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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nfkb2

Z-value: 1.06

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Transcription factors associated with Nfkb2

Gene Symbol Gene ID Gene Info
Nfkb2
ENSMUSG00000025225.16 Nfkb2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfkb2mm39_v1_chr19_+_46293210_462932500.692.4e-11Click!

Activity profile of Nfkb2 motif

Sorted Z-values of Nfkb2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfkb2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_43938251 18.07 ENSMUST00000015540.4
Cd83
CD83 antigen
chr7_-_44181477 12.50 ENSMUST00000098483.9
ENSMUST00000035323.6
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr17_-_35424281 6.93 ENSMUST00000025266.6
Lta
lymphotoxin A
chr19_+_46293210 6.56 ENSMUST00000236591.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr17_+_56259617 6.08 ENSMUST00000003274.8
Ebi3
Epstein-Barr virus induced gene 3
chr19_+_6391148 6.01 ENSMUST00000025897.13
ENSMUST00000130382.8
Map4k2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_+_70548022 5.32 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
Eno3
enolase 3, beta muscle
chr7_+_30121776 5.18 ENSMUST00000108175.8
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chrX_-_7537580 5.11 ENSMUST00000033486.6
Plp2
proteolipid protein 2
chr8_-_105357941 5.06 ENSMUST00000034351.8
Rrad
Ras-related associated with diabetes
chr19_+_46293160 5.02 ENSMUST00000073116.13
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr7_-_19363280 4.90 ENSMUST00000094762.10
ENSMUST00000049912.15
ENSMUST00000098754.5
Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr7_+_30121147 4.30 ENSMUST00000108176.9
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr4_-_125021610 4.13 ENSMUST00000036188.8
Zc3h12a
zinc finger CCCH type containing 12A
chr11_+_70548622 4.12 ENSMUST00000170716.8
Eno3
enolase 3, beta muscle
chr11_-_54853729 3.95 ENSMUST00000108885.8
ENSMUST00000102730.9
ENSMUST00000018482.13
ENSMUST00000108886.8
ENSMUST00000102731.8
Tnip1
TNFAIP3 interacting protein 1
chr19_+_46292759 3.75 ENSMUST00000237330.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr17_+_35598583 3.62 ENSMUST00000081435.5
H2-Q4
histocompatibility 2, Q region locus 4
chr3_+_97565528 3.49 ENSMUST00000045743.13
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr9_+_5308828 3.48 ENSMUST00000162846.8
ENSMUST00000027012.14
Casp4
caspase 4, apoptosis-related cysteine peptidase
chr17_+_35643818 3.38 ENSMUST00000174699.8
H2-Q6
histocompatibility 2, Q region locus 6
chr11_+_70548513 3.16 ENSMUST00000134087.8
Eno3
enolase 3, beta muscle
chr14_+_80237691 3.07 ENSMUST00000228749.2
ENSMUST00000088735.4
Olfm4
olfactomedin 4
chr8_-_105357872 3.05 ENSMUST00000212163.2
Rrad
Ras-related associated with diabetes
chr7_+_67925718 3.03 ENSMUST00000210558.2
Fam169b
family with sequence similarity 169, member B
chr14_-_30329765 2.91 ENSMUST00000112207.8
ENSMUST00000112206.8
ENSMUST00000112202.8
ENSMUST00000112203.2
Prkcd
protein kinase C, delta
chr14_-_30348153 2.82 ENSMUST00000112211.9
ENSMUST00000112210.11
Prkcd
protein kinase C, delta
chr11_-_23720953 2.82 ENSMUST00000102864.5
Rel
reticuloendotheliosis oncogene
chr17_+_35643853 2.45 ENSMUST00000113879.4
H2-Q6
histocompatibility 2, Q region locus 6
chr6_+_68547717 2.43 ENSMUST00000196839.5
ENSMUST00000103327.3
Igkv12-98
immunoglobulin kappa variable 12-98
chr19_+_53517528 2.42 ENSMUST00000038287.7
Dusp5
dual specificity phosphatase 5
chr11_+_77576981 2.16 ENSMUST00000100802.11
ENSMUST00000181023.2
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr11_+_69920542 1.99 ENSMUST00000232266.2
ENSMUST00000132597.5
Dlg4
discs large MAGUK scaffold protein 4
chrX_+_162692126 1.77 ENSMUST00000033734.14
ENSMUST00000112294.9
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr5_+_90907207 1.60 ENSMUST00000031318.6
Cxcl5
chemokine (C-X-C motif) ligand 5
chr7_-_100951227 1.59 ENSMUST00000122116.8
ENSMUST00000120267.9
Atg16l2
autophagy related 16-like 2 (S. cerevisiae)
chr7_+_16043502 1.57 ENSMUST00000002152.13
Bbc3
BCL2 binding component 3
chr2_-_3420056 1.56 ENSMUST00000115084.8
ENSMUST00000115083.8
Meig1
meiosis expressed gene 1
chr4_+_151012375 1.52 ENSMUST00000139826.8
ENSMUST00000116257.8
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr1_-_63153414 1.48 ENSMUST00000153992.2
ENSMUST00000165066.8
ENSMUST00000172416.8
ENSMUST00000137511.8
Ino80d
INO80 complex subunit D
chr15_-_102154874 1.43 ENSMUST00000063339.14
Rarg
retinoic acid receptor, gamma
chr1_-_63153675 1.42 ENSMUST00000097718.9
Ino80d
INO80 complex subunit D
chr2_-_93292257 1.38 ENSMUST00000150508.8
Cd82
CD82 antigen
chr2_-_3420102 1.30 ENSMUST00000115082.10
Meig1
meiosis expressed gene 1
chr17_-_88372315 1.28 ENSMUST00000235056.2
ENSMUST00000130379.9
Fbxo11
F-box protein 11
chr7_-_44702269 1.27 ENSMUST00000057293.8
Prr12
proline rich 12
chr3_-_116217579 1.26 ENSMUST00000106491.7
ENSMUST00000090464.7
Cdc14a
CDC14 cell division cycle 14A
chr1_-_36982747 1.24 ENSMUST00000185964.3
Tmem131
transmembrane protein 131
chr8_+_79755194 1.24 ENSMUST00000119254.8
ENSMUST00000238669.2
Zfp827
zinc finger protein 827
chr2_-_37312881 1.21 ENSMUST00000112936.4
ENSMUST00000112934.8
Rc3h2
ring finger and CCCH-type zinc finger domains 2
chrX_+_162691978 1.21 ENSMUST00000069041.15
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr9_-_106762818 1.17 ENSMUST00000185707.2
Rbm15b
RNA binding motif protein 15B
chr6_-_69920632 1.09 ENSMUST00000198880.5
ENSMUST00000103371.3
Igkv12-38
immunoglobulin kappa chain variable 12-38
chr3_+_31149201 1.05 ENSMUST00000118470.8
ENSMUST00000029194.12
ENSMUST00000123532.2
Skil
SKI-like
chr8_+_120729459 0.98 ENSMUST00000108972.4
Crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr1_+_132996237 0.85 ENSMUST00000239467.2
Pik3c2b
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr19_-_46327024 0.84 ENSMUST00000236046.2
ENSMUST00000236980.2
ENSMUST00000235485.2
ENSMUST00000236061.2
ENSMUST00000236236.2
ENSMUST00000236768.2
ENSMUST00000236651.2
Cuedc2
CUE domain containing 2
chr19_-_46327071 0.81 ENSMUST00000235977.2
ENSMUST00000167861.8
ENSMUST00000051234.9
ENSMUST00000236066.2
Cuedc2
CUE domain containing 2
chr2_-_120144622 0.76 ENSMUST00000054651.8
Pla2g4f
phospholipase A2, group IVF
chr17_-_36291087 0.75 ENSMUST00000055454.14
Prr3
proline-rich polypeptide 3
chr5_+_91051722 0.69 ENSMUST00000200681.4
ENSMUST00000075433.8
Cxcl2
chemokine (C-X-C motif) ligand 2
chr5_-_137529251 0.69 ENSMUST00000132525.8
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr8_+_124138163 0.68 ENSMUST00000071134.4
ENSMUST00000212743.2
Tubb3
tubulin, beta 3 class III
chr3_+_31149247 0.65 ENSMUST00000117728.8
Skil
SKI-like
chr10_+_127257077 0.63 ENSMUST00000168780.8
R3hdm2
R3H domain containing 2
chr1_+_74830675 0.62 ENSMUST00000006718.15
Wnt10a
wingless-type MMTV integration site family, member 10A
chr17_+_36290743 0.60 ENSMUST00000087200.4
Gnl1
guanine nucleotide binding protein-like 1
chr7_-_125799570 0.60 ENSMUST00000009344.16
Xpo6
exportin 6
chr7_-_125799644 0.59 ENSMUST00000168189.8
Xpo6
exportin 6
chr10_+_80538482 0.56 ENSMUST00000095426.5
Izumo4
IZUMO family member 4
chr7_+_28988724 0.54 ENSMUST00000207714.2
ENSMUST00000048187.6
Ppp1r14a
protein phosphatase 1, regulatory inhibitor subunit 14A
chr1_+_34840785 0.52 ENSMUST00000047664.16
ENSMUST00000211073.2
Arhgef4
SMIM39
Rho guanine nucleotide exchange factor (GEF) 4
novel protein
chr13_-_111626562 0.49 ENSMUST00000091236.11
ENSMUST00000047627.14
Gpbp1
GC-rich promoter binding protein 1
chr8_+_79754980 0.47 ENSMUST00000087927.11
ENSMUST00000098614.9
Zfp827
zinc finger protein 827
chr4_+_124880223 0.46 ENSMUST00000030687.8
Rspo1
R-spondin 1
chr5_-_137529465 0.42 ENSMUST00000150063.9
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr11_-_84761637 0.39 ENSMUST00000168434.8
Ggnbp2
gametogenetin binding protein 2
chr2_-_164315634 0.33 ENSMUST00000017864.3
Trp53tg5
transformation related protein 53 target 5
chr4_+_140815644 0.29 ENSMUST00000051907.3
Spata21
spermatogenesis associated 21
chr7_+_18910340 0.28 ENSMUST00000117338.8
Eml2
echinoderm microtubule associated protein like 2
chr8_-_106015682 0.26 ENSMUST00000212922.2
ENSMUST00000212219.2
4931428F04Rik
RIKEN cDNA 4931428F04 gene
chr8_-_106016097 0.23 ENSMUST00000171788.8
4931428F04Rik
RIKEN cDNA 4931428F04 gene
chr11_-_84761538 0.21 ENSMUST00000170741.2
ENSMUST00000172405.8
ENSMUST00000100686.10
ENSMUST00000108081.9
Ggnbp2
gametogenetin binding protein 2
chr11_-_71928300 0.20 ENSMUST00000048207.10
Aipl1
aryl hydrocarbon receptor-interacting protein-like 1
chr11_-_84761472 0.18 ENSMUST00000018547.9
Ggnbp2
gametogenetin binding protein 2
chr6_-_83433357 0.15 ENSMUST00000186548.7
Tet3
tet methylcytosine dioxygenase 3
chr1_-_152778373 0.07 ENSMUST00000073441.13
ENSMUST00000111836.4
Smg7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr1_+_149975782 0.05 ENSMUST00000035065.9
Ptgs2
prostaglandin-endoperoxide synthase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.3 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
2.3 6.9 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
1.8 18.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
1.4 5.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
1.4 8.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.9 11.0 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.9 8.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.5 3.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.3 2.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 1.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 1.7 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.6 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 11.9 GO:0030225 macrophage differentiation(GO:0030225)
0.2 4.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.6 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 1.5 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.2 6.0 GO:0006903 vesicle targeting(GO:0006903)
0.2 9.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2 2.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.0 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 12.6 GO:0006096 glycolytic process(GO:0006096)
0.0 3.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 3.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.8 GO:0071236 cellular response to antibiotic(GO:0071236)
0.0 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 6.1 GO:0042098 T cell proliferation(GO:0042098)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 3.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 2.9 GO:0006310 DNA recombination(GO:0006310)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
1.0 7.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.9 12.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.9 3.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.7 9.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.6 4.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 3.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.1 GO:0042581 specific granule(GO:0042581)
0.1 2.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 5.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 19.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 11.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.9 12.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 9.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 6.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 3.5 GO:0050700 CARD domain binding(GO:0050700)
0.3 2.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 4.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 15.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 9.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 5.1 GO:0019956 chemokine binding(GO:0019956)
0.1 3.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 6.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 4.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0001727 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 6.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 17.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 4.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 10.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 6.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 5.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 6.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 8.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.0 ST GA12 PATHWAY G alpha 12 Pathway
0.1 3.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.6 PID P73PATHWAY p73 transcription factor network
0.0 1.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 12.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 5.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway