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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfat5

Z-value: 0.99

Motif logo

Transcription factors associated with Nfat5

Gene Symbol Gene ID Gene Info
ENSMUSG00000003847.17 Nfat5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfat5mm39_v1_chr8_+_108020132_108020191-0.334.7e-03Click!

Activity profile of Nfat5 motif

Sorted Z-values of Nfat5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_129548954 9.09 ENSMUST00000029653.7
epidermal growth factor
chr12_+_36042899 6.65 ENSMUST00000020898.12
anterior gradient 2
chr11_-_99383938 6.27 ENSMUST00000006969.8
keratin 23
chr8_-_108129829 5.70 ENSMUST00000003947.9
NAD(P)H dehydrogenase, quinone 1
chr15_+_99476935 5.54 ENSMUST00000023752.6
aquaporin 2
chr1_+_87983099 5.19 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr11_+_83741657 4.89 ENSMUST00000021016.10
HNF1 homeobox B
chr11_+_83741689 4.50 ENSMUST00000108114.9
HNF1 homeobox B
chr3_-_98631847 4.50 ENSMUST00000107021.8
ENSMUST00000107022.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr7_-_80052491 4.42 ENSMUST00000122232.8
furin (paired basic amino acid cleaving enzyme)
chr17_-_34694911 4.31 ENSMUST00000065841.5
butyrophilin-like 4
chr1_+_88334678 4.25 ENSMUST00000027518.12
secreted phosphoprotein 2
chr17_-_34736326 4.07 ENSMUST00000075483.5
butyrophilin-like 6
chr1_+_87983189 3.86 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr19_+_25214322 3.74 ENSMUST00000049400.15
KN motif and ankyrin repeat domains 1
chr19_-_7688628 3.73 ENSMUST00000025666.8
solute carrier family 22 (organic anion transporter), member 19
chr15_-_75766321 3.51 ENSMUST00000023237.8
nicotinate phosphoribosyltransferase
chr11_+_120382666 3.23 ENSMUST00000026899.4
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr7_+_140658101 3.19 ENSMUST00000106039.9
plakophilin 3
chr10_+_21870565 3.16 ENSMUST00000020145.12
serum/glucocorticoid regulated kinase 1
chr15_-_57128522 2.98 ENSMUST00000137764.2
ENSMUST00000022995.13
solute carrier family 22 (organic cation transporter), member 22
chr15_+_25933632 2.87 ENSMUST00000228327.2
reticulophagy regulator 1
chr6_+_48849804 2.69 ENSMUST00000204856.2
amine oxidase, copper-containing 1
chr4_-_82423985 2.68 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr11_-_88754543 2.63 ENSMUST00000107904.3
A kinase (PRKA) anchor protein 1
chr18_-_78640066 2.62 ENSMUST00000235389.2
ENSMUST00000237674.2
solute carrier family 14 (urea transporter), member 2
chr10_+_21869776 2.61 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr2_-_30305472 2.51 ENSMUST00000134120.2
ENSMUST00000102854.10
carnitine acetyltransferase
chr7_+_19753097 2.45 ENSMUST00000117909.2
NLR family, pyrin domain containing 9B
chr14_-_4808744 2.26 ENSMUST00000022303.17
ENSMUST00000091471.12
thyroid hormone receptor beta
chr6_+_91661034 2.26 ENSMUST00000032185.9
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr5_-_104169696 2.25 ENSMUST00000119025.2
hydroxysteroid (17-beta) dehydrogenase 11
chr9_-_36549886 2.21 ENSMUST00000093868.9
ENSMUST00000184611.2
prostate and testis expressed 14
chr3_-_27764571 2.20 ENSMUST00000046157.10
fibronectin type III domain containing 3B
chr10_+_5589210 2.20 ENSMUST00000019906.6
vasoactive intestinal polypeptide
chr1_-_93373145 2.15 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr10_-_95251327 2.15 ENSMUST00000172070.8
ENSMUST00000150432.8
suppressor of cytokine signaling 2
chr11_+_94172657 2.08 ENSMUST00000208510.3
predicted gene, 21885
chr6_-_101354858 2.07 ENSMUST00000075994.11
PDZ domain containing RING finger 3
chr5_-_104169785 2.05 ENSMUST00000031251.16
hydroxysteroid (17-beta) dehydrogenase 11
chrX_+_138585728 2.03 ENSMUST00000096313.4
TBC1 domain family, member 8B
chr3_+_91921890 2.02 ENSMUST00000047660.5
peptidoglycan recognition protein 3
chr6_+_91661074 2.01 ENSMUST00000205480.2
ENSMUST00000206545.2
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr11_+_9141934 1.99 ENSMUST00000042740.13
ATP-binding cassette, sub-family A (ABC1), member 13
chr10_-_95251145 1.97 ENSMUST00000119917.2
suppressor of cytokine signaling 2
chr11_+_118913788 1.94 ENSMUST00000026662.8
chromobox 2
chr7_+_19725390 1.90 ENSMUST00000207805.2
NLR family, pyrin domain containing 9B
chr8_-_106706035 1.90 ENSMUST00000034371.9
dipeptidase 3
chr2_-_30305313 1.86 ENSMUST00000132981.9
ENSMUST00000129494.2
carnitine acetyltransferase
chr7_+_46496929 1.85 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr6_+_92793440 1.84 ENSMUST00000057977.4
RIKEN cDNA A730049H05 gene
chr6_+_73225616 1.83 ENSMUST00000203632.2
succinate-CoA ligase, GDP-forming, alpha subunit
chr3_-_27764522 1.80 ENSMUST00000195008.6
fibronectin type III domain containing 3B
chr10_-_29411857 1.76 ENSMUST00000092623.5
R-spondin 3
chr2_+_172391501 1.74 ENSMUST00000030391.9
transcription factor AP-2, gamma
chr10_-_78188046 1.71 ENSMUST00000146899.2
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_19741948 1.70 ENSMUST00000073151.13
NLR family, pyrin domain containing 9B
chr16_-_16418397 1.69 ENSMUST00000159542.8
FYVE, RhoGEF and PH domain containing 4
chr18_+_61408073 1.62 ENSMUST00000135688.2
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_-_126224848 1.59 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr5_+_139408906 1.56 ENSMUST00000066211.5
G protein-coupled estrogen receptor 1
chr14_+_5894220 1.41 ENSMUST00000063750.8
retinoic acid receptor, beta
chr6_+_139564196 1.40 ENSMUST00000188066.2
ENSMUST00000190962.7
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr4_-_135300934 1.36 ENSMUST00000105855.2
grainyhead like transcription factor 3
chr10_-_125164399 1.34 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr4_-_49506538 1.33 ENSMUST00000043056.9
bile acid-Coenzyme A: amino acid N-acyltransferase
chr3_-_144804784 1.29 ENSMUST00000040465.11
ENSMUST00000198993.2
chloride channel accessory 2
chr13_+_19362068 1.29 ENSMUST00000103553.3
T cell receptor gamma, variable 7
chr11_+_95152355 1.26 ENSMUST00000021242.5
tachykinin 4
chr1_+_24717793 1.26 ENSMUST00000186190.2
LMBR1 domain containing 1
chr19_+_56414114 1.24 ENSMUST00000238892.2
caspase 7
chrX_+_72030945 1.22 ENSMUST00000164800.8
ENSMUST00000114546.9
zinc finger protein 185
chr14_+_63284438 1.16 ENSMUST00000067990.8
ENSMUST00000111203.2
defensin beta 42
chr11_-_118292678 1.16 ENSMUST00000106290.4
lectin, galactoside-binding, soluble, 3 binding protein
chr11_-_118292758 1.12 ENSMUST00000043722.10
lectin, galactoside-binding, soluble, 3 binding protein
chr1_+_165312738 1.11 ENSMUST00000111440.8
ENSMUST00000027852.15
ENSMUST00000111439.8
adenylate cyclase 10
chr7_+_46496552 1.11 ENSMUST00000005051.6
lactate dehydrogenase A
chr18_+_36693646 1.06 ENSMUST00000155329.9
ankyrin repeat and KH domain containing 1
chr1_+_180773462 1.05 ENSMUST00000160508.2
ENSMUST00000160536.2
transmembrane protein 63a
chr4_-_82423944 1.04 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr5_-_15083012 1.04 ENSMUST00000167908.2
predicted gene 17019
chr5_-_26263579 0.98 ENSMUST00000095004.4
predicted gene 7347
chr5_+_17578178 0.92 ENSMUST00000166086.3
spermatogenesis associated glutamate (E)-rich protein 4f2
chr5_-_26147379 0.89 ENSMUST00000196214.2
predicted gene, 21663
chr11_+_54261452 0.88 ENSMUST00000094193.3
meiotic kinetochore factor
chrX_-_16683578 0.88 ENSMUST00000040820.13
monoamine oxidase B
chr5_-_26326419 0.88 ENSMUST00000088236.5
predicted gene 10220
chr10_-_78187887 0.86 ENSMUST00000105388.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr5_-_26310360 0.85 ENSMUST00000063524.3
RIKEN cDNA 5031410I06 gene
chr5_-_15028949 0.84 ENSMUST00000096953.5
predicted gene 10354
chr8_-_129858142 0.83 ENSMUST00000108743.2
predicted gene 10999
chr9_+_3025417 0.82 ENSMUST00000075573.7
predicted gene 10717
chr5_-_26227914 0.80 ENSMUST00000072286.7
predicted gene 5862
chr12_-_83643964 0.79 ENSMUST00000048319.6
zinc finger, FYVE domain containing 1
chr2_+_36886739 0.79 ENSMUST00000069578.5
olfactory receptor 357
chr5_-_14964913 0.75 ENSMUST00000035980.9
predicted gene 9758
chr7_-_30298287 0.74 ENSMUST00000108150.2
zinc finger and BTB domain containing 32
chr15_+_8997480 0.73 ENSMUST00000227191.3
RAN binding protein 3-like
chr5_-_26177661 0.70 ENSMUST00000200447.2
predicted gene, 21680
chr5_-_26193648 0.70 ENSMUST00000191203.7
predicted gene, 21698
chr13_-_21327251 0.70 ENSMUST00000055298.6
olfactory receptor 1368
chr5_-_26244556 0.68 ENSMUST00000079447.4
spermatogenesis associated glutamate (E)-rich protein 4A
chr8_-_76133212 0.66 ENSMUST00000212864.2
predicted gene 10358
chr4_+_19575128 0.66 ENSMUST00000108253.8
ENSMUST00000029888.4
regulator of microtubule dynamics 1
chr18_+_57666852 0.66 ENSMUST00000079738.10
ENSMUST00000135806.8
ENSMUST00000127130.9
coiled-coil domain containing 192
chr13_+_27241551 0.65 ENSMUST00000110369.10
ENSMUST00000224228.2
ENSMUST00000018061.7
prolactin
chr19_+_34078333 0.64 ENSMUST00000025685.8
lipase, family member M
chr4_+_3940747 0.62 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chr12_-_83643883 0.61 ENSMUST00000221919.2
zinc finger, FYVE domain containing 1
chr5_-_26159415 0.60 ENSMUST00000162387.6
predicted gene, 21671
chrX_+_37861548 0.60 ENSMUST00000050744.6
RIKEN cDNA 6030498E09 gene
chr5_-_27706360 0.59 ENSMUST00000155721.2
ENSMUST00000053257.10
spermatogenesis associated glutamate (E)-rich protein 4B
chr2_+_176522933 0.59 ENSMUST00000126726.2
ENSMUST00000122218.9
predicted gene 14408
chr7_+_46496506 0.58 ENSMUST00000209984.2
lactate dehydrogenase A
chr13_-_120374288 0.57 ENSMUST00000179502.2
predicted gene, 21761
chr2_+_32127309 0.57 ENSMUST00000123740.3
protein-O-mannosyltransferase 1
chr15_-_38079089 0.56 ENSMUST00000110336.4
ubiquitin protein ligase E3 component n-recognin 5
chrX_-_93408176 0.55 ENSMUST00000239046.2
family with sequence similarity 90, member A1B
chr5_-_66775979 0.55 ENSMUST00000162382.8
ENSMUST00000159786.8
ENSMUST00000162349.8
ENSMUST00000087256.12
ENSMUST00000160103.8
ENSMUST00000160870.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr17_+_38950335 0.55 ENSMUST00000174742.3
exocrine gland secreted peptide 31
chr7_+_55889488 0.53 ENSMUST00000032633.12
ENSMUST00000155533.2
ENSMUST00000156886.8
oculocutaneous albinism II
chr11_-_77616103 0.50 ENSMUST00000078623.5
crystallin, beta A1
chr13_+_120616163 0.50 ENSMUST00000179071.2
predicted gene, 20767
chr6_-_42437951 0.49 ENSMUST00000090156.2
olfactory receptor 458
chr17_+_38865083 0.49 ENSMUST00000173055.3
ENSMUST00000178654.2
exocrine gland secreted peptide 34
chrY_+_2599099 0.47 ENSMUST00000163651.2
H2A histone family member L2C
chr1_+_192984278 0.45 ENSMUST00000016315.16
laminin, beta 3
chr13_+_120779103 0.45 ENSMUST00000178349.2
2-cell-stage, variable group, member 3
chr9_-_39694549 0.45 ENSMUST00000216458.3
olfactory receptor 968
chr19_-_10502468 0.43 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr5_-_66776095 0.43 ENSMUST00000162366.8
ENSMUST00000162994.8
ENSMUST00000159512.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chrX_+_125947591 0.43 ENSMUST00000096332.2
predicted gene 382
chr13_+_23343482 0.41 ENSMUST00000226845.2
ENSMUST00000228666.2
ENSMUST00000227388.2
vomeronasal 1 receptor 219
chr11_+_97206542 0.40 ENSMUST00000019026.10
ENSMUST00000132168.2
mitochondrial ribosomal protein L45
chr9_+_37714354 0.40 ENSMUST00000215287.2
olfactory receptor 876
chr2_+_85838122 0.39 ENSMUST00000062166.2
olfactory receptor 1032
chr13_+_33508060 0.38 ENSMUST00000075515.7
serine (or cysteine) peptidase inhibitor, clade B, member 9f
chr5_-_26294289 0.35 ENSMUST00000094946.5
predicted gene 10471
chr12_-_114579938 0.34 ENSMUST00000195469.6
ENSMUST00000109711.4
immunoglobulin heavy variable V1-12
chr2_-_30305401 0.33 ENSMUST00000142096.2
carnitine acetyltransferase
chr7_+_104963189 0.31 ENSMUST00000098153.3
olfactory receptor 689
chr12_+_98886826 0.31 ENSMUST00000085109.10
ENSMUST00000079146.13
tetratricopeptide repeat domain 8
chr14_+_51599213 0.29 ENSMUST00000162998.2
predicted gene 7247
chr19_-_10502546 0.28 ENSMUST00000237827.2
succinate dehydrogenase complex assembly factor 2
chr19_-_12219023 0.28 ENSMUST00000087818.2
olfactory receptor 262
chr8_-_70426910 0.28 ENSMUST00000116463.4
GATA zinc finger domain containing 2A
chr19_+_11863929 0.27 ENSMUST00000217281.2
olfactory receptor 1420
chr1_-_181841969 0.27 ENSMUST00000193074.6
ENAH actin regulator
chr7_+_104202091 0.26 ENSMUST00000098176.5
olfactory receptor 651
chr5_+_91175323 0.25 ENSMUST00000202724.4
ENSMUST00000041516.9
epithelial mitogen
chr3_+_101917455 0.24 ENSMUST00000066187.6
ENSMUST00000198675.2
nescient helix loop helix 2
chr10_-_78187545 0.24 ENSMUST00000105390.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr14_+_59716265 0.22 ENSMUST00000224893.2
calcium binding protein 39-like
chr11_-_78948432 0.20 ENSMUST00000129463.2
kinase suppressor of ras 1
chr18_-_62729391 0.19 ENSMUST00000076194.6
serine peptidase inhibitor, Kazal type 7 (putative)
chr2_-_88256367 0.19 ENSMUST00000102619.3
ENSMUST00000213190.2
olfactory receptor 1181
chr3_+_101917392 0.18 ENSMUST00000196324.2
nescient helix loop helix 2
chr10_-_78187524 0.18 ENSMUST00000166360.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_-_43840201 0.17 ENSMUST00000214281.2
olfactory receptor 157
chr2_-_89030312 0.17 ENSMUST00000214709.2
ENSMUST00000215987.2
ENSMUST00000215562.2
ENSMUST00000220416.2
ENSMUST00000216445.2
ENSMUST00000217601.2
olfactory receptor 1226
chr10_+_112001581 0.16 ENSMUST00000170013.2
calcyphosphine 2
chr11_-_55042529 0.15 ENSMUST00000020502.9
ENSMUST00000069816.6
solute carrier family 36 (proton/amino acid symporter), member 3
chr1_+_24717722 0.10 ENSMUST00000186096.7
LMBR1 domain containing 1
chr14_-_101846551 0.10 ENSMUST00000100340.4
TBC1 domain family, member 4
chr19_-_11848669 0.05 ENSMUST00000087857.3
olfactory receptor 1419
chr8_+_71047010 0.04 ENSMUST00000211117.2
myo-inositol 1-phosphate synthase A1
chr9_+_92339422 0.02 ENSMUST00000034941.9
phospholipid scramblase 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.4 GO:0061206 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
2.2 6.7 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.8 5.5 GO:0071288 cellular response to mercury ion(GO:0071288)
1.4 4.3 GO:0001762 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
1.2 3.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.1 9.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.1 4.4 GO:0090472 dibasic protein processing(GO:0090472)
1.1 4.3 GO:0006710 androgen catabolic process(GO:0006710)
0.9 3.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.9 2.7 GO:0015898 amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.8 3.2 GO:0015744 succinate transport(GO:0015744)
0.8 9.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 4.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.7 2.0 GO:0051710 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.7 4.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.6 3.0 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.5 3.2 GO:0002159 desmosome assembly(GO:0002159)
0.5 1.6 GO:2000724 response to mineralocorticoid(GO:0051385) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.5 3.7 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.4 2.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.4 1.7 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.4 2.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 5.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.4 3.5 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 2.9 GO:0061709 reticulophagy(GO:0061709)
0.3 2.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 1.1 GO:0038016 insulin receptor internalization(GO:0038016)
0.3 4.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.3 1.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.3 3.5 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 1.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 0.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 2.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.2 1.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.2 0.6 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.7 GO:0030035 microspike assembly(GO:0030035)
0.2 1.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.7 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 0.9 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.3 GO:0019530 taurine metabolic process(GO:0019530)
0.1 1.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 4.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.6 GO:0046037 GMP metabolic process(GO:0046037)
0.1 0.7 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 5.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 1.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 1.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 4.2 GO:0046849 bone remodeling(GO:0046849)
0.0 2.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 1.9 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 2.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 4.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 2.5 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.2 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.6 3.2 GO:0005914 spot adherens junction(GO:0005914)
0.2 4.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 1.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 1.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 3.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 4.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 6.3 GO:0005882 intermediate filament(GO:0005882)
0.0 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 4.3 GO:0005811 lipid particle(GO:0005811)
0.0 10.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 6.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 3.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 2.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.0 GO:0030175 filopodium(GO:0030175)
0.0 29.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.1 GO:0045178 basal part of cell(GO:0045178)
0.0 8.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0005369 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
1.2 4.7 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
1.2 3.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.1 3.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.0 5.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.9 2.7 GO:0052598 diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.8 5.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.7 5.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.7 4.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.6 4.5 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.6 1.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.5 1.6 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.4 2.6 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.4 9.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.0 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3 0.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 3.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 6.7 GO:0002162 dystroglycan binding(GO:0002162)
0.3 3.7 GO:0019534 toxin transporter activity(GO:0019534)
0.3 4.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 4.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 9.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.2 3.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 2.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 2.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 3.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.0 GO:0005186 pheromone activity(GO:0005186)
0.1 1.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 3.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 9.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 9.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.8 PID FOXO PATHWAY FoxO family signaling
0.1 3.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 4.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 9.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 4.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 4.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 9.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 2.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 4.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1