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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfe2_Bach1_Mafk

Z-value: 1.95

Motif logo

Transcription factors associated with Nfe2_Bach1_Mafk

Gene Symbol Gene ID Gene Info
ENSMUSG00000058794.13 Nfe2
ENSMUSG00000025612.6 Bach1
ENSMUSG00000018143.11 Mafk

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafkmm39_v1_chr5_+_139777263_139777271-0.473.8e-05Click!
Bach1mm39_v1_chr16_+_87495792_87495872-0.244.6e-02Click!
Nfe2mm39_v1_chr15_-_103159892_103160081-0.085.2e-01Click!

Activity profile of Nfe2_Bach1_Mafk motif

Sorted Z-values of Nfe2_Bach1_Mafk motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_108823435 26.30 ENSMUST00000051757.14
solute carrier family 26 (sulfate transporter), member 1
chr19_+_12610870 21.33 ENSMUST00000119960.2
glycine-N-acyltransferase
chr9_-_86577940 19.03 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr19_+_12610668 15.79 ENSMUST00000044976.12
glycine-N-acyltransferase
chr1_+_58069090 14.65 ENSMUST00000001027.7
aldehyde oxidase 1
chr6_+_129510331 14.61 ENSMUST00000204956.2
ENSMUST00000204639.2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr11_-_50101592 12.25 ENSMUST00000143379.2
ENSMUST00000015981.12
ENSMUST00000102774.11
sequestosome 1
chr5_+_31274064 12.06 ENSMUST00000202769.2
tripartite motif-containing 54
chr5_+_31274046 12.05 ENSMUST00000013771.15
tripartite motif-containing 54
chr15_-_82291372 11.85 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr7_+_139414057 11.63 ENSMUST00000026548.14
adhesion G protein-coupled receptor A1
chr16_+_90017634 10.90 ENSMUST00000023707.11
superoxide dismutase 1, soluble
chr6_+_129510117 10.44 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_+_127399776 10.07 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_-_126398343 9.80 ENSMUST00000032934.12
aldolase A, fructose-bisphosphate
chr11_-_30599510 9.72 ENSMUST00000074613.4
acylphosphatase 2, muscle type
chrX_+_163052367 9.26 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr7_+_127400016 9.13 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_+_127399789 9.01 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_+_66872699 8.01 ENSMUST00000159365.8
ENSMUST00000054661.8
ENSMUST00000225182.2
ENSMUST00000159068.2
adrenergic receptor, alpha 1a
chr3_-_116762476 7.95 ENSMUST00000119557.8
palmdelphin
chr17_-_24863907 7.59 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr18_-_3281089 7.55 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr17_-_24863956 7.54 ENSMUST00000019684.13
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_-_126398165 7.24 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr2_+_11710101 6.87 ENSMUST00000138349.8
ENSMUST00000135341.8
ENSMUST00000128156.9
interleukin 15 receptor, alpha chain
chr12_+_16860931 6.80 ENSMUST00000020908.9
E2F transcription factor 6
chr2_+_11710246 6.75 ENSMUST00000148748.8
interleukin 15 receptor, alpha chain
chr18_-_35087355 6.61 ENSMUST00000025217.11
heat shock protein 9
chr1_-_134163102 6.36 ENSMUST00000187631.2
ENSMUST00000038191.8
ENSMUST00000086465.6
adenosine A1 receptor
chr6_-_83633064 6.23 ENSMUST00000014686.3
C-type lectin domain family 4, member f
chr19_-_38113056 6.14 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr7_+_127399848 5.85 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_+_120421496 5.85 ENSMUST00000026119.8
glucagon receptor
chr19_-_6593049 5.81 ENSMUST00000113451.9
solute carrier family 22 (organic anion/cation transporter), member 12
chr1_+_165596961 5.76 ENSMUST00000040298.5
cellular repressor of E1A-stimulated genes 1
chr14_-_36857202 5.76 ENSMUST00000165649.4
ENSMUST00000224769.2
growth hormone inducible transmembrane protein
chr2_+_91087668 5.64 ENSMUST00000111349.9
ENSMUST00000131711.8
protein kinase C and casein kinase substrate in neurons 3
chr18_+_61178211 5.55 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr2_+_11710523 5.48 ENSMUST00000138856.2
ENSMUST00000078834.12
ENSMUST00000114834.10
ENSMUST00000114833.10
ENSMUST00000114831.9
interleukin 15 receptor, alpha chain
chr19_-_8816530 5.19 ENSMUST00000096259.6
guanine nucleotide binding protein (G protein), gamma 3
chr6_+_129374260 5.12 ENSMUST00000032262.14
C-type lectin domain family 1, member b
chr9_+_110782861 5.06 ENSMUST00000196834.2
leucine rich repeat containing 2
chr14_-_36857083 5.05 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr2_+_136555364 4.95 ENSMUST00000028727.11
ENSMUST00000110098.4
synaptosomal-associated protein 25
chr6_+_129374441 4.78 ENSMUST00000112081.9
ENSMUST00000112079.3
C-type lectin domain family 1, member b
chr10_-_25412010 4.75 ENSMUST00000179685.3
small leucine-rich protein 1
chr4_+_116542741 4.75 ENSMUST00000135573.8
ENSMUST00000151129.8
peroxiredoxin 1
chr4_+_116543045 4.74 ENSMUST00000129315.8
ENSMUST00000106470.8
peroxiredoxin 1
chr17_-_45884179 4.67 ENSMUST00000165127.8
ENSMUST00000166469.8
ENSMUST00000024739.14
heat shock protein 90 alpha (cytosolic), class B member 1
chr2_+_25318642 4.62 ENSMUST00000102919.4
ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_121745354 4.61 ENSMUST00000062474.5
cytochrome P450, family 8, subfamily b, polypeptide 1
chr9_-_43151179 4.60 ENSMUST00000034512.7
out at first homolog
chr18_-_3280999 4.59 ENSMUST00000049942.13
cAMP responsive element modulator
chr18_+_12776358 4.57 ENSMUST00000234966.2
ENSMUST00000025294.9
tetratricopeptide repeat domain 39C
chr16_-_18161746 4.51 ENSMUST00000231372.2
ENSMUST00000130752.2
ENSMUST00000231605.2
ENSMUST00000115628.10
transport and golgi organization 2
chr11_+_80319424 4.48 ENSMUST00000173938.8
ENSMUST00000017572.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_-_49077986 4.48 ENSMUST00000046522.13
butyrophilin-like 9
chr4_-_19922599 4.41 ENSMUST00000029900.6
ATPase, H+ transporting, lysosomal V0 subunit D2
chr16_+_20513658 4.39 ENSMUST00000056518.13
family with sequence similarity 131, member A
chrX_+_73468140 4.36 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chrX_+_162873183 4.34 ENSMUST00000015545.10
collectrin, amino acid transport regulator
chr8_+_120163857 4.31 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr14_+_28740162 4.19 ENSMUST00000055662.4
leucine-rich repeats and transmembrane domains 1
chr1_-_33946802 4.18 ENSMUST00000115161.8
ENSMUST00000129464.8
ENSMUST00000062289.11
BEN domain containing 6
chr16_-_36810810 4.14 ENSMUST00000075869.13
F-box protein 40
chr1_-_180027151 4.11 ENSMUST00000161743.3
coenzyme Q8A
chr19_+_8568618 3.98 ENSMUST00000170817.2
ENSMUST00000010251.11
solute carrier family 22 (organic anion transporter), member 8
chr13_-_23894828 3.93 ENSMUST00000091706.14
homeostatic iron regulator
chr12_-_16696958 3.92 ENSMUST00000238839.2
lipin 1
chr15_+_10224052 3.90 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr12_+_71021395 3.83 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr15_-_98575332 3.83 ENSMUST00000120997.2
ENSMUST00000109149.9
ENSMUST00000003451.11
Rho family GTPase 1
chr18_-_64622092 3.74 ENSMUST00000235766.3
ENSMUST00000025484.9
ENSMUST00000237502.2
ENSMUST00000236586.3
ferrochelatase
chr3_+_122039206 3.74 ENSMUST00000029769.14
glutamate-cysteine ligase, modifier subunit
chr11_-_120521382 3.68 ENSMUST00000106181.8
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr17_-_45883421 3.67 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chrX_-_102230225 3.66 ENSMUST00000121720.2
nucleosome assembly protein 1-like 2
chr11_-_120520954 3.65 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr11_-_49077864 3.63 ENSMUST00000153999.3
ENSMUST00000066531.13
butyrophilin-like 9
chr13_-_23894697 3.62 ENSMUST00000091707.13
ENSMUST00000006787.8
homeostatic iron regulator
chr17_-_56440817 3.47 ENSMUST00000167545.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr19_+_56276343 3.47 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr9_+_110948492 3.43 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr11_-_79394904 3.42 ENSMUST00000164465.3
oligodendrocyte myelin glycoprotein
chr19_-_4087907 3.40 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr19_+_8816663 3.36 ENSMUST00000160556.8
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_138118565 3.36 ENSMUST00000118091.8
microsomal glutathione S-transferase 1
chr19_-_4087940 3.25 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr11_-_48762170 3.25 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr5_-_112400375 3.18 ENSMUST00000112385.8
crystallin, beta A4
chr1_-_120001752 3.02 ENSMUST00000056089.8
transmembrane protein 37
chr3_+_122039274 3.02 ENSMUST00000178826.8
glutamate-cysteine ligase, modifier subunit
chr1_-_75240551 3.01 ENSMUST00000186178.7
ENSMUST00000189769.7
ENSMUST00000027404.12
protein tyrosine phosphatase, receptor type, N
chr14_-_34032311 2.99 ENSMUST00000111917.3
ENSMUST00000228704.2
shieldin complex subunit 2
chr11_+_103061905 2.95 ENSMUST00000042286.12
ENSMUST00000218163.2
formin-like 1
chr18_-_43610829 2.91 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr6_-_16898440 2.89 ENSMUST00000031533.11
transcription factor EC
chr18_-_60743169 2.89 ENSMUST00000115318.4
synaptopodin
chr16_+_20367327 2.86 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr19_+_56276375 2.86 ENSMUST00000166049.8
hyaluronic acid binding protein 2
chr11_+_78068931 2.84 ENSMUST00000147819.8
TLC domain containing 1
chr2_+_134627987 2.84 ENSMUST00000131552.5
ENSMUST00000110116.8
phospholipase C, beta 1
chr10_+_60113449 2.84 ENSMUST00000105465.8
ENSMUST00000179238.8
ENSMUST00000177779.8
ENSMUST00000004316.15
prosaposin
chr5_-_108022900 2.82 ENSMUST00000138111.8
ENSMUST00000112642.8
ecotropic viral integration site 5
chr12_+_89779237 2.79 ENSMUST00000110133.9
ENSMUST00000110130.4
neurexin III
chr2_+_67004178 2.79 ENSMUST00000239009.2
ENSMUST00000238912.2
xin actin-binding repeat containing 2
chr2_-_32271833 2.76 ENSMUST00000146423.2
RIKEN cDNA 1110008P14 gene
chr5_+_112403678 2.73 ENSMUST00000031286.13
ENSMUST00000131673.8
ENSMUST00000112375.2
crystallin, beta B1
chr2_-_160155536 2.71 ENSMUST00000109475.3
predicted gene 826
chr2_+_11710633 2.70 ENSMUST00000114832.3
interleukin 15 receptor, alpha chain
chr5_+_30971915 2.66 ENSMUST00000031058.15
microtubule-associated protein, RP/EB family, member 3
chr5_+_30972067 2.59 ENSMUST00000200692.4
microtubule-associated protein, RP/EB family, member 3
chrX_+_5959507 2.57 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr8_+_26022141 2.56 ENSMUST00000210846.2
ENSMUST00000167764.2
fibroblast growth factor receptor 1
chr7_-_30062197 2.55 ENSMUST00000046351.7
leucine rich repeat and fibronectin type III domain containing 3
chr6_+_51500881 2.51 ENSMUST00000049152.15
sorting nexin 10
chr2_-_84717036 2.48 ENSMUST00000054514.6
ENSMUST00000151799.8
reticulon 4 receptor-like 2
chr11_+_60619224 2.45 ENSMUST00000018743.5
mitochondrial elongation factor 2
chr12_+_89779178 2.44 ENSMUST00000238943.2
neurexin III
chr10_-_81262948 2.43 ENSMUST00000078185.14
ENSMUST00000020461.15
ENSMUST00000105321.10
nuclear factor I/C
chr18_-_63825380 2.36 ENSMUST00000025476.4
thioredoxin-like 1
chr17_-_24439712 2.31 ENSMUST00000024930.8
tubulin epsilon and delta complex 2
chr14_+_67953687 2.29 ENSMUST00000150768.8
potassium channel tetramerisation domain containing 9
chr13_-_113800172 2.23 ENSMUST00000054650.5
heat shock protein 3
chr11_+_87473027 2.22 ENSMUST00000133202.3
septin 4
chr3_-_89309944 2.21 ENSMUST00000057431.6
lens epithelial protein
chr19_-_4092218 2.13 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr9_-_107556823 2.11 ENSMUST00000010205.9
guanine nucleotide binding protein, alpha transducing 1
chr10_+_128626772 2.10 ENSMUST00000219404.2
ENSMUST00000026411.8
matrix metallopeptidase 19
chr1_-_75195127 2.08 ENSMUST00000079464.13
tubulin, alpha 4A
chr8_-_71308040 2.04 ENSMUST00000212509.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr11_-_116080361 2.03 ENSMUST00000148601.2
acyl-Coenzyme A oxidase 1, palmitoyl
chr1_-_79417732 2.03 ENSMUST00000185234.2
ENSMUST00000049972.6
secretogranin II
chr18_-_63825491 2.01 ENSMUST00000237004.2
thioredoxin-like 1
chr12_+_111504640 2.01 ENSMUST00000222375.2
ENSMUST00000222388.2
eukaryotic translation initiation factor 5
chr9_-_106353792 2.00 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chr9_+_65121944 1.96 ENSMUST00000069000.9
poly (ADP-ribose) polymerase family, member 16
chr17_+_25059079 1.95 ENSMUST00000164251.8
hydroxyacyl glutathione hydrolase
chr13_+_41040657 1.91 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_+_25452342 1.91 ENSMUST00000114950.2
polypeptide N-acetylgalactosaminyltransferase 11
chr8_+_105996469 1.90 ENSMUST00000172525.8
ENSMUST00000174837.8
ENSMUST00000173859.2
heat shock transcription factor 4
chr12_+_80565764 1.89 ENSMUST00000021558.8
polypeptide N-acetylgalactosaminyltransferase 16
chr18_+_24786748 1.89 ENSMUST00000068006.9
molybdenum cofactor sulfurase
chr7_+_26135039 1.89 ENSMUST00000119386.8
ENSMUST00000146907.3
NLR family, pyrin domain containing 4A
chr10_+_4561974 1.88 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr2_+_32518402 1.88 ENSMUST00000156578.8
adenylate kinase 1
chr2_-_38604503 1.86 ENSMUST00000028084.5
nuclear receptor subfamily 5, group A, member 1
chr11_+_120564185 1.84 ENSMUST00000135346.8
ENSMUST00000127269.8
ENSMUST00000131727.9
ENSMUST00000149389.8
ENSMUST00000153346.8
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr8_-_3767547 1.82 ENSMUST00000058040.7
C-type lectin domain family 4, member g
chr11_-_120524362 1.82 ENSMUST00000058162.14
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_+_7272514 1.80 ENSMUST00000015394.10
matrix metallopeptidase 13
chr7_+_126844359 1.80 ENSMUST00000205583.2
zinc finger protein 771
chr5_-_24963006 1.80 ENSMUST00000047119.5
crystallin, gamma N
chrX_-_121307036 1.79 ENSMUST00000079490.6
nucleosome assembly protein 1-like 3
chr2_+_163389068 1.78 ENSMUST00000109411.8
ENSMUST00000018094.13
hepatic nuclear factor 4, alpha
chr1_+_135945705 1.77 ENSMUST00000063719.15
transmembrane protein 9
chr14_+_67953584 1.76 ENSMUST00000145542.8
ENSMUST00000125212.2
potassium channel tetramerisation domain containing 9
chr9_-_106353571 1.76 ENSMUST00000123555.8
ENSMUST00000125850.2
poly (ADP-ribose) polymerase family, member 3
chr5_-_135601887 1.75 ENSMUST00000004936.10
ENSMUST00000201401.2
chemokine (C-C motif) ligand 24
chr15_+_3300249 1.75 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr6_-_115971914 1.74 ENSMUST00000015511.15
plexin D1
chr8_-_71308229 1.74 ENSMUST00000212086.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr2_+_71283620 1.73 ENSMUST00000037210.9
methionyl aminopeptidase type 1D (mitochondrial)
chr7_-_4909515 1.72 ENSMUST00000210663.2
predicted gene, 36210
chr10_-_109669053 1.72 ENSMUST00000238286.2
neuron navigator 3
chr11_+_78403019 1.70 ENSMUST00000001127.11
polymerase (DNA-directed), delta interacting protein 2
chr7_+_44117475 1.69 ENSMUST00000118493.8
Josephin domain containing 2
chrX_-_94240056 1.69 ENSMUST00000200628.2
ENSMUST00000197364.5
ENSMUST00000181987.8
CDC42 guanine nucleotide exchange factor (GEF) 9
chr2_+_156317416 1.69 ENSMUST00000029155.16
erythrocyte membrane protein band 4.1 like 1
chr7_+_126843446 1.66 ENSMUST00000052509.6
zinc finger protein 771
chr1_-_66984521 1.66 ENSMUST00000160100.2
myosin, light polypeptide 1
chr2_-_44817173 1.66 ENSMUST00000130991.8
glycosyltransferase-like domain containing 1
chr1_+_135945798 1.66 ENSMUST00000117950.2
transmembrane protein 9
chr9_-_110571645 1.64 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr14_+_4230569 1.64 ENSMUST00000090543.6
nuclear receptor subfamily 1, group D, member 2
chr12_-_101943134 1.63 ENSMUST00000221227.2
NADH:ubiquinone oxidoreductase subunit B1
chr14_-_55950939 1.62 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr4_+_130297132 1.61 ENSMUST00000105993.4
Na+/K+ transporting ATPase interacting 1
chr12_+_111725357 1.60 ENSMUST00000118471.8
ENSMUST00000122300.8
kinesin light chain 1
chr12_+_111132908 1.59 ENSMUST00000139162.8
ENSMUST00000060274.7
TNF receptor-associated factor 3
chr8_+_105996419 1.58 ENSMUST00000036127.9
ENSMUST00000163734.9
heat shock transcription factor 4
chr9_-_108888779 1.57 ENSMUST00000061973.5
three prime repair exonuclease 1
chr7_+_44117511 1.57 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr1_+_85992341 1.56 ENSMUST00000027432.9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr1_-_173195236 1.56 ENSMUST00000005470.5
ENSMUST00000111220.8
cell adhesion molecule 3
chr5_+_34683141 1.56 ENSMUST00000125817.8
ENSMUST00000067638.14
SH3-domain binding protein 2
chr4_-_94491473 1.53 ENSMUST00000107107.9
phospholipase A2, activating protein
chr1_-_66984178 1.52 ENSMUST00000027151.12
myosin, light polypeptide 1
chr7_+_110372860 1.50 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr13_-_58363431 1.50 ENSMUST00000076454.8
ENSMUST00000058735.12
ubiquilin 1
chr7_+_44117404 1.49 ENSMUST00000035844.11
Josephin domain containing 2
chr8_-_68427217 1.49 ENSMUST00000098696.10
ENSMUST00000038959.16
ENSMUST00000093469.11
pleckstrin and Sec7 domain containing 3
chr14_-_55950545 1.48 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr7_-_74958121 1.47 ENSMUST00000085164.7
synaptic vesicle glycoprotein 2 b
chr7_+_44117444 1.45 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr11_+_50101717 1.44 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr2_+_151947444 1.44 ENSMUST00000041500.8
sulfiredoxin 1 homolog (S. cerevisiae)
chrX_+_92718695 1.43 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr3_-_57202301 1.42 ENSMUST00000171384.8
transmembrane 4 superfamily member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 34.1 GO:0035754 B cell chemotaxis(GO:0035754)
2.9 14.6 GO:0009115 xanthine catabolic process(GO:0009115)
2.9 26.3 GO:0019532 oxalate transport(GO:0019532)
2.8 8.3 GO:0036363 transforming growth factor beta activation(GO:0036363)
2.7 8.0 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.5 7.5 GO:1904432 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
2.4 19.0 GO:1902031 regulation of NADP metabolic process(GO:1902031)
2.2 6.7 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
2.1 6.4 GO:0042323 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.9 5.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
1.7 6.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.7 5.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.6 25.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.3 5.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.2 6.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.0 17.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.0 10.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.9 2.8 GO:0060466 activation of meiosis involved in egg activation(GO:0060466) response to fluoride(GO:1902617) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.9 21.8 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.9 2.6 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.8 6.8 GO:0051409 response to nitrosative stress(GO:0051409)
0.8 3.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.8 3.2 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.8 10.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.8 2.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.7 3.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.7 5.8 GO:0033762 response to glucagon(GO:0033762)
0.7 4.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.7 3.4 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.7 4.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.7 2.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.7 3.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.6 1.8 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.6 1.8 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.6 1.8 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.6 2.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.6 4.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.6 0.6 GO:0035702 monocyte homeostasis(GO:0035702)
0.5 2.7 GO:0035617 stress granule disassembly(GO:0035617)
0.5 15.7 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.5 3.5 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.5 1.5 GO:0035973 aggrephagy(GO:0035973)
0.5 24.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.5 1.8 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.4 5.8 GO:0015747 urate transport(GO:0015747)
0.4 6.0 GO:0043248 proteasome assembly(GO:0043248)
0.4 1.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 2.6 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 6.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 2.1 GO:0050917 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.4 1.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 1.0 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 2.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 1.9 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 1.9 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.3 9.5 GO:0019430 removal of superoxide radicals(GO:0019430)
0.3 3.9 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 1.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.9 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.3 0.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 0.5 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 2.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 4.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 5.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 0.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 1.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 3.8 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 1.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.4 GO:0051031 tRNA transport(GO:0051031)
0.2 0.7 GO:0006069 ethanol oxidation(GO:0006069)
0.2 9.9 GO:0030220 platelet formation(GO:0030220)
0.2 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.8 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 1.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 2.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2 1.3 GO:0009992 cellular water homeostasis(GO:0009992)
0.2 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 5.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.6 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.2 9.3 GO:0030224 monocyte differentiation(GO:0030224)
0.2 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 4.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 3.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 12.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.2 5.2 GO:0007035 vacuolar acidification(GO:0007035)
0.2 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 4.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 29.7 GO:0009636 response to toxic substance(GO:0009636)
0.2 2.8 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.2 4.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 9.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.7 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 2.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 3.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 3.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 3.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.3 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1 3.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.7 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 1.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 4.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.7 GO:0051014 actin filament severing(GO:0051014)
0.1 1.4 GO:0014850 response to muscle activity(GO:0014850)
0.1 1.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 1.4 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.8 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 2.7 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.7 GO:0009405 pathogenesis(GO:0009405)
0.1 6.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 2.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 4.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.9 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 1.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.9 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 1.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 1.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.4 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 5.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 2.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 6.2 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.0 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 1.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 1.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.3 GO:0070814 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 1.9 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 2.4 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 2.8 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 17.1 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.0 0.3 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.2 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:2001179 regulation of interleukin-10 secretion(GO:2001179)
0.0 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.7 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.9 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0044753 amphisome(GO:0044753)
2.3 6.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.8 8.8 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
1.7 8.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.0 5.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.9 2.6 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.8 37.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.8 7.5 GO:1990357 terminal web(GO:1990357)
0.8 2.3 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.7 7.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 7.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.6 17.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 1.7 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.5 1.6 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.5 6.9 GO:0005838 proteasome regulatory particle(GO:0005838)
0.4 2.9 GO:0097444 spine apparatus(GO:0097444)
0.4 6.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 1.0 GO:0098855 HCN channel complex(GO:0098855)
0.3 9.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 2.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 1.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 6.4 GO:0032279 asymmetric synapse(GO:0032279)
0.3 4.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 4.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 1.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 0.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 0.8 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.2 3.2 GO:0044754 autolysosome(GO:0044754)
0.2 1.8 GO:0033010 paranodal junction(GO:0033010)
0.2 0.7 GO:1990589 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.2 2.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 8.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 11.5 GO:0032420 stereocilium(GO:0032420)
0.1 1.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 5.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 1.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 6.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 5.8 GO:0000502 proteasome complex(GO:0000502)
0.1 15.5 GO:0005875 microtubule associated complex(GO:0005875)
0.1 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 6.8 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 0.9 GO:0044233 mitochondrial outer membrane translocase complex(GO:0005742) ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.6 GO:0044299 C-fiber(GO:0044299)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 12.3 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 5.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.5 GO:0043679 axon terminus(GO:0043679)
0.0 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 20.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 22.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 13.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 59.2 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838) new growing cell tip(GO:0035841)
0.0 5.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 45.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.7 GO:0030016 myofibril(GO:0030016)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 18.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 9.3 GO:0016604 nuclear body(GO:0016604)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 37.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
8.5 34.1 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
6.3 19.0 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
3.1 9.3 GO:0008127 quercetin 2,3-dioxygenase activity(GO:0008127)
3.1 15.3 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
2.9 8.8 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
2.7 10.6 GO:0003998 acylphosphatase activity(GO:0003998)
2.3 6.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
2.0 6.1 GO:0034632 retinol transporter activity(GO:0034632)
2.0 8.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.9 5.8 GO:0004967 glucagon receptor activity(GO:0004967)
1.9 5.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.7 17.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.5 9.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.5 26.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.3 25.0 GO:0030957 Tat protein binding(GO:0030957)
1.2 3.7 GO:0030350 iron-responsive element binding(GO:0030350)
1.2 8.3 GO:0002135 CTP binding(GO:0002135)
1.0 4.0 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.8 3.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.8 6.2 GO:0005534 galactose binding(GO:0005534)
0.7 6.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.6 17.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.6 1.9 GO:0030151 molybdenum ion binding(GO:0030151)
0.6 1.9 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 9.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.6 2.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.6 1.8 GO:0070540 stearic acid binding(GO:0070540)
0.6 1.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.6 7.5 GO:0039706 co-receptor binding(GO:0039706)
0.5 4.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5 2.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.5 1.5 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.5 1.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 1.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.4 1.7 GO:0003883 CTP synthase activity(GO:0003883)
0.4 3.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 4.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 17.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.4 2.6 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.4 4.0 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.4 1.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 5.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 5.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 11.9 GO:0070330 aromatase activity(GO:0070330)
0.3 8.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 2.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.3 0.9 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.3 3.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 2.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 3.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 2.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.7 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2 2.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 6.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 4.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 6.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.6 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.2 3.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.8 GO:0008430 selenium binding(GO:0008430)
0.2 5.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 3.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 3.4 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 4.0 GO:0005521 lamin binding(GO:0005521)
0.1 3.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.4 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 5.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 3.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 4.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.4 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 2.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 5.7 GO:0043531 ADP binding(GO:0043531)
0.1 0.3 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 4.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0043559 insulin binding(GO:0043559)
0.1 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 3.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 7.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 4.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 21.8 GO:0008017 microtubule binding(GO:0008017)
0.1 1.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 2.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 2.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 5.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 9.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 2.1 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 5.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 7.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 2.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.4 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.6 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 3.2 GO:0008083 growth factor activity(GO:0008083)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 6.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 5.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.9 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0001047 core promoter binding(GO:0001047)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.5 GO:0048037 cofactor binding(GO:0048037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 15.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 1.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 22.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 11.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 8.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.6 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 5.1 PID AURORA B PATHWAY Aurora B signaling
0.1 6.1 PID AP1 PATHWAY AP-1 transcription factor network
0.1 8.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 6.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 2.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 11.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 11.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.9 PID E2F PATHWAY E2F transcription factor network
0.0 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 3.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 38.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 12.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.6 10.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.6 53.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.5 4.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.4 22.3 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.4 5.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 17.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 1.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 8.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 6.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 8.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 6.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 4.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 0.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 3.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 3.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 4.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 23.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 9.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 7.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 19.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 10.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 7.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.7 REACTOME KINESINS Genes involved in Kinesins
0.1 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 3.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 5.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 4.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.1 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling