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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Irx6_Irx2_Irx3

Z-value: 1.07

Motif logo

Transcription factors associated with Irx6_Irx2_Irx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031738.15 Irx6
ENSMUSG00000001504.11 Irx2
ENSMUSG00000031734.14 Irx3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irx2mm39_v1_chr13_+_72776921_727769670.325.9e-03Click!
Irx6mm39_v1_chr8_+_93401454_93401454-0.281.6e-02Click!
Irx3mm39_v1_chr8_-_92528570_925286950.171.5e-01Click!

Activity profile of Irx6_Irx2_Irx3 motif

Sorted Z-values of Irx6_Irx2_Irx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx6_Irx2_Irx3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_44096300 8.53 ENSMUST00000069245.8
serine peptidase inhibitor, Kazal type 5
chr6_-_129449739 6.96 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr8_+_105048856 6.60 ENSMUST00000041973.7
CKLF-like MARVEL transmembrane domain containing 2B
chr6_+_42015319 5.22 ENSMUST00000117406.8
ENSMUST00000024059.5
seminal vesicle antigen
chr5_-_87847268 4.03 ENSMUST00000196869.5
ENSMUST00000199624.5
ENSMUST00000198057.5
ENSMUST00000082370.10
casein beta
chr11_-_97886997 4.02 ENSMUST00000042971.16
ADP-ribosylation factor-like 5C
chr6_-_48685108 3.90 ENSMUST00000126422.3
ENSMUST00000119315.2
ENSMUST00000053661.7
GTPase, IMAP family member 6
chrX_+_106132055 3.79 ENSMUST00000150494.2
purinergic receptor P2Y, G-protein coupled 10
chr4_+_111863441 3.58 ENSMUST00000162885.8
ENSMUST00000117379.9
ENSMUST00000161389.8
ENSMUST00000162158.2
selection and upkeep of intraepithelial T cells 1
chr15_-_76906832 3.11 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr4_+_97665843 3.05 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr3_+_59914164 2.97 ENSMUST00000169794.2
arylacetamide deacetylase like 2
chr3_-_122828592 2.81 ENSMUST00000029761.14
myozenin 2
chr1_+_152626273 2.63 ENSMUST00000068875.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr8_+_85635189 2.53 ENSMUST00000003910.13
ENSMUST00000109744.8
deoxyribonuclease II alpha
chr11_+_14549252 2.43 ENSMUST00000117584.3
POM121 membrane glycoprotein-like 12
chr6_-_130363837 2.39 ENSMUST00000032288.6
killer cell lectin-like receptor, subfamily A, member 1
chr10_+_61007733 2.36 ENSMUST00000122261.8
ENSMUST00000121297.8
ENSMUST00000035894.12
thymus, brain and testes associated
chr16_+_49620883 2.26 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr7_-_24033346 2.17 ENSMUST00000069562.6
tescalcin-like
chr3_-_92627651 2.17 ENSMUST00000047153.4
late cornified envelope 1F
chr8_-_105019806 2.16 ENSMUST00000212492.2
ENSMUST00000034344.10
CKLF-like MARVEL transmembrane domain containing 2A
chr6_+_41039255 2.15 ENSMUST00000103266.3
T cell receptor beta, variable 5
chr17_+_34364206 2.12 ENSMUST00000041982.9
ENSMUST00000171231.8
histocompatibility 2, class II, locus Mb2
chr17_+_30845909 2.08 ENSMUST00000236140.2
ENSMUST00000236118.2
ENSMUST00000235390.2
dynein, axonemal, heavy chain 8
chr14_+_53859114 2.07 ENSMUST00000103657.6
T cell receptor alpha variable 12-3
chr9_-_36549886 2.07 ENSMUST00000093868.9
ENSMUST00000184611.2
prostate and testis expressed 14
chr9_-_44473146 2.05 ENSMUST00000215293.2
chemokine (C-X-C motif) receptor 5
chr6_+_41204430 2.04 ENSMUST00000193064.2
ENSMUST00000103280.3
T cell receptor beta, variable 26
chr14_+_53257873 2.02 ENSMUST00000196756.2
T cell receptor alpha variable 7D-6
chr8_+_72050292 2.02 ENSMUST00000143662.8
niban apoptosis regulator 3
chr1_-_72739704 2.00 ENSMUST00000053499.6
ENSMUST00000212710.2
ENSMUST00000212573.2
ankyrin and armadillo repeat containing
chr8_-_25215778 1.99 ENSMUST00000171438.8
ENSMUST00000171611.9
a disintegrin and metallopeptidase domain 3 (cyritestin)
chrX_+_94601705 1.99 ENSMUST00000210331.2
profilin 5
chr7_-_103477126 1.98 ENSMUST00000023934.8
hemoglobin, beta adult s chain
chr3_+_59832635 1.96 ENSMUST00000049476.3
AADACL2 family member 1
chr1_-_173703424 1.91 ENSMUST00000186442.7
myeloid nuclear differentiation antigen like
chr6_-_130208601 1.91 ENSMUST00000088011.11
ENSMUST00000112013.8
ENSMUST00000049304.14
killer cell lectin-like receptor, subfamily A, member 7
chr14_+_44340111 1.91 ENSMUST00000074839.7
eosinophil-associated, ribonuclease A family, member 2
chr2_+_24235300 1.91 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr8_-_25215856 1.91 ENSMUST00000033958.15
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr13_+_19398273 1.89 ENSMUST00000103558.3
T cell receptor gamma, constant 1
chrX_+_54272236 1.87 ENSMUST00000088740.5
Slx-like 1
chr14_+_53478202 1.86 ENSMUST00000179583.3
T cell receptor alpha variable 12N-3
chr17_+_30843328 1.78 ENSMUST00000170651.2
dynein, axonemal, heavy chain 8
chr14_+_53448363 1.72 ENSMUST00000103618.2
T cell receptor alpha variable 4N-3
chr1_-_72739691 1.72 ENSMUST00000211837.2
ankyrin and armadillo repeat containing
chr10_+_102376109 1.71 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr11_+_11414256 1.69 ENSMUST00000020410.11
spermatogenesis associated 48
chr13_-_35100960 1.68 ENSMUST00000225242.2
family with sequence similarity 217, member A
chr15_+_79775819 1.67 ENSMUST00000177350.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr10_+_111919250 1.67 ENSMUST00000148897.8
ENSMUST00000020434.4
GLI pathogenesis-related 1 like 2
chr14_+_53137426 1.67 ENSMUST00000103592.2
T cell receptor alpha variable 4D-3
chr9_-_99592116 1.64 ENSMUST00000035048.12
claudin 18
chr18_+_44467133 1.64 ENSMUST00000025349.12
ENSMUST00000115498.2
myotilin
chr14_+_53836282 1.63 ENSMUST00000103655.3
T cell receptor alpha variable 4-3
chr14_-_44161016 1.62 ENSMUST00000159175.2
eosinophil-associated, ribonuclease A family, member 10
chr12_-_101784727 1.61 ENSMUST00000222587.2
fibulin 5
chrX_+_53533175 1.59 ENSMUST00000180150.8
predicted gene 16405
chrX_+_53624178 1.59 ENSMUST00000178145.8
predicted gene 16430
chr1_-_159981132 1.57 ENSMUST00000039178.12
tenascin N
chr10_-_125164826 1.57 ENSMUST00000211781.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr16_-_64422716 1.57 ENSMUST00000209382.3
casein kinase 2, alpha prime interacting protein
chr5_-_18054702 1.55 ENSMUST00000165232.8
CD36 molecule
chr8_+_85598734 1.53 ENSMUST00000170296.2
ENSMUST00000136026.8
synaptonemal complex central element protein 2
chr5_-_18054781 1.51 ENSMUST00000170051.8
CD36 molecule
chr6_-_41535322 1.51 ENSMUST00000193003.2
T cell receptor beta, variable 31
chr6_+_41036271 1.50 ENSMUST00000103265.5
T cell receptor beta, variable 10
chr14_+_54068562 1.45 ENSMUST00000103673.11
ENSMUST00000186573.2
T cell receptor alpha variable 18
chr13_+_19528728 1.45 ENSMUST00000179181.3
T cell receptor gamma, constant 4
chr6_-_41535292 1.44 ENSMUST00000103300.3
T cell receptor beta, variable 31
chr14_-_44057096 1.44 ENSMUST00000100691.4
eosinophil-associated, ribonuclease A family, member 1
chr1_-_130557349 1.41 ENSMUST00000142416.2
ENSMUST00000039862.11
ENSMUST00000128128.8
zona pellucida 3 receptor
chr1_+_131566044 1.38 ENSMUST00000073350.13
cathepsin E
chr3_+_106020545 1.37 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr2_-_140231618 1.36 ENSMUST00000122367.8
ENSMUST00000120133.2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr3_+_84573499 1.36 ENSMUST00000107682.2
transmembrane protein 154
chr1_-_28819331 1.32 ENSMUST00000059937.5
predicted gene 597
chr5_-_86893645 1.31 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr12_+_119407145 1.29 ENSMUST00000048880.7
metastasis associated in colon cancer 1
chr8_-_86091970 1.28 ENSMUST00000121972.8
myosin light chain kinase 3
chr8_+_85635341 1.27 ENSMUST00000134569.2
deoxyribonuclease II alpha
chr8_+_13087292 1.27 ENSMUST00000063820.12
ENSMUST00000033821.11
coagulation factor X
chr6_-_130044234 1.26 ENSMUST00000119096.2
killer cell lectin-like receptor, subfamily A, member 4
chr2_+_154032731 1.26 ENSMUST00000081816.11
BPI fold containing family B, member 1
chr6_-_70895899 1.25 ENSMUST00000063456.5
testis expressed 37
chr7_+_44926925 1.25 ENSMUST00000210861.2
solute carrier family 6 member 21
chr6_-_128700022 1.23 ENSMUST00000112110.4
killer cell lectin-like receptor subfamily B member 1
chr4_-_43483696 1.23 ENSMUST00000030180.7
suppression inducing transmembrane adaptor 1
chr1_-_128520002 1.21 ENSMUST00000052172.7
ENSMUST00000142893.2
chemokine (C-X-C motif) receptor 4
chr1_+_45350698 1.20 ENSMUST00000087883.13
collagen, type III, alpha 1
chr8_+_81220410 1.20 ENSMUST00000063359.8
glycophorin A
chr6_-_56878854 1.16 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr6_-_23655130 1.16 ENSMUST00000104979.2
ring finger protein 148
chr6_+_41248311 1.15 ENSMUST00000103281.3
T cell receptor beta, variable 29
chr13_-_21937997 1.15 ENSMUST00000074752.4
H2A clustered histone 15
chr13_-_24945844 1.14 ENSMUST00000006898.10
ENSMUST00000110382.9
geminin
chr2_-_119101680 1.13 ENSMUST00000037360.8
ras homolog family member V
chr6_-_113696390 1.13 ENSMUST00000203588.2
ENSMUST00000204163.3
ENSMUST00000203363.3
ghrelin
chr9_-_35481689 1.13 ENSMUST00000115110.5
HYLS1, centriolar and ciliogenesis associated
chr11_+_88964667 1.12 ENSMUST00000100619.11
predicted gene 525
chr13_-_19495474 1.11 ENSMUST00000197113.2
T cell receptor gamma joining 2
chr7_-_3551003 1.11 ENSMUST00000065703.9
ENSMUST00000203020.3
ENSMUST00000203821.3
T cell-interacting, activating receptor on myeloid cells 1
chr8_-_79539838 1.11 ENSMUST00000146824.2
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr13_+_19394484 1.10 ENSMUST00000200495.2
T cell receptor gamma joining 1
chr6_+_122929627 1.08 ENSMUST00000204427.2
C-type lectin domain family 4, member a3
chrX_-_100307592 1.08 ENSMUST00000101358.3
predicted gene 614
chr10_-_23663109 1.08 ENSMUST00000218221.2
ENSMUST00000218107.2
ribosomal protein S12
chr6_-_116561156 1.08 ENSMUST00000061723.6
olfactory receptor 215
chrX_+_143253677 1.06 ENSMUST00000178233.2
transient receptor potential cation channel, subfamily C, member 5, opposite strand
chrY_-_797405 1.04 ENSMUST00000189888.7
ENSMUST00000065545.6
zinc finger protein 1, Y-linked
chr14_+_53167246 1.03 ENSMUST00000177703.3
T cell receptor alpha variable 12D-3
chr10_+_26105605 1.03 ENSMUST00000218301.2
ENSMUST00000164660.8
ENSMUST00000060716.6
sterile alpha motif domain containing 3
chr3_+_92840279 1.02 ENSMUST00000046234.5
late cornified envelope 3B
chr15_+_91083678 1.02 ENSMUST00000190436.7
cDNA sequence CN725425
chr16_+_35977170 1.02 ENSMUST00000079184.6
stefin A2 like 1
chr19_-_10655391 1.01 ENSMUST00000025647.7
pepsinogen 5, group I
chr7_+_106413336 1.01 ENSMUST00000166880.3
ENSMUST00000075414.8
olfactory receptor 701
chr7_-_130148984 1.01 ENSMUST00000160289.9
NSE4 homolog A, SMC5-SMC6 complex component
chr5_+_77184892 0.99 ENSMUST00000118941.2
theg spermatid protein like
chr3_+_92259448 0.99 ENSMUST00000068399.2
small proline-rich protein 2E
chr7_-_119078472 0.98 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
uromodulin
chr5_+_123214332 0.98 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr14_-_44112974 0.96 ENSMUST00000179200.2
eosinophil-associated, ribonuclease A family, member 1
chr14_-_68893253 0.96 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr10_+_63265871 0.95 ENSMUST00000105441.8
catenin (cadherin associated protein), alpha 3
chr6_+_30512285 0.95 ENSMUST00000031798.14
serine-rich single-pass membrane protein 1
chr10_-_38998272 0.95 ENSMUST00000136546.8
family with sequence similarity 229, member B
chr16_-_19801781 0.94 ENSMUST00000058839.10
kelch-like 6
chrX_-_56326951 0.94 ENSMUST00000114735.9
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr14_+_53562089 0.94 ENSMUST00000178100.3
T cell receptor alpha variable 7N-6
chr6_-_83294526 0.94 ENSMUST00000005810.9
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr1_-_44140820 0.92 ENSMUST00000152239.8
testis expressed 30
chr1_+_190769010 0.92 ENSMUST00000077889.8
spermatogenesis associated 45
chr17_+_41121979 0.92 ENSMUST00000024721.8
ENSMUST00000233740.2
Rhesus blood group-associated A glycoprotein
chr12_-_114728503 0.92 ENSMUST00000194625.2
immunoglobulin heavy variable V1-23
chr13_-_26954110 0.92 ENSMUST00000055915.6
HDGF like 1
chr2_-_17395765 0.91 ENSMUST00000177966.2
nebulette
chr11_-_106205320 0.91 ENSMUST00000167143.2
CD79B antigen
chr6_-_113696809 0.91 ENSMUST00000203770.3
ENSMUST00000064993.8
ghrelin
chr5_-_77359039 0.90 ENSMUST00000121825.2
serine peptidase inhibitor, Kazal type 2
chr1_-_138103021 0.90 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr8_+_85635311 0.90 ENSMUST00000145292.8
deoxyribonuclease II alpha
chr1_-_174078542 0.90 ENSMUST00000061990.5
olfactory receptor 419
chr6_-_136918885 0.90 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_128890092 0.89 ENSMUST00000145798.4
vinculin/alpha-catenin family member 1
chr6_+_41515152 0.88 ENSMUST00000103291.2
ENSMUST00000192856.6
T cell receptor beta, constant region 1
chr8_-_25438784 0.87 ENSMUST00000119720.8
ENSMUST00000121438.9
a disintegrin and metallopeptidase domain 32
chr6_-_136918671 0.87 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr10_+_129691236 0.87 ENSMUST00000204622.3
olfactory receptor 813
chr7_+_28050077 0.86 ENSMUST00000082134.6
ribosomal protein S16
chr3_+_69914946 0.84 ENSMUST00000053013.6
otolin 1
chr4_+_134238310 0.84 ENSMUST00000105866.3
aurora kinase A and ninein interacting protein
chr15_-_74855264 0.84 ENSMUST00000023250.11
ENSMUST00000166694.2
lymphocyte antigen 6 complex, locus I
chr3_-_98471301 0.83 ENSMUST00000058728.10
predicted gene 10681
chr12_-_113666198 0.83 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr11_-_82719850 0.82 ENSMUST00000021036.13
ENSMUST00000074515.11
ENSMUST00000103218.3
ring finger and FYVE like domain containing protein
chr11_-_53508160 0.82 ENSMUST00000150568.8
interleukin 4
chr6_-_142453531 0.82 ENSMUST00000134191.3
ENSMUST00000239397.2
ENSMUST00000239395.2
ENSMUST00000032373.12
lactate dehydrogenase B
chr4_+_57782150 0.82 ENSMUST00000124581.2
paralemmin A kinase anchor protein
chr6_+_41523664 0.81 ENSMUST00000103299.3
T cell receptor beta, constant 2
chr14_+_53941464 0.81 ENSMUST00000103664.6
T cell receptor alpha variable 5-4
chr13_+_4624074 0.81 ENSMUST00000021628.4
aldo-keto reductase family 1, member C21
chr7_-_102566717 0.81 ENSMUST00000214160.2
ENSMUST00000215773.2
olfactory receptor 571
chr5_+_87973541 0.79 ENSMUST00000101056.8
ENSMUST00000002310.8
proline rich 27
chr3_+_92586546 0.79 ENSMUST00000047055.4
late cornified envelope 1C
chr12_-_81468705 0.79 ENSMUST00000085319.4
a disintegrin and metallopeptidase domain 4
chr4_+_98614971 0.79 ENSMUST00000152889.9
ENSMUST00000154279.3
LINE-1 type transposase domain containing 1
chr1_-_138102972 0.79 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr5_-_65248962 0.78 ENSMUST00000212080.2
transmembrane protein 156
chr14_+_67953687 0.78 ENSMUST00000150768.8
potassium channel tetramerisation domain containing 9
chr5_+_110478558 0.77 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr2_+_173364379 0.77 ENSMUST00000029023.4
RIKEN cDNA 1700021F07 gene
chr8_-_57003828 0.77 ENSMUST00000134162.8
ENSMUST00000140107.8
ENSMUST00000040330.15
ENSMUST00000135337.8
centrosomal protein 44
chr6_+_41192984 0.76 ENSMUST00000193997.6
ENSMUST00000103279.3
T cell receptor beta, variable V23
chrY_+_52778041 0.76 ENSMUST00000178673.2
predicted gene, 21258
chr11_-_118021460 0.76 ENSMUST00000132685.9
dynein, axonemal, heavy chain 17
chr2_+_101508747 0.76 ENSMUST00000004949.8
TNF receptor-associated factor 6
chr3_+_104974160 0.75 ENSMUST00000070584.5
RIKEN cDNA 4930564D02 gene
chr4_-_117035922 0.75 ENSMUST00000153953.2
ENSMUST00000106436.8
kinesin family member 2C
chr9_+_64080644 0.75 ENSMUST00000034966.9
ribosomal protein L4
chrY_-_68304748 0.74 ENSMUST00000180329.2
predicted gene, 20937
chr1_+_61017057 0.74 ENSMUST00000027162.12
ENSMUST00000102827.4
inducible T cell co-stimulator
chr12_-_113860566 0.74 ENSMUST00000103474.5
immunoglobulin heavy variable 7-1
chr4_-_73869071 0.73 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr4_-_112632013 0.73 ENSMUST00000060327.4
selection and upkeep of intraepithelial T cells 10
chr16_-_19525122 0.73 ENSMUST00000081880.7
lysosomal-associated membrane protein 3
chr6_-_54949587 0.73 ENSMUST00000060655.15
nucleotide-binding oligomerization domain containing 1
chr10_+_84412490 0.73 ENSMUST00000020223.8
t-complex 11 (mouse) like 2
chr17_+_87224776 0.73 ENSMUST00000042172.7
transmembrane protein 247
chr6_-_124704237 0.72 ENSMUST00000174787.2
ENSMUST00000172690.2
protein tyrosine phosphatase, non-receptor type 6
chrY_+_77705501 0.72 ENSMUST00000179073.2
predicted gene, 21650
chrY_-_72256967 0.72 ENSMUST00000178505.2
predicted gene, 20843
chr6_-_136918844 0.72 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_43156329 0.72 ENSMUST00000228117.2
predicted gene 9732
chr2_-_88058678 0.72 ENSMUST00000214386.2
olfactory receptor 1170
chr9_-_64080161 0.71 ENSMUST00000176299.8
ENSMUST00000130127.8
ENSMUST00000176794.8
ENSMUST00000177045.8
zwilch kinetochore protein
chrY_+_80146479 0.71 ENSMUST00000179811.2
predicted gene, 21760
chr11_+_48728291 0.71 ENSMUST00000046903.6
tripartite motif-containing 7
chr2_+_24181208 0.71 ENSMUST00000058056.2
interleukin 1 family, member 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.5 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
1.0 4.0 GO:1903487 regulation of lactation(GO:1903487)
0.6 3.1 GO:0070543 response to linoleic acid(GO:0070543)
0.5 2.1 GO:1904346 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.4 2.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 1.7 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.4 1.7 GO:0072023 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.4 2.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.4 1.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.4 1.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 3.2 GO:0015671 oxygen transport(GO:0015671)
0.4 2.2 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.3 3.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.3 3.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.3 2.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 0.8 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.3 0.8 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 5.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.2 0.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 1.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.2 0.6 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.3 GO:0008228 opsonization(GO:0008228)
0.2 4.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 1.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.2 0.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.2 0.5 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 3.0 GO:0072189 ureter development(GO:0072189)
0.1 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 3.0 GO:0032196 transposition(GO:0032196)
0.1 7.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.7 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 0.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.6 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.3 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.3 GO:0002227 innate immune response in mucosa(GO:0002227) negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 1.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.3 GO:0010924 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.1 1.5 GO:0015747 urate transport(GO:0015747)
0.1 3.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.7 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 6.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.7 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.2 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.1 0.8 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 1.1 GO:1902572 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.5 GO:0021815 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 0.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 1.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 1.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.7 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.0 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 2.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.5 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 15.7 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.6 GO:0015884 folic acid transport(GO:0015884)
0.0 0.9 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.6 GO:0003341 cilium movement(GO:0003341)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.3 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 1.5 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.7 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.3 GO:0006026 aminoglycan catabolic process(GO:0006026)
0.0 0.7 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 23.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 2.6 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 2.4 GO:0048515 spermatid differentiation(GO:0048515)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 4.6 GO:0036157 outer dynein arm(GO:0036157)
0.4 2.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.4 GO:0043159 acrosomal matrix(GO:0043159)
0.3 1.6 GO:0071953 elastic fiber(GO:0071953)
0.3 3.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.7 GO:1990423 RZZ complex(GO:1990423)
0.2 0.7 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.2 0.7 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.2 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.5 GO:0000801 central element(GO:0000801)
0.2 0.5 GO:0000811 GINS complex(GO:0000811)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 18.4 GO:0000800 lateral element(GO:0000800)
0.1 7.0 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0097635 extrinsic component of pre-autophagosomal structure membrane(GO:0097632) extrinsic component of autophagosome membrane(GO:0097635)
0.1 1.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 1.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.9 GO:0019815 B cell receptor complex(GO:0019815)
0.1 2.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.1 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.0 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 3.3 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 3.8 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.7 2.0 GO:0031768 ghrelin receptor binding(GO:0031768)
0.6 3.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 2.8 GO:0051373 FATZ binding(GO:0051373)
0.5 2.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.5 1.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 3.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 2.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 0.7 GO:0019767 IgE receptor activity(GO:0019767)
0.3 1.0 GO:0045142 triplex DNA binding(GO:0045142)
0.3 1.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 3.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 0.8 GO:0070401 NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.3 2.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 0.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 1.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 3.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 0.9 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 0.6 GO:0019809 spermidine binding(GO:0019809)
0.2 5.4 GO:0045503 dynein light chain binding(GO:0045503)
0.2 0.5 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 1.7 GO:0019864 IgG binding(GO:0019864)
0.1 1.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.6 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.2 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.1 2.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.6 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.8 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 7.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 4.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 4.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 5.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 1.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 22.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 8.0 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 1.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 3.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 3.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 3.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases