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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Myod1

Z-value: 2.44

Motif logo

Transcription factors associated with Myod1

Gene Symbol Gene ID Gene Info
ENSMUSG00000009471.5 Myod1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Myod1mm39_v1_chr7_+_46025890_460259040.855.8e-21Click!

Activity profile of Myod1 motif

Sorted Z-values of Myod1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Myod1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_23629173 32.14 ENSMUST00000174435.2
ankyrin 1, erythroid
chr8_+_23629046 30.87 ENSMUST00000121075.8
ankyrin 1, erythroid
chr8_+_23629080 30.65 ENSMUST00000033947.15
ankyrin 1, erythroid
chr7_+_126811831 27.25 ENSMUST00000127710.3
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_43523388 26.67 ENSMUST00000107913.10
ENSMUST00000030184.12
tropomyosin 2, beta
chr4_-_43523745 26.00 ENSMUST00000150592.2
tropomyosin 2, beta
chr2_-_52225763 25.99 ENSMUST00000238288.2
ENSMUST00000238749.2
nebulin
chr2_+_152753231 24.22 ENSMUST00000028970.8
myosin, light polypeptide kinase 2, skeletal muscle
chr7_+_141995545 23.90 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr4_-_43523595 22.26 ENSMUST00000107914.10
tropomyosin 2, beta
chr7_+_126810780 22.24 ENSMUST00000032910.13
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_+_19144950 22.22 ENSMUST00000208710.2
ENSMUST00000003643.3
creatine kinase, muscle
chr2_-_113883285 21.66 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr6_-_97229708 20.37 ENSMUST00000095655.4
leiomodin 3 (fetal)
chr8_+_55003359 20.35 ENSMUST00000033918.4
ankyrin repeat and SOCs box-containing 5
chr7_-_140480314 20.33 ENSMUST00000026561.10
cytochrome c oxidase subunit 8B
chr1_+_75336965 18.15 ENSMUST00000027409.10
desmin
chr18_-_60724855 17.86 ENSMUST00000056533.9
myozenin 3
chr7_+_45289391 17.78 ENSMUST00000148532.4
MEF2 activating motif and SAP domain containing transcriptional regulator
chr11_+_82802079 17.17 ENSMUST00000018989.14
ENSMUST00000164945.3
unc-45 myosin chaperone B
chr7_-_126046814 17.12 ENSMUST00000146973.2
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr17_-_48739874 16.65 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr7_+_141996067 15.66 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr3_-_116601451 15.15 ENSMUST00000159670.3
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr7_-_44174065 15.01 ENSMUST00000165208.4
myosin binding protein C, fast-type
chr11_-_120441952 13.91 ENSMUST00000026121.3
protein phosphatase 1, regulatory subunit 27
chr2_-_164621641 13.58 ENSMUST00000103095.5
troponin C2, fast
chr15_-_76906832 13.03 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr9_+_121606750 12.97 ENSMUST00000098272.4
kelch-like 40
chr3_-_116601700 12.78 ENSMUST00000159742.8
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr2_-_52225146 12.68 ENSMUST00000075301.10
nebulin
chr3_-_116601815 12.64 ENSMUST00000040603.14
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chrX_+_100492684 12.62 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr13_+_46571910 12.36 ENSMUST00000037923.5
RNA binding motif protein 24
chr11_-_107607343 12.14 ENSMUST00000021065.6
calcium channel, voltage-dependent, gamma subunit 1
chr9_-_50663571 11.84 ENSMUST00000042790.5
heat shock protein 2
chrX_+_21581135 11.62 ENSMUST00000033414.8
solute carrier family 6 (neurotransmitter transporter), member 14
chr3_+_102981326 11.55 ENSMUST00000090715.13
ENSMUST00000155034.6
adenosine monophosphate deaminase 1
chr9_-_121621544 11.32 ENSMUST00000035110.11
hedgehog acyltransferase-like
chr10_-_80649315 11.31 ENSMUST00000181039.8
ENSMUST00000180438.2
junctional sarcoplasmic reticulum protein 1
chr1_+_135980639 11.24 ENSMUST00000112064.8
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_135980488 11.23 ENSMUST00000160641.8
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr17_-_27386763 11.22 ENSMUST00000025046.4
inositol hexaphosphate kinase 3
chr1_+_135980508 11.17 ENSMUST00000112068.10
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr4_+_129181407 11.11 ENSMUST00000102599.4
syncoilin
chr11_-_5753693 11.11 ENSMUST00000020768.4
phosphoglycerate mutase 2
chr9_+_50664288 11.06 ENSMUST00000214962.2
ENSMUST00000216755.2
crystallin, alpha B
chr16_+_87350202 11.06 ENSMUST00000026700.8
Map3k7 C-terminal like
chr17_-_67939702 11.05 ENSMUST00000097290.4
leucine rich repeat containing 30
chr14_+_55813074 10.81 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr15_-_75620060 10.79 ENSMUST00000062002.6
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr1_-_74788013 10.79 ENSMUST00000188073.7
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr8_+_46338557 10.60 ENSMUST00000210422.2
PDZ and LIM domain 3
chr5_-_69699965 10.37 ENSMUST00000031045.10
Yip1 domain family, member 7
chr11_-_3477916 10.14 ENSMUST00000020718.10
smoothelin
chr9_-_50663648 10.07 ENSMUST00000217159.2
heat shock protein 2
chr3_+_102981352 10.01 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr2_+_90865958 9.96 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
receptor-associated protein of the synapse
chr6_+_17307272 9.69 ENSMUST00000115454.2
caveolin 1, caveolae protein
chr9_-_119852624 9.52 ENSMUST00000111635.4
xin actin-binding repeat containing 1
chr8_+_46338498 9.44 ENSMUST00000034053.7
PDZ and LIM domain 3
chr9_+_50664207 9.31 ENSMUST00000034562.9
crystallin, alpha B
chr14_-_21798678 9.29 ENSMUST00000075040.9
dual specificity phosphatase 13
chr2_-_84652890 9.27 ENSMUST00000028471.6
smoothelin-like 1
chr3_-_151971391 9.13 ENSMUST00000199470.5
ENSMUST00000200589.5
nexilin
chr11_+_117700479 9.04 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
synaptogyrin 2
predicted gene 20708
chr2_-_76812799 9.02 ENSMUST00000011934.13
ENSMUST00000099981.10
ENSMUST00000099980.10
ENSMUST00000111882.9
ENSMUST00000140091.8
titin
chr5_-_69699932 8.80 ENSMUST00000202423.2
Yip1 domain family, member 7
chr11_+_69856222 8.65 ENSMUST00000018713.13
claudin 7
chr10_-_81037878 8.58 ENSMUST00000005069.8
nicotinamide riboside kinase 2
chr6_-_71239216 8.51 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr7_+_28533279 8.32 ENSMUST00000208971.2
ENSMUST00000066723.15
lectin, galactose binding, soluble 4
chr6_+_17307639 8.22 ENSMUST00000115453.2
caveolin 1, caveolae protein
chr10_+_116822219 8.18 ENSMUST00000020378.5
bestrophin 3
chr2_-_120370333 8.16 ENSMUST00000171215.8
zinc finger protein 106
chr2_-_73410632 7.97 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr15_-_58078274 7.76 ENSMUST00000022986.8
F-box protein 32
chr11_-_59029996 7.73 ENSMUST00000219084.3
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr11_-_120538928 7.52 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr2_-_125348305 7.51 ENSMUST00000028633.13
fibrillin 1
chr10_+_127337541 7.46 ENSMUST00000160019.8
ENSMUST00000160610.2
ENSMUST00000035839.3
SH3 and cysteine rich domain 3
chr7_+_27770655 7.22 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr8_-_106198112 7.20 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr11_+_48728291 7.17 ENSMUST00000046903.6
tripartite motif-containing 7
chr14_+_30601157 7.11 ENSMUST00000040715.8
musculoskeletal, embryonic nuclear protein 1
chr14_-_21798694 6.95 ENSMUST00000183943.2
dual specificity phosphatase 13
chr7_+_43874854 6.94 ENSMUST00000206144.2
kallikrein 1
chr10_+_3316505 6.90 ENSMUST00000217573.2
protein phosphatase 1, regulatory inhibitor subunit 14C
chr14_-_20714634 6.86 ENSMUST00000119483.2
synaptopodin 2-like
chr11_+_110956980 6.72 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr19_+_47167554 6.72 ENSMUST00000235290.2
neuralized E3 ubiquitin protein ligase 1A
chr9_+_43978290 6.70 ENSMUST00000034508.14
ubiquitin specific peptidase 2
chr5_-_134776101 6.66 ENSMUST00000015138.13
elastin
chr15_-_96953823 6.45 ENSMUST00000023101.10
solute carrier family 38, member 4
chr11_+_96820220 6.28 ENSMUST00000062172.6
proline rich 15-like
chr8_-_120362291 6.26 ENSMUST00000061828.10
potassium voltage-gated channel, subfamily G, member 4
chr3_-_19319123 6.23 ENSMUST00000121951.2
phosphodiesterase 7A
chr19_+_5118103 6.21 ENSMUST00000070630.8
CD248 antigen, endosialin
chr6_-_88604404 6.06 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr19_+_7034149 6.05 ENSMUST00000040261.7
mono-ADP ribosylhydrolase 1
chr3_+_60408600 5.96 ENSMUST00000099087.8
muscleblind like splicing factor 1
chr1_-_44258112 5.93 ENSMUST00000054801.4
methyltransferase like 21E
chr8_-_120362085 5.92 ENSMUST00000164382.2
potassium voltage-gated channel, subfamily G, member 4
chrX_-_73325318 5.85 ENSMUST00000239458.2
ENSMUST00000019232.10
deoxyribonuclease 1-like 1
chr2_+_153334710 5.83 ENSMUST00000109783.2
RIKEN cDNA 4930404H24 gene
chr16_+_57173632 5.64 ENSMUST00000099667.3
filamin A interacting protein 1-like
chr4_-_104967032 5.64 ENSMUST00000030243.8
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr15_+_78810919 5.64 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chr11_+_96820091 5.56 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr18_+_36481792 5.56 ENSMUST00000152804.9
cysteine-rich transmembrane module containing 1
chr10_+_36383008 5.55 ENSMUST00000168572.8
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr11_+_77353218 5.46 ENSMUST00000102493.8
coronin 6
chr18_+_36481706 5.43 ENSMUST00000235864.2
ENSMUST00000050584.10
cysteine-rich transmembrane module containing 1
chr9_+_43978369 5.28 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chrX_-_73325204 5.23 ENSMUST00000114189.10
ENSMUST00000119361.4
deoxyribonuclease 1-like 1
chr4_-_141351110 5.15 ENSMUST00000038661.8
solute carrier family 25, member 34
chr10_-_23226034 5.14 ENSMUST00000219315.2
EYA transcriptional coactivator and phosphatase 4
chr19_+_47167259 5.03 ENSMUST00000111808.11
neuralized E3 ubiquitin protein ligase 1A
chr4_+_135487016 5.02 ENSMUST00000105854.2
myomesin family, member 3
chr11_+_87989972 5.00 ENSMUST00000018522.13
CUE domain containing 1
chr12_+_33004178 4.92 ENSMUST00000020885.13
synaptophysin-like protein
chr1_+_40720731 4.87 ENSMUST00000192345.2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr11_+_106256298 4.84 ENSMUST00000009354.10
proline rich 29
chr3_-_144425819 4.84 ENSMUST00000199531.5
ENSMUST00000199854.5
SH3-domain GRB2-like B1 (endophilin)
chr11_-_70510010 4.83 ENSMUST00000102556.10
ENSMUST00000014753.9
cholinergic receptor, nicotinic, epsilon polypeptide
chr13_-_49301407 4.79 ENSMUST00000162581.8
ENSMUST00000110097.9
ENSMUST00000049265.15
ENSMUST00000035538.13
ENSMUST00000110096.8
ENSMUST00000091623.10
WNK lysine deficient protein kinase 2
chr7_+_99659121 4.74 ENSMUST00000107084.8
chordin-like 2
chr7_+_130294262 4.61 ENSMUST00000033141.7
transforming, acidic coiled-coil containing protein 2
chr6_+_17307038 4.61 ENSMUST00000123439.8
caveolin 1, caveolae protein
chr17_+_48047955 4.54 ENSMUST00000086932.10
transcription factor EB
chr7_-_27010068 4.49 ENSMUST00000125455.2
latent transforming growth factor beta binding protein 4
chr13_-_60325170 4.49 ENSMUST00000065086.6
growth arrest specific 1
chr9_-_58066484 4.39 ENSMUST00000041477.15
immunoglobulin superfamily containing leucine-rich repeat
chr3_-_63391300 4.36 ENSMUST00000192926.2
small transmembrane regulator of ion transport 1
chr1_+_165288606 4.36 ENSMUST00000027853.6
mitochondrial pyruvate carrier 2
chr16_+_57173456 4.35 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr6_-_52168675 4.33 ENSMUST00000101395.3
homeobox A4
chr9_-_79884920 4.32 ENSMUST00000239133.2
filamin A interacting protein 1
chr7_+_130294403 4.31 ENSMUST00000207282.2
transforming, acidic coiled-coil containing protein 2
chr2_+_122479770 4.31 ENSMUST00000047498.15
ENSMUST00000110512.4
expressed sequence AA467197
chr11_-_54968901 4.30 ENSMUST00000055040.13
coiled-coil domain containing 69
chr8_-_123187406 4.30 ENSMUST00000006762.7
snail family zinc finger 3
chr6_-_124817155 4.22 ENSMUST00000024206.6
guanine nucleotide binding protein (G protein), beta 3
chr9_-_79885063 4.20 ENSMUST00000093811.11
filamin A interacting protein 1
chr11_-_69496655 4.18 ENSMUST00000047889.13
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_+_101916992 4.17 ENSMUST00000033289.6
ENSMUST00000209255.2
stromal interaction molecule 1
chr8_+_120121612 4.16 ENSMUST00000098367.5
malonyl-CoA decarboxylase
chr3_+_60408678 4.14 ENSMUST00000191747.6
ENSMUST00000194069.6
muscleblind like splicing factor 1
chr1_-_75195889 4.12 ENSMUST00000186213.7
tubulin, alpha 4A
chr1_-_75482975 4.07 ENSMUST00000113567.10
ENSMUST00000113565.3
obscurin-like 1
chr11_-_101315345 4.04 ENSMUST00000107257.8
ENSMUST00000107259.4
ENSMUST00000107252.9
ENSMUST00000093933.11
predicted gene, 27029
prostaglandin E synthase 3 like
chr6_-_99643723 4.04 ENSMUST00000032151.3
eukaryotic translation initiation factor 4E member 3
chr15_+_99615396 3.99 ENSMUST00000023760.13
ENSMUST00000162194.2
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr8_+_106245368 3.97 ENSMUST00000034363.7
hydroxysteroid 11-beta dehydrogenase 2
chr7_+_142025575 3.97 ENSMUST00000038946.9
lymphocyte specific 1
chr7_+_3339059 3.94 ENSMUST00000096744.8
myeloid-associated differentiation marker
chr1_+_87118346 3.91 ENSMUST00000073252.9
cholinergic receptor, nicotinic, delta polypeptide
chr18_+_32055339 3.88 ENSMUST00000233994.2
LIM and senescent cell antigen like domains 2
chr7_+_3339077 3.87 ENSMUST00000203566.3
myeloid-associated differentiation marker
chr9_+_30853837 3.81 ENSMUST00000068135.13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr8_-_62355690 3.77 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr12_+_113104085 3.77 ENSMUST00000200380.5
cysteine rich protein 2
chr18_+_32510270 3.74 ENSMUST00000234857.2
ENSMUST00000234496.2
ENSMUST00000091967.13
ENSMUST00000025239.9
bridging integrator 1
chr12_+_113103817 3.72 ENSMUST00000084882.9
cysteine rich protein 2
chr14_+_67470884 3.62 ENSMUST00000176161.8
early B cell factor 2
chr6_+_112250719 3.62 ENSMUST00000032376.6
LIM and cysteine-rich domains 1
chr19_+_47167444 3.56 ENSMUST00000235326.2
neuralized E3 ubiquitin protein ligase 1A
chr2_-_84605732 3.53 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_131021905 3.52 ENSMUST00000089510.5
centromere protein B
chr4_-_107889136 3.52 ENSMUST00000106708.8
podocan
chrX_-_51702790 3.52 ENSMUST00000069360.14
glypican 3
chr11_-_96714813 3.50 ENSMUST00000142065.2
ENSMUST00000167110.8
nuclear factor, erythroid derived 2,-like 1
chr18_+_61096597 3.50 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr19_-_45548942 3.50 ENSMUST00000026239.7
polymerase (DNA directed), lambda
chr2_-_84605764 3.50 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_-_58065800 3.49 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr4_+_58285957 3.46 ENSMUST00000081919.12
ENSMUST00000177951.8
ENSMUST00000098059.10
ENSMUST00000179951.2
ENSMUST00000102893.10
ENSMUST00000084578.12
ENSMUST00000098057.10
muscle, skeletal, receptor tyrosine kinase
chr10_-_120037464 3.44 ENSMUST00000020448.11
interleukin-1 receptor-associated kinase 3
chrX_+_139857640 3.43 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr11_-_20781009 3.40 ENSMUST00000047028.9
lectin, galactoside binding-like
chr7_+_142025817 3.40 ENSMUST00000105966.2
lymphocyte specific 1
chr13_+_83652352 3.39 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr1_+_135764092 3.39 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr12_-_86125793 3.36 ENSMUST00000003687.8
transforming growth factor, beta 3
chr1_-_135302971 3.33 ENSMUST00000041240.4
shisa family member 4
chr8_-_112417633 3.32 ENSMUST00000034435.7
chymotrypsinogen B1
chr12_-_76756772 3.30 ENSMUST00000166101.2
spectrin beta, erythrocytic
chrX_-_51702813 3.29 ENSMUST00000114857.2
glypican 3
chr2_-_26962187 3.27 ENSMUST00000009358.9
myomaker, myoblast fusion factor
chr11_+_50492899 3.25 ENSMUST00000142118.3
ENSMUST00000040523.9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr16_+_6887689 3.21 ENSMUST00000229741.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_+_67470735 3.20 ENSMUST00000022637.14
early B cell factor 2
chr13_+_83652150 3.17 ENSMUST00000198199.5
myocyte enhancer factor 2C
chr1_-_172460497 3.16 ENSMUST00000027826.7
dual specificity phosphatase 23
chrX_+_139857688 3.12 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr8_+_96078886 3.11 ENSMUST00000034243.7
matrix metallopeptidase 15
chr11_+_102727122 3.08 ENSMUST00000021302.15
ENSMUST00000107072.2
HIG1 domain family, member 1B
chr2_-_62313981 3.01 ENSMUST00000136686.2
ENSMUST00000102733.10
glucagon
chr4_+_15265798 3.00 ENSMUST00000062684.9
transmembrane protein 64
chr3_+_89344006 2.96 ENSMUST00000038942.10
ENSMUST00000130858.8
ENSMUST00000146630.8
ENSMUST00000145753.2
pre B cell leukemia transcription factor interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 41.3 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
6.7 6.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
4.6 51.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
3.8 11.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
3.8 22.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
3.7 33.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
2.6 7.8 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.5 7.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
2.3 7.0 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.2 21.6 GO:0032264 IMP salvage(GO:0032264)
2.1 8.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
2.1 96.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.9 21.3 GO:0007525 somatic muscle development(GO:0007525)
1.9 5.6 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.9 11.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.8 19.6 GO:0007021 tubulin complex assembly(GO:0007021)
1.8 91.2 GO:0003009 skeletal muscle contraction(GO:0003009)
1.7 19.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.5 38.3 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
1.5 4.4 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.4 13.0 GO:0015671 oxygen transport(GO:0015671)
1.4 13.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.4 4.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
1.4 6.8 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
1.4 10.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.3 4.0 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
1.3 7.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.3 20.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.2 3.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.2 5.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.1 4.5 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
1.1 3.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 3.4 GO:0003032 detection of oxygen(GO:0003032)
1.1 3.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
1.1 4.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
1.0 4.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.0 2.9 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
1.0 13.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.9 6.5 GO:0051697 protein delipidation(GO:0051697)
0.9 3.7 GO:0060988 lipid tube assembly(GO:0060988)
0.9 9.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.9 1.8 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.9 7.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.9 6.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.9 12.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.8 4.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 3.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.8 57.7 GO:0045214 sarcomere organization(GO:0045214)
0.8 4.7 GO:0006116 NADH oxidation(GO:0006116)
0.8 2.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.8 3.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.7 1.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.7 9.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.7 5.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.7 12.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.7 5.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7 2.0 GO:0051542 elastin biosynthetic process(GO:0051542)
0.6 2.6 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.6 4.9 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.6 1.8 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.6 1.8 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.6 2.9 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.6 3.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 6.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.6 3.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.6 12.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.6 1.7 GO:0002663 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) endocardial cushion fusion(GO:0003274)
0.6 3.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.6 1.7 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.6 1.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.5 1.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.5 2.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.5 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.5 2.7 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.5 17.9 GO:0045109 intermediate filament organization(GO:0045109)
0.5 4.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.5 3.6 GO:0003383 apical constriction(GO:0003383)
0.5 2.1 GO:0046340 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.5 24.5 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.5 12.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.5 8.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.5 14.9 GO:0014823 response to activity(GO:0014823)
0.4 12.1 GO:0030239 myofibril assembly(GO:0030239)
0.4 2.7 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 1.3 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.4 2.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.4 2.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.4 4.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 2.0 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 2.4 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957)
0.4 2.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 2.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 2.7 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.4 1.9 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.4 10.8 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.4 8.9 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.4 1.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.4 1.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 3.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 3.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 4.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3 11.1 GO:0006308 DNA catabolic process(GO:0006308)
0.3 4.5 GO:0042473 outer ear morphogenesis(GO:0042473)
0.3 9.5 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.3 0.6 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 67.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.3 2.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 6.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 0.3 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.3 0.9 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 6.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.3 0.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
0.3 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 2.5 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 0.8 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 4.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 0.8 GO:0071846 actin filament debranching(GO:0071846)
0.3 0.8 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.3 10.8 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.3 10.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 3.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 12.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 1.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 1.7 GO:0051541 elastin metabolic process(GO:0051541) elastin catabolic process(GO:0060309)
0.2 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 1.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 0.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2 3.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.9 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.5 GO:0051450 myoblast proliferation(GO:0051450)
0.2 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.6 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) positive regulation of hindgut contraction(GO:0060450) regulation of relaxation of smooth muscle(GO:1901080) positive regulation of relaxation of smooth muscle(GO:1901082)
0.2 2.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 2.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 4.7 GO:0030574 collagen catabolic process(GO:0030574)
0.2 17.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 1.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.2 1.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 58.3 GO:0006936 muscle contraction(GO:0006936)
0.2 4.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 3.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.5 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.2 0.8 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 1.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 0.5 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.2 2.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.2 0.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 8.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.9 GO:0042637 catagen(GO:0042637)
0.1 2.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 1.0 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.1 0.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.5 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 1.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.5 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 1.6 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0019087 negative regulation of fibroblast migration(GO:0010764) transformation of host cell by virus(GO:0019087)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 2.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 1.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 1.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 4.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 7.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.6 GO:0046541 saliva secretion(GO:0046541)
0.1 1.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 1.2 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 4.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.1 2.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.6 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.3 GO:0060538 skeletal muscle organ development(GO:0060538)
0.1 1.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 5.7 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.1 1.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 1.6 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.1 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.5 GO:1901142 insulin metabolic process(GO:1901142)
0.1 0.4 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 0.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 4.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 7.6 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 2.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 5.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 3.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 2.2 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 2.8 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 1.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 10.6 GO:0006520 cellular amino acid metabolic process(GO:0006520)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 2.5 GO:0001657 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 3.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0010543 regulation of platelet activation(GO:0010543)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 3.9 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.7 GO:0007569 cell aging(GO:0007569)
0.0 8.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 1.9 GO:0007586 digestion(GO:0007586)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 1.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:0042643 actomyosin, actin portion(GO:0042643)
5.1 76.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
3.6 18.2 GO:0097512 cardiac myofibril(GO:0097512)
3.6 183.2 GO:0031430 M band(GO:0031430)
3.0 56.5 GO:0005861 troponin complex(GO:0005861)
2.3 38.7 GO:0005865 striated muscle thin filament(GO:0005865)
2.1 17.1 GO:0031673 H zone(GO:0031673)
1.3 6.7 GO:0071953 elastic fiber(GO:0071953)
1.3 22.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.3 24.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.1 4.6 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
1.0 2.9 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.8 17.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.8 84.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.8 2.3 GO:0031904 endosome lumen(GO:0031904)
0.6 5.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.6 13.8 GO:0031672 A band(GO:0031672)
0.6 7.2 GO:0097427 microtubule bundle(GO:0097427)
0.5 3.3 GO:0008091 spectrin(GO:0008091)
0.5 2.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5 6.9 GO:0005916 fascia adherens(GO:0005916)
0.5 83.4 GO:0030018 Z disc(GO:0030018)
0.5 16.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 7.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.5 35.7 GO:0016459 myosin complex(GO:0016459)
0.5 3.6 GO:0033269 internode region of axon(GO:0033269)
0.4 10.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 4.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 2.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 2.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 8.2 GO:0000421 autophagosome membrane(GO:0000421)
0.3 11.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 3.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 9.1 GO:0030017 sarcomere(GO:0030017)
0.2 6.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.2 2.7 GO:0045180 basal cortex(GO:0045180)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 3.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 7.5 GO:0097440 apical dendrite(GO:0097440)
0.2 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 11.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 4.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 5.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 4.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 8.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 2.1 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 7.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 13.9 GO:0005938 cell cortex(GO:0005938)
0.1 5.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.3 GO:0005884 actin filament(GO:0005884)
0.0 2.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0030689 Noc complex(GO:0030689)
0.0 6.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 12.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 8.3 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 4.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0043292 contractile fiber(GO:0043292)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.5 40.6 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
9.4 93.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
4.0 39.6 GO:0031014 troponin T binding(GO:0031014)
3.8 15.3 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
3.8 22.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
3.7 11.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
3.6 17.9 GO:0051373 FATZ binding(GO:0051373)
3.5 24.2 GO:0032027 myosin light chain binding(GO:0032027)
3.2 22.2 GO:0004111 creatine kinase activity(GO:0004111)
2.9 8.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
2.7 185.3 GO:0008307 structural constituent of muscle(GO:0008307)
2.3 11.6 GO:0005275 amine transmembrane transporter activity(GO:0005275)
2.2 21.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.9 11.2 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.9 16.7 GO:0004126 cytidine deaminase activity(GO:0004126)
1.6 4.9 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
1.6 33.9 GO:0005523 tropomyosin binding(GO:0005523)
1.5 9.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.4 13.0 GO:0005344 oxygen transporter activity(GO:0005344)
1.4 5.6 GO:0048030 disaccharide binding(GO:0048030)
1.3 4.0 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.3 4.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.3 42.3 GO:0005212 structural constituent of eye lens(GO:0005212)
1.3 17.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
1.2 31.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.0 8.2 GO:0001515 opioid peptide activity(GO:0001515)
0.9 8.3 GO:0016936 galactoside binding(GO:0016936)
0.9 3.5 GO:0003696 satellite DNA binding(GO:0003696)
0.9 7.7 GO:0031432 titin binding(GO:0031432)
0.9 6.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9 17.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.8 24.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.8 5.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.8 0.8 GO:0050436 microfibril binding(GO:0050436)
0.8 2.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 10.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.7 2.7 GO:0043532 angiostatin binding(GO:0043532)
0.7 3.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.7 4.0 GO:0032810 sterol response element binding(GO:0032810)
0.6 4.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 1.8 GO:0070540 stearic acid binding(GO:0070540)
0.6 13.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 10.0 GO:0043495 protein anchor(GO:0043495)
0.5 3.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 3.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 4.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.5 7.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.5 1.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 10.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 1.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.4 3.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 4.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 9.1 GO:0003680 AT DNA binding(GO:0003680)
0.4 2.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 1.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 11.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 21.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 9.5 GO:0031005 filamin binding(GO:0031005)
0.3 0.9 GO:0016015 morphogen activity(GO:0016015)
0.3 2.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 4.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 17.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 2.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 7.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.3 2.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.3 12.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 1.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 7.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 12.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 9.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 5.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 2.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 5.4 GO:0001848 complement binding(GO:0001848)
0.2 6.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.0 GO:1990254 keratin filament binding(GO:1990254)
0.2 1.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 15.3 GO:0017022 myosin binding(GO:0017022)
0.2 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 3.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 9.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 2.7 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 3.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 7.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 3.7 GO:0048156 tau protein binding(GO:0048156)
0.1 14.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 11.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 2.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 3.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 8.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 2.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 4.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 8.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.5 GO:0030332 cyclin binding(GO:0030332)
0.1 7.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.3 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 4.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 14.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 9.0 GO:0005178 integrin binding(GO:0005178)
0.1 12.0 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 5.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 1.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 6.2 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 14.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 6.5 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.3 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 1.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 10.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 6.6 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 23.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.5 19.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.3 7.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 7.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 15.0 PID AURORA B PATHWAY Aurora B signaling
0.3 52.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 8.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 7.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 5.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 2.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 7.8 PID FOXO PATHWAY FoxO family signaling
0.2 15.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 18.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 9.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 2.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 5.1 PID ALK1 PATHWAY ALK1 signaling events
0.2 2.7 PID IL5 PATHWAY IL5-mediated signaling events
0.2 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 5.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 3.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 10.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 201.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.9 39.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.7 86.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.2 17.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
1.0 13.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9 27.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.9 21.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.9 21.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.5 17.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 11.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5 31.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 17.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 7.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 12.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 6.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 11.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 6.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 7.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 2.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.0 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 6.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 5.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 5.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 5.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 4.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 5.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 5.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 11.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication