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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfe2l2

Z-value: 0.98

Motif logo

Transcription factors associated with Nfe2l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000015839.7 Nfe2l2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfe2l2mm39_v1_chr2_-_75534985_755350230.142.3e-01Click!

Activity profile of Nfe2l2 motif

Sorted Z-values of Nfe2l2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_44984681 8.10 ENSMUST00000085351.7
histidine rich calcium binding protein
chr7_+_44984723 7.80 ENSMUST00000211327.2
histidine rich calcium binding protein
chr5_+_31274046 6.99 ENSMUST00000013771.15
tripartite motif-containing 54
chr2_-_164621641 6.92 ENSMUST00000103095.5
troponin C2, fast
chr10_+_17672004 6.52 ENSMUST00000037964.7
taxilin beta
chr1_-_172047282 6.39 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr12_-_76842263 6.13 ENSMUST00000082431.6
glutathione peroxidase 2
chr15_-_82291372 5.83 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr5_+_31274064 5.62 ENSMUST00000202769.2
tripartite motif-containing 54
chr18_-_64794338 5.45 ENSMUST00000025482.10
ATPase, class I, type 8B, member 1
chr13_-_42001075 4.80 ENSMUST00000179758.8
androgen dependent TFPI regulating protein
chr19_-_4092218 4.77 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr6_+_41928559 4.66 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr7_+_18817767 4.62 ENSMUST00000032568.14
ENSMUST00000122999.8
ENSMUST00000108473.10
ENSMUST00000108474.2
ENSMUST00000238982.2
dystrophia myotonica-protein kinase
chr14_+_28740162 4.61 ENSMUST00000055662.4
leucine-rich repeats and transmembrane domains 1
chr3_+_146302832 4.47 ENSMUST00000029837.14
ENSMUST00000147409.2
ENSMUST00000121133.2
urate oxidase
chr7_+_127399789 4.39 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr13_-_42001102 4.34 ENSMUST00000121404.8
androgen dependent TFPI regulating protein
chr19_-_4087940 4.19 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr16_-_18904240 4.18 ENSMUST00000103746.3
immunoglobulin lambda variable 1
chr1_-_120001752 4.09 ENSMUST00000056089.8
transmembrane protein 37
chr19_-_4927910 4.09 ENSMUST00000006626.5
actinin alpha 3
chr13_-_42000958 4.07 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr19_-_4087907 4.06 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr1_-_162641495 4.01 ENSMUST00000144916.8
ENSMUST00000140274.2
flavin containing monooxygenase 4
chr4_+_128999325 3.97 ENSMUST00000106064.10
ENSMUST00000030575.15
ENSMUST00000030577.11
transmembrane protein 54
chr4_-_138484889 3.83 ENSMUST00000030526.7
phospholipase A2, group IIF
chr9_-_106353792 3.82 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chr12_-_103925197 3.80 ENSMUST00000122229.8
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr7_+_127399776 3.70 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chrX_-_96420756 3.54 ENSMUST00000113832.2
ENSMUST00000037353.10
ectodysplasin A2 receptor
chr8_+_120163857 3.45 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr16_+_22738987 3.44 ENSMUST00000023587.12
fetuin beta
chr1_+_58069090 3.32 ENSMUST00000001027.7
aldehyde oxidase 1
chr9_-_106353571 3.29 ENSMUST00000123555.8
ENSMUST00000125850.2
poly (ADP-ribose) polymerase family, member 3
chr4_+_116543045 3.29 ENSMUST00000129315.8
ENSMUST00000106470.8
peroxiredoxin 1
chr3_-_116762617 3.29 ENSMUST00000143611.2
ENSMUST00000040097.14
palmdelphin
chr17_-_28569574 3.24 ENSMUST00000114799.8
ENSMUST00000219703.3
TEA domain family member 3
chr13_-_64460491 3.14 ENSMUST00000222570.2
ENSMUST00000220895.2
peroxiredoxin like 2C
chr18_+_4921663 3.06 ENSMUST00000143254.8
supervillin
chr7_+_127400016 2.93 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_+_11710101 2.91 ENSMUST00000138349.8
ENSMUST00000135341.8
ENSMUST00000128156.9
interleukin 15 receptor, alpha chain
chr13_-_64460382 2.86 ENSMUST00000021938.11
ENSMUST00000221118.2
ENSMUST00000221350.2
peroxiredoxin like 2C
chr16_+_22739191 2.83 ENSMUST00000116625.10
fetuin beta
chr4_+_116542741 2.80 ENSMUST00000135573.8
ENSMUST00000151129.8
peroxiredoxin 1
chr9_-_65330231 2.79 ENSMUST00000065894.7
solute carrier family 51, beta subunit
chr2_-_160155536 2.75 ENSMUST00000109475.3
predicted gene 826
chr19_-_32080496 2.73 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr7_-_126398165 2.71 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr7_+_127399848 2.62 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_-_116762476 2.61 ENSMUST00000119557.8
palmdelphin
chr7_-_30810422 2.58 ENSMUST00000039435.15
hepsin
chr19_-_4109446 2.55 ENSMUST00000189808.7
glutathione S-transferase pi 3
chr16_+_4825170 2.51 ENSMUST00000178155.9
small integral membrane protein 22
chr10_+_75404464 2.46 ENSMUST00000145928.8
ENSMUST00000131565.8
gamma-glutamyltransferase 1
chr10_+_75404482 2.42 ENSMUST00000134503.8
ENSMUST00000125770.8
ENSMUST00000128886.8
ENSMUST00000151212.8
gamma-glutamyltransferase 1
chr2_+_11710246 2.42 ENSMUST00000148748.8
interleukin 15 receptor, alpha chain
chr19_-_4889284 2.41 ENSMUST00000236451.2
ENSMUST00000236178.2
copper chaperone for superoxide dismutase
chr2_+_11710523 2.41 ENSMUST00000138856.2
ENSMUST00000078834.12
ENSMUST00000114834.10
ENSMUST00000114833.10
ENSMUST00000114831.9
interleukin 15 receptor, alpha chain
chr16_+_17379749 2.41 ENSMUST00000171002.10
ENSMUST00000023441.11
purinergic receptor P2X, ligand-gated ion channel, 6
chr15_-_76501525 2.31 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr16_+_4825146 2.31 ENSMUST00000184439.8
small integral membrane protein 22
chr14_-_21798678 2.29 ENSMUST00000075040.9
dual specificity phosphatase 13
chr9_-_106353303 2.27 ENSMUST00000156426.8
poly (ADP-ribose) polymerase family, member 3
chr19_-_4889314 2.24 ENSMUST00000235245.2
ENSMUST00000037246.7
copper chaperone for superoxide dismutase
chr14_+_4230569 2.22 ENSMUST00000090543.6
nuclear receptor subfamily 1, group D, member 2
chr11_-_69696428 2.19 ENSMUST00000051025.5
transmembrane protein 102
chr14_-_30637344 2.17 ENSMUST00000226547.2
inter-alpha trypsin inhibitor, heavy chain 3
chr9_-_121745354 2.15 ENSMUST00000062474.5
cytochrome P450, family 8, subfamily b, polypeptide 1
chr18_+_20380397 2.12 ENSMUST00000054128.7
desmoglein 1 gamma
chr6_+_17463925 2.12 ENSMUST00000115442.8
met proto-oncogene
chr12_-_113649535 2.12 ENSMUST00000103449.4
ENSMUST00000195707.3
immunoglobulin heavy variable 2-5
chr17_-_24863956 2.05 ENSMUST00000019684.13
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chrX_+_72719098 2.04 ENSMUST00000171398.2
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_+_45289391 2.03 ENSMUST00000148532.4
MEF2 activating motif and SAP domain containing transcriptional regulator
chr19_-_43928583 2.03 ENSMUST00000212396.2
dynamin binding protein
chr13_-_23894828 2.01 ENSMUST00000091706.14
homeostatic iron regulator
chr12_+_16860931 2.00 ENSMUST00000020908.9
E2F transcription factor 6
chr7_-_126398343 1.97 ENSMUST00000032934.12
aldolase A, fructose-bisphosphate
chr5_-_108823435 1.94 ENSMUST00000051757.14
solute carrier family 26 (sulfate transporter), member 1
chrX_+_163052367 1.93 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr5_-_147831610 1.93 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
solute carrier family 46, member 3
chr18_+_12637217 1.92 ENSMUST00000188815.2
laminin, alpha 3
chr9_+_121232480 1.89 ENSMUST00000210351.2
trafficking protein, kinesin binding 1
chr1_+_157353696 1.86 ENSMUST00000111700.8
SEC16 homolog B (S. cerevisiae)
chr12_-_113552322 1.80 ENSMUST00000103443.3
immunoglobulin heavy variable 2-2
chr14_+_4230658 1.78 ENSMUST00000225491.2
nuclear receptor subfamily 1, group D, member 2
chr6_-_68713748 1.77 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr18_-_35087355 1.72 ENSMUST00000025217.11
heat shock protein 9
chr2_+_25285878 1.72 ENSMUST00000028328.3
ectonucleoside triphosphate diphosphohydrolase 2
chr11_+_60428788 1.68 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr1_+_33947250 1.68 ENSMUST00000183034.5
dystonin
chr1_-_121260298 1.65 ENSMUST00000071064.13
insulin induced gene 2
chr1_-_121260274 1.64 ENSMUST00000161068.2
insulin induced gene 2
chrX_-_51702813 1.60 ENSMUST00000114857.2
glypican 3
chr12_-_17050332 1.56 ENSMUST00000134938.8
ENSMUST00000137960.2
PQ loop repeat containing
chr16_+_90017634 1.55 ENSMUST00000023707.11
superoxide dismutase 1, soluble
chr18_-_61344644 1.53 ENSMUST00000146409.8
solute carrier family 26 (sulfate transporter), member 2
chr9_+_108566513 1.53 ENSMUST00000192344.2
protein kinase, cAMP dependent regulatory, type II alpha
chr12_-_113617344 1.49 ENSMUST00000103447.2
immunoglobulin heavy variable V2-4
chr11_+_61575245 1.49 ENSMUST00000093019.6
family with sequence similarity 83, member G
chr4_-_57956411 1.48 ENSMUST00000030051.6
thioredoxin 1
chr15_+_54434576 1.48 ENSMUST00000025356.4
mal, T cell differentiation protein 2
chr15_-_75886166 1.44 ENSMUST00000060807.12
family with sequence similarity 83, member H
chr6_+_17306334 1.43 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chrX_-_51702790 1.43 ENSMUST00000069360.14
glypican 3
chr13_-_12476313 1.40 ENSMUST00000143693.8
ENSMUST00000144283.2
ENSMUST00000099820.10
ENSMUST00000135166.8
lectin, galactose binding, soluble 8
chr14_-_21798694 1.39 ENSMUST00000183943.2
dual specificity phosphatase 13
chr2_+_152360167 1.37 ENSMUST00000121912.2
defensin beta 28
chr9_-_44162762 1.35 ENSMUST00000034618.6
PDZ domain containing 3
chr4_+_117109148 1.35 ENSMUST00000062824.12
transmembrane protein 53
chr3_-_144514386 1.33 ENSMUST00000197013.2
chloride channel accessory 3A2
chr14_-_20529997 1.33 ENSMUST00000225132.2
annexin A7
chr6_+_48818567 1.32 ENSMUST00000203639.3
transmembrane protein 176A
chr11_+_120564185 1.32 ENSMUST00000135346.8
ENSMUST00000127269.8
ENSMUST00000131727.9
ENSMUST00000149389.8
ENSMUST00000153346.8
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr3_+_122039274 1.31 ENSMUST00000178826.8
glutamate-cysteine ligase, modifier subunit
chr17_-_24863907 1.29 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr1_+_165596961 1.24 ENSMUST00000040298.5
cellular repressor of E1A-stimulated genes 1
chr18_+_61178211 1.21 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr10_-_95158827 1.21 ENSMUST00000220279.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr14_+_67953687 1.20 ENSMUST00000150768.8
potassium channel tetramerisation domain containing 9
chr11_+_69523754 1.20 ENSMUST00000018909.4
fragile X mental retardation, autosomal homolog 2
chr11_-_50101592 1.19 ENSMUST00000143379.2
ENSMUST00000015981.12
ENSMUST00000102774.11
sequestosome 1
chr10_+_101517348 1.19 ENSMUST00000179929.8
ENSMUST00000219195.2
ENSMUST00000127504.9
MGAT4 family, member C
chrX_+_132809166 1.18 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr11_+_50101717 1.16 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr4_+_117109204 1.14 ENSMUST00000125943.8
ENSMUST00000106434.8
transmembrane protein 53
chr2_+_11710633 1.13 ENSMUST00000114832.3
interleukin 15 receptor, alpha chain
chr1_-_155022501 1.13 ENSMUST00000027744.10
major histocompatibility complex, class I-related
chr10_-_34294461 1.12 ENSMUST00000213269.2
ENSMUST00000099973.4
ENSMUST00000105512.8
ENSMUST00000047885.14
5'-nucleotidase domain containing 1
chr9_-_86577940 1.12 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr8_-_68574179 1.11 ENSMUST00000178529.2
pleckstrin and Sec7 domain containing 3
chr11_+_80319424 1.09 ENSMUST00000173938.8
ENSMUST00000017572.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_-_55950545 1.08 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr5_-_45607554 1.07 ENSMUST00000015950.12
quinoid dihydropteridine reductase
chr19_-_8906686 1.06 ENSMUST00000096242.5
rod outer segment membrane protein 1
chrX_+_132809189 1.06 ENSMUST00000113304.2
sushi-repeat-containing protein, X-linked 2
chr8_+_106052970 1.06 ENSMUST00000015000.12
ENSMUST00000098453.9
transmembrane protein 208
chr5_-_45607485 1.03 ENSMUST00000154962.8
ENSMUST00000118097.8
ENSMUST00000198258.5
quinoid dihydropteridine reductase
chr15_-_101801351 1.03 ENSMUST00000100179.2
keratin 76
chr9_+_5345450 1.02 ENSMUST00000151332.2
caspase 12
chr14_+_67953547 1.01 ENSMUST00000078053.13
potassium channel tetramerisation domain containing 9
chr5_-_73132045 1.00 ENSMUST00000043711.9
predicted gene 10135
chr7_-_97794679 1.00 ENSMUST00000098281.4
olfactory marker protein
chr2_-_163261439 0.99 ENSMUST00000046908.10
oxidative stress responsive serine rich 1
chr7_-_113875261 0.94 ENSMUST00000135570.8
proteasome subunit alpha 1
chr19_+_8906916 0.94 ENSMUST00000096241.6
echinoderm microtubule associated protein like 3
chr14_-_20443676 0.94 ENSMUST00000061444.5
mitochondrial ribosomal protein S16
chr9_+_107456086 0.93 ENSMUST00000149638.8
ENSMUST00000139274.8
ENSMUST00000130053.8
ENSMUST00000122985.8
ENSMUST00000127380.8
ENSMUST00000139581.2
N(alpha)-acetyltransferase 80, NatH catalytic subunit
chr18_-_63825380 0.93 ENSMUST00000025476.4
thioredoxin-like 1
chr3_+_108164242 0.92 ENSMUST00000090569.10
proteasome subunit alpha 5
chr12_-_83609217 0.91 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr11_+_100510043 0.91 ENSMUST00000107376.8
NFKB inhibitor interacting Ras-like protein 2
chr9_-_116004265 0.87 ENSMUST00000061101.12
transforming growth factor, beta receptor II
chr11_-_50216426 0.86 ENSMUST00000179865.8
ENSMUST00000020637.9
calnexin
chr18_-_43610829 0.86 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr9_+_65121944 0.85 ENSMUST00000069000.9
poly (ADP-ribose) polymerase family, member 16
chr9_+_5345405 0.84 ENSMUST00000027009.11
caspase 12
chr11_-_55075855 0.83 ENSMUST00000039305.6
solute carrier family 36 (proton/amino acid symporter), member 2
chr11_-_78277384 0.82 ENSMUST00000108294.2
forkhead box N1
chr16_+_20367327 0.82 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr2_+_151947444 0.81 ENSMUST00000041500.8
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_101875019 0.80 ENSMUST00000142873.8
post-GPI attachment to proteins 2
chr5_-_113216632 0.80 ENSMUST00000031295.8
crystallin, beta B2
chr9_-_21150100 0.78 ENSMUST00000164812.8
kelch-like ECH-associated protein 1
chr4_+_122910382 0.76 ENSMUST00000102649.4
tRNA isopentenyltransferase 1
chr10_+_127894816 0.75 ENSMUST00000052798.14
prostaglandin E synthase 3
chr12_-_113760187 0.75 ENSMUST00000192911.2
ENSMUST00000103455.3
immunoglobulin heavy variable 2-6-8
chr11_+_107370375 0.73 ENSMUST00000106750.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr12_+_71021395 0.73 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr2_+_153491363 0.72 ENSMUST00000072997.10
ENSMUST00000109773.8
ENSMUST00000109774.9
ENSMUST00000081628.13
ENSMUST00000103151.8
ENSMUST00000056495.14
ENSMUST00000088976.12
ENSMUST00000109772.8
ENSMUST00000103150.10
DNA methyltransferase 3B
chr10_+_127894843 0.70 ENSMUST00000084771.3
prostaglandin E synthase 3
chr14_-_55950939 0.70 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr9_-_116004386 0.70 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr7_-_80475722 0.69 ENSMUST00000205304.2
IQ motif containing GTPase activating protein 1
chr11_+_76836545 0.68 ENSMUST00000125145.8
bleomycin hydrolase
chr14_-_36857083 0.68 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr11_+_107370303 0.68 ENSMUST00000021063.13
ENSMUST00000106752.10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr9_+_38120348 0.65 ENSMUST00000093867.3
olfactory receptor 893
chr18_-_63825491 0.64 ENSMUST00000237004.2
thioredoxin-like 1
chr11_+_74255497 0.64 ENSMUST00000077794.4
olfactory receptor 412
chr7_-_113875342 0.64 ENSMUST00000033008.10
proteasome subunit alpha 1
chr7_+_141048722 0.64 ENSMUST00000058746.7
CD151 antigen
chr10_+_101517556 0.62 ENSMUST00000156751.8
MGAT4 family, member C
chr6_-_146403410 0.61 ENSMUST00000053273.15
inositol 1,4,5-triphosphate receptor 2
chr14_-_77274056 0.61 ENSMUST00000062789.15
laccase domain containing 1
chr19_+_29229147 0.61 ENSMUST00000025705.7
ENSMUST00000065796.10
ENSMUST00000236990.2
Janus kinase 2
chr5_-_45607463 0.61 ENSMUST00000197946.5
ENSMUST00000127562.3
quinoid dihydropteridine reductase
chr1_+_36730530 0.61 ENSMUST00000081180.7
ENSMUST00000193210.6
ENSMUST00000195151.6
cytochrome c oxidase subunit 5B
chr11_+_68779372 0.59 ENSMUST00000065213.5
ring finger protein 222
chr11_+_4207557 0.58 ENSMUST00000066283.12
leukemia inhibitory factor
chr7_-_103964662 0.57 ENSMUST00000106837.8
ENSMUST00000106839.9
ENSMUST00000070943.7
tripartite motif-containing 12A
chr14_+_54437843 0.57 ENSMUST00000103722.2
T cell receptor alpha joining 19
chr17_-_45884179 0.53 ENSMUST00000165127.8
ENSMUST00000166469.8
ENSMUST00000024739.14
heat shock protein 90 alpha (cytosolic), class B member 1
chr9_+_32305259 0.51 ENSMUST00000172015.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_+_163695571 0.51 ENSMUST00000044798.4
ENSMUST00000109396.2
potassium channel, subfamily K, member 15
chr1_-_130866978 0.50 ENSMUST00000016668.13
interleukin 19
chr17_-_71305003 0.50 ENSMUST00000024846.13
ENSMUST00000232766.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_-_10248979 0.50 ENSMUST00000029034.9
peripheral myelin protein 2
chr8_-_21392510 0.49 ENSMUST00000122025.9
predicted gene 15056

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.9 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
2.8 8.3 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
2.2 11.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.6 9.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.5 6.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.4 4.1 GO:0014728 regulation of the force of skeletal muscle contraction(GO:0014728) regulation of skeletal muscle contraction by chemo-mechanical energy conversion(GO:0014862)
1.2 13.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.9 2.6 GO:0034769 basement membrane disassembly(GO:0034769)
0.7 5.4 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.7 2.0 GO:0015881 creatine transport(GO:0015881)
0.7 2.0 GO:0002625 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.7 3.3 GO:0009115 xanthine catabolic process(GO:0009115)
0.6 4.9 GO:1901750 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 3.0 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.5 1.6 GO:0002663 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.5 4.0 GO:0042737 drug catabolic process(GO:0042737)
0.5 2.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.4 1.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4 1.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.4 1.9 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.4 4.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4 8.9 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.3 1.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 2.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 0.8 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3 2.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.3 3.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 1.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 4.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 12.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 0.8 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.2 0.7 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.2 1.4 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 7.6 GO:0019430 removal of superoxide radicals(GO:0019430)
0.2 1.4 GO:0009992 cellular water homeostasis(GO:0009992)
0.2 1.9 GO:0019532 oxalate transport(GO:0019532)
0.2 1.5 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 0.8 GO:0036233 proline transmembrane transport(GO:0035524) glycine import(GO:0036233)
0.2 0.8 GO:0043418 homocysteine catabolic process(GO:0043418)
0.2 3.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.2 0.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.2 4.5 GO:0046415 urate metabolic process(GO:0046415)
0.2 1.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 1.7 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2 1.7 GO:0051409 response to nitrosative stress(GO:0051409)
0.2 2.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 2.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 0.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 2.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 1.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 1.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.6 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.1 0.4 GO:1901856 negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.1 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 6.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 4.0 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 3.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 6.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 1.5 GO:0008272 sulfate transport(GO:0008272)
0.1 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.7 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 1.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.5 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 4.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 1.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 3.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 5.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.5 GO:0030950 zygotic determination of anterior/posterior axis, embryo(GO:0007354) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 4.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 2.4 GO:0033198 response to ATP(GO:0033198)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 2.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.0 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 6.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.0 GO:0048733 sebaceous gland development(GO:0048733)
0.0 2.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 4.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.9 GO:0030224 monocyte differentiation(GO:0030224)
0.0 1.4 GO:0043276 anoikis(GO:0043276)
0.0 4.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.1 GO:0032620 interleukin-17 production(GO:0032620)
0.0 1.4 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.3 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) negative regulation of mesoderm development(GO:2000381)
0.0 3.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 3.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.3 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 3.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 1.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 3.0 GO:0043434 response to peptide hormone(GO:0043434)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
2.1 6.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.6 20.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 1.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.5 1.9 GO:0005608 laminin-3 complex(GO:0005608)
0.4 3.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 1.2 GO:0044753 amphisome(GO:0044753)
0.4 6.9 GO:0005861 troponin complex(GO:0005861)
0.3 1.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 3.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 2.0 GO:1990357 terminal web(GO:1990357)
0.2 2.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 6.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 9.4 GO:0035861 site of double-strand break(GO:0035861)
0.2 2.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 4.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 0.9 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 2.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 4.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 8.2 GO:0032420 stereocilium(GO:0032420)
0.1 1.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.7 GO:0005605 basal lamina(GO:0005605)
0.1 0.9 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 2.5 GO:0045095 keratin filament(GO:0045095)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.1 1.8 GO:0030057 desmosome(GO:0030057)
0.1 6.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 8.4 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
3.4 13.6 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.0 6.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.9 9.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.9 2.7 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.7 2.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.7 3.3 GO:0004854 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdopterin cofactor binding(GO:0043546)
0.6 1.9 GO:0008127 quercetin 2,3-dioxygenase activity(GO:0008127)
0.6 1.7 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.5 5.4 GO:1901612 cardiolipin binding(GO:1901612)
0.5 2.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.5 1.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 4.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 4.5 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.4 4.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 6.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 1.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 1.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 1.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 2.7 GO:0017040 ceramidase activity(GO:0017040)
0.3 3.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 4.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 4.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 6.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 0.8 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.3 3.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 2.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 1.4 GO:1990254 keratin filament binding(GO:1990254)
0.2 6.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.4 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.2 3.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.7 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 5.8 GO:0070330 aromatase activity(GO:0070330)
0.2 1.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.0 GO:0039706 co-receptor binding(GO:0039706)
0.2 2.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 3.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.9 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.8 GO:0002135 CTP binding(GO:0002135)
0.1 0.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 3.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 3.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 3.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 8.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 6.5 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 13.0 GO:0044325 ion channel binding(GO:0044325)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 6.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 4.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 9.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 4.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0016209 antioxidant activity(GO:0016209)
0.0 1.9 GO:0019838 growth factor binding(GO:0019838)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 6.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 4.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 5.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.0 PID E2F PATHWAY E2F transcription factor network
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 14.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 0.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 3.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 6.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 3.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 6.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 5.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 3.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides