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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfatc3

Z-value: 1.55

Motif logo

Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031902.11 Nfatc3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc3mm39_v1_chr8_+_106785434_1067854720.161.7e-01Click!

Activity profile of Nfatc3 motif

Sorted Z-values of Nfatc3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_96917804 14.79 ENSMUST00000231039.2
solute carrier family 38, member 4
chr3_+_137923521 14.46 ENSMUST00000090171.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_82957104 12.78 ENSMUST00000048246.5
fibrinogen beta chain
chr14_+_40827317 11.71 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr14_+_40827108 11.33 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr1_+_172525613 10.10 ENSMUST00000038495.5
C-reactive protein, pentraxin-related
chr6_+_21986445 9.81 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr6_+_21985902 9.28 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr14_+_40826970 8.28 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr12_+_8027767 8.24 ENSMUST00000037520.14
apolipoprotein B
chr13_+_30520416 8.23 ENSMUST00000222503.2
ENSMUST00000222370.2
ENSMUST00000066412.8
ENSMUST00000223201.2
angiotensin II receptor, type 1a
chr10_+_21253190 8.03 ENSMUST00000042699.14
aldehyde dehydrogenase 8 family, member A1
chr15_+_10249646 7.84 ENSMUST00000134410.8
prolactin receptor
chr1_+_88139678 7.56 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr15_+_9335636 7.51 ENSMUST00000072403.7
UDP glycosyltransferases 3 family, polypeptide A2
chr10_+_4561974 7.49 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr3_+_96432479 7.34 ENSMUST00000049208.11
hemojuvelin BMP co-receptor
chr1_+_171052623 7.24 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr6_-_21851827 6.60 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
tetraspanin 12
chr15_+_10224052 6.32 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr4_-_43523745 6.32 ENSMUST00000150592.2
tropomyosin 2, beta
chr18_+_87774402 6.30 ENSMUST00000091776.7
predicted gene 5096
chr4_-_43523595 6.24 ENSMUST00000107914.10
tropomyosin 2, beta
chr9_-_48516447 5.98 ENSMUST00000034808.12
ENSMUST00000119426.2
nicotinamide N-methyltransferase
chr1_+_88015524 5.89 ENSMUST00000113139.2
UDP glucuronosyltransferase 1 family, polypeptide A8
chr10_+_87696339 5.85 ENSMUST00000121161.8
insulin-like growth factor 1
chr16_+_22710785 5.84 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr3_-_151953894 5.77 ENSMUST00000196529.5
nexilin
chr1_+_58152295 5.72 ENSMUST00000040999.14
ENSMUST00000162011.3
aldehyde oxidase 3
chr15_+_102898966 5.70 ENSMUST00000001703.8
homeobox C8
chr1_-_172722589 5.64 ENSMUST00000027824.7
serum amyloid P-component
chr18_+_11052458 5.52 ENSMUST00000047762.10
GATA binding protein 6
chr4_-_62005498 5.39 ENSMUST00000107488.4
ENSMUST00000107472.8
ENSMUST00000084531.11
major urinary protein 3
chr1_+_88022776 5.34 ENSMUST00000150634.8
ENSMUST00000058237.14
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr8_+_48275178 5.30 ENSMUST00000079639.3
claudin 24
chr12_+_8027640 5.02 ENSMUST00000171271.8
ENSMUST00000037811.13
apolipoprotein B
chr7_-_70010341 4.95 ENSMUST00000032768.15
nuclear receptor subfamily 2, group F, member 2
chr11_+_96173355 4.94 ENSMUST00000125410.2
homeobox B8
chr5_+_21748523 4.91 ENSMUST00000035651.6
leucine rich repeat containing 17
chr1_+_87998487 4.88 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_+_124470053 4.79 ENSMUST00000049124.10
complement component 1, r subcomponent-like
chr8_+_48277493 4.77 ENSMUST00000038693.8
claudin 22
chr4_-_129472328 4.76 ENSMUST00000052835.9
family with sequence similarity 167, member B
chr1_-_180021218 4.74 ENSMUST00000159914.8
coenzyme Q8A
chr2_-_64806106 4.66 ENSMUST00000156765.2
growth factor receptor bound protein 14
chr8_+_104828253 4.61 ENSMUST00000034339.10
cadherin 5
chr4_-_107164315 4.60 ENSMUST00000126291.2
ENSMUST00000106748.2
ENSMUST00000129138.2
deiodinase, iodothyronine, type I
chr7_-_99276310 4.58 ENSMUST00000178124.3
trophoblast glycoprotein-like
chr6_+_48818567 4.49 ENSMUST00000203639.3
transmembrane protein 176A
chr5_-_103777145 4.30 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr5_-_18040713 4.28 ENSMUST00000197890.5
CD36 molecule
chr15_+_76579885 4.24 ENSMUST00000231028.2
glutamic pyruvic transaminase, soluble
chr11_+_72326337 4.23 ENSMUST00000076443.10
gamma-glutamyltransferase 6
chr5_-_89605622 4.17 ENSMUST00000049209.13
vitamin D binding protein
chr19_-_7943365 4.14 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr1_-_162694076 4.10 ENSMUST00000046049.14
flavin containing monooxygenase 1
chr16_+_17149235 4.09 ENSMUST00000023450.15
ENSMUST00000231884.2
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr19_-_6947076 4.07 ENSMUST00000237074.2
phospholipase C, beta 3
chr17_-_71156639 4.06 ENSMUST00000134654.2
ENSMUST00000172229.8
ENSMUST00000127719.2
TGFB-induced factor homeobox 1
chr10_+_69048914 4.05 ENSMUST00000163497.8
ENSMUST00000164212.8
ENSMUST00000067908.14
Rho-related BTB domain containing 1
chr5_-_18040647 4.02 ENSMUST00000082367.13
CD36 molecule
chrX_+_138464065 3.93 ENSMUST00000113027.8
ring finger protein 128
chr6_+_48818410 3.91 ENSMUST00000101426.11
ENSMUST00000168406.4
transmembrane protein 176A
chr15_-_91075933 3.90 ENSMUST00000069511.8
ATP-binding cassette, sub-family D (ALD), member 2
chr11_+_49500090 3.88 ENSMUST00000020617.3
FMS-like tyrosine kinase 4
chr17_-_68311073 3.86 ENSMUST00000024840.12
Rho GTPase activating protein 28
chr4_-_148021159 3.84 ENSMUST00000105712.2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr6_-_48818006 3.82 ENSMUST00000203229.3
transmembrane protein 176B
chr11_+_85723377 3.79 ENSMUST00000000095.7
T-box 2
chr4_-_82423985 3.78 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr11_-_80030735 3.77 ENSMUST00000136996.2
transcription elongation factor, mitochondrial
chr13_+_16189041 3.76 ENSMUST00000164993.2
inhibin beta-A
chr6_-_48818044 3.76 ENSMUST00000101429.11
ENSMUST00000204073.3
transmembrane protein 176B
chr6_-_48817914 3.73 ENSMUST00000164733.4
transmembrane protein 176B
chr10_-_105410280 3.67 ENSMUST00000061506.9
transmembrane and tetratricopeptide repeat containing 2
chr16_+_35891991 3.67 ENSMUST00000164916.9
coiled-coil domain containing 58
chr5_-_67256578 3.62 ENSMUST00000012664.11
paired-like homeobox 2b
chr19_-_8382424 3.60 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr3_+_108000425 3.56 ENSMUST00000151326.8
guanine nucleotide binding protein, alpha transducing 2
chr18_-_35760260 3.53 ENSMUST00000025212.8
solute carrier family 23 (nucleobase transporters), member 1
chr6_-_48818430 3.53 ENSMUST00000205147.3
transmembrane protein 176B
chr12_-_101784727 3.48 ENSMUST00000222587.2
fibulin 5
chr15_+_10952418 3.48 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr15_-_99717956 3.47 ENSMUST00000109024.9
LIM domain and actin binding 1
chr14_+_19801333 3.45 ENSMUST00000022340.5
nidogen 2
chr7_-_89176294 3.41 ENSMUST00000207932.2
protease, serine 23
chr14_+_33807935 3.40 ENSMUST00000022519.15
annexin A8
chr11_+_98938137 3.39 ENSMUST00000140772.2
insulin-like growth factor binding protein 4
chr1_+_171265103 3.39 ENSMUST00000043839.5
F11 receptor
chr6_-_142647985 3.38 ENSMUST00000205202.3
ENSMUST00000073173.12
ENSMUST00000111771.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_+_91661074 3.37 ENSMUST00000205480.2
ENSMUST00000206545.2
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chrX_-_8059597 3.37 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr6_-_48422307 3.37 ENSMUST00000114563.8
ENSMUST00000114558.8
ENSMUST00000101443.10
zinc finger protein 467
chr5_+_16139909 3.35 ENSMUST00000196750.2
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr19_-_6947112 3.33 ENSMUST00000025912.10
phospholipase C, beta 3
chr6_-_48818302 3.33 ENSMUST00000203355.3
ENSMUST00000166247.8
transmembrane protein 176B
chr11_+_72326358 3.33 ENSMUST00000108499.2
gamma-glutamyltransferase 6
chr2_+_85876205 3.32 ENSMUST00000213496.2
olfactory receptor 1034
chr3_-_59038634 3.32 ENSMUST00000200358.2
ENSMUST00000197220.2
purinergic receptor P2Y, G-protein coupled, 14
chr6_-_142647944 3.30 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_180021039 3.29 ENSMUST00000160482.8
ENSMUST00000170472.8
coenzyme Q8A
chr3_-_57202546 3.26 ENSMUST00000196506.2
transmembrane 4 superfamily member 1
chr14_+_56062422 3.18 ENSMUST00000172271.9
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
chr6_+_91661034 3.17 ENSMUST00000032185.9
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr14_+_56062252 3.14 ENSMUST00000024179.6
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
chr3_+_121761471 3.11 ENSMUST00000196479.5
ENSMUST00000197155.5
Rho GTPase activating protein 29
chr16_-_21980200 3.10 ENSMUST00000115379.2
insulin-like growth factor 2 mRNA binding protein 2
chr11_+_63023893 3.04 ENSMUST00000108700.2
peripheral myelin protein 22
chr9_+_77543776 3.02 ENSMUST00000057781.8
kelch-like 31
chr9_+_65172455 3.01 ENSMUST00000048762.8
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr10_-_95251327 3.01 ENSMUST00000172070.8
ENSMUST00000150432.8
suppressor of cytokine signaling 2
chr4_-_84593226 3.01 ENSMUST00000175800.8
ENSMUST00000176418.8
ENSMUST00000175969.8
ENSMUST00000176370.2
ENSMUST00000176947.8
ENSMUST00000102820.9
ENSMUST00000107198.9
ENSMUST00000175756.8
ENSMUST00000176691.8
basonuclin 2
chr13_+_113346193 3.00 ENSMUST00000038144.9
endothelial cell-specific molecule 1
chr18_-_64794338 2.99 ENSMUST00000025482.10
ATPase, class I, type 8B, member 1
chr10_-_95251145 2.97 ENSMUST00000119917.2
suppressor of cytokine signaling 2
chr1_-_150341911 2.96 ENSMUST00000162367.8
ENSMUST00000161611.8
ENSMUST00000161320.8
ENSMUST00000159035.2
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr1_-_93373145 2.88 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr10_+_69048506 2.86 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr17_+_37269468 2.83 ENSMUST00000040177.7
RNA polymerase I subunit H, antisense
chr12_+_52550775 2.83 ENSMUST00000219443.2
Rho GTPase activating protein 5
chrX_-_47602395 2.73 ENSMUST00000114945.9
ENSMUST00000037349.8
apoptosis-inducing factor, mitochondrion-associated 1
chr9_+_51959415 2.73 ENSMUST00000000590.16
ENSMUST00000238858.2
radixin
chr14_-_30645711 2.72 ENSMUST00000006697.17
inter-alpha trypsin inhibitor, heavy chain 3
chr12_+_111409087 2.71 ENSMUST00000109792.8
tumor necrosis factor, alpha-induced protein 2
chr6_+_29060215 2.69 ENSMUST00000069789.12
leptin
chr3_-_59038031 2.66 ENSMUST00000091112.6
ENSMUST00000065220.13
purinergic receptor P2Y, G-protein coupled, 14
chr9_+_51959534 2.66 ENSMUST00000061352.11
radixin
chr3_-_145355725 2.63 ENSMUST00000029846.5
cellular communication network factor 1
chr2_+_155593030 2.61 ENSMUST00000029140.12
ENSMUST00000132608.2
protein C receptor, endothelial
chr4_-_82423944 2.60 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr7_+_127311881 2.58 ENSMUST00000047393.7
cardiotrophin 1
chr9_+_7445822 2.55 ENSMUST00000034497.8
matrix metallopeptidase 3
chr9_+_107456086 2.55 ENSMUST00000149638.8
ENSMUST00000139274.8
ENSMUST00000130053.8
ENSMUST00000122985.8
ENSMUST00000127380.8
ENSMUST00000139581.2
N(alpha)-acetyltransferase 80, NatH catalytic subunit
chr17_+_28988271 2.55 ENSMUST00000233984.2
ENSMUST00000233460.2
mitogen-activated protein kinase 13
chr6_+_115398996 2.54 ENSMUST00000000450.5
peroxisome proliferator activated receptor gamma
chr1_+_178014983 2.54 ENSMUST00000161075.8
ENSMUST00000027783.14
desumoylating isopeptidase 2
chr14_+_33807964 2.54 ENSMUST00000120077.2
annexin A8
chr17_+_24955647 2.52 ENSMUST00000101800.7
methionine sulfoxide reductase B1
chr18_-_35855383 2.52 ENSMUST00000133064.8
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr14_-_30645503 2.48 ENSMUST00000227995.2
inter-alpha trypsin inhibitor, heavy chain 3
chr17_+_24955613 2.45 ENSMUST00000115262.9
methionine sulfoxide reductase B1
chr17_+_37269513 2.45 ENSMUST00000173814.2
RNA polymerase I subunit H, antisense
chr12_-_16660960 2.45 ENSMUST00000239165.2
ENSMUST00000111067.10
lipin 1
chr11_-_109886569 2.44 ENSMUST00000106669.3
ATP-binding cassette, sub-family A (ABC1), member 8b
chr3_+_94284739 2.42 ENSMUST00000197040.5
RAR-related orphan receptor gamma
chr8_-_122379631 2.41 ENSMUST00000046386.5
zinc finger, CCHC domain containing 14
chr4_-_148021217 2.41 ENSMUST00000019199.14
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr8_-_94739469 2.41 ENSMUST00000053766.14
autocrine motility factor receptor
chr8_-_37200051 2.40 ENSMUST00000098826.10
deleted in liver cancer 1
chr11_-_47270201 2.40 ENSMUST00000077221.6
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr1_+_171041583 2.39 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr11_+_63023395 2.39 ENSMUST00000108701.8
peripheral myelin protein 22
chr8_-_41494890 2.38 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr17_+_28988354 2.37 ENSMUST00000233109.2
ENSMUST00000004986.14
mitogen-activated protein kinase 13
chr1_-_169938060 2.36 ENSMUST00000027985.8
ENSMUST00000194690.6
discoidin domain receptor family, member 2
chr4_-_84593512 2.36 ENSMUST00000176612.8
basonuclin 2
chr11_-_35871300 2.33 ENSMUST00000018993.7
WW, C2 and coiled-coil domain containing 1
chr11_-_109886601 2.30 ENSMUST00000020948.15
ATP-binding cassette, sub-family A (ABC1), member 8b
chr14_+_55797468 2.29 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr18_-_60866186 2.27 ENSMUST00000237885.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_-_69048928 2.27 ENSMUST00000170048.2
RIKEN cDNA A930033H14 gene
chr9_+_88209250 2.27 ENSMUST00000034992.8
5' nucleotidase, ecto
chr12_+_91367764 2.26 ENSMUST00000021346.14
ENSMUST00000021343.8
thyroid stimulating hormone receptor
chr17_-_48739874 2.26 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr6_+_108637816 2.20 ENSMUST00000163617.2
basic helix-loop-helix family, member e40
chr6_-_129449739 2.18 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr11_+_67131403 2.18 ENSMUST00000170942.2
myosin, heavy polypeptide 4, skeletal muscle
chr17_+_43671314 2.17 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr7_-_126062272 2.17 ENSMUST00000032974.13
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr3_-_59038539 2.15 ENSMUST00000198838.2
purinergic receptor P2Y, G-protein coupled, 14
chr17_-_45903494 2.14 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr3_-_86455575 2.13 ENSMUST00000077524.4
mab-21-like 2
chr3_-_20329823 2.11 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr18_-_38130581 2.10 ENSMUST00000042944.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_+_91222470 2.09 ENSMUST00000031324.6
epiregulin
chr3_+_94284812 2.07 ENSMUST00000200009.2
RAR-related orphan receptor gamma
chr15_-_58828321 2.06 ENSMUST00000228067.2
MTSS I-BAR domain containing 1
chr2_-_148285450 2.06 ENSMUST00000099269.4
CD93 antigen
chr8_+_45960804 2.05 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr19_-_42741148 2.05 ENSMUST00000236659.2
ENSMUST00000076505.4
pyridine nucleotide-disulphide oxidoreductase domain 2
chr3_+_92272486 2.04 ENSMUST00000050397.2
small proline-rich protein 2F
chr6_-_142648027 2.01 ENSMUST00000204870.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_66984178 2.01 ENSMUST00000027151.12
myosin, light polypeptide 1
chr16_+_35892437 2.00 ENSMUST00000163352.9
ENSMUST00000231468.2
coiled-coil domain containing 58
chr11_+_95557783 1.99 ENSMUST00000125172.8
ENSMUST00000036374.6
prohibitin
chr15_+_3300249 1.98 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr5_-_67256388 1.97 ENSMUST00000174251.2
paired-like homeobox 2b
chr15_-_77813123 1.96 ENSMUST00000109748.9
ENSMUST00000109747.9
ENSMUST00000100486.6
ENSMUST00000005487.12
thioredoxin 2
chrX_+_21581135 1.94 ENSMUST00000033414.8
solute carrier family 6 (neurotransmitter transporter), member 14
chr14_+_55797443 1.90 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr19_+_40600836 1.90 ENSMUST00000134063.8
ectonucleoside triphosphate diphosphohydrolase 1
chr11_+_75546671 1.85 ENSMUST00000108431.3
myosin IC
chr1_-_169938298 1.84 ENSMUST00000192312.6
discoidin domain receptor family, member 2
chr17_-_45903410 1.81 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_67090878 1.80 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr5_+_53747796 1.80 ENSMUST00000113865.5
recombination signal binding protein for immunoglobulin kappa J region
chr18_+_4994600 1.79 ENSMUST00000140448.8
supervillin
chr7_+_46496929 1.78 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr14_+_67470884 1.73 ENSMUST00000176161.8
early B cell factor 2
chr8_+_45960855 1.73 ENSMUST00000141039.8
sorbin and SH3 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:0009087 methionine catabolic process(GO:0009087)
3.6 14.5 GO:0006069 ethanol oxidation(GO:0006069)
3.2 12.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
2.7 8.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
2.5 7.6 GO:0018879 biphenyl metabolic process(GO:0018879)
2.4 14.2 GO:0038161 prolactin signaling pathway(GO:0038161)
2.2 6.5 GO:0001762 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
2.0 26.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.9 5.6 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.8 5.5 GO:0021934 hindbrain tangential cell migration(GO:0021934)
1.8 7.2 GO:0046340 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) diacylglycerol catabolic process(GO:0046340)
1.8 5.3 GO:0006711 estrogen catabolic process(GO:0006711)
1.7 8.3 GO:0070543 response to linoleic acid(GO:0070543)
1.6 6.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.6 6.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.6 4.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.3 13.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
1.3 6.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
1.3 10.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.3 6.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.2 7.5 GO:0060523 prostate epithelial cord elongation(GO:0060523)
1.2 5.0 GO:0030091 protein repair(GO:0030091)
1.2 4.9 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.2 10.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.2 3.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.1 5.7 GO:0009115 xanthine catabolic process(GO:0009115)
1.1 5.5 GO:0007493 endodermal cell fate determination(GO:0007493)
1.1 9.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.1 7.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.0 1.0 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
1.0 3.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.9 2.7 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.9 8.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 5.8 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.8 3.8 GO:0060279 positive regulation of ovulation(GO:0060279)
0.8 3.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.7 2.2 GO:0090076 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.7 5.4 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.6 2.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.6 3.8 GO:0060596 mammary placode formation(GO:0060596)
0.6 3.0 GO:1905068 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.6 2.3 GO:0061295 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.6 2.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.6 4.5 GO:0048539 bone marrow development(GO:0048539)
0.6 3.9 GO:0015862 uridine transport(GO:0015862)
0.6 1.7 GO:0060854 patterning of lymph vessels(GO:0060854)
0.5 7.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 4.7 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.5 4.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 1.5 GO:0010710 regulation of collagen catabolic process(GO:0010710) melanocyte proliferation(GO:0097325)
0.5 4.5 GO:0072615 interleukin-17 secretion(GO:0072615)
0.4 3.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.4 0.9 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.4 1.3 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.4 1.7 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.4 12.9 GO:0080184 response to phenylpropanoid(GO:0080184)
0.4 1.7 GO:0060591 chondroblast differentiation(GO:0060591)
0.4 2.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 1.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.4 2.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4 1.2 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.4 3.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 3.9 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.4 3.9 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.4 1.9 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.4 3.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.4 2.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.4 1.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.4 1.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.3 2.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 5.1 GO:0015747 urate transport(GO:0015747)
0.3 1.0 GO:0003032 detection of oxygen(GO:0003032)
0.3 3.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 8.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.3 1.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 3.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.3 2.3 GO:1904587 response to glycoprotein(GO:1904587)
0.3 3.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.9 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.3 2.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.3 0.9 GO:0035627 ceramide transport(GO:0035627)
0.3 4.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 11.4 GO:0003416 endochondral bone growth(GO:0003416)
0.3 3.5 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.3 5.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 3.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 1.6 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.3 2.6 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 2.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.2 2.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.9 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 2.7 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.2 0.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 9.3 GO:0010842 retina layer formation(GO:0010842)
0.2 2.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 12.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 3.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.2 6.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.2 4.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 5.8 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2 2.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.2 1.8 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 1.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 1.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 5.4 GO:0032060 bleb assembly(GO:0032060)
0.2 8.7 GO:0010107 potassium ion import(GO:0010107)
0.2 2.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 2.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.2 4.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.2 1.3 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.2 3.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.2 1.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 2.7 GO:0051601 exocyst localization(GO:0051601)
0.2 1.4 GO:0019532 oxalate transport(GO:0019532)
0.2 1.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.6 GO:1903921 renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.2 4.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.2 2.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.9 GO:0006116 NADH oxidation(GO:0006116)
0.1 5.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.7 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 1.7 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.7 GO:0006742 NADP catabolic process(GO:0006742)
0.1 0.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.1 0.5 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 2.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 2.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 3.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 1.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 3.0 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:1990428 miRNA transport(GO:1990428)
0.1 0.6 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 1.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.5 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 5.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.0 GO:0008272 sulfate transport(GO:0008272)
0.1 2.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.2 GO:0014823 response to activity(GO:0014823)
0.1 0.9 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:0035694 protein hexamerization(GO:0034214) mitochondrial protein catabolic process(GO:0035694)
0.1 1.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 2.0 GO:0031424 keratinization(GO:0031424)
0.1 1.0 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 2.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 1.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 3.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 0.9 GO:0039702 viral budding via host ESCRT complex(GO:0039702) regulation of mitotic spindle assembly(GO:1901673)
0.0 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 2.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 2.2 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 2.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.9 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 7.9 GO:0007596 blood coagulation(GO:0007596)
0.0 3.4 GO:0006970 response to osmotic stress(GO:0006970)
0.0 2.5 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.0 GO:0045116 protein neddylation(GO:0045116)
0.0 2.7 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 7.4 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.5 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.9 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 3.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 1.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 1.8 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 3.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.7 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 6.2 GO:0015711 organic anion transport(GO:0015711)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.0 GO:0035107 appendage morphogenesis(GO:0035107) limb morphogenesis(GO:0035108)
0.0 0.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0034359 mature chylomicron(GO:0034359)
1.4 12.8 GO:0005577 fibrinogen complex(GO:0005577)
1.3 3.8 GO:0043512 inhibin A complex(GO:0043512)
1.1 7.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.0 8.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.9 3.5 GO:0071953 elastic fiber(GO:0071953)
0.8 12.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.7 8.2 GO:0031983 vesicle lumen(GO:0031983)
0.6 5.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.5 7.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 2.4 GO:0045160 myosin I complex(GO:0045160)
0.5 7.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 1.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 3.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 5.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 0.9 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.3 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 0.9 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.3 2.2 GO:0031673 H zone(GO:0031673)
0.3 2.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 0.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 0.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 25.7 GO:0016363 nuclear matrix(GO:0016363)
0.2 0.9 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 4.0 GO:0032982 myosin filament(GO:0032982)
0.1 2.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.7 GO:0031415 NatA complex(GO:0031415)
0.1 3.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 4.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 3.5 GO:0045120 pronucleus(GO:0045120)
0.1 2.7 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 2.0 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 3.4 GO:0043218 compact myelin(GO:0043218)
0.1 8.3 GO:0032420 stereocilium(GO:0032420)
0.1 1.5 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 5.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 4.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 2.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 11.6 GO:0005901 caveola(GO:0005901)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.9 GO:0016459 myosin complex(GO:0016459)
0.0 3.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 7.8 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 2.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 17.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0042383 sarcolemma(GO:0042383)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 48.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 5.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
4.8 14.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.9 8.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
2.8 14.2 GO:0004925 prolactin receptor activity(GO:0004925)
2.7 8.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
2.5 7.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
2.2 17.8 GO:0001849 complement component C1q binding(GO:0001849)
2.2 6.5 GO:0005368 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
2.2 6.5 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.8 7.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.7 8.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.4 5.7 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
1.3 3.8 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
1.3 6.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.2 3.5 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.2 6.9 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.1 4.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.0 4.2 GO:1902271 D3 vitamins binding(GO:1902271)
1.0 13.3 GO:0035473 lipase binding(GO:0035473)
1.0 3.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
1.0 6.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.0 5.8 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.8 4.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.8 31.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.7 4.5 GO:0008142 oxysterol binding(GO:0008142)
0.7 2.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.6 2.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.6 7.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 1.7 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.6 8.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 3.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 2.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 9.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5 1.5 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.5 3.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 2.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.5 3.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 0.9 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.4 1.9 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.4 1.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.4 1.2 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.4 4.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 2.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 4.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 3.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 5.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 3.0 GO:1901612 cardiolipin binding(GO:1901612)
0.3 3.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 0.9 GO:0038064 collagen receptor activity(GO:0038064)
0.3 0.8 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.3 6.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.2 GO:0043426 MRF binding(GO:0043426)
0.3 18.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 1.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 2.5 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 4.9 GO:0001972 retinoic acid binding(GO:0001972)
0.2 6.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.9 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 6.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.9 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 9.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 4.9 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.2 1.7 GO:0036122 BMP binding(GO:0036122)
0.2 8.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.2 2.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 1.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 6.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 4.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 7.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.8 GO:0017166 vinculin binding(GO:0017166)
0.1 3.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 8.0 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.9 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 3.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 5.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 3.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 12.4 GO:0051087 chaperone binding(GO:0051087)
0.1 2.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 8.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 9.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 1.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 1.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 4.4 GO:0005550 pheromone binding(GO:0005550)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 4.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 5.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 3.2 GO:0005178 integrin binding(GO:0005178)
0.0 2.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 10.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 5.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 33.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.5 16.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 3.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 4.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 7.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 10.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 10.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.8 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 5.4 PID IGF1 PATHWAY IGF1 pathway
0.1 6.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 4.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 5.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 8.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 6.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 5.8 PID BMP PATHWAY BMP receptor signaling
0.1 4.7 PID INSULIN PATHWAY Insulin Pathway
0.1 3.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.2 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 3.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 15.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 3.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 6.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 3.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 18.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.4 15.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.3 10.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.9 31.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.8 12.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 20.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 7.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 3.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.5 9.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 12.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 3.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 8.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 13.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 14.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 7.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 4.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 4.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 12.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 4.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 6.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 8.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 6.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 9.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 3.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 3.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 4.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 4.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 15.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 5.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 4.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 3.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 6.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 2.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.0 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.1 3.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 5.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 3.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 5.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.9 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 2.3 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions