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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Mef2c

Z-value: 4.43

Motif logo

Transcription factors associated with Mef2c

Gene Symbol Gene ID Gene Info
ENSMUSG00000005583.17 Mef2c

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2cmm39_v1_chr13_+_83720457_837204760.491.3e-05Click!

Activity profile of Mef2c motif

Sorted Z-values of Mef2c motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2c

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_98274637 85.09 ENSMUST00000008021.3
titin-cap
chr10_+_32959472 79.86 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr11_-_59029996 59.94 ENSMUST00000219084.3
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr15_-_76906832 59.23 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr5_+_122239007 58.65 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr5_+_122239030 56.33 ENSMUST00000139213.8
ENSMUST00000111751.8
ENSMUST00000155612.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr7_-_127805518 49.62 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr19_+_6434416 48.49 ENSMUST00000035269.15
ENSMUST00000113483.2
muscle glycogen phosphorylase
chr11_+_67689094 48.47 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr3_-_122828592 46.77 ENSMUST00000029761.14
myozenin 2
chr8_+_15107646 45.75 ENSMUST00000033842.4
myomesin 2
chr14_-_34310637 45.13 ENSMUST00000227819.2
LIM domain binding 3
chr14_-_32407203 44.78 ENSMUST00000096038.4
RIKEN cDNA 3425401B19 gene
chr2_+_67276338 44.36 ENSMUST00000239060.2
ENSMUST00000028410.4
ENSMUST00000112347.8
ENSMUST00000238878.2
xin actin-binding repeat containing 2
chr14_-_20714634 43.73 ENSMUST00000119483.2
synaptopodin 2-like
chr14_-_34310602 43.63 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr3_+_96432479 43.48 ENSMUST00000049208.11
hemojuvelin BMP co-receptor
chr9_+_110592709 43.23 ENSMUST00000079784.12
myosin, light polypeptide 3
chr1_+_40844739 43.13 ENSMUST00000114765.4
transmembrane protein 182
chr11_+_70548022 42.73 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr14_-_20718337 41.84 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr9_-_119852624 41.30 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chr5_-_113044216 41.13 ENSMUST00000086617.11
myosin XVIIIb
chr7_-_48497771 40.49 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr1_-_66974492 39.82 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr1_-_66974694 38.83 ENSMUST00000186202.7
myosin, light polypeptide 1
chr14_+_26616514 37.55 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr4_+_130202388 37.31 ENSMUST00000070532.8
fatty acid binding protein 3, muscle and heart
chr7_+_101750943 37.27 ENSMUST00000033300.4
ADP-ribosyltransferase 1
chr11_+_70548513 36.40 ENSMUST00000134087.8
enolase 3, beta muscle
chr13_-_32960379 36.36 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr8_+_55024446 36.02 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr9_+_77543776 35.63 ENSMUST00000057781.8
kelch-like 31
chr6_-_71239216 35.59 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr14_-_34310438 35.39 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr7_+_127603083 35.35 ENSMUST00000106248.8
tripartite motif-containing 72
chr6_-_14755249 35.33 ENSMUST00000045096.6
protein phosphatase 1, regulatory subunit 3A
chr6_+_112250719 34.55 ENSMUST00000032376.6
LIM and cysteine-rich domains 1
chr1_-_172047282 34.55 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr7_-_81216687 34.10 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr3_+_32871669 33.81 ENSMUST00000072312.12
ENSMUST00000108228.8
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr2_+_69500444 33.59 ENSMUST00000100050.4
kelch-like 41
chrX_+_163221035 33.37 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr17_+_71326510 33.26 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr13_-_74512111 33.18 ENSMUST00000022064.5
leucine rich repeat containing 14B
chr3_+_101993787 33.12 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr11_+_77353218 33.12 ENSMUST00000102493.8
coronin 6
chr11_-_94867153 32.76 ENSMUST00000103162.8
ENSMUST00000166320.8
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr3_+_101993731 31.57 ENSMUST00000029454.12
calsequestrin 2
chr17_+_71326542 31.40 ENSMUST00000179759.3
myomesin 1
chr5_-_24745436 31.10 ENSMUST00000048302.13
ENSMUST00000119657.2
ankyrin repeat and SOCS box-containing 10
chr15_-_78090591 30.41 ENSMUST00000120592.2
parvalbumin
chr4_+_46039202 30.28 ENSMUST00000156200.8
tropomodulin 1
chr14_+_55813074 29.95 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr4_+_156300325 29.52 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr11_-_69838971 29.46 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr11_-_120538928 29.24 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr4_-_73869071 28.19 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr7_+_141995545 28.03 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr7_+_141996067 27.89 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr11_+_82802079 27.15 ENSMUST00000018989.14
ENSMUST00000164945.3
unc-45 myosin chaperone B
chr3_-_142101339 26.77 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr7_+_142052569 26.71 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr15_-_89310060 26.52 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr5_-_129907878 26.51 ENSMUST00000026617.13
phosphorylase kinase gamma 1
chr2_-_76812799 25.82 ENSMUST00000011934.13
ENSMUST00000099981.10
ENSMUST00000099980.10
ENSMUST00000111882.9
ENSMUST00000140091.8
titin
chr13_-_113800172 24.97 ENSMUST00000054650.5
heat shock protein 3
chr9_+_121606750 24.88 ENSMUST00000098272.4
kelch-like 40
chr14_-_55204092 23.80 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr2_+_90948481 23.70 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr14_-_55204054 23.25 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr5_-_18093739 21.97 ENSMUST00000169095.6
ENSMUST00000197574.2
CD36 molecule
chr5_-_24745970 21.64 ENSMUST00000117900.8
ankyrin repeat and SOCS box-containing 10
chr6_-_55109960 21.61 ENSMUST00000003568.15
corticotropin releasing hormone receptor 2
chr4_+_135975243 20.99 ENSMUST00000102533.11
ENSMUST00000143942.2
transcription elongation factor A (SII), 3
chr7_+_80707328 20.89 ENSMUST00000107348.2
alpha-kinase 3
chr12_-_103304573 20.49 ENSMUST00000149431.2
ankyrin repeat and SOCS box-containing 2
chr12_+_112586501 20.38 ENSMUST00000180015.9
adenylosuccinate synthetase like 1
chrX_-_94521712 19.79 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr11_+_67128843 19.05 ENSMUST00000018632.11
myosin, heavy polypeptide 4, skeletal muscle
chr14_-_55204383 19.02 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr10_+_127337541 18.96 ENSMUST00000160019.8
ENSMUST00000160610.2
ENSMUST00000035839.3
SH3 and cysteine rich domain 3
chr14_-_51134930 18.94 ENSMUST00000227271.2
kelch-like 33
chr9_+_102382949 18.81 ENSMUST00000039390.6
kyphoscoliosis peptidase
chr3_+_68491487 18.73 ENSMUST00000182997.3
schwannomin interacting protein 1
chr9_-_101076198 18.67 ENSMUST00000066773.9
protein phosphatase 2, regulatory subunit B'', alpha
chr5_+_92534738 18.39 ENSMUST00000128246.8
ADP-ribosyltransferase 3
chr6_+_42263609 18.23 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr4_-_9643636 18.16 ENSMUST00000108333.8
ENSMUST00000108334.8
ENSMUST00000108335.8
ENSMUST00000152526.8
ENSMUST00000103004.10
aspartate-beta-hydroxylase
chr2_+_91086489 18.15 ENSMUST00000154959.8
ENSMUST00000059566.11
protein kinase C and casein kinase substrate in neurons 3
chr10_-_88440869 18.11 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr1_-_44059089 18.08 ENSMUST00000061421.4
methyltransferase like 21C
chr19_+_4053290 17.72 ENSMUST00000025806.5
double C2, gamma
chr6_-_55109826 17.66 ENSMUST00000164012.3
ENSMUST00000212633.2
corticotropin releasing hormone receptor 2
chrX_+_72818003 17.54 ENSMUST00000002081.6
serine/arginine-rich protein specific kinase 3
chr19_+_4053367 17.49 ENSMUST00000236482.2
double C2, gamma
chr7_-_126399208 17.19 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr11_+_73051228 17.10 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_101749433 16.99 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr1_-_39844467 16.95 ENSMUST00000171319.4
predicted gene 3646
chr17_+_44499451 16.87 ENSMUST00000024755.7
chloride intracellular channel 5
chr2_+_32518402 16.74 ENSMUST00000156578.8
adenylate kinase 1
chr11_+_120839879 16.58 ENSMUST00000154187.8
ENSMUST00000100130.10
ENSMUST00000129473.8
ENSMUST00000168579.8
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr7_-_126399778 16.55 ENSMUST00000141355.4
aldolase A, fructose-bisphosphate
chr10_-_88440996 16.46 ENSMUST00000121629.8
myosin binding protein C, slow-type
chr1_-_89942299 16.35 ENSMUST00000086882.8
ENSMUST00000097656.10
ankyrin repeat and SOCS box-containing 18
chr14_-_51134906 16.33 ENSMUST00000170855.2
kelch-like 33
chr15_-_89309998 16.32 ENSMUST00000168376.2
carnitine palmitoyltransferase 1b, muscle
chr4_+_123095297 16.15 ENSMUST00000068262.6
5'-nucleotidase, cytosolic IA
chr12_+_52746158 15.93 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr3_+_102981326 15.84 ENSMUST00000090715.13
ENSMUST00000155034.6
adenosine monophosphate deaminase 1
chr14_-_55204023 15.53 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr2_+_3514071 15.50 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr5_+_135916764 15.23 ENSMUST00000005077.7
heat shock protein 1
chr3_-_126918491 15.22 ENSMUST00000238781.2
ankyrin 2, brain
chr1_+_75351914 15.17 ENSMUST00000087122.12
SPEG complex locus
chr1_+_135764092 15.17 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr3_+_102981352 15.11 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr6_-_88604404 14.69 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr7_-_126399574 14.64 ENSMUST00000106348.8
aldolase A, fructose-bisphosphate
chr9_-_107474221 14.56 ENSMUST00000238519.2
leucine-rich single-pass membrane protein 2
chr5_+_135916847 14.48 ENSMUST00000111155.2
heat shock protein 1
chr7_-_4517608 14.38 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr7_-_4517559 14.28 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr2_+_155453103 14.22 ENSMUST00000092995.6
myosin, heavy chain 7B, cardiac muscle, beta
chr8_+_23548541 13.85 ENSMUST00000173248.8
ankyrin 1, erythroid
chr9_-_79884920 13.67 ENSMUST00000239133.2
filamin A interacting protein 1
chr8_+_120393094 13.43 ENSMUST00000212901.2
ENSMUST00000024107.7
WAP four-disulfide core domain 1
chr5_+_66903174 13.15 ENSMUST00000101164.11
ENSMUST00000238785.2
LIM and calponin homology domains 1
chr16_+_6887689 12.92 ENSMUST00000229741.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_-_154760978 12.86 ENSMUST00000064076.6
TNNI3 interacting kinase
chr9_-_79885063 12.82 ENSMUST00000093811.11
filamin A interacting protein 1
chr6_-_142647985 12.82 ENSMUST00000205202.3
ENSMUST00000073173.12
ENSMUST00000111771.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_+_55825033 12.66 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr11_-_107607343 12.65 ENSMUST00000021065.6
calcium channel, voltage-dependent, gamma subunit 1
chr1_+_135727140 12.31 ENSMUST00000152208.8
ENSMUST00000152075.8
troponin I, skeletal, slow 1
chr14_-_52151537 12.28 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr7_-_4517367 12.06 ENSMUST00000166161.8
troponin T1, skeletal, slow
chr2_-_164675357 12.02 ENSMUST00000042775.5
neuralized E3 ubiquitin protein ligase 2
chr3_+_116356592 11.78 ENSMUST00000029573.8
leucine rich repeat containing 39
chrX_+_55824797 11.76 ENSMUST00000114773.10
four and a half LIM domains 1
chr6_+_42263644 11.75 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr5_+_25964985 11.63 ENSMUST00000128727.8
ENSMUST00000088244.6
ARP3 actin-related protein 3B
chr8_-_62355690 11.55 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr9_-_66421868 11.53 ENSMUST00000056890.10
F-box and leucine-rich repeat protein 22
chr6_+_116627567 11.51 ENSMUST00000067354.10
ENSMUST00000178241.4
DEPP1 autophagy regulator
chr7_-_30754792 11.47 ENSMUST00000206328.2
FXYD domain-containing ion transport regulator 1
chr3_-_20209220 11.45 ENSMUST00000184552.2
glycogenin
chr3_-_20209260 11.33 ENSMUST00000178328.8
glycogenin
chr9_-_65298934 11.25 ENSMUST00000068307.4
kelch repeat and BTB (POZ) domain containing 13
chr1_+_135727228 11.03 ENSMUST00000154463.8
ENSMUST00000139986.8
troponin I, skeletal, slow 1
chr6_-_142647944 11.00 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr14_+_102077937 10.75 ENSMUST00000159026.8
LIM domain only 7
chr2_+_91086299 10.61 ENSMUST00000134699.8
protein kinase C and casein kinase substrate in neurons 3
chr7_-_30755007 10.44 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr18_+_4994600 10.43 ENSMUST00000140448.8
supervillin
chr15_-_58187556 10.28 ENSMUST00000022985.2
kelch-like 38
chr14_-_52151026 10.10 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr16_+_44913974 9.95 ENSMUST00000099498.10
coiled-coil domain containing 80
chr15_+_73620213 9.55 ENSMUST00000053232.8
protein tyrosine phosphatase 4a3
chr14_-_21764638 9.52 ENSMUST00000073870.7
dual specificity phosphatase and pro isomerase domain containing 1
chrX_+_6489313 9.39 ENSMUST00000089520.3
shroom family member 4
chr4_-_41048124 9.33 ENSMUST00000030136.13
aquaporin 7
chr7_+_112341233 9.02 ENSMUST00000164363.9
TEA domain family member 1
chrM_+_5319 8.98 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr6_+_55313409 8.80 ENSMUST00000004774.4
aquaporin 1
chr14_+_102078038 8.80 ENSMUST00000159314.8
LIM domain only 7
chr19_-_24839219 8.74 ENSMUST00000047666.5
phosphoglucomutase 5
chr5_+_66903195 8.55 ENSMUST00000118242.8
LIM and calponin homology domains 1
chr14_+_66581818 8.53 ENSMUST00000118426.8
ENSMUST00000121955.8
ENSMUST00000120229.8
ENSMUST00000134440.2
stathmin-like 4
chr17_+_57556449 8.40 ENSMUST00000224947.2
ENSMUST00000019631.11
ENSMUST00000224885.2
ENSMUST00000224152.2
thyroid hormone receptor interactor 10
chr8_+_46111703 8.26 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr3_-_123029782 8.13 ENSMUST00000106427.8
ENSMUST00000198584.2
synaptopodin 2
chr19_-_40365318 7.62 ENSMUST00000239304.2
sorbin and SH3 domain containing 1
chr1_+_135727571 7.39 ENSMUST00000148201.8
troponin I, skeletal, slow 1
chr10_+_63293284 7.34 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr14_+_47886748 7.16 ENSMUST00000190252.7
ENSMUST00000186466.3
kinectin 1
chr5_+_67125759 7.02 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr3_-_142101418 6.83 ENSMUST00000029941.16
ENSMUST00000058626.9
PDZ and LIM domain 5
chr6_-_119173348 6.72 ENSMUST00000187474.7
ENSMUST00000187940.7
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr15_+_25940859 6.63 ENSMUST00000226750.2
reticulophagy regulator 1
chr8_+_31579499 6.58 ENSMUST00000036631.14
dual specificity phosphatase 26 (putative)
chr10_+_69761597 6.57 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
ankyrin 3, epithelial
chr12_+_69288606 6.57 ENSMUST00000063445.13
kelch domain containing 1
chr11_+_102159558 6.52 ENSMUST00000036467.5
ankyrin repeat and SOCS box-containing 16
chr16_+_5703134 6.18 ENSMUST00000230658.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_101486983 6.13 ENSMUST00000185929.2
ENSMUST00000165052.8
inositol polyphosphate phosphatase-like 1
chr9_-_122016671 5.84 ENSMUST00000216738.2
anoctamin 10
chr4_+_135487016 5.81 ENSMUST00000105854.2
myomesin family, member 3
chr2_+_163535925 5.80 ENSMUST00000109400.3
protein kinase inhibitor, gamma
chr17_+_75742881 5.72 ENSMUST00000164192.9
RAS, guanyl releasing protein 3
chr9_-_118922534 5.57 ENSMUST00000010804.4
phospholipase C, delta 1
chr8_+_31579633 5.55 ENSMUST00000170204.8
dual specificity phosphatase 26 (putative)
chr2_+_120294046 5.50 ENSMUST00000028749.15
ENSMUST00000110721.9
ENSMUST00000239364.2
calpain 3
chr16_-_57575070 5.47 ENSMUST00000089332.5
collagen, type VIII, alpha 1
chr11_+_77353431 5.25 ENSMUST00000130255.2
coronin 6
chr6_+_116627635 5.09 ENSMUST00000204555.2
DEPP1 autophagy regulator
chr3_-_123029745 5.01 ENSMUST00000106426.8
synaptopodin 2
chr14_+_66581745 4.71 ENSMUST00000152093.8
ENSMUST00000074523.13
stathmin-like 4
chr17_-_14914484 4.62 ENSMUST00000170872.3
thrombospondin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
38.3 115.0 GO:0042694 muscle cell fate specification(GO:0042694)
20.4 81.6 GO:0007522 visceral muscle development(GO:0007522)
20.2 141.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
16.9 168.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
13.5 40.5 GO:1903920 positive regulation of actin filament severing(GO:1903920)
13.3 79.9 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
9.8 39.3 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
9.3 37.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
8.6 34.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
8.5 33.8 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
7.2 64.7 GO:0071313 cellular response to caffeine(GO:0071313)
6.8 40.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
6.6 59.7 GO:0015671 oxygen transport(GO:0015671)
6.1 18.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
6.0 18.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
5.1 20.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
4.6 41.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
4.4 22.0 GO:0070543 response to linoleic acid(GO:0070543)
4.0 15.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
3.8 15.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.7 30.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
3.7 41.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
3.7 22.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.7 58.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.6 18.1 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
3.3 29.7 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
3.2 216.5 GO:0045214 sarcomere organization(GO:0045214)
3.1 24.9 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
3.1 31.0 GO:0032264 IMP salvage(GO:0032264)
2.9 132.3 GO:0003009 skeletal muscle contraction(GO:0003009)
2.8 16.7 GO:0006172 ADP biosynthetic process(GO:0006172)
2.7 48.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.7 18.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
2.4 12.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.4 63.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
2.3 30.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
2.1 48.5 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
2.0 21.9 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
1.8 12.6 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
1.7 17.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
1.7 5.1 GO:1904635 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
1.6 43.8 GO:0030239 myofibril assembly(GO:0030239)
1.5 22.9 GO:0014850 response to muscle activity(GO:0014850)
1.5 72.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
1.4 43.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
1.4 34.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
1.4 16.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.2 57.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.2 10.9 GO:0061709 reticulophagy(GO:0061709)
1.2 8.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.1 9.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
1.1 19.1 GO:0014823 response to activity(GO:0014823)
1.1 28.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.1 16.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
1.1 29.5 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
1.0 20.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
1.0 19.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.0 36.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.9 13.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.9 35.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.9 16.9 GO:0002024 diet induced thermogenesis(GO:0002024)
0.8 21.0 GO:0008210 estrogen metabolic process(GO:0008210)
0.8 5.6 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.8 81.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.8 77.5 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.8 69.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.7 9.5 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.7 58.8 GO:0006096 glycolytic process(GO:0006096)
0.7 44.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.7 3.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.7 5.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 24.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 42.1 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.6 3.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.6 11.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.5 2.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.5 1.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.5 1.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.4 20.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 2.8 GO:0001778 plasma membrane repair(GO:0001778)
0.4 2.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 1.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.4 3.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 2.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.3 3.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 5.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 13.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 16.7 GO:0045445 myoblast differentiation(GO:0045445)
0.3 2.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 59.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 1.1 GO:1903525 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.3 0.8 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 13.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 36.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 28.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 14.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 11.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 13.4 GO:0061045 negative regulation of wound healing(GO:0061045)
0.2 18.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 35.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.2 1.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 2.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 5.3 GO:0051642 centrosome localization(GO:0051642)
0.1 17.2 GO:0003012 muscle system process(GO:0003012)
0.1 2.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 1.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 17.7 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 5.5 GO:0048593 camera-type eye morphogenesis(GO:0048593)
0.0 3.2 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
33.1 99.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
27.9 83.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
23.9 95.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
16.2 48.5 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
11.9 154.1 GO:0005861 troponin complex(GO:0005861)
10.5 252.4 GO:0005859 muscle myosin complex(GO:0005859)
9.7 174.1 GO:0097512 cardiac myofibril(GO:0097512)
5.7 79.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
4.9 39.4 GO:0031430 M band(GO:0031430)
4.4 8.8 GO:0032127 dense core granule membrane(GO:0032127)
4.0 12.0 GO:0005927 muscle tendon junction(GO:0005927)
3.8 26.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
3.7 48.6 GO:0005916 fascia adherens(GO:0005916)
3.6 32.8 GO:0016012 sarcoglycan complex(GO:0016012)
3.4 24.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
3.2 762.0 GO:0031674 I band(GO:0031674)
3.1 9.4 GO:0016460 myosin II complex(GO:0016460)
3.1 58.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
2.7 24.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
2.6 39.3 GO:0070852 cell body fiber(GO:0070852)
2.3 9.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.7 19.1 GO:0032982 myosin filament(GO:0032982)
1.7 5.1 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
1.7 18.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.6 29.5 GO:0032593 insulin-responsive compartment(GO:0032593)
1.3 7.6 GO:0005899 insulin receptor complex(GO:0005899)
1.2 16.7 GO:0001520 outer dense fiber(GO:0001520)
1.2 107.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.1 119.4 GO:0030016 myofibril(GO:0030016)
0.9 17.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.8 68.8 GO:0034707 chloride channel complex(GO:0034707)
0.7 61.0 GO:0016528 sarcoplasm(GO:0016528)
0.6 11.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.6 18.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 2.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 60.1 GO:0042383 sarcolemma(GO:0042383)
0.4 113.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.3 12.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 5.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 11.6 GO:0002102 podosome(GO:0002102)
0.2 6.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 40.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 4.6 GO:0031091 platelet alpha granule(GO:0031091)
0.2 2.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 37.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 1.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 15.4 GO:0043195 terminal bouton(GO:0043195)
0.1 32.8 GO:0070382 exocytic vesicle(GO:0070382)
0.1 15.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 18.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 16.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 14.7 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 6.1 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
26.4 131.9 GO:0051373 FATZ binding(GO:0051373)
15.5 108.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
13.1 39.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
12.1 48.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
11.1 331.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
10.1 40.5 GO:0031433 telethonin binding(GO:0031433)
9.7 96.6 GO:0031014 troponin T binding(GO:0031014)
8.1 24.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
7.1 42.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
6.8 20.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
6.8 33.8 GO:1904288 BAT3 complex binding(GO:1904288)
6.6 59.7 GO:0005344 oxygen transporter activity(GO:0005344)
5.9 59.3 GO:0070538 oleic acid binding(GO:0070538)
5.9 29.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
5.7 79.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
5.6 28.0 GO:0031013 troponin I binding(GO:0031013)
5.2 72.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
5.0 65.4 GO:0031432 titin binding(GO:0031432)
4.8 48.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
4.0 36.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
3.8 26.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
3.2 158.2 GO:0003785 actin monomer binding(GO:0003785)
3.1 31.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.6 18.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
2.1 22.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
2.0 58.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.0 12.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.0 30.3 GO:0005523 tropomyosin binding(GO:0005523)
1.9 17.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.9 41.3 GO:0031005 filamin binding(GO:0031005)
1.8 16.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.7 41.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.7 21.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.7 105.8 GO:0042805 actinin binding(GO:0042805)
1.5 8.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.4 13.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.4 30.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.2 16.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.9 15.9 GO:0043495 protein anchor(GO:0043495)
0.7 29.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.7 43.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 16.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 53.7 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.7 7.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6 34.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.6 1.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.6 64.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 8.7 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.5 27.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.5 307.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.4 29.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 35.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 2.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.4 44.6 GO:0005254 chloride channel activity(GO:0005254)
0.4 2.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.4 88.4 GO:0044325 ion channel binding(GO:0044325)
0.4 9.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.3 190.0 GO:0003779 actin binding(GO:0003779)
0.3 9.9 GO:0001968 fibronectin binding(GO:0001968)
0.3 175.3 GO:0005509 calcium ion binding(GO:0005509)
0.2 5.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 4.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 9.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 9.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 5.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 22.0 GO:0030674 protein binding, bridging(GO:0030674)
0.1 2.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 31.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 11.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 3.9 GO:0008083 growth factor activity(GO:0008083)
0.0 1.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 3.7 GO:0015631 tubulin binding(GO:0015631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 115.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.4 54.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.9 29.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 59.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.4 27.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 42.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 13.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 14.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 5.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 5.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 10.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 6.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 610.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
3.6 75.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
2.7 37.3 REACTOME DEFENSINS Genes involved in Defensins
2.6 127.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.7 29.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.5 42.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.3 18.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.2 31.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.2 20.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.0 16.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.9 16.2 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.6 22.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.6 59.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.5 16.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 119.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.4 6.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.4 29.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 5.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 12.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 13.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 10.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 10.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 3.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway