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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Irf4

Z-value: 1.21

Motif logo

Transcription factors associated with Irf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021356.11 Irf4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf4mm39_v1_chr13_+_30933209_309332900.343.1e-03Click!

Activity profile of Irf4 motif

Sorted Z-values of Irf4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_36293588 11.85 ENSMUST00000060128.7
claudin 23
chr4_-_89229256 10.98 ENSMUST00000097981.6
cyclin dependent kinase inhibitor 2B
chr11_+_69857722 10.36 ENSMUST00000151515.2
claudin 7
chr9_+_44953723 8.35 ENSMUST00000034600.5
myelin protein zero-like 2
chr3_+_3699205 8.04 ENSMUST00000108394.3
hepatocyte nuclear factor 4, gamma
chr19_+_56385531 7.55 ENSMUST00000026062.10
caspase 7
chr13_-_95661726 7.37 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr13_-_100689212 7.28 ENSMUST00000022140.12
occludin
chr13_-_100753419 7.28 ENSMUST00000168772.2
ENSMUST00000163163.9
ENSMUST00000022137.14
MARVEL (membrane-associating) domain containing 2
chr11_+_115353290 7.27 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr13_-_100689105 7.21 ENSMUST00000159459.8
occludin
chr3_+_3573084 7.10 ENSMUST00000108393.8
hepatocyte nuclear factor 4, gamma
chr17_-_7050145 7.05 ENSMUST00000064234.7
ezrin
chr9_-_65330231 6.57 ENSMUST00000065894.7
solute carrier family 51, beta subunit
chr6_-_129077867 6.53 ENSMUST00000032258.8
C-type lectin domain family 2, member e
chr8_+_46338498 6.51 ENSMUST00000034053.7
PDZ and LIM domain 3
chr7_+_79836581 6.47 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr8_+_46338557 6.16 ENSMUST00000210422.2
PDZ and LIM domain 3
chr3_-_30753979 6.07 ENSMUST00000126658.8
ENSMUST00000108263.2
leucine rich repeat containing 31
chr17_+_35481702 6.06 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr4_-_132990362 5.85 ENSMUST00000105908.10
ENSMUST00000030674.8
synaptotagmin-like 1
chr4_-_46536088 5.74 ENSMUST00000102924.3
ENSMUST00000046897.13
tripartite motif-containing 14
chr2_-_173060647 5.61 ENSMUST00000109116.3
ENSMUST00000029018.14
Z-DNA binding protein 1
chr13_-_100753181 5.56 ENSMUST00000225754.2
MARVEL (membrane-associating) domain containing 2
chrX_+_138464065 5.56 ENSMUST00000113027.8
ring finger protein 128
chr11_+_62711057 5.52 ENSMUST00000055006.12
ENSMUST00000072639.10
tripartite motif-containing 16
chr16_-_55659194 5.51 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr7_-_18757461 5.42 ENSMUST00000036018.6
forkhead box A3
chr7_-_4606104 5.29 ENSMUST00000049113.14
protein tyrosine phosphatase, receptor type, H
chr4_-_129132963 4.93 ENSMUST00000097873.10
expressed sequence C77080
chr17_-_29134288 4.88 ENSMUST00000062357.6
BCL2 interacting protein 5
chr14_-_54646917 4.73 ENSMUST00000000984.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr3_+_27371168 4.57 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr11_+_82006001 4.57 ENSMUST00000009329.3
chemokine (C-C motif) ligand 8
chr19_-_57185928 4.49 ENSMUST00000111544.8
actin-binding LIM protein 1
chr7_-_140846328 4.33 ENSMUST00000106023.8
ENSMUST00000097952.9
ENSMUST00000026571.11
interferon regulatory factor 7
chr11_+_62711295 4.28 ENSMUST00000108703.2
tripartite motif-containing 16
chr12_+_119354110 4.24 ENSMUST00000222058.2
metastasis associated in colon cancer 1
chr10_-_111833138 4.21 ENSMUST00000074805.12
GLI pathogenesis-related 1 (glioma)
chr19_-_57185808 4.09 ENSMUST00000111546.8
actin-binding LIM protein 1
chr5_-_104169696 4.06 ENSMUST00000119025.2
hydroxysteroid (17-beta) dehydrogenase 11
chr11_-_3489228 4.06 ENSMUST00000075118.10
ENSMUST00000136243.2
ENSMUST00000020721.15
ENSMUST00000170588.8
smoothelin
chr19_-_57185988 3.99 ENSMUST00000099294.9
actin-binding LIM protein 1
chr11_-_101062111 3.98 ENSMUST00000164474.8
ENSMUST00000043397.14
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_-_24202344 3.87 ENSMUST00000099558.5
ENSMUST00000232956.2
tight junction protein 2
chr6_-_70313491 3.84 ENSMUST00000103388.4
immunoglobulin kappa variable 6-20
chr12_+_111383864 3.67 ENSMUST00000220537.2
ENSMUST00000223050.2
ENSMUST00000072646.8
ENSMUST00000223431.2
ENSMUST00000221144.2
ENSMUST00000222437.2
exocyst complex component 3-like 4
chr3_+_95434093 3.64 ENSMUST00000015667.9
ENSMUST00000116304.3
cathepsin S
chr16_-_43484494 3.62 ENSMUST00000096065.6
T cell immunoreceptor with Ig and ITIM domains
chr3_+_27371206 3.59 ENSMUST00000174840.2
tumor necrosis factor (ligand) superfamily, member 10
chr11_+_48977852 3.59 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr19_-_57185861 3.57 ENSMUST00000111550.8
actin-binding LIM protein 1
chr7_-_89176294 3.56 ENSMUST00000207932.2
protease, serine 23
chr5_-_104169785 3.51 ENSMUST00000031251.16
hydroxysteroid (17-beta) dehydrogenase 11
chr6_-_87312743 3.43 ENSMUST00000042025.12
ENSMUST00000205033.2
anthrax toxin receptor 1
chr11_+_48977888 3.35 ENSMUST00000214804.2
interferon gamma inducible protein 47
chr10_+_82696135 3.34 ENSMUST00000219442.3
thioredoxin reductase 1
chr16_+_35759346 3.25 ENSMUST00000023622.13
poly (ADP-ribose) polymerase family, member 9
chr2_+_38401826 3.10 ENSMUST00000112895.8
NIMA (never in mitosis gene a)-related expressed kinase 6
chr9_-_116004386 2.96 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr19_-_34618135 2.95 ENSMUST00000087357.5
interferon induced protein with tetratricopeptide repeats 1B like 2
chr6_-_87312681 2.94 ENSMUST00000204805.3
anthrax toxin receptor 1
chr10_-_53952686 2.88 ENSMUST00000220088.2
mannosidase 1, alpha
chr10_+_69048464 2.77 ENSMUST00000020101.12
Rho-related BTB domain containing 1
chr15_-_58187556 2.73 ENSMUST00000022985.2
kelch-like 38
chr10_+_94411119 2.73 ENSMUST00000121471.8
transmembrane and coiled coil domains 3
chr2_+_127967951 2.72 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
BCL2-like 11 (apoptosis facilitator)
chr1_+_182236728 2.66 ENSMUST00000117245.2
transformation related protein 53 binding protein 2
chrX_-_9335525 2.65 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr1_-_163141278 2.65 ENSMUST00000027878.14
paired related homeobox 1
chr1_-_174749379 2.63 ENSMUST00000055294.4
gremlin 2, DAN family BMP antagonist
chrX_+_158086253 2.63 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr19_+_34618271 2.60 ENSMUST00000102824.4
interferon-induced protein with tetratricopeptide repeats 1
chr16_-_35759461 2.58 ENSMUST00000081933.14
ENSMUST00000114885.3
deltex 3-like, E3 ubiquitin ligase
chr1_+_57884693 2.57 ENSMUST00000169772.3
spermatogenesis associated, serine-rich 2-like
chr11_+_43365103 2.56 ENSMUST00000173002.8
ENSMUST00000057679.10
C1q and tumor necrosis factor related protein 2
chr8_-_25086976 2.49 ENSMUST00000033956.7
indoleamine 2,3-dioxygenase 1
chrX_-_107877909 2.47 ENSMUST00000101283.4
ENSMUST00000150434.8
bromodomain and WD repeat domain containing 3
chr11_-_101442663 2.42 ENSMUST00000017290.11
breast cancer 1, early onset
chr6_+_53264255 2.41 ENSMUST00000203528.3
cAMP responsive element binding protein 5
chr1_+_16758629 2.39 ENSMUST00000026881.11
lymphocyte antigen 96
chr3_+_89328926 2.36 ENSMUST00000094378.10
ENSMUST00000137793.2
src homology 2 domain-containing transforming protein C1
chr1_-_156766381 2.32 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr3_+_90444613 2.31 ENSMUST00000107335.2
S100 calcium binding protein A16
chr7_-_4448631 2.29 ENSMUST00000008579.14
retinol dehydrogenase 13 (all-trans and 9-cis)
chr2_+_38401655 2.26 ENSMUST00000054234.10
ENSMUST00000112902.8
NIMA (never in mitosis gene a)-related expressed kinase 6
chr1_-_164763091 2.26 ENSMUST00000027860.8
chemokine (C motif) ligand 1
chr9_+_5345405 2.26 ENSMUST00000027009.11
caspase 12
chr3_+_90444537 2.25 ENSMUST00000098911.10
S100 calcium binding protein A16
chr9_+_5345450 2.25 ENSMUST00000151332.2
caspase 12
chr1_-_156766351 2.24 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr12_-_114073050 2.21 ENSMUST00000103472.4
immunoglobulin heavy variable V9-2
chrX_-_105884178 2.20 ENSMUST00000062010.10
retrotransposon Gag like 3
chr4_-_156285247 2.12 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chr7_-_65020655 2.05 ENSMUST00000032729.8
tight junction protein 1
chr10_-_12424623 2.01 ENSMUST00000219003.2
utrophin
chr14_-_30348153 2.01 ENSMUST00000112211.9
ENSMUST00000112210.11
protein kinase C, delta
chr14_+_14475188 2.00 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr3_-_142101418 2.00 ENSMUST00000029941.16
ENSMUST00000058626.9
PDZ and LIM domain 5
chr10_+_21758083 1.96 ENSMUST00000120509.8
serum/glucocorticoid regulated kinase 1
chr1_-_192883642 1.91 ENSMUST00000192020.6
TRAF3 interacting protein 3
chr8_+_79236051 1.83 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr15_-_76127600 1.83 ENSMUST00000165738.8
ENSMUST00000075689.7
poly (ADP-ribose) polymerase family, member 10
chr17_-_35081129 1.82 ENSMUST00000154526.8
complement factor B
chr19_-_4976844 1.81 ENSMUST00000236496.2
dipeptidylpeptidase 3
chr7_-_80037622 1.81 ENSMUST00000206698.2
feline sarcoma oncogene
chr1_+_61677977 1.77 ENSMUST00000075374.10
par-3 family cell polarity regulator beta
chr17_-_35081456 1.71 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr7_+_126895531 1.70 ENSMUST00000170971.8
integrin alpha L
chr13_-_64645606 1.68 ENSMUST00000180282.2
family with sequence similarity 240 member B
chr1_+_160898283 1.67 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr14_+_120513076 1.62 ENSMUST00000088419.13
muscleblind like splicing factor 2
chr5_-_99391073 1.55 ENSMUST00000166484.2
RasGEF domain family, member 1B
chr10_+_18283405 1.53 ENSMUST00000037341.14
NHS-like 1
chr12_-_118930130 1.50 ENSMUST00000035515.5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr10_+_69048506 1.48 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr10_+_28544356 1.47 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
thymocyte selection associated
chr7_+_126895463 1.41 ENSMUST00000106306.9
ENSMUST00000120857.8
integrin alpha L
chr14_+_54436247 1.37 ENSMUST00000103720.2
T cell receptor alpha joining 21
chr15_-_101651534 1.36 ENSMUST00000023710.6
keratin 71
chr11_+_78136569 1.35 ENSMUST00000002133.9
stromal cell derived factor 2
chr6_-_39095144 1.32 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr8_+_105897300 1.32 ENSMUST00000052209.9
ENSMUST00000109392.9
ENSMUST00000109395.8
core binding factor beta
chr14_+_55815879 1.31 ENSMUST00000174563.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_131016573 1.28 ENSMUST00000127987.2
sperm flagellar 1
chr19_-_3955230 1.27 ENSMUST00000145791.8
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr3_-_151953894 1.27 ENSMUST00000196529.5
nexilin
chr4_+_114857348 1.25 ENSMUST00000030490.13
Scl/Tal1 interrupting locus
chr7_+_35285657 1.22 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
ankyrin repeat domain 27 (VPS9 domain)
chr1_+_52158693 1.20 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chr14_+_55815580 1.19 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr7_+_126895423 1.18 ENSMUST00000117762.8
integrin alpha L
chr14_+_55815817 1.15 ENSMUST00000174259.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr3_+_60436570 1.14 ENSMUST00000192607.6
muscleblind like splicing factor 1
chr3_-_57202301 1.14 ENSMUST00000171384.8
transmembrane 4 superfamily member 1
chr1_-_163141230 1.11 ENSMUST00000174397.3
ENSMUST00000075805.13
paired related homeobox 1
chr4_-_123033721 1.09 ENSMUST00000030404.5
peptidylprolyl isomerase E (cyclophilin E)
chr1_-_156766957 1.05 ENSMUST00000171292.8
ENSMUST00000063199.13
ENSMUST00000027886.14
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_16758731 1.02 ENSMUST00000190366.2
lymphocyte antigen 96
chr14_+_55815999 1.02 ENSMUST00000172738.2
ENSMUST00000089619.13
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_-_35179042 0.99 ENSMUST00000217306.2
ENSMUST00000125087.2
ENSMUST00000121564.8
ENSMUST00000063782.12
ENSMUST00000059057.14
family with sequence similarity 118, member B
chr13_-_113182891 0.97 ENSMUST00000231962.2
ENSMUST00000022282.6
glutathione peroxidase 8 (putative)
chrM_+_8603 0.97 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr13_+_38009981 0.97 ENSMUST00000110238.10
ras responsive element binding protein 1
chr1_+_52158599 0.97 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr14_+_34097474 0.96 ENSMUST00000227130.2
multimerin 2
chr15_-_66432938 0.95 ENSMUST00000048372.7
transmembrane protein 71
chr4_-_19922599 0.93 ENSMUST00000029900.6
ATPase, H+ transporting, lysosomal V0 subunit D2
chr6_-_48422447 0.91 ENSMUST00000114564.8
zinc finger protein 467
chr4_-_107035479 0.91 ENSMUST00000058585.14
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr3_+_92325386 0.90 ENSMUST00000029533.3
small proline-rich protein 2J, pseudogene
chr5_-_92653377 0.89 ENSMUST00000031377.9
scavenger receptor class B, member 2
chr14_+_54436898 0.86 ENSMUST00000103721.3
T cell receptor alpha joining 20
chr4_+_114857370 0.84 ENSMUST00000129957.8
Scl/Tal1 interrupting locus
chr19_+_5618096 0.84 ENSMUST00000096318.4
adaptor-related protein complex 5, beta 1 subunit
chrX_-_100266032 0.84 ENSMUST00000120389.8
ENSMUST00000156473.8
ENSMUST00000077876.4
sorting nexin 12
chr6_+_67243967 0.84 ENSMUST00000203436.3
ENSMUST00000205106.3
ENSMUST00000204293.3
ENSMUST00000203077.3
ENSMUST00000204294.3
serpine1 mRNA binding protein 1
chr11_+_119283887 0.82 ENSMUST00000093902.12
ENSMUST00000131035.10
ring finger protein 213
chr13_-_19579961 0.81 ENSMUST00000039694.13
STARD3 N-terminal like
chr9_-_117080869 0.78 ENSMUST00000172564.3
RNA binding motif, single stranded interacting protein
chr14_+_120513106 0.78 ENSMUST00000227012.2
ENSMUST00000167459.3
muscleblind like splicing factor 2
chr1_-_75294234 0.76 ENSMUST00000066668.14
ENSMUST00000185797.7
aspartyl aminopeptidase
chr7_-_80037688 0.76 ENSMUST00000080932.8
feline sarcoma oncogene
chr2_-_152673032 0.75 ENSMUST00000128172.3
BCL2-like 1
chr10_-_52071340 0.74 ENSMUST00000020045.10
Ros1 proto-oncogene
chr8_-_55340024 0.72 ENSMUST00000176866.8
WD repeat domain 17
chr1_-_184464810 0.71 ENSMUST00000048572.7
H2.0-like homeobox
chr17_+_35780977 0.70 ENSMUST00000174525.8
ENSMUST00000068291.7
histocompatibility 2, Q region locus 10
chr13_-_19579898 0.68 ENSMUST00000197565.3
ENSMUST00000221380.2
ENSMUST00000200323.3
ENSMUST00000199924.2
ENSMUST00000222869.2
STARD3 N-terminal like
chr11_+_87938626 0.68 ENSMUST00000107920.10
serine and arginine-rich splicing factor 1
chr19_+_46611826 0.67 ENSMUST00000111855.5
WW domain binding protein 1 like
chr1_+_44158111 0.60 ENSMUST00000155917.8
basic, immunoglobulin-like variable motif containing
chr11_+_87938519 0.59 ENSMUST00000079866.11
serine and arginine-rich splicing factor 1
chr17_-_30831576 0.59 ENSMUST00000235171.2
ENSMUST00000236335.2
ENSMUST00000167624.2
glyoxalase 1
chr8_-_106665060 0.58 ENSMUST00000034369.10
proteasome (prosome, macropain) subunit, beta type 10
chr5_+_147206769 0.53 ENSMUST00000085591.7
pancreatic and duodenal homeobox 1
chr1_-_63726062 0.52 ENSMUST00000090313.5
dystrotelin
chr8_-_46577183 0.45 ENSMUST00000170416.8
sorting nexin 25
chr11_+_46701619 0.45 ENSMUST00000068877.7
T cell immunoglobulin and mucin domain containing 4
chr8_+_62381115 0.43 ENSMUST00000154398.8
ENSMUST00000156980.8
ENSMUST00000093485.3
ENSMUST00000070631.15
DExD/H box helicase 60
chr8_-_85500998 0.43 ENSMUST00000109762.8
nuclear factor I/X
chr1_+_52158721 0.41 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr15_+_102391614 0.38 ENSMUST00000229432.2
poly(rC) binding protein 2
chr1_-_75293942 0.38 ENSMUST00000187075.7
aspartyl aminopeptidase
chr5_-_92496730 0.36 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr12_-_113542610 0.33 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr2_-_9883391 0.32 ENSMUST00000102976.4
GATA binding protein 3
chr11_+_72580823 0.31 ENSMUST00000155998.2
ankyrin repeat and FYVE domain containing 1
chr13_-_81718759 0.31 ENSMUST00000109565.9
adhesion G protein-coupled receptor V1
chr2_+_90770742 0.28 ENSMUST00000005643.14
ENSMUST00000111451.10
ENSMUST00000177642.8
ENSMUST00000068726.13
ENSMUST00000068747.14
CUGBP, Elav-like family member 1
chr19_+_41017714 0.26 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr16_+_43056218 0.22 ENSMUST00000146708.8
zinc finger and BTB domain containing 20
chr14_-_20784625 0.21 ENSMUST00000223679.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr9_-_110886306 0.21 ENSMUST00000195968.2
ENSMUST00000111888.3
chemokine (C-C motif) receptor-like 2
chr16_+_65317389 0.20 ENSMUST00000176330.8
ENSMUST00000004964.15
ENSMUST00000176038.8
POU domain, class 1, transcription factor 1
chr10_+_128542120 0.20 ENSMUST00000054125.9
premelanosome protein
chr2_+_91480513 0.19 ENSMUST00000090614.11
Rho GTPase activating protein 1
chrX_-_162332673 0.16 ENSMUST00000033730.3
gastrin releasing peptide receptor
chr10_-_107555840 0.14 ENSMUST00000050702.9
protein tyrosine phosphatase, receptor type, Q
chr19_+_5618029 0.13 ENSMUST00000235575.2
ENSMUST00000235542.2
adaptor-related protein complex 5, beta 1 subunit

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
1.9 7.6 GO:0006710 androgen catabolic process(GO:0006710)
1.8 7.0 GO:1902896 terminal web assembly(GO:1902896)
1.5 7.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.4 5.4 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
1.3 5.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
1.2 3.6 GO:0034769 basement membrane disassembly(GO:0034769)
1.2 6.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.1 6.4 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.9 2.6 GO:0060300 regulation of cytokine activity(GO:0060300)
0.9 2.6 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.8 2.5 GO:0036269 swimming behavior(GO:0036269)
0.8 14.5 GO:0070673 response to interleukin-18(GO:0070673)
0.8 9.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7 1.5 GO:0043383 negative T cell selection(GO:0043383)
0.7 4.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.7 2.7 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.6 4.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.6 5.6 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.6 3.9 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.5 11.0 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.5 6.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.5 2.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 3.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 2.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 3.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.5 4.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.5 10.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.5 1.8 GO:0010847 regulation of chromatin assembly(GO:0010847) protein poly-ADP-ribosylation(GO:0070212)
0.4 1.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.4 2.4 GO:1990839 response to endothelin(GO:1990839)
0.3 2.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3 5.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.3 2.0 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 2.3 GO:0009644 response to high light intensity(GO:0009644)
0.3 0.8 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 2.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 3.8 GO:0048664 neuron fate determination(GO:0048664)
0.3 4.5 GO:0016540 protein autoprocessing(GO:0016540)
0.2 14.9 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.2 3.7 GO:0051601 exocyst localization(GO:0051601)
0.2 3.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 3.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 8.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 1.0 GO:0030576 Cajal body organization(GO:0030576)
0.2 8.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 0.7 GO:0060154 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) response to cycloheximide(GO:0046898) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2 5.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 2.1 GO:0033504 floor plate development(GO:0033504)
0.2 2.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 1.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 4.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 4.7 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.1 1.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 2.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.0 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 2.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 3.6 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 4.6 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 5.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 14.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 2.6 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.1 0.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.5 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 6.5 GO:0050919 negative chemotaxis(GO:0050919)
0.1 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 5.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 1.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.4 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 8.4 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 1.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.7 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.0 GO:0090051 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 0.6 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 3.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 11.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.9 GO:0007035 vacuolar acidification(GO:0007035)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 8.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 2.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 3.7 GO:0051592 response to calcium ion(GO:0051592)
0.0 2.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.0 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 2.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 1.0 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.5 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.4 12.8 GO:0033010 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.9 4.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.8 2.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.8 26.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.8 4.7 GO:0008537 proteasome activator complex(GO:0008537)
0.5 6.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 3.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 6.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 7.4 GO:0031143 pseudopodium(GO:0031143)
0.3 2.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 3.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 0.9 GO:0043202 lysosomal lumen(GO:0043202)
0.2 7.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 2.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.7 GO:0000145 exocyst(GO:0000145)
0.1 15.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 2.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 7.6 GO:0005811 lipid particle(GO:0005811)
0.1 12.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 9.7 GO:0030018 Z disc(GO:0030018)
0.0 5.2 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 2.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.4 GO:0045095 keratin filament(GO:0045095)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 15.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.3 GO:0001650 fibrillar center(GO:0001650)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 6.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.5 GO:0005770 late endosome(GO:0005770)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 45.5 GO:0005829 cytosol(GO:0005829)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
1.8 7.4 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 3.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.9 4.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.8 3.3 GO:0033797 selenate reductase activity(GO:0033797)
0.8 2.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.8 9.8 GO:0019966 interleukin-1 binding(GO:0019966)
0.6 12.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.6 11.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 3.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 2.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.4 7.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 4.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 5.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 2.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 6.8 GO:0046977 TAP binding(GO:0046977)
0.3 7.0 GO:0044548 S100 protein binding(GO:0044548)
0.3 5.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 2.6 GO:0036122 BMP binding(GO:0036122)
0.2 2.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 9.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 4.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 2.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 5.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 6.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 13.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 2.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 8.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.1 GO:0031386 protein tag(GO:0031386)
0.2 15.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 1.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 7.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 3.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.0 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.7 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 6.0 GO:0005518 collagen binding(GO:0005518)
0.1 2.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.2 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 5.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 5.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 2.0 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 7.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 4.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 18.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 3.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 11.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 7.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 8.3 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 4.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.8 GO:0003924 GTPase activity(GO:0003924)
0.0 6.8 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 10.1 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.9 ST GA12 PATHWAY G alpha 12 Pathway
0.2 6.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 2.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 9.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 7.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 3.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 8.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 19.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 17.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 9.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID INSULIN PATHWAY Insulin Pathway
0.0 2.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 5.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 20.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6 21.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 16.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 8.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 7.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 11.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 5.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 3.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 7.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 10.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 9.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 3.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 2.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 2.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 4.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 4.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 5.3 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 4.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 4.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 2.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation