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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Lef1

Z-value: 1.33

Motif logo

Transcription factors associated with Lef1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027985.15 Lef1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lef1mm39_v1_chr3_+_130904000_130904120-0.343.7e-03Click!

Activity profile of Lef1 motif

Sorted Z-values of Lef1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Lef1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_76842263 12.58 ENSMUST00000082431.6
glutathione peroxidase 2
chr15_-_58078274 8.23 ENSMUST00000022986.8
F-box protein 32
chr2_+_121188195 7.37 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr14_+_102078038 7.16 ENSMUST00000159314.8
LIM domain only 7
chr11_+_96162283 7.14 ENSMUST00000000010.9
ENSMUST00000174042.3
homeobox B9
chr2_-_60503998 6.93 ENSMUST00000059888.15
ENSMUST00000154764.2
integrin beta 6
chr5_-_134975773 6.88 ENSMUST00000051401.4
claudin 4
chr16_-_97412169 6.61 ENSMUST00000232141.2
ENSMUST00000000395.8
transmembrane protease, serine 2
chr16_+_96001865 6.39 ENSMUST00000171181.9
ENSMUST00000233818.2
ENSMUST00000233945.2
ENSMUST00000166952.8
SH3-binding domain glutamic acid-rich protein
chr6_-_52217821 6.26 ENSMUST00000121043.2
homeobox A10
chr6_-_52141796 6.04 ENSMUST00000014848.11
homeobox A2
chr16_+_96001650 5.70 ENSMUST00000048770.16
SH3-binding domain glutamic acid-rich protein
chr13_-_63006176 5.69 ENSMUST00000021907.9
fructose bisphosphatase 2
chr17_+_35295909 5.68 ENSMUST00000013910.5
lymphocyte antigen 6 complex, locus G6E
chr14_-_61283911 5.57 ENSMUST00000111234.10
ENSMUST00000224371.2
tumor necrosis factor receptor superfamily, member 19
chr11_+_96820220 5.38 ENSMUST00000062172.6
proline rich 15-like
chr14_+_102077937 5.26 ENSMUST00000159026.8
LIM domain only 7
chr17_+_35295894 5.07 ENSMUST00000172678.8
lymphocyte antigen 6 complex, locus G6E
chr3_-_30563831 5.02 ENSMUST00000173495.8
MDS1 and EVI1 complex locus
chr6_-_52222776 4.91 ENSMUST00000048026.10
homeobox A11
chr3_-_30563919 4.75 ENSMUST00000172697.8
MDS1 and EVI1 complex locus
chr10_+_43455157 4.73 ENSMUST00000058714.10
CD24a antigen
chr8_+_89247976 4.69 ENSMUST00000034086.13
naked cuticle 1
chr11_+_96820091 4.54 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr3_-_141637245 4.47 ENSMUST00000106232.8
bone morphogenetic protein receptor, type 1B
chrX_+_162923474 4.40 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr17_+_48037758 4.36 ENSMUST00000024782.12
ENSMUST00000144955.2
progastricsin (pepsinogen C)
chr6_-_52211882 4.29 ENSMUST00000125581.2
homeobox A10
chr14_+_101967343 4.22 ENSMUST00000100337.10
LIM domain only 7
chr3_-_30563611 4.21 ENSMUST00000173899.8
MDS1 and EVI1 complex locus
chr5_+_17779721 4.16 ENSMUST00000169603.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_31409021 4.06 ENSMUST00000054829.13
ENSMUST00000201625.4
ENSMUST00000201937.4
keratinocyte associated protein 3
chr10_+_79658392 3.96 ENSMUST00000219305.2
ENSMUST00000046833.5
ENSMUST00000218687.2
mitotic spindle positioning
chr4_-_132990362 3.90 ENSMUST00000105908.10
ENSMUST00000030674.8
synaptotagmin-like 1
chr8_-_11362731 3.87 ENSMUST00000033898.10
collagen, type IV, alpha 1
chr8_+_11362805 3.79 ENSMUST00000033899.14
collagen, type IV, alpha 2
chr2_+_138120401 3.73 ENSMUST00000075410.5
BTB (POZ) domain containing 3
chr2_+_70305267 3.70 ENSMUST00000100043.3
trans-acting transcription factor 5
chr14_+_56062422 3.68 ENSMUST00000172271.9
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
chr19_+_55730696 3.64 ENSMUST00000153888.9
ENSMUST00000127233.9
ENSMUST00000061496.17
ENSMUST00000111656.8
ENSMUST00000111657.11
transcription factor 7 like 2, T cell specific, HMG box
chr2_-_115895528 3.58 ENSMUST00000028639.13
ENSMUST00000102538.11
Meis homeobox 2
chr3_-_89245297 3.57 ENSMUST00000029674.8
ephrin A4
chr16_+_96001915 3.56 ENSMUST00000132424.9
SH3-binding domain glutamic acid-rich protein
chr15_+_10952418 3.53 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr11_+_96214078 3.52 ENSMUST00000093944.10
homeobox B3
chr14_+_56062252 3.51 ENSMUST00000024179.6
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
chr13_-_113182891 3.51 ENSMUST00000231962.2
ENSMUST00000022282.6
glutathione peroxidase 8 (putative)
chr6_+_15185399 3.46 ENSMUST00000115474.8
ENSMUST00000115472.8
ENSMUST00000031545.14
forkhead box P2
chr15_-_100585789 3.38 ENSMUST00000023775.9
chymotrypsin-like elastase family, member 1
chr6_+_21985902 3.36 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr6_+_86605146 3.28 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr12_+_76118790 3.25 ENSMUST00000131480.8
spectrin repeat containing, nuclear envelope 2
chrX_+_72719098 3.24 ENSMUST00000171398.2
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_-_148846247 3.23 ENSMUST00000111562.8
ENSMUST00000081956.12
SIN3-HDAC complex associated factor
chr1_-_79417732 3.22 ENSMUST00000185234.2
ENSMUST00000049972.6
secretogranin II
chr17_+_35296056 3.20 ENSMUST00000172959.2
lymphocyte antigen 6 complex, locus G6E
chr17_+_35295849 3.20 ENSMUST00000172494.8
lymphocyte antigen 6 complex, locus G6E
chr6_+_17065141 3.16 ENSMUST00000115467.11
ENSMUST00000154266.3
ENSMUST00000076654.9
testin LIM domain protein
chr11_+_108811626 3.15 ENSMUST00000140821.2
axin 2
chr2_-_173118315 3.14 ENSMUST00000036248.13
prostate transmembrane protein, androgen induced 1
chr6_+_29735666 3.08 ENSMUST00000001812.5
smoothened, frizzled class receptor
chr1_+_131671751 3.07 ENSMUST00000049027.10
solute carrier family 26, member 9
chr11_+_96183294 3.05 ENSMUST00000173432.3
homeobox B6
chr11_+_73068063 3.04 ENSMUST00000108477.2
Tax1 (human T cell leukemia virus type I) binding protein 3
chr2_-_163239865 3.04 ENSMUST00000017961.11
ENSMUST00000109425.3
junctophilin 2
chr4_-_141325517 3.03 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr2_+_74552322 3.01 ENSMUST00000047904.4
homeobox D4
chr12_+_29988035 3.01 ENSMUST00000122328.8
ENSMUST00000118321.3
peroxidasin
chr2_+_103254465 2.98 ENSMUST00000171693.8
E74-like factor 5
chr10_+_38841511 2.97 ENSMUST00000019992.6
laminin, alpha 4
chr11_+_73067909 2.95 ENSMUST00000040687.12
Tax1 (human T cell leukemia virus type I) binding protein 3
chr19_-_38031774 2.94 ENSMUST00000226068.2
myoferlin
chr16_+_78727829 2.92 ENSMUST00000114216.2
ENSMUST00000069148.13
ENSMUST00000023568.14
chondrolectin
chr12_-_57592907 2.86 ENSMUST00000044380.8
forkhead box A1
chr5_-_147244074 2.83 ENSMUST00000031650.4
caudal type homeobox 2
chr2_+_103254401 2.83 ENSMUST00000028609.14
E74-like factor 5
chr11_+_108811168 2.82 ENSMUST00000052915.14
axin 2
chr10_+_21758083 2.80 ENSMUST00000120509.8
serum/glucocorticoid regulated kinase 1
chr4_+_85972125 2.80 ENSMUST00000107178.9
ENSMUST00000048885.12
ENSMUST00000141889.8
ENSMUST00000120678.2
ADAMTS-like 1
chr7_+_100143250 2.78 ENSMUST00000153287.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr3_-_141687987 2.76 ENSMUST00000029948.15
bone morphogenetic protein receptor, type 1B
chr18_-_61169262 2.74 ENSMUST00000025521.9
caudal type homeobox 1
chr18_+_35347983 2.74 ENSMUST00000235449.2
ENSMUST00000235269.2
catenin (cadherin associated protein), alpha 1
chr16_-_4950285 2.70 ENSMUST00000035672.5
periplakin
chr3_+_89122499 2.64 ENSMUST00000142051.8
ENSMUST00000119084.2
thrombospondin 3
chr1_-_186437760 2.61 ENSMUST00000195201.2
transforming growth factor, beta 2
chr3_+_89122477 2.59 ENSMUST00000029682.11
thrombospondin 3
chr17_-_71158184 2.54 ENSMUST00000059775.15
TGFB-induced factor homeobox 1
chr18_+_21205386 2.48 ENSMUST00000082235.5
meprin 1 beta
chr4_+_47208004 2.38 ENSMUST00000082303.13
ENSMUST00000102917.11
collagen, type XV, alpha 1
chr11_-_86964881 2.38 ENSMUST00000020804.8
glycerophosphodiester phosphodiesterase domain containing 1
chr16_+_95058417 2.37 ENSMUST00000113861.8
ENSMUST00000113854.8
ENSMUST00000113862.8
ENSMUST00000037154.14
ENSMUST00000113855.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_-_68311073 2.37 ENSMUST00000024840.12
Rho GTPase activating protein 28
chr8_+_45960804 2.35 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr2_+_74557418 2.35 ENSMUST00000111980.4
homeobox D4
chrX_+_157993303 2.33 ENSMUST00000112493.8
ribosomal protein S6 kinase polypeptide 3
chr4_+_41465134 2.32 ENSMUST00000030154.7
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr13_-_72111832 2.31 ENSMUST00000077337.9
Iroquois homeobox 1
chr2_-_34261121 2.30 ENSMUST00000127353.3
ENSMUST00000141653.3
pre B cell leukemia homeobox 3
chr12_+_76593799 2.29 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_173117936 2.29 ENSMUST00000139306.2
prostate transmembrane protein, androgen induced 1
chr6_+_21986445 2.28 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr18_+_11972277 2.27 ENSMUST00000171109.9
ENSMUST00000046948.10
CDK5 and Abl enzyme substrate 1
chr13_+_118851214 2.26 ENSMUST00000022246.9
fibroblast growth factor 10
chr15_-_50753061 2.26 ENSMUST00000165201.9
ENSMUST00000184458.8
transcriptional repressor GATA binding 1
chr10_-_85847697 2.25 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr16_+_44913974 2.24 ENSMUST00000099498.10
coiled-coil domain containing 80
chr3_-_51468236 2.23 ENSMUST00000037141.9
SET domain containing (lysine methyltransferase) 7
chr3_+_8574420 2.23 ENSMUST00000029002.9
stathmin-like 2
chr1_-_186438177 2.22 ENSMUST00000045288.14
transforming growth factor, beta 2
chr17_-_48716756 2.19 ENSMUST00000160319.8
ENSMUST00000159535.2
ENSMUST00000078800.13
ENSMUST00000046719.14
ENSMUST00000162460.8
nuclear transcription factor-Y alpha
chr2_+_31840340 2.17 ENSMUST00000148056.4
allograft inflammatory factor 1-like
chr6_-_94260806 2.16 ENSMUST00000203519.3
ENSMUST00000204347.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_-_12745109 2.16 ENSMUST00000218635.2
utrophin
chr19_+_55730316 2.14 ENSMUST00000111658.10
transcription factor 7 like 2, T cell specific, HMG box
chr17_-_71158052 2.13 ENSMUST00000186358.6
TGFB-induced factor homeobox 1
chr4_-_94538370 2.13 ENSMUST00000053419.9
leucine rich repeat containing 19
chr4_+_117706390 2.12 ENSMUST00000132043.9
ENSMUST00000169990.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_+_100142977 2.12 ENSMUST00000129324.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr18_-_15536747 2.11 ENSMUST00000079081.8
aquaporin 4
chr16_+_44914397 2.10 ENSMUST00000061050.6
coiled-coil domain containing 80
chr16_+_95058505 2.10 ENSMUST00000113856.8
ENSMUST00000125847.2
ENSMUST00000134166.8
ENSMUST00000140222.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_43672856 2.09 ENSMUST00000076939.10
C1q and tumor necrosis factor related protein 7
chr19_+_55730488 2.06 ENSMUST00000111659.9
transcription factor 7 like 2, T cell specific, HMG box
chr14_-_55344004 2.05 ENSMUST00000036041.15
adaptor protein complex AP-1, gamma 2 subunit
chr4_-_136563154 2.02 ENSMUST00000105846.9
ENSMUST00000059287.14
ENSMUST00000105845.9
Eph receptor B2
chr14_-_98406977 2.00 ENSMUST00000071533.13
ENSMUST00000069334.8
dachshund family transcription factor 1
chr11_-_76462353 2.00 ENSMUST00000072740.13
active BCR-related gene
chr3_-_57483175 1.98 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr14_+_70791496 1.97 ENSMUST00000022691.14
lysine demethylase and nuclear receptor corepressor
chr6_-_52195663 1.96 ENSMUST00000134367.4
homeobox A7
chr9_+_72600721 1.96 ENSMUST00000238315.2
neural precursor cell expressed, developmentally down-regulated 4
chr2_-_65397809 1.94 ENSMUST00000066432.12
sodium channel, voltage-gated, type III, alpha
chr2_-_65397850 1.93 ENSMUST00000238483.2
ENSMUST00000100069.9
sodium channel, voltage-gated, type III, alpha
chr4_+_62883796 1.91 ENSMUST00000030043.13
ENSMUST00000107415.8
ENSMUST00000064814.6
zinc finger protein 618
chr13_+_5911481 1.90 ENSMUST00000000080.8
Kruppel-like factor 6
chr1_+_107288928 1.90 ENSMUST00000191425.7
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr8_+_45960931 1.89 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr11_-_77380492 1.89 ENSMUST00000037593.14
ENSMUST00000092892.10
ankyrin repeat domain 13b
chr3_-_75864195 1.88 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr5_+_57875309 1.86 ENSMUST00000191837.6
ENSMUST00000068110.10
protocadherin 7
chr2_+_31840151 1.86 ENSMUST00000001920.13
ENSMUST00000151276.3
allograft inflammatory factor 1-like
chr10_+_69761597 1.86 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
ankyrin 3, epithelial
chr2_+_74535242 1.85 ENSMUST00000019749.4
homeobox D8
chr3_-_57483330 1.84 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chr7_-_144493560 1.84 ENSMUST00000093962.5
cyclin D1
chr14_-_50020788 1.83 ENSMUST00000118129.2
ENSMUST00000036972.14
armadillo-like helical domain containing 4
chr4_+_117706559 1.83 ENSMUST00000163288.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_+_157401998 1.80 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
neuronatin
chr12_+_21161779 1.79 ENSMUST00000050990.10
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr3_-_27950491 1.79 ENSMUST00000058077.4
transmembrane protein 212
chr6_+_48963795 1.78 ENSMUST00000037696.6
seminal vesicle secretory protein 1
chr15_-_54141816 1.78 ENSMUST00000079772.4
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr3_-_24837772 1.77 ENSMUST00000203414.2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr2_+_174602412 1.74 ENSMUST00000029030.9
endothelin 3
chr5_+_53748323 1.73 ENSMUST00000201883.4
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_47270201 1.73 ENSMUST00000077221.6
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr11_+_87959067 1.71 ENSMUST00000018521.11
vascular endothelial zinc finger 1
chr12_-_16850674 1.71 ENSMUST00000162112.8
gene regulated by estrogen in breast cancer protein
chr1_-_181847492 1.70 ENSMUST00000177811.8
ENSMUST00000111025.8
ENSMUST00000111024.10
ENAH actin regulator
chr6_+_125016723 1.69 ENSMUST00000140131.8
ENSMUST00000032480.14
inhibitor of growth family, member 4
chr19_-_28657477 1.69 ENSMUST00000162022.8
ENSMUST00000112612.9
GLIS family zinc finger 3
chr2_-_57004933 1.69 ENSMUST00000028166.9
nuclear receptor subfamily 4, group A, member 2
chr13_-_101831020 1.69 ENSMUST00000185795.2
phosphoinositide-3-kinase regulatory subunit 1
chr19_+_44980565 1.68 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_+_74505350 1.67 ENSMUST00000001878.6
homeobox D12
chr4_-_58499398 1.67 ENSMUST00000107570.2
lysophosphatidic acid receptor 1
chr10_+_69761784 1.66 ENSMUST00000181974.8
ENSMUST00000182795.8
ENSMUST00000182437.8
ankyrin 3, epithelial
chr8_+_93628015 1.65 ENSMUST00000104947.5
calpain, small subunit 2
chr5_-_148329615 1.65 ENSMUST00000138257.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_+_55730242 1.65 ENSMUST00000111662.11
ENSMUST00000041717.14
transcription factor 7 like 2, T cell specific, HMG box
chr3_+_7568481 1.65 ENSMUST00000051064.9
ENSMUST00000193010.2
zinc finger, C2HC-type containing 1A
chr13_-_105191403 1.65 ENSMUST00000063551.7
regulator of G-protein signalling 7 binding protein
chr8_+_79754980 1.63 ENSMUST00000087927.11
ENSMUST00000098614.9
zinc finger protein 827
chr10_+_102348076 1.62 ENSMUST00000219445.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr10_-_37014859 1.62 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr3_+_54063459 1.60 ENSMUST00000029311.11
ENSMUST00000200048.5
transient receptor potential cation channel, subfamily C, member 4
chr11_-_101676076 1.57 ENSMUST00000164750.8
ENSMUST00000107176.8
ENSMUST00000017868.7
ets variant 4
chr16_+_95058895 1.57 ENSMUST00000113859.8
ENSMUST00000152516.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_-_83533497 1.57 ENSMUST00000094216.5
talin rod domain containing 1
chr6_+_83011154 1.56 ENSMUST00000000707.9
ENSMUST00000101257.4
lysyl oxidase-like 3
chr15_+_102922247 1.56 ENSMUST00000001709.3
homeobox C5
chr11_-_106606076 1.56 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
platelet/endothelial cell adhesion molecule 1
chr9_-_71803354 1.56 ENSMUST00000184448.8
transcription factor 12
chr11_+_108814007 1.55 ENSMUST00000106711.2
axin 2
chrX_+_108138965 1.53 ENSMUST00000033598.9
SH3-binding domain glutamic acid-rich protein like
chr15_+_102898966 1.52 ENSMUST00000001703.8
homeobox C8
chr1_+_187730032 1.51 ENSMUST00000110938.2
estrogen-related receptor gamma
chr12_+_80565764 1.46 ENSMUST00000021558.8
polypeptide N-acetylgalactosaminyltransferase 16
chr2_-_75534985 1.46 ENSMUST00000102672.5
nuclear factor, erythroid derived 2, like 2
chr19_-_56996617 1.46 ENSMUST00000118800.8
ENSMUST00000111584.9
ENSMUST00000122359.8
ENSMUST00000148049.8
actin filament associated protein 1-like 2
chr11_-_106605772 1.45 ENSMUST00000124958.3
platelet/endothelial cell adhesion molecule 1
chr9_-_44646487 1.45 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr6_-_72766224 1.44 ENSMUST00000069536.12
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_-_72765935 1.44 ENSMUST00000114053.9
transcription factor 7 like 1 (T cell specific, HMG box)
chr18_+_4921663 1.42 ENSMUST00000143254.8
supervillin
chr17_+_48717007 1.41 ENSMUST00000167180.8
ENSMUST00000046651.7
ENSMUST00000233426.2
O-acyl-ADP-ribose deacylase 1
chr9_-_117701613 1.39 ENSMUST00000239475.2
RNA binding motif, single stranded interacting protein
chr2_-_170248421 1.39 ENSMUST00000154650.8
breast carcinoma amplified sequence 1
chr13_-_101829070 1.39 ENSMUST00000187009.7
phosphoinositide-3-kinase regulatory subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.6 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
2.7 8.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.8 7.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 4.8 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
1.6 4.7 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.5 6.0 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
1.4 7.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.4 8.6 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.3 3.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.3 5.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.1 11.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
1.1 4.4 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.1 3.2 GO:0015881 creatine transport(GO:0015881)
1.0 3.0 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
1.0 2.9 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
1.0 2.9 GO:0061144 alveolar secondary septum development(GO:0061144)
0.9 5.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.9 14.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.9 4.4 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.8 5.8 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.8 6.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.8 3.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.8 2.3 GO:0060447 bronchiole development(GO:0060435) bud outgrowth involved in lung branching(GO:0060447) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7 3.6 GO:0046684 response to pyrethroid(GO:0046684)
0.7 2.0 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.7 6.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.7 1.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.6 3.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.6 1.3 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.6 2.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 3.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.6 4.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.6 2.3 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.6 2.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 1.6 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.5 4.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 1.5 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.5 3.4 GO:0060309 elastin catabolic process(GO:0060309)
0.5 6.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 2.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.5 2.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.4 3.5 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.4 15.4 GO:1903831 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.4 5.2 GO:0060346 bone trabecula formation(GO:0060346)
0.4 1.3 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.4 15.9 GO:0060065 uterus development(GO:0060065)
0.4 3.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 5.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.4 1.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.4 2.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.4 1.7 GO:0017085 response to insecticide(GO:0017085)
0.4 2.1 GO:0070295 renal water absorption(GO:0070295)
0.4 1.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.4 1.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.4 3.3 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4 2.4 GO:0035128 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.4 1.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 3.8 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 3.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 2.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.3 1.7 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 2.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 1.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.3 1.3 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.3 2.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 4.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.3 0.9 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 7.5 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.3 2.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 2.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 1.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 0.8 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.3 1.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.7 GO:0060023 soft palate development(GO:0060023)
0.2 1.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 1.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.7 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.2 0.9 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 0.8 GO:0009196 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 4.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 3.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 1.6 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 2.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 3.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 2.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.6 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.2 1.8 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 4.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) activation of protein kinase C activity(GO:1990051)
0.2 2.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 4.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 2.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.8 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 1.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.2 2.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 2.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 4.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 0.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 3.4 GO:0008272 sulfate transport(GO:0008272)
0.2 2.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 3.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.4 GO:0070839 divalent metal ion export(GO:0070839)
0.1 1.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 0.6 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
0.1 1.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 5.1 GO:0035329 hippo signaling(GO:0035329)
0.1 1.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.8 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 2.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 3.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 6.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.7 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 2.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.7 GO:0015809 arginine transport(GO:0015809)
0.1 3.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 4.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 2.7 GO:0031424 keratinization(GO:0031424)
0.1 1.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.6 GO:0045056 transcytosis(GO:0045056)
0.1 1.9 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 3.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 14.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.7 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.6 GO:0042640 anagen(GO:0042640)
0.1 2.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 1.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.2 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0072189 ureter development(GO:0072189)
0.1 1.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.5 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.7 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 1.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0061299 extracellular matrix-cell signaling(GO:0035426) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 2.5 GO:1901998 toxin transport(GO:1901998)
0.0 3.4 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 3.4 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.9 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 1.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 1.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.0 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.7 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 4.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:0006301 postreplication repair(GO:0006301)
0.0 0.5 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.7 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.4 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.0 0.3 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 2.5 GO:0043588 skin development(GO:0043588)
0.0 1.6 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.5 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.2 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 2.4 GO:0016197 endosomal transport(GO:0016197)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0090102 cochlea development(GO:0090102)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 6.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.1 11.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.1 7.7 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
1.1 4.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 1.3 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.4 2.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 2.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 4.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 3.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 3.0 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.6 GO:0042585 germinal vesicle(GO:0042585)
0.3 2.9 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 1.0 GO:1902737 dendritic filopodium(GO:1902737)
0.2 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.2 6.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 6.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 3.1 GO:0044294 dendritic growth cone(GO:0044294)
0.2 1.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 4.7 GO:0031528 microvillus membrane(GO:0031528)
0.2 2.7 GO:0005915 zonula adherens(GO:0005915)
0.2 0.8 GO:0032444 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 4.1 GO:0005605 basal lamina(GO:0005605)
0.1 4.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 18.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 13.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 3.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.9 GO:0042599 lamellar body(GO:0042599)
0.1 9.4 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 1.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.9 GO:0045098 type III intermediate filament(GO:0045098)
0.1 5.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 7.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 7.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.5 GO:0070449 elongin complex(GO:0070449)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 4.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 30.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 9.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 8.0 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 3.8 GO:0005901 caveola(GO:0005901)
0.0 8.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 13.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.6 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 3.2 GO:0072562 blood microparticle(GO:0072562)
0.0 5.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 2.7 GO:0005819 spindle(GO:0005819)
0.0 2.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 29.6 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 17.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.1 3.2 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
1.0 7.2 GO:0004111 creatine kinase activity(GO:0004111)
0.8 4.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.8 4.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.7 4.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.7 4.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.6 7.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 2.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 9.4 GO:0070411 I-SMAD binding(GO:0070411)
0.5 16.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 1.7 GO:0005118 sevenless binding(GO:0005118)
0.4 1.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 1.9 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 2.6 GO:0001851 complement component C3b binding(GO:0001851)
0.3 2.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.0 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.3 2.4 GO:0015616 DNA translocase activity(GO:0015616)
0.3 7.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 2.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 2.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.0 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 0.9 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.3 2.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 5.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.3 3.1 GO:0005113 patched binding(GO:0005113)
0.3 8.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 6.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 0.8 GO:0070401 NADP+ binding(GO:0070401)
0.3 1.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 2.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 3.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 7.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 2.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 4.2 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.8 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.2 1.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 2.1 GO:0015288 porin activity(GO:0015288)
0.2 5.4 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 4.0 GO:0070410 co-SMAD binding(GO:0070410)
0.2 4.9 GO:0017166 vinculin binding(GO:0017166)
0.2 3.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 3.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 7.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 2.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 14.9 GO:0042805 actinin binding(GO:0042805)
0.2 2.7 GO:0005522 profilin binding(GO:0005522)
0.2 0.3 GO:0015116 sulfate transmembrane transporter activity(GO:0015116)
0.1 4.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 4.3 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 6.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 3.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.9 GO:1990254 keratin filament binding(GO:1990254)
0.1 4.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.2 GO:0031005 filamin binding(GO:0031005)
0.1 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 2.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 16.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 6.0 GO:0030507 spectrin binding(GO:0030507)
0.1 4.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.0 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 10.6 GO:0051015 actin filament binding(GO:0051015)
0.0 2.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 2.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 3.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 5.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 5.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 7.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 7.7 GO:0045296 cadherin binding(GO:0045296)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.8 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 15.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 11.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 8.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 6.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 14.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 14.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 9.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 6.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 8.2 PID BMP PATHWAY BMP receptor signaling
0.1 12.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 7.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 15.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 6.5 PID FOXO PATHWAY FoxO family signaling
0.1 6.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 11.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 9.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 10.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 6.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 2.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 6.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 5.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 3.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 6.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 17.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 5.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 4.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 5.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 4.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 3.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 3.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.5 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis