 105kDa/110kDa protein 1
chr10_-_80679859 4.57 ENSMUST00000053986.9
leucine rich repeat and Ig domain containing 3
chrX_-_149440388 4.51 ENSMUST00000151403.9
ENSMUST00000087253.11
ENSMUST00000112709.8
ENSMUST00000163969.8
ENSMUST00000087258.10
trophinin
chr9_+_50664207 4.46 ENSMUST00000034562.9
crystallin, alpha B
chrX_-_60229164 4.43 ENSMUST00000166381.3
cerebellar degeneration related antigen 1
chr9_+_50664288 4.36 ENSMUST00000214962.2
ENSMUST00000216755.2
crystallin, alpha B
chr18_+_67266054 4.26 ENSMUST00000236771.2
ENSMUST00000237304.2
ENSMUST00000076605.9
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr9_-_58448224 3.88 ENSMUST00000039788.11
CD276 antigen
chr4_+_43414696 3.72 ENSMUST00000131668.3
RUN and SH3 domain containing 2
chr9_+_18203558 3.53 ENSMUST00000213605.2
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr5_+_66833434 3.52 ENSMUST00000031131.11
ubiquitin carboxy-terminal hydrolase L1
chr15_-_58828321 3.50 ENSMUST00000228067.2
MTSS I-BAR domain containing 1
chr18_+_43897354 3.32 ENSMUST00000187157.7
ENSMUST00000043803.13
ENSMUST00000189750.2
secretoglobin, family 3A, member 2
chr5_-_139470169 3.27 ENSMUST00000150992.2
ENSMUST00000110851.8
ENSMUST00000079996.13
zinc finger, AN1-type domain 2A
chr16_-_20245071 3.25 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr9_+_18203640 3.19 ENSMUST00000217031.2
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr7_-_110462446 3.10 ENSMUST00000033050.5
lymphatic vessel endothelial hyaluronan receptor 1
chr5_-_129864202 3.08 ENSMUST00000136507.4
phosphoserine phosphatase
chr9_-_110818679 3.03 ENSMUST00000084922.6
ENSMUST00000199891.2
receptor transporter protein 3
chr5_-_149559737 3.02 ENSMUST00000200805.4
heat shock 105kDa/110kDa protein 1
chr1_-_55127312 2.81 ENSMUST00000127861.8
ENSMUST00000144077.3
heat shock protein 1 (chaperonin)
chr4_-_136620376 2.78 ENSMUST00000046332.6
complement component 1, q subcomponent, C chain
chr19_-_7017295 2.75 ENSMUST00000025918.9
stress-induced phosphoprotein 1
chr16_-_20245138 2.68 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chrX_-_149440362 2.59 ENSMUST00000148604.2
trophinin
chr5_-_149559792 2.58 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
heat shock 105kDa/110kDa protein 1
chr14_+_66205932 2.51 ENSMUST00000022616.14
clusterin
chr7_-_89590404 2.50 ENSMUST00000153470.9
heat shock protein nuclear import factor
chr4_+_42949814 2.48 ENSMUST00000037872.10
ENSMUST00000098112.9
DnaJ heat shock protein family (Hsp40) member B5
chr5_-_123887434 2.42 ENSMUST00000182955.8
ENSMUST00000182489.8
ENSMUST00000183147.9
ENSMUST00000050827.14
ENSMUST00000057795.12
ENSMUST00000111515.8
ENSMUST00000182309.8
arginine/serine-rich coiled-coil 2
chr18_-_10706701 2.40 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr8_-_45835234 2.36 ENSMUST00000093526.13
family with sequence similarity 149, member A
chr14_-_63430937 2.34 ENSMUST00000225157.2
ENSMUST00000226002.2
ENSMUST00000038229.5
nei like 2 (E. coli)
chr12_-_110662256 2.31 ENSMUST00000149189.2
heat shock protein 90, alpha (cytosolic), class A member 1
chr4_+_155686311 2.27 ENSMUST00000118607.2
solute carrier family 35, member E2
chr6_+_51447317 2.26 ENSMUST00000094623.10
chromobox 3
chr7_-_19043955 2.26 ENSMUST00000207334.2
ENSMUST00000208505.2
ENSMUST00000207716.2
ENSMUST00000208326.2
ENSMUST00000003640.4
FBJ osteosarcoma oncogene B
chr11_+_6510167 2.25 ENSMUST00000109722.9
cerebral cavernous malformation 2
chr7_-_89590230 2.18 ENSMUST00000075010.12
heat shock protein nuclear import factor
chr7_+_140425460 2.17 ENSMUST00000035300.7
secretoglobin, family 1C, member 1
chr5_+_129864044 2.17 ENSMUST00000201414.5
chaperonin containing Tcp1, subunit 6a (zeta)
chr2_+_109523908 2.16 ENSMUST00000111045.9
brain derived neurotrophic factor
chr3_+_117368483 2.10 ENSMUST00000039564.11
ENSMUST00000238937.2
phospholipid phosphatase related 5
chr9_+_18203421 2.06 ENSMUST00000001825.9
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr18_+_37637317 2.06 ENSMUST00000052179.8
protocadherin beta 20
chr11_-_116226175 2.03 ENSMUST00000036215.8
forkhead box J1
chr10_+_59159118 2.02 ENSMUST00000009789.15
ENSMUST00000092512.11
ENSMUST00000105466.3
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr17_-_50401305 2.02 ENSMUST00000113195.8
raftlin lipid raft linker 1
chr7_-_89590334 2.00 ENSMUST00000207309.2
ENSMUST00000130609.3
heat shock protein nuclear import factor
chr8_+_88999031 1.97 ENSMUST00000169037.9
adenylate cyclase 7
chr16_+_22926504 1.96 ENSMUST00000187168.7
ENSMUST00000232287.2
ENSMUST00000077605.12
eukaryotic translation initiation factor 4A2
chr8_+_36956345 1.91 ENSMUST00000171777.2
tRNA methyltransferase 9B
chr3_+_79498663 1.89 ENSMUST00000029382.13
peptidylprolyl isomerase D (cyclophilin D)
chr4_+_155685830 1.86 ENSMUST00000105608.9
solute carrier family 35, member E2
chr1_+_179788675 1.85 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr5_+_30486375 1.82 ENSMUST00000101448.5
dynein regulatory complex subunit 1
chr15_+_81284333 1.77 ENSMUST00000163754.9
ENSMUST00000041609.11
X-prolyl aminopeptidase 3, mitochondrial
chr5_-_149559667 1.75 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr7_-_46365108 1.75 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr9_-_53617508 1.66 ENSMUST00000068449.4
RAB39, member RAS oncogene family
chr16_+_22926162 1.65 ENSMUST00000023599.13
ENSMUST00000168891.8
eukaryotic translation initiation factor 4A2
chr4_+_152262583 1.64 ENSMUST00000075363.10
acyl-CoA thioesterase 7
chr1_+_57813759 1.60 ENSMUST00000167971.8
ENSMUST00000170139.8
ENSMUST00000171699.8
ENSMUST00000164302.8
spermatogenesis associated, serine-rich 2-like
chr9_+_92339422 1.58 ENSMUST00000034941.9
phospholipid scramblase 4
chr1_+_66361252 1.58 ENSMUST00000123647.8
microtubule-associated protein 2
chr16_-_55755208 1.55 ENSMUST00000121129.8
ENSMUST00000023270.14
centrosomal protein 97
chr9_+_40712562 1.55 ENSMUST00000117557.8
heat shock protein 8
chr6_+_58808733 1.53 ENSMUST00000126292.8
ENSMUST00000031823.12
hect domain and RLD 3
chr7_-_99002430 1.51 ENSMUST00000094154.6
serine (or cysteine) peptidase inhibitor, clade H, member 1
chrX_-_73067514 1.50 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
interleukin-1 receptor-associated kinase 1
chr19_-_29790352 1.49 ENSMUST00000099525.5
RAN binding protein 6
chrX_-_76968668 1.43 ENSMUST00000063127.4
RIKEN cDNA 5430402E10 gene
chr10_-_61219229 1.43 ENSMUST00000020289.10
phosphatase domain containing, paladin 1
chr4_+_17853452 1.36 ENSMUST00000029881.10
matrix metallopeptidase 16
chr14_+_34097474 1.36 ENSMUST00000227130.2
multimerin 2
chr9_+_22322802 1.33 ENSMUST00000058868.9
RIKEN cDNA 9530077C05 gene
chr4_+_40722461 1.31 ENSMUST00000030118.10
DnaJ heat shock protein family (Hsp40) member A1
chr15_-_81283795 1.29 ENSMUST00000023039.15
suppression of tumorigenicity 13
chr11_-_5049082 1.23 ENSMUST00000063232.7
Ewing sarcoma breakpoint region 1
chr8_-_49009043 1.21 ENSMUST00000110343.3
teneurin transmembrane protein 3
chr5_+_29940935 1.17 ENSMUST00000114839.8
ENSMUST00000198694.5
ENSMUST00000012734.10
ENSMUST00000196528.5
DnaJ heat shock protein family (Hsp40) member B6
chr11_-_23448030 1.13 ENSMUST00000020529.13
AHA1, activator of heat shock protein ATPase 2
chr11_-_23447866 1.10 ENSMUST00000128559.2
ENSMUST00000147157.8
ENSMUST00000109539.8
AHA1, activator of heat shock protein ATPase 2
chr11_+_82802079 1.10 ENSMUST00000018989.14
ENSMUST00000164945.3
unc-45 myosin chaperone B
chr3_-_106454898 1.07 ENSMUST00000121231.8
ENSMUST00000141525.2
choline/ethanolaminephosphotransferase 1
chr12_-_110662677 1.04 ENSMUST00000124156.8
heat shock protein 90, alpha (cytosolic), class A member 1
chr15_+_28203872 1.04 ENSMUST00000067048.8
dynein, axonemal, heavy chain 5
chrX_-_73067351 1.03 ENSMUST00000114353.10
ENSMUST00000101458.9
interleukin-1 receptor-associated kinase 1
chr3_+_117368876 1.01 ENSMUST00000106473.5
phospholipid phosphatase related 5
chr7_-_99002204 1.00 ENSMUST00000208292.2
ENSMUST00000207989.2
ENSMUST00000208749.2
ENSMUST00000169437.9
ENSMUST00000208119.2
ENSMUST00000207849.2
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr11_+_70591299 0.98 ENSMUST00000152618.9
ENSMUST00000102554.8
ENSMUST00000094499.11
ENSMUST00000072187.12
ENSMUST00000137119.3
kinesin family member 1C
chr15_-_31601652 0.98 ENSMUST00000161266.2
chaperonin containing Tcp1, subunit 5 (epsilon)
chr9_+_22322875 0.98 ENSMUST00000214436.2
RIKEN cDNA 9530077C05 gene
chr3_-_89309944 0.97 ENSMUST00000057431.6
lens epithelial protein
chr17_+_15261896 0.95 ENSMUST00000226599.2
ENSMUST00000228518.2
ENSMUST00000226213.2
ER membrane associated RNA degradation
chr7_-_19043525 0.94 ENSMUST00000208446.2
FBJ osteosarcoma oncogene B
chr4_+_40722911 0.90 ENSMUST00000164233.8
ENSMUST00000137246.8
ENSMUST00000125442.8
DnaJ heat shock protein family (Hsp40) member A1
chr18_-_36899245 0.84 ENSMUST00000061522.8
DND microRNA-mediated repression inhibitor 1
chr11_-_48836975 0.84 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr16_-_87292592 0.82 ENSMUST00000176750.2
ENSMUST00000175977.8
chaperonin containing Tcp1, subunit 8 (theta)
chr16_-_87292711 0.75 ENSMUST00000176041.8
ENSMUST00000026704.14
chaperonin containing Tcp1, subunit 8 (theta)
chr5_-_86616849 0.75 ENSMUST00000101073.3
transmembrane protease, serine 11a
chr4_-_133273243 0.74 ENSMUST00000030665.7
nudC nuclear distribution protein
chr11_+_83599841 0.71 ENSMUST00000001009.14
WAP four-disulfide core domain 18
chr15_+_31602252 0.71 ENSMUST00000042702.7
ENSMUST00000161061.3
ATP synthase C subunit lysine N-methyltransferase
chr12_+_75355082 0.69 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr16_-_55755160 0.67 ENSMUST00000122280.8
ENSMUST00000121703.3
centrosomal protein 97
chr1_-_55127183 0.66 ENSMUST00000027123.15
heat shock protein 1 (chaperonin)
chr5_-_36853281 0.62 ENSMUST00000031091.13
ENSMUST00000140653.2
DNA segment, Chr 5, ERATO Doi 579, expressed
chr7_+_121666388 0.61 ENSMUST00000033158.6
ubiquitin family domain containing 1
chr2_+_29014106 0.58 ENSMUST00000129544.8
senataxin
chr6_-_136918885 0.57 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_72416531 0.54 ENSMUST00000205335.2
ENSMUST00000206692.2
ENSMUST00000059472.10
methionine adenosyltransferase II, alpha
chr8_-_70411054 0.53 ENSMUST00000211960.2
GATA zinc finger domain containing 2A
chr11_+_49500090 0.53 ENSMUST00000020617.3
FMS-like tyrosine kinase 4
chr15_-_100301124 0.50 ENSMUST00000124324.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr17_-_47321430 0.46 ENSMUST00000113337.10
ENSMUST00000113335.4
ubiquitin protein ligase E3 component n-recognin 2
chr5_+_135916764 0.46 ENSMUST00000005077.7
heat shock protein 1
chr6_-_128803182 0.45 ENSMUST00000204756.3
ENSMUST00000204394.3
ENSMUST00000204423.3
ENSMUST00000204677.2
ENSMUST00000205130.3
ENSMUST00000174544.2
ENSMUST00000172887.8
ENSMUST00000032472.11
predicted gene 44511
killer cell lectin-like receptor subfamily B member 1B
chr8_-_110419867 0.45 ENSMUST00000034164.6
increased sodium tolerance 1 homolog (yeast)
chr1_-_160040286 0.44 ENSMUST00000195654.2
ENSMUST00000014370.11
calcyclin binding protein
chr19_+_13594739 0.43 ENSMUST00000217061.3
ENSMUST00000209005.4
ENSMUST00000208347.3
olfactory receptor 1487
chr9_+_119939414 0.38 ENSMUST00000035106.12
solute carrier family 25, member 38
chr7_+_110628158 0.38 ENSMUST00000005749.6
CTR9 homolog, Paf1/RNA polymerase II complex component
chr5_+_135916847 0.37 ENSMUST00000111155.2
heat shock protein 1
chr9_-_103357564 0.35 ENSMUST00000124310.5
beaded filament structural protein 2, phakinin
chr15_-_81284244 0.34 ENSMUST00000172107.8
ENSMUST00000169204.2
ENSMUST00000163382.2
suppression of tumorigenicity 13
chr7_-_19621833 0.29 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr15_-_31601932 0.29 ENSMUST00000022842.16
chaperonin containing Tcp1, subunit 5 (epsilon)
chr12_+_24881582 0.25 ENSMUST00000221952.2
ENSMUST00000078902.8
ENSMUST00000110942.11
membrane bound O-acyltransferase domain containing 2
chr12_-_104718159 0.25 ENSMUST00000041987.7
dicer 1, ribonuclease type III
chr1_+_57814001 0.25 ENSMUST00000167085.8
spermatogenesis associated, serine-rich 2-like
chr11_-_106469938 0.23 ENSMUST00000103070.3
testis expressed gene 2
chr8_-_49008881 0.23 ENSMUST00000110345.8
teneurin transmembrane protein 3
chr17_+_15261470 0.23 ENSMUST00000097393.11
ER membrane associated RNA degradation
chr2_+_72128239 0.19 ENSMUST00000144111.2
mitogen-activated protein kinase kinase kinase 20
chr6_-_51446850 0.19 ENSMUST00000069949.13
heterogeneous nuclear ribonucleoprotein A2/B1
chr7_+_35285657 0.19 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
ankyrin repeat domain 27 (VPS9 domain)
chr17_+_15230438 0.18 ENSMUST00000097395.5
predicted gene 3435
chr6_-_51446752 0.17 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_-_80347482 0.15 ENSMUST00000085289.12
ENSMUST00000185068.2
ENSMUST00000113250.10
interphotoreceptor matrix proteoglycan 1
chrX_+_76908364 0.15 ENSMUST00000114039.3
predicted gene 14744
chr9_-_105372235 0.11 ENSMUST00000176190.8
ENSMUST00000163879.9
ENSMUST00000112558.10
ENSMUST00000176363.9
ATPase, Ca++-sequestering
chr11_-_5049223 0.10 ENSMUST00000079949.13
Ewing sarcoma breakpoint region 1
chr7_+_92210348 0.09 ENSMUST00000032842.13
ENSMUST00000085017.5
coiled-coil domain containing 90B
chr3_+_93052089 0.08 ENSMUST00000107300.7
ENSMUST00000195515.2
cornulin
chr13_+_44883270 0.07 ENSMUST00000172830.8
jumonji, AT rich interactive domain 2
chr10_-_86541349 0.05 ENSMUST00000020238.14
heat shock protein 90, beta (Grp94), member 1
chr17_+_15230597 0.05 ENSMUST00000232446.2
predicted gene 3435
chr11_-_5049036 0.03 ENSMUST00000102930.10
ENSMUST00000093365.12
ENSMUST00000073308.11
Ewing sarcoma breakpoint region 1
chr17_+_48606948 0.02 ENSMUST00000233092.2
triggering receptor expressed on myeloid cells-like 2
chrX_-_72759748 0.02 ENSMUST00000002091.6
B cell receptor associated protein 31
chr7_-_121666486 0.02 ENSMUST00000033159.4
glutamyl-tRNA synthetase 2, mitochondrial

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000299)
1.7 5.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
1.2 11.9 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
1.2 3.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.9 5.7 GO:0007412 axon target recognition(GO:0007412)
0.8 8.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.7 2.0 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 3.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.6 3.9 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.5 4.3 GO:0009405 pathogenesis(GO:0009405)
0.5 1.5 GO:0097212 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.4 3.0 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.4 2.5 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 1.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4 3.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 1.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 2.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 2.8 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.3 4.5 GO:1904871 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 2.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.3 1.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 2.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 2.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.7 GO:0090383 phagosome acidification(GO:0090383)
0.2 1.6 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 2.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 0.6 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 3.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 2.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 3.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.4 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.4 GO:1990428 miRNA transport(GO:1990428)
0.1 6.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:0009838 abscission(GO:0009838)
0.1 0.8 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 2.9 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0036233 glycine import(GO:0036233)
0.1 6.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 1.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.5 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 3.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 2.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 3.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 3.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 1.8 GO:0003094 glomerular filtration(GO:0003094)
0.1 6.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 3.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.8 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 0.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.3 GO:0071335 regulation of enamel mineralization(GO:0070173) hair follicle cell proliferation(GO:0071335)
0.0 0.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 2.3 GO:0006284 base-excision repair(GO:0006284)
0.0 0.9 GO:0097264 self proteolysis(GO:0097264)
0.0 3.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 5.3 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.5 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.4 GO:0060416 response to growth hormone(GO:0060416)
0.0 5.9 GO:0015711 organic anion transport(GO:0015711)
0.0 0.0 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.7 6.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 9.6 GO:0097512 cardiac myofibril(GO:0097512)
0.5 3.0 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 3.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 2.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3 1.5 GO:0043202 lysosomal lumen(GO:0043202)
0.3 2.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 4.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 6.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 4.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.9 GO:0000502 proteasome complex(GO:0000502)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 6.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 10.7 GO:0005874 microtubule(GO:0005874)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 5.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.8 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 8.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.1 GO:0002135 CTP binding(GO:0002135)
1.1 11.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.9 3.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 1.6 GO:0032564 dATP binding(GO:0032564)
0.7 2.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 6.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 3.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 3.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 3.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 2.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 2.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 3.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 9.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 1.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 3.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 2.5 GO:0051787 misfolded protein binding(GO:0051787)
0.2 9.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 8.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 2.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 4.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 5.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 6.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 3.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 6.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 6.2 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 5.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 3.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.2 PID SHP2 PATHWAY SHP2 signaling
0.0 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.5 9.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 2.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 4.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 2.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis