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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Msx3

Z-value: 0.78

Motif logo

Transcription factors associated with Msx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025469.11 Msx3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Msx3mm39_v1_chr7_-_139628991_1396290070.191.2e-01Click!

Activity profile of Msx3 motif

Sorted Z-values of Msx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_32977182 6.05 ENSMUST00000102810.10
GTPase activating RANGAP domain-like 3
chr2_-_32976378 5.94 ENSMUST00000049618.9
GTPase activating RANGAP domain-like 3
chr2_+_96148418 5.40 ENSMUST00000135431.8
ENSMUST00000162807.9
leucine rich repeat containing 4C
chr11_+_69909245 4.89 ENSMUST00000231415.2
ENSMUST00000108588.9
discs large MAGUK scaffold protein 4
chr1_-_52230062 4.74 ENSMUST00000156887.8
ENSMUST00000129107.2
glutaminase
chr15_+_82136598 4.70 ENSMUST00000136948.3
RIKEN cDNA 1500009C09 gene
chr10_+_81093110 4.56 ENSMUST00000117488.8
ENSMUST00000105328.10
ENSMUST00000121205.8
megakaryocyte-associated tyrosine kinase
chr14_+_60615128 4.36 ENSMUST00000022561.9
APC membrane recruitment 2
chr18_+_37952556 4.12 ENSMUST00000055935.11
protocadherin gamma subfamily C, 5
chr3_+_66893280 3.89 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chr3_+_66892979 3.59 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chr8_-_25215778 3.58 ENSMUST00000171438.8
ENSMUST00000171611.9
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr12_+_102094977 3.53 ENSMUST00000159329.8
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_-_75946790 3.35 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr19_+_13208692 3.23 ENSMUST00000207246.4
olfactory receptor 1463
chr16_+_49519561 3.21 ENSMUST00000046777.11
ENSMUST00000142682.9
intraflagellar transport 57
chrX_-_74621828 3.14 ENSMUST00000033545.6
RAB39B, member RAS oncogene family
chr5_+_14564932 3.12 ENSMUST00000182407.8
ENSMUST00000030691.17
piccolo (presynaptic cytomatrix protein)
chr3_+_66893031 3.10 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr7_+_45271229 2.97 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr11_-_99134885 2.90 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr4_+_102112189 2.89 ENSMUST00000106908.9
phosphodiesterase 4B, cAMP specific
chr12_+_72488625 2.88 ENSMUST00000161284.3
ENSMUST00000162159.8
leucine rich repeat containing 9
chr6_+_8948608 2.76 ENSMUST00000160300.2
neurexophilin 1
chr2_+_83642910 2.70 ENSMUST00000051454.4
family with sequence similarity 171, member B
chr18_+_37952596 2.54 ENSMUST00000193890.2
ENSMUST00000193941.2
protocadherin gamma subfamily C, 5
chr2_+_87696836 2.52 ENSMUST00000213308.3
olfactory receptor 1152
chr18_+_37827413 2.46 ENSMUST00000193414.2
protocadherin gamma subfamily A, 5
chr1_-_171854818 2.37 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr2_+_124978518 2.34 ENSMUST00000238754.2
cortexin 2
chr7_+_101545547 2.31 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr5_+_88731386 2.24 ENSMUST00000031229.11
RUN and FYVE domain containing 3
chr1_+_104696235 2.16 ENSMUST00000062528.9
cadherin 20
chr8_+_107757847 2.06 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr15_+_38662158 2.02 ENSMUST00000022904.8
ENSMUST00000228820.2
ATPase, H+ transporting, lysosomal V1 subunit C1
chr16_-_29363671 2.02 ENSMUST00000039090.9
ATPase type 13A4
chr5_+_88731366 1.99 ENSMUST00000199312.5
RUN and FYVE domain containing 3
chr2_+_124978612 1.94 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr17_+_34457868 1.88 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
histocompatibility 2, O region beta locus
chrX_-_111315519 1.86 ENSMUST00000124335.8
spermidine/spermine N1-acetyl transferase-like 1
chr6_-_135231324 1.86 ENSMUST00000111911.9
ENSMUST00000111910.4
germ cell associated 1
chr7_+_140181182 1.85 ENSMUST00000214180.2
ENSMUST00000211771.2
olfactory receptor 46
chr7_+_143838191 1.80 ENSMUST00000097929.4
SH3 and multiple ankyrin repeat domains 2
chr10_+_29074950 1.78 ENSMUST00000217011.2
predicted gene, 49353
chrX_-_142716200 1.74 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr3_+_18002574 1.74 ENSMUST00000029080.5
cysteine-rich perinuclear theca 12
chr1_-_97055931 1.69 ENSMUST00000027569.14
solute carrier organic anion transporter family, member 6c1
chr13_-_78344492 1.69 ENSMUST00000125176.3
nuclear receptor subfamily 2, group F, member 1
chr3_-_41696906 1.66 ENSMUST00000026866.15
sodium channel and clathrin linker 1
chr19_-_11261177 1.61 ENSMUST00000186937.7
ENSMUST00000067673.13
membrane-spanning 4-domains, subfamily A, member 5
chr1_-_158183894 1.60 ENSMUST00000004133.11
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr5_+_104350475 1.52 ENSMUST00000066708.7
dentin matrix protein 1
chr9_-_53882530 1.51 ENSMUST00000048409.14
ELMO/CED-12 domain containing 1
chr6_+_134617903 1.42 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chrX_+_106299484 1.39 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr12_-_114443071 1.37 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr13_+_68011442 1.36 ENSMUST00000078471.7
cDNA sequence BC048507
chr4_+_134658209 1.33 ENSMUST00000030622.3
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr6_-_135231168 1.32 ENSMUST00000111909.8
germ cell associated 1
chr10_-_84963841 1.28 ENSMUST00000214193.2
ENSMUST00000050813.4
ENSMUST00000217027.2
mitochondrial transcription termination factor 2
chr4_+_102111936 1.28 ENSMUST00000106907.9
phosphodiesterase 4B, cAMP specific
chr2_-_45007407 1.24 ENSMUST00000176438.9
zinc finger E-box binding homeobox 2
chr8_+_66964401 1.21 ENSMUST00000002025.5
ENSMUST00000183187.2
transketolase-like 2
chr7_+_101546059 1.17 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chrX_+_152506577 1.14 ENSMUST00000140575.8
ENSMUST00000208373.2
ENSMUST00000185492.7
ENSMUST00000149514.8
negative regulator of P-body association
chr2_+_163500290 1.08 ENSMUST00000164399.8
ENSMUST00000064703.13
ENSMUST00000099105.9
ENSMUST00000152418.8
ENSMUST00000126182.8
ENSMUST00000131228.8
protein kinase inhibitor, gamma
chr14_+_122272069 1.07 ENSMUST00000045976.7
translocase of inner mitochondrial membrane 8A2
chr4_-_43710231 1.03 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr17_+_30940015 1.00 ENSMUST00000236948.2
dynein, axonemal, heavy chain 8
chrX_-_88976458 0.96 ENSMUST00000088146.3
RIKEN cDNA 4930415L06 gene
chr14_+_65612788 0.95 ENSMUST00000224687.2
zinc finger protein 395
chr2_+_121786892 0.87 ENSMUST00000110578.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_-_174188505 0.86 ENSMUST00000168292.2
predicted gene, 20721
chr2_+_121787131 0.84 ENSMUST00000110574.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrX_+_9751861 0.83 ENSMUST00000067529.9
ENSMUST00000086165.4
synaptotagmin-like 5
chr17_-_24746911 0.81 ENSMUST00000176652.8
TNF receptor-associated factor 7
chr8_+_57964921 0.81 ENSMUST00000067925.8
high mobility group box 2
chr11_+_109434519 0.81 ENSMUST00000106696.2
arylsulfatase G
chr3_-_129834788 0.80 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr10_+_88215079 0.80 ENSMUST00000130301.8
ENSMUST00000020251.10
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr9_-_40895756 0.80 ENSMUST00000180872.9
cytotoxic and regulatory T cell molecule
chr5_-_140986312 0.78 ENSMUST00000085786.7
caspase recruitment domain family, member 11
chr7_+_89814713 0.76 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr5_-_105198913 0.73 ENSMUST00000112718.5
guanylate-binding protein 8
chr3_+_94745009 0.68 ENSMUST00000107266.8
ENSMUST00000042402.12
ENSMUST00000107269.2
pogo transposable element with ZNF domain
chr16_+_11224481 0.66 ENSMUST00000122168.8
sorting nexin 29
chr2_+_87686206 0.65 ENSMUST00000217376.2
olfactory receptor 1151
chr17_+_49922129 0.65 ENSMUST00000162854.2
kinesin family member 6
chr17_+_21603985 0.61 ENSMUST00000056107.11
ENSMUST00000162659.2
zinc finger protein 677
chr11_+_6366259 0.57 ENSMUST00000213200.2
peptidylprolyl isomerase A
chr2_-_111843053 0.57 ENSMUST00000213559.3
olfactory receptor 1310
chr11_+_53324126 0.56 ENSMUST00000018382.7
growth differentiation factor 9
chr2_+_89642395 0.50 ENSMUST00000214508.2
olfactory receptor 1255
chr2_-_150097511 0.40 ENSMUST00000063463.6
predicted gene 21994
chrX_-_142716085 0.38 ENSMUST00000087313.10
doublecortin
chr13_+_22508759 0.36 ENSMUST00000226225.2
ENSMUST00000227017.2
vomeronasal 1 receptor 197
chr7_+_3648264 0.35 ENSMUST00000206287.2
ENSMUST00000038913.16
CCR4-NOT transcription complex, subunit 3
chr10_+_88214989 0.34 ENSMUST00000127615.8
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr1_-_144427302 0.30 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr3_+_94744844 0.30 ENSMUST00000107270.9
pogo transposable element with ZNF domain
chr11_-_73382303 0.30 ENSMUST00000119863.2
ENSMUST00000215358.2
ENSMUST00000214623.2
olfactory receptor 381
chr17_-_24746804 0.21 ENSMUST00000176353.8
ENSMUST00000176237.8
TNF receptor-associated factor 7
chr3_+_41697046 0.20 ENSMUST00000120167.8
ENSMUST00000108065.9
ENSMUST00000146165.8
ENSMUST00000192193.6
ENSMUST00000119572.8
ENSMUST00000026867.14
ENSMUST00000026868.13
DNA segment, Chr 3, ERATO Doi 751, expressed
chr2_-_87504008 0.20 ENSMUST00000213835.2
olfactory receptor 1135
chr13_+_19394484 0.19 ENSMUST00000200495.2
T cell receptor gamma joining 1
chr4_-_14621497 0.19 ENSMUST00000149633.2
solute carrier family 26, member 7
chr9_+_38516398 0.18 ENSMUST00000217057.2
olfactory receptor 914
chr11_+_94218810 0.18 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr8_+_57964956 0.16 ENSMUST00000210871.2
high mobility group box 2
chr10_-_88214913 0.15 ENSMUST00000138159.2
DNA-damage regulated autophagy modulator 1
chr8_+_46080746 0.12 ENSMUST00000145458.9
ENSMUST00000134321.8
sorbin and SH3 domain containing 2
chr13_+_22268610 0.09 ENSMUST00000228243.2
ENSMUST00000226680.2
vomeronasal 1 receptor 188
chr1_-_34478753 0.07 ENSMUST00000042493.10
coiled-coil domain containing 115
chr13_+_23191826 0.06 ENSMUST00000228758.2
ENSMUST00000228031.2
ENSMUST00000227573.2
vomeronasal 1 receptor 213
chr13_-_23420117 0.05 ENSMUST00000235574.2
ENSMUST00000226672.3
vomeronasal 1 receptor 222
chr1_+_177557380 0.03 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr19_+_12257218 0.02 ENSMUST00000207186.4
ENSMUST00000207915.2
olfactory receptor 1434
chr3_+_82962823 0.01 ENSMUST00000150268.8
ENSMUST00000122128.2
pleiotropic regulator 1
chr9_+_72714156 0.00 ENSMUST00000055535.9
protogenin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.8 2.4 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.8 4.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.7 2.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.6 1.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.4 1.3 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.4 1.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.4 1.9 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 4.9 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3 4.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 1.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.3 0.8 GO:0002355 detection of tumor cell(GO:0002355)
0.2 3.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 0.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 3.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 3.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 3.5 GO:0097186 amelogenesis(GO:0097186)
0.1 4.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.8 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.4 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 3.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 2.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.6 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 7.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 3.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 5.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.0 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.8 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 1.8 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 4.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 4.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 11.9 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 9.8 GO:0050808 synapse organization(GO:0050808)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.4 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0032418 lysosome localization(GO:0032418)
0.0 1.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0044317 rod spherule(GO:0044317)
0.8 2.4 GO:0060187 cell pole(GO:0060187)
0.5 2.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 4.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 2.1 GO:0000815 ESCRT III complex(GO:0000815)
0.2 4.2 GO:0071437 invadopodium(GO:0071437)
0.2 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 4.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.8 GO:0005883 neurofilament(GO:0005883)
0.1 1.7 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 3.2 GO:0044292 dendrite terminus(GO:0044292)
0.1 3.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 3.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 10.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 4.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 4.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 5.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.7 GO:0004359 glutaminase activity(GO:0004359)
0.7 4.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.6 3.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.9 GO:0019809 spermidine binding(GO:0019809)
0.4 1.2 GO:0004802 transketolase activity(GO:0004802)
0.3 1.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 3.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 3.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 3.1 GO:0005522 profilin binding(GO:0005522)
0.1 3.1 GO:0031489 myosin V binding(GO:0031489)
0.1 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 4.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 4.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 6.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 4.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.5 GO:0030276 clathrin binding(GO:0030276)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 13.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 4.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 4.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA