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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Mga

Z-value: 1.32

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Transcription factors associated with Mga

Gene Symbol Gene ID Gene Info
Mga
ENSMUSG00000033943.16 Mga

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mgamm39_v1_chr2_+_119727689_1197277860.262.9e-02Click!

Activity profile of Mga motif

Sorted Z-values of Mga motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mga

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_68414401 17.83 ENSMUST00000103324.3
Igkv15-103
immunoglobulin kappa chain variable 15-103
chr6_+_67838100 16.63 ENSMUST00000200586.2
ENSMUST00000103309.3
Igkv17-127
immunoglobulin kappa variable 17-127
chr11_-_120930193 15.27 ENSMUST00000026159.6
Cd7
CD7 antigen
chr6_-_69835868 15.15 ENSMUST00000103369.2
Igkv12-41
immunoglobulin kappa chain variable 12-41
chr12_-_114252202 13.25 ENSMUST00000195124.6
ENSMUST00000103481.3
Ighv3-6
immunoglobulin heavy variable 3-6
chr7_-_30579686 11.82 ENSMUST00000188157.7
ENSMUST00000190753.2
ENSMUST00000186154.7
ENSMUST00000190617.7
Cd22
CD22 antigen
chrX_+_35152460 11.45 ENSMUST00000033419.13
Dock11
dedicator of cytokinesis 11
chr6_+_67873135 10.73 ENSMUST00000103310.3
Igkv14-126
immunoglobulin kappa variable 14-126
chr14_-_56339915 9.80 ENSMUST00000015583.2
Ctsg
cathepsin G
chr6_+_70700207 9.75 ENSMUST00000103407.3
ENSMUST00000199487.2
Igkj3
immunoglobulin kappa joining 3
chr17_+_34524884 8.19 ENSMUST00000074557.11
H2-Eb1
histocompatibility 2, class II antigen E beta
chr17_+_34524841 8.16 ENSMUST00000235530.2
H2-Eb1
histocompatibility 2, class II antigen E beta
chr2_-_129213050 7.72 ENSMUST00000028881.14
Il1b
interleukin 1 beta
chr5_-_120915693 7.71 ENSMUST00000044833.9
Oas3
2'-5' oligoadenylate synthetase 3
chr15_-_66673425 7.39 ENSMUST00000168589.8
Sla
src-like adaptor
chr12_+_36042899 7.20 ENSMUST00000020898.12
Agr2
anterior gradient 2
chr1_+_52047368 7.05 ENSMUST00000027277.7
Stat4
signal transducer and activator of transcription 4
chr14_+_66043281 6.68 ENSMUST00000022612.10
Pbk
PDZ binding kinase
chr17_+_36172210 6.64 ENSMUST00000074259.15
ENSMUST00000174873.2
Nrm
nurim (nuclear envelope membrane protein)
chr6_+_70699822 6.07 ENSMUST00000198234.2
ENSMUST00000103406.2
Igkj2
immunoglobulin kappa joining 2
chr3_+_87283687 5.84 ENSMUST00000163661.8
ENSMUST00000072480.9
Fcrl1
Fc receptor-like 1
chr1_-_130350746 5.49 ENSMUST00000112488.9
ENSMUST00000119432.2
Cd55b
CD55 molecule, decay accelerating factor for complement B
chr5_+_149202157 5.17 ENSMUST00000200806.4
Alox5ap
arachidonate 5-lipoxygenase activating protein
chr3_+_87283767 4.99 ENSMUST00000194786.6
ENSMUST00000191666.2
Fcrl1
Fc receptor-like 1
chr4_+_132291369 4.90 ENSMUST00000070690.8
Ptafr
platelet-activating factor receptor
chr1_-_130390418 4.71 ENSMUST00000027650.13
Cd55
CD55 molecule, decay accelerating factor for complement
chr3_+_87283748 4.65 ENSMUST00000167200.7
Fcrl1
Fc receptor-like 1
chr7_-_3828640 4.35 ENSMUST00000189095.7
ENSMUST00000094911.5
ENSMUST00000153846.8
ENSMUST00000108619.8
ENSMUST00000108620.8
Gm15448
predicted gene 15448
chr11_+_116422712 4.32 ENSMUST00000100201.10
Sphk1
sphingosine kinase 1
chr6_+_123206802 4.23 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
Clec4n
C-type lectin domain family 4, member n
chr6_+_70699533 4.16 ENSMUST00000103405.2
Igkj1
immunoglobulin kappa joining 1
chr2_+_151414524 3.96 ENSMUST00000028950.9
Sdcbp2
syndecan binding protein (syntenin) 2
chr12_+_111387023 3.58 ENSMUST00000220852.2
Exoc3l4
exocyst complex component 3-like 4
chr4_-_116982804 3.44 ENSMUST00000183310.2
Btbd19
BTB (POZ) domain containing 19
chr6_+_129374441 3.41 ENSMUST00000112081.9
ENSMUST00000112079.3
Clec1b
C-type lectin domain family 1, member b
chr6_+_129374260 3.38 ENSMUST00000032262.14
Clec1b
C-type lectin domain family 1, member b
chr19_+_38043506 3.38 ENSMUST00000237408.2
Cep55
centrosomal protein 55
chr8_-_34578880 3.18 ENSMUST00000080152.5
Gm10131
predicted pseudogene 10131
chr8_-_84831391 3.15 ENSMUST00000041367.9
ENSMUST00000210279.2
Dcaf15
DDB1 and CUL4 associated factor 15
chr16_-_44153288 3.08 ENSMUST00000136381.8
Sidt1
SID1 transmembrane family, member 1
chr18_+_89215438 3.04 ENSMUST00000237110.2
Cd226
CD226 antigen
chr16_-_44153498 2.92 ENSMUST00000047446.13
Sidt1
SID1 transmembrane family, member 1
chr19_-_40576817 2.75 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr3_+_105778174 2.73 ENSMUST00000164730.2
ENSMUST00000010279.10
Adora3
Tmigd3
adenosine A3 receptor
transmembrane and immunoglobulin domain containing 3
chr5_+_137744228 2.58 ENSMUST00000100539.10
Tsc22d4
TSC22 domain family, member 4
chr6_-_41613322 2.52 ENSMUST00000031902.7
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr9_-_96993169 2.24 ENSMUST00000085206.11
Slc25a36
solute carrier family 25, member 36
chr9_+_59198829 2.24 ENSMUST00000217570.2
ENSMUST00000026266.9
Adpgk
ADP-dependent glucokinase
chr15_+_51740825 2.23 ENSMUST00000137116.3
ENSMUST00000161651.2
ENSMUST00000059599.10
Utp23
UTP23 small subunit processome component
chr2_+_84966569 2.22 ENSMUST00000057019.9
Aplnr
apelin receptor
chr8_+_83891972 2.22 ENSMUST00000034145.11
Tbc1d9
TBC1 domain family, member 9
chr8_+_3443018 2.18 ENSMUST00000004684.13
ENSMUST00000145394.3
Arhgef18
rho/rac guanine nucleotide exchange factor (GEF) 18
chr19_+_53298906 2.09 ENSMUST00000003870.15
Mxi1
MAX interactor 1, dimerization protein
chr1_+_75412574 2.00 ENSMUST00000037796.14
ENSMUST00000113584.8
ENSMUST00000145166.8
ENSMUST00000143730.8
ENSMUST00000133418.8
ENSMUST00000144874.8
ENSMUST00000140287.8
Gmppa
GDP-mannose pyrophosphorylase A
chr11_+_116421923 1.65 ENSMUST00000138840.8
Sphk1
sphingosine kinase 1
chr15_+_51741138 1.63 ENSMUST00000136129.2
Utp23
UTP23 small subunit processome component
chr7_+_48438751 1.61 ENSMUST00000118927.8
ENSMUST00000125280.8
Zdhhc13
zinc finger, DHHC domain containing 13
chr6_+_5390386 1.59 ENSMUST00000183358.2
Asb4
ankyrin repeat and SOCS box-containing 4
chrX_+_20483742 1.54 ENSMUST00000115375.8
ENSMUST00000115374.8
ENSMUST00000084383.10
Rbm10
RNA binding motif protein 10
chr10_+_75047897 1.45 ENSMUST00000218766.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr9_-_109025043 1.34 ENSMUST00000061456.8
Fbxw13
F-box and WD-40 domain protein 13
chr3_-_146227144 1.26 ENSMUST00000199079.2
ENSMUST00000029838.11
Rpf1
ribosome production factor 1 homolog
chr14_-_56137697 1.24 ENSMUST00000111325.5
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr14_+_32555912 1.17 ENSMUST00000104926.3
Fam170b
family with sequence similarity 170, member B
chr4_-_41314877 1.14 ENSMUST00000030145.9
Dcaf12
DDB1 and CUL4 associated factor 12
chr19_-_5660057 1.13 ENSMUST00000236229.2
ENSMUST00000235701.2
ENSMUST00000236264.2
Kat5
K(lysine) acetyltransferase 5
chr9_-_109531768 1.06 ENSMUST00000098359.4
Fbxw18
F-box and WD-40 domain protein 18
chr14_+_33775115 1.02 ENSMUST00000227979.2
Antxrl
anthrax toxin receptor-like
chr8_+_96260694 0.99 ENSMUST00000041569.5
Ccdc113
coiled-coil domain containing 113
chr8_-_106706035 0.99 ENSMUST00000034371.9
Dpep3
dipeptidase 3
chr9_-_109278192 0.99 ENSMUST00000084984.8
Fbxw16
F-box and WD-40 domain protein 16
chr6_-_56900709 0.99 ENSMUST00000205087.2
Nt5c3
5'-nucleotidase, cytosolic III
chr19_-_3955230 0.96 ENSMUST00000145791.8
Tcirg1
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr1_+_190661019 0.96 ENSMUST00000135364.7
Angel2
angel homolog 2
chr11_+_49094119 0.94 ENSMUST00000109198.8
ENSMUST00000137061.9
Zfp62
zinc finger protein 62
chr11_+_49094292 0.89 ENSMUST00000150284.8
ENSMUST00000109197.8
ENSMUST00000151228.2
Zfp62
zinc finger protein 62
chr1_-_74627123 0.87 ENSMUST00000027315.14
ENSMUST00000113737.8
Zfp142
zinc finger protein 142
chr7_+_27186335 0.86 ENSMUST00000008528.8
Sertad1
SERTA domain containing 1
chr3_-_94343874 0.85 ENSMUST00000204913.3
ENSMUST00000191506.8
ENSMUST00000199678.4
Oaz3
ornithine decarboxylase antizyme 3
chr1_-_74627264 0.71 ENSMUST00000066986.13
Zfp142
zinc finger protein 142
chr17_+_21031817 0.68 ENSMUST00000232810.2
ENSMUST00000233712.2
ENSMUST00000232852.2
Vmn1r229
vomeronasal 1 receptor 229
chr14_-_59678218 0.66 ENSMUST00000111253.3
ENSMUST00000095775.10
ENSMUST00000161459.8
Setdb2
SET domain, bifurcated 2
chr8_+_123338357 0.65 ENSMUST00000015157.10
Trappc2l
trafficking protein particle complex 2-like
chrY_-_70312506 0.63 ENSMUST00000185989.2
Gm29423
predicted gene 29423
chr9_-_108991088 0.58 ENSMUST00000199540.2
ENSMUST00000198076.5
ENSMUST00000054925.13
Fbxw21
F-box and WD-40 domain protein 21
chr2_+_83474779 0.51 ENSMUST00000081591.7
Zc3h15
zinc finger CCCH-type containing 15
chr17_-_32569480 0.50 ENSMUST00000235265.2
ENSMUST00000236503.2
ENSMUST00000050214.9
Akap8l
A kinase (PRKA) anchor protein 8-like
chr2_-_111400026 0.50 ENSMUST00000217772.2
ENSMUST00000207283.3
Olfr1295
olfactory receptor 1295
chr13_-_8921027 0.48 ENSMUST00000177404.2
ENSMUST00000176922.8
ENSMUST00000021572.11
Wdr37
WD repeat domain 37
chr9_-_109575157 0.46 ENSMUST00000071917.4
Fbxw26
F-box and WD-40 domain protein 26
chr7_-_4606104 0.42 ENSMUST00000049113.14
Ptprh
protein tyrosine phosphatase, receptor type, H
chr4_-_62443273 0.38 ENSMUST00000030091.10
Pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr5_+_108777855 0.38 ENSMUST00000078323.13
ENSMUST00000120327.3
Tmem175
transmembrane protein 175
chr9_-_85631361 0.36 ENSMUST00000039213.15
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_-_124490296 0.33 ENSMUST00000111472.6
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr7_-_126497421 0.32 ENSMUST00000121532.8
ENSMUST00000032926.12
Tmem219
transmembrane protein 219
chr9_-_96360676 0.25 ENSMUST00000057500.6
Rnf7
ring finger protein 7
chr9_-_96360648 0.19 ENSMUST00000071301.5
Rnf7
ring finger protein 7
chr8_+_46387647 0.16 ENSMUST00000095326.10
Ccdc110
coiled-coil domain containing 110
chr14_+_53032576 0.11 ENSMUST00000180687.3
Trav6d-5
T cell receptor alpha variable 6D-5
chr14_-_60414932 0.00 ENSMUST00000140924.3
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_-_109455125 0.00 ENSMUST00000073962.8
Fbxw24
F-box and WD-40 domain protein 24

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.4 7.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.2 4.9 GO:1902941 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
1.2 4.7 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
1.0 9.8 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
1.0 7.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.9 2.7 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.9 5.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.9 6.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.8 16.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.8 3.9 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.7 11.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.6 2.2 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.5 6.0 GO:0033227 dsRNA transport(GO:0033227)
0.5 3.0 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.4 2.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3 2.7 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 15.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 1.2 GO:0080154 regulation of fertilization(GO:0080154)
0.2 2.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 3.6 GO:0051601 exocyst localization(GO:0051601)
0.2 2.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 6.8 GO:0030220 platelet formation(GO:0030220)
0.1 3.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 1.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 18.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 4.2 GO:0050832 defense response to fungus(GO:0050832)
0.1 6.7 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 16.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 7.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 1.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 2.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 2.2 GO:0006096 glycolytic process(GO:0006096)
0.0 7.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.0 GO:0007140 male meiosis(GO:0007140)
0.0 4.2 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.7 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.0 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 16.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 6.6 GO:0005652 nuclear lamina(GO:0005652)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 3.4 GO:0090543 Flemming body(GO:0090543)
0.2 1.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 3.6 GO:0000145 exocyst(GO:0000145)
0.1 9.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 13.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.9 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 19.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0005921 gap junction(GO:0005921)
0.0 1.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 7.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 7.7 GO:0030141 secretory granule(GO:0030141)
0.0 5.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.0 6.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9 2.7 GO:0004350 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.8 4.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.7 6.0 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.6 7.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 11.8 GO:0015026 coreceptor activity(GO:0015026)
0.3 3.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 7.2 GO:0002162 dystroglycan binding(GO:0002162)
0.3 7.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 7.5 GO:0001618 virus receptor activity(GO:0001618)
0.2 2.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 28.4 GO:0003823 antigen binding(GO:0003823)
0.1 7.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 13.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.2 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 9.8 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 7.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.6 GO:0000149 SNARE binding(GO:0000149)
0.0 3.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 4.0 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 7.0 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 9.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 11.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 15.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 11.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 4.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 7.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 2.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 4.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 12.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 7.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 6.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors