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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Jun

Z-value: 1.30

Motif logo

Transcription factors associated with Jun

Gene Symbol Gene ID Gene Info
ENSMUSG00000052684.5 Jun

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Junmm39_v1_chr4_-_94940425_949404590.515.2e-06Click!

Activity profile of Jun motif

Sorted Z-values of Jun motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Jun

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_92393193 13.51 ENSMUST00000054599.8
small proline-rich protein 1A
chr10_+_18720760 12.24 ENSMUST00000019998.9
PERP, TP53 apoptosis effector
chr6_-_87327885 11.05 ENSMUST00000032129.3
gastrokine 1
chr7_+_30487322 11.04 ENSMUST00000189673.7
ENSMUST00000190990.7
ENSMUST00000189962.7
ENSMUST00000187493.7
ENSMUST00000098559.3
keratinocyte differentiation associated protein
chr15_-_74618533 10.94 ENSMUST00000057932.8
secreted Ly6/Plaur domain containing 2
chr5_+_36361360 10.89 ENSMUST00000052224.6
prosaposin-like 1
chr4_+_128999325 10.61 ENSMUST00000106064.10
ENSMUST00000030575.15
ENSMUST00000030577.11
transmembrane protein 54
chr7_+_140918793 9.46 ENSMUST00000026577.13
EPS8-like 2
chr19_+_8966641 9.33 ENSMUST00000092956.4
ENSMUST00000092955.11
AHNAK nucleoprotein (desmoyokin)
chr17_-_31383976 8.81 ENSMUST00000235870.2
trefoil factor 1
chr11_+_76795346 8.77 ENSMUST00000072633.4
transmembrane and immunoglobulin domain containing 1
chr7_+_30463175 8.65 ENSMUST00000165887.8
ENSMUST00000085691.11
ENSMUST00000054427.13
ENSMUST00000085688.11
dermokine
chr7_+_18817767 8.56 ENSMUST00000032568.14
ENSMUST00000122999.8
ENSMUST00000108473.10
ENSMUST00000108474.2
ENSMUST00000238982.2
dystrophia myotonica-protein kinase
chr18_+_12637217 8.46 ENSMUST00000188815.2
laminin, alpha 3
chr4_+_43506966 8.45 ENSMUST00000030183.10
carbonic anhydrase 9
chr15_-_74599860 8.37 ENSMUST00000023261.4
ENSMUST00000190433.2
secreted Ly6/Plaur domain containing 1
chr5_-_134975773 8.16 ENSMUST00000051401.4
claudin 4
chr7_+_140918876 7.99 ENSMUST00000143633.4
EPS8-like 2
chr4_+_118384426 7.77 ENSMUST00000030261.6
RIKEN cDNA 2610528J11 gene
chr2_+_151414524 7.69 ENSMUST00000028950.9
syndecan binding protein (syntenin) 2
chr2_-_25129863 7.61 ENSMUST00000186719.2
ENSMUST00000043379.5
cysteine rich tail 1
chr17_-_25973288 7.58 ENSMUST00000075884.8
ENSMUST00000238120.2
ENSMUST00000236137.2
ENSMUST00000237359.2
mesothelin
chr11_-_100139728 7.56 ENSMUST00000007280.9
keratin 16
chr7_+_30475819 7.53 ENSMUST00000041703.10
dermokine
chr4_-_133329479 7.52 ENSMUST00000057311.4
stratifin
chr7_+_28563255 7.50 ENSMUST00000138272.8
lectin, galactose binding, soluble 7
chr7_+_140659038 7.42 ENSMUST00000159375.8
plakophilin 3
chr14_+_102078038 7.32 ENSMUST00000159314.8
LIM domain only 7
chr19_-_32080496 7.21 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr2_+_69210775 7.21 ENSMUST00000063690.4
dehydrogenase/reductase (SDR family) member 9
chr11_+_9068098 7.12 ENSMUST00000020677.8
ENSMUST00000101525.9
uridine phosphorylase 1
chr7_-_44320244 7.11 ENSMUST00000048102.15
myosin, heavy polypeptide 14
chr17_+_87944110 6.73 ENSMUST00000234623.2
epithelial cell adhesion molecule
chr3_+_93427791 6.72 ENSMUST00000029515.5
S100 calcium binding protein A11
chr16_-_56652241 6.72 ENSMUST00000135672.2
transmembrane protein 45a
chr5_-_76511634 6.71 ENSMUST00000031146.3
neuromedin U
chr11_+_76795292 6.71 ENSMUST00000142166.8
transmembrane and immunoglobulin domain containing 1
chr8_-_110765983 6.68 ENSMUST00000109222.4
carbohydrate sulfotransferase 4
chr3_+_137923521 6.66 ENSMUST00000090171.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_172328768 6.34 ENSMUST00000111228.2
transgelin 2
chr6_+_49013517 6.17 ENSMUST00000031840.10
glycoprotein (transmembrane) nmb
chr1_+_182392577 6.06 ENSMUST00000048941.14
calpain 8
chr2_+_155593030 6.02 ENSMUST00000029140.12
ENSMUST00000132608.2
protein C receptor, endothelial
chr4_+_118384183 6.00 ENSMUST00000106367.8
RIKEN cDNA 2610528J11 gene
chr6_+_49013601 5.96 ENSMUST00000204260.2
glycoprotein (transmembrane) nmb
chr2_+_143757193 5.91 ENSMUST00000103172.4
destrin
chr11_+_9068134 5.90 ENSMUST00000170444.8
uridine phosphorylase 1
chr12_+_75355082 5.65 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr6_-_113411718 5.57 ENSMUST00000113091.8
cell death-inducing DFFA-like effector c
chr3_+_92315290 5.50 ENSMUST00000047264.3
small proline-rich protein 2I
chr1_+_182392559 5.49 ENSMUST00000168514.7
calpain 8
chr12_-_103423472 5.45 ENSMUST00000044687.7
interferon, alpha-inducible protein 27 like 2B
chr3_+_14706781 5.41 ENSMUST00000029071.9
carbonic anhydrase 13
chr8_-_62044164 5.34 ENSMUST00000135439.2
ENSMUST00000121200.9
palladin, cytoskeletal associated protein
chr14_+_102077937 5.32 ENSMUST00000159026.8
LIM domain only 7
chrX_+_72719098 5.26 ENSMUST00000171398.2
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_-_28947882 5.23 ENSMUST00000032808.6
RIKEN cDNA 2200002D01 gene
chr7_+_24335969 5.21 ENSMUST00000080718.6
Ly6/Plaur domain containing 3
chr7_-_105131407 5.17 ENSMUST00000047040.4
caveolae associated 3
chr10_-_76562002 5.13 ENSMUST00000001147.5
collagen, type VI, alpha 1
chr3_-_88410495 5.02 ENSMUST00000120377.8
ENSMUST00000029699.13
lamin A
chr12_+_31315270 4.98 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chr3_-_95158457 4.93 ENSMUST00000125515.3
ENSMUST00000107195.9
BCL2/adenovirus E1B 19kD interacting protein like
chrX_-_7537580 4.90 ENSMUST00000033486.6
proteolipid protein 2
chr19_-_11796282 4.90 ENSMUST00000069285.6
syntaxin 3
chr3_-_95646856 4.89 ENSMUST00000153026.8
ENSMUST00000123143.8
ENSMUST00000137912.8
ENSMUST00000029753.14
ENSMUST00000131376.8
ENSMUST00000117507.10
ENSMUST00000128885.8
ENSMUST00000147217.2
extracellular matrix protein 1
chr3_-_59102517 4.89 ENSMUST00000200095.2
G protein-coupled receptor 87
chr10_-_43880353 4.88 ENSMUST00000020017.14
crystallin beta-gamma domain containing 1
chr13_+_75987987 4.82 ENSMUST00000022082.8
ENSMUST00000223120.2
ENSMUST00000220523.2
glutaredoxin
chr11_-_69771797 4.77 ENSMUST00000238978.2
potassium channel tetramerisation domain containing 11
chr7_+_127728712 4.65 ENSMUST00000033053.8
ENSMUST00000205460.2
integrin alpha X
chr5_+_32293145 4.65 ENSMUST00000031017.11
fos-like antigen 2
chr8_-_110766009 4.65 ENSMUST00000212934.2
carbohydrate sulfotransferase 4
chr3_-_95158360 4.65 ENSMUST00000098871.11
ENSMUST00000137250.9
BCL2/adenovirus E1B 19kD interacting protein like
chr19_+_8975249 4.61 ENSMUST00000236390.2
AHNAK nucleoprotein (desmoyokin)
chr7_+_30450896 4.60 ENSMUST00000182229.8
ENSMUST00000080518.14
ENSMUST00000182227.8
ENSMUST00000182721.8
suprabasin
chr6_+_30568366 4.60 ENSMUST00000049251.6
carboxypeptidase A4
chr7_+_141988714 4.52 ENSMUST00000118276.8
ENSMUST00000105976.8
ENSMUST00000097939.9
synaptotagmin VIII
chr3_-_92481033 4.50 ENSMUST00000053107.6
involucrin
chr7_-_4607040 4.44 ENSMUST00000166650.3
protein tyrosine phosphatase, receptor type, H
chr12_+_31315227 4.43 ENSMUST00000169088.8
laminin B1
chr7_+_141048722 4.43 ENSMUST00000058746.7
CD151 antigen
chr8_-_62576140 4.34 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr2_+_24226857 4.32 ENSMUST00000114487.9
ENSMUST00000142093.7
interleukin 1 receptor antagonist
chr5_+_93004330 4.31 ENSMUST00000225438.2
shroom family member 3
chr17_-_24863956 4.25 ENSMUST00000019684.13
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_+_18573879 4.22 ENSMUST00000072415.9
ENSMUST00000072386.11
ENSMUST00000228493.2
ENSMUST00000227379.2
MHC I like leukocyte 2
chr9_+_44953723 4.18 ENSMUST00000034600.5
myelin protein zero-like 2
chr7_-_140856642 4.14 ENSMUST00000080654.7
ENSMUST00000167263.9
cadherin-related family member 5
chr2_+_103242027 4.08 ENSMUST00000239273.2
ENSMUST00000164172.8
E74-like factor 5
chr3_+_142326363 4.06 ENSMUST00000165774.8
guanylate binding protein 2
chr17_+_35268942 4.02 ENSMUST00000007257.10
chloride intracellular channel 1
chr11_+_61575245 3.99 ENSMUST00000093019.6
family with sequence similarity 83, member G
chr14_-_70415117 3.98 ENSMUST00000022681.11
PDZ and LIM domain 2
chr7_+_126365506 3.97 ENSMUST00000032944.9
glycerophosphodiester phosphodiesterase domain containing 3
chr18_-_38131766 3.91 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr14_+_14210394 3.76 ENSMUST00000164598.8
acyl-Coenzyme A oxidase 2, branched chain
chr14_-_34310602 3.69 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr1_+_107517726 3.68 ENSMUST00000000514.11
ENSMUST00000112706.4
serine (or cysteine) peptidase inhibitor, clade B, member 8
chr13_-_95754987 3.66 ENSMUST00000059193.7
coagulation factor II (thrombin) receptor
chr16_+_17379749 3.62 ENSMUST00000171002.10
ENSMUST00000023441.11
purinergic receptor P2X, ligand-gated ion channel, 6
chr5_-_66238313 3.59 ENSMUST00000202700.4
ENSMUST00000094757.9
ENSMUST00000113724.6
RNA binding motif protein 47
chr7_+_30252687 3.57 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr14_+_14210932 3.51 ENSMUST00000022271.14
acyl-Coenzyme A oxidase 2, branched chain
chr6_+_17463925 3.50 ENSMUST00000115442.8
met proto-oncogene
chr7_-_80051455 3.42 ENSMUST00000120753.3
furin (paired basic amino acid cleaving enzyme)
chr7_-_144305705 3.40 ENSMUST00000155175.8
anoctamin 1, calcium activated chloride channel
chr9_-_116004386 3.37 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr1_+_171265103 3.35 ENSMUST00000043839.5
F11 receptor
chr9_+_7445822 3.35 ENSMUST00000034497.8
matrix metallopeptidase 3
chr2_+_110551927 3.33 ENSMUST00000111017.9
mucin 15
chr18_+_42186713 3.32 ENSMUST00000072008.11
SH3 domain containing ring finger 2
chr7_-_143056252 3.30 ENSMUST00000010904.5
pleckstrin homology like domain, family A, member 2
chr17_-_24863907 3.29 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr8_+_72889073 3.23 ENSMUST00000003575.11
tropomyosin 4
chr3_-_88243455 3.23 ENSMUST00000193872.2
transmembrane protein 79
chr1_-_190915441 3.18 ENSMUST00000027941.14
activating transcription factor 3
chr10_+_12966532 3.16 ENSMUST00000121646.8
ENSMUST00000121325.8
ENSMUST00000121766.8
pleiomorphic adenoma gene-like 1
chr16_+_33614715 3.15 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr9_-_116004265 3.14 ENSMUST00000061101.12
transforming growth factor, beta receptor II
chr17_+_44263890 3.09 ENSMUST00000177857.9
ENSMUST00000044792.6
regulator of calcineurin 2
chr8_-_25581354 3.08 ENSMUST00000125466.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr3_+_27371168 3.07 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr2_+_174602412 3.02 ENSMUST00000029030.9
endothelin 3
chr7_-_45391879 2.99 ENSMUST00000210754.2
ENSMUST00000210147.2
sulfotransferase family, cytosolic, 2B, member 1
chr6_+_17463748 2.96 ENSMUST00000115443.8
met proto-oncogene
chr18_+_42186757 2.95 ENSMUST00000074679.4
SH3 domain containing ring finger 2
chr2_+_70948267 2.95 ENSMUST00000028403.3
cytochrome b reductase 1
chr2_+_110551685 2.94 ENSMUST00000111016.9
mucin 15
chr19_-_4092218 2.93 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chrX_-_7606445 2.90 ENSMUST00000128289.8
coiled-coil domain containing 120
chr6_-_113411489 2.88 ENSMUST00000133348.2
cell death-inducing DFFA-like effector c
chr1_+_74164700 2.88 ENSMUST00000080167.11
ENSMUST00000127134.2
RUN and FYVE domain containing 4
chr2_+_84891281 2.85 ENSMUST00000238769.2
tankyrase 1 binding protein 1
chr2_-_17735847 2.85 ENSMUST00000028080.12
nebulette
chr8_+_21868531 2.85 ENSMUST00000170275.4
defensin, alpha, 2
chr3_+_87855973 2.81 ENSMUST00000005019.6
cellular retinoic acid binding protein II
chr14_-_34310438 2.81 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr2_+_110551976 2.79 ENSMUST00000090332.5
mucin 15
chr2_+_160722562 2.78 ENSMUST00000109456.9
lipin 3
chr10_+_94386714 2.77 ENSMUST00000148910.3
ENSMUST00000117460.8
transmembrane and coiled coil domains 3
chr3_+_27371206 2.76 ENSMUST00000174840.2
tumor necrosis factor (ligand) superfamily, member 10
chr2_+_25285878 2.76 ENSMUST00000028328.3
ectonucleoside triphosphate diphosphohydrolase 2
chr9_-_75448979 2.74 ENSMUST00000214171.2
tropomodulin 3
chr4_-_45489794 2.73 ENSMUST00000146236.8
src homology 2 domain-containing transforming protein B
chr6_+_17463819 2.67 ENSMUST00000140070.8
met proto-oncogene
chr11_-_69906171 2.65 ENSMUST00000018718.8
ENSMUST00000102574.10
acyl-Coenzyme A dehydrogenase, very long chain
chr3_-_92346078 2.52 ENSMUST00000062160.4
small proline-rich protein 1B
chr7_-_100613579 2.47 ENSMUST00000060174.6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_132809189 2.46 ENSMUST00000113304.2
sushi-repeat-containing protein, X-linked 2
chr14_-_52011035 2.46 ENSMUST00000073860.6
angiogenin, ribonuclease A family, member 4
chr6_-_122833109 2.46 ENSMUST00000042081.9
complement component 3a receptor 1
chr1_-_37575313 2.43 ENSMUST00000042161.15
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chrX_-_165992145 2.38 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chrX_+_132809166 2.37 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr8_-_78244412 2.34 ENSMUST00000210922.2
ENSMUST00000210519.2
Rho GTPase activating protein 10
chrX_+_163052367 2.32 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr2_+_145627900 2.28 ENSMUST00000110005.8
ENSMUST00000094480.11
Ras and Rab interactor 2
chr1_+_180978491 2.21 ENSMUST00000134115.8
ENSMUST00000111059.2
cornichon family AMPA receptor auxiliary protein 4
chr15_-_75886166 2.20 ENSMUST00000060807.12
family with sequence similarity 83, member H
chr3_-_122828592 2.20 ENSMUST00000029761.14
myozenin 2
chr10_+_128769642 2.19 ENSMUST00000099112.4
ENSMUST00000218290.2
integrin alpha 7
chr3_-_131196213 2.18 ENSMUST00000197057.2
sphingomyelin synthase 2
chr19_-_4087940 2.17 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr11_+_76836545 2.16 ENSMUST00000125145.8
bleomycin hydrolase
chr7_-_19005721 2.16 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr13_-_24175141 2.15 ENSMUST00000021770.8
secretagogin, EF-hand calcium binding protein
chr15_-_102165740 2.13 ENSMUST00000135466.2
retinoic acid receptor, gamma
chrX_-_73067351 2.11 ENSMUST00000114353.10
ENSMUST00000101458.9
interleukin-1 receptor-associated kinase 1
chr16_+_33575920 2.06 ENSMUST00000128105.2
heart development protein with EGF-like domains 1
chr9_+_7347369 2.04 ENSMUST00000005950.12
ENSMUST00000065079.6
matrix metallopeptidase 12
chr9_+_7272514 2.02 ENSMUST00000015394.10
matrix metallopeptidase 13
chr14_-_55995912 2.02 ENSMUST00000001497.9
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chrX_-_73067514 2.00 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
interleukin-1 receptor-associated kinase 1
chr9_-_86577940 2.00 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_+_43418321 1.97 ENSMUST00000107970.8
kallikrein related-peptidase 12
chr19_-_4087907 1.95 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr5_-_86780277 1.94 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr18_+_61178211 1.92 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr19_-_11796085 1.91 ENSMUST00000211047.2
ENSMUST00000075304.14
ENSMUST00000211641.2
syntaxin 3
chr19_+_29229147 1.91 ENSMUST00000025705.7
ENSMUST00000065796.10
ENSMUST00000236990.2
Janus kinase 2
chr6_+_48849804 1.90 ENSMUST00000204856.2
amine oxidase, copper-containing 1
chr9_+_78522783 1.90 ENSMUST00000093812.5
CD109 antigen
chr7_+_4463686 1.88 ENSMUST00000167298.2
ENSMUST00000171445.8
EPS8-like 1
chr3_+_79793237 1.85 ENSMUST00000029567.9
golgi associated kinase 1B
chr2_-_113883285 1.85 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr6_-_115735935 1.84 ENSMUST00000072933.13
transmembrane protein 40
chr11_-_83957889 1.83 ENSMUST00000108101.8
dual specificity phosphatase 14
chr11_+_73158214 1.79 ENSMUST00000049676.3
transient receptor potential cation channel, subfamily V, member 3
chr18_-_35760260 1.77 ENSMUST00000025212.8
solute carrier family 23 (nucleobase transporters), member 1
chr2_+_162829250 1.77 ENSMUST00000018012.14
serum/glucocorticoid regulated kinase 2
chr16_+_58548273 1.74 ENSMUST00000023426.12
ENSMUST00000162057.8
ENSMUST00000162191.2
claudin domain containing 1
chr9_-_106353571 1.73 ENSMUST00000123555.8
ENSMUST00000125850.2
poly (ADP-ribose) polymerase family, member 3
chr14_-_56499690 1.72 ENSMUST00000015581.6
granzyme B
chr16_-_30102070 1.71 ENSMUST00000064606.8
leucine rich repeat containing 15
chr7_-_133384449 1.71 ENSMUST00000063669.8
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr9_+_106247943 1.71 ENSMUST00000173748.2
dual specificity phosphatase 7
chr15_-_74650673 1.69 ENSMUST00000186014.2
ENSMUST00000191407.2
lymphocyte antigen 6 complex, locus G6G
chr1_+_170104889 1.68 ENSMUST00000179976.3
SH2 domain containing 1B1
chr11_+_76836330 1.64 ENSMUST00000021197.10
bleomycin hydrolase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
4.0 16.2 GO:1903575 cornified envelope assembly(GO:1903575)
3.8 11.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
2.5 7.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
2.4 9.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
2.2 6.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.8 5.3 GO:0015881 creatine transport(GO:0015881)
1.7 8.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.7 6.7 GO:0006069 ethanol oxidation(GO:0006069)
1.4 7.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.4 4.1 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
1.3 19.7 GO:0002934 desmosome organization(GO:0002934)
1.3 9.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.3 20.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
1.3 5.2 GO:1901003 negative regulation of fermentation(GO:1901003)
1.2 3.7 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.2 7.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.0 5.9 GO:0030043 actin filament fragmentation(GO:0030043)
1.0 2.9 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.9 3.8 GO:0043418 homocysteine catabolic process(GO:0043418)
0.9 18.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.9 8.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.9 9.6 GO:0040009 regulation of growth rate(GO:0040009)
0.9 3.4 GO:0090472 dibasic protein processing(GO:0090472)
0.8 5.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 4.1 GO:1904970 brush border assembly(GO:1904970)
0.8 4.8 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.8 3.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.8 10.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.7 4.4 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.7 2.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.7 4.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.7 21.5 GO:0031424 keratinization(GO:0031424)
0.7 6.8 GO:0016081 synaptic vesicle docking(GO:0016081)
0.6 1.9 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.6 3.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 1.9 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.6 1.9 GO:0097185 amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.6 1.8 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.6 4.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.6 8.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 4.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.5 3.2 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.5 2.1 GO:0003017 lymph circulation(GO:0003017)
0.5 4.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.5 2.0 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.5 10.0 GO:0003334 keratinocyte development(GO:0003334)
0.4 5.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 3.9 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 4.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.4 1.3 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.4 3.0 GO:0000103 sulfate assimilation(GO:0000103)
0.4 1.7 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.4 10.9 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.4 2.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 6.7 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.4 14.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 1.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 3.2 GO:0006108 malate metabolic process(GO:0006108)
0.4 2.5 GO:0002461 complement receptor mediated signaling pathway(GO:0002430) tolerance induction dependent upon immune response(GO:0002461) positive regulation of glomerular mesangial cell proliferation(GO:0072126)
0.3 4.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 1.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 8.4 GO:0034389 lipid particle organization(GO:0034389)
0.3 3.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 10.9 GO:0043616 keratinocyte proliferation(GO:0043616)
0.3 0.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 3.4 GO:0015705 iodide transport(GO:0015705)
0.3 2.8 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.3 0.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 4.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 1.7 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.3 3.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 0.5 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 2.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 1.3 GO:0052041 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.3 1.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 2.0 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 2.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.3 1.8 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.3 7.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 2.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 13.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 3.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 0.7 GO:0036145 dendritic cell homeostasis(GO:0036145)
0.2 1.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.2 GO:1905161 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2 2.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 3.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) spongiotrophoblast differentiation(GO:0060708) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 2.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.8 GO:0009838 abscission(GO:0009838)
0.2 4.1 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.2 7.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 5.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 1.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.2 1.4 GO:2000286 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 10.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 5.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 1.6 GO:0072602 interleukin-4 secretion(GO:0072602)
0.2 0.8 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2 3.3 GO:1900120 regulation of receptor binding(GO:1900120)
0.1 4.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 1.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 21.8 GO:0007586 digestion(GO:0007586)
0.1 1.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 2.9 GO:0010039 response to iron ion(GO:0010039)
0.1 11.1 GO:0030239 myofibril assembly(GO:0030239)
0.1 1.0 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.9 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.6 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 3.6 GO:0033198 response to ATP(GO:0033198)
0.1 5.4 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 7.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.8 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 1.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 5.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.8 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 3.7 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.1 4.2 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.6 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 1.1 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 3.5 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 2.1 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 3.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 10.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 3.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 5.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 3.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 3.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.9 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 2.7 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 8.6 GO:0008544 epidermis development(GO:0008544)
0.0 4.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 3.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 4.0 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.0 2.2 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0002716 negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 1.3 GO:0016202 regulation of striated muscle tissue development(GO:0016202)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0005607 laminin-2 complex(GO:0005607)
2.1 8.5 GO:0005608 laminin-3 complex(GO:0005608)
1.5 7.4 GO:0005914 spot adherens junction(GO:0005914)
1.4 7.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
1.0 7.1 GO:0097513 myosin II filament(GO:0097513)
0.7 2.2 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.7 5.0 GO:0005638 lamin filament(GO:0005638)
0.6 1.8 GO:0042643 actomyosin, actin portion(GO:0042643)
0.6 3.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.6 11.0 GO:0042599 lamellar body(GO:0042599)
0.5 26.0 GO:0001533 cornified envelope(GO:0001533)
0.5 1.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.4 1.7 GO:0044194 cytolytic granule(GO:0044194)
0.4 4.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3 3.7 GO:0031094 platelet dense tubular network(GO:0031094)
0.3 0.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 4.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.3 8.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 2.9 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 7.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 3.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 3.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 3.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 3.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 1.3 GO:0005827 polar microtubule(GO:0005827)
0.2 4.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.9 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 2.8 GO:0005605 basal lamina(GO:0005605)
0.1 1.7 GO:0031209 SCAR complex(GO:0031209)
0.1 2.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.6 GO:0008305 integrin complex(GO:0008305)
0.1 15.2 GO:0030315 T-tubule(GO:0030315)
0.1 11.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 13.5 GO:0005811 lipid particle(GO:0005811)
0.1 21.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 6.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 17.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.1 7.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 7.5 GO:0032420 stereocilium(GO:0032420)
0.1 1.0 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.2 GO:0031143 pseudopodium(GO:0031143)
0.1 10.9 GO:0005901 caveola(GO:0005901)
0.1 3.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 7.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 4.3 GO:0005902 microvillus(GO:0005902)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 7.3 GO:0005581 collagen trimer(GO:0005581)
0.1 6.0 GO:0005882 intermediate filament(GO:0005882)
0.1 4.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 4.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.4 GO:0005604 basement membrane(GO:0005604)
0.0 5.8 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0090543 Flemming body(GO:0090543)
0.0 6.7 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 2.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 8.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 11.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 73.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 5.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 60.4 GO:0005576 extracellular region(GO:0005576)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 15.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
2.3 13.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
2.3 9.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
2.3 13.5 GO:0030280 structural constituent of epidermis(GO:0030280)
2.2 6.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
2.2 13.0 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.8 5.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
1.6 11.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.6 4.8 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
1.2 12.1 GO:0045545 syndecan binding(GO:0045545)
1.2 8.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.1 4.4 GO:0031708 endothelin B receptor binding(GO:0031708)
1.1 4.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.0 9.4 GO:0043208 glycosphingolipid binding(GO:0043208)
1.0 4.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.9 3.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.9 7.2 GO:0017040 ceramidase activity(GO:0017040)
0.9 2.7 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.8 11.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 2.3 GO:0008127 quercetin 2,3-dioxygenase activity(GO:0008127)
0.8 13.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 14.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.7 2.0 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.6 16.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 1.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.6 1.9 GO:0052597 diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.6 2.5 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.6 7.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.6 1.8 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.6 3.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.5 3.2 GO:1990254 keratin filament binding(GO:1990254)
0.5 19.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 3.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 2.2 GO:0051373 FATZ binding(GO:0051373)
0.4 3.0 GO:0050294 alcohol sulfotransferase activity(GO:0004027) steroid sulfotransferase activity(GO:0050294)
0.4 13.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 2.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.4 3.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 1.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.4 6.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.4 5.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 2.9 GO:0051425 PTB domain binding(GO:0051425)
0.4 1.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.3 4.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 4.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 1.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 3.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 2.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.3 4.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 12.2 GO:0043236 laminin binding(GO:0043236)
0.3 7.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 2.5 GO:0004875 complement receptor activity(GO:0004875)
0.3 3.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 11.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 12.6 GO:0042805 actinin binding(GO:0042805)
0.2 3.7 GO:0005522 profilin binding(GO:0005522)
0.2 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 3.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 3.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 4.9 GO:0019956 chemokine binding(GO:0019956)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 3.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.4 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 2.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 5.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 10.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 5.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 7.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 1.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.9 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 16.1 GO:0008083 growth factor activity(GO:0008083)
0.1 1.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 4.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 5.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 12.8 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 3.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 4.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 7.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 4.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.5 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 6.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 5.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.7 GO:0004519 endonuclease activity(GO:0004519)
0.0 7.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 24.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 13.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 7.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 6.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 15.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 6.3 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 4.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 24.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 6.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 10.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 4.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 5.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 9.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 6.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 12.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 9.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 17.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 5.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 6.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 3.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 8.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 3.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 6.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 15.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 2.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 7.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 4.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 3.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 3.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 12.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 5.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 6.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.0 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction