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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Klf3

Z-value: 0.43

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Transcription factors associated with Klf3

Gene Symbol Gene ID Gene Info
Klf3
ENSMUSG00000029178.15 Klf3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf3mm39_v1_chr5_+_64960705_64960731-0.132.7e-01Click!

Activity profile of Klf3 motif

Sorted Z-values of Klf3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_82933383 3.53 ENSMUST00000029630.15
ENSMUST00000166581.4
Fga
fibrinogen alpha chain
chr9_-_50657800 2.72 ENSMUST00000239417.2
ENSMUST00000034564.4
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr13_+_89687915 1.88 ENSMUST00000022108.9
Hapln1
hyaluronan and proteoglycan link protein 1
chr2_+_163389068 1.85 ENSMUST00000109411.8
ENSMUST00000018094.13
Hnf4a
hepatic nuclear factor 4, alpha
chr19_+_10018914 1.04 ENSMUST00000115995.4
Fads3
fatty acid desaturase 3
chr7_-_140676596 0.90 ENSMUST00000209199.2
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr11_+_68858942 0.86 ENSMUST00000102606.10
ENSMUST00000018884.6
Slc25a35
solute carrier family 25, member 35
chr3_-_108306267 0.84 ENSMUST00000147251.2
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr9_-_108183356 0.84 ENSMUST00000192886.6
Tcta
T cell leukemia translocation altered gene
chr17_-_23941757 0.84 ENSMUST00000178006.8
1520401A03Rik
RIKEN cDNA 1520401A03 gene
chr9_-_81515865 0.81 ENSMUST00000183482.2
Htr1b
5-hydroxytryptamine (serotonin) receptor 1B
chr9_-_108183140 0.76 ENSMUST00000195615.2
Tcta
T cell leukemia translocation altered gene
chr19_+_10019023 0.75 ENSMUST00000237672.2
Fads3
fatty acid desaturase 3
chr14_+_63284438 0.71 ENSMUST00000067990.8
ENSMUST00000111203.2
Defb42
defensin beta 42
chr15_-_36792649 0.71 ENSMUST00000126184.2
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr7_-_140676623 0.69 ENSMUST00000209352.2
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_23883974 0.64 ENSMUST00000233541.2
Bicdl2
BICD family like cargo adaptor 2
chr9_-_95697441 0.63 ENSMUST00000119760.2
Pls1
plastin 1 (I-isoform)
chr10_+_93324624 0.58 ENSMUST00000129421.8
Hal
histidine ammonia lyase
chr4_-_41774097 0.52 ENSMUST00000108036.8
ENSMUST00000108037.9
ENSMUST00000108032.3
ENSMUST00000173865.9
ENSMUST00000155240.2
Ccl27a
chemokine (C-C motif) ligand 27A
chr12_+_87073338 0.49 ENSMUST00000110187.8
ENSMUST00000156162.8
Tmem63c
transmembrane protein 63c
chr9_-_108183162 0.48 ENSMUST00000044725.9
Tcta
T cell leukemia translocation altered gene
chr7_-_105218472 0.48 ENSMUST00000187683.7
ENSMUST00000210079.2
ENSMUST00000187051.7
ENSMUST00000189265.7
ENSMUST00000190369.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr12_+_87073060 0.47 ENSMUST00000146292.8
Tmem63c
transmembrane protein 63c
chr7_-_105217851 0.47 ENSMUST00000188368.7
ENSMUST00000187057.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chrX_-_101295787 0.42 ENSMUST00000050551.10
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr11_+_98592089 0.41 ENSMUST00000038886.3
Csf3
colony stimulating factor 3 (granulocyte)
chrX_-_101295458 0.38 ENSMUST00000101336.10
ENSMUST00000136277.2
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr1_+_135075377 0.35 ENSMUST00000125774.2
Arl8a
ADP-ribosylation factor-like 8A
chrX_+_7750558 0.35 ENSMUST00000208640.2
ENSMUST00000207114.2
ENSMUST00000208633.2
ENSMUST00000208397.2
ENSMUST00000153620.3
ENSMUST00000123277.8
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr3_-_88241735 0.33 ENSMUST00000107552.2
Tmem79
transmembrane protein 79
chr2_-_155849839 0.33 ENSMUST00000086145.10
ENSMUST00000144686.8
ENSMUST00000140657.8
6430550D23Rik
RIKEN cDNA 6430550D23 gene
chr9_-_44624496 0.26 ENSMUST00000144251.8
ENSMUST00000156918.8
Phldb1
pleckstrin homology like domain, family B, member 1
chr13_+_55468313 0.23 ENSMUST00000021942.8
Prelid1
PRELI domain containing 1
chr3_+_89987749 0.20 ENSMUST00000127955.2
Tpm3
tropomyosin 3, gamma
chr3_+_89173859 0.18 ENSMUST00000040824.2
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr7_-_142628298 0.11 ENSMUST00000148715.8
Trpm5
transient receptor potential cation channel, subfamily M, member 5
chr7_-_104246386 0.06 ENSMUST00000057385.5
Olfr655
olfactory receptor 655

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 1.8 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.3 1.6 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 0.8 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 0.8 GO:0071105 response to interleukin-11(GO:0071105)
0.2 2.1 GO:0072675 osteoclast fusion(GO:0072675)
0.2 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.9 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.6 GO:0006548 histidine catabolic process(GO:0006548)
0.1 0.5 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:1901857 negative regulation of mitochondrial membrane potential(GO:0010917) positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0051378 serotonin binding(GO:0051378)
0.0 0.8 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.9 GO:0048156 tau protein binding(GO:0048156)
0.0 3.5 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.6 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane