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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Mafb

Z-value: 1.44

Motif logo

Transcription factors associated with Mafb

Gene Symbol Gene ID Gene Info
ENSMUSG00000074622.5 Mafb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafbmm39_v1_chr2_-_160208977_160208993-0.019.4e-01Click!

Activity profile of Mafb motif

Sorted Z-values of Mafb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_92496293 16.37 ENSMUST00000098888.7
sperm mitochondria-associated cysteine-rich protein
chr17_-_28299569 13.02 ENSMUST00000129046.9
ENSMUST00000043925.16
t-complex protein 11
chr4_-_96552349 11.74 ENSMUST00000030299.8
cytochrome P450, family 2, subfamily j, polypeptide 5
chr7_+_46510677 10.20 ENSMUST00000211784.2
ENSMUST00000210585.2
ENSMUST00000148565.8
lactate dehydrogenase C
chr7_+_46510627 10.15 ENSMUST00000014545.11
lactate dehydrogenase C
chr17_-_15198955 9.87 ENSMUST00000231584.2
ENSMUST00000097399.6
ENSMUST00000232173.2
dynein light chain Tctex-type 2A3
chr17_-_15261701 9.54 ENSMUST00000097398.12
ENSMUST00000040746.8
ENSMUST00000097400.5
dynein light chain Tctex-type 2A1
dynein light chain Tctex-type 2A2
chr7_+_46510831 9.21 ENSMUST00000126004.3
lactate dehydrogenase C
chr4_+_150203740 8.55 ENSMUST00000030826.4
solute carrier family 2 (facilitated glucose transporter), member 5
chr16_-_10606513 8.23 ENSMUST00000051297.9
transition protein 2
chr6_+_128639342 7.71 ENSMUST00000032518.7
ENSMUST00000204416.2
C-type lectin domain family 2, member h
chr8_+_88290469 7.01 ENSMUST00000093342.6
RIKEN cDNA 4933402J07 gene
chr11_+_115768323 6.95 ENSMUST00000222123.2
myosin XVB
chr2_+_148677060 6.91 ENSMUST00000028935.4
cystatin 9
chr19_+_42040681 6.91 ENSMUST00000164518.4
RIKEN cDNA 4933411K16 gene
chr1_+_75336965 6.70 ENSMUST00000027409.10
desmin
chr1_-_120001752 6.63 ENSMUST00000056089.8
transmembrane protein 37
chr11_-_73029070 6.46 ENSMUST00000052140.3
histone H3 associated protein kinase
chr9_+_24536487 6.35 ENSMUST00000053956.8
cysteine-rich perinuclear theca 4
chr2_-_180284468 6.23 ENSMUST00000037877.11
transcription factor-like 5 (basic helix-loop-helix)
chr17_-_12894716 6.10 ENSMUST00000024596.10
solute carrier family 22 (organic cation transporter), member 1
chr8_-_25215778 5.94 ENSMUST00000171438.8
ENSMUST00000171611.9
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr2_+_180861804 5.92 ENSMUST00000050026.7
ENSMUST00000108835.2
fibronectin type III domain containing 11
chr13_-_55563028 5.92 ENSMUST00000054146.5
profilin 3
chr12_+_35034747 5.84 ENSMUST00000134550.3
phosphoribosyl pyrophosphate synthetase 1-like 1
chr11_+_67167950 5.80 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr2_-_162929732 5.53 ENSMUST00000094653.6
gametocyte specific factor 1-like
chr2_+_104961228 5.53 ENSMUST00000111098.8
ENSMUST00000111099.2
Wilms tumor 1 homolog
chr7_+_143028831 5.45 ENSMUST00000105917.3
solute carrier family 22 (organic cation transporter), member 18
chr8_-_25215856 5.41 ENSMUST00000033958.15
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr4_+_140815644 5.34 ENSMUST00000051907.3
spermatogenesis associated 21
chr16_-_36810810 5.27 ENSMUST00000075869.13
F-box protein 40
chrX_+_156482116 5.23 ENSMUST00000112521.8
small muscle protein, X-linked
chr7_+_140343652 5.05 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr10_+_75409282 5.04 ENSMUST00000006508.10
gamma-glutamyltransferase 1
chr8_+_105652867 4.86 ENSMUST00000034355.11
ENSMUST00000109410.4
carboxylesterase 2E
chr11_-_102298281 4.83 ENSMUST00000107098.8
ENSMUST00000018821.9
solute carrier family 25, member 39
chrX_-_161747552 4.79 ENSMUST00000038769.3
S100 calcium binding protein G
chr13_-_41373638 4.73 ENSMUST00000117096.2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr2_-_60552980 4.62 ENSMUST00000028348.9
ENSMUST00000112517.8
integrin beta 6
chr14_-_20502285 4.60 ENSMUST00000056073.14
ENSMUST00000022349.14
ENSMUST00000022348.15
cilia and flagella associated protein 70
chr17_+_44499451 4.53 ENSMUST00000024755.7
chloride intracellular channel 5
chr12_+_85793313 4.53 ENSMUST00000040461.4
feline leukemia virus subgroup C cellular receptor 2
chr3_-_51184895 4.46 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr19_-_7779943 4.46 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr3_-_129126362 4.40 ENSMUST00000029658.14
glutamyl aminopeptidase
chr11_+_70350252 4.38 ENSMUST00000108563.9
zinc finger, MYND-type containing 15
chr11_-_102298141 4.33 ENSMUST00000149777.8
ENSMUST00000154001.8
solute carrier family 25, member 39
chr1_+_64729950 4.24 ENSMUST00000187170.7
cyclin Y-like 1
chr6_-_70895899 4.24 ENSMUST00000063456.5
testis expressed 37
chr17_-_56607250 4.23 ENSMUST00000233911.2
arrestin domain containing 5
chr19_-_7780025 4.22 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chrX_+_16389108 4.21 ENSMUST00000115422.2
ENSMUST00000024026.3
cysteine-rich perinuclear theca 1
chr6_+_32027216 4.21 ENSMUST00000031778.6
RIKEN cDNA 1700012A03 gene
chr19_-_11058452 4.15 ENSMUST00000025636.8
membrane-spanning 4-domains, subfamily A, member 8A
chr10_+_127541039 4.13 ENSMUST00000079590.7
myosin IA
chr13_-_23894697 4.12 ENSMUST00000091707.13
ENSMUST00000006787.8
homeostatic iron regulator
chr7_+_35148188 4.11 ENSMUST00000118383.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr8_+_46463633 4.02 ENSMUST00000110381.9
Lrp2 binding protein
chr10_-_62198043 4.01 ENSMUST00000149534.2
hexokinase 1
chr3_+_40905216 4.01 ENSMUST00000191872.6
ENSMUST00000200432.2
La ribonucleoprotein domain family, member 1B
chr6_-_40917431 3.96 ENSMUST00000122181.8
ENSMUST00000031935.10
RIKEN cDNA 1700074P13 gene
chr7_-_97387145 3.96 ENSMUST00000084986.8
aquaporin 11
chr11_+_70350436 3.85 ENSMUST00000039093.10
zinc finger, MYND-type containing 15
chr11_-_102297590 3.83 ENSMUST00000155104.8
ENSMUST00000130436.8
solute carrier family 25, member 39
chr9_+_107424488 3.83 ENSMUST00000010188.9
zinc finger, MYND domain containing 10
chr2_-_69036489 3.80 ENSMUST00000127243.8
ENSMUST00000149643.2
ENSMUST00000167875.9
ENSMUST00000005365.15
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_86354045 3.79 ENSMUST00000046004.6
testis expressed 44
chr13_+_24925192 3.76 ENSMUST00000136906.2
armadillo-like helical domain containing 2
chr15_-_89294434 3.74 ENSMUST00000109314.9
synaptonemal complex central element protein 3
chr13_+_50797264 3.72 ENSMUST00000099519.2
predicted gene 904
chr8_-_84738761 3.71 ENSMUST00000191523.2
ENSMUST00000190457.2
ENSMUST00000185457.2
MISP family member 3
chr6_-_135287372 3.71 ENSMUST00000050471.4
phosphatidylethanolamine binding protein 2
chr12_+_56742413 3.71 ENSMUST00000001538.10
paired box 9
chr18_+_21094477 3.71 ENSMUST00000234316.2
ring finger protein 125
chr10_-_75617245 3.70 ENSMUST00000001715.10
glutathione S-transferase, theta 3
chr12_-_16696958 3.70 ENSMUST00000238839.2
lipin 1
chr11_+_48728291 3.69 ENSMUST00000046903.6
tripartite motif-containing 7
chr2_+_110427643 3.69 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr7_-_97387429 3.66 ENSMUST00000206389.2
aquaporin 11
chrX_+_156481906 3.63 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr2_-_3420056 3.55 ENSMUST00000115084.8
ENSMUST00000115083.8
meiosis expressed gene 1
chr9_+_44309727 3.51 ENSMUST00000213268.2
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr2_-_32584132 3.49 ENSMUST00000028148.11
folylpolyglutamyl synthetase
chr1_-_92830604 3.46 ENSMUST00000160548.8
ENSMUST00000112998.2
ankyrin repeat and MYND domain containing 1
chr4_+_138694422 3.45 ENSMUST00000116094.5
ENSMUST00000239443.2
ring finger protein 186
chr7_+_127399789 3.43 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_-_3420102 3.42 ENSMUST00000115082.10
meiosis expressed gene 1
chr7_+_29883611 3.38 ENSMUST00000208441.2
cytochrome c oxidase subunit 7A1
chr15_+_82439273 3.36 ENSMUST00000229103.2
ENSMUST00000068861.8
ENSMUST00000229904.2
cytochrome P450, family 2, subfamily d, polypeptide 12
chr11_+_119119925 3.35 ENSMUST00000053440.8
coiled-coil domain containing 40
chr6_-_72367642 3.34 ENSMUST00000059983.10
vesicle-associated membrane protein 8
chr2_+_104956850 3.31 ENSMUST00000143043.8
Wilms tumor 1 homolog
chr14_-_64322849 3.31 ENSMUST00000089338.6
ENSMUST00000171503.8
protease, serine 55
chrX_+_104543374 3.30 ENSMUST00000041758.5
cysteine-rich perinuclear theca 2
chr19_-_47825790 3.30 ENSMUST00000160247.3
cilia and flagella associated protein 43
chr5_-_15734220 3.30 ENSMUST00000196384.2
predicted gene, 21190
chr13_-_23894828 3.24 ENSMUST00000091706.14
homeostatic iron regulator
chr4_-_86587728 3.24 ENSMUST00000149700.8
perilipin 2
chr11_-_53313950 3.22 ENSMUST00000036045.6
liver-expressed antimicrobial peptide 2
chr15_+_25843225 3.21 ENSMUST00000022881.15
reticulophagy regulator 1
chr6_+_29279582 3.20 ENSMUST00000167131.8
family with sequence similarity 71, member F2
chr19_-_20931566 3.18 ENSMUST00000039500.4
transmembrane channel-like gene family 1
chrX_+_8970801 3.16 ENSMUST00000059967.2
RIKEN cDNA 4930402K13 gene
chr3_+_59989282 3.15 ENSMUST00000029326.6
succinate receptor 1
chr13_-_50404344 3.14 ENSMUST00000099521.2
predicted gene 906
chr2_+_3714492 3.14 ENSMUST00000027965.11
family with sequence similarity 107, member B
chr14_-_54647647 3.12 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr17_-_29161229 3.12 ENSMUST00000051526.6
ENSMUST00000233413.2
peroxisomal, testis specific 1
chr16_-_85698679 3.10 ENSMUST00000023611.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr11_+_75542328 3.07 ENSMUST00000069057.13
myosin IC
chr2_-_69036472 3.06 ENSMUST00000112320.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr5_-_14964913 3.04 ENSMUST00000035980.9
predicted gene 9758
chr15_-_100579450 3.04 ENSMUST00000230740.2
chymotrypsin-like elastase family, member 1
chr5_-_139805661 3.02 ENSMUST00000147328.2
transmembrane protein 184a
chr14_-_54648057 3.00 ENSMUST00000200545.2
ENSMUST00000227967.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_+_3714515 2.99 ENSMUST00000115053.9
family with sequence similarity 107, member B
chr5_-_15919234 2.97 ENSMUST00000095005.12
ENSMUST00000179506.2
spermatogenesis associated glutamate (E)-rich protein 4C
chr5_-_107873883 2.97 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr6_+_29471436 2.96 ENSMUST00000171317.2
Atp6v1f neighbor
chr11_-_69696428 2.96 ENSMUST00000051025.5
transmembrane protein 102
chr15_-_5093222 2.94 ENSMUST00000110689.5
complement component 7
chr5_-_15681521 2.94 ENSMUST00000197995.2
predicted gene, 21149
chr15_-_100579813 2.93 ENSMUST00000230572.2
chymotrypsin-like elastase family, member 1
chrX_-_78715030 2.92 ENSMUST00000052283.7
MAGE family member B16
chr1_-_121255503 2.91 ENSMUST00000160688.2
insulin induced gene 2
chr1_+_167177545 2.90 ENSMUST00000028004.11
aldehyde dehydrogenase 9, subfamily A1
chr12_+_65272495 2.83 ENSMUST00000221980.2
WD repeat domain 20, retrogene
chr19_-_20704896 2.81 ENSMUST00000025656.4
aldehyde dehydrogenase family 1, subfamily A7
chr11_-_94398162 2.81 ENSMUST00000040692.9
MYCBP associated protein
chr1_-_121255753 2.79 ENSMUST00000003818.14
insulin induced gene 2
chr5_+_15782286 2.77 ENSMUST00000188807.4
predicted gene, 21083
chr15_+_82338247 2.74 ENSMUST00000230000.2
cytochrome P450, family 2, subfamily d, polypeptide 9
chr1_-_161807205 2.70 ENSMUST00000162676.2
RIKEN cDNA 4930558K02 gene
chr5_-_121756928 2.67 ENSMUST00000041252.13
ENSMUST00000111776.6
acyl-Coenzyme A dehydrogenase family, member 12
chr2_-_27136826 2.63 ENSMUST00000149733.8
sarcosine dehydrogenase
chr7_+_140427711 2.62 ENSMUST00000026555.12
outer dense fiber of sperm tails 3
chr9_+_45314436 2.61 ENSMUST00000041005.6
FXYD domain-containing ion transport regulator 2
chr15_+_31224616 2.60 ENSMUST00000186547.7
death-associated protein
chr7_+_40682143 2.59 ENSMUST00000164422.2
predicted gene 4884
chr8_+_117822593 2.58 ENSMUST00000034308.16
ENSMUST00000176860.2
beta-carotene oxygenase 1
chr5_-_15028949 2.56 ENSMUST00000096953.5
predicted gene 10354
chr15_+_25933632 2.54 ENSMUST00000228327.2
reticulophagy regulator 1
chr8_-_123302187 2.53 ENSMUST00000213062.2
adenine phosphoribosyl transferase
chr2_+_164131181 2.51 ENSMUST00000017147.8
ENSMUST00000109370.2
seminal vesicle secretory protein 3A
chr5_-_15083012 2.48 ENSMUST00000167908.2
predicted gene 17019
chr12_-_16660960 2.48 ENSMUST00000239165.2
ENSMUST00000111067.10
lipin 1
chr11_+_75542902 2.46 ENSMUST00000102504.10
myosin IC
chr15_-_59888446 2.46 ENSMUST00000096421.4
RIKEN cDNA 4933412E24 gene
chr5_-_14988443 2.44 ENSMUST00000159973.3
spermatogenesis associated glutamate (E)-rich protein 4e
chr11_-_109364424 2.42 ENSMUST00000070152.12
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_-_127673738 2.41 ENSMUST00000028858.8
BUB1, mitotic checkpoint serine/threonine kinase
chr6_+_40763875 2.40 ENSMUST00000195870.3
maltase-glucoamylase 2, pseudogene
chr14_+_22069709 2.40 ENSMUST00000075639.11
leucine rich melanocyte differentiation associated
chr5_-_26193648 2.40 ENSMUST00000191203.7
predicted gene, 21698
chr5_+_20112771 2.39 ENSMUST00000200443.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_17578178 2.38 ENSMUST00000166086.3
spermatogenesis associated glutamate (E)-rich protein 4f2
chr11_-_116197994 2.37 ENSMUST00000124281.2
exocyst complex component 7
chr1_+_64729603 2.37 ENSMUST00000114077.8
cyclin Y-like 1
chr12_+_65272287 2.37 ENSMUST00000046331.5
ENSMUST00000221658.2
WD repeat domain 20, retrogene
chr10_-_129738595 2.36 ENSMUST00000071557.2
olfactory receptor 815
chr14_-_34032311 2.35 ENSMUST00000111917.3
ENSMUST00000228704.2
shieldin complex subunit 2
chr14_-_34310438 2.34 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr10_+_70040483 2.33 ENSMUST00000020090.8
myoregulin
chr7_+_140427729 2.33 ENSMUST00000106049.2
outer dense fiber of sperm tails 3
chr5_+_17681096 2.32 ENSMUST00000076099.4
spermatogenesis associated glutamate (E)-rich protein 4F1
chr7_-_39062584 2.32 ENSMUST00000108017.2
predicted gene 5114
chr1_+_54369151 2.28 ENSMUST00000163072.8
coiled-coil domain containing 150
chr14_-_66361931 2.26 ENSMUST00000070515.2
epoxide hydrolase 2, cytoplasmic
chr1_-_121255400 2.25 ENSMUST00000159085.8
ENSMUST00000159125.2
ENSMUST00000161818.2
insulin induced gene 2
chr5_-_15862057 2.24 ENSMUST00000092696.5
RIKEN cDNA 4930572O03 gene
chr7_+_127399776 2.23 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_-_24423715 2.21 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr11_-_83412952 2.20 ENSMUST00000019069.4
HEAT repeat containing 9
chr9_-_107556823 2.19 ENSMUST00000010205.9
guanine nucleotide binding protein, alpha transducing 1
chr13_+_4283729 2.18 ENSMUST00000081326.7
aldo-keto reductase family 1, member C19
chr17_+_34617784 2.17 ENSMUST00000114175.8
ENSMUST00000139063.8
ENSMUST00000078615.12
cDNA sequence BC051142
chr7_-_30443106 2.17 ENSMUST00000182634.8
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_-_121009503 2.16 ENSMUST00000039146.4
testis expressed gene 19.2
chr15_-_75801575 2.16 ENSMUST00000229951.2
ENSMUST00000023231.7
ENSMUST00000230736.2
GDP-L-fucose synthase
chr15_-_79212323 2.15 ENSMUST00000166977.9
phospholipase A2, group VI
chr15_-_76193955 2.14 ENSMUST00000210024.2
5-oxoprolinase (ATP-hydrolysing)
chr11_+_106265660 2.12 ENSMUST00000188561.7
ENSMUST00000190795.7
ENSMUST00000185986.7
ENSMUST00000190268.2
proline rich 29
chr3_+_108444837 2.11 ENSMUST00000029485.6
RIKEN cDNA 1700013F07 gene
chr11_-_102815910 2.10 ENSMUST00000021311.10
kinesin family member 18B
chr19_-_44534274 2.07 ENSMUST00000111985.2
ENSMUST00000063632.14
Sec31 homolog B (S. cerevisiae)
chr5_-_27706360 2.04 ENSMUST00000155721.2
ENSMUST00000053257.10
spermatogenesis associated glutamate (E)-rich protein 4B
chr9_-_103165489 2.04 ENSMUST00000035163.10
RIKEN cDNA 1300017J02 gene
chr11_+_82006001 2.02 ENSMUST00000009329.3
chemokine (C-C motif) ligand 8
chrX_+_122925694 2.02 ENSMUST00000238503.2
predicted gene 5945
chr15_-_56557920 2.02 ENSMUST00000050544.8
hyaluronan synthase 2
chr3_+_14545751 1.98 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr12_+_84085136 1.96 ENSMUST00000021652.5
acyl-CoA thioesterase 4
chr1_-_121255448 1.95 ENSMUST00000186915.2
ENSMUST00000160968.8
ENSMUST00000162582.2
insulin induced gene 2
chr12_+_104082229 1.95 ENSMUST00000021496.8
serine (or cysteine) peptidase inhibitor, clade A, member 3A
chr11_+_106265645 1.94 ENSMUST00000106816.8
proline rich 29
chrX_+_122256461 1.94 ENSMUST00000238410.2
predicted gene 2411
chr15_-_75801630 1.94 ENSMUST00000229289.2
ENSMUST00000229641.2
GDP-L-fucose synthase
chr2_-_152775122 1.93 ENSMUST00000099200.3
forkhead box S1
chr4_+_98284054 1.93 ENSMUST00000107033.8
ENSMUST00000107034.8
PATJ, crumbs cell polarity complex component

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.6 GO:0019516 lactate oxidation(GO:0019516)
3.9 11.7 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
3.3 13.0 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.1 24.6 GO:0007341 penetration of zona pellucida(GO:0007341)
2.9 8.8 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
2.5 7.4 GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
2.2 6.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
2.1 8.6 GO:0015755 fructose transport(GO:0015755)
1.9 7.6 GO:0048388 endosomal lumen acidification(GO:0048388)
1.2 3.5 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
1.1 4.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.0 4.1 GO:0015811 L-cystine transport(GO:0015811)
1.0 6.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.9 2.6 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.9 6.0 GO:0060309 elastin catabolic process(GO:0060309)
0.8 3.3 GO:1902276 autophagosome docking(GO:0016240) pancreatic amylase secretion(GO:0036395) zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) regulation of pancreatic amylase secretion(GO:1902276)
0.8 6.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.8 2.3 GO:1900673 olefin metabolic process(GO:1900673)
0.7 3.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.7 5.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.7 2.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.7 4.0 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.7 2.0 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.6 5.7 GO:0061709 reticulophagy(GO:0061709)
0.6 2.5 GO:0006168 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.6 5.0 GO:0031179 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 4.4 GO:0002003 angiotensin maturation(GO:0002003)
0.6 2.5 GO:0045297 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.6 9.4 GO:0015747 urate transport(GO:0015747)
0.6 6.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.6 2.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.6 9.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 3.2 GO:0060005 vestibular reflex(GO:0060005)
0.5 1.6 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.5 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 6.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.5 4.6 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.5 3.0 GO:0018992 germ-line sex determination(GO:0018992)
0.5 8.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.5 7.7 GO:0006968 cellular defense response(GO:0006968)
0.5 2.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.4 1.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 4.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 3.5 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.4 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.9 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 2.2 GO:0050917 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.4 13.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.3 1.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 3.0 GO:0032264 IMP salvage(GO:0032264)
0.3 0.9 GO:0036034 mediator complex assembly(GO:0036034) DNA replication preinitiation complex assembly(GO:0071163) response to sorbitol(GO:0072708) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.3 5.8 GO:0030049 muscle filament sliding(GO:0030049)
0.3 1.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 1.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 3.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 0.7 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 11.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 1.7 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 4.5 GO:0002024 diet induced thermogenesis(GO:0002024)
0.2 1.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 2.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 2.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.4 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.2 1.0 GO:0009597 detection of virus(GO:0009597)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 2.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 5.0 GO:0017144 drug metabolic process(GO:0017144)
0.2 1.6 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 2.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.2 0.2 GO:0050942 positive regulation of developmental pigmentation(GO:0048087) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942)
0.2 1.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 0.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 1.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 4.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 2.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 6.9 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 0.4 GO:1904156 DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
0.1 1.0 GO:0030035 microspike assembly(GO:0030035)
0.1 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.6 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 1.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.6 GO:0033504 floor plate development(GO:0033504)
0.1 2.7 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 2.6 GO:0042574 retinal metabolic process(GO:0042574)
0.1 2.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 4.1 GO:0030033 microvillus assembly(GO:0030033)
0.1 1.6 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 4.5 GO:0015893 drug transport(GO:0015893)
0.1 1.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 9.0 GO:0030317 sperm motility(GO:0030317)
0.1 0.7 GO:0051608 histamine transport(GO:0051608)
0.1 3.3 GO:0045109 intermediate filament organization(GO:0045109)
0.1 3.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 6.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.8 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 4.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 6.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 2.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.4 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 2.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 5.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 36.0 GO:0007283 spermatogenesis(GO:0007283)
0.1 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.0 0.7 GO:0008272 sulfate transport(GO:0008272)
0.0 0.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 1.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 1.0 GO:0006706 steroid catabolic process(GO:0006706)
0.0 3.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 3.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.9 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.1 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 1.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 4.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 4.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 6.9 GO:0007059 chromosome segregation(GO:0007059)
0.0 1.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 6.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.7 GO:0045214 sarcomere organization(GO:0045214)
0.0 2.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.3 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.1 6.9 GO:0031262 Ndc80 complex(GO:0031262)
1.1 8.9 GO:0005927 muscle tendon junction(GO:0005927)
1.1 5.5 GO:0045160 myosin I complex(GO:0045160)
0.9 4.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.8 7.4 GO:1990357 terminal web(GO:1990357)
0.8 2.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.6 6.7 GO:0045098 type III intermediate filament(GO:0045098)
0.6 14.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 13.9 GO:0097225 sperm midpiece(GO:0097225)
0.3 3.7 GO:0000801 central element(GO:0000801)
0.3 2.9 GO:0005579 membrane attack complex(GO:0005579)
0.3 4.4 GO:0031983 vesicle lumen(GO:0031983)
0.3 4.2 GO:0001520 outer dense fiber(GO:0001520)
0.3 2.4 GO:0042825 TAP complex(GO:0042825)
0.3 3.7 GO:0005818 aster(GO:0005818)
0.3 0.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 1.0 GO:0008623 CHRAC(GO:0008623)
0.2 2.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.3 GO:0032437 cuticular plate(GO:0032437)
0.2 5.8 GO:0032982 myosin filament(GO:0032982)
0.2 3.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.4 GO:0097441 basilar dendrite(GO:0097441)
0.2 6.2 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.3 GO:0002177 manchette(GO:0002177)
0.2 36.8 GO:0031514 motile cilium(GO:0031514)
0.1 1.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 3.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 2.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 6.0 GO:0032420 stereocilium(GO:0032420)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 22.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 5.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.9 GO:0042581 specific granule(GO:0042581)
0.1 4.1 GO:0031941 filamentous actin(GO:0031941)
0.1 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 9.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 23.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.4 GO:0005811 lipid particle(GO:0005811)
0.0 4.4 GO:0045177 apical part of cell(GO:0045177)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 3.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.9 GO:0005903 brush border(GO:0005903)
0.0 5.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.0 GO:0097361 CIA complex(GO:0097361)
0.0 0.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 4.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 2.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
2.7 29.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
2.0 6.1 GO:0005333 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
1.6 6.6 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.6 6.5 GO:0072354 histone kinase activity (H3-T3 specific)(GO:0072354)
1.3 8.8 GO:0010385 double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729)
1.2 3.5 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
1.2 3.5 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
1.0 4.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.9 2.6 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.8 2.5 GO:0002055 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.8 4.5 GO:0015232 heme transporter activity(GO:0015232)
0.7 2.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6 1.9 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.6 4.8 GO:0005499 vitamin D binding(GO:0005499)
0.6 7.4 GO:0039706 co-receptor binding(GO:0039706)
0.6 2.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 9.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5 20.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.5 1.5 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.5 2.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 2.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 1.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.4 2.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 1.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 7.6 GO:0015250 water channel activity(GO:0015250)
0.4 5.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 3.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 4.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.4 4.7 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 0.4 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.4 7.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.4 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 1.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.3 3.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 6.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 1.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 3.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 3.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 2.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 7.8 GO:0000146 microfilament motor activity(GO:0000146)
0.2 1.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 6.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.7 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.2 4.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 4.5 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.2 1.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 2.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 3.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 1.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 2.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.6 GO:0070513 death domain binding(GO:0070513)
0.1 5.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 3.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 6.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 2.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 3.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.6 GO:0032052 bile acid binding(GO:0032052)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.2 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 7.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 5.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 8.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 10.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0015297 antiporter activity(GO:0015297)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 4.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 3.8 GO:0005178 integrin binding(GO:0005178)
0.0 3.0 GO:0005506 iron ion binding(GO:0005506)
0.0 2.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.2 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 5.3 GO:0003779 actin binding(GO:0003779)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 9.1 PID AURORA B PATHWAY Aurora B signaling
0.1 8.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 5.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 14.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 2.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.8 12.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.6 9.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 6.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 1.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 5.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 9.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 13.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 9.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 6.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 5.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 9.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.9 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 4.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis