ISMARA results: Nfic

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfic_Nfib

Z-value: 2.07

Motif logo

Transcription factors associated with Nfic_Nfib

Gene Symbol	Gene ID	Gene Info
Nfic Ensembl NCBI MGI UniProt	ENSMUSG00000055053.19	Nfic
Nfib Ensembl NCBI MGI UniProt	ENSMUSG00000008575.18	Nfib

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nfib	mm39_v1_chr4_-_82423944_82423978	0.75	3.8e-14	Click!
Nfic	mm39_v1_chr10_-_81243475_81243515	0.41	3.2e-04	Click!

Activity profile of Nfic_Nfib motif

Sorted Z-values of Nfic_Nfib motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfic_Nfib

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr1_-_87501548 Show fit	20.64	ENSMUST00000068681.12	Ngef Ensembl NCBI MGI UniProt Show fit	neuronal guanine nucleotide exchange factor
chr8_+_95498822 Show fit	18.67	ENSMUST00000211956.2 ENSMUST00000211947.2	Cx3cl1 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X3-C motif) ligand 1
chr15_+_54609011 Show fit	18.53	ENSMUST00000050027.9	Ccn3 Ensembl NCBI MGI UniProt Show fit	cellular communication network factor 3
chr2_-_103114105 Show fit	17.36	ENSMUST00000111174.8	Ehf Ensembl NCBI MGI UniProt Show fit	ets homologous factor
chr11_+_78215026 Show fit	16.19	ENSMUST00000102478.4	Aldoc Ensembl NCBI MGI UniProt Show fit	aldolase C, fructose-bisphosphate
chrX_-_134968985 Show fit	12.73	ENSMUST00000049130.8	Bex2 Ensembl NCBI MGI UniProt Show fit	brain expressed X-linked 2
chr18_+_35252470 Show fit	12.49	ENSMUST00000237154.2	Ctnna1 Ensembl NCBI MGI UniProt Show fit	catenin (cadherin associated protein), alpha 1
chr1_-_75254989 Show fit	12.42	ENSMUST00000039534.11	Resp18 Ensembl NCBI MGI UniProt Show fit	regulated endocrine-specific protein 18
chr19_+_24651362 Show fit	12.07	ENSMUST00000057243.6	Tmem252 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 252
chr6_+_135339929 Show fit	11.80	ENSMUST00000032330.16	Emp1 Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 1
chr8_+_23247760 Show fit	11.63	ENSMUST00000033941.7	Plat Ensembl NCBI MGI UniProt Show fit	plasminogen activator, tissue
chr11_+_61376257 Show fit	11.51	ENSMUST00000064783.10 ENSMUST00000040522.7	Mfap4 Ensembl NCBI MGI UniProt Show fit	microfibrillar-associated protein 4
chr11_+_3939924 Show fit	11.48	ENSMUST00000109981.2	Gal3st1 Ensembl NCBI MGI UniProt Show fit	galactose-3-O-sulfotransferase 1
chr2_+_25179903 Show fit	11.46	ENSMUST00000028337.7	Lrrc26 Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing 26
chr18_+_82572595 Show fit	11.31	ENSMUST00000152071.9 ENSMUST00000142850.9 ENSMUST00000080658.12 ENSMUST00000133193.9 ENSMUST00000123251.9 ENSMUST00000153478.9 ENSMUST00000075372.13 ENSMUST00000102812.12 ENSMUST00000062446.15 ENSMUST00000114674.11 ENSMUST00000132369.3	Mbp Ensembl NCBI MGI UniProt Show fit	myelin basic protein
chr4_+_40920047 Show fit	11.07	ENSMUST00000030122.5	Spink4 Ensembl NCBI MGI UniProt Show fit	serine peptidase inhibitor, Kazal type 4
chr14_-_55354392 Show fit	10.29	ENSMUST00000022819.13	Jph4 Ensembl NCBI MGI UniProt Show fit	junctophilin 4
chr10_-_127024641 Show fit	10.15	ENSMUST00000218654.2	Arhgef25 Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 25
chr6_+_17306334 Show fit	9.88	ENSMUST00000007799.13 ENSMUST00000115456.6	Cav1 Ensembl NCBI MGI UniProt Show fit	caveolin 1, caveolae protein
chr12_+_36042899 Show fit	9.45	ENSMUST00000020898.12	Agr2 Ensembl NCBI MGI UniProt Show fit	anterior gradient 2
chr5_+_9316097 Show fit	9.22	ENSMUST00000134991.8 ENSMUST00000069538.14 ENSMUST00000115348.9	Elapor2 Ensembl NCBI MGI UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr18_+_37939442 Show fit	9.20	ENSMUST00000076807.7	Pcdhgc3 Ensembl NCBI MGI UniProt Show fit	protocadherin gamma subfamily C, 3
chr3_-_57202546 Show fit	8.97	ENSMUST00000196506.2	Tm4sf1 Ensembl NCBI MGI UniProt Show fit	transmembrane 4 superfamily member 1
chr8_-_95602952 Show fit	8.82	ENSMUST00000046461.9	Dok4 Ensembl NCBI MGI UniProt Show fit	docking protein 4
chr6_+_17306379 Show fit	8.76	ENSMUST00000115455.3	Cav1 Ensembl NCBI MGI UniProt Show fit	caveolin 1, caveolae protein
chr18_-_36648850 Show fit	8.63	ENSMUST00000025363.7	Hbegf Ensembl NCBI MGI UniProt Show fit	heparin-binding EGF-like growth factor
chr3_-_57202301 Show fit	8.19	ENSMUST00000171384.8	Tm4sf1 Ensembl NCBI MGI UniProt Show fit	transmembrane 4 superfamily member 1
chr7_+_40547608 Show fit	8.18	ENSMUST00000044705.12	Vstm2b Ensembl NCBI MGI UniProt Show fit	V-set and transmembrane domain containing 2B
chr6_+_135339543 Show fit	8.08	ENSMUST00000205156.3	Emp1 Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 1
chr9_+_22012357 Show fit	8.07	ENSMUST00000216872.2	Cnn1 Ensembl NCBI MGI UniProt Show fit	calponin 1
chr2_-_25359752 Show fit	8.04	ENSMUST00000114259.3 ENSMUST00000015234.13	Ptgds Ensembl NCBI MGI UniProt Show fit	prostaglandin D2 synthase (brain)
chr17_+_28491085 Show fit	7.87	ENSMUST00000169040.3	Ppard Ensembl NCBI MGI UniProt Show fit	peroxisome proliferator activator receptor delta
chr9_+_50663171 Show fit	7.86	ENSMUST00000214609.2	Cryab Ensembl NCBI MGI UniProt Show fit	crystallin, alpha B
chr7_-_25516041 Show fit	7.52	ENSMUST00000043314.10	Cyp2s1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily s, polypeptide 1
chr12_+_95658987 Show fit	7.48	ENSMUST00000057324.4	Flrt2 Ensembl NCBI MGI UniProt Show fit	fibronectin leucine rich transmembrane protein 2
chr3_+_94840352 Show fit	7.48	ENSMUST00000090839.12	Selenbp1 Ensembl NCBI MGI UniProt Show fit	selenium binding protein 1
chr8_-_65146079 Show fit	7.31	ENSMUST00000048967.9	Cpe Ensembl NCBI MGI UniProt Show fit	carboxypeptidase E
chr10_+_40505985 Show fit	7.28	ENSMUST00000019977.8 ENSMUST00000214102.2 ENSMUST00000213503.2 ENSMUST00000213442.2 ENSMUST00000216830.2	Ddo Ensembl NCBI MGI UniProt Show fit	D-aspartate oxidase
chr2_+_149672760 Show fit	7.18	ENSMUST00000109934.2 ENSMUST00000140870.8	Syndig1 Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1
chr17_+_35188888 Show fit	7.18	ENSMUST00000173680.2	Gm20481 Ensembl NCBI MGI UniProt Show fit	predicted gene 20481
chr4_+_137408975 Show fit	7.17	ENSMUST00000047243.12	Rap1gap Ensembl NCBI MGI UniProt Show fit	Rap1 GTPase-activating protein
chr7_+_111825063 Show fit	7.05	ENSMUST00000050149.12	Mical2 Ensembl NCBI MGI UniProt Show fit	microtubule associated monooxygenase, calponin and LIM domain containing 2
chr16_+_34605282 Show fit	7.01	ENSMUST00000023538.9	Mylk Ensembl NCBI MGI UniProt Show fit	myosin, light polypeptide kinase
chr18_-_64688271 Show fit	6.90	ENSMUST00000235459.2	Atp8b1 Ensembl NCBI MGI UniProt Show fit	ATPase, class I, type 8B, member 1
chr4_-_119515978 Show fit	6.84	ENSMUST00000106309.9 ENSMUST00000044426.8	Guca2b Ensembl NCBI MGI UniProt Show fit	guanylate cyclase activator 2b (retina)
chr6_+_21986445 Show fit	6.80	ENSMUST00000115382.8	Cped1 Ensembl NCBI MGI UniProt Show fit	cadherin-like and PC-esterase domain containing 1
chr17_-_27947863 Show fit	6.78	ENSMUST00000167489.2 ENSMUST00000138970.3 ENSMUST00000025054.10 ENSMUST00000114870.9	Spdef Ensembl NCBI MGI UniProt Show fit	SAM pointed domain containing ets transcription factor
chr17_+_43671314 Show fit	6.75	ENSMUST00000226087.2	Adgrf5 Ensembl NCBI MGI UniProt Show fit	adhesion G protein-coupled receptor F5
chr17_+_37253802 Show fit	6.67	ENSMUST00000040498.12	Rnf39 Ensembl NCBI MGI UniProt Show fit	ring finger protein 39
chr15_-_75963446 Show fit	6.65	ENSMUST00000228366.3	Nrbp2 Ensembl NCBI MGI UniProt Show fit	nuclear receptor binding protein 2
chr6_+_17306414 Show fit	6.54	ENSMUST00000150901.2	Cav1 Ensembl NCBI MGI UniProt Show fit	caveolin 1, caveolae protein
chr5_+_35971767 Show fit	6.50	ENSMUST00000114203.8 ENSMUST00000150146.2	Ablim2 Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 2
chr6_+_29433247 Show fit	6.48	ENSMUST00000101617.9 ENSMUST00000065090.8	Flnc Ensembl NCBI MGI UniProt Show fit	filamin C, gamma
chr9_+_44045859 Show fit	6.46	ENSMUST00000034650.15 ENSMUST00000098852.3 ENSMUST00000216002.2	Mcam Ensembl NCBI MGI UniProt Show fit	melanoma cell adhesion molecule
chr4_-_155103837 Show fit	6.37	ENSMUST00000126098.2 ENSMUST00000176194.8	Plch2 Ensembl NCBI MGI UniProt Show fit	phospholipase C, eta 2
chrX_+_149829131 Show fit	6.34	ENSMUST00000112685.8	Fgd1 Ensembl NCBI MGI UniProt Show fit	FYVE, RhoGEF and PH domain containing 1
chr2_+_156317416 Show fit	6.23	ENSMUST00000029155.16	Epb41l1 Ensembl NCBI MGI UniProt Show fit	erythrocyte membrane protein band 4.1 like 1
chr14_+_103750814 Show fit	6.22	ENSMUST00000095576.5	Scel Ensembl NCBI MGI UniProt Show fit	sciellin
chr15_-_73114855 Show fit	6.19	ENSMUST00000227686.2	Ptk2 Ensembl NCBI MGI UniProt Show fit	PTK2 protein tyrosine kinase 2
chr14_+_70768257 Show fit	6.16	ENSMUST00000047331.8	Lgi3 Ensembl NCBI MGI UniProt Show fit	leucine-rich repeat LGI family, member 3
chr9_-_60557076 Show fit	6.07	ENSMUST00000053171.14	Lrrc49 Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing 49
chr2_-_164246526 Show fit	6.02	ENSMUST00000109359.8 ENSMUST00000109358.8 ENSMUST00000103103.10	Matn4 Ensembl NCBI MGI UniProt Show fit	matrilin 4
chr15_+_102011352 Show fit	6.01	ENSMUST00000169627.9	Tns2 Ensembl NCBI MGI UniProt Show fit	tensin 2
chr5_-_135107078 Show fit	5.90	ENSMUST00000067935.11 ENSMUST00000076203.3	Vps37d Ensembl NCBI MGI UniProt Show fit	vacuolar protein sorting 37D
chr2_-_25360043 Show fit	5.87	ENSMUST00000114251.8	Ptgds Ensembl NCBI MGI UniProt Show fit	prostaglandin D2 synthase (brain)
chr6_-_115229128 Show fit	5.87	ENSMUST00000032462.9	Timp4 Ensembl NCBI MGI UniProt Show fit	tissue inhibitor of metalloproteinase 4
chr15_+_102011415 Show fit	5.83	ENSMUST00000046144.10	Tns2 Ensembl NCBI MGI UniProt Show fit	tensin 2
chr14_+_103750763 Show fit	5.76	ENSMUST00000227322.2	Scel Ensembl NCBI MGI UniProt Show fit	sciellin
chr11_+_78213791 Show fit	5.74	ENSMUST00000017534.15	Aldoc Ensembl NCBI MGI UniProt Show fit	aldolase C, fructose-bisphosphate
chr2_+_149672708 Show fit	5.61	ENSMUST00000109935.8	Syndig1 Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1
chr14_+_70768289 Show fit	5.45	ENSMUST00000226548.2	Lgi3 Ensembl NCBI MGI UniProt Show fit	leucine-rich repeat LGI family, member 3
chr6_-_115228800 Show fit	5.40	ENSMUST00000205131.2	Timp4 Ensembl NCBI MGI UniProt Show fit	tissue inhibitor of metalloproteinase 4
chrX_+_165021919 Show fit	5.40	ENSMUST00000060210.14 ENSMUST00000112233.8	Gpm6b Ensembl NCBI MGI UniProt Show fit	glycoprotein m6b
chr11_+_66847446 Show fit	5.27	ENSMUST00000211300.2 ENSMUST00000150220.2	Tmem238l Ensembl NCBI MGI UniProt Show fit	transmembrane protein 238 like
chr3_-_72964276 Show fit	5.19	ENSMUST00000192477.2	Slitrk3 Ensembl NCBI MGI UniProt Show fit	SLIT and NTRK-like family, member 3
chr3_-_85653573 Show fit	5.18	ENSMUST00000118408.8	Fam160a1 Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 160, member A1
chr3_+_62245765 Show fit	5.17	ENSMUST00000079300.13	Arhgef26 Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 26
chr9_-_107483855 Show fit	5.16	ENSMUST00000073448.12 ENSMUST00000194606.2 ENSMUST00000195662.6	Sema3b Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr5_+_35971697 Show fit	5.11	ENSMUST00000130233.8	Ablim2 Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 2
chr9_+_50662625 Show fit	5.05	ENSMUST00000217475.2	Cryab Ensembl NCBI MGI UniProt Show fit	crystallin, alpha B
chr2_-_26012751 Show fit	4.98	ENSMUST00000140993.2 ENSMUST00000028300.6	Nacc2 Ensembl NCBI MGI UniProt Show fit	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr11_+_96822213 Show fit	4.97	ENSMUST00000107633.2	Prr15l Ensembl NCBI MGI UniProt Show fit	proline rich 15-like
chr9_-_56068282 Show fit	4.87	ENSMUST00000034876.10	Tspan3 Ensembl NCBI MGI UniProt Show fit	tetraspanin 3
chr3_-_107129038 Show fit	4.87	ENSMUST00000029504.9	Cym Ensembl NCBI MGI UniProt Show fit	chymosin
chr9_-_99592116 Show fit	4.84	ENSMUST00000035048.12	Cldn18 Ensembl NCBI MGI UniProt Show fit	claudin 18
chr5_-_77262968 Show fit	4.73	ENSMUST00000081964.7	Hopx Ensembl NCBI MGI UniProt Show fit	HOP homeobox
chr1_+_133173826 Show fit	4.70	ENSMUST00000105082.9 ENSMUST00000038295.15	Plekha6 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family A member 6
chr15_+_81686622 Show fit	4.68	ENSMUST00000109553.10	Tef Ensembl NCBI MGI UniProt Show fit	thyrotroph embryonic factor
chr9_-_99592058 Show fit	4.66	ENSMUST00000136429.8	Cldn18 Ensembl NCBI MGI UniProt Show fit	claudin 18
chr5_-_139798992 Show fit	4.60	ENSMUST00000110832.8	Tmem184a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 184a
chr12_+_108376884 Show fit	4.58	ENSMUST00000109857.8	Eml1 Ensembl NCBI MGI UniProt Show fit	echinoderm microtubule associated protein like 1
chr3_-_63758672 Show fit	4.56	ENSMUST00000162269.9 ENSMUST00000159676.9 ENSMUST00000175947.8	Plch1 Ensembl NCBI MGI UniProt Show fit	phospholipase C, eta 1
chr2_-_118593087 Show fit	4.53	ENSMUST00000059997.9	Ccdc9b Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 9B
chr11_+_3438274 Show fit	4.53	ENSMUST00000064265.13	Pla2g3 Ensembl NCBI MGI UniProt Show fit	phospholipase A2, group III
chr12_+_108376801 Show fit	4.52	ENSMUST00000054955.14	Eml1 Ensembl NCBI MGI UniProt Show fit	echinoderm microtubule associated protein like 1
chr19_+_4644365 Show fit	4.51	ENSMUST00000113825.4	Pcx Ensembl NCBI MGI UniProt Show fit	pyruvate carboxylase
chr15_+_34306812 Show fit	4.50	ENSMUST00000226766.2 ENSMUST00000163455.9 ENSMUST00000022947.7 ENSMUST00000228570.2 ENSMUST00000227759.2	Matn2 Ensembl NCBI MGI UniProt Show fit	matrilin 2
chr3_+_90434160 Show fit	4.49	ENSMUST00000199538.5 ENSMUST00000164481.7 ENSMUST00000167598.6	S100a14 Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A14
chr7_+_34885782 Show fit	4.46	ENSMUST00000135452.8 ENSMUST00000001854.12	Slc7a10 Ensembl NCBI MGI UniProt Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr16_-_30369378 Show fit	4.45	ENSMUST00000140402.8	Tmem44 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 44
chr3_-_63872079 Show fit	4.44	ENSMUST00000161659.8	Slc33a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 33 (acetyl-CoA transporter), member 1
chr2_+_149672814 Show fit	4.41	ENSMUST00000137280.2 ENSMUST00000149705.2	Syndig1 Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1
chr2_+_165345707 Show fit	4.39	ENSMUST00000029196.5	Slc2a10 Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 10
chrX_+_165021897 Show fit	4.34	ENSMUST00000112235.8	Gpm6b Ensembl NCBI MGI UniProt Show fit	glycoprotein m6b
chr5_+_130398261 Show fit	4.30	ENSMUST00000086029.10	Caln1 Ensembl NCBI MGI UniProt Show fit	calneuron 1
chr19_-_61129211 Show fit	4.29	ENSMUST00000143264.8 ENSMUST00000205854.2	Zfp950 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 950
chr4_+_120018403 Show fit	4.29	ENSMUST00000030384.5	Edn2 Ensembl NCBI MGI UniProt Show fit	endothelin 2
chrX_-_51702790 Show fit	4.27	ENSMUST00000069360.14	Gpc3 Ensembl NCBI MGI UniProt Show fit	glypican 3
chr1_+_165130192 Show fit	4.24	ENSMUST00000111450.3	Gpr161 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 161
chr11_-_97040858 Show fit	4.23	ENSMUST00000118375.8	Tbkbp1 Ensembl NCBI MGI UniProt Show fit	TBK1 binding protein 1
chr12_+_74044435 Show fit	4.22	ENSMUST00000221220.2	Syt16 Ensembl NCBI MGI UniProt Show fit	synaptotagmin XVI
chr13_-_98951627 Show fit	4.21	ENSMUST00000224992.2 ENSMUST00000225840.2	Fcho2 Ensembl NCBI MGI UniProt Show fit	FCH domain only 2
chr11_-_58504307 Show fit	4.19	ENSMUST00000048801.8	Lypd8l Ensembl NCBI MGI UniProt Show fit	LY6/PLAUR domain containing 8 like
chr11_-_76359222 Show fit	4.16	ENSMUST00000065028.14	Abr Ensembl NCBI MGI UniProt Show fit	active BCR-related gene
chr4_+_43506966 Show fit	4.13	ENSMUST00000030183.10	Car9 Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 9
chr19_-_11796085 Show fit	4.09	ENSMUST00000211047.2 ENSMUST00000075304.14 ENSMUST00000211641.2	Stx3 Ensembl NCBI MGI UniProt Show fit	syntaxin 3
chr2_-_179867605 Show fit	4.09	ENSMUST00000015791.6	Lama5 Ensembl NCBI MGI UniProt Show fit	laminin, alpha 5
chr4_+_129941633 Show fit	4.07	ENSMUST00000044565.15 ENSMUST00000132251.2	Col16a1 Ensembl NCBI MGI UniProt Show fit	collagen, type XVI, alpha 1
chrX_+_135171002 Show fit	3.98	ENSMUST00000178632.8 ENSMUST00000053540.11	Bex3 Ensembl NCBI MGI UniProt Show fit	brain expressed X-linked 3
chr5_-_35828857 Show fit	3.94	ENSMUST00000129459.2 ENSMUST00000137935.2	Htra3 Ensembl NCBI MGI UniProt Show fit	HtrA serine peptidase 3
chr1_-_162687254 Show fit	3.93	ENSMUST00000131058.8	Fmo1 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 1
chr4_-_155095441 Show fit	3.92	ENSMUST00000105631.9 ENSMUST00000139976.9 ENSMUST00000145662.9	Plch2 Ensembl NCBI MGI UniProt Show fit	phospholipase C, eta 2
chr1_-_72914036 Show fit	3.91	ENSMUST00000027377.9	Igfbp5 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor binding protein 5
chr10_-_81127057 Show fit	3.89	ENSMUST00000045744.7	Tjp3 Ensembl NCBI MGI UniProt Show fit	tight junction protein 3
chr11_-_86964881 Show fit	3.88	ENSMUST00000020804.8	Gdpd1 Ensembl NCBI MGI UniProt Show fit	glycerophosphodiester phosphodiesterase domain containing 1
chr19_-_61129199 Show fit	3.87	ENSMUST00000180544.3	Zfp950 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 950
chr13_-_3968157 Show fit	3.85	ENSMUST00000223258.2 ENSMUST00000091853.12	Net1 Ensembl NCBI MGI UniProt Show fit	neuroepithelial cell transforming gene 1
chr1_-_190915441 Show fit	3.82	ENSMUST00000027941.14	Atf3 Ensembl NCBI MGI UniProt Show fit	activating transcription factor 3
chr3_-_89152320 Show fit	3.79	ENSMUST00000107464.8 ENSMUST00000090924.13	Trim46 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 46
chr8_-_106223502 Show fit	3.79	ENSMUST00000212303.2	Zdhhc1 Ensembl NCBI MGI UniProt Show fit	zinc finger, DHHC domain containing 1
chr17_-_31383976 Show fit	3.78	ENSMUST00000235870.2	Tff1 Ensembl NCBI MGI UniProt Show fit	trefoil factor 1
chrX_+_136552469 Show fit	3.77	ENSMUST00000075471.4	Il1rapl2 Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor accessory protein-like 2
chr1_-_162305573 Show fit	3.75	ENSMUST00000086074.12 ENSMUST00000070330.14	Dnm3 Ensembl NCBI MGI UniProt Show fit	dynamin 3
chr4_-_129121676 Show fit	3.75	ENSMUST00000106051.8	C77080 Ensembl NCBI MGI UniProt Show fit	expressed sequence C77080
chr16_+_58228806 Show fit	3.75	ENSMUST00000046663.8	Dcbld2 Ensembl NCBI MGI UniProt Show fit	discoidin, CUB and LCCL domain containing 2
chr3_+_94600863 Show fit	3.73	ENSMUST00000090848.10 ENSMUST00000173981.8 ENSMUST00000173849.8 ENSMUST00000174223.2	Selenbp2 Ensembl NCBI MGI UniProt Show fit	selenium binding protein 2
chr5_+_150119860 Show fit	3.72	ENSMUST00000202600.4	Fry Ensembl NCBI MGI UniProt Show fit	FRY microtubule binding protein
chr7_-_118594365 Show fit	3.69	ENSMUST00000008878.10	Gprc5b Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor, family C, group 5, member B
chr7_+_130633776 Show fit	3.67	ENSMUST00000084509.7 ENSMUST00000213064.3 ENSMUST00000208311.4	Dmbt1 Ensembl NCBI MGI UniProt Show fit	deleted in malignant brain tumors 1
chr4_-_57916283 Show fit	3.67	ENSMUST00000063816.6	D630039A03Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA D630039A03 gene
chr11_-_100012384 Show fit	3.67	ENSMUST00000007275.3	Krt13 Ensembl NCBI MGI UniProt Show fit	keratin 13
chr5_-_137919873 Show fit	3.65	ENSMUST00000031741.8	Cyp3a13 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 13
chrX_-_51702813 Show fit	3.63	ENSMUST00000114857.2	Gpc3 Ensembl NCBI MGI UniProt Show fit	glypican 3
chr3_+_27371206 Show fit	3.62	ENSMUST00000174840.2	Tnfsf10 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 10
chr11_+_98727611 Show fit	3.61	ENSMUST00000107479.3	Rapgefl1 Ensembl NCBI MGI UniProt Show fit	Rap guanine nucleotide exchange factor (GEF)-like 1
chrX_+_150961960 Show fit	3.61	ENSMUST00000096275.5	Iqsec2 Ensembl NCBI MGI UniProt Show fit	IQ motif and Sec7 domain 2
chr1_-_79838897 Show fit	3.61	ENSMUST00000190724.2	Serpine2 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade E, member 2
chr5_-_53864874 Show fit	3.58	ENSMUST00000031093.5	Cckar Ensembl NCBI MGI UniProt Show fit	cholecystokinin A receptor
chr11_+_28803188 Show fit	3.58	ENSMUST00000020759.12	Efemp1 Ensembl NCBI MGI UniProt Show fit	epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr19_+_4644425 Show fit	3.57	ENSMUST00000238089.2	Pcx Ensembl NCBI MGI UniProt Show fit	pyruvate carboxylase
chr16_+_33712305 Show fit	3.56	ENSMUST00000232262.2	Itgb5 Ensembl NCBI MGI UniProt Show fit	integrin beta 5
chr3_-_107667499 Show fit	3.52	ENSMUST00000153114.2 ENSMUST00000118593.8 ENSMUST00000120243.8	Csf1 Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 1 (macrophage)
chr2_+_118493713 Show fit	3.50	ENSMUST00000099557.10	Pak6 Ensembl NCBI MGI UniProt Show fit	p21 (RAC1) activated kinase 6
chr7_-_105131407 Show fit	3.49	ENSMUST00000047040.4	Cavin3 Ensembl NCBI MGI UniProt Show fit	caveolae associated 3
chr2_+_177834868 Show fit	3.49	ENSMUST00000103065.2	Phactr3 Ensembl NCBI MGI UniProt Show fit	phosphatase and actin regulator 3
chr17_+_71980249 Show fit	3.49	ENSMUST00000097284.10	Togaram2 Ensembl NCBI MGI UniProt Show fit	TOG array regulator of axonemal microtubules 2
chr1_+_172328768 Show fit	3.46	ENSMUST00000111228.2	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chrX_+_135171049 Show fit	3.46	ENSMUST00000113112.2	Bex3 Ensembl NCBI MGI UniProt Show fit	brain expressed X-linked 3
chr7_-_28297565 Show fit	3.45	ENSMUST00000040531.9 ENSMUST00000108283.8	Samd4b Ensembl NCBI MGI UniProt Show fit Pak4 Ensembl NCBI MGI UniProt Show fit	sterile alpha motif domain containing 4B p21 (RAC1) activated kinase 4
chr13_-_6686686 Show fit	3.43	ENSMUST00000136585.2	Pfkp Ensembl NCBI MGI UniProt Show fit	phosphofructokinase, platelet
chr4_-_115504907 Show fit	3.42	ENSMUST00000102707.10	Cyp4b1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily b, polypeptide 1
chr4_+_140966810 Show fit	3.40	ENSMUST00000141834.9	Arhgef19 Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 19
chr2_+_84880776 Show fit	3.38	ENSMUST00000111605.9	Tnks1bp1 Ensembl NCBI MGI UniProt Show fit	tankyrase 1 binding protein 1
chr3_-_89153135 Show fit	3.36	ENSMUST00000041022.15	Trim46 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 46
chr3_+_96508400 Show fit	3.34	ENSMUST00000062058.5	Lix1l Ensembl NCBI MGI UniProt Show fit	Lix1-like
chr13_-_63006176 Show fit	3.31	ENSMUST00000021907.9	Fbp2 Ensembl NCBI MGI UniProt Show fit	fructose bisphosphatase 2
chr12_+_16703383 Show fit	3.30	ENSMUST00000221596.2 ENSMUST00000111064.3 ENSMUST00000220892.2	Ntsr2 Ensembl NCBI MGI UniProt Show fit	neurotensin receptor 2
chr16_-_17394495 Show fit	3.29	ENSMUST00000231645.2 ENSMUST00000232226.2 ENSMUST00000232336.2 ENSMUST00000232385.2 ENSMUST00000231615.2 ENSMUST00000231283.2 ENSMUST00000172164.10	Slc7a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr10_-_18619658 Show fit	3.25	ENSMUST00000215836.2	Arfgef3 Ensembl NCBI MGI UniProt Show fit	ARFGEF family member 3
chr3_-_94566107 Show fit	3.20	ENSMUST00000196655.5 ENSMUST00000200407.2 ENSMUST00000006123.11 ENSMUST00000196733.5	Tuft1 Ensembl NCBI MGI UniProt Show fit	tuftelin 1
chr8_+_13485451 Show fit	3.20	ENSMUST00000167505.3 ENSMUST00000167071.9	Tmem255b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 255B
chr19_-_6134703 Show fit	3.19	ENSMUST00000161548.8	Zfpl1 Ensembl NCBI MGI UniProt Show fit	zinc finger like protein 1
chr11_+_98337655 Show fit	3.18	ENSMUST00000019456.5	Grb7 Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 7
chr19_-_34579356 Show fit	3.17	ENSMUST00000168254.3	Ifit1bl1 Ensembl NCBI MGI UniProt Show fit	interferon induced protein with tetratricpeptide repeats 1B like 1
chr1_+_75376714 Show fit	3.16	ENSMUST00000113589.8	Speg Ensembl NCBI MGI UniProt Show fit	SPEG complex locus
chr3_+_13538266 Show fit	3.15	ENSMUST00000211860.2	Ralyl Ensembl NCBI MGI UniProt Show fit	RALY RNA binding protein-like
chr9_-_21710029 Show fit	3.14	ENSMUST00000034717.7	Kank2 Ensembl NCBI MGI UniProt Show fit	KN motif and ankyrin repeat domains 2
chr19_-_5148506 Show fit	3.14	ENSMUST00000025805.8	Cnih2 Ensembl NCBI MGI UniProt Show fit	cornichon family AMPA receptor auxiliary protein 2
chr4_-_9643636 Show fit	3.13	ENSMUST00000108333.8 ENSMUST00000108334.8 ENSMUST00000108335.8 ENSMUST00000152526.8 ENSMUST00000103004.10	Asph Ensembl NCBI MGI UniProt Show fit	aspartate-beta-hydroxylase
chr9_+_44684324 Show fit	3.13	ENSMUST00000214854.3 ENSMUST00000125877.8	Ift46 Ensembl NCBI MGI UniProt Show fit	intraflagellar transport 46
chr2_+_158354716 Show fit	3.10	ENSMUST00000165398.2 ENSMUST00000099133.10	Arhgap40 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 40
chr18_+_61096660 Show fit	3.09	ENSMUST00000039904.7	Camk2a Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr17_+_37253916 Show fit	3.08	ENSMUST00000173072.2	Rnf39 Ensembl NCBI MGI UniProt Show fit	ring finger protein 39
chr8_-_37200051 Show fit	3.08	ENSMUST00000098826.10	Dlc1 Ensembl NCBI MGI UniProt Show fit	deleted in liver cancer 1
chr2_+_164327988 Show fit	3.06	ENSMUST00000109350.9	Dbndd2 Ensembl NCBI MGI UniProt Show fit	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_-_107838895 Show fit	3.06	ENSMUST00000133947.9 ENSMUST00000124215.2 ENSMUST00000106688.8 ENSMUST00000106687.9	Gstm7 Ensembl NCBI MGI UniProt Show fit	glutathione S-transferase, mu 7
chr2_+_83642910 Show fit	3.05	ENSMUST00000051454.4	Fam171b Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 171, member B
chrX_-_47123719 Show fit	3.04	ENSMUST00000039026.8	Apln Ensembl NCBI MGI UniProt Show fit	apelin
chr17_+_31515163 Show fit	3.02	ENSMUST00000235972.2 ENSMUST00000165149.3 ENSMUST00000236251.2	Slc37a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_-_162687369 Show fit	3.02	ENSMUST00000193078.6	Fmo1 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 1
chr17_+_32877851 Show fit	3.00	ENSMUST00000235086.2	Cyp4f40 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily f, polypeptide 40
chr2_+_152596075 Show fit	3.00	ENSMUST00000010020.12	Cox4i2 Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit 4I2
chr6_+_54658609 Show fit	2.99	ENSMUST00000190641.7 ENSMUST00000187701.2	Mturn Ensembl NCBI MGI UniProt Show fit	maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_-_19530714 Show fit	2.98	ENSMUST00000108449.9 ENSMUST00000043822.8	Cblc Ensembl NCBI MGI UniProt Show fit	Casitas B-lineage lymphoma c
chr7_+_81984940 Show fit	2.96	ENSMUST00000173287.8	Adamtsl3 Ensembl NCBI MGI UniProt Show fit	ADAMTS-like 3
chr9_-_15212745 Show fit	2.96	ENSMUST00000217042.2	4931406C07Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4931406C07 gene
chr11_-_3489228 Show fit	2.95	ENSMUST00000075118.10 ENSMUST00000136243.2 ENSMUST00000020721.15 ENSMUST00000170588.8	Smtn Ensembl NCBI MGI UniProt Show fit	smoothelin
chr18_+_61096597 Show fit	2.92	ENSMUST00000115295.9	Camk2a Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr9_+_88209250 Show fit	2.91	ENSMUST00000034992.8	Nt5e Ensembl NCBI MGI UniProt Show fit	5' nucleotidase, ecto
chr3_-_94693740 Show fit	2.91	ENSMUST00000153263.9 ENSMUST00000107272.7 ENSMUST00000155485.4	Cgn Ensembl NCBI MGI UniProt Show fit	cingulin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	25.2	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
3.7	18.7	GO:0050902	leukocyte adhesive activation(GO:0050902)
3.1	9.4	GO:1903896	positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
2.9	8.6	GO:0051542	elastin biosynthetic process(GO:0051542)
2.8	11.3	GO:1904209	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
2.4	7.3	GO:0030070	insulin processing(GO:0030070)
2.4	7.3	GO:0006533	aspartate catabolic process(GO:0006533)
2.4	7.1	GO:0019417	sulfur oxidation(GO:0019417)
2.3	13.9	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
2.1	12.5	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.0	9.9	GO:0060279	positive regulation of ovulation(GO:0060279)
1.8	7.2	GO:1904425	negative regulation of GTP binding(GO:1904425)
1.7	5.0	GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
1.6	8.1	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.6	7.9	GO:0072138	mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
1.6	28.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5	24.4	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
1.5	4.5	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
1.5	4.5	GO:0031104	dendrite regeneration(GO:0031104)
1.5	4.5	GO:0015825	L-serine transport(GO:0015825)
1.4	4.3	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.4	4.3	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.4	7.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.4	9.5	GO:2001205	negative regulation of osteoclast development(GO:2001205)
1.3	11.5	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.3	3.8	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.2	4.9	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.2	9.7	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
1.2	3.6	GO:0061107	seminal vesicle development(GO:0061107)
1.2	7.2	GO:0018992	germ-line sex determination(GO:0018992)
1.2	12.9	GO:0007021	tubulin complex assembly(GO:0007021)
1.2	3.5	GO:1903969	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.2	3.5	GO:1901003	negative regulation of fermentation(GO:1901003)
1.2	11.5	GO:0048251	elastic fiber assembly(GO:0048251)
1.2	3.5	GO:0098749	cerebellar neuron development(GO:0098749)
1.1	12.6	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.1	3.4	GO:0018879	biphenyl metabolic process(GO:0018879)
1.1	2.1	GO:1901204	regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.0	3.1	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
1.0	6.2	GO:0007172	signal complex assembly(GO:0007172)
1.0	11.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0	3.0	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
1.0	3.0	GO:1901662	menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
1.0	3.9	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.9	3.7	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.9	9.0	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.9	6.9	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.9	1.7	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.8	8.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.8	19.9	GO:0032060	bleb assembly(GO:0032060)
0.8	3.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.8	17.2	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.8	0.8	GO:1905072	cardiac jelly development(GO:1905072)
0.8	6.2	GO:0060313	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.8	4.6	GO:0006172	ADP biosynthetic process(GO:0006172)
0.8	4.5	GO:1902847	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7	4.4	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.7	2.9	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.7	0.7	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.7	14.1	GO:0014850	response to muscle activity(GO:0014850)
0.7	2.7	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.7	2.0	GO:0006550	isoleucine catabolic process(GO:0006550)
0.7	3.3	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.6	3.7	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.6	1.8	GO:0061622	UDP-glucose metabolic process(GO:0006011) glycolytic process through glucose-1-phosphate(GO:0061622) glycolytic process from galactose(GO:0061623)
0.6	3.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.6	3.6	GO:0090274	reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.6	5.9	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5	7.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.5	2.1	GO:0051866	general adaptation syndrome(GO:0051866)
0.5	6.8	GO:0060480	positive regulation of cell fate commitment(GO:0010455) lung goblet cell differentiation(GO:0060480) intestinal epithelial cell development(GO:0060576)
0.5	10.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.5	2.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.5	2.5	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.5	2.4	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.5	2.8	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.4	1.8	GO:0090472	dibasic protein processing(GO:0090472)
0.4	4.8	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.4	6.0	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.4	3.4	GO:0070294	renal sodium ion absorption(GO:0070294)
0.4	1.3	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4	1.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4	2.1	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.4	4.1	GO:0098881	synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4	7.7	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.4	4.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.4	1.6	GO:0090346	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.4	2.4	GO:0009624	response to nematode(GO:0009624)
0.4	2.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	9.9	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4	2.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.4	2.6	GO:0036438	maintenance of lens transparency(GO:0036438)
0.4	4.9	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4	4.5	GO:0019372	lipoxygenase pathway(GO:0019372)
0.4	0.7	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.4	2.2	GO:0061718	NADH regeneration(GO:0006735) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.4	1.1	GO:2001176	mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.4	1.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.3	1.4	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3	1.4	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3	7.2	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3	2.3	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.3	1.0	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.3	6.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.3	1.0	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.3	2.4	GO:0009313	ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3	0.9	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.3	0.9	GO:1904116	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.3	2.1	GO:0060214	endocardium formation(GO:0060214)
0.3	2.7	GO:0006102	isocitrate metabolic process(GO:0006102)
0.3	3.7	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.3	10.4	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3	3.9	GO:0006751	glutathione catabolic process(GO:0006751)
0.3	1.9	GO:0001880	Mullerian duct regression(GO:0001880)
0.3	1.9	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	1.6	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3	1.3	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.3	5.1	GO:0060134	prepulse inhibition(GO:0060134)
0.3	2.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	10.3	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.3	3.9	GO:0051451	myoblast migration(GO:0051451)
0.3	4.9	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.3	0.8	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2	1.2	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.2	0.7	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.2	8.2	GO:0048745	smooth muscle tissue development(GO:0048745)
0.2	4.4	GO:0035428	hexose transmembrane transport(GO:0035428)
0.2	1.4	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2	1.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.2	1.3	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.2	4.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	1.2	GO:0061743	motor learning(GO:0061743)
0.2	1.9	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2	6.4	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2	3.9	GO:0000338	protein deneddylation(GO:0000338)
0.2	0.4	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.2	3.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.2	1.1	GO:0001969	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.2	0.9	GO:1904970	brush border assembly(GO:1904970)
0.2	0.9	GO:0001830	trophectodermal cell fate commitment(GO:0001830)
0.2	0.7	GO:0060709	glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2	6.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.2	2.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	1.9	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.2	6.4	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2	2.6	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2	0.5	GO:1900369	negative regulation of RNA interference(GO:1900369)
0.2	4.5	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.2	4.2	GO:0042118	endothelial cell activation(GO:0042118)
0.2	0.3	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2	0.8	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2	0.5	GO:0014862	regulation of the force of skeletal muscle contraction(GO:0014728) regulation of skeletal muscle contraction by chemo-mechanical energy conversion(GO:0014862)
0.2	2.9	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.2	1.8	GO:0045760	positive regulation of action potential(GO:0045760)
0.1	6.2	GO:0034308	primary alcohol metabolic process(GO:0034308)
0.1	6.8	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.1	4.8	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.9	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	1.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	3.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	3.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	3.9	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	3.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	1.2	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	1.4	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.1	1.8	GO:0042407	cristae formation(GO:0042407)
0.1	13.9	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	0.5	GO:0002030	inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1	1.7	GO:0032099	negative regulation of appetite(GO:0032099)
0.1	0.9	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.9	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) negative regulation of cholesterol efflux(GO:0090370)
0.1	1.1	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.7	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1	1.7	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.9	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	1.1	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	2.2	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1	3.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.9	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.1	6.0	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	5.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	1.3	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	3.3	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.4	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.4	GO:1902302	regulation of potassium ion export(GO:1902302) negative regulation of potassium ion export(GO:1902303)
0.1	4.1	GO:0001755	neural crest cell migration(GO:0001755)
0.1	4.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	2.0	GO:0030574	collagen catabolic process(GO:0030574)
0.1	5.7	GO:0050919	negative chemotaxis(GO:0050919)
0.1	1.7	GO:0051923	sulfation(GO:0051923)
0.1	0.8	GO:0032098	regulation of appetite(GO:0032098)
0.1	0.7	GO:0097475	motor neuron migration(GO:0097475)
0.1	4.6	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.1	5.5	GO:0048678	response to axon injury(GO:0048678)
0.1	1.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.3	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.1	3.3	GO:0097352	autophagosome maturation(GO:0097352)
0.1	1.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	4.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.3	GO:0031268	pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269)
0.1	8.9	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.1	4.9	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	5.8	GO:0048747	muscle fiber development(GO:0048747)
0.1	2.4	GO:0030252	growth hormone secretion(GO:0030252)
0.1	6.0	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1	1.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.1	5.4	GO:0046847	filopodium assembly(GO:0046847)
0.1	11.7	GO:0046488	phosphatidylinositol metabolic process(GO:0046488)
0.1	1.4	GO:0097186	amelogenesis(GO:0097186)
0.1	0.5	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.4	GO:0032439	endosome localization(GO:0032439)
0.1	3.9	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	4.0	GO:0007405	neuroblast proliferation(GO:0007405)
0.1	0.3	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1	0.5	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1	0.7	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.1	1.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1	0.8	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1	6.7	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	0.4	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.0	13.3	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	4.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0	1.6	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.2	GO:0061162	establishment of monopolar cell polarity(GO:0061162)
0.0	3.1	GO:0032414	positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0	5.1	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	2.5	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0	1.9	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	1.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	2.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	2.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	1.0	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	3.8	GO:0007586	digestion(GO:0007586)
0.0	2.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	1.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	1.4	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	0.2	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.7	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.9	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.5	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	1.3	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	2.3	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	4.9	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.8	GO:0060325	face morphogenesis(GO:0060325)
0.0	2.6	GO:0048015	phosphatidylinositol-mediated signaling(GO:0048015)
0.0	0.7	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	1.9	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	1.6	GO:0048477	oogenesis(GO:0048477)
0.0	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.0	2.3	GO:0015992	proton transport(GO:0015992)
0.0	8.9	GO:0030855	epithelial cell differentiation(GO:0030855)
0.0	1.2	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0	5.8	GO:0048511	rhythmic process(GO:0048511)
0.0	3.2	GO:0019236	response to pheromone(GO:0019236)
0.0	0.2	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0	1.3	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.5	GO:0043171	peptide catabolic process(GO:0043171)
0.0	1.3	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	1.3	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	2.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.0	0.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.2	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.2	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	2.6	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	13.8	GO:0071953	elastic fiber(GO:0071953)
1.8	7.2	GO:1990769	proximal neuron projection(GO:1990769)
1.8	12.4	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
1.5	6.0	GO:0099573	glutamatergic postsynaptic density(GO:0099573)
1.5	25.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.4	11.3	GO:0033269	internode region of axon(GO:0033269)
1.4	4.1	GO:1902912	pyruvate kinase complex(GO:1902912)
1.3	3.8	GO:1904602	serotonin-activated cation-selective channel complex(GO:1904602)
1.3	3.8	GO:1990622	CHOP-ATF3 complex(GO:1990622)
1.3	3.8	GO:0098843	postsynaptic endocytic zone(GO:0098843)
1.2	4.8	GO:0098833	presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.0	4.1	GO:0043259	laminin-10 complex(GO:0043259)
0.9	10.3	GO:0030314	junctional membrane complex(GO:0030314)
0.9	13.8	GO:0005915	zonula adherens(GO:0005915)
0.9	3.5	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.8	10.2	GO:0097450	astrocyte end-foot(GO:0097450)
0.7	3.6	GO:0034684	integrin alphav-beta5 complex(GO:0034684)
0.7	4.1	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.7	12.9	GO:0097512	cardiac myofibril(GO:0097512)
0.6	2.9	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.5	2.7	GO:0098888	extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of postsynaptic membrane(GO:0098890)
0.4	10.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.4	7.4	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.4	5.9	GO:0000813	ESCRT I complex(GO:0000813)
0.4	4.5	GO:0097418	neurofibrillary tangle(GO:0097418)
0.4	2.4	GO:0005593	FACIT collagen trimer(GO:0005593)
0.4	24.4	GO:0031901	early endosome membrane(GO:0031901)
0.4	3.9	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.4	6.8	GO:0031045	dense core granule(GO:0031045)
0.3	4.6	GO:0001520	outer dense fiber(GO:0001520)
0.3	3.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.3	0.8	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.3	3.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	1.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	1.8	GO:0061617	MICOS complex(GO:0061617)
0.2	7.2	GO:0030057	desmosome(GO:0030057)
0.2	8.4	GO:0097546	ciliary base(GO:0097546)
0.2	3.7	GO:0042589	zymogen granule membrane(GO:0042589)
0.2	1.2	GO:0097443	sorting endosome(GO:0097443)
0.2	0.9	GO:0097454	Schwann cell microvillus(GO:0097454)
0.2	1.3	GO:0071986	Ragulator complex(GO:0071986)
0.1	1.5	GO:0097449	astrocyte projection(GO:0097449)
0.1	2.7	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	1.3	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	8.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	15.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.4	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	4.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	1.4	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	1.8	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	4.9	GO:0014704	intercalated disc(GO:0014704)
0.1	6.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	3.0	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1	1.3	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.5	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	2.5	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.3	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	2.3	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	4.5	GO:0097440	apical dendrite(GO:0097440)
0.1	4.3	GO:0097228	sperm principal piece(GO:0097228)
0.1	0.4	GO:0071821	FANCM-MHF complex(GO:0071821)
0.1	6.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	2.6	GO:0032839	autophagosome membrane(GO:0000421) dendrite cytoplasm(GO:0032839)
0.1	2.3	GO:0005922	connexon complex(GO:0005922)
0.1	9.3	GO:0031526	brush border membrane(GO:0031526)
0.1	1.8	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	9.4	GO:0005903	brush border(GO:0005903)
0.1	9.5	GO:0016528	sarcoplasm(GO:0016528)
0.1	1.9	GO:0031528	microvillus membrane(GO:0031528)
0.1	5.5	GO:0043198	dendritic shaft(GO:0043198)
0.1	28.6	GO:0043292	contractile fiber(GO:0043292)
0.1	3.2	GO:0045095	keratin filament(GO:0045095)
0.1	2.3	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	9.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	3.9	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.5	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	1.5	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	8.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	2.3	GO:0031902	late endosome membrane(GO:0031902)
0.1	9.5	GO:0005604	basement membrane(GO:0005604)
0.1	9.3	GO:0008021	synaptic vesicle(GO:0008021)
0.1	7.5	GO:0005901	caveola(GO:0005901)
0.1	3.9	GO:0008180	COP9 signalosome(GO:0008180)
0.1	2.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	5.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.1	2.2	GO:0060170	ciliary membrane(GO:0060170)
0.1	1.2	GO:1904115	axon cytoplasm(GO:1904115)
0.1	9.4	GO:0005923	bicellular tight junction(GO:0005923)
0.1	6.1	GO:0055037	recycling endosome(GO:0055037)
0.1	1.7	GO:0005682	U5 snRNP(GO:0005682)
0.1	25.0	GO:0005925	focal adhesion(GO:0005925)
0.0	7.2	GO:0005769	early endosome(GO:0005769)
0.0	3.8	GO:0005581	collagen trimer(GO:0005581)
0.0	4.7	GO:0030427	site of polarized growth(GO:0030427)
0.0	1.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	1.8	GO:0005884	actin filament(GO:0005884)
0.0	8.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	3.3	GO:0030027	lamellipodium(GO:0030027)
0.0	8.5	GO:0045177	apical part of cell(GO:0045177)
0.0	7.5	GO:0030424	axon(GO:0030424)
0.0	2.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	2.7	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	7.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.7	GO:0036064	ciliary basal body(GO:0036064)
0.0	2.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	5.1	GO:0019866	organelle inner membrane(GO:0019866)
0.0	0.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	1.2	GO:1990204	oxidoreductase complex(GO:1990204)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	25.2	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.5	13.9	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
3.0	11.9	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
2.6	7.9	GO:0016501	prostacyclin receptor activity(GO:0016501)
2.2	21.9	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
2.0	8.1	GO:0004736	pyruvate carboxylase activity(GO:0004736)
1.8	7.3	GO:0003884	D-amino-acid oxidase activity(GO:0003884)
1.5	4.6	GO:0016492	G-protein coupled neurotensin receptor activity(GO:0016492)
1.5	4.5	GO:0052871	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
1.3	6.7	GO:0051185	coenzyme transporter activity(GO:0051185)
1.3	3.8	GO:0031798	type 1 metabotropic glutamate receptor binding(GO:0031798)
1.2	3.7	GO:0035375	zymogen binding(GO:0035375)
1.2	3.5	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
1.1	6.8	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
1.1	4.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.9	3.8	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.9	13.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.9	3.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.9	6.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.9	7.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.8	5.9	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.8	4.1	GO:0004743	pyruvate kinase activity(GO:0004743)
0.8	3.8	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.8	3.0	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.7	2.9	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.7	4.9	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.7	6.9	GO:1901612	cardiolipin binding(GO:1901612)
0.7	7.9	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.6	11.2	GO:0008430	selenium binding(GO:0008430)
0.6	2.5	GO:0051381	histamine binding(GO:0051381)
0.6	2.9	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.6	2.3	GO:0033797	selenate reductase activity(GO:0033797)
0.6	14.8	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.5	2.7	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5	11.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	2.4	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.5	3.4	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.5	18.7	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.4	2.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.4	12.7	GO:0017166	vinculin binding(GO:0017166)
0.4	2.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.4	1.3	GO:0032129	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.4	9.4	GO:0002162	dystroglycan binding(GO:0002162)
0.4	1.6	GO:0016708	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.4	1.6	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4	7.5	GO:0045499	chemorepellent activity(GO:0045499)
0.4	3.9	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	4.6	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.4	7.1	GO:0038191	neuropilin binding(GO:0038191)
0.3	1.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.3	4.5	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3	1.4	GO:0043532	angiostatin binding(GO:0043532)
0.3	1.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.3	4.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.3	1.0	GO:0070025	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitric oxide binding(GO:0070026)
0.3	4.8	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3	10.5	GO:0070330	aromatase activity(GO:0070330)
0.3	1.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3	1.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.3	5.6	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	2.2	GO:0019158	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3	6.8	GO:0004622	lysophospholipase activity(GO:0004622)
0.3	7.9	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	41.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3	4.2	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3	1.8	GO:0070569	uridylyltransferase activity(GO:0070569)
0.3	11.6	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3	2.8	GO:0070324	thyroid hormone binding(GO:0070324)
0.3	0.8	GO:0035939	microsatellite binding(GO:0035939)
0.3	2.5	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2	7.4	GO:0005123	death receptor binding(GO:0005123)
0.2	10.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	0.7	GO:0005333	acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.2	1.9	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.2	1.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.2	4.1	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	0.7	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.2	4.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.2	2.7	GO:0032051	clathrin light chain binding(GO:0032051)
0.2	11.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.2	0.6	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.2	4.5	GO:0042379	chemokine receptor binding(GO:0042379)
0.2	1.2	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	1.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2	3.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.2	3.3	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.2	1.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2	6.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	6.2	GO:0008432	JUN kinase binding(GO:0008432)
0.2	1.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.2	2.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	5.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	2.2	GO:0051378	serotonin binding(GO:0051378)
0.2	4.5	GO:0051787	misfolded protein binding(GO:0051787)
0.2	1.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2	4.4	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.2	2.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.2	0.5	GO:0003692	left-handed Z-DNA binding(GO:0003692)
0.2	8.9	GO:0001786	phosphatidylserine binding(GO:0001786)
0.2	4.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2	6.7	GO:0030506	ankyrin binding(GO:0030506)
0.2	10.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	4.9	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.1	1.2	GO:0004046	aminoacylase activity(GO:0004046)
0.1	1.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	4.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	8.8	GO:0005158	insulin receptor binding(GO:0005158)
0.1	13.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	14.1	GO:0035254	glutamate receptor binding(GO:0035254)
0.1	10.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	22.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.9	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.1	2.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.8	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.9	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	4.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	2.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	4.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	1.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	0.4	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	1.4	GO:0050700	CARD domain binding(GO:0050700)
0.1	2.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	1.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1	0.8	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	2.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	1.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	1.3	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.7	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	3.0	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	4.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	3.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	2.7	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	1.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	1.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.3	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1	1.0	GO:0070411	I-SMAD binding(GO:0070411)
0.1	4.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	4.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.4	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1	1.2	GO:0016594	glycine binding(GO:0016594)
0.1	0.3	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.1	1.1	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	0.6	GO:0034235	GPI anchor binding(GO:0034235)
0.1	1.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.7	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	1.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	6.9	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.1	1.2	GO:0030957	Tat protein binding(GO:0030957)
0.1	2.4	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	1.2	GO:0050811	GABA receptor binding(GO:0050811)
0.1	3.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	1.7	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	9.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	0.8	GO:0035497	cAMP response element binding(GO:0035497)
0.1	2.1	GO:0008198	ferrous iron binding(GO:0008198)
0.1	0.5	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.1	1.5	GO:0009975	cyclase activity(GO:0009975)
0.1	1.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.1	GO:0001848	complement binding(GO:0001848)
0.1	1.3	GO:0003680	AT DNA binding(GO:0003680)
0.1	2.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.8	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	1.3	GO:0047555	cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	3.3	GO:0005080	protein kinase C binding(GO:0005080)
0.0	2.9	GO:0016247	channel regulator activity(GO:0016247)
0.0	0.3	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.8	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.5	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	22.5	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	2.8	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	12.5	GO:0045296	cadherin binding(GO:0045296)
0.0	2.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.9	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	2.9	GO:0005178	integrin binding(GO:0005178)
0.0	2.1	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	1.6	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	1.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.9	GO:0042056	chemoattractant activity(GO:0042056)
0.0	4.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	4.4	GO:0005516	calmodulin binding(GO:0005516)
0.0	4.4	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	2.9	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	0.9	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	2.6	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	25.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.5	37.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.5	18.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.3	9.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	20.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	5.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	4.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	3.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	12.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	12.1	NABA COLLAGENS	Genes encoding collagen proteins
0.2	42.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	4.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	6.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	6.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	27.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	1.9	PID ALK2 PATHWAY	ALK2 signaling events
0.1	7.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	1.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	26.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	7.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	4.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	1.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	3.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	1.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	9.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.7	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.0	PID FGF PATHWAY	FGF signaling pathway
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	23.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5	25.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.4	5.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.4	5.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.4	6.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	18.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	31.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	8.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.3	14.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	7.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	4.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	10.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	1.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.3	3.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	5.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	12.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.2	6.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	7.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	9.5	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.2	7.8	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.2	4.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	11.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	7.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	14.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	4.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	3.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	0.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	3.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.2	4.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	3.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	3.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	3.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	31.3	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	3.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	4.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.8	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	10.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.6	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	1.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	4.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	1.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	0.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	2.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	3.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	1.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	2.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	2.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	1.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	5.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	1.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	1.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	4.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	2.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	2.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.1	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.8	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization

Results for Nfic_Nfib

Z-value: 2.07

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Transcription factors associated with Nfic_Nfib

Activity-expression correlation:

Activity profile of Nfic_Nfib motif

Sorted Z-values of Nfic_Nfib motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfic_Nfib

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: