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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfatc1

Z-value: 1.82

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000033016.17 Nfatc1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1mm39_v1_chr18_-_80751327_807513950.741.7e-13Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_88675700 11.62 ENSMUST00000087033.6
immunoglobulin joining chain
chr2_+_35172392 11.56 ENSMUST00000028239.8
gelsolin
chr17_-_48739874 10.92 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr3_-_106126794 10.38 ENSMUST00000082219.6
chitinase-like 4
chr15_-_41733099 10.25 ENSMUST00000054742.7
actin-binding Rho activating protein
chr4_-_43523595 9.72 ENSMUST00000107914.10
tropomyosin 2, beta
chr15_+_78810919 9.18 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chr1_+_75336965 9.14 ENSMUST00000027409.10
desmin
chr12_-_101784727 8.40 ENSMUST00000222587.2
fibulin 5
chr15_-_83135920 8.10 ENSMUST00000229687.2
ENSMUST00000164614.3
ENSMUST00000049530.14
alpha 1,4-galactosyltransferase
chr18_-_80756273 8.09 ENSMUST00000078049.12
ENSMUST00000236711.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr14_-_101846459 8.07 ENSMUST00000161991.8
TBC1 domain family, member 4
chr8_+_46338498 8.02 ENSMUST00000034053.7
PDZ and LIM domain 3
chr3_-_151953894 7.88 ENSMUST00000196529.5
nexilin
chr6_-_69792108 7.83 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr9_+_123902143 7.64 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr11_-_106641454 7.59 ENSMUST00000068021.9
platelet/endothelial cell adhesion molecule 1
chr8_+_46338557 7.46 ENSMUST00000210422.2
PDZ and LIM domain 3
chr14_+_79753055 7.17 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr1_-_66974492 7.11 ENSMUST00000120415.8
ENSMUST00000119429.8
myosin, light polypeptide 1
chr1_-_66974694 7.08 ENSMUST00000186202.7
myosin, light polypeptide 1
chr13_-_41513215 7.08 ENSMUST00000224803.2
neural precursor cell expressed, developmentally down-regulated gene 9
chr3_+_90520408 7.01 ENSMUST00000198128.2
S100 calcium binding protein A6 (calcyclin)
chr10_+_115653152 7.01 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr19_-_34231600 6.97 ENSMUST00000238147.2
actin, alpha 2, smooth muscle, aorta
chr18_-_14105670 6.75 ENSMUST00000025288.9
zinc finger protein 521
chr11_+_63023893 6.60 ENSMUST00000108700.2
peripheral myelin protein 22
chr1_+_180158035 6.57 ENSMUST00000070181.7
inositol 1,4,5-trisphosphate 3-kinase B
chr11_+_63023395 6.48 ENSMUST00000108701.8
peripheral myelin protein 22
chrX_+_72527208 6.44 ENSMUST00000033741.15
ENSMUST00000169489.2
biglycan
chrX_+_158410229 6.39 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr3_+_60436163 6.36 ENSMUST00000194201.6
ENSMUST00000193517.6
muscleblind like splicing factor 1
chr12_-_101785307 6.24 ENSMUST00000021603.9
fibulin 5
chr3_-_151971391 6.13 ENSMUST00000199470.5
ENSMUST00000200589.5
nexilin
chr6_+_38895902 6.08 ENSMUST00000003017.13
thromboxane A synthase 1, platelet
chr7_-_126224848 6.06 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr3_+_90520176 6.01 ENSMUST00000001051.9
S100 calcium binding protein A6 (calcyclin)
chr1_-_82746169 5.94 ENSMUST00000027331.3
transmembrane 4 L six family member 20
chr11_+_44508137 5.87 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
early B cell factor 1
chr10_+_33071964 5.79 ENSMUST00000219211.2
triadin
chr4_-_43523745 5.76 ENSMUST00000150592.2
tropomyosin 2, beta
chr4_-_44710408 5.70 ENSMUST00000134968.9
ENSMUST00000173821.8
ENSMUST00000174319.8
ENSMUST00000173733.8
ENSMUST00000172866.8
ENSMUST00000165417.9
ENSMUST00000107825.9
ENSMUST00000102932.10
ENSMUST00000107827.9
ENSMUST00000107826.9
ENSMUST00000014174.14
paired box 5
chr11_-_75918551 5.66 ENSMUST00000021207.7
refilin B
chr6_+_41515152 5.66 ENSMUST00000103291.2
ENSMUST00000192856.6
T cell receptor beta, constant region 1
chr3_+_94284812 5.60 ENSMUST00000200009.2
RAR-related orphan receptor gamma
chr5_+_17779273 5.53 ENSMUST00000030568.14
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_60436570 5.40 ENSMUST00000192607.6
muscleblind like splicing factor 1
chr3_+_94284739 5.34 ENSMUST00000197040.5
RAR-related orphan receptor gamma
chr12_-_114646685 5.34 ENSMUST00000194350.6
ENSMUST00000103504.3
immunoglobulin heavy variable V1-18
chr2_-_73360069 5.30 ENSMUST00000094681.11
WAS/WASL interacting protein family, member 1
chrX_+_106132055 5.28 ENSMUST00000150494.2
purinergic receptor P2Y, G-protein coupled 10
chr8_-_83128437 5.26 ENSMUST00000209573.3
interleukin 15
chr1_-_134883645 5.26 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr10_-_27492827 5.23 ENSMUST00000092639.12
laminin, alpha 2
chr1_-_169938060 5.15 ENSMUST00000027985.8
ENSMUST00000194690.6
discoidin domain receptor family, member 2
chr6_-_124865155 5.13 ENSMUST00000024044.7
CD4 antigen
chrX_+_158410528 5.00 ENSMUST00000073094.10
SH3-domain kinase binding protein 1
chr15_-_66673425 4.98 ENSMUST00000168589.8
src-like adaptor
chrX_-_47543029 4.93 ENSMUST00000114958.8
E74-like factor 4 (ets domain transcription factor)
chr1_+_107456731 4.91 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_41498716 4.84 ENSMUST00000070380.5
protease, serine 2
chr4_-_129452148 4.83 ENSMUST00000167288.8
ENSMUST00000134336.3
lymphocyte protein tyrosine kinase
chr4_-_129452180 4.81 ENSMUST00000067240.11
lymphocyte protein tyrosine kinase
chr6_+_67586695 4.76 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr7_-_30520563 4.71 ENSMUST00000186339.7
ENSMUST00000163504.8
ENSMUST00000186059.2
free fatty acid receptor 2
chr6_+_145879839 4.62 ENSMUST00000032383.14
sarcospan
chr10_-_62343516 4.60 ENSMUST00000020271.13
serglycin
chr9_+_123901979 4.51 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr11_+_95733489 4.51 ENSMUST00000100532.10
ENSMUST00000036088.11
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_-_83421333 4.49 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr7_+_100143250 4.47 ENSMUST00000153287.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_103133524 4.47 ENSMUST00000090475.10
ets homologous factor
chr2_-_103133503 4.46 ENSMUST00000111176.9
ets homologous factor
chr3_-_145355725 4.44 ENSMUST00000029846.5
cellular communication network factor 1
chr9_-_44437694 4.43 ENSMUST00000062215.8
chemokine (C-X-C motif) receptor 5
chr12_-_114672701 4.42 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr11_-_100151847 4.34 ENSMUST00000080893.7
keratin 17
chr1_-_66984178 4.32 ENSMUST00000027151.12
myosin, light polypeptide 1
chr5_-_103777145 4.32 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr17_+_35643818 4.31 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr8_-_3928495 4.29 ENSMUST00000209176.2
ENSMUST00000011445.8
CD209d antigen
chr6_+_21986445 4.24 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr14_-_101846551 4.24 ENSMUST00000100340.4
TBC1 domain family, member 4
chr13_+_83652352 4.24 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr17_+_35643853 4.19 ENSMUST00000113879.4
histocompatibility 2, Q region locus 6
chr8_+_107237483 4.18 ENSMUST00000080797.8
cadherin 3
chr12_-_114710326 4.18 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr6_+_29060215 4.13 ENSMUST00000069789.12
leptin
chr16_+_45430743 4.12 ENSMUST00000161347.9
ENSMUST00000023339.5
germinal center associated, signaling and motility
chrX_-_9335525 4.09 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr4_-_141553306 4.09 ENSMUST00000102481.4
chymotrypsin-like elastase family, member 2A
chr10_+_42736771 4.08 ENSMUST00000105494.8
Scm polycomb group protein like 4
chr4_-_84593226 4.00 ENSMUST00000175800.8
ENSMUST00000176418.8
ENSMUST00000175969.8
ENSMUST00000176370.2
ENSMUST00000176947.8
ENSMUST00000102820.9
ENSMUST00000107198.9
ENSMUST00000175756.8
ENSMUST00000176691.8
basonuclin 2
chr6_+_70495224 3.89 ENSMUST00000103396.2
immunoglobulin kappa variable 3-12
chr2_-_60793536 3.85 ENSMUST00000028347.13
RNA binding motif, single stranded interacting protein 1
chr7_+_100142977 3.84 ENSMUST00000129324.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_46496506 3.80 ENSMUST00000209984.2
lactate dehydrogenase A
chr10_+_42736345 3.79 ENSMUST00000063063.14
Scm polycomb group protein like 4
chr1_-_95595280 3.78 ENSMUST00000043336.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr11_-_101785181 3.75 ENSMUST00000057054.8
mesenchyme homeobox 1
chr7_+_30252687 3.74 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr14_-_59578768 3.73 ENSMUST00000166121.4
PHD finger protein 11B
chr7_+_75292971 3.72 ENSMUST00000207998.2
A kinase (PRKA) anchor protein 13
chr4_-_87951565 3.71 ENSMUST00000078090.12
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr15_+_61857390 3.71 ENSMUST00000159327.2
ENSMUST00000167731.8
myelocytomatosis oncogene
chr4_-_11386756 3.70 ENSMUST00000108313.8
ENSMUST00000108311.9
epithelial splicing regulatory protein 1
chr7_+_46496929 3.67 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr9_+_89081262 3.67 ENSMUST00000068569.5
B cell leukemia/lymphoma 2 related protein A1b
chr17_+_87270504 3.66 ENSMUST00000024956.15
ras homolog family member Q
chr19_-_57107330 3.65 ENSMUST00000111526.8
actin-binding LIM protein 1
chr6_+_65502344 3.60 ENSMUST00000212375.2
TNFAIP3 interacting protein 3
chr1_+_133965228 3.59 ENSMUST00000162779.2
fibromodulin
chr10_-_93146825 3.59 ENSMUST00000151153.2
ELK3, member of ETS oncogene family
chr3_+_95406567 3.58 ENSMUST00000015664.5
cathepsin K
chr11_+_44290884 3.57 ENSMUST00000170513.3
ENSMUST00000102796.10
interleukin 12b
chr11_-_79421397 3.56 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr13_-_100922910 3.55 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr13_-_117161921 3.54 ENSMUST00000223949.2
poly (ADP-ribose) polymerase family, member 8
chr1_+_60948149 3.49 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr11_-_70545424 3.35 ENSMUST00000108549.2
profilin 1
chr8_-_105350898 3.34 ENSMUST00000212882.2
ENSMUST00000163783.4
cadherin 16
chr19_+_58658779 3.32 ENSMUST00000057270.9
pancreatic lipase
chr11_-_70545450 3.32 ENSMUST00000018437.3
profilin 1
chrX_+_74425990 3.31 ENSMUST00000033541.5
FUN14 domain containing 2
chr11_-_48836975 3.31 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr1_-_169938298 3.31 ENSMUST00000192312.6
discoidin domain receptor family, member 2
chr11_+_67090878 3.30 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr13_-_117162041 3.29 ENSMUST00000022239.8
poly (ADP-ribose) polymerase family, member 8
chr3_+_145827410 3.28 ENSMUST00000039450.5
mucolipin 3
chr2_+_18681812 3.27 ENSMUST00000028071.13
Bmi1 polycomb ring finger oncogene
chr1_-_170755136 3.27 ENSMUST00000046322.14
ENSMUST00000159171.2
Fc receptor-like A
chr9_-_123691077 3.26 ENSMUST00000182350.3
chemokine (C motif) receptor 1
chr9_+_108183996 3.24 ENSMUST00000194701.6
ENSMUST00000193490.2
ras homolog family member A
chr14_+_22069709 3.24 ENSMUST00000075639.11
leucine rich melanocyte differentiation associated
chrX_+_163221035 3.20 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr7_-_104019046 3.17 ENSMUST00000106831.3
tripartite motif-containing 30B
chr4_-_11386679 3.14 ENSMUST00000043781.14
ENSMUST00000108310.8
epithelial splicing regulatory protein 1
chr15_-_56557920 3.09 ENSMUST00000050544.8
hyaluronan synthase 2
chr6_+_65502292 3.07 ENSMUST00000212402.2
TNFAIP3 interacting protein 3
chr14_+_120513076 3.06 ENSMUST00000088419.13
muscleblind like splicing factor 2
chr15_+_6609322 3.06 ENSMUST00000090461.12
FYN binding protein
chr10_-_18890281 3.05 ENSMUST00000146388.2
tumor necrosis factor, alpha-induced protein 3
chr11_-_78074377 3.00 ENSMUST00000102483.5
ribosomal protein L23A
chr3_+_87754057 3.00 ENSMUST00000107581.9
SH2 domain containing 2A
chr6_+_21985902 2.97 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr10_-_27492792 2.94 ENSMUST00000189575.2
laminin, alpha 2
chr11_-_100098333 2.93 ENSMUST00000007272.8
keratin 14
chr6_+_149210941 2.93 ENSMUST00000190785.7
ENSMUST00000189932.7
ENSMUST00000100765.11
retroelement silencing factor 1
chr11_+_95733109 2.93 ENSMUST00000107714.9
ENSMUST00000107711.8
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr3_+_87754310 2.92 ENSMUST00000029709.7
SH2 domain containing 2A
chr6_+_97187650 2.92 ENSMUST00000044681.7
ADP-ribosylation factor-like 6 interacting protein 5
chr17_+_37581103 2.92 ENSMUST00000038580.7
histocompatibility 2, M region locus 3
chr11_+_81936531 2.91 ENSMUST00000021011.3
chemokine (C-C motif) ligand 7
chr7_+_46496552 2.90 ENSMUST00000005051.6
lactate dehydrogenase A
chr1_-_69726384 2.90 ENSMUST00000187184.7
IKAROS family zinc finger 2
chr2_+_127750978 2.87 ENSMUST00000110344.2
acyl-Coenzyme A oxidase-like
chr7_-_104018989 2.86 ENSMUST00000164410.2
tripartite motif-containing 30B
chr2_-_181223787 2.86 ENSMUST00000057816.15
uridine-cytidine kinase 1-like 1
chr1_-_134883577 2.86 ENSMUST00000168381.8
protein phosphatase 1, regulatory subunit 12B
chr4_+_134591847 2.83 ENSMUST00000030627.8
Rh blood group, D antigen
chr3_+_89979948 2.82 ENSMUST00000121503.8
ENSMUST00000119570.8
tropomyosin 3, gamma
chr13_+_83652150 2.82 ENSMUST00000198199.5
myocyte enhancer factor 2C
chr8_+_95161006 2.78 ENSMUST00000211816.2
NLR family, CARD domain containing 5
chr9_+_69896748 2.76 ENSMUST00000034754.12
ENSMUST00000085393.13
ENSMUST00000117450.8
BCL2/adenovirus E1B interacting protein 2
chr8_-_105350533 2.75 ENSMUST00000212662.2
cadherin 16
chr3_-_135313982 2.74 ENSMUST00000132668.8
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr9_+_123635556 2.74 ENSMUST00000216072.2
chemokine (C-X-C motif) receptor 6
chr9_+_123635529 2.73 ENSMUST00000049810.9
chemokine (C-X-C motif) receptor 6
chrX_-_12539778 2.70 ENSMUST00000060108.7
RIKEN cDNA 1810030O07 gene
chr6_+_149210889 2.70 ENSMUST00000130664.8
ENSMUST00000046689.13
retroelement silencing factor 1
chr18_-_14105591 2.69 ENSMUST00000234025.2
zinc finger protein 521
chr1_+_82210833 2.68 ENSMUST00000023262.6
predicted gene 9747
chr5_+_67126304 2.67 ENSMUST00000132991.5
LIM and calponin homology domains 1
chr7_-_80475722 2.66 ENSMUST00000205304.2
IQ motif containing GTPase activating protein 1
chr8_-_105350881 2.65 ENSMUST00000211903.2
cadherin 16
chr12_-_114878652 2.64 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr7_+_30122685 2.64 ENSMUST00000046177.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr11_+_96177449 2.62 ENSMUST00000049352.8
homeobox B7
chr16_-_21980200 2.60 ENSMUST00000115379.2
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_47126719 2.59 ENSMUST00000140512.8
ENSMUST00000035822.2
calcium homeostasis modulator family member 2
chr15_-_98505508 2.57 ENSMUST00000096224.6
adenylate cyclase 6
chr5_+_138228074 2.57 ENSMUST00000159798.8
ENSMUST00000159964.2
neurexophilin and PC-esterase domain family, member 5
chr14_+_120513106 2.57 ENSMUST00000227012.2
ENSMUST00000167459.3
muscleblind like splicing factor 2
chr10_+_42736644 2.55 ENSMUST00000105495.8
Scm polycomb group protein like 4
chr3_-_101743539 2.52 ENSMUST00000061831.11
mab-21-like 3
chr7_+_27207226 2.52 ENSMUST00000125990.2
ENSMUST00000065487.7
periaxin
chr5_+_13449276 2.51 ENSMUST00000030714.9
ENSMUST00000141968.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_+_67021509 2.49 ENSMUST00000173689.8
jumonji domain containing 1C
chr1_-_131161312 2.45 ENSMUST00000212202.2
Ras association (RalGDS/AF-6) domain family member 5
chr10_-_93146937 2.44 ENSMUST00000008542.12
ELK3, member of ETS oncogene family
chr9_-_58065800 2.43 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr19_+_58658838 2.42 ENSMUST00000238108.2
pancreatic lipase
chr6_+_70584375 2.42 ENSMUST00000197560.2
immunoglobulin kappa variable 3-7
chr3_-_57483175 2.38 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr12_+_75355082 2.38 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr5_+_3393893 2.37 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chr7_+_88079465 2.36 ENSMUST00000107256.4
RAB38, member RAS oncogene family
chr7_+_27770655 2.29 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr15_+_101152078 2.29 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr1_-_170755109 2.29 ENSMUST00000162136.2
ENSMUST00000162887.2
Fc receptor-like A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
3.1 9.2 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
2.9 11.6 GO:1903921 renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
2.7 8.1 GO:0060854 patterning of lymph vessels(GO:0060854)
2.5 7.6 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
2.2 4.5 GO:0035697 CD8-positive, alpha-beta T cell extravasation(GO:0035697)
2.1 8.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.7 10.4 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
1.7 6.9 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.4 8.5 GO:0001866 NK T cell proliferation(GO:0001866)
1.4 4.2 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
1.4 4.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
1.4 8.1 GO:0001575 globoside metabolic process(GO:0001575)
1.3 15.9 GO:0048251 elastic fiber assembly(GO:0048251)
1.3 2.6 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
1.3 1.3 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
1.2 11.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.2 12.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.2 7.0 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.2 4.6 GO:0033380 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
1.1 3.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
1.1 6.6 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
1.1 3.3 GO:0009955 adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011)
1.0 10.4 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.0 3.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.0 12.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.0 3.1 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
1.0 3.0 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
1.0 6.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
1.0 10.9 GO:0072615 interleukin-17 secretion(GO:0072615)
1.0 2.9 GO:0002481 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.9 4.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.9 3.7 GO:0090095 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.9 11.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.9 2.7 GO:1904629 negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
0.9 5.5 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.9 8.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.9 3.6 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.9 7.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.8 10.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 3.2 GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.8 2.4 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.7 8.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.7 9.6 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.7 2.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.7 2.0 GO:0003032 detection of oxygen(GO:0003032)
0.7 2.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.7 2.0 GO:0006021 inositol biosynthetic process(GO:0006021)
0.7 2.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.6 14.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.6 3.8 GO:0061056 sclerotome development(GO:0061056)
0.6 3.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6 4.3 GO:0090383 phagosome acidification(GO:0090383)
0.6 4.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.6 2.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.6 2.3 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.5 8.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.5 6.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.5 4.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.5 1.5 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.5 16.4 GO:0045109 intermediate filament organization(GO:0045109)
0.5 1.9 GO:0042335 cuticle development(GO:0042335)
0.5 1.0 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.5 2.4 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.5 1.9 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 1.9 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 2.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 2.6 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.4 8.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.4 13.1 GO:0032060 bleb assembly(GO:0032060)
0.4 2.5 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.4 1.7 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.4 2.9 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.4 4.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 1.6 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.4 2.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 3.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.4 6.1 GO:2000194 regulation of female gonad development(GO:2000194)
0.4 15.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 6.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.3 4.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 6.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 5.7 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.3 2.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 1.2 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 2.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 3.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 1.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 2.8 GO:0032264 IMP salvage(GO:0032264)
0.3 1.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.8 GO:0097184 amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.3 0.8 GO:0048880 medulla oblongata development(GO:0021550) hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.3 5.7 GO:0021670 lateral ventricle development(GO:0021670)
0.3 1.0 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.3 13.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 4.8 GO:0031000 response to caffeine(GO:0031000)
0.2 1.7 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 0.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 1.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 2.7 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.2 2.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 1.3 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 1.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 8.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 2.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 6.2 GO:0048535 lymph node development(GO:0048535)
0.2 0.6 GO:1904735 negative regulation of electron carrier activity(GO:1904733) regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904735) negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904736)
0.2 7.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 7.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 0.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 1.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2 4.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 1.3 GO:1904587 response to glycoprotein(GO:1904587)
0.2 1.3 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 1.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of phospholipase A2 activity(GO:0032430)
0.2 6.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.2 23.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 7.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2 1.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.6 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 5.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.7 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 3.1 GO:0032506 cytokinetic process(GO:0032506)
0.1 1.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.6 GO:0043586 tongue development(GO:0043586)
0.1 1.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 2.2 GO:0008272 sulfate transport(GO:0008272)
0.1 3.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 1.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 1.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 2.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.9 GO:0006983 ER overload response(GO:0006983)
0.1 3.7 GO:0046039 GTP metabolic process(GO:0046039)
0.1 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 2.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 5.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 1.0 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) positive regulation of mononuclear cell migration(GO:0071677) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 3.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 4.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 3.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.5 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 1.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.9 GO:0003283 atrial septum development(GO:0003283)
0.1 1.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 1.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 5.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 13.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.6 GO:0006825 copper ion transport(GO:0006825)
0.1 3.3 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 1.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 3.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 1.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 12.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.8 GO:0043276 anoikis(GO:0043276)
0.1 1.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 3.5 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 3.1 GO:0045576 mast cell activation(GO:0045576)
0.0 3.7 GO:0048663 neuron fate commitment(GO:0048663)
0.0 1.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 1.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 2.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 6.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.9 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 1.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 3.1 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.5 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 2.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0002155 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.4 GO:0021591 ventricular system development(GO:0021591)
0.0 0.5 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 2.2 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.6 GO:0071953 elastic fiber(GO:0071953)
1.6 14.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.4 5.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.2 18.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.2 7.0 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.2 11.6 GO:0030478 actin cap(GO:0030478)
0.9 3.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.8 9.1 GO:0045098 type III intermediate filament(GO:0045098)
0.8 2.4 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.7 2.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.6 8.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 4.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 4.6 GO:0042629 mast cell granule(GO:0042629)
0.4 13.1 GO:0043218 compact myelin(GO:0043218)
0.4 10.8 GO:0000242 pericentriolar material(GO:0000242)
0.4 10.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 3.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.6 GO:0035841 new growing cell tip(GO:0035841)
0.3 1.6 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.3 4.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 1.5 GO:0031251 PAN complex(GO:0031251)
0.3 0.9 GO:0043614 multi-eIF complex(GO:0043614)
0.3 35.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 7.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 8.2 GO:0005605 basal lamina(GO:0005605)
0.3 4.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.7 GO:0005869 dynactin complex(GO:0005869)
0.2 0.7 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 5.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.9 GO:0042611 MHC protein complex(GO:0042611)
0.2 1.3 GO:0070826 paraferritin complex(GO:0070826)
0.2 2.2 GO:0061574 ASAP complex(GO:0061574)
0.2 2.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.8 GO:0042382 paraspeckles(GO:0042382)
0.2 21.8 GO:0016459 myosin complex(GO:0016459)
0.2 3.0 GO:0031932 TORC2 complex(GO:0031932)
0.2 2.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 12.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 37.2 GO:0030017 sarcomere(GO:0030017)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 15.3 GO:0005884 actin filament(GO:0005884)
0.1 10.7 GO:0032432 actin filament bundle(GO:0032432)
0.1 2.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 24.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.5 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 3.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 5.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0035976 AP1 complex(GO:0035976)
0.1 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.3 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0036038 MKS complex(GO:0036038)
0.1 2.8 GO:0045095 keratin filament(GO:0045095)
0.1 3.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 6.5 GO:0000922 spindle pole(GO:0000922)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 3.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 9.0 GO:0042383 sarcolemma(GO:0042383)
0.1 7.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 6.3 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 23.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 34.8 GO:0016604 nuclear body(GO:0016604)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 16.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 3.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 7.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.9 GO:0043209 myelin sheath(GO:0043209)
0.0 6.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 31.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
3.9 15.7 GO:0045159 myosin II binding(GO:0045159)
2.9 11.6 GO:0019862 IgA binding(GO:0019862)
2.3 9.2 GO:0048030 disaccharide binding(GO:0048030)
1.9 9.6 GO:0042610 CD8 receptor binding(GO:0042610)
1.8 10.9 GO:0008142 oxysterol binding(GO:0008142)
1.6 8.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.6 9.4 GO:0042289 MHC class II protein binding(GO:0042289)
1.6 4.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.5 6.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.5 4.5 GO:0031726 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
1.4 4.2 GO:0036461 BLOC-2 complex binding(GO:0036461)
1.4 8.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.2 11.2 GO:0004568 chitinase activity(GO:0004568)
1.2 10.9 GO:0004126 cytidine deaminase activity(GO:0004126)
1.0 3.0 GO:0005368 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
1.0 7.0 GO:0015616 DNA translocase activity(GO:0015616)
1.0 11.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.9 10.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.9 11.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.8 18.0 GO:0044548 S100 protein binding(GO:0044548)
0.8 3.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 8.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 2.9 GO:0019809 spermidine binding(GO:0019809)
0.7 6.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 2.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 47.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 2.0 GO:0016872 inositol-3-phosphate synthase activity(GO:0004512) intramolecular lyase activity(GO:0016872)
0.6 6.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 3.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.6 2.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 1.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.5 8.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 1.9 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.4 3.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 8.0 GO:0038191 neuropilin binding(GO:0038191)
0.4 2.9 GO:1990254 keratin filament binding(GO:1990254)
0.4 11.1 GO:0003680 AT DNA binding(GO:0003680)
0.4 2.9 GO:0004849 uridine kinase activity(GO:0004849)
0.4 8.1 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.4 1.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.4 3.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 6.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 1.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.4 2.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.4 3.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 1.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.3 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 4.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 0.9 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 2.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 5.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 0.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 1.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3 0.8 GO:0052600 diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.3 5.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 3.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.3 1.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.3 5.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 0.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 0.7 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 2.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 6.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 3.7 GO:0005522 profilin binding(GO:0005522)
0.2 5.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 23.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 5.2 GO:0031005 filamin binding(GO:0031005)
0.2 10.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 4.3 GO:0005537 mannose binding(GO:0005537)
0.2 3.9 GO:0017166 vinculin binding(GO:0017166)
0.2 2.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 1.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 1.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.2 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 3.7 GO:0051400 BH domain binding(GO:0051400)
0.1 2.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 5.3 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 10.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 3.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 18.6 GO:0005178 integrin binding(GO:0005178)
0.1 2.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 6.1 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.1 3.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 4.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 3.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 6.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 2.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.7 GO:0070888 E-box binding(GO:0070888)
0.1 3.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.1 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 6.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 31.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 7.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 14.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 3.1 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 11.9 GO:0003779 actin binding(GO:0003779)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 4.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0001848 complement binding(GO:0001848)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.5 8.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 16.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 14.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 11.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 15.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 12.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 14.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 8.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.4 PID CONE PATHWAY Visual signal transduction: Cones
0.2 5.1 PID ARF 3PATHWAY Arf1 pathway
0.2 7.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 11.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 9.2 PID RAS PATHWAY Regulation of Ras family activation
0.2 11.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 7.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 16.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 7.0 PID AURORA B PATHWAY Aurora B signaling
0.1 3.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 7.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 8.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 5.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 5.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 15.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 17.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 12.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.2 PID INSULIN PATHWAY Insulin Pathway
0.1 5.7 PID CMYB PATHWAY C-MYB transcription factor network
0.1 5.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 5.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 4.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 9.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 22.1 REACTOME DEFENSINS Genes involved in Defensins
1.0 9.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.7 46.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 23.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 6.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 5.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 10.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 11.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 4.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 7.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 13.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 5.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 5.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 17.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 7.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 4.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 7.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 5.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 7.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 3.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 6.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 6.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 6.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 5.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 2.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 8.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 8.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 7.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 5.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 7.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 7.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 3.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA