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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Mef2b

Z-value: 1.44

Motif logo

Transcription factors associated with Mef2b

Gene Symbol Gene ID Gene Info
ENSMUSG00000079033.11 Mef2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2bmm39_v1_chr8_+_70592337_705923840.161.7e-01Click!

Activity profile of Mef2b motif

Sorted Z-values of Mef2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_61096660 10.79 ENSMUST00000039904.7
calcium/calmodulin-dependent protein kinase II alpha
chr18_+_61096597 10.50 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr7_-_127805518 9.94 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr4_+_46039202 9.45 ENSMUST00000156200.8
tropomodulin 1
chr11_-_79394904 9.08 ENSMUST00000164465.3
oligodendrocyte myelin glycoprotein
chr4_-_134099840 8.76 ENSMUST00000030643.3
exostosin-like glycosyltransferase 1
chr8_-_46664321 8.43 ENSMUST00000034049.5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr6_-_71239216 8.30 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr9_+_121606750 8.21 ENSMUST00000098272.4
kelch-like 40
chr15_-_98705791 7.54 ENSMUST00000075444.8
dendrin
chr4_-_42856771 7.31 ENSMUST00000107981.2
predicted gene 12394
chr14_-_52151537 7.01 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr13_-_113800172 6.86 ENSMUST00000054650.5
heat shock protein 3
chr5_+_25964985 6.82 ENSMUST00000128727.8
ENSMUST00000088244.6
ARP3 actin-related protein 3B
chr15_+_101152078 6.75 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr2_+_136555364 6.66 ENSMUST00000028727.11
ENSMUST00000110098.4
synaptosomal-associated protein 25
chr15_+_101164719 6.36 ENSMUST00000230814.2
ENSMUST00000023779.8
nuclear receptor subfamily 4, group A, member 1
chr8_+_31579499 6.30 ENSMUST00000036631.14
dual specificity phosphatase 26 (putative)
chr3_-_122828592 6.28 ENSMUST00000029761.14
myozenin 2
chr14_-_52151026 6.25 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr14_+_26616514 6.11 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr3_+_68491487 6.05 ENSMUST00000182997.3
schwannomin interacting protein 1
chr1_-_66974492 6.05 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr3_+_32871669 5.85 ENSMUST00000072312.12
ENSMUST00000108228.8
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr12_-_40249314 5.79 ENSMUST00000095760.3
leucine-rich single-pass membrane protein 1
chr8_+_31579633 5.72 ENSMUST00000170204.8
dual specificity phosphatase 26 (putative)
chr16_-_28571820 5.60 ENSMUST00000232352.2
fibroblast growth factor 12
chr7_+_44984681 5.59 ENSMUST00000085351.7
histidine rich calcium binding protein
chr8_+_15107646 5.50 ENSMUST00000033842.4
myomesin 2
chr11_+_67689094 5.49 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr14_-_51134930 5.45 ENSMUST00000227271.2
kelch-like 33
chr6_+_42263609 5.32 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr17_-_26056056 5.23 ENSMUST00000183929.8
ENSMUST00000184865.2
ENSMUST00000026831.14
rhomboid like 1
chr14_-_20706556 5.13 ENSMUST00000090469.8
myozenin 1
chr12_-_40249489 5.12 ENSMUST00000220951.2
leucine-rich single-pass membrane protein 1
chr1_-_66974694 5.09 ENSMUST00000186202.7
myosin, light polypeptide 1
chr10_-_70428611 5.00 ENSMUST00000162251.8
phytanoyl-CoA hydroxylase interacting protein-like
chr11_+_54195006 5.00 ENSMUST00000108904.10
ENSMUST00000108905.10
acyl-CoA synthetase long-chain family member 6
chr7_-_25374472 4.91 ENSMUST00000108404.8
ENSMUST00000108405.2
ENSMUST00000079439.10
transmembrane protein 91
chr7_-_142453722 4.85 ENSMUST00000000219.10
tyrosine hydroxylase
chr4_-_73869071 4.73 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr3_+_146558114 4.72 ENSMUST00000170055.8
ENSMUST00000037942.11
tubulin tyrosine ligase-like family, member 7
chr1_+_9618173 4.60 ENSMUST00000144177.8
alcohol dehydrogenase, iron containing, 1
chr3_-_158267771 4.59 ENSMUST00000199890.5
ENSMUST00000238317.3
ENSMUST00000200137.5
ENSMUST00000106044.6
leucine rich repeat containing 7
chrX_+_156481906 4.58 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr12_+_69288606 4.58 ENSMUST00000063445.13
kelch domain containing 1
chr2_+_69500444 4.55 ENSMUST00000100050.4
kelch-like 41
chr14_-_51134906 4.47 ENSMUST00000170855.2
kelch-like 33
chr3_+_96503944 4.35 ENSMUST00000058943.8
ankyrin repeat domain 34A
chr15_+_98065039 4.32 ENSMUST00000031914.6
coiled-coil domain containing 184
chr7_+_80707328 4.31 ENSMUST00000107348.2
alpha-kinase 3
chr2_-_17395765 4.29 ENSMUST00000177966.2
nebulette
chr2_+_90948481 4.23 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr7_-_105230479 4.07 ENSMUST00000191601.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr10_+_32959472 4.01 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chrX_+_163221035 3.99 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr10_-_88440869 3.87 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr11_+_54194831 3.85 ENSMUST00000000145.12
ENSMUST00000138515.8
acyl-CoA synthetase long-chain family member 6
chr2_+_120294046 3.84 ENSMUST00000028749.15
ENSMUST00000110721.9
ENSMUST00000239364.2
calpain 3
chr8_+_23548541 3.84 ENSMUST00000173248.8
ankyrin 1, erythroid
chrY_-_1286623 3.76 ENSMUST00000091190.12
DEAD box helicase 3, Y-linked
chr6_+_42263644 3.75 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr5_+_66903174 3.70 ENSMUST00000101164.11
ENSMUST00000238785.2
LIM and calponin homology domains 1
chr3_-_113368407 3.69 ENSMUST00000106540.8
amylase 1, salivary
chr17_+_34258411 3.68 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
collagen, type XI, alpha 2
chr18_-_25886908 3.65 ENSMUST00000115816.3
ENSMUST00000223704.2
CUGBP, Elav-like family member 4
chr7_+_140343652 3.64 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr14_+_55813074 3.62 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr5_+_122239007 3.61 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr1_-_172156884 3.61 ENSMUST00000062387.8
potassium inwardly-rectifying channel, subfamily J, member 9
chr7_+_90739904 3.58 ENSMUST00000107196.10
ENSMUST00000074273.10
discs large MAGUK scaffold protein 2
chr1_-_172047282 3.58 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr2_-_79738773 3.53 ENSMUST00000102652.10
ENSMUST00000102651.10
phosphodiesterase 1A, calmodulin-dependent
chr4_+_156300325 3.53 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr7_+_141996067 3.53 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr7_-_101749433 3.52 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr6_-_55109960 3.51 ENSMUST00000003568.15
corticotropin releasing hormone receptor 2
chr5_+_122239030 3.45 ENSMUST00000139213.8
ENSMUST00000111751.8
ENSMUST00000155612.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr15_+_73620213 3.33 ENSMUST00000053232.8
protein tyrosine phosphatase 4a3
chr6_-_112924205 3.23 ENSMUST00000088373.11
SLIT-ROBO Rho GTPase activating protein 3
chr7_+_81512421 3.19 ENSMUST00000119543.2
transmembrane 6 superfamily member 1
chr5_-_116560916 3.19 ENSMUST00000036991.5
heat shock protein 8
chr11_+_73051228 3.19 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_+_12597490 3.16 ENSMUST00000014578.7
plasminogen
chr1_-_80642969 3.14 ENSMUST00000190983.7
ENSMUST00000191449.2
dedicator of cytokinesis 10
chr2_-_79738734 3.12 ENSMUST00000090756.11
phosphodiesterase 1A, calmodulin-dependent
chr2_+_67276338 3.11 ENSMUST00000239060.2
ENSMUST00000028410.4
ENSMUST00000112347.8
ENSMUST00000238878.2
xin actin-binding repeat containing 2
chr18_-_3299536 2.97 ENSMUST00000129435.8
ENSMUST00000122958.8
cAMP responsive element modulator
chr1_+_75351914 2.97 ENSMUST00000087122.12
SPEG complex locus
chr8_-_106670014 2.96 ENSMUST00000038896.8
lecithin cholesterol acyltransferase
chr6_-_112923715 2.96 ENSMUST00000113169.9
SLIT-ROBO Rho GTPase activating protein 3
chr1_-_80643024 2.87 ENSMUST00000187774.7
dedicator of cytokinesis 10
chr18_+_67597929 2.86 ENSMUST00000025411.9
PRELI domain containing 3A
chr18_-_25887173 2.84 ENSMUST00000225477.2
CUGBP, Elav-like family member 4
chr6_+_48566540 2.81 ENSMUST00000204521.2
predicted gene 45021
chr7_-_48497771 2.76 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr13_-_74512111 2.76 ENSMUST00000022064.5
leucine rich repeat containing 14B
chr8_-_84169107 2.71 ENSMUST00000212031.2
ENSMUST00000167525.3
short coiled-coil protein
chr2_-_171885386 2.71 ENSMUST00000087950.4
cerebellin 4 precursor protein
chr1_-_172156828 2.70 ENSMUST00000194204.2
potassium inwardly-rectifying channel, subfamily J, member 9
chr11_-_94867153 2.67 ENSMUST00000103162.8
ENSMUST00000166320.8
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr7_-_105230395 2.65 ENSMUST00000188726.2
ENSMUST00000188440.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr11_+_104468107 2.64 ENSMUST00000106956.10
myosin, light polypeptide 4
chr9_+_102382949 2.64 ENSMUST00000039390.6
kyphoscoliosis peptidase
chr10_+_90412827 2.63 ENSMUST00000182550.8
ENSMUST00000099364.12
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_-_88604404 2.60 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr7_+_127603083 2.58 ENSMUST00000106248.8
tripartite motif-containing 72
chrX_+_156482116 2.58 ENSMUST00000112521.8
small muscle protein, X-linked
chr11_+_54194624 2.56 ENSMUST00000093106.12
acyl-CoA synthetase long-chain family member 6
chr15_-_89310060 2.48 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr7_+_15863679 2.46 ENSMUST00000211649.2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_-_54554483 2.37 ENSMUST00000128163.8
acyl-CoA synthetase bubblegum family member 1
chr10_-_18619658 2.30 ENSMUST00000215836.2
ARFGEF family member 3
chr6_-_128503666 2.29 ENSMUST00000143664.2
ENSMUST00000112132.8
PZP, alpha-2-macroglobulin like
chr11_+_70548513 2.28 ENSMUST00000134087.8
enolase 3, beta muscle
chr11_+_70548022 2.27 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr1_-_24626492 2.27 ENSMUST00000051344.6
ENSMUST00000115244.9
collagen, type XIX, alpha 1
chr7_+_29821340 2.27 ENSMUST00000098596.11
ENSMUST00000153792.2
zinc finger protein 382
chr12_-_84993695 2.26 ENSMUST00000169161.8
apoptosis resistant E3 ubiquitin protein ligase 1
chr11_+_105069591 2.26 ENSMUST00000106939.9
tousled-like kinase 2 (Arabidopsis)
chr11_+_104467791 2.25 ENSMUST00000106957.8
myosin, light polypeptide 4
chr2_+_91086489 2.18 ENSMUST00000154959.8
ENSMUST00000059566.11
protein kinase C and casein kinase substrate in neurons 3
chr17_-_33049169 2.14 ENSMUST00000201499.2
ENSMUST00000201876.4
ENSMUST00000202759.2
ENSMUST00000202988.4
zinc finger protein 799
chr14_-_20718337 2.10 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr1_-_75195127 2.08 ENSMUST00000079464.13
tubulin, alpha 4A
chr5_+_66903195 2.06 ENSMUST00000118242.8
LIM and calponin homology domains 1
chr15_-_102630589 2.06 ENSMUST00000023818.11
calcium binding and coiled coil domain 1
chr7_+_120276801 2.02 ENSMUST00000208454.2
ENSMUST00000060175.8
modulator of smoothened
chr15_-_89309998 2.00 ENSMUST00000168376.2
carnitine palmitoyltransferase 1b, muscle
chr2_+_118493713 1.98 ENSMUST00000099557.10
p21 (RAC1) activated kinase 6
chr1_+_36411312 1.98 ENSMUST00000179162.7
fer-1-like 5 (C. elegans)
chr14_+_29700319 1.91 ENSMUST00000224797.2
ARP8 actin-related protein 8
chr19_-_46958001 1.81 ENSMUST00000235234.2
5'-nucleotidase, cytosolic II
chr6_-_68857658 1.79 ENSMUST00000198756.2
predicted gene 42543
chr9_+_110948492 1.79 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr14_+_29700294 1.76 ENSMUST00000016115.6
ARP8 actin-related protein 8
chr6_+_121277186 1.75 ENSMUST00000064580.14
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr2_+_43638814 1.74 ENSMUST00000112824.8
ENSMUST00000055776.8
Rho GTPase activating protein 15
chr6_-_124942366 1.72 ENSMUST00000129446.8
ENSMUST00000032220.15
COP9 signalosome subunit 7A
chr18_+_37093321 1.69 ENSMUST00000192168.2
protocadherin alpha 5
chr10_-_117074501 1.67 ENSMUST00000159193.8
ENSMUST00000020392.5
RIKEN cDNA 9530003J23 gene
chrX_-_94521712 1.66 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr4_+_116008623 1.65 ENSMUST00000106494.3
protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
chr2_-_160169414 1.62 ENSMUST00000099127.3
predicted gene 826
chr7_+_141995545 1.61 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr18_-_3281089 1.61 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chrX_-_63320543 1.58 ENSMUST00000114679.2
ENSMUST00000069926.14
SLIT and NTRK-like family, member 4
chr8_+_95584146 1.57 ENSMUST00000211939.2
ENSMUST00000212124.2
polymerase (RNA) II (DNA directed) polypeptide C
chr19_-_37153436 1.57 ENSMUST00000142973.2
ENSMUST00000154376.8
cytoplasmic polyadenylation element binding protein 3
chr5_-_3943907 1.55 ENSMUST00000117463.2
ENSMUST00000044746.5
mitochondrial transcription termination factor 1a
chr11_+_102159558 1.52 ENSMUST00000036467.5
ankyrin repeat and SOCS box-containing 16
chr6_+_137387718 1.52 ENSMUST00000167002.4
protein tyrosine phosphatase, receptor type, O
chr1_-_173707677 1.52 ENSMUST00000190651.4
ENSMUST00000188804.7
myeloid nuclear differentiation antigen like
chr5_+_120614587 1.44 ENSMUST00000201684.4
ENSMUST00000066540.14
serine dehydratase
chr19_-_40175709 1.42 ENSMUST00000051846.13
cytochrome P450, family 2, subfamily c, polypeptide 70
chr9_+_74959259 1.42 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr13_+_89687915 1.41 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr10_-_39775182 1.40 ENSMUST00000178045.9
ENSMUST00000178563.3
major facilitator superfamily domain containing 4B4
chr1_-_39844467 1.38 ENSMUST00000171319.4
predicted gene 3646
chr6_-_124942457 1.37 ENSMUST00000112439.9
COP9 signalosome subunit 7A
chr18_+_60426444 1.34 ENSMUST00000171297.2
RIKEN cDNA F830016B08 gene
chr1_-_14374794 1.34 ENSMUST00000190337.7
EYA transcriptional coactivator and phosphatase 1
chr1_+_155433858 1.32 ENSMUST00000080138.13
ENSMUST00000035560.9
ENSMUST00000097529.5
acyl-Coenzyme A binding domain containing 6
chr3_-_154302679 1.31 ENSMUST00000052774.8
ENSMUST00000170461.8
ENSMUST00000122976.2
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr4_-_115911053 1.29 ENSMUST00000030475.3
NOL1/NOP2/Sun domain family, member 4
chr3_+_101993731 1.28 ENSMUST00000029454.12
calsequestrin 2
chr13_-_23553327 1.28 ENSMUST00000125328.2
ENSMUST00000145451.8
ENSMUST00000050101.9
zinc finger protein 322A
chr18_-_3299452 1.24 ENSMUST00000126578.8
cAMP responsive element modulator
chr18_+_37898633 1.23 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr3_-_154760978 1.22 ENSMUST00000064076.6
TNNI3 interacting kinase
chr14_-_21764638 1.22 ENSMUST00000073870.7
dual specificity phosphatase and pro isomerase domain containing 1
chr1_-_160958998 1.18 ENSMUST00000111611.8
kelch-like 20
chr9_-_110819639 1.17 ENSMUST00000198702.2
receptor transporter protein 3
chr13_+_83672389 1.16 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr9_-_119852624 1.16 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chr5_-_24652775 1.14 ENSMUST00000123167.2
ENSMUST00000030799.15
transmembrane and ubiquitin-like domain containing 1
chr16_-_17019352 1.13 ENSMUST00000090192.12
ubiquitin-conjugating enzyme E2L 3
chr12_-_65010124 1.13 ENSMUST00000021331.9
kelch-like 28
chr7_-_12552764 1.12 ENSMUST00000108546.2
ENSMUST00000072222.8
zinc finger protein 329
chr18_-_80243812 1.12 ENSMUST00000025462.7
ribosome binding factor A
chr2_-_111779785 1.11 ENSMUST00000099604.6
olfactory receptor 1307
chr7_+_27878894 1.11 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr5_+_21990251 1.10 ENSMUST00000239497.2
ENSMUST00000030769.7
proteasome (prosome, macropain) 26S subunit, ATPase 2
chr3_-_20209220 1.09 ENSMUST00000184552.2
glycogenin
chr6_-_35516700 1.09 ENSMUST00000201026.2
ENSMUST00000031866.9
myotrophin
chr3_+_101993787 1.08 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr13_-_67229566 1.06 ENSMUST00000109742.11
ENSMUST00000190566.3
zinc finger protein 708
chr14_+_47886748 1.01 ENSMUST00000190252.7
ENSMUST00000186466.3
kinectin 1
chr12_-_34956910 1.00 ENSMUST00000239321.2
histone deacetylase 9
chr18_+_37646674 0.98 ENSMUST00000061405.6
protocadherin beta 21
chr13_-_23553139 0.96 ENSMUST00000152557.8
zinc finger protein 322A
chr2_+_25572737 0.95 ENSMUST00000058912.3
lipocalin 10
chr2_-_85966272 0.95 ENSMUST00000216566.3
ENSMUST00000214364.2
olfactory receptor 1039
chr8_-_112718888 0.94 ENSMUST00000034427.12
ENSMUST00000139820.8
adenosine deaminase, tRNA-specific 1
chr6_+_137387729 0.93 ENSMUST00000203914.2
protein tyrosine phosphatase, receptor type, O
chr16_-_58930996 0.93 ENSMUST00000076262.4
olfactory receptor 193
chr9_-_19799300 0.93 ENSMUST00000079660.5
olfactory receptor 862
chr1_-_173770010 0.93 ENSMUST00000042228.15
ENSMUST00000081216.12
ENSMUST00000129829.8
ENSMUST00000123708.8
interferon activated gene 203
chr1_+_15382676 0.93 ENSMUST00000170146.3
potassium voltage gated channel, Shab-related subfamily, member 2
chr5_+_20112704 0.92 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 12.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.4 7.1 GO:0042694 muscle cell fate specification(GO:0042694)
2.3 11.4 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
2.2 6.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
2.2 13.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.1 8.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
1.6 13.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.5 21.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
1.5 5.9 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
1.4 5.6 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.4 9.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.1 5.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.1 6.7 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.1 10.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.0 4.9 GO:0042414 epinephrine metabolic process(GO:0042414)
1.0 3.8 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.9 2.8 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.9 8.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.9 3.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 3.5 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.7 3.7 GO:0060023 soft palate development(GO:0060023)
0.7 4.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.6 9.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.6 3.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 9.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 2.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 1.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.5 1.5 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.5 6.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.5 3.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 6.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.4 9.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.4 4.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 1.8 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.4 2.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 6.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.5 GO:0036343 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 4.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.3 2.4 GO:0071313 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) cellular response to caffeine(GO:0071313)
0.3 2.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 2.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 3.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 2.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 5.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.2 6.1 GO:0001553 luteinization(GO:0001553)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.6 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.2 2.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 3.5 GO:0014850 response to muscle activity(GO:0014850)
0.2 0.4 GO:0003169 coronary vein morphogenesis(GO:0003169)
0.2 3.6 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 3.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.2 1.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 9.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 2.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.8 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.2 3.1 GO:0000338 protein deneddylation(GO:0000338)
0.2 2.6 GO:0001778 plasma membrane repair(GO:0001778)
0.2 5.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.7 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.3 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
0.1 1.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 10.7 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.4 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 1.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 30.0 GO:0006941 striated muscle contraction(GO:0006941)
0.1 6.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 6.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.6 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.1 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.4 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.1 0.3 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 6.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 1.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 3.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.2 GO:2000424 T-helper 1 cell lineage commitment(GO:0002296) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 1.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 3.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 3.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 5.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 2.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.2 GO:0048007 positive regulation of interleukin-4 biosynthetic process(GO:0045404) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 2.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 2.0 GO:0007520 myoblast fusion(GO:0007520)
0.0 4.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.6 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 1.6 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 10.4 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 4.6 GO:0006818 hydrogen transport(GO:0006818)
0.0 2.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 5.7 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 2.6 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 1.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.2 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.9 GO:0007566 embryo implantation(GO:0007566)
0.0 2.9 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.5 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.8 GO:0070229 negative regulation of lymphocyte apoptotic process(GO:0070229)
0.0 0.4 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.8 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 4.0 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.6 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 2.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.9 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 2.3 GO:0030198 extracellular matrix organization(GO:0030198)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.3 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
2.0 5.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.8 5.5 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
1.4 4.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.3 6.7 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.0 4.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.9 7.2 GO:0005927 muscle tendon junction(GO:0005927)
0.6 6.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.6 4.9 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 3.2 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.5 9.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 5.1 GO:0005861 troponin complex(GO:0005861)
0.4 7.1 GO:0097512 cardiac myofibril(GO:0097512)
0.4 28.1 GO:0031672 A band(GO:0031672)
0.3 6.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 4.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 9.5 GO:0036379 myofilament(GO:0036379)
0.3 5.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 3.5 GO:0070852 cell body fiber(GO:0070852)
0.2 4.6 GO:0043194 axon initial segment(GO:0043194)
0.2 3.7 GO:0031011 Ino80 complex(GO:0031011)
0.2 3.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.6 GO:0005916 fascia adherens(GO:0005916)
0.1 11.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 1.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 28.3 GO:0030016 myofibril(GO:0030016)
0.1 3.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 8.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 24.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 3.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 11.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 12.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 4.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 8.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0005672 RNA polymerase I transcription factor complex(GO:0000120) transcription factor TFIIA complex(GO:0005672)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 4.6 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 6.8 GO:0030425 dendrite(GO:0030425)
0.0 4.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 21.6 GO:0005739 mitochondrion(GO:0005739)
0.0 1.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0044297 cell body(GO:0044297)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
2.3 11.4 GO:0051373 FATZ binding(GO:0051373)
2.0 12.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.3 21.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.2 4.9 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
1.2 4.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.2 5.9 GO:1904288 BAT3 complex binding(GO:1904288)
1.2 3.5 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.9 3.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.8 4.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.8 8.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.7 4.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.7 6.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.7 2.8 GO:0031433 telethonin binding(GO:0031433)
0.7 13.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 1.2 GO:0031013 troponin I binding(GO:0031013)
0.6 6.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6 1.7 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.5 3.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.5 10.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 5.1 GO:0031014 troponin T binding(GO:0031014)
0.5 3.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 1.4 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.5 2.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.5 9.5 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.3 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.4 9.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 3.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 9.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 2.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 4.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.8 GO:0031432 titin binding(GO:0031432)
0.3 5.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.3 10.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 2.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 12.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 3.2 GO:1990405 protein antigen binding(GO:1990405)
0.2 6.7 GO:0048156 tau protein binding(GO:0048156)
0.2 2.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.6 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.2 0.6 GO:0035375 zymogen binding(GO:0035375)
0.2 6.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.2 GO:0019961 interferon binding(GO:0019961)
0.2 2.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 1.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 1.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 2.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 3.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 5.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.6 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.7 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 5.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 6.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 6.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 8.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 5.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.1 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 3.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.2 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0001129 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 3.8 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 31.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.2 GO:0035198 AT DNA binding(GO:0003680) miRNA binding(GO:0035198)
0.0 0.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 6.7 GO:0044325 ion channel binding(GO:0044325)
0.0 2.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 4.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 1.6 GO:0005550 pheromone binding(GO:0005550)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 23.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 7.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 10.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 6.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 5.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 11.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 6.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 10.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 6.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 6.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.6 41.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.6 21.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.5 6.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 11.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 13.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 4.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 6.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 4.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 8.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 8.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 6.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 6.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 9.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 11.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 6.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 4.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.7 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle