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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfix

Z-value: 1.58

Motif logo

Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info
ENSMUSG00000001911.17 Nfix

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfixmm39_v1_chr8_-_85500998_855011080.721.6e-12Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_63006176 19.36 ENSMUST00000021907.9
fructose bisphosphatase 2
chr7_+_130633776 12.30 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr7_+_130179063 12.21 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr11_-_100012384 10.80 ENSMUST00000007275.3
keratin 13
chr3_-_69767208 10.29 ENSMUST00000171529.4
ENSMUST00000051239.13
serine palmitoyltransferase, small subunit B
chr5_+_115604321 9.54 ENSMUST00000145785.8
ENSMUST00000031495.11
ENSMUST00000112071.8
ENSMUST00000125568.2
phospholipase A2, group IB, pancreas
chr17_-_82045800 9.49 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_-_87054796 9.46 ENSMUST00000031181.16
ENSMUST00000113333.2
UDP glucuronosyltransferase 2 family, polypeptide B34
chr5_-_24829395 8.73 ENSMUST00000195943.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_-_76842263 8.50 ENSMUST00000082431.6
glutathione peroxidase 2
chr3_-_144738526 8.38 ENSMUST00000029919.7
chloride channel accessory 1
chr15_-_101833160 7.90 ENSMUST00000023797.8
keratin 4
chr11_+_52265090 7.61 ENSMUST00000020673.3
voltage-dependent anion channel 1
chr14_+_70694887 7.45 ENSMUST00000003561.10
phytanoyl-CoA hydroxylase interacting protein
chr13_+_49761506 7.35 ENSMUST00000021822.7
osteoglycin
chr12_+_36042899 7.27 ENSMUST00000020898.12
anterior gradient 2
chr11_+_3438274 7.10 ENSMUST00000064265.13
phospholipase A2, group III
chr3_+_87855973 6.97 ENSMUST00000005019.6
cellular retinoic acid binding protein II
chr2_-_163239865 6.65 ENSMUST00000017961.11
ENSMUST00000109425.3
junctophilin 2
chr4_-_155095441 6.51 ENSMUST00000105631.9
ENSMUST00000139976.9
ENSMUST00000145662.9
phospholipase C, eta 2
chr16_+_78727829 6.40 ENSMUST00000114216.2
ENSMUST00000069148.13
ENSMUST00000023568.14
chondrolectin
chr11_-_83959175 6.39 ENSMUST00000100705.11
dual specificity phosphatase 14
chr11_+_98727611 6.23 ENSMUST00000107479.3
Rap guanine nucleotide exchange factor (GEF)-like 1
chr16_+_20513658 5.98 ENSMUST00000056518.13
family with sequence similarity 131, member A
chr19_+_24651362 5.95 ENSMUST00000057243.6
transmembrane protein 252
chr7_-_126651847 5.84 ENSMUST00000205424.2
zymogen granule protein 16
chr8_+_95498822 5.70 ENSMUST00000211956.2
ENSMUST00000211947.2
chemokine (C-X3-C motif) ligand 1
chr8_-_95405234 5.52 ENSMUST00000213043.2
plasma membrane proteolipid
chr1_-_128256048 5.50 ENSMUST00000073490.7
lactase
chr6_+_141470105 5.47 ENSMUST00000032362.12
ENSMUST00000205214.3
solute carrier organic anion transporter family, member 1c1
chr11_-_83959380 5.43 ENSMUST00000164891.8
dual specificity phosphatase 14
chr5_+_149335214 5.43 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr11_+_54205722 5.27 ENSMUST00000072178.11
ENSMUST00000101211.9
ENSMUST00000101213.9
ENSMUST00000064690.10
ENSMUST00000108899.8
acyl-CoA synthetase long-chain family member 6
chr15_-_78090591 5.27 ENSMUST00000120592.2
parvalbumin
chrX_+_10351360 5.18 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr10_-_89093441 5.17 ENSMUST00000182341.8
ENSMUST00000182613.8
anoctamin 4
chr7_+_26958150 4.97 ENSMUST00000079258.7
numb-like
chr10_+_57660948 4.95 ENSMUST00000020024.12
fatty acid binding protein 7, brain
chr12_-_72283465 4.85 ENSMUST00000021497.16
ENSMUST00000137990.2
reticulon 1
chr7_+_126396779 4.81 ENSMUST00000205324.2
TLC domain containing 3B
chr4_-_141351110 4.81 ENSMUST00000038661.8
solute carrier family 25, member 34
chr1_+_87522267 4.63 ENSMUST00000165109.2
ENSMUST00000070898.6
neuraminidase 2
chr9_+_22012357 4.63 ENSMUST00000216872.2
calponin 1
chr1_+_164624200 4.58 ENSMUST00000027861.6
dermatopontin
chr2_+_72128239 4.57 ENSMUST00000144111.2
mitogen-activated protein kinase kinase kinase 20
chr18_+_44096300 4.43 ENSMUST00000069245.8
serine peptidase inhibitor, Kazal type 5
chr14_-_118474404 4.39 ENSMUST00000170662.2
SRY (sex determining region Y)-box 21
chr1_+_171077984 4.34 ENSMUST00000111315.9
ENSMUST00000219033.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr16_+_41353212 4.27 ENSMUST00000078873.11
limbic system-associated membrane protein
chr11_+_96822213 4.26 ENSMUST00000107633.2
proline rich 15-like
chr11_+_68986043 4.25 ENSMUST00000101004.9
period circadian clock 1
chr15_-_37458768 4.24 ENSMUST00000116445.9
neurocalcin delta
chr15_-_101621332 4.23 ENSMUST00000023709.7
keratin 5
chr12_-_72455708 4.22 ENSMUST00000078505.14
reticulon 1
chr3_-_127202693 4.09 ENSMUST00000182078.9
ankyrin 2, brain
chr11_+_63019799 4.09 ENSMUST00000108702.8
peripheral myelin protein 22
chr13_+_43019718 4.07 ENSMUST00000131942.2
phosphatase and actin regulator 1
chr10_+_116013256 4.06 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr11_+_69047815 4.06 ENSMUST00000036424.3
arachidonate 12-lipoxygenase, 12R type
chr3_+_64884839 4.06 ENSMUST00000239069.2
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr8_+_31581635 4.06 ENSMUST00000161713.2
dual specificity phosphatase 26 (putative)
chr11_+_118878999 4.05 ENSMUST00000092373.13
ENSMUST00000106273.3
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr15_-_64794139 3.97 ENSMUST00000023007.7
ENSMUST00000228014.2
adenylate cyclase 8
chr14_-_55150547 3.89 ENSMUST00000228495.3
ENSMUST00000228119.3
ENSMUST00000050772.10
ENSMUST00000231305.2
solute carrier family 22 (organic cation transporter), member 17
chr8_-_120362291 3.88 ENSMUST00000061828.10
potassium voltage-gated channel, subfamily G, member 4
chr11_+_67090878 3.88 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr6_+_135339929 3.83 ENSMUST00000032330.16
epithelial membrane protein 1
chr2_+_35512023 3.83 ENSMUST00000091010.12
disabled 2 interacting protein
chr1_-_172047282 3.79 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr10_+_57661010 3.72 ENSMUST00000165013.2
fatty acid binding protein 7, brain
chr3_+_99203818 3.71 ENSMUST00000150756.3
T-box 15
chr18_-_20247824 3.70 ENSMUST00000038710.6
desmocollin 1
chr6_+_78347636 3.70 ENSMUST00000204873.3
regenerating islet-derived 3 beta
chr18_+_37840092 3.65 ENSMUST00000195823.2
protocadherin gamma subfamily A, 6
chr9_-_60418286 3.65 ENSMUST00000098660.10
thrombospondin, type I, domain containing 4
chr7_+_81984940 3.59 ENSMUST00000173287.8
ADAMTS-like 3
chr6_-_115228800 3.53 ENSMUST00000205131.2
tissue inhibitor of metalloproteinase 4
chr12_+_84408803 3.52 ENSMUST00000110278.8
ENSMUST00000145522.2
coenzyme Q6 monooxygenase
chr12_-_70394074 3.44 ENSMUST00000223160.2
ENSMUST00000222316.2
ENSMUST00000167755.3
ENSMUST00000110520.10
ENSMUST00000110522.10
ENSMUST00000221041.2
ENSMUST00000222603.3
tripartite motif-containing 9
chr18_-_23171713 3.42 ENSMUST00000081423.13
nucleolar protein 4
chr7_-_142223662 3.38 ENSMUST00000228850.2
predicted gene, 49394
chr1_+_66360865 3.37 ENSMUST00000114013.8
microtubule-associated protein 2
chr5_-_77262968 3.34 ENSMUST00000081964.7
HOP homeobox
chr2_-_113883285 3.33 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr13_-_113800172 3.32 ENSMUST00000054650.5
heat shock protein 3
chr6_-_24956296 3.31 ENSMUST00000127247.4
transmembrane protein 229A
chr13_-_32960379 3.31 ENSMUST00000230119.2
myosin light chain kinase family, member 4
chr2_-_25471703 3.30 ENSMUST00000114217.3
ENSMUST00000191602.2
apical junction component 1
chr6_-_124790029 3.28 ENSMUST00000149610.3
triosephosphate isomerase 1
chr5_-_137919873 3.24 ENSMUST00000031741.8
cytochrome P450, family 3, subfamily a, polypeptide 13
chr11_-_114686712 3.23 ENSMUST00000000206.4
BTB (POZ) domain containing 17
chr10_+_116013122 3.20 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr13_+_93440265 3.19 ENSMUST00000109494.8
homer scaffolding protein 1
chr6_+_78347844 3.17 ENSMUST00000096904.6
ENSMUST00000203266.2
regenerating islet-derived 3 beta
chr11_+_110914678 3.17 ENSMUST00000150902.8
ENSMUST00000178798.2
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_+_21095399 3.16 ENSMUST00000115458.9
phosphodiesterase 4A, cAMP specific
chr11_+_16207705 3.14 ENSMUST00000109645.9
ENSMUST00000109647.3
V-set and transmembrane domain containing 2A
chrX_-_58613428 3.13 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chr2_+_51928017 3.11 ENSMUST00000065927.6
tumor necrosis factor alpha induced protein 6
chr12_-_84408576 3.07 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr1_+_152275575 3.00 ENSMUST00000044311.9
collagen beta(1-O)galactosyltransferase 2
chr3_+_62245765 2.91 ENSMUST00000079300.13
Rho guanine nucleotide exchange factor (GEF) 26
chr12_-_45120895 2.90 ENSMUST00000120531.8
ENSMUST00000143376.8
syntaxin binding protein 6 (amisyn)
chr7_+_141276575 2.89 ENSMUST00000185406.8
mucin 2
chr1_+_133109059 2.88 ENSMUST00000187285.7
pleckstrin homology domain containing, family A member 6
chr11_-_102787950 2.85 ENSMUST00000067444.10
glial fibrillary acidic protein
chr2_+_22785534 2.82 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr11_-_102787972 2.81 ENSMUST00000077902.5
glial fibrillary acidic protein
chr7_+_27353331 2.79 ENSMUST00000008088.9
tetratricopeptide repeat domain 9B
chr3_-_127202635 2.79 ENSMUST00000182959.8
ankyrin 2, brain
chr13_+_120151982 2.78 ENSMUST00000179869.3
ENSMUST00000224188.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr18_-_20247928 2.76 ENSMUST00000226115.2
desmocollin 1
chr18_-_20247666 2.75 ENSMUST00000224432.2
desmocollin 1
chr6_+_135339543 2.75 ENSMUST00000205156.3
epithelial membrane protein 1
chr19_-_40576817 2.71 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
aldehyde dehydrogenase 18 family, member A1
chr12_+_84408742 2.71 ENSMUST00000021661.13
coenzyme Q6 monooxygenase
chr1_-_86039692 2.70 ENSMUST00000027431.7
5-hydroxytryptamine (serotonin) receptor 2B
chr1_+_159351337 2.66 ENSMUST00000192069.6
tenascin R
chr6_-_102441628 2.66 ENSMUST00000032159.7
contactin 3
chr13_+_42862957 2.65 ENSMUST00000066928.12
ENSMUST00000148891.8
phosphatase and actin regulator 1
chr15_+_10952418 2.63 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr13_+_120151915 2.59 ENSMUST00000225543.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr3_-_89186940 2.58 ENSMUST00000118860.2
ENSMUST00000029566.9
ephrin A1
chr11_+_115802828 2.57 ENSMUST00000132961.2
small integral membrane protein 6
chr8_-_65186565 2.56 ENSMUST00000141021.2
methylsterol monoxygenase 1
chr2_+_20742115 2.55 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr11_+_98274637 2.55 ENSMUST00000008021.3
titin-cap
chr2_-_24985161 2.54 ENSMUST00000044018.8
NADPH oxidase activator 1
chr3_+_107009896 2.54 ENSMUST00000196403.2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr1_+_169757498 2.53 ENSMUST00000175731.3
coiled-coil domain containing 190
chr7_+_44499374 2.52 ENSMUST00000141311.8
ENSMUST00000107880.9
ENSMUST00000208384.2
AKT1 substrate 1 (proline-rich)
chr3_+_123240562 2.50 ENSMUST00000029603.10
protease, serine 12 neurotrypsin (motopsin)
chr13_-_23806530 2.49 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr3_-_127202663 2.48 ENSMUST00000182008.8
ENSMUST00000182547.8
ankyrin 2, brain
chr2_+_22785593 2.47 ENSMUST00000152170.8
prenyl (solanesyl) diphosphate synthase, subunit 1
chr5_+_92535532 2.43 ENSMUST00000145072.8
ADP-ribosyltransferase 3
chrX_+_113384008 2.41 ENSMUST00000113371.8
ENSMUST00000040504.12
kelch-like 4
chr5_+_148202011 2.40 ENSMUST00000110515.9
microtubule associated tumor suppressor candidate 2
chr9_-_106324642 2.39 ENSMUST00000185334.7
ENSMUST00000187001.2
ENSMUST00000171678.9
ENSMUST00000190798.7
ENSMUST00000048685.13
ENSMUST00000171925.8
abhydrolase domain containing 14A
chrX_-_166638057 2.39 ENSMUST00000238211.2
FERM and PDZ domain containing 4
chrX_-_20816841 2.37 ENSMUST00000009550.14
ELK1, member of ETS oncogene family
chr3_+_76500857 2.34 ENSMUST00000162471.2
follistatin-like 5
chr9_+_89791943 2.33 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1
chr2_-_24985137 2.30 ENSMUST00000114373.8
NADPH oxidase activator 1
chr18_-_47466378 2.30 ENSMUST00000126684.2
ENSMUST00000156422.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr18_-_65527078 2.28 ENSMUST00000035548.16
alpha-kinase 2
chr5_-_31250817 2.27 ENSMUST00000031037.14
solute carrier family 30 (zinc transporter), member 3
chr19_+_8828132 2.25 ENSMUST00000235683.2
ENSMUST00000096257.3
LRRN4 C-terminal like
chrX_+_105230706 2.21 ENSMUST00000081593.13
phosphoglycerate kinase 1
chr7_+_19699291 2.20 ENSMUST00000094753.6
carcinoembryonic antigen-related cell adhesion molecule 20
chr10_+_21869776 2.18 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr11_+_78181667 2.18 ENSMUST00000046361.5
ENSMUST00000238934.2
ribosomal protein S6 kinase related
chr17_-_49871291 2.16 ENSMUST00000224595.2
ENSMUST00000057610.8
dishevelled associated activator of morphogenesis 2
chr3_-_108322868 2.16 ENSMUST00000090558.10
cadherin, EGF LAG seven-pass G-type receptor 2
chrX_+_103526380 2.15 ENSMUST00000087867.6
uracil phosphoribosyltransferase
chr19_-_40576897 2.13 ENSMUST00000025979.13
aldehyde dehydrogenase 18 family, member A1
chr5_+_92535705 2.12 ENSMUST00000138687.2
ENSMUST00000124509.2
ADP-ribosyltransferase 3
chr12_+_119354110 2.11 ENSMUST00000222058.2
metastasis associated in colon cancer 1
chr8_+_59364789 2.11 ENSMUST00000062978.7
cDNA sequence BC030500
chr5_-_84565218 2.09 ENSMUST00000113401.4
Eph receptor A5
chr13_+_83720457 2.09 ENSMUST00000196730.5
myocyte enhancer factor 2C
chr18_+_4994600 2.06 ENSMUST00000140448.8
supervillin
chr18_+_38088179 2.04 ENSMUST00000176902.8
ENSMUST00000176104.8
RELT-like 2
chr6_-_33037107 2.04 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr19_-_43512929 2.03 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chrX_-_105647282 2.02 ENSMUST00000113480.2
cysteinyl leukotriene receptor 1
chr7_-_19621833 1.97 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr6_-_136852792 1.96 ENSMUST00000032342.3
matrix Gla protein
chrX_+_149829131 1.93 ENSMUST00000112685.8
FYVE, RhoGEF and PH domain containing 1
chr9_+_121196034 1.93 ENSMUST00000210636.2
ENSMUST00000045903.8
trafficking protein, kinesin binding 1
chr11_+_50917831 1.93 ENSMUST00000072152.2
olfactory receptor 54
chr2_+_133394079 1.91 ENSMUST00000028836.7
bone morphogenetic protein 2
chr11_+_67128843 1.87 ENSMUST00000018632.11
myosin, heavy polypeptide 4, skeletal muscle
chr19_-_40576782 1.85 ENSMUST00000176939.8
aldehyde dehydrogenase 18 family, member A1
chr8_-_120362085 1.83 ENSMUST00000164382.2
potassium voltage-gated channel, subfamily G, member 4
chr3_-_127202586 1.82 ENSMUST00000183095.3
ENSMUST00000182610.8
ankyrin 2, brain
chr3_+_128993568 1.82 ENSMUST00000029657.16
ENSMUST00000106382.11
paired-like homeodomain transcription factor 2
chr2_+_3115250 1.81 ENSMUST00000072955.12
family with sequence similarity 171, member A1
chr7_+_120442048 1.79 ENSMUST00000047875.16
eukaryotic elongation factor-2 kinase
chr18_-_43032359 1.78 ENSMUST00000117687.8
protein phosphatase 2, regulatory subunit B, beta
chr7_+_44498640 1.73 ENSMUST00000054343.15
ENSMUST00000142880.3
AKT1 substrate 1 (proline-rich)
chr13_+_83720484 1.72 ENSMUST00000196207.5
myocyte enhancer factor 2C
chr19_-_40600619 1.72 ENSMUST00000132452.2
ENSMUST00000135795.8
ENSMUST00000025981.15
tectonic family member 3
chr11_+_67689094 1.71 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr14_-_36628263 1.70 ENSMUST00000183007.2
coiled-coil serine rich 2
chr1_+_74583504 1.66 ENSMUST00000027362.14
phospholipase C, delta 4
chr9_+_43978369 1.66 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chr12_-_91712783 1.62 ENSMUST00000166967.2
stonin 2
chr19_+_56276343 1.62 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr4_+_102287244 1.60 ENSMUST00000172616.2
phosphodiesterase 4B, cAMP specific
chr4_-_129155185 1.57 ENSMUST00000145261.8
expressed sequence C77080
chr18_+_69633741 1.56 ENSMUST00000207214.2
ENSMUST00000201094.4
ENSMUST00000200703.4
ENSMUST00000202765.4
transcription factor 4
chr17_-_36012932 1.55 ENSMUST00000166980.9
ENSMUST00000145900.8
discoidin domain receptor family, member 1
chr2_-_5680801 1.54 ENSMUST00000114987.4
calcium/calmodulin-dependent protein kinase ID
chr5_-_123887434 1.53 ENSMUST00000182955.8
ENSMUST00000182489.8
ENSMUST00000183147.9
ENSMUST00000050827.14
ENSMUST00000057795.12
ENSMUST00000111515.8
ENSMUST00000182309.8
arginine/serine-rich coiled-coil 2
chr16_+_20492014 1.50 ENSMUST00000154950.8
ENSMUST00000115461.8
ENSMUST00000136713.5
eukaryotic translation initiation factor 4, gamma 1
chr8_-_68658694 1.47 ENSMUST00000212960.2
pleckstrin and Sec7 domain containing 3
chr3_+_89987749 1.46 ENSMUST00000127955.2
tropomyosin 3, gamma
chr13_+_25127127 1.45 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr1_+_90131702 1.45 ENSMUST00000065587.5
ENSMUST00000159654.2
atypical chemokine receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
3.2 9.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
2.4 7.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
2.2 6.7 GO:0006592 ornithine biosynthetic process(GO:0006592)
2.1 8.5 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.4 7.0 GO:0010040 response to iron(II) ion(GO:0010040)
1.3 10.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
1.2 8.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.2 11.2 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 7.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.1 3.4 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
1.1 5.7 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.1 6.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.1 3.3 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.1 5.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
1.1 9.5 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.9 3.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 5.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 5.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.8 4.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.8 4.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.8 3.8 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.7 4.4 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.7 5.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.7 4.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.7 2.0 GO:0006533 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.7 2.7 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.6 3.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.6 3.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6 7.5 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.6 2.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.6 4.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.6 5.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.5 5.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 12.2 GO:0030953 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.5 4.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.5 11.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.5 1.9 GO:0003130 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.5 6.2 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.5 12.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 2.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.4 2.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) notochord formation(GO:0014028)
0.4 2.5 GO:0021633 optic nerve structural organization(GO:0021633)
0.4 4.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 7.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 7.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.4 10.7 GO:0032060 bleb assembly(GO:0032060)
0.4 1.9 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.4 5.0 GO:0021873 forebrain neuroblast division(GO:0021873)
0.4 2.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 2.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.3 8.7 GO:0060134 prepulse inhibition(GO:0060134)
0.3 2.6 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.3 2.3 GO:0097501 stress response to metal ion(GO:0097501)
0.3 3.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 6.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.3 3.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 1.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 2.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.3 2.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.3 3.4 GO:0042407 cristae formation(GO:0042407)
0.3 0.8 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 11.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.8 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.2 4.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 0.9 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.2 2.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 2.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 3.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 4.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 5.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 0.8 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 4.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 2.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 3.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.9 GO:0002003 angiotensin maturation(GO:0002003)
0.1 2.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 5.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793) response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 5.1 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 8.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 4.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.9 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 1.3 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 0.3 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 2.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 1.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 4.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 4.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 1.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.1 0.6 GO:0031296 B cell costimulation(GO:0031296)
0.1 2.1 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.1 0.2 GO:0046436 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.1 GO:2000729 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.1 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 2.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 9.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 5.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.9 GO:0014823 response to activity(GO:0014823)
0.1 1.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 2.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.5 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 3.7 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 5.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 2.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 5.6 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 2.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353) negative regulation of centriole replication(GO:0046600)
0.0 6.6 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 2.2 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 1.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0060290 transdifferentiation(GO:0060290)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 3.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.8 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 3.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.5 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 2.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 2.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 4.8 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.3 GO:0060349 bone morphogenesis(GO:0060349)
0.0 1.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 2.1 GO:0007519 skeletal muscle tissue development(GO:0007519)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.2 26.5 GO:0042589 zymogen granule membrane(GO:0042589)
1.1 10.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.1 3.3 GO:0042643 actomyosin, actin portion(GO:0042643)
1.0 3.8 GO:0070722 Tle3-Aes complex(GO:0070722)
1.0 3.8 GO:1990032 parallel fiber(GO:1990032)
0.9 4.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.7 6.7 GO:0030314 junctional membrane complex(GO:0030314)
0.7 5.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.7 2.7 GO:0072534 perineuronal net(GO:0072534)
0.6 1.7 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.4 6.9 GO:0042588 zymogen granule(GO:0042588)
0.4 3.4 GO:0061617 MICOS complex(GO:0061617)
0.4 4.2 GO:0031931 TORC1 complex(GO:0031931)
0.4 3.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 15.5 GO:0045095 keratin filament(GO:0045095)
0.3 8.7 GO:0071564 npBAF complex(GO:0071564)
0.3 1.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 7.6 GO:0046930 pore complex(GO:0046930)
0.3 9.6 GO:0043218 compact myelin(GO:0043218)
0.3 16.4 GO:0043034 costamere(GO:0043034)
0.3 9.2 GO:0030057 desmosome(GO:0030057)
0.3 4.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 3.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 8.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 5.5 GO:0032982 myosin filament(GO:0032982)
0.2 5.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 0.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 2.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 2.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.9 GO:0000145 exocyst(GO:0000145)
0.1 10.1 GO:0014704 intercalated disc(GO:0014704)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.9 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 13.2 GO:0030017 sarcomere(GO:0030017)
0.1 7.1 GO:0005814 centriole(GO:0005814)
0.1 5.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 5.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 17.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 6.6 GO:0043679 axon terminus(GO:0043679)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 2.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.8 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 9.0 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.6 GO:0005903 brush border(GO:0005903)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 69.5 GO:0005829 cytosol(GO:0005829)
0.0 1.6 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0035375 zymogen binding(GO:0035375)
3.2 9.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
2.2 6.7 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
2.1 10.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.8 5.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.3 5.3 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
1.1 2.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.1 9.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.0 15.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
1.0 2.9 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.9 4.6 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.9 5.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.8 7.6 GO:0015288 porin activity(GO:0015288)
0.7 11.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 5.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.7 2.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.7 4.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.6 4.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.5 2.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 2.5 GO:0051373 FATZ binding(GO:0051373)
0.5 3.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 10.6 GO:0002162 dystroglycan binding(GO:0002162)
0.4 13.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 4.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 2.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 7.0 GO:0019841 retinol binding(GO:0019841)
0.4 4.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 5.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 9.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 6.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 3.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 4.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 8.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 0.9 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 1.5 GO:0070287 ferritin receptor activity(GO:0070287)
0.3 7.5 GO:0003680 AT DNA binding(GO:0003680)
0.3 2.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 8.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 5.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 8.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 3.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2 0.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.9 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 8.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.9 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.2 2.7 GO:0051378 serotonin binding(GO:0051378)
0.2 8.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 6.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.5 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.2 6.4 GO:0071949 FAD binding(GO:0071949)
0.2 4.1 GO:0070402 NADPH binding(GO:0070402)
0.2 1.5 GO:0004630 phospholipase D activity(GO:0004630)
0.2 3.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.7 GO:0046625 sphingolipid binding(GO:0046625)
0.1 5.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.0 GO:0050815 phosphoserine binding(GO:0050815)
0.1 5.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 11.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 4.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 3.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 4.3 GO:0070888 E-box binding(GO:0070888)
0.1 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 4.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0043426 MRF binding(GO:0043426) RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 8.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 11.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 3.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 10.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 3.4 GO:0000149 SNARE binding(GO:0000149)
0.0 3.2 GO:0005550 pheromone binding(GO:0005550)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 13.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 1.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 7.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 14.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 4.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 15.0 PID LKB1 PATHWAY LKB1 signaling events
0.2 7.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 7.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 7.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 5.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 9.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 18.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.9 PID BMP PATHWAY BMP receptor signaling
0.0 6.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.7 16.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.5 6.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.5 26.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 9.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 5.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 6.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 4.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 2.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 9.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 4.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 9.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 11.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 12.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 5.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 4.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 7.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.4 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.8 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins