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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Meox2

Z-value: 1.03

Motif logo

Transcription factors associated with Meox2

Gene Symbol Gene ID Gene Info
ENSMUSG00000036144.7 Meox2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meox2mm39_v1_chr12_+_37158532_371585450.515.4e-06Click!

Activity profile of Meox2 motif

Sorted Z-values of Meox2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Meox2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_68609426 9.93 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr6_+_68247469 7.22 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr16_-_19079594 6.30 ENSMUST00000103752.3
ENSMUST00000197518.2
immunoglobulin lambda variable 2
chr1_+_174000304 5.86 ENSMUST00000027817.8
spectrin alpha, erythrocytic 1
chr17_-_34506744 5.61 ENSMUST00000174751.2
ENSMUST00000040655.14
histocompatibility 2, class II antigen A, alpha
chr6_+_41511733 4.80 ENSMUST00000103287.2
T cell receptor beta joining 1-4
chr18_+_60936910 4.79 ENSMUST00000097563.9
ENSMUST00000050487.16
ENSMUST00000167610.2
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr6_-_41012435 4.75 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr6_+_41510925 4.72 ENSMUST00000103285.2
T cell receptor beta joining 1-2
chr6_-_69877961 4.64 ENSMUST00000197290.2
immunoglobulin kappa variable 5-39
chr17_+_34457868 4.57 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
histocompatibility 2, O region beta locus
chr6_+_41512010 4.45 ENSMUST00000103288.2
T cell receptor beta joining 1-5
chr6_+_41511248 4.07 ENSMUST00000192366.2
ENSMUST00000103286.2
T cell receptor beta joining 1-3
chr13_-_19491721 4.05 ENSMUST00000103561.3
T cell receptor gamma, constant 2
chr10_-_88518878 3.97 ENSMUST00000004473.15
Spi-C transcription factor (Spi-1/PU.1 related)
chr6_+_68098030 3.92 ENSMUST00000103317.3
immunoglobulin kappa variable 1-117
chr13_+_19398273 3.76 ENSMUST00000103558.3
T cell receptor gamma, constant 1
chr14_-_61495934 3.71 ENSMUST00000077954.13
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr6_+_70584375 3.63 ENSMUST00000197560.2
immunoglobulin kappa variable 3-7
chr11_+_46701619 3.46 ENSMUST00000068877.7
T cell immunoglobulin and mucin domain containing 4
chr6_-_68713748 3.46 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr13_+_19445054 3.38 ENSMUST00000164407.2
ENSMUST00000198163.2
T cell receptor gamma, constant 3
chr14_-_61495832 3.31 ENSMUST00000121148.8
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr12_+_108572015 3.12 ENSMUST00000109854.9
Ena-vasodilator stimulated phosphoprotein
chr1_-_194859015 3.10 ENSMUST00000082321.9
ENSMUST00000195120.6
complement receptor 2
chr6_+_68196928 3.10 ENSMUST00000103318.6
ENSMUST00000103319.3
immunoglobulin kappa variable 2-112
chr12_-_114621406 3.04 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr4_+_114914880 2.99 ENSMUST00000161601.8
T cell acute lymphocytic leukemia 1
chr7_-_3901119 2.88 ENSMUST00000070639.8
predicted gene 14548
chr1_-_194858918 2.84 ENSMUST00000210219.2
ENSMUST00000193801.2
complement receptor 2
chr6_+_41510788 2.80 ENSMUST00000103284.2
T cell receptor beta joining 1-1
chr3_-_59009231 2.64 ENSMUST00000085040.5
G protein-coupled receptor 171
chr10_-_81335966 2.61 ENSMUST00000053646.7
sphingosine-1-phosphate receptor 4
chr5_-_105198913 2.60 ENSMUST00000112718.5
guanylate-binding protein 8
chr16_+_57369595 2.50 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr5_-_108943211 2.46 ENSMUST00000004943.2
transmembrane p24 trafficking protein 11
chr14_-_20706556 2.44 ENSMUST00000090469.8
myozenin 1
chr17_+_87270504 2.24 ENSMUST00000024956.15
ras homolog family member Q
chr7_-_30523191 2.23 ENSMUST00000053156.10
free fatty acid receptor 2
chrX_+_56257374 2.22 ENSMUST00000033466.2
CD40 ligand
chr15_+_103148824 2.20 ENSMUST00000036004.16
ENSMUST00000087351.9
ENSMUST00000231141.2
heterogeneous nuclear ribonucleoprotein A1
chr18_-_43925932 2.19 ENSMUST00000237926.2
ENSMUST00000096570.4
predicted gene 94
chr6_-_78355834 2.18 ENSMUST00000089667.8
ENSMUST00000167492.4
regenerating islet-derived 3 delta
chr6_-_69282389 2.17 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr1_-_69726384 2.11 ENSMUST00000187184.7
IKAROS family zinc finger 2
chr17_+_75312520 2.10 ENSMUST00000234490.2
ENSMUST00000001927.12
latent transforming growth factor beta binding protein 1
chr15_-_99549457 2.10 ENSMUST00000171908.2
ENSMUST00000171702.8
ENSMUST00000109581.3
ENSMUST00000169810.8
ENSMUST00000023756.12
Rac GTPase-activating protein 1
chr14_-_20546848 2.07 ENSMUST00000022353.5
MSS51 mitochondrial translational activator
chr6_+_41279199 2.06 ENSMUST00000031913.5
trypsin 4
chr1_-_173301492 1.96 ENSMUST00000169797.2
interferon activated gene 206
chr6_+_70495224 1.96 ENSMUST00000103396.2
immunoglobulin kappa variable 3-12
chr4_-_136626073 1.94 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr12_+_117807224 1.94 ENSMUST00000021592.16
cell division cycle associated 7 like
chr4_+_66745803 1.88 ENSMUST00000048096.12
ENSMUST00000107365.3
toll-like receptor 4
chr12_-_114878652 1.83 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr7_+_139827152 1.83 ENSMUST00000164583.8
ENSMUST00000093984.3
scavenger receptor family member expressed on T cells 2
chr12_-_115798038 1.82 ENSMUST00000103544.3
immunoglobulin heavy variable 1-75
chr12_-_114955196 1.82 ENSMUST00000194865.2
immunoglobulin heavy variable 1-47
chr3_-_98247237 1.81 ENSMUST00000065793.12
3-phosphoglycerate dehydrogenase
chr5_-_65090893 1.81 ENSMUST00000197315.5
toll-like receptor 1
chr9_+_72345267 1.79 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr6_-_69477770 1.78 ENSMUST00000197448.2
immunoglobulin kappa variable 4-58
chr7_+_27259895 1.77 ENSMUST00000187032.2
RIKEN cDNA 2310022A10 gene
chr7_+_88079465 1.69 ENSMUST00000107256.4
RAB38, member RAS oncogene family
chr16_-_56688024 1.66 ENSMUST00000232373.2
transmembrane protein 45a
chr8_+_66838927 1.65 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr10_+_102376109 1.61 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr8_+_3410842 1.60 ENSMUST00000238813.2
rho/rac guanine nucleotide exchange factor (GEF) 18
chr13_+_83652352 1.57 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr3_-_154760978 1.54 ENSMUST00000064076.6
TNNI3 interacting kinase
chr7_-_67913949 1.51 ENSMUST00000032770.4
ENSMUST00000207874.2
pyroglutamyl-peptidase I-like
chr15_+_102204691 1.50 ENSMUST00000064924.6
ENSMUST00000230212.2
ENSMUST00000229050.2
ENSMUST00000231104.2
extra spindle pole bodies 1, separase
chr2_+_87696836 1.49 ENSMUST00000213308.3
olfactory receptor 1152
chr4_+_134658209 1.47 ENSMUST00000030622.3
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr2_+_32617671 1.46 ENSMUST00000113242.5
SH2 domain containing 3C
chr1_+_189460461 1.45 ENSMUST00000097442.9
protein tyrosine phosphatase, non-receptor type 14
chr12_-_114451189 1.43 ENSMUST00000103493.3
immunoglobulin heavy variable 1-4
chr17_-_33937565 1.42 ENSMUST00000174040.2
ENSMUST00000173015.8
ENSMUST00000066121.13
ENSMUST00000186022.7
ENSMUST00000173329.8
ENSMUST00000172767.9
membrane associated ring-CH-type finger 2
chr7_-_3828640 1.41 ENSMUST00000189095.7
ENSMUST00000094911.5
ENSMUST00000153846.8
ENSMUST00000108619.8
ENSMUST00000108620.8
predicted gene 15448
chr15_+_100659622 1.41 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr11_-_69556888 1.41 ENSMUST00000108654.3
CD68 antigen
chr3_-_72875187 1.37 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr13_+_28441511 1.36 ENSMUST00000223428.2
ribosomal protein S18, pseudogene 5
chr5_-_147831610 1.34 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
solute carrier family 46, member 3
chr6_+_47897410 1.32 ENSMUST00000009411.9
Zinc finger protein 212
chr1_-_144427302 1.32 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr2_+_103254401 1.31 ENSMUST00000028609.14
E74-like factor 5
chr8_-_125675901 1.31 ENSMUST00000034469.7
egl-9 family hypoxia-inducible factor 1
chr1_-_106980033 1.29 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr16_-_16494269 1.29 ENSMUST00000206365.3
olfactory receptor 19
chr2_-_17465410 1.29 ENSMUST00000145492.2
nebulette
chr14_+_53007210 1.29 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr6_+_67993691 1.29 ENSMUST00000103314.3
immunoglobulin kappa chain variable 1-122
chr3_+_115681486 1.28 ENSMUST00000189799.7
ENSMUST00000200258.2
diphthamide biosynthesis 5
chr2_+_103788321 1.28 ENSMUST00000156813.8
ENSMUST00000170926.8
LIM domain only 2
chr9_-_36637670 1.27 ENSMUST00000172702.9
ENSMUST00000172742.2
checkpoint kinase 1
chr9_+_94551929 1.25 ENSMUST00000033463.10
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_-_71417607 1.25 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr11_+_46345784 1.20 ENSMUST00000109229.2
hepatitis A virus cellular receptor 2
chr13_+_104365880 1.16 ENSMUST00000022227.8
centromere protein K
chr14_+_73376192 1.13 ENSMUST00000171070.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr14_+_54082691 1.11 ENSMUST00000103674.6
T cell receptor alpha variable 19
chr19_-_34143437 1.09 ENSMUST00000025686.9
ankyrin repeat domain 22
chr12_-_55033130 1.09 ENSMUST00000173433.8
ENSMUST00000173803.2
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr13_+_83652280 1.09 ENSMUST00000199450.5
myocyte enhancer factor 2C
chr9_-_36637923 1.08 ENSMUST00000034625.12
checkpoint kinase 1
chr2_+_89821565 1.07 ENSMUST00000111509.3
ENSMUST00000213909.3
olfactory receptor 1261
chr11_+_46345747 1.06 ENSMUST00000020668.15
hepatitis A virus cellular receptor 2
chr10_-_119948890 1.05 ENSMUST00000020449.12
helicase (DNA) B
chr7_-_34012956 1.04 ENSMUST00000108074.8
granule associated Rac and RHOG effector 1
chr3_+_66127330 1.04 ENSMUST00000029421.6
pentraxin related gene
chr4_+_102278715 1.02 ENSMUST00000106904.9
phosphodiesterase 4B, cAMP specific
chr12_-_115825934 1.02 ENSMUST00000198777.2
immunoglobulin heavy variable 1-77
chr14_+_52904815 1.02 ENSMUST00000198058.2
ENSMUST00000103573.3
T cell receptor alpha variable 6-2
chr17_-_40553176 1.01 ENSMUST00000026499.6
cysteine-rich secretory protein 3
chr14_+_53599724 0.99 ENSMUST00000196105.2
T cell receptor alpha variable 13N-4
chr7_-_34012934 0.98 ENSMUST00000206399.2
granule associated Rac and RHOG effector 1
chr6_-_68968278 0.92 ENSMUST00000197966.2
immunoglobulin kappa variable 4-81
chr16_-_58620631 0.91 ENSMUST00000206205.3
olfactory receptor 173
chr16_+_4457805 0.91 ENSMUST00000038770.4
vasorin
chr10_-_51507527 0.89 ENSMUST00000219286.2
ENSMUST00000020062.4
ENSMUST00000218684.2
G protein-coupled receptor, family C, group 6, member A
chr15_-_103148239 0.89 ENSMUST00000118152.8
chromobox 5
chr12_-_115410489 0.89 ENSMUST00000194581.2
immunoglobulin heavy variable 1-62-2
chr9_+_38312994 0.88 ENSMUST00000214648.3
ENSMUST00000056364.3
olfactory receptor 147
chr18_+_75133519 0.88 ENSMUST00000079716.6
ribosomal protein L17
chr2_+_26471062 0.88 ENSMUST00000238951.2
ENSMUST00000166920.10
EGF-like domain 7
chr16_+_33071784 0.87 ENSMUST00000023502.6
sorting nexin 4
chr4_+_103000248 0.86 ENSMUST00000106855.2
MEIR1 treanscription regulator
chr6_-_87815653 0.86 ENSMUST00000204431.2
ENSMUST00000089497.7
ISY1 splicing factor homolog
chr19_+_34078333 0.86 ENSMUST00000025685.8
lipase, family member M
chr4_+_11558905 0.85 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr8_+_112264095 0.85 ENSMUST00000173726.8
ENSMUST00000174454.8
zinc and ring finger 1
chr14_+_53328803 0.84 ENSMUST00000103609.2
T cell receptor alpha variable 7N-4
chr1_-_155910546 0.84 ENSMUST00000169241.8
torsin A interacting protein 1
chr1_+_134333720 0.82 ENSMUST00000173908.8
cytochrome b5 reductase 1
chr11_-_99494134 0.79 ENSMUST00000072306.4
predicted gene 11938
chr10_-_43934774 0.78 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr7_+_45271229 0.75 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr6_+_41928559 0.74 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr10_+_58207229 0.73 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr16_-_56891711 0.72 ENSMUST00000067173.8
ENSMUST00000227043.2
transmembrane protein 45A2
chr2_-_150097511 0.72 ENSMUST00000063463.6
predicted gene 21994
chr15_+_74593041 0.71 ENSMUST00000070923.3
thioesterase superfamily member 6
chr6_-_116561156 0.70 ENSMUST00000061723.6
olfactory receptor 215
chr2_-_85916198 0.70 ENSMUST00000099911.5
olfactory receptor 1037
chr11_-_71092282 0.70 ENSMUST00000108515.9
NLR family, pyrin domain containing 1B
chr1_-_37955569 0.68 ENSMUST00000078307.7
lysozyme G-like 2
chr13_-_23417289 0.67 ENSMUST00000077116.5
vomeronasal 1 receptor 222
chr14_-_55950545 0.66 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr12_-_114815280 0.66 ENSMUST00000103512.3
immunoglobulin heavy variable 1-34
chr14_+_50360643 0.66 ENSMUST00000215317.2
olfactory receptor 727
chr2_+_91376650 0.64 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr8_-_57003828 0.63 ENSMUST00000134162.8
ENSMUST00000140107.8
ENSMUST00000040330.15
ENSMUST00000135337.8
centrosomal protein 44
chr12_-_115019136 0.63 ENSMUST00000103519.2
ENSMUST00000192724.2
immunoglobulin heavy variable 1-49
chr16_+_42727926 0.62 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr4_-_52859227 0.62 ENSMUST00000107670.3
olfactory receptor 273
chr3_+_32490300 0.62 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr6_+_43212512 0.60 ENSMUST00000078057.4
olfactory receptor 47
chr3_+_92874366 0.60 ENSMUST00000098886.5
late cornified envelope 3E
chr3_-_151899470 0.59 ENSMUST00000050073.13
DnaJ heat shock protein family (Hsp40) member B4
chr13_-_97897139 0.59 ENSMUST00000074072.5
ribosomal protein S18, pseudogene 6
chr7_-_89630141 0.58 ENSMUST00000238981.2
ENSMUST00000208977.2
ENSMUST00000107234.3
embryonic ectoderm development
chr4_-_144447974 0.57 ENSMUST00000036876.8
AADACL4 family member 3
chr10_+_25274491 0.57 ENSMUST00000219900.2
erythrocyte membrane protein band 4.1 like 2
chr9_-_20247390 0.56 ENSMUST00000212943.4
ENSMUST00000086473.4
olfactory receptor 18
chr8_-_46747629 0.56 ENSMUST00000058636.9
helt bHLH transcription factor
chr9_+_20209828 0.54 ENSMUST00000215540.2
ENSMUST00000075717.7
olfactory receptor 873
chr11_+_118324652 0.52 ENSMUST00000106286.3
C1q and tumor necrosis factor related protein 1
chr7_-_139628991 0.51 ENSMUST00000172775.4
ENSMUST00000055353.9
msh homeobox 3
chr5_-_109372574 0.51 ENSMUST00000170341.3
vomeronasal 2, receptor 14
chr13_-_30039613 0.51 ENSMUST00000091674.12
ENSMUST00000006353.14
CDK5 regulatory subunit associated protein 1-like 1
chr11_-_74243447 0.50 ENSMUST00000141134.2
ENSMUST00000214769.2
olfactory receptor 411
chr4_-_112291169 0.49 ENSMUST00000058605.3
selection and upkeep of intraepithelial T cells 9
chrX_+_41578568 0.49 ENSMUST00000197237.2
TEX13 family member C2
chr1_-_155910567 0.49 ENSMUST00000141878.8
torsin A interacting protein 1
chr6_+_132928065 0.48 ENSMUST00000070991.5
taste receptor, type 2, member 129
chr6_+_5390386 0.48 ENSMUST00000183358.2
ankyrin repeat and SOCS box-containing 4
chr1_+_178233640 0.47 ENSMUST00000027775.9
EF-hand calcium binding domain 2
chr2_+_120459593 0.47 ENSMUST00000180041.9
START domain containing 9
chr19_-_12219023 0.46 ENSMUST00000087818.2
olfactory receptor 262
chr7_-_5808444 0.46 ENSMUST00000075085.7
vomeronasal 1 receptor 63
chr12_-_115567853 0.45 ENSMUST00000103538.3
ENSMUST00000198646.2
immunoglobulin heavy variable V1-67
chr16_+_65317389 0.45 ENSMUST00000176330.8
ENSMUST00000004964.15
ENSMUST00000176038.8
POU domain, class 1, transcription factor 1
chr16_-_55659194 0.44 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr16_-_44379226 0.44 ENSMUST00000114634.3
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr7_-_66915756 0.44 ENSMUST00000207715.2
myocyte enhancer factor 2A
chr9_+_38164715 0.44 ENSMUST00000093865.3
olfactory receptor 143
chr11_-_58059293 0.42 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr4_-_75196485 0.42 ENSMUST00000030103.9
distal membrane arm assembly complex 1
chr1_+_92500847 0.41 ENSMUST00000074859.3
olfactory receptor 1413
chr15_+_31224555 0.40 ENSMUST00000186109.2
death-associated protein
chr8_+_34007333 0.40 ENSMUST00000124496.8
testis expressed gene 15
chr2_-_37007795 0.40 ENSMUST00000213817.2
ENSMUST00000215927.2
olfactory receptor 362
chr11_+_113575208 0.40 ENSMUST00000042227.15
ENSMUST00000123466.2
ENSMUST00000106621.4
DNA segment, Chr 11, Wayne State University 47, expressed
chr2_-_88157559 0.40 ENSMUST00000214207.2
olfactory receptor 1175
chr5_+_5623799 0.39 ENSMUST00000101627.5
predicted gene 8773
chr9_+_38164070 0.38 ENSMUST00000213129.2
olfactory receptor 143
chr8_+_34006758 0.38 ENSMUST00000149399.8
testis expressed gene 15
chr5_-_86893645 0.38 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr9_+_64142483 0.38 ENSMUST00000039011.4
ubiquitin carboxyl-terminal esterase L4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.0 3.0 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.0 4.8 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8 2.3 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.7 2.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.6 1.9 GO:0045362 nitric oxide production involved in inflammatory response(GO:0002537) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.6 1.8 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495)
0.6 2.3 GO:2000521 negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256) negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.6 2.2 GO:0002879 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 1.7 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.4 1.8 GO:0006566 threonine metabolic process(GO:0006566)
0.3 1.0 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3 1.3 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 5.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3 0.9 GO:0000389 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.3 1.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.3 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.7 GO:0090383 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383)
0.2 2.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 3.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.6 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.6 GO:0009955 adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011)
0.2 1.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 1.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 21.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 5.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 27.9 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0051775 response to redox state(GO:0051775)
0.1 0.9 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 2.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.7 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 1.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 2.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 2.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 0.3 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:1990166 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.3 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 2.6 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.5 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 7.2 GO:0055001 muscle cell development(GO:0055001)
0.0 2.4 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 2.9 GO:0001824 blastocyst development(GO:0001824)
0.0 1.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 1.8 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0014010 Schwann cell proliferation(GO:0014010)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 15.0 GO:0042613 MHC class II protein complex(GO:0042613)
1.0 3.0 GO:0033193 Lsd1/2 complex(GO:0033193)
0.8 5.9 GO:0032437 cuticular plate(GO:0032437)
0.8 7.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 2.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.6 1.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 2.1 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.1 GO:0008623 CHRAC(GO:0008623)
0.3 1.3 GO:0034657 GID complex(GO:0034657)
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 2.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 1.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 1.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 13.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 2.6 GO:0005657 replication fork(GO:0005657)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 8.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 2.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.7 5.9 GO:0004875 complement receptor activity(GO:0004875)
0.6 1.8 GO:0042497 triacyl lipopeptide binding(GO:0042497)
0.6 2.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.6 1.7 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.5 2.1 GO:0050436 microfibril binding(GO:0050436)
0.5 2.4 GO:0051373 FATZ binding(GO:0051373)
0.3 1.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 5.4 GO:0005522 profilin binding(GO:0005522)
0.3 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.5 GO:0031013 troponin I binding(GO:0031013)
0.2 0.9 GO:1990460 leptin receptor binding(GO:1990460)
0.2 4.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 1.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 2.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 28.8 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0030622 U4atac snRNA binding(GO:0030622)
0.1 2.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 3.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 3.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.3 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 7.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0051287 NAD binding(GO:0051287)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 6.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.0 ST ADRENERGIC Adrenergic Pathway
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 2.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 5.7 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 5.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation