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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Msx2_Hoxd4

Z-value: 0.65

Motif logo

Transcription factors associated with Msx2_Hoxd4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021469.10 Msx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Msx2mm39_v1_chr13_-_53627110_536271100.123.1e-01Click!

Activity profile of Msx2_Hoxd4 motif

Sorted Z-values of Msx2_Hoxd4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx2_Hoxd4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_6673167 6.33 ENSMUST00000163073.2
FYN binding protein
chr11_+_67061908 4.94 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr11_+_67061837 4.77 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr1_-_144427302 2.90 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr3_-_14843512 2.84 ENSMUST00000094365.11
carbonic anhydrase 1
chr3_-_75177378 2.71 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr5_-_62923463 2.64 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_68233361 2.22 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chr4_-_96673423 2.17 ENSMUST00000107071.2
predicted gene 12695
chr2_+_4022537 2.15 ENSMUST00000177457.8
FERM domain containing 4A
chrX_+_158491589 2.06 ENSMUST00000080394.13
SH3-domain kinase binding protein 1
chr18_+_4920513 2.05 ENSMUST00000126977.8
supervillin
chr3_+_40755211 1.88 ENSMUST00000204473.2
polo like kinase 4
chr13_+_49761506 1.86 ENSMUST00000021822.7
osteoglycin
chr13_+_49697919 1.80 ENSMUST00000177948.2
ENSMUST00000021820.14
asporin
chr14_+_79753055 1.76 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr1_-_149836974 1.76 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_-_46033353 1.72 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr1_-_165535654 1.59 ENSMUST00000097474.9
RCSD domain containing 1
chr7_-_45570828 1.59 ENSMUST00000038876.13
epithelial membrane protein 3
chrX_+_55500170 1.55 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr1_+_45834645 1.54 ENSMUST00000147308.2
WD repeat domain 75
chr2_-_84255602 1.51 ENSMUST00000074262.9
calcitonin receptor-like
chr6_-_136918885 1.49 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_45570254 1.46 ENSMUST00000164119.3
epithelial membrane protein 3
chr6_-_69584812 1.38 ENSMUST00000103359.3
immunoglobulin kappa variable 4-55
chr7_-_45570538 1.37 ENSMUST00000210297.2
epithelial membrane protein 3
chr6_+_149226891 1.36 ENSMUST00000189837.2
retroelement silencing factor 1
chrX_+_158086253 1.35 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr18_-_43610829 1.35 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr10_-_107321938 1.33 ENSMUST00000000445.2
myogenic factor 5
chr6_-_124756645 1.33 ENSMUST00000147669.2
ENSMUST00000128697.8
ENSMUST00000032218.10
ENSMUST00000112475.9
leucine rich repeat containing 23
chr7_-_45570674 1.32 ENSMUST00000210939.2
epithelial membrane protein 3
chr3_-_49711706 1.29 ENSMUST00000191794.2
protocadherin 18
chr2_-_72817060 1.28 ENSMUST00000112062.2
predicted gene 11084
chr15_-_101422054 1.26 ENSMUST00000230067.3
predicted gene, 49425
chr2_-_45002902 1.21 ENSMUST00000076836.13
ENSMUST00000176732.8
ENSMUST00000200844.4
zinc finger E-box binding homeobox 2
chr3_-_49711765 1.20 ENSMUST00000035931.13
protocadherin 18
chr6_-_129449739 1.20 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr5_-_23821523 1.18 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr7_-_73191484 1.15 ENSMUST00000197642.2
ENSMUST00000026895.14
ENSMUST00000169922.9
chromodomain helicase DNA binding protein 2
chr13_+_19398273 1.11 ENSMUST00000103558.3
T cell receptor gamma, constant 1
chr5_+_17779273 1.06 ENSMUST00000030568.14
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_+_44237577 1.06 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr6_-_87510200 1.06 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr9_-_114219685 1.05 ENSMUST00000084881.5
cartilage associated protein
chr3_+_32490300 1.04 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr10_-_63039709 0.99 ENSMUST00000095580.3
myopalladin
chrX_+_132751729 0.95 ENSMUST00000033602.9
tenomodulin
chr6_-_129600798 0.94 ENSMUST00000095412.10
killer cell lectin-like receptor subfamily K, member 1
chr6_-_129600812 0.94 ENSMUST00000168919.8
killer cell lectin-like receptor subfamily K, member 1
chrX_+_135145813 0.93 ENSMUST00000048687.11
transcription elongation factor A like 9
chr7_-_120673761 0.93 ENSMUST00000047194.4
immunoglobulin superfamily, member 6
chr2_-_163259012 0.91 ENSMUST00000127038.2
oxidative stress responsive serine rich 1
chr4_-_3872105 0.91 ENSMUST00000105158.2
Moloney sarcoma oncogene
chr12_-_76224025 0.86 ENSMUST00000101291.11
ENSMUST00000218621.2
ENSMUST00000076634.5
estrogen receptor 2 (beta)
chr9_-_107482494 0.83 ENSMUST00000102529.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_-_115459082 0.83 ENSMUST00000206123.2
SRY (sex determining region Y)-box 6
chr3_-_68911835 0.82 ENSMUST00000107812.8
intraflagellar transport 80
chr13_+_51562675 0.81 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr2_+_74522258 0.80 ENSMUST00000061745.5
homeobox D10
chr8_+_82582953 0.79 ENSMUST00000109851.3
inositol polyphosphate-4-phosphatase, type II
chr3_-_146200870 0.78 ENSMUST00000093951.3
spermatogenesis associated 1
chr1_-_156766351 0.78 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr3_-_68911807 0.78 ENSMUST00000154741.8
ENSMUST00000148031.2
intraflagellar transport 80
chr2_-_73284262 0.77 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr16_+_14523696 0.77 ENSMUST00000023356.8
snail family zinc finger 2
chr19_+_45433899 0.75 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr4_-_82768958 0.74 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chr11_+_98689479 0.73 ENSMUST00000037930.13
male specific lethal 1
chr7_+_140181182 0.71 ENSMUST00000214180.2
ENSMUST00000211771.2
olfactory receptor 46
chrX_+_100683662 0.71 ENSMUST00000119299.8
ENSMUST00000044475.5
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr9_-_107482462 0.68 ENSMUST00000194433.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_-_45000389 0.68 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
zinc finger E-box binding homeobox 2
chr18_+_34973605 0.67 ENSMUST00000043484.8
receptor accessory protein 2
chr2_-_59955995 0.67 ENSMUST00000112550.8
bromodomain adjacent to zinc finger domain, 2B
chr8_+_31601837 0.66 ENSMUST00000046941.8
ENSMUST00000217278.2
ring finger protein 122
chr7_-_113716996 0.66 ENSMUST00000069449.7
related RAS viral (r-ras) oncogene 2
chr12_-_113896002 0.65 ENSMUST00000103463.3
immunoglobulin heavy variable 14-1
chr9_-_107648144 0.65 ENSMUST00000183248.3
ENSMUST00000182022.8
ENSMUST00000035199.13
ENSMUST00000182659.8
RNA binding motif protein 5
chr10_+_101994841 0.64 ENSMUST00000020039.13
MGAT4 family, member C
chr6_-_23650297 0.61 ENSMUST00000063548.4
ring finger protein 133
chr7_+_89814713 0.60 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr1_-_156766381 0.60 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr6_+_29361408 0.57 ENSMUST00000156163.2
calumenin
chr6_+_124281607 0.57 ENSMUST00000032234.5
ENSMUST00000112541.8
CD163 antigen
chrX_+_149330371 0.57 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr3_+_7494108 0.57 ENSMUST00000193330.2
protein kinase inhibitor, alpha
chr3_+_84859453 0.57 ENSMUST00000029727.8
F-box and WD-40 domain protein 7
chr17_+_46471950 0.56 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr11_-_79421397 0.56 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr13_-_103042554 0.55 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr18_+_44237474 0.54 ENSMUST00000081271.7
serine peptidase inhibitor, Kazal type 12
chr12_-_113733922 0.52 ENSMUST00000180013.3
immunoglobulin heavy variable 2-9-1
chr2_-_152422220 0.50 ENSMUST00000053180.4
defensin beta 19
chr10_+_5543769 0.50 ENSMUST00000051809.10
myc target 1
chr13_+_21546990 0.50 ENSMUST00000225545.2
ENSMUST00000053293.14
zinc finger and SCAN domain containing 12
chr1_-_80255156 0.49 ENSMUST00000168372.2
cullin 3
chr8_-_26609153 0.48 ENSMUST00000037182.14
hook microtubule tethering protein 3
chr3_-_144275897 0.48 ENSMUST00000043325.9
heparan sulfate 2-O-sulfotransferase 1
chr4_+_122730027 0.48 ENSMUST00000030412.11
ENSMUST00000121870.8
ENSMUST00000097902.5
palmitoyl-protein thioesterase 1
chr5_-_121641461 0.48 ENSMUST00000079368.5
a disintegrin and metallopeptidase domain 1b
chr13_-_21330037 0.48 ENSMUST00000216039.3
olfactory receptor 1368
chr18_+_9707595 0.47 ENSMUST00000234965.2
collectin sub-family member 12
chr3_-_75072319 0.47 ENSMUST00000124618.2
zinc finger, B-box domain containing
chr3_+_137770813 0.46 ENSMUST00000163080.3
RIKEN cDNA 1110002E22 gene
chr1_+_165616315 0.45 ENSMUST00000161559.3
CD247 antigen
chr2_+_20742115 0.45 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr13_-_103042294 0.44 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr10_-_89270554 0.44 ENSMUST00000220071.2
growth arrest-specific 2 like 3
chr6_-_13871475 0.43 ENSMUST00000139231.2
RIKEN cDNA 2610001J05 gene
chr2_+_89642395 0.43 ENSMUST00000214508.2
olfactory receptor 1255
chr14_-_36641270 0.43 ENSMUST00000182797.8
coiled-coil serine rich 2
chr1_+_53100796 0.42 ENSMUST00000027269.7
ENSMUST00000191197.2
myostatin
chr4_+_109092610 0.42 ENSMUST00000106628.8
calreticulin 4
chr1_-_155293141 0.41 ENSMUST00000111775.8
ENSMUST00000111774.2
xenotropic and polytropic retrovirus receptor 1
chr9_-_56151334 0.41 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr17_-_37523969 0.41 ENSMUST00000060728.7
ENSMUST00000216318.2
olfactory receptor 95
chr16_+_27126239 0.41 ENSMUST00000066852.9
osteocrin
chr19_+_26727111 0.41 ENSMUST00000175842.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_59197746 0.40 ENSMUST00000000128.10
ENSMUST00000108783.4
wingless-type MMTV integration site family, member 9A
chr11_-_73742280 0.40 ENSMUST00000213365.2
olfactory receptor 393
chr10_+_128139191 0.40 ENSMUST00000005825.8
PAN2 poly(A) specific ribonuclease subunit
chr18_+_7905440 0.40 ENSMUST00000170854.2
WW domain containing adaptor with coiled-coil
chr19_-_24178000 0.39 ENSMUST00000233658.3
tight junction protein 2
chr14_-_30973164 0.37 ENSMUST00000226565.2
ENSMUST00000022459.5
PHD finger protein 7
chr7_-_84328553 0.37 ENSMUST00000069537.3
ENSMUST00000207865.2
ENSMUST00000178385.9
ENSMUST00000208782.2
zinc finger, AN1-type domain 6
chr13_+_76115824 0.37 ENSMUST00000022081.3
spermatogenesis associated 9
chr14_+_54183465 0.37 ENSMUST00000197130.5
ENSMUST00000103677.3
T cell receptor delta variable 2-1
chr6_-_23650205 0.37 ENSMUST00000115354.2
ring finger protein 133
chr6_-_57877975 0.36 ENSMUST00000228322.2
vomeronasal 1 receptor 22
chr2_+_83554770 0.36 ENSMUST00000141725.3
integrin alpha V
chr14_+_53562089 0.35 ENSMUST00000178100.3
T cell receptor alpha variable 7N-6
chr1_-_132318039 0.34 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr14_-_86986541 0.34 ENSMUST00000226254.2
diaphanous related formin 3
chr18_-_38102799 0.34 ENSMUST00000166148.8
ENSMUST00000163131.8
ENSMUST00000043437.14
FCH and double SH3 domains 1
chr17_-_29226700 0.34 ENSMUST00000233441.2
serine/threonine kinase 38
chr1_+_171668122 0.34 ENSMUST00000135386.2
CD84 antigen
chr4_-_43710231 0.34 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr2_+_85809620 0.34 ENSMUST00000056849.3
olfactory receptor 1030
chr13_-_43634695 0.34 ENSMUST00000144326.4
RAN binding protein 9
chr14_-_50586329 0.33 ENSMUST00000216634.2
olfactory receptor 735
chr5_-_53864874 0.33 ENSMUST00000031093.5
cholecystokinin A receptor
chr5_-_151351628 0.33 ENSMUST00000202365.2
ENSMUST00000186838.2
predicted gene 42906
RIKEN cDNA D730045B01 gene
chr9_+_30853837 0.33 ENSMUST00000068135.13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr9_+_37400317 0.33 ENSMUST00000239459.2
Myb/SANT-like DNA-binding domain containing 2
chr2_-_104324035 0.33 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr15_+_41694317 0.32 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr1_+_33947250 0.32 ENSMUST00000183034.5
dystonin
chr15_-_3333003 0.31 ENSMUST00000165386.2
coiled-coil domain containing 152
chr2_+_57887896 0.31 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr11_-_87716849 0.29 ENSMUST00000103177.10
lactoperoxidase
chr10_-_14421368 0.29 ENSMUST00000208429.3
adhesion G protein-coupled receptor G6
chr10_+_127256736 0.29 ENSMUST00000064793.13
R3H domain containing 2
chr6_+_83142902 0.29 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr14_+_53599724 0.28 ENSMUST00000196105.2
T cell receptor alpha variable 13N-4
chr13_+_118851214 0.28 ENSMUST00000022246.9
fibroblast growth factor 10
chr18_+_37453427 0.28 ENSMUST00000078271.4
protocadherin beta 5
chr10_+_127257077 0.27 ENSMUST00000168780.8
R3H domain containing 2
chr18_-_3309858 0.26 ENSMUST00000144496.8
ENSMUST00000154715.8
cAMP responsive element modulator
chr6_-_40906665 0.26 ENSMUST00000136499.2
RIKEN cDNA 1700074P13 gene
chr11_-_99482165 0.25 ENSMUST00000104930.2
keratin associated protein 1-3
chr11_-_66059330 0.25 ENSMUST00000080665.10
dynein, axonemal, heavy chain 9
chr5_-_123127346 0.24 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr11_-_99265721 0.24 ENSMUST00000006963.3
keratin 28
chr15_-_36165017 0.24 ENSMUST00000058643.4
F-box protein 43
chr14_-_56137697 0.24 ENSMUST00000111325.5
short chain dehydrogenase/reductase family 39U, member 1
chr1_-_14380418 0.23 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1
chrX_+_21350783 0.23 ENSMUST00000089188.9
angiotensin II receptor, type 2
chr10_+_127256993 0.23 ENSMUST00000170336.8
R3H domain containing 2
chr2_-_32976378 0.23 ENSMUST00000049618.9
GTPase activating RANGAP domain-like 3
chr19_-_55229668 0.22 ENSMUST00000069183.8
guanylate cyclase 2g
chr7_+_122723365 0.21 ENSMUST00000205514.2
ENSMUST00000094053.7
trinucleotide repeat containing 6a
chr6_-_39702381 0.21 ENSMUST00000002487.15
Braf transforming gene
chr10_-_129107354 0.20 ENSMUST00000204573.3
olfactory receptor 777
chr5_-_72325482 0.20 ENSMUST00000196241.2
ENSMUST00000013693.11
COMM domain containing 8
chr15_+_38869415 0.20 ENSMUST00000179165.9
frizzled class receptor 6
chr6_+_15196950 0.19 ENSMUST00000140557.8
ENSMUST00000131414.8
ENSMUST00000115469.8
forkhead box P2
chr3_+_144283355 0.19 ENSMUST00000151086.3
selenoprotein F
chr6_+_29853745 0.19 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chrX_+_105626790 0.19 ENSMUST00000101296.9
ENSMUST00000101297.4
predicted gene 5127
chr12_+_108145802 0.19 ENSMUST00000221167.2
cyclin K
chr9_-_96513529 0.19 ENSMUST00000034984.8
RAS p21 protein activator 2
chr6_+_24733239 0.19 ENSMUST00000031690.6
hyaluronoglucosaminidase 6
chr15_+_58004793 0.18 ENSMUST00000227142.2
ENSMUST00000226955.2
WDYHV motif containing 1
chr6_+_83985684 0.18 ENSMUST00000203803.3
ENSMUST00000204591.3
ENSMUST00000113823.8
ENSMUST00000153860.4
dysferlin
chr1_+_179788037 0.18 ENSMUST00000097453.9
ENSMUST00000111117.8
CDC42 binding protein kinase alpha
chr5_+_107655487 0.17 ENSMUST00000143074.2
predicted gene 42669
chr1_+_60948149 0.17 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr14_+_8283087 0.17 ENSMUST00000206298.3
ENSMUST00000216079.2
olfactory receptor 720
chr11_-_99494134 0.17 ENSMUST00000072306.4
predicted gene 11938
chr1_+_179788675 0.17 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr19_-_47680528 0.17 ENSMUST00000026045.14
ENSMUST00000086923.6
collagen, type XVII, alpha 1
chr5_-_82271183 0.15 ENSMUST00000186079.2
ENSMUST00000185607.2
RIKEN cDNA 1700031L13 gene
chr7_-_101494472 0.15 ENSMUST00000211566.2
ENSMUST00000094141.7
ENSMUST00000209329.2
folate receptor 2 (fetal)
chr9_+_38788422 0.14 ENSMUST00000078289.3
olfactory receptor 926
chr15_-_36164963 0.14 ENSMUST00000227793.2
F-box protein 43
chr11_-_99457456 0.14 ENSMUST00000055502.5
keratin associated protein 3-1
chr1_+_128079543 0.13 ENSMUST00000189317.3
R3H domain containing 1
chrX_+_106836189 0.13 ENSMUST00000101292.9
terminal nucleotidyltransferase 5D

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.6 1.7 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.5 9.9 GO:0001778 plasma membrane repair(GO:0001778)
0.4 1.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.4 1.8 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 1.0 GO:1901874 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.3 1.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3 0.9 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 0.9 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.3 1.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.8 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.7 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 1.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 0.6 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.2 1.2 GO:0035063 nuclear speck organization(GO:0035063)
0.2 5.7 GO:0032060 bleb assembly(GO:0032060)
0.2 1.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 1.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 1.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.6 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 1.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 1.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.3 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.7 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.3 GO:0061033 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.4 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.5 GO:0071630 trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.1 GO:0061738 late endosomal microautophagy(GO:0061738)
0.1 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:0021993 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.2 GO:0035566 regulation of metanephros size(GO:0035566)
0.1 6.3 GO:0045576 mast cell activation(GO:0045576)
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.4 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 3.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 1.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 2.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 1.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 1.9 GO:0098536 deuterosome(GO:0098536)
0.2 0.6 GO:0034683 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 2.5 GO:0042588 zymogen granule(GO:0042588)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.0 1.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.5 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.5 1.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 0.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 2.8 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.8 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 1.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.6 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0070773 protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 2.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 2.3 GO:0003823 antigen binding(GO:0003823)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 6.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 5.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis