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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Mef2d_Mef2a

Z-value: 6.16

Motif logo

Transcription factors associated with Mef2d_Mef2a

Gene Symbol Gene ID Gene Info
ENSMUSG00000001419.18 Mef2d
ENSMUSG00000030557.18 Mef2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2dmm39_v1_chr3_+_88049875_880498920.449.6e-05Click!
Mef2amm39_v1_chr7_-_66915756_669159100.431.9e-04Click!

Activity profile of Mef2d_Mef2a motif

Sorted Z-values of Mef2d_Mef2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2d_Mef2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_98274637 144.67 ENSMUST00000008021.3
titin-cap
chr10_+_32959472 111.26 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr7_-_127805518 91.35 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr2_+_67276338 81.52 ENSMUST00000239060.2
ENSMUST00000028410.4
ENSMUST00000112347.8
ENSMUST00000238878.2
xin actin-binding repeat containing 2
chr8_+_15107646 80.28 ENSMUST00000033842.4
myomesin 2
chr1_-_66974492 79.41 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr6_-_71239216 78.62 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr1_-_66974694 76.14 ENSMUST00000186202.7
myosin, light polypeptide 1
chr5_+_122239007 72.26 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chrX_+_156481906 71.96 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr19_-_56378459 71.45 ENSMUST00000040711.15
ENSMUST00000095947.11
ENSMUST00000073536.13
nebulin-related anchoring protein
chr5_+_122239030 69.52 ENSMUST00000139213.8
ENSMUST00000111751.8
ENSMUST00000155612.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr14_-_34310637 68.91 ENSMUST00000227819.2
LIM domain binding 3
chr6_-_14755249 68.81 ENSMUST00000045096.6
protein phosphatase 1, regulatory subunit 3A
chr11_-_120538928 67.29 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr19_-_56378309 67.09 ENSMUST00000166203.2
ENSMUST00000167239.8
nebulin-related anchoring protein
chr11_+_67689094 66.52 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr1_+_40844739 65.90 ENSMUST00000114765.4
transmembrane protein 182
chr14_-_34310602 65.66 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr3_-_122828592 62.39 ENSMUST00000029761.14
myozenin 2
chr14_-_20718337 62.09 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr11_-_94867153 60.69 ENSMUST00000103162.8
ENSMUST00000166320.8
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chrX_+_156482116 58.90 ENSMUST00000112521.8
small muscle protein, X-linked
chr11_-_69838971 56.93 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr5_-_24745436 55.44 ENSMUST00000048302.13
ENSMUST00000119657.2
ankyrin repeat and SOCS box-containing 10
chr13_-_113800172 55.14 ENSMUST00000054650.5
heat shock protein 3
chr7_+_80707328 53.91 ENSMUST00000107348.2
alpha-kinase 3
chr14_-_34310438 52.88 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr14_+_55813074 52.65 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chrX_+_163221035 50.95 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr4_+_156300325 50.73 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr15_-_76906832 49.21 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr15_-_89310060 49.11 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr4_+_46039202 48.38 ENSMUST00000156200.8
tropomodulin 1
chr7_+_141995545 48.15 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr7_-_81216687 48.13 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr3_+_102981326 47.10 ENSMUST00000090715.13
ENSMUST00000155034.6
adenosine monophosphate deaminase 1
chr1_-_66984178 47.04 ENSMUST00000027151.12
myosin, light polypeptide 1
chr3_-_142101339 46.33 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr1_-_66984521 46.21 ENSMUST00000160100.2
myosin, light polypeptide 1
chr6_+_42263609 45.70 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr9_-_119852624 44.94 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chr3_+_102981352 43.15 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr7_-_126399208 42.74 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr1_-_172047282 42.55 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr12_+_52746158 42.20 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr2_+_32515442 40.81 ENSMUST00000113277.8
ENSMUST00000195721.6
adenylate kinase 1
chr17_+_71326510 40.63 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr14_-_52151537 40.61 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr9_+_102382949 40.49 ENSMUST00000039390.6
kyphoscoliosis peptidase
chr2_+_90948481 40.35 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr5_-_24745970 39.39 ENSMUST00000117900.8
ankyrin repeat and SOCS box-containing 10
chr5_-_113044216 39.22 ENSMUST00000086617.11
myosin XVIIIb
chr16_-_36810810 39.15 ENSMUST00000075869.13
F-box protein 40
chr17_+_71326542 39.01 ENSMUST00000179759.3
myomesin 1
chr7_+_101750943 38.32 ENSMUST00000033300.4
ADP-ribosyltransferase 1
chrX_-_94521712 38.29 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr4_-_73869071 37.95 ENSMUST00000095023.2
ENSMUST00000030101.4
RIKEN cDNA 2310002L09 gene
chr7_-_126399574 37.73 ENSMUST00000106348.8
aldolase A, fructose-bisphosphate
chr3_+_96432479 37.65 ENSMUST00000049208.11
hemojuvelin BMP co-receptor
chr3_+_32871669 37.36 ENSMUST00000072312.12
ENSMUST00000108228.8
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr8_-_46664321 37.04 ENSMUST00000034049.5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr7_+_127603083 36.84 ENSMUST00000106248.8
tripartite motif-containing 72
chr7_-_126399778 36.24 ENSMUST00000141355.4
aldolase A, fructose-bisphosphate
chr1_+_75351914 35.71 ENSMUST00000087122.12
SPEG complex locus
chr11_-_59029996 35.43 ENSMUST00000219084.3
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr11_+_67128843 35.27 ENSMUST00000018632.11
myosin, heavy polypeptide 4, skeletal muscle
chr13_+_83721696 35.15 ENSMUST00000197146.5
ENSMUST00000185052.6
ENSMUST00000195984.5
myocyte enhancer factor 2C
chr14_-_52151026 35.08 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr11_+_70548022 35.06 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr18_+_61096597 34.86 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr15_-_78090591 34.83 ENSMUST00000120592.2
parvalbumin
chr3_+_101993787 34.80 ENSMUST00000165540.9
ENSMUST00000164123.2
calsequestrin 2
chr4_-_9643636 34.73 ENSMUST00000108333.8
ENSMUST00000108334.8
ENSMUST00000108335.8
ENSMUST00000152526.8
ENSMUST00000103004.10
aspartate-beta-hydroxylase
chrX_+_100492684 34.43 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr2_+_32518402 34.10 ENSMUST00000156578.8
adenylate kinase 1
chr7_-_48497771 34.10 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr9_+_110592709 34.04 ENSMUST00000079784.12
myosin, light polypeptide 3
chr9_+_77543776 33.94 ENSMUST00000057781.8
kelch-like 31
chr1_-_36574801 33.70 ENSMUST00000054665.10
ENSMUST00000194853.3
ankyrin repeat domain 23
chr3_+_101993731 33.66 ENSMUST00000029454.12
calsequestrin 2
chr14_+_26616514 33.58 ENSMUST00000238987.2
ENSMUST00000239004.2
ENSMUST00000165929.4
ENSMUST00000090337.12
ankyrin repeat and SOCS box-containing 14
chr1_-_172125555 33.26 ENSMUST00000085913.11
ENSMUST00000097464.4
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr15_-_89309998 33.03 ENSMUST00000168376.2
carnitine palmitoyltransferase 1b, muscle
chr3_+_116356592 32.92 ENSMUST00000029573.8
leucine rich repeat containing 39
chr10_-_88440869 32.76 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr14_-_32407203 32.59 ENSMUST00000096038.4
RIKEN cDNA 3425401B19 gene
chr13_-_93281065 32.54 ENSMUST00000062122.4
cardiomyopathy associated 5
chr4_+_134042423 32.47 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr18_+_61096660 31.92 ENSMUST00000039904.7
calcium/calmodulin-dependent protein kinase II alpha
chr8_+_55024446 31.86 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr13_-_74512111 31.43 ENSMUST00000022064.5
leucine rich repeat containing 14B
chr19_+_6434416 30.84 ENSMUST00000035269.15
ENSMUST00000113483.2
muscle glycogen phosphorylase
chr16_-_4340920 30.63 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chr9_+_121606750 30.43 ENSMUST00000098272.4
kelch-like 40
chr11_+_82802079 30.33 ENSMUST00000018989.14
ENSMUST00000164945.3
unc-45 myosin chaperone B
chr11_+_70548513 30.33 ENSMUST00000134087.8
enolase 3, beta muscle
chr9_-_101076198 30.26 ENSMUST00000066773.9
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_67090878 30.04 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr16_+_32090286 29.97 ENSMUST00000093183.5
single-pass membrane protein with coiled-coil domains 1
chr7_+_141996067 29.89 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr6_+_42263644 29.56 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr2_+_69500444 29.54 ENSMUST00000100050.4
kelch-like 41
chr13_-_32960379 29.34 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr13_-_32967937 28.89 ENSMUST00000238977.3
myosin light chain kinase family, member 4
chr2_-_25359752 28.02 ENSMUST00000114259.3
ENSMUST00000015234.13
prostaglandin D2 synthase (brain)
chr10_-_88440996 27.54 ENSMUST00000121629.8
myosin binding protein C, slow-type
chr14_-_21764638 27.10 ENSMUST00000073870.7
dual specificity phosphatase and pro isomerase domain containing 1
chr14_-_55204092 26.70 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr14_-_20714634 26.48 ENSMUST00000119483.2
synaptopodin 2-like
chr2_+_120294046 26.43 ENSMUST00000028749.15
ENSMUST00000110721.9
ENSMUST00000239364.2
calpain 3
chr2_-_25360043 26.39 ENSMUST00000114251.8
prostaglandin D2 synthase (brain)
chr14_-_55204054 26.38 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr3_+_137770813 26.30 ENSMUST00000163080.3
RIKEN cDNA 1110002E22 gene
chr14_-_51134930 26.24 ENSMUST00000227271.2
kelch-like 33
chr10_-_81037878 25.82 ENSMUST00000005069.8
nicotinamide riboside kinase 2
chr17_-_48739874 25.63 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_-_76812799 24.98 ENSMUST00000011934.13
ENSMUST00000099981.10
ENSMUST00000099980.10
ENSMUST00000111882.9
ENSMUST00000140091.8
titin
chr15_+_73620213 24.33 ENSMUST00000053232.8
protein tyrosine phosphatase 4a3
chr16_+_6887689 24.09 ENSMUST00000229741.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_112586501 23.38 ENSMUST00000180015.9
adenylosuccinate synthetase like 1
chr3_+_19698631 22.97 ENSMUST00000029139.9
tripartite motif-containing 55
chr2_+_3514071 22.92 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr11_+_102159558 22.59 ENSMUST00000036467.5
ankyrin repeat and SOCS box-containing 16
chr6_-_55109826 22.38 ENSMUST00000164012.3
ENSMUST00000212633.2
corticotropin releasing hormone receptor 2
chr7_+_142052569 22.32 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr14_-_51134906 21.43 ENSMUST00000170855.2
kelch-like 33
chr1_-_39844467 21.42 ENSMUST00000171319.4
predicted gene 3646
chr6_-_142647985 21.35 ENSMUST00000205202.3
ENSMUST00000073173.12
ENSMUST00000111771.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_134121170 21.27 ENSMUST00000038445.13
ENSMUST00000191577.2
myosin binding protein H
chr10_+_127337541 21.26 ENSMUST00000160019.8
ENSMUST00000160610.2
ENSMUST00000035839.3
SH3 and cysteine rich domain 3
chr3_-_20209220 21.20 ENSMUST00000184552.2
glycogenin
chr18_-_39062201 21.06 ENSMUST00000134864.2
fibroblast growth factor 1
chr1_-_134162231 20.99 ENSMUST00000169927.2
adenosine A1 receptor
chr8_+_23548541 20.93 ENSMUST00000173248.8
ankyrin 1, erythroid
chr9_-_77255099 20.62 ENSMUST00000184138.8
ENSMUST00000184006.8
ENSMUST00000185144.8
ENSMUST00000034910.16
muscular LMNA-interacting protein
chr3_-_20209260 20.50 ENSMUST00000178328.8
glycogenin
chr6_-_55109960 20.34 ENSMUST00000003568.15
corticotropin releasing hormone receptor 2
chr7_-_101749433 19.48 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr5_+_92534738 19.40 ENSMUST00000128246.8
ADP-ribosyltransferase 3
chr9_-_77255069 19.22 ENSMUST00000184848.8
ENSMUST00000184415.8
muscular LMNA-interacting protein
chr6_-_34294377 19.18 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr2_+_91086489 19.12 ENSMUST00000154959.8
ENSMUST00000059566.11
protein kinase C and casein kinase substrate in neurons 3
chrX_-_58613428 19.09 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chr11_+_110956980 19.07 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_-_74788013 18.61 ENSMUST00000188073.7
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr12_+_37158532 18.60 ENSMUST00000041183.7
mesenchyme homeobox 2
chr12_+_69288606 18.50 ENSMUST00000063445.13
kelch domain containing 1
chr6_-_142647944 18.46 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_-_88604404 18.00 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr3_-_63391300 17.72 ENSMUST00000192926.2
small transmembrane regulator of ion transport 1
chrX_+_72818003 17.64 ENSMUST00000002081.6
serine/arginine-rich protein specific kinase 3
chr14_-_55204383 17.50 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr9_-_107474221 17.27 ENSMUST00000238519.2
leucine-rich single-pass membrane protein 2
chr1_-_89942299 16.94 ENSMUST00000086882.8
ENSMUST00000097656.10
ankyrin repeat and SOCS box-containing 18
chr3_-_123029782 16.61 ENSMUST00000106427.8
ENSMUST00000198584.2
synaptopodin 2
chr3_+_95071617 16.58 ENSMUST00000168321.8
ENSMUST00000107217.6
ENSMUST00000202315.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr9_-_65298934 16.01 ENSMUST00000068307.4
kelch repeat and BTB (POZ) domain containing 13
chr5_-_24806960 15.97 ENSMUST00000030791.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chrX_-_58612709 15.90 ENSMUST00000124402.2
fibroblast growth factor 13
chr14_-_55204023 15.71 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr5_+_25964985 15.35 ENSMUST00000128727.8
ENSMUST00000088244.6
ARP3 actin-related protein 3B
chr15_+_101152078 15.14 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr9_-_77255171 15.12 ENSMUST00000185039.8
muscular LMNA-interacting protein
chr14_-_36641470 15.05 ENSMUST00000182042.2
coiled-coil serine rich 2
chr3_+_68491487 14.91 ENSMUST00000182997.3
schwannomin interacting protein 1
chr14_+_47886748 14.66 ENSMUST00000190252.7
ENSMUST00000186466.3
kinectin 1
chrX_-_101687813 14.63 ENSMUST00000052012.14
ENSMUST00000043596.12
ENSMUST00000119229.8
ENSMUST00000122022.8
ENSMUST00000120270.8
ENSMUST00000113611.3
phosphorylase kinase alpha 1
chr15_-_58187556 14.52 ENSMUST00000022985.2
kelch-like 38
chr16_-_28571820 14.51 ENSMUST00000232352.2
fibroblast growth factor 12
chr10_-_107330580 14.27 ENSMUST00000044210.5
myogenic factor 6
chr7_-_4517559 14.21 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr11_+_73051228 14.17 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_4517608 13.99 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr7_-_30755007 13.95 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr14_-_36641270 13.79 ENSMUST00000182797.8
coiled-coil serine rich 2
chr19_+_47217279 13.67 ENSMUST00000111807.5
neuralized E3 ubiquitin protein ligase 1A
chr13_-_63006176 13.53 ENSMUST00000021907.9
fructose bisphosphatase 2
chr4_+_99812912 13.26 ENSMUST00000102783.5
phosphoglucomutase 1
chr7_-_30754792 13.11 ENSMUST00000206328.2
FXYD domain-containing ion transport regulator 1
chr1_+_135727140 12.98 ENSMUST00000152208.8
ENSMUST00000152075.8
troponin I, skeletal, slow 1
chr11_-_107607343 12.70 ENSMUST00000021065.6
calcium channel, voltage-dependent, gamma subunit 1
chr11_+_67167950 12.15 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr1_+_135727228 12.00 ENSMUST00000154463.8
ENSMUST00000139986.8
troponin I, skeletal, slow 1
chr8_-_84301386 11.92 ENSMUST00000238861.2
trans-2,3-enoyl-CoA reductase
chr8_+_31579499 11.67 ENSMUST00000036631.14
dual specificity phosphatase 26 (putative)
chr1_+_135764092 11.51 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr4_-_134099840 11.35 ENSMUST00000030643.3
exostosin-like glycosyltransferase 1
chr4_+_135975243 11.33 ENSMUST00000102533.11
ENSMUST00000143942.2
transcription elongation factor A (SII), 3
chr4_-_126150066 11.26 ENSMUST00000122129.8
ENSMUST00000061143.15
ENSMUST00000106132.3
MAP7 domain containing 1
chr1_-_43235914 11.25 ENSMUST00000187357.2
four and a half LIM domains 2
chr7_-_4517367 11.24 ENSMUST00000166161.8
troponin T1, skeletal, slow
chr1_+_75336965 11.03 ENSMUST00000027409.10
desmin
chr15_+_94527117 11.00 ENSMUST00000080141.6
transmembrane protein 117
chr3_-_123029745 10.74 ENSMUST00000106426.8
synaptopodin 2
chr7_-_80020830 10.64 ENSMUST00000205436.2
ENSMUST00000098346.5
mannosidase 2, alpha 2
chr1_-_163552693 10.59 ENSMUST00000159679.8
methyltransferase like 11B
chr8_+_31579633 10.53 ENSMUST00000170204.8
dual specificity phosphatase 26 (putative)
chr6_+_58808733 10.50 ENSMUST00000126292.8
ENSMUST00000031823.12
hect domain and RLD 3
chr18_-_39062514 10.48 ENSMUST00000235922.2
fibroblast growth factor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
47.3 141.8 GO:0042694 muscle cell fate specification(GO:0042694)
31.1 218.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
28.2 281.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
21.6 86.3 GO:0007522 visceral muscle development(GO:0007522)
19.2 153.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
12.6 75.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
12.5 74.9 GO:0006172 ADP biosynthetic process(GO:0006172)
11.6 34.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
11.4 68.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
11.4 34.1 GO:1903920 positive regulation of actin filament severing(GO:1903920)
10.8 32.5 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
10.7 42.7 GO:2000292 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
10.6 42.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
10.2 30.6 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
9.3 37.4 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
9.3 37.0 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
9.1 54.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
9.0 90.3 GO:0032264 IMP salvage(GO:0032264)
8.3 33.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
7.2 130.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
7.0 21.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
6.6 26.4 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
6.6 52.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
6.6 39.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
6.4 19.2 GO:0090420 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
6.4 19.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
5.8 23.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
5.8 75.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
5.7 91.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
5.5 49.2 GO:0015671 oxygen transport(GO:0015671)
5.4 32.5 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
5.3 355.5 GO:0045214 sarcomere organization(GO:0045214)
5.1 15.3 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
5.0 35.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
4.8 66.8 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
4.5 31.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
4.4 22.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
4.3 30.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
4.1 37.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
4.0 167.6 GO:0003009 skeletal muscle contraction(GO:0003009)
3.9 11.8 GO:2000184 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
3.9 50.7 GO:0014850 response to muscle activity(GO:0014850)
3.8 30.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
3.8 11.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.6 18.0 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
3.3 39.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
3.0 9.0 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
3.0 27.1 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
2.9 14.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
2.7 75.8 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
2.7 18.6 GO:0001757 somite specification(GO:0001757)
2.4 14.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
2.4 411.4 GO:0006941 striated muscle contraction(GO:0006941)
2.3 16.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
2.1 78.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
2.1 12.7 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
2.1 14.7 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
2.1 52.3 GO:0030239 myofibril assembly(GO:0030239)
2.1 35.3 GO:0014823 response to activity(GO:0014823)
2.0 56.9 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
2.0 6.0 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
2.0 25.6 GO:0016554 cytidine to uridine editing(GO:0016554)
2.0 27.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.9 40.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.9 7.6 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
1.9 147.9 GO:0055013 cardiac muscle cell development(GO:0055013)
1.7 32.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.6 77.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
1.6 14.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
1.5 30.8 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
1.5 7.6 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
1.5 16.5 GO:0006013 mannose metabolic process(GO:0006013)
1.4 81.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
1.4 7.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
1.3 6.6 GO:0060023 soft palate development(GO:0060023)
1.3 129.1 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
1.3 5.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.2 3.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.1 28.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.1 25.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.1 88.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
1.1 16.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.1 10.0 GO:0015669 gas transport(GO:0015669) carbon dioxide transport(GO:0015670)
1.1 9.9 GO:0061709 reticulophagy(GO:0061709)
1.1 13.7 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.0 4.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.0 82.1 GO:0015909 long-chain fatty acid transport(GO:0015909)
1.0 3.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.9 2.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.9 7.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.8 20.2 GO:0042118 endothelial cell activation(GO:0042118)
0.8 20.1 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.8 3.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.7 7.0 GO:2000741 negative regulation of cardiac muscle cell differentiation(GO:2000726) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.7 18.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.6 2.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 41.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.6 19.2 GO:0010107 potassium ion import(GO:0010107)
0.6 4.8 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 14.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.6 10.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 5.9 GO:0070842 aggresome assembly(GO:0070842)
0.5 20.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.5 9.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.4 34.1 GO:0006096 glycolytic process(GO:0006096)
0.4 0.8 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.4 4.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.4 5.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.4 77.5 GO:0003012 muscle system process(GO:0003012)
0.4 56.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.4 11.0 GO:0045109 intermediate filament organization(GO:0045109)
0.4 1.4 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.4 3.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.3 3.1 GO:0001778 plasma membrane repair(GO:0001778)
0.3 8.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.3 12.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 9.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 10.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3 5.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 4.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 15.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.3 7.4 GO:0045475 locomotor rhythm(GO:0045475)
0.3 3.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 4.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 1.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.3 10.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.3 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.2 3.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 3.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 41.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 26.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 4.0 GO:0035428 hexose transmembrane transport(GO:0035428)
0.2 3.2 GO:0051601 exocyst localization(GO:0051601)
0.2 9.5 GO:0060612 adipose tissue development(GO:0060612)
0.2 8.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 0.9 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 4.3 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.9 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 1.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 3.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 9.1 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 2.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 10.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 6.2 GO:0009268 response to pH(GO:0009268)
0.1 74.1 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.1 3.7 GO:0045445 myoblast differentiation(GO:0045445)
0.1 23.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 6.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 11.7 GO:0006006 glucose metabolic process(GO:0006006)
0.1 4.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 4.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 2.7 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 6.2 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 8.5 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 6.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.3 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
38.4 153.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
37.0 111.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
34.9 279.2 GO:0005927 muscle tendon junction(GO:0005927)
25.3 75.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
22.2 66.5 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
16.7 66.8 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
16.0 382.8 GO:0005859 muscle myosin complex(GO:0005859)
13.3 173.0 GO:0005861 troponin complex(GO:0005861)
10.4 187.7 GO:0097512 cardiac myofibril(GO:0097512)
6.7 60.7 GO:0016012 sarcoglycan complex(GO:0016012)
5.9 29.5 GO:0031430 M band(GO:0031430)
5.4 74.9 GO:0001520 outer dense fiber(GO:0001520)
5.2 99.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
4.9 53.9 GO:0005916 fascia adherens(GO:0005916)
4.5 1090.6 GO:0031674 I band(GO:0031674)
4.4 39.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
4.3 47.4 GO:0032982 myosin filament(GO:0032982)
4.1 57.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.9 11.8 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
3.8 19.2 GO:0097454 Schwann cell microvillus(GO:0097454)
3.4 371.2 GO:0030016 myofibril(GO:0030016)
3.3 33.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
3.2 34.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
3.0 57.2 GO:0032593 insulin-responsive compartment(GO:0032593)
2.8 42.7 GO:0070852 cell body fiber(GO:0070852)
2.1 14.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.6 4.7 GO:0016460 myosin II complex(GO:0016460)
1.5 8.8 GO:0005899 insulin receptor complex(GO:0005899)
1.3 107.7 GO:0034707 chloride channel complex(GO:0034707)
1.3 123.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.2 70.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
1.0 21.0 GO:0032279 asymmetric synapse(GO:0032279)
0.9 2.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.9 30.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.9 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.8 23.6 GO:0043292 contractile fiber(GO:0043292)
0.8 4.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.8 15.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.7 14.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.7 26.4 GO:0014704 intercalated disc(GO:0014704)
0.6 16.0 GO:0071564 npBAF complex(GO:0071564)
0.6 139.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.6 18.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 167.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.5 10.6 GO:0005922 connexon complex(GO:0005922)
0.4 82.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 7.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.4 55.0 GO:0016605 PML body(GO:0016605)
0.4 41.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 13.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 1.0 GO:0090537 CERF complex(GO:0090537)
0.3 43.8 GO:0042383 sarcolemma(GO:0042383)
0.3 3.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 6.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 6.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 1.2 GO:0044305 calyx of Held(GO:0044305) presynaptic active zone cytoplasmic component(GO:0098831)
0.2 23.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 25.2 GO:0005604 basement membrane(GO:0005604)
0.1 5.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 3.2 GO:0000145 exocyst(GO:0000145)
0.1 8.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 11.0 GO:0043195 terminal bouton(GO:0043195)
0.1 6.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 8.5 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0016592 mediator complex(GO:0016592)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 5.3 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
41.4 207.1 GO:0051373 FATZ binding(GO:0051373)
22.0 660.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
15.5 108.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
14.2 42.7 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
13.7 82.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
13.6 54.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
13.2 39.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
11.7 117.5 GO:0031014 troponin T binding(GO:0031014)
11.7 116.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
11.4 56.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
9.8 128.0 GO:0031432 titin binding(GO:0031432)
9.0 90.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
8.6 25.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
8.5 34.1 GO:0031433 telethonin binding(GO:0031433)
7.8 23.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
7.7 30.8 GO:0008184 glycogen phosphorylase activity(GO:0008184)
7.5 37.4 GO:1904288 BAT3 complex binding(GO:1904288)
6.5 58.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
5.5 77.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
5.5 16.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
5.5 49.2 GO:0005344 oxygen transporter activity(GO:0005344)
5.4 74.9 GO:0004017 adenylate kinase activity(GO:0004017)
4.2 66.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
4.1 57.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
4.0 20.2 GO:0031013 troponin I binding(GO:0031013)
3.8 41.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
3.8 11.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
3.7 22.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
3.5 175.8 GO:0003785 actin monomer binding(GO:0003785)
3.4 99.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.4 75.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
3.4 13.7 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
3.4 37.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
3.3 49.0 GO:0005523 tropomyosin binding(GO:0005523)
2.8 25.6 GO:0004126 cytidine deaminase activity(GO:0004126)
2.8 66.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
2.8 33.3 GO:1990239 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
2.7 19.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.6 15.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
2.5 159.9 GO:0042805 actinin binding(GO:0042805)
2.3 42.2 GO:0043495 protein anchor(GO:0043495)
2.3 21.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
2.2 13.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
2.2 28.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
2.1 44.9 GO:0031005 filamin binding(GO:0031005)
2.1 20.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
2.1 14.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.6 31.5 GO:0044548 S100 protein binding(GO:0044548)
1.6 14.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.5 40.9 GO:0003680 AT DNA binding(GO:0003680)
1.5 7.5 GO:0015254 glycerol channel activity(GO:0015254)
1.4 19.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.4 1.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.3 20.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.2 78.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
1.1 9.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.9 18.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.9 4.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.9 6.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.8 13.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.8 8.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.8 68.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.8 18.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.8 10.1 GO:0070097 delta-catenin binding(GO:0070097)
0.8 48.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 5.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 1.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.7 27.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.7 4.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.6 438.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.6 13.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 65.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 30.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.6 10.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.6 4.4 GO:0001515 opioid peptide activity(GO:0001515)
0.5 27.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 9.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 4.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 5.7 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.5 362.6 GO:0005509 calcium ion binding(GO:0005509)
0.5 6.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.5 94.7 GO:0044325 ion channel binding(GO:0044325)
0.4 6.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4 14.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 42.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 9.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 4.5 GO:0017166 vinculin binding(GO:0017166)
0.4 6.2 GO:0005243 gap junction channel activity(GO:0005243)
0.3 7.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 39.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 43.8 GO:0030674 protein binding, bridging(GO:0030674)
0.3 13.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 20.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.3 131.2 GO:0003779 actin binding(GO:0003779)
0.2 3.6 GO:0016208 AMP binding(GO:0016208)
0.2 38.6 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 22.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 5.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 10.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 4.2 GO:0030275 LRR domain binding(GO:0030275)
0.2 4.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 2.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 4.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 9.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 78.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 3.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.1 28.8 GO:0008017 microtubule binding(GO:0008017)
0.1 3.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 6.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0031402 sodium ion binding(GO:0031402)
0.0 3.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 4.6 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 141.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
2.7 105.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.3 66.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.0 103.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
1.0 74.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.0 15.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 58.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.7 54.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 24.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 11.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 39.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 17.7 PID INSULIN PATHWAY Insulin Pathway
0.3 29.0 PID FGF PATHWAY FGF signaling pathway
0.3 16.0 PID LKB1 PATHWAY LKB1 signaling events
0.2 11.0 PID AURORA B PATHWAY Aurora B signaling
0.2 4.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 7.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 14.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 10.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 4.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 19.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 9.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 6.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
14.6 949.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
3.7 182.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
3.6 90.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
3.6 60.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
3.5 100.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
2.8 58.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
2.7 38.3 REACTOME DEFENSINS Genes involved in Defensins
2.3 74.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.2 62.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.7 35.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.4 23.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.4 38.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.0 14.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.0 27.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
1.0 66.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.9 42.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.8 37.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.7 25.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 180.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.6 13.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 7.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 10.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.5 26.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 7.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 35.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 1.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 9.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 4.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 5.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 8.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 9.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 3.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 6.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 4.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 7.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 12.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 12.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 2.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing