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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfil3_Tef

Z-value: 2.52

Motif logo

Transcription factors associated with Nfil3_Tef

Gene Symbol Gene ID Gene Info
ENSMUSG00000056749.8 Nfil3
ENSMUSG00000022389.16 Tef

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tefmm39_v1_chr15_+_81686622_816867790.671.3e-10Click!
Nfil3mm39_v1_chr13_-_53135064_531351140.381.1e-03Click!

Activity profile of Nfil3_Tef motif

Sorted Z-values of Nfil3_Tef motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfil3_Tef

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_26006594 29.79 ENSMUST00000098657.5
cytochrome P450, family 2, subfamily a, polypeptide 4
chr14_+_40827317 28.21 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr6_-_113911640 27.49 ENSMUST00000101044.9
ATPase, Ca++ transporting, plasma membrane 2
chr14_+_40826970 26.17 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr14_+_66208498 25.57 ENSMUST00000128539.8
clusterin
chr13_-_25454058 24.65 ENSMUST00000057866.13
neurensin 1
chr6_-_55658242 23.78 ENSMUST00000044767.10
neurogenic differentiation 6
chr14_+_40827108 23.08 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr14_+_66208253 22.93 ENSMUST00000138191.8
clusterin
chr5_+_90608751 22.77 ENSMUST00000031314.10
albumin
chr19_-_38113696 22.53 ENSMUST00000025951.14
ENSMUST00000237287.2
retinol binding protein 4, plasma
chr19_-_41065544 22.36 ENSMUST00000087176.8
oligodendrocytic myelin paranodal and inner loop protein
chr14_+_66208059 22.19 ENSMUST00000127387.8
clusterin
chr7_+_26534730 22.10 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr14_+_66208613 20.77 ENSMUST00000144619.2
clusterin
chr12_-_81014849 19.93 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_+_22769822 18.87 ENSMUST00000023590.9
histidine-rich glycoprotein
chr14_+_60615128 18.71 ENSMUST00000022561.9
APC membrane recruitment 2
chr11_-_43792013 18.17 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chr2_-_66271097 18.01 ENSMUST00000112371.9
ENSMUST00000138910.3
sodium channel, voltage-gated, type I, alpha
chr2_+_102536701 17.96 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_+_101276474 17.27 ENSMUST00000102780.8
ENSMUST00000106946.8
ENSMUST00000106945.8
adenylate kinase 4
chr3_-_113368407 17.26 ENSMUST00000106540.8
amylase 1, salivary
chr12_-_81014755 17.05 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr4_+_101276893 16.78 ENSMUST00000131397.2
ENSMUST00000133055.8
adenylate kinase 4
chr16_+_22769844 15.84 ENSMUST00000232422.2
histidine-rich glycoprotein
chr2_-_25359752 15.07 ENSMUST00000114259.3
ENSMUST00000015234.13
prostaglandin D2 synthase (brain)
chr1_-_91386976 14.96 ENSMUST00000069620.10
period circadian clock 2
chr4_+_85123654 14.51 ENSMUST00000030212.15
ENSMUST00000107189.8
ENSMUST00000107184.8
SH3-domain GRB2-like 2
chr8_-_93857899 13.47 ENSMUST00000034189.17
carboxylesterase 1C
chr17_+_26028059 13.47 ENSMUST00000045692.9
F-box and leucine-rich repeat protein 16
chr4_+_101365052 13.43 ENSMUST00000038207.12
DnaJ heat shock protein family (Hsp40) member C6
chr7_+_143729250 13.38 ENSMUST00000105900.9
SH3 and multiple ankyrin repeat domains 2
chr16_+_22710785 13.22 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr2_-_25360043 13.17 ENSMUST00000114251.8
prostaglandin D2 synthase (brain)
chr4_+_101365144 12.86 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr2_+_135899847 11.75 ENSMUST00000057503.7
lysosomal-associated membrane protein family, member 5
chr17_+_44112679 11.18 ENSMUST00000229744.2
regulator of calcineurin 2
chr5_-_89605622 11.07 ENSMUST00000049209.13
vitamin D binding protein
chr19_-_34724689 11.02 ENSMUST00000009522.4
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr1_-_58625350 10.83 ENSMUST00000038372.14
ENSMUST00000097724.10
family with sequence similarity 126, member B
chr2_+_131751848 10.73 ENSMUST00000091288.13
ENSMUST00000124100.8
ENSMUST00000136783.2
prion protein
prion protein readthrough transcript
chrX_-_50770580 10.29 ENSMUST00000088172.12
heparan sulfate 6-O-sulfotransferase 2
chrX_-_50770733 10.17 ENSMUST00000114871.2
heparan sulfate 6-O-sulfotransferase 2
chr3_+_129326285 9.95 ENSMUST00000197235.5
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr2_-_110781268 9.87 ENSMUST00000099623.10
anoctamin 3
chr2_-_102282844 9.83 ENSMUST00000099678.5
four jointed box 1
chr11_+_78181667 9.81 ENSMUST00000046361.5
ENSMUST00000238934.2
ribosomal protein S6 kinase related
chr15_+_68800261 9.77 ENSMUST00000022954.7
KH domain containing, RNA binding, signal transduction associated 3
chr12_+_117621644 9.63 ENSMUST00000222105.2
Rap guanine nucleotide exchange factor (GEF) 5
chr4_+_85123358 9.43 ENSMUST00000107188.10
SH3-domain GRB2-like 2
chr11_-_101979297 9.40 ENSMUST00000017458.11
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr4_-_60538151 9.29 ENSMUST00000098047.3
major urinary protein 10
chr10_-_31321793 9.19 ENSMUST00000213639.2
ENSMUST00000215515.2
ENSMUST00000214644.2
ENSMUST00000213528.2
tumor protein D52-like 1
chr1_+_172525613 9.15 ENSMUST00000038495.5
C-reactive protein, pentraxin-related
chr3_+_96088467 8.99 ENSMUST00000035371.9
synaptic vesicle glycoprotein 2 a
chr6_+_133082202 8.74 ENSMUST00000191462.2
small integral membrane protein 10 like 1
chr6_+_106095726 8.64 ENSMUST00000113258.8
ENSMUST00000079416.6
contactin 4
chr18_+_23937019 8.61 ENSMUST00000025127.5
microtubule-associated protein, RP/EB family, member 2
chr1_-_164281344 8.56 ENSMUST00000193367.2
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_-_104733580 8.56 ENSMUST00000064873.9
ENSMUST00000106808.10
ENSMUST00000048947.15
complement component 8, alpha polypeptide
chr7_+_95860863 8.53 ENSMUST00000107165.8
teneurin transmembrane protein 4
chr4_-_41774097 8.45 ENSMUST00000108036.8
ENSMUST00000108037.9
ENSMUST00000108032.3
ENSMUST00000173865.9
ENSMUST00000155240.2
chemokine (C-C motif) ligand 27A
chr14_+_60615690 8.38 ENSMUST00000239079.2
APC membrane recruitment 2
chr9_+_21848282 8.31 ENSMUST00000046371.13
phospholipid phosphatase related 2
chr3_+_141170941 8.28 ENSMUST00000106236.9
unc-5 netrin receptor C
chr7_+_119125443 8.05 ENSMUST00000207440.2
acyl-CoA synthetase medium-chain family member 5
chr15_-_8739893 7.95 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_11063678 7.71 ENSMUST00000027056.12
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr15_-_33687986 7.70 ENSMUST00000042021.5
testis-specific protein, Y-encoded-like 5
chr13_+_76727787 7.69 ENSMUST00000126960.8
ENSMUST00000109583.9
multiple C2 domains, transmembrane 1
chr7_+_119125426 7.69 ENSMUST00000066465.3
acyl-CoA synthetase medium-chain family member 5
chr7_+_119125546 7.43 ENSMUST00000207387.2
ENSMUST00000207813.2
acyl-CoA synthetase medium-chain family member 5
chr3_-_88669551 7.22 ENSMUST00000183267.2
synaptotagmin XI
chr2_+_129642371 7.14 ENSMUST00000165413.9
ENSMUST00000166282.3
serine/threonine kinase 35
chr11_+_4014841 7.11 ENSMUST00000068322.7
SEC14-like lipid binding 3
chr1_-_140111138 6.88 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr13_+_43019718 6.88 ENSMUST00000131942.2
phosphatase and actin regulator 1
chr18_+_37453427 6.87 ENSMUST00000078271.4
protocadherin beta 5
chr3_+_30847024 6.81 ENSMUST00000029256.9
SEC62 homolog (S. cerevisiae)
chr3_+_59939175 6.75 ENSMUST00000029325.5
arylacetamide deacetylase
chr14_-_28691423 6.71 ENSMUST00000225985.2
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr16_-_22258320 6.65 ENSMUST00000170393.2
ets variant 5
chr15_-_8740218 6.63 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_-_78300802 6.62 ENSMUST00000041616.15
pyridoxal (pyridoxine, vitamin B6) kinase
chr14_+_4230569 6.55 ENSMUST00000090543.6
nuclear receptor subfamily 1, group D, member 2
chr13_+_4624074 6.54 ENSMUST00000021628.4
aldo-keto reductase family 1, member C21
chr1_-_140111018 6.34 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr8_+_59365291 6.24 ENSMUST00000160055.2
cDNA sequence BC030500
chr19_+_31846154 6.21 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
APOBEC1 complementation factor
chr19_-_42420216 6.21 ENSMUST00000048630.8
ENSMUST00000238290.2
cartilage acidic protein 1
chr2_+_3115250 6.15 ENSMUST00000072955.12
family with sequence similarity 171, member A1
chr13_+_25127127 6.07 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr19_+_23118545 6.07 ENSMUST00000036884.3
Kruppel-like factor 9
chr19_-_7779943 6.06 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr2_-_66240408 6.05 ENSMUST00000112366.8
sodium channel, voltage-gated, type I, alpha
chr15_+_39255185 6.04 ENSMUST00000228839.2
regulating synaptic membrane exocytosis 2
chr13_-_4200627 5.94 ENSMUST00000110704.9
ENSMUST00000021635.9
aldo-keto reductase family 1, member C18
chr3_+_141171347 5.90 ENSMUST00000130636.8
unc-5 netrin receptor C
chr10_-_31321938 5.81 ENSMUST00000000305.7
tumor protein D52-like 1
chr19_-_7780025 5.77 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr12_+_29584560 5.76 ENSMUST00000021009.10
myelin transcription factor 1-like
chr4_-_151129020 5.67 ENSMUST00000103204.11
period circadian clock 3
chr10_-_49659355 5.67 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr12_-_41536430 5.65 ENSMUST00000043884.6
leucine rich repeat protein 3, neuronal
chr16_-_22258469 5.61 ENSMUST00000079601.13
ets variant 5
chr4_+_41941572 5.57 ENSMUST00000108028.9
ENSMUST00000153997.8
predicted gene, 20878
chr17_-_90395771 5.53 ENSMUST00000197268.5
ENSMUST00000173917.8
neurexin I
chr10_-_125144678 5.51 ENSMUST00000105257.4
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr12_+_37291632 5.47 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr2_-_131170902 5.46 ENSMUST00000110194.8
ring finger protein 24
chr3_-_123483772 5.44 ENSMUST00000172537.3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr12_+_37292029 5.40 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr3_-_98660781 5.24 ENSMUST00000094050.11
ENSMUST00000090743.13
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr15_-_76191301 5.17 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr3_+_141171322 5.16 ENSMUST00000075282.10
unc-5 netrin receptor C
chr7_+_91711600 5.12 ENSMUST00000098308.4
discs large MAGUK scaffold protein 2
chr5_-_130053120 5.12 ENSMUST00000161640.8
ENSMUST00000161884.2
ENSMUST00000161094.8
argininosuccinate lyase
chr14_+_4230658 4.94 ENSMUST00000225491.2
nuclear receptor subfamily 1, group D, member 2
chr1_+_55091922 4.89 ENSMUST00000087617.11
ENSMUST00000027125.7
coenzyme Q10B
chr10_-_6930376 4.89 ENSMUST00000105617.8
interaction protein for cytohesin exchange factors 1
chr13_+_16186410 4.86 ENSMUST00000042603.14
inhibin beta-A
chr7_+_90125890 4.80 ENSMUST00000208919.2
discs large MAGUK scaffold protein 2
chr4_-_110143777 4.80 ENSMUST00000138972.8
ELAV like RNA binding protein 4
chr9_-_78254422 4.76 ENSMUST00000034902.12
glutathione S-transferase, alpha 2 (Yc2)
chr10_+_23727325 4.74 ENSMUST00000020190.8
vanin 3
chr6_+_103674695 4.70 ENSMUST00000205098.2
cell adhesion molecule L1-like
chr16_+_3702493 4.65 ENSMUST00000176233.2
predicted gene 20695
chr9_-_78254443 4.60 ENSMUST00000129247.2
glutathione S-transferase, alpha 2 (Yc2)
chr19_+_34560922 4.50 ENSMUST00000102825.4
interferon-induced protein with tetratricopeptide repeats 3
chr16_+_3702604 4.46 ENSMUST00000115860.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr18_+_37875135 4.45 ENSMUST00000003599.9
protocadherin gamma subfamily B, 6
chr5_-_5564730 4.42 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr10_+_86599836 4.40 ENSMUST00000218802.2
predicted gene, 49358
chr8_-_93806593 4.37 ENSMUST00000109582.3
carboxylesterase 1B
chrX_-_166907286 4.33 ENSMUST00000239138.2
FERM and PDZ domain containing 4
chr8_-_91860655 4.27 ENSMUST00000125257.3
AKT interacting protein
chr18_+_37130860 4.26 ENSMUST00000115659.6
protocadherin alpha 9
chr2_-_131953359 4.24 ENSMUST00000128899.2
solute carrier family 23 (nucleobase transporters), member 2
chr19_+_4560500 4.23 ENSMUST00000068004.13
ENSMUST00000224726.3
pyruvate carboxylase
chr4_+_43383449 4.22 ENSMUST00000135216.2
ENSMUST00000152322.8
RUN and SH3 domain containing 2
chr16_+_3702523 4.22 ENSMUST00000176625.8
ENSMUST00000186375.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr15_-_93234681 4.18 ENSMUST00000080299.7
YY1 associated factor 2
chr7_+_27353331 4.17 ENSMUST00000008088.9
tetratricopeptide repeat domain 9B
chr2_+_85715984 4.12 ENSMUST00000213441.3
olfactory receptor 1023
chr9_+_32305259 4.08 ENSMUST00000172015.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr4_+_42438970 3.99 ENSMUST00000238328.2
predicted gene, 21586
chr4_-_47474283 3.83 ENSMUST00000044148.3
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr5_-_145406533 3.81 ENSMUST00000031633.5
cytochrome P450, family 3, subfamily a, polypeptide 16
chr11_-_101676076 3.77 ENSMUST00000164750.8
ENSMUST00000107176.8
ENSMUST00000017868.7
ets variant 4
chr9_-_54554483 3.73 ENSMUST00000128163.8
acyl-CoA synthetase bubblegum family member 1
chr18_+_37063237 3.72 ENSMUST00000193839.6
ENSMUST00000070797.7
protocadherin alpha 1
chr10_-_63926044 3.69 ENSMUST00000105439.2
leucine rich repeat transmembrane neuronal 3
chr3_+_114697710 3.65 ENSMUST00000081752.13
olfactomedin 3
chr7_-_103832599 3.61 ENSMUST00000216612.3
olfactory receptor 648
chr8_+_46944000 3.59 ENSMUST00000110372.9
ENSMUST00000130563.2
acyl-CoA synthetase long-chain family member 1
chr18_+_37125424 3.58 ENSMUST00000194038.2
protocadherin alpha 8
chr19_-_59931432 3.58 ENSMUST00000170819.2
RAB11 family interacting protein 2 (class I)
chr11_-_83959175 3.55 ENSMUST00000100705.11
dual specificity phosphatase 14
chr12_+_37291728 3.54 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr5_-_5564873 3.49 ENSMUST00000060947.14
claudin 12
chr15_+_101152078 3.49 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr2_+_54326329 3.48 ENSMUST00000112636.8
ENSMUST00000112635.8
ENSMUST00000112634.8
polypeptide N-acetylgalactosaminyltransferase 13
chr2_-_60114684 3.48 ENSMUST00000028356.9
ENSMUST00000074606.11
CD302 antigen
chr12_+_36431449 3.41 ENSMUST00000221452.2
ENSMUST00000062041.6
ENSMUST00000220519.2
ENSMUST00000221895.2
CDP-L-ribitol pyrophosphorylase A
chr17_+_47604995 3.38 ENSMUST00000190020.4
transcriptional regulating factor 1
chr2_-_130884602 3.36 ENSMUST00000028787.12
ENSMUST00000110239.8
ENSMUST00000110234.8
glial cell line derived neurotrophic factor family receptor alpha 4
chr1_-_14380327 3.35 ENSMUST00000080664.14
EYA transcriptional coactivator and phosphatase 1
chr15_+_16728842 3.30 ENSMUST00000228307.2
cadherin 9
chr8_-_91860576 3.29 ENSMUST00000120213.9
ENSMUST00000109609.9
AKT interacting protein
chr12_+_87247297 3.24 ENSMUST00000182869.2
sterile alpha motif domain containing 15
chr15_-_37007623 3.19 ENSMUST00000078976.9
zinc finger protein 706
chrX_-_74426221 3.10 ENSMUST00000147349.8
coagulation factor VIII
chr8_-_93924426 3.09 ENSMUST00000034172.8
carboxylesterase 1D
chr11_-_115977755 3.08 ENSMUST00000074628.13
ENSMUST00000106444.4
WW domain binding protein 2
chr10_+_80134917 3.08 ENSMUST00000154212.8
APC regulator of WNT signaling pathway 2
chr1_-_14380418 3.04 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1
chr9_+_40180497 3.03 ENSMUST00000049941.12
sodium channel, voltage-gated, type III, beta
chr9_+_78099229 3.02 ENSMUST00000034903.7
glutathione S-transferase, alpha 4
chr5_+_67126304 3.00 ENSMUST00000132991.5
LIM and calponin homology domains 1
chr17_-_80885197 2.92 ENSMUST00000234602.2
cyclin-dependent kinase-like 4
chr2_-_20948230 2.92 ENSMUST00000140230.2
Rho GTPase activating protein 21
chr3_+_84859453 2.89 ENSMUST00000029727.8
F-box and WD-40 domain protein 7
chr16_-_59138611 2.86 ENSMUST00000216261.2
olfactory receptor 204
chr11_-_106107132 2.82 ENSMUST00000002043.10
coiled-coil domain containing 47
chr1_-_38937190 2.82 ENSMUST00000193435.6
ENSMUST00000194361.6
carbohydrate sulfotransferase 10
chr10_+_20046748 2.80 ENSMUST00000215924.2
microtubule-associated protein 7
chr15_+_7159038 2.77 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr9_+_40180569 2.75 ENSMUST00000176185.8
sodium channel, voltage-gated, type III, beta
chr4_+_42293921 2.75 ENSMUST00000238203.2
predicted gene, 21953
chr4_+_43493344 2.74 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr8_+_22550727 2.72 ENSMUST00000072572.13
ENSMUST00000110737.3
ENSMUST00000131624.2
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr2_+_118692435 2.71 ENSMUST00000028807.6
isovaleryl coenzyme A dehydrogenase
chr5_+_117979899 2.71 ENSMUST00000142742.9
nitric oxide synthase 1, neuronal
chr19_-_60849828 2.70 ENSMUST00000135808.8
sideroflexin 4
chr15_+_41694317 2.70 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr4_+_40473130 2.63 ENSMUST00000179526.2
transmembrane protein 215
chr14_+_3576275 2.61 ENSMUST00000151926.8
ubiquitin-conjugating enzyme E2E 2
chrX_+_111510223 2.56 ENSMUST00000113409.8
zinc finger protein 711
chr5_-_148931957 2.56 ENSMUST00000147473.6
predicted gene 42791

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.8 77.5 GO:0009087 methionine catabolic process(GO:0009087)
15.2 91.5 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
11.6 34.7 GO:0097037 heme export(GO:0097037)
7.6 22.8 GO:0051659 maintenance of mitochondrion location(GO:0051659)
6.1 18.2 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
5.0 15.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
4.7 28.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
4.6 32.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
4.5 22.5 GO:0048807 female genitalia morphogenesis(GO:0048807)
4.4 26.3 GO:0072318 clathrin coat disassembly(GO:0072318)
3.9 27.5 GO:0048840 otolith development(GO:0048840)
3.7 11.0 GO:0015881 creatine transport(GO:0015881)
3.6 10.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
3.4 20.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
3.0 23.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
2.9 8.6 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
2.2 6.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
2.2 6.6 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
2.1 19.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
2.1 8.5 GO:0060912 cardiac cell fate specification(GO:0060912)
2.0 5.9 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.9 26.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.9 62.7 GO:0035634 response to stilbenoid(GO:0035634)
1.8 7.2 GO:1905154 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
1.8 19.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.7 5.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.7 8.5 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
1.6 16.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.6 6.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
1.4 34.0 GO:0046033 AMP metabolic process(GO:0046033)
1.4 4.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.4 9.9 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.1 9.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.1 14.4 GO:0046485 ether lipid metabolic process(GO:0046485)
1.0 34.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.0 7.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.0 3.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.0 4.9 GO:0060279 positive regulation of ovulation(GO:0060279)
1.0 8.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9 5.5 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.9 23.8 GO:0021542 dentate gyrus development(GO:0021542)
0.8 4.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 9.9 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.8 11.8 GO:0015747 urate transport(GO:0015747)
0.7 2.7 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.7 7.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 2.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.6 9.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.6 1.9 GO:0006550 isoleucine catabolic process(GO:0006550)
0.6 5.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 4.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.6 2.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.6 2.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.6 8.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 3.8 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.5 1.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.5 1.6 GO:0019085 early viral transcription(GO:0019085)
0.5 2.6 GO:0006041 glucosamine metabolic process(GO:0006041)
0.5 5.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5 1.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5 6.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.5 3.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.5 1.5 GO:1904268 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.5 4.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.5 6.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.5 9.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.5 1.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 1.5 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.5 4.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.5 13.4 GO:0071625 vocalization behavior(GO:0071625)
0.4 3.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 1.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 11.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 13.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.4 3.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 6.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 6.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.4 7.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.4 11.5 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.4 2.5 GO:0006083 acetate metabolic process(GO:0006083)
0.3 2.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.3 2.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 3.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.3 1.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 1.8 GO:1903758 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3 2.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.3 3.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.3 2.7 GO:0006551 leucine metabolic process(GO:0006551)
0.3 1.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 1.9 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 9.8 GO:0010842 retina layer formation(GO:0010842)
0.2 1.2 GO:0060356 leucine import(GO:0060356)
0.2 23.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 4.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 2.8 GO:0006983 ER overload response(GO:0006983)
0.2 2.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.9 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.2 5.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 7.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 1.8 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 2.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 1.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 2.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 8.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 0.8 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.2 0.6 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 3.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 2.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 9.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 7.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 7.1 GO:0007616 long-term memory(GO:0007616)
0.1 3.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 7.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 4.7 GO:0035640 exploration behavior(GO:0035640)
0.1 18.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 5.7 GO:0048665 neuron fate specification(GO:0048665)
0.1 3.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 2.8 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.8 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 4.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 9.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 0.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.8 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 1.3 GO:0046174 inositol metabolic process(GO:0006020) polyol catabolic process(GO:0046174)
0.1 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.4 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.1 3.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 5.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.4 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 5.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 2.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.5 GO:0032402 melanosome transport(GO:0032402)
0.1 9.9 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 3.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 0.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 3.6 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.0 4.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 5.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 3.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 6.3 GO:0007416 synapse assembly(GO:0007416)
0.0 8.6 GO:0007411 axon guidance(GO:0007411)
0.0 5.6 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 4.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.6 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.0 3.1 GO:0019236 response to pheromone(GO:0019236)
0.0 2.3 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 34.7 GO:0061474 phagolysosome membrane(GO:0061474)
6.1 91.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.6 4.9 GO:0043512 inhibin A complex(GO:0043512)
1.3 12.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.1 29.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.1 7.6 GO:0070695 FHF complex(GO:0070695)
1.0 27.5 GO:0098839 postsynaptic density membrane(GO:0098839)
1.0 13.4 GO:0005883 neurofilament(GO:0005883)
1.0 8.6 GO:0005579 membrane attack complex(GO:0005579)
0.9 8.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 6.2 GO:0045293 mRNA editing complex(GO:0045293)
0.7 2.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 5.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 50.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 77.5 GO:0016363 nuclear matrix(GO:0016363)
0.5 7.2 GO:0032009 early phagosome(GO:0032009)
0.4 5.2 GO:0070852 cell body fiber(GO:0070852)
0.4 1.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 9.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 8.6 GO:0035371 microtubule plus-end(GO:0035371)
0.3 5.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 37.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.3 13.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 29.1 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 5.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 2.3 GO:0097542 ciliary tip(GO:0097542)
0.2 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.2 20.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 60.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 1.4 GO:0070552 BRISC complex(GO:0070552)
0.2 5.8 GO:0060077 inhibitory synapse(GO:0060077)
0.2 2.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 41.1 GO:0072562 blood microparticle(GO:0072562)
0.2 40.1 GO:0030426 growth cone(GO:0030426)
0.1 2.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 4.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 3.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 36.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 5.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 7.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 31.5 GO:0005769 early endosome(GO:0005769)
0.1 2.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 19.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 3.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 5.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 6.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.0 GO:0000786 nucleosome(GO:0000786)
0.1 9.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 16.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 4.3 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 21.0 GO:0045202 synapse(GO:0045202)
0.0 4.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 9.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.0 37.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 9.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 6.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.8 GO:0043235 receptor complex(GO:0043235)
0.0 5.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 13.9 GO:0016604 nuclear body(GO:0016604)
0.0 2.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.4 77.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
11.3 34.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
7.5 22.5 GO:0034632 retinol transporter activity(GO:0034632)
7.1 28.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
6.5 6.5 GO:1902121 lithocholic acid binding(GO:1902121)
5.4 32.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
5.1 20.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
4.8 14.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
4.6 37.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
4.5 18.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
3.9 27.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
3.7 11.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
3.5 91.5 GO:0051787 misfolded protein binding(GO:0051787)
2.9 23.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
2.8 11.1 GO:1902271 D3 vitamins binding(GO:1902271)
2.4 19.3 GO:0005042 netrin receptor activity(GO:0005042)
2.4 7.1 GO:0016232 HNK-1 sulfotransferase activity(GO:0016232)
2.2 6.6 GO:0070279 vitamin B6 binding(GO:0070279)
2.2 13.2 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
2.1 10.7 GO:1903135 cupric ion binding(GO:1903135)
2.0 5.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.9 13.2 GO:0001851 complement component C3b binding(GO:0001851)
1.4 4.2 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.3 5.1 GO:0016842 amidine-lyase activity(GO:0016842)
1.3 3.8 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.2 11.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 17.3 GO:0031404 chloride ion binding(GO:0031404)
1.2 18.8 GO:0015643 toxic substance binding(GO:0015643)
1.1 9.2 GO:0001849 complement component C1q binding(GO:0001849)
1.1 32.6 GO:0031402 sodium ion binding(GO:0031402)
1.1 4.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.0 7.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.0 3.1 GO:0004771 sterol esterase activity(GO:0004771)
1.0 36.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.9 5.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.9 11.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.8 15.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.8 9.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.8 2.5 GO:0019807 aspartoacylase activity(GO:0019807)
0.8 5.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.8 5.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.8 3.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.7 9.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7 11.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.7 5.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 3.6 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.7 4.9 GO:0048039 ubiquinone binding(GO:0048039)
0.7 4.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.7 2.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.7 6.1 GO:0004630 phospholipase D activity(GO:0004630)
0.7 3.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.7 8.6 GO:0001848 complement binding(GO:0001848)
0.6 2.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6 4.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 8.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.6 5.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 2.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 4.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 2.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.5 3.8 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.5 2.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.4 3.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 2.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 1.6 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 2.4 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.4 9.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 8.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 1.6 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.4 6.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 5.8 GO:0050897 cobalt ion binding(GO:0050897)
0.3 9.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3 7.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 9.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 31.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 13.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.3 2.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.3 0.8 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.3 1.9 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 1.3 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.3 3.1 GO:0008061 chitin binding(GO:0008061)
0.3 29.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 1.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.3 9.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.7 GO:0102391 very long-chain fatty acid-CoA ligase activity(GO:0031957) decanoate--CoA ligase activity(GO:0102391)
0.2 37.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 2.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 6.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 2.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.6 GO:0042979 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.2 1.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.7 GO:0000182 rDNA binding(GO:0000182)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 7.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 2.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 4.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 6.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 13.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 13.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 9.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 2.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.5 GO:0050699 WW domain binding(GO:0050699)
0.0 8.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 4.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 3.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 3.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.3 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 10.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 12.4 GO:0005549 odorant binding(GO:0005549)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 9.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 10.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 4.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 1.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 8.6 GO:0008289 lipid binding(GO:0008289)
0.0 1.3 GO:0051117 ATPase binding(GO:0051117)
0.0 1.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 74.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.6 15.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 23.9 PID RHOA PATHWAY RhoA signaling pathway
0.3 22.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 21.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 12.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 10.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 10.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 13.2 PID BMP PATHWAY BMP receptor signaling
0.2 19.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 4.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 4.9 PID ALK1 PATHWAY ALK1 signaling events
0.2 14.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 6.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.9 PID MYC PATHWAY C-MYC pathway
0.1 2.2 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.8 PID LKB1 PATHWAY LKB1 signaling events
0.1 19.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 59.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
2.3 77.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.3 48.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.2 27.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.1 9.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.0 21.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.0 129.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 25.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 19.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 13.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 33.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 5.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 21.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 15.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 14.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 9.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 14.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 8.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 7.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 2.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 8.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 6.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 15.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 10.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 5.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 7.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.3 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 3.6 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 2.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 3.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 2.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 5.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 3.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 3.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing