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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx1-1_Nkx1-2

Z-value: 0.66

Motif logo

Transcription factors associated with Nkx1-1_Nkx1-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000029112.6 Nkx1-1
ENSMUSG00000048528.8 Nkx1-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx1-1mm39_v1_chr5_-_33591320_335913200.352.4e-03Click!
Nkx1-2mm39_v1_chr7_-_132201344_1322013660.028.8e-01Click!

Activity profile of Nkx1-1_Nkx1-2 motif

Sorted Z-values of Nkx1-1_Nkx1-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx1-1_Nkx1-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_22965286 6.63 ENSMUST00000023593.6
adiponectin, C1Q and collagen domain containing
chr16_+_22965330 5.42 ENSMUST00000171309.2
adiponectin, C1Q and collagen domain containing
chr6_-_124756645 4.01 ENSMUST00000147669.2
ENSMUST00000128697.8
ENSMUST00000032218.10
ENSMUST00000112475.9
leucine rich repeat containing 23
chr1_-_171854818 3.82 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr14_-_70666513 3.80 ENSMUST00000226426.2
ENSMUST00000048129.6
piwi-like RNA-mediated gene silencing 2
chr11_+_87000032 3.46 ENSMUST00000020794.6
spindle and kinetochore associated complex subunit 2
chr18_+_12874390 3.00 ENSMUST00000121018.8
ENSMUST00000119108.8
ENSMUST00000186263.2
ENSMUST00000191078.7
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr19_+_8779903 2.97 ENSMUST00000172175.3
zinc finger and BTB domain containing 3
chr8_-_3744167 2.75 ENSMUST00000005678.6
Fc receptor, IgE, low affinity II, alpha polypeptide
chr11_-_86999481 2.27 ENSMUST00000051395.9
proline rich 11
chr3_-_90297187 2.15 ENSMUST00000029541.12
solute carrier family 27 (fatty acid transporter), member 3
chr3_+_94320548 1.99 ENSMUST00000166032.8
ENSMUST00000200486.5
ENSMUST00000196386.5
ENSMUST00000045245.10
ENSMUST00000197901.5
ENSMUST00000198041.2
tudor and KH domain containing protein
predicted gene 42463
chr18_+_12874368 1.95 ENSMUST00000235000.2
ENSMUST00000115857.9
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr14_+_65612788 1.93 ENSMUST00000224687.2
zinc finger protein 395
chr11_+_104468107 1.83 ENSMUST00000106956.10
myosin, light polypeptide 4
chr7_-_24423715 1.83 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr11_+_104467791 1.78 ENSMUST00000106957.8
myosin, light polypeptide 4
chr4_-_140501507 1.78 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr18_-_24736848 1.70 ENSMUST00000070726.10
solute carrier family 39 (metal ion transporter), member 6
chr5_-_82272549 1.70 ENSMUST00000188072.2
ENSMUST00000185410.2
RIKEN cDNA 1700031L13 gene
chr1_-_144427302 1.70 ENSMUST00000184189.3
regulator of G-protein signalling 21
chr6_+_29694181 1.70 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr16_+_51851588 1.65 ENSMUST00000114471.3
Casitas B-lineage lymphoma b
chr15_+_97990431 1.63 ENSMUST00000229280.2
ENSMUST00000163507.8
ENSMUST00000230445.2
phosphofructokinase, muscle
chr3_-_15902583 1.59 ENSMUST00000108354.8
ENSMUST00000108349.2
ENSMUST00000108352.9
ENSMUST00000108350.8
ENSMUST00000050623.11
signal-regulatory protein beta 1C
chr5_+_138115165 1.53 ENSMUST00000062350.15
ENSMUST00000110961.9
ENSMUST00000080732.10
ENSMUST00000110960.9
ENSMUST00000142185.8
ENSMUST00000136425.2
ENSMUST00000110959.2
zinc finger and SCAN domain containing 21
chr4_-_88595161 1.34 ENSMUST00000105148.2
interferon alpha 16
chr18_-_24736521 1.31 ENSMUST00000154205.2
solute carrier family 39 (metal ion transporter), member 6
chr2_+_154390808 1.30 ENSMUST00000045116.11
ENSMUST00000109709.4
RIKEN cDNA 1700003F12 gene
chr9_-_20871081 1.29 ENSMUST00000177754.9
DNA methyltransferase (cytosine-5) 1
chr11_+_116734104 1.26 ENSMUST00000106370.10
methyltransferase like 23
chr19_-_40371016 1.26 ENSMUST00000225766.3
sorbin and SH3 domain containing 1
chr3_-_116217579 1.24 ENSMUST00000106491.7
ENSMUST00000090464.7
CDC14 cell division cycle 14A
chr17_+_7437500 1.20 ENSMUST00000024575.8
ribosomal protein S6 kinase, polypeptide 2
chr6_+_145561483 1.20 ENSMUST00000087445.7
tubulin, alpha 3B
chr15_-_79626719 1.13 ENSMUST00000089311.11
ENSMUST00000046259.14
Sad1 and UNC84 domain containing 2
chr1_-_150341911 1.10 ENSMUST00000162367.8
ENSMUST00000161611.8
ENSMUST00000161320.8
ENSMUST00000159035.2
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr7_-_30251680 1.10 ENSMUST00000215288.2
ENSMUST00000108165.8
ENSMUST00000153594.3
proline and serine rich 3
chr15_-_79626694 1.09 ENSMUST00000100439.10
Sad1 and UNC84 domain containing 2
chr4_-_14621805 1.04 ENSMUST00000042221.14
solute carrier family 26, member 7
chr6_-_23650297 1.03 ENSMUST00000063548.4
ring finger protein 133
chr1_-_131441962 1.02 ENSMUST00000185445.3
SLIT-ROBO Rho GTPase activating protein 2
chr2_+_91095597 1.01 ENSMUST00000028691.7
ADP-ribosylation factor GTPase activating protein 2
chr4_-_14621497 1.00 ENSMUST00000149633.2
solute carrier family 26, member 7
chr14_+_46997984 0.99 ENSMUST00000067426.6
cyclin-dependent kinase inhibitor 3
chr12_+_4819277 0.96 ENSMUST00000020967.11
profilin family, member 4
chr14_-_70666821 0.94 ENSMUST00000226229.2
piwi-like RNA-mediated gene silencing 2
chr12_+_4819339 0.93 ENSMUST00000178879.3
profilin family, member 4
chrX_+_159551009 0.92 ENSMUST00000033650.14
retinoschisis (X-linked, juvenile) 1 (human)
chr6_-_23650205 0.91 ENSMUST00000115354.2
ring finger protein 133
chr5_-_137101108 0.91 ENSMUST00000077523.4
ENSMUST00000041388.11
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr8_-_87307294 0.90 ENSMUST00000131423.8
ENSMUST00000152438.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr4_-_131802606 0.90 ENSMUST00000146021.8
erythrocyte membrane protein band 4.1
chr9_-_26717686 0.90 ENSMUST00000162702.8
ENSMUST00000040398.14
ENSMUST00000066560.13
galactosidase, beta 1-like 2
chr2_-_45002902 0.89 ENSMUST00000076836.13
ENSMUST00000176732.8
ENSMUST00000200844.4
zinc finger E-box binding homeobox 2
chr4_-_43710231 0.88 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr12_+_108145802 0.83 ENSMUST00000221167.2
cyclin K
chr4_-_14621669 0.82 ENSMUST00000143105.2
solute carrier family 26, member 7
chr6_-_128339775 0.80 ENSMUST00000112152.8
ENSMUST00000057421.15
ENSMUST00000112151.2
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr15_-_77840856 0.80 ENSMUST00000117725.2
ENSMUST00000016696.13
FAD-dependent oxidoreductase domain containing 2
chr12_+_4819022 0.80 ENSMUST00000219503.2
profilin family, member 4
chr12_-_4819216 0.77 ENSMUST00000053458.7
ENSMUST00000218575.2
family with sequence similarity 228, member B
chr1_+_54289833 0.77 ENSMUST00000027128.11
coiled-coil domain containing 150
chr12_+_4819151 0.76 ENSMUST00000219438.2
profilin family, member 4
chr12_-_40087393 0.76 ENSMUST00000146905.2
ADP-ribosylation factor-like 4A
chr6_-_128339458 0.75 ENSMUST00000155573.3
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr4_-_131802561 0.75 ENSMUST00000105970.8
ENSMUST00000105975.8
erythrocyte membrane protein band 4.1
chr2_-_160950936 0.73 ENSMUST00000039782.14
ENSMUST00000134178.8
chromodomain helicase DNA binding protein 6
chr2_+_68490186 0.71 ENSMUST00000055930.6
RIKEN cDNA 4932414N04 gene
chr15_+_41694317 0.70 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr19_+_29344846 0.70 ENSMUST00000016640.8
CD274 antigen
chr7_+_101545547 0.69 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr7_-_12829100 0.69 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr5_-_122959361 0.66 ENSMUST00000086216.9
anaphase-promoting complex subunit 5
chr11_-_99134885 0.64 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr9_+_40092216 0.63 ENSMUST00000218134.2
ENSMUST00000216720.2
ENSMUST00000214763.2
olfactory receptor 986
chr7_+_140181182 0.62 ENSMUST00000214180.2
ENSMUST00000211771.2
olfactory receptor 46
chr3_+_121746862 0.61 ENSMUST00000037958.14
ENSMUST00000196904.5
Rho GTPase activating protein 29
chr2_-_27365633 0.60 ENSMUST00000138693.8
ENSMUST00000113941.9
ENSMUST00000077737.13
bromodomain containing 3
chr9_-_44024767 0.58 ENSMUST00000216511.2
ENSMUST00000056328.6
ENSMUST00000185479.2
ring finger protein 26
predicted gene, 49380
chr19_-_41921676 0.57 ENSMUST00000075280.12
ENSMUST00000112123.4
exosome component 1
chr4_-_112632013 0.56 ENSMUST00000060327.4
selection and upkeep of intraepithelial T cells 10
chrX_+_56257374 0.55 ENSMUST00000033466.2
CD40 ligand
chr9_-_100368841 0.55 ENSMUST00000098458.4
interleukin 20 receptor beta
chr15_+_16728842 0.55 ENSMUST00000228307.2
cadherin 9
chr7_-_110673269 0.54 ENSMUST00000163014.2
eukaryotic translation initiation factor 4, gamma 2
chr5_+_30824121 0.54 ENSMUST00000144742.6
ENSMUST00000149759.2
ENSMUST00000199320.5
centromere protein A
chr19_+_60744385 0.54 ENSMUST00000088237.6
nanos C2HC-type zinc finger 1
chr14_+_46998004 0.52 ENSMUST00000227149.2
cyclin-dependent kinase inhibitor 3
chr17_-_57338468 0.52 ENSMUST00000007814.10
ENSMUST00000233480.2
KH-type splicing regulatory protein
chr11_+_43572825 0.52 ENSMUST00000061070.6
ENSMUST00000094294.5
PWWP domain containing 2A
chr10_+_97442727 0.48 ENSMUST00000105286.4
keratocan
chr2_-_111843053 0.46 ENSMUST00000213559.3
olfactory receptor 1310
chr12_+_84463970 0.45 ENSMUST00000183146.2
ring finger protein 113A2
chrX_-_73129195 0.45 ENSMUST00000140399.3
ENSMUST00000123362.8
ENSMUST00000100750.10
ENSMUST00000033770.13
methyl CpG binding protein 2
chr14_-_59602882 0.45 ENSMUST00000160425.8
ENSMUST00000095157.11
PHD finger protein 11D
chr9_-_97252011 0.45 ENSMUST00000035026.5
tripartite motif-containing 42
chr11_-_43638790 0.44 ENSMUST00000048578.3
ENSMUST00000109278.8
tetratricopeptide repeat domain 1
chr5_+_143846782 0.43 ENSMUST00000148011.8
ENSMUST00000110709.7
PMS1 homolog2, mismatch repair system component
chr6_-_57512355 0.43 ENSMUST00000042766.6
protein phosphatase 1K (PP2C domain containing)
chr11_-_99121822 0.42 ENSMUST00000103133.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr1_+_174329361 0.42 ENSMUST00000030039.13
formin 2
chr2_-_102230602 0.41 ENSMUST00000152929.2
tripartite motif-containing 44
chr3_+_75982890 0.40 ENSMUST00000160261.8
follistatin-like 5
chr2_+_89642395 0.39 ENSMUST00000214508.2
olfactory receptor 1255
chr6_-_8180174 0.39 ENSMUST00000213284.2
collagen, type XXVIII, alpha 1
chr11_-_97040858 0.38 ENSMUST00000118375.8
TBK1 binding protein 1
chr13_-_103042554 0.36 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chrX_-_8391193 0.36 ENSMUST00000115573.2
predicted gene 14459
chr15_+_75865604 0.35 ENSMUST00000089669.6
mitogen-activated protein kinase 15
chr14_+_65504067 0.35 ENSMUST00000224629.2
F-box protein 16
chr6_-_57340712 0.34 ENSMUST00000228156.2
ENSMUST00000227186.2
ENSMUST00000228294.2
ENSMUST00000228342.2
vomeronasal 1 receptor 17
chr7_+_103628383 0.34 ENSMUST00000098185.2
olfactory receptor 635
chr5_-_84565218 0.34 ENSMUST00000113401.4
Eph receptor A5
chr16_-_29363671 0.33 ENSMUST00000039090.9
ATPase type 13A4
chr6_-_128339654 0.32 ENSMUST00000203719.2
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr4_+_136038263 0.30 ENSMUST00000105850.8
ENSMUST00000148843.10
heterogeneous nuclear ribonucleoprotein R
chr1_+_82817794 0.29 ENSMUST00000186043.2
ArfGAP with FG repeats 1
chr1_-_37996838 0.29 ENSMUST00000027254.10
ENSMUST00000114894.2
lysozyme G-like 1
chr13_-_103042294 0.28 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr6_+_57405915 0.28 ENSMUST00000227909.2
vomeronasal 1 receptor 20
chr10_+_129539079 0.27 ENSMUST00000213331.2
olfactory receptor 804
chr18_+_24737009 0.26 ENSMUST00000234266.2
ENSMUST00000025120.8
elongator acetyltransferase complex subunit 2
chr14_-_52341426 0.26 ENSMUST00000227536.2
ENSMUST00000227195.2
ENSMUST00000228815.2
ENSMUST00000228198.2
ENSMUST00000227458.2
ENSMUST00000228232.2
ENSMUST00000227242.2
ENSMUST00000228748.2
heterogeneous nuclear ribonucleoprotein C
chr14_-_52277310 0.26 ENSMUST00000216907.2
ENSMUST00000214071.2
ENSMUST00000216188.2
olfactory receptor 221
chrX_+_159551171 0.24 ENSMUST00000112368.3
retinoschisis (X-linked, juvenile) 1 (human)
chr19_-_29344694 0.24 ENSMUST00000138051.2
plasminogen receptor, C-terminal lysine transmembrane protein
chr8_+_34089597 0.23 ENSMUST00000009774.11
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr2_+_87725306 0.23 ENSMUST00000217436.2
olfactory receptor 1153
chr5_+_134961205 0.22 ENSMUST00000047196.14
ENSMUST00000111221.9
ENSMUST00000111219.8
ENSMUST00000068617.12
methyltransferase like 27
chr7_+_101546059 0.22 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chr4_+_136038301 0.22 ENSMUST00000084219.12
heterogeneous nuclear ribonucleoprotein R
chr17_-_37974666 0.21 ENSMUST00000215414.2
ENSMUST00000213638.3
olfactory receptor 117
chr14_-_44987797 0.21 ENSMUST00000226900.2
predicted gene 8267
chr17_+_46807637 0.21 ENSMUST00000046497.8
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr14_-_52341472 0.20 ENSMUST00000111610.12
ENSMUST00000164655.2
heterogeneous nuclear ribonucleoprotein C
chr4_-_112291169 0.20 ENSMUST00000058605.3
selection and upkeep of intraepithelial T cells 9
chr2_-_168607166 0.19 ENSMUST00000137536.2
spalt like transcription factor 4
chr2_-_132089667 0.19 ENSMUST00000110163.8
ENSMUST00000180286.2
ENSMUST00000028816.9
transmembrane protein 230
chr16_+_51851917 0.18 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr4_+_136038243 0.17 ENSMUST00000131671.8
heterogeneous nuclear ribonucleoprotein R
chr10_+_129493563 0.17 ENSMUST00000217094.2
olfactory receptor 800
chr4_-_132191181 0.17 ENSMUST00000102567.4
mediator complex subunit 18
chr2_+_85804239 0.16 ENSMUST00000217244.2
olfactory receptor 1029
chr14_+_13803477 0.16 ENSMUST00000102996.4
CFAP20 domain containing
chr2_+_85809620 0.16 ENSMUST00000056849.3
olfactory receptor 1030
chr17_-_37404764 0.15 ENSMUST00000087144.5
olfactory receptor 91
chr2_-_89855921 0.14 ENSMUST00000216616.3
olfactory receptor 1264
chr7_+_29683373 0.13 ENSMUST00000148442.8
zinc finger protein 568
chr7_-_11414074 0.13 ENSMUST00000227010.2
ENSMUST00000209638.3
vomeronasal 1 receptor 72
chr17_+_21446349 0.13 ENSMUST00000235895.2
vomeronasal 1 receptor 234
chr1_+_190660689 0.13 ENSMUST00000066632.14
ENSMUST00000110899.7
angel homolog 2
chr10_-_129000620 0.13 ENSMUST00000214271.2
olfactory receptor 771
chr7_-_26895141 0.13 ENSMUST00000163311.9
ENSMUST00000126211.2
small nuclear ribonucleoprotein polypeptide A
chr11_-_100653754 0.12 ENSMUST00000107360.3
ENSMUST00000055083.4
hypocretin
chr11_-_22236795 0.12 ENSMUST00000180360.8
ENSMUST00000109563.9
EH domain binding protein 1
chr1_+_83022653 0.12 ENSMUST00000222567.2
predicted gene, 47969
chr8_-_22396428 0.11 ENSMUST00000051965.5
defensin beta 11
chr2_-_111100733 0.10 ENSMUST00000099619.6
olfactory receptor 1277
chr7_+_103652466 0.10 ENSMUST00000209757.3
olfactory receptor 638
chr1_+_88234454 0.09 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr6_+_37847721 0.09 ENSMUST00000031859.14
ENSMUST00000120428.8
tripartite motif-containing 24
chr7_-_44578834 0.09 ENSMUST00000107857.11
ENSMUST00000167930.8
ENSMUST00000085399.13
ENSMUST00000166972.9
adaptor-related protein complex 2, alpha 1 subunit
chr1_-_173161069 0.07 ENSMUST00000038227.6
atypical chemokine receptor 1 (Duffy blood group)
chr16_+_13176238 0.07 ENSMUST00000149359.2
myocardin related transcription factor B
chr15_+_81548090 0.06 ENSMUST00000023029.15
ENSMUST00000174229.8
ENSMUST00000172748.8
L3MBTL2 polycomb repressive complex 1 subunit
chr2_-_89972637 0.06 ENSMUST00000215659.2
ENSMUST00000215765.2
ENSMUST00000213293.2
ENSMUST00000214973.2
ENSMUST00000215153.3
olfactory receptor 32
chr18_+_4993795 0.06 ENSMUST00000153016.8
supervillin
chr16_+_51851948 0.05 ENSMUST00000226593.2
Casitas B-lineage lymphoma b
chr1_+_172383499 0.04 ENSMUST00000061835.10
V-set and immunoglobulin domain containing 8
chr9_-_85631361 0.02 ENSMUST00000039213.15
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_-_12313274 0.02 ENSMUST00000208398.3
olfactory receptor 1438, pseudogene 1
chr10_-_129965752 0.02 ENSMUST00000215217.2
ENSMUST00000214192.2
olfactory receptor 824
chr2_-_157188568 0.01 ENSMUST00000029172.2
growth hormone releasing hormone
chr8_+_114362419 0.01 ENSMUST00000035777.10
MON1 homolog B, secretory traffciking associated

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0072312 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.3 3.8 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
1.2 4.7 GO:0000239 pachytene(GO:0000239)
0.4 2.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4 2.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.6 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.3 1.3 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 2.9 GO:0019532 oxalate transport(GO:0019532)
0.3 0.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 1.0 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.2 3.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.9 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.6 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 0.6 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.2 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.5 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 3.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.5 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 2.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 1.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 3.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.9 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 1.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 3.5 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 1.9 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 2.2 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.5 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0060187 cell pole(GO:0060187)
0.9 4.7 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.3 2.0 GO:0071547 piP-body(GO:0071547)
0.3 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 0.8 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.2 3.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 3.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.3 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 4.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.9 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.5 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 12.4 GO:0005581 collagen trimer(GO:0005581)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 3.6 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.6 GO:0099738 cell cortex region(GO:0099738)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.1 GO:0033691 sialic acid binding(GO:0033691)
0.9 4.7 GO:0034584 piRNA binding(GO:0034584)
0.4 1.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 2.8 GO:0019863 IgE binding(GO:0019863)
0.3 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 0.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 7.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.2 GO:0043495 protein anchor(GO:0043495)
0.1 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429) oligosaccharide binding(GO:0070492)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 3.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 12.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 12.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 3.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 2.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 4.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell