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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx2-2

Z-value: 0.90

Motif logo

Transcription factors associated with Nkx2-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000027434.12 Nkx2-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-2mm39_v1_chr2_-_147028309_147028331-0.753.9e-14Click!

Activity profile of Nkx2-2 motif

Sorted Z-values of Nkx2-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_174292471 6.89 ENSMUST00000016399.6
tubulin, beta 1 class VI
chr1_-_173703424 5.40 ENSMUST00000186442.7
myeloid nuclear differentiation antigen like
chr13_-_113237505 5.34 ENSMUST00000224282.2
ENSMUST00000023897.7
granzyme A
chr6_+_67873135 5.18 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr9_+_51124983 4.42 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chr19_-_11243530 4.32 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr6_-_41681273 4.10 ENSMUST00000031899.14
Kell blood group
chr17_+_18108102 4.08 ENSMUST00000054871.12
ENSMUST00000064068.5
formyl peptide receptor 3
formyl peptide receptor 2
chr1_-_73055043 3.94 ENSMUST00000027374.7
transition protein 1
chr10_-_117681864 3.94 ENSMUST00000064667.9
RAS related protein 1b
chr17_+_18108086 3.81 ENSMUST00000149944.2
formyl peptide receptor 2
chr2_-_58050494 3.69 ENSMUST00000028175.7
cytohesin 1 interacting protein
chr6_-_136834725 3.61 ENSMUST00000032341.3
ADP-ribosyltransferase 4
chr6_+_68233361 3.50 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chr6_+_65929546 3.38 ENSMUST00000043382.9
RIKEN cDNA 4930544G11 gene
chr5_-_88675700 3.33 ENSMUST00000087033.6
immunoglobulin joining chain
chr7_+_44485704 3.22 ENSMUST00000033015.8
interleukin 4 induced 1
chrX_+_106192510 3.19 ENSMUST00000147521.8
ENSMUST00000167673.2
purinergic receptor P2Y, G-protein coupled 10B
chr10_+_87926932 3.17 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chr2_-_84605732 3.00 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_+_72345801 2.98 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr16_+_14523696 2.96 ENSMUST00000023356.8
snail family zinc finger 2
chr11_-_79414542 2.95 ENSMUST00000179322.2
ecotropic viral integration site 2b
chr15_-_5093222 2.85 ENSMUST00000110689.5
complement component 7
chr2_-_84605764 2.84 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr5_-_82271183 2.80 ENSMUST00000186079.2
ENSMUST00000185607.2
RIKEN cDNA 1700031L13 gene
chr10_-_59277570 2.77 ENSMUST00000009798.5
oncoprotein induced transcript 3
chr1_-_173426640 2.73 ENSMUST00000150649.9
ENSMUST00000180215.2
ENSMUST00000097462.9
interferon activated gene 213
chr8_-_79975199 2.70 ENSMUST00000034109.6
RIKEN cDNA 1700011L22 gene
chr12_-_112824506 2.65 ENSMUST00000021729.9
G protein-coupled receptor 132
chr2_-_83771564 2.65 ENSMUST00000038223.8
ENSMUST00000152829.2
zinc finger SWIM-type containing 2
chr1_-_85664246 2.64 ENSMUST00000064788.14
RIKEN cDNA A630001G21 gene
chr8_-_25438784 2.61 ENSMUST00000119720.8
ENSMUST00000121438.9
a disintegrin and metallopeptidase domain 32
chr6_-_23650205 2.43 ENSMUST00000115354.2
ring finger protein 133
chr11_+_96209093 2.41 ENSMUST00000049241.9
homeobox B4
chr2_+_3705824 2.39 ENSMUST00000115054.9
family with sequence similarity 107, member B
chr7_+_45067747 2.33 ENSMUST00000238638.2
luteinizing hormone beta
chr8_-_3976808 2.32 ENSMUST00000188386.2
ENSMUST00000084086.9
ENSMUST00000171635.8
CD209b antigen
chr6_-_3494587 2.29 ENSMUST00000049985.15
HEPACAM family member 2
chr1_-_165830160 2.26 ENSMUST00000111429.11
ENSMUST00000176800.2
ENSMUST00000177358.8
POU domain, class 2, transcription factor 1
chr18_+_43897354 2.21 ENSMUST00000187157.7
ENSMUST00000043803.13
ENSMUST00000189750.2
secretoglobin, family 3A, member 2
chr11_+_105885461 2.19 ENSMUST00000190995.2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr6_+_67586695 2.18 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr14_-_49482846 2.13 ENSMUST00000227113.2
ENSMUST00000130853.2
ENSMUST00000228936.2
ENSMUST00000022398.15
coiled-coil domain containing 198
chr3_-_107893676 2.13 ENSMUST00000066530.7
ENSMUST00000012348.9
glutathione S-transferase, mu 2
chr1_+_173501215 2.10 ENSMUST00000085876.12
interferon activated gene 208
chr2_+_127750978 2.04 ENSMUST00000110344.2
acyl-Coenzyme A oxidase-like
chr6_-_23650297 2.04 ENSMUST00000063548.4
ring finger protein 133
chr4_-_45532470 2.03 ENSMUST00000147448.2
src homology 2 domain-containing transforming protein B
chr11_-_79971750 2.03 ENSMUST00000103233.10
ENSMUST00000061283.15
cytokine receptor-like factor 3
chr7_-_122969064 1.99 ENSMUST00000207010.2
ENSMUST00000167309.8
ENSMUST00000205262.2
ENSMUST00000106442.9
ENSMUST00000098060.5
Rho GTPase activating protein 17
chr13_-_20008397 1.97 ENSMUST00000222664.2
ENSMUST00000065335.3
G protein-coupled receptor 141
chr11_+_48691175 1.93 ENSMUST00000020640.8
receptor for activated C kinase 1
chr7_+_122969004 1.91 ENSMUST00000206721.2
leucine carboxyl methyltransferase 1
chr3_+_108646974 1.90 ENSMUST00000133931.9
AKNA domain containing 1
chr7_+_121333700 1.87 ENSMUST00000000221.6
sodium channel, nonvoltage-gated 1 gamma
chr10_+_57521930 1.86 ENSMUST00000177325.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr12_+_78240999 1.84 ENSMUST00000211288.3
predicted gene 6657
chr1_-_165830187 1.82 ENSMUST00000184643.8
ENSMUST00000160908.8
ENSMUST00000027850.15
ENSMUST00000160260.9
POU domain, class 2, transcription factor 1
chr3_-_49711765 1.81 ENSMUST00000035931.13
protocadherin 18
chr14_-_101846459 1.80 ENSMUST00000161991.8
TBC1 domain family, member 4
chr13_-_19917092 1.80 ENSMUST00000151029.3
G protein-coupled receptor 141B
chr16_-_85347305 1.78 ENSMUST00000175700.8
ENSMUST00000114174.3
cysteine and tyrosine-rich protein 1
chr8_+_46387647 1.76 ENSMUST00000095326.10
coiled-coil domain containing 110
chrX_+_106193167 1.75 ENSMUST00000137107.2
ENSMUST00000067249.3
purinergic receptor P2Y, G-protein coupled 10B
chr5_+_67125759 1.74 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr14_-_56026266 1.73 ENSMUST00000168716.8
ENSMUST00000178399.3
ENSMUST00000022830.14
receptor-interacting serine-threonine kinase 3
chr5_+_11392646 1.72 ENSMUST00000179482.2
spermatogenesis associated glutamate (E)-rich protein 1
chr5_+_11821653 1.72 ENSMUST00000178158.2
predicted gene 8926
chr6_-_73446560 1.68 ENSMUST00000070163.6
RIKEN cDNA 4931417E11 gene
chr9_+_108225026 1.65 ENSMUST00000035237.12
ENSMUST00000194959.6
ubiquitin specific peptidase 4 (proto-oncogene)
chr5_+_149363168 1.63 ENSMUST00000201683.4
ENSMUST00000202920.4
testis expressed 26
chr18_-_44308126 1.63 ENSMUST00000066328.5
serine protease inhibitor, Kazal type-like
chr14_+_32713387 1.63 ENSMUST00000123822.8
ENSMUST00000120951.2
leucine rich repeat containing 18
chr18_-_3309858 1.62 ENSMUST00000144496.8
ENSMUST00000154715.8
cAMP responsive element modulator
chr13_-_76453191 1.62 ENSMUST00000208418.2
family with sequence similarity 81, member B
chr14_-_42872221 1.58 ENSMUST00000100694.5
predicted gene 10376
chr5_-_110987441 1.58 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr4_+_102843540 1.57 ENSMUST00000030248.12
ENSMUST00000125417.9
ENSMUST00000169211.3
dynein light chain Tctex-type 5
chr5_+_11733203 1.55 ENSMUST00000178989.2
predicted gene 8922
chrX_+_106193060 1.54 ENSMUST00000125676.8
ENSMUST00000180182.2
purinergic receptor P2Y, G-protein coupled 10B
chr14_+_32713336 1.52 ENSMUST00000038956.12
leucine rich repeat containing 18
chr3_-_130524024 1.52 ENSMUST00000079085.11
ribosomal protein L34
chr5_-_34326847 1.50 ENSMUST00000202042.2
ENSMUST00000060049.8
HAUS augmin-like complex, subunit 3
chr5_+_11178835 1.50 ENSMUST00000178863.2
predicted gene 8879
chr5_+_67125902 1.50 ENSMUST00000127184.8
LIM and calponin homology domains 1
chr5_+_11467593 1.50 ENSMUST00000179679.2
predicted gene 8897
chr8_+_46984016 1.48 ENSMUST00000152423.2
acyl-CoA synthetase long-chain family member 1
chr2_-_140231618 1.47 ENSMUST00000122367.8
ENSMUST00000120133.2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr13_-_67080968 1.44 ENSMUST00000172597.8
ENSMUST00000173773.2
mitochondrial transcription termination factor 3
chr17_+_7592045 1.44 ENSMUST00000095726.11
ENSMUST00000128533.8
ENSMUST00000129709.8
ENSMUST00000147803.8
ENSMUST00000140192.8
ENSMUST00000138222.8
ENSMUST00000144861.2
t-complex protein 10a
chr3_-_49711706 1.44 ENSMUST00000191794.2
protocadherin 18
chr6_+_68402550 1.44 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr11_+_23234644 1.43 ENSMUST00000150750.3
exportin 1
chr14_+_24540745 1.42 ENSMUST00000112384.10
ribosomal protein S24
chr10_-_13053733 1.42 ENSMUST00000019954.6
zinc finger, C2HC-type containing 1B
chrX_+_110154017 1.41 ENSMUST00000210720.3
cylicin, basic protein of sperm head cytoskeleton 1
chr19_+_6097083 1.41 ENSMUST00000134667.8
synovial apoptosis inhibitor 1, synoviolin
chr14_-_59632830 1.41 ENSMUST00000166912.3
PHD finger protein 11C
chr11_+_75521800 1.40 ENSMUST00000006286.9
inositol polyphosphate 5-phosphatase K
chr3_-_105940130 1.40 ENSMUST00000200146.2
chitinase-like 5
chr6_-_120334382 1.39 ENSMUST00000032283.12
coiled-coil domain containing 77
chr5_-_35897331 1.37 ENSMUST00000201511.2
SH3 domain and tetratricopeptide repeats 1
chr10_+_79500387 1.37 ENSMUST00000020554.8
mucosal vascular addressin cell adhesion molecule 1
chr5_+_11234174 1.37 ENSMUST00000168407.3
predicted gene 5861
chr19_+_6097111 1.35 ENSMUST00000025723.9
synovial apoptosis inhibitor 1, synoviolin
chr6_-_70769135 1.34 ENSMUST00000066134.6
ribose 5-phosphate isomerase A
chr5_+_11553780 1.34 ENSMUST00000179375.2
predicted gene 8906
chr18_+_20443795 1.33 ENSMUST00000077146.4
desmoglein 1 alpha
chr12_+_78243846 1.32 ENSMUST00000188791.2
predicted gene 6657
chr17_+_43671314 1.32 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr9_-_107512566 1.30 ENSMUST00000055704.12
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr5_+_149363114 1.30 ENSMUST00000031667.8
testis expressed 26
chr4_+_115420876 1.30 ENSMUST00000126645.8
ENSMUST00000030480.4
cytochrome P450, family 4, subfamily a, polypeptide 31
chr12_+_33003882 1.29 ENSMUST00000076698.13
synaptophysin-like protein
chr6_+_137731526 1.28 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
deoxyribose-phosphate aldolase (putative)
chr6_+_21985902 1.27 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr16_+_32315076 1.27 ENSMUST00000064192.8
zinc finger, DHHC domain containing 19
chr11_+_68393845 1.24 ENSMUST00000102613.8
ENSMUST00000060441.7
phosphoinositide-3-kinase regulatory subunit 5
chr11_-_115078147 1.24 ENSMUST00000103038.8
ENSMUST00000103039.2
ENSMUST00000103040.11
N-acetyltransferase 9 (GCN5-related, putative)
chr14_+_54000594 1.23 ENSMUST00000103589.6
T cell receptor alpha variable 14-3
chr15_-_10470575 1.23 ENSMUST00000136591.8
DnaJ heat shock protein family (Hsp40) member C21
chr16_+_23338960 1.22 ENSMUST00000211460.2
ENSMUST00000210658.2
ENSMUST00000209198.2
ENSMUST00000210371.2
ENSMUST00000211499.2
ENSMUST00000210795.2
ENSMUST00000209422.2
predicted gene 45338
receptor transporter protein 4
chr13_+_47347301 1.22 ENSMUST00000110111.4
ring finger protein 144B
chr6_+_122967309 1.21 ENSMUST00000079379.3
C-type lectin domain family 4, member a4
chr13_-_103901010 1.20 ENSMUST00000210489.2
splicing regulatory glutamine/lysine-rich protein 1
chrX_+_67864699 1.20 ENSMUST00000096420.3
predicted gene 14698
chr6_+_67816777 1.19 ENSMUST00000200578.5
ENSMUST00000103308.3
immunoglobulin kappa variable 9-129
chr3_-_75177378 1.19 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr1_-_161807205 1.18 ENSMUST00000162676.2
RIKEN cDNA 4930558K02 gene
chr6_+_5390386 1.18 ENSMUST00000183358.2
ankyrin repeat and SOCS box-containing 4
chr6_-_120334400 1.18 ENSMUST00000112703.8
coiled-coil domain containing 77
chr5_+_11307124 1.18 ENSMUST00000177727.2
predicted gene 8890
chr16_+_32315090 1.17 ENSMUST00000231510.2
zinc finger, DHHC domain containing 19
chr3_-_6685492 1.17 ENSMUST00000091364.4
RIKEN cDNA 1700008P02 gene
chrX_+_106836189 1.17 ENSMUST00000101292.9
terminal nucleotidyltransferase 5D
chr14_+_53994813 1.17 ENSMUST00000180380.3
T cell receptor alpha variable 13-4-DV7
chr6_+_68026941 1.16 ENSMUST00000103316.2
immunoglobulin kappa chain variable 9-120
chr15_-_102259158 1.16 ENSMUST00000231061.2
ENSMUST00000041208.9
achalasia, adrenocortical insufficiency, alacrimia
chr1_-_69723316 1.15 ENSMUST00000190855.7
ENSMUST00000188110.7
ENSMUST00000191262.7
IKAROS family zinc finger 2
chr4_-_108075119 1.13 ENSMUST00000223127.2
ENSMUST00000043793.7
ENSMUST00000106690.9
zyg-11 family member A, cell cycle regulator
chr6_+_137731599 1.12 ENSMUST00000204356.2
deoxyribose-phosphate aldolase (putative)
chr2_+_51962831 1.12 ENSMUST00000112693.10
replication timing regulatory factor 1
chr1_-_155910567 1.11 ENSMUST00000141878.8
torsin A interacting protein 1
chr11_+_78192355 1.10 ENSMUST00000045026.4
sperm associated antigen 5
chr9_-_106768601 1.09 ENSMUST00000069036.14
mesencephalic astrocyte-derived neurotrophic factor
chr17_+_79934096 1.08 ENSMUST00000224618.2
regulator of microtubule dynamics 2
chr15_+_66542598 1.08 ENSMUST00000065916.14
thyroglobulin
chr17_+_79919267 1.08 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr2_-_152857239 1.06 ENSMUST00000028972.9
p53 and DNA damage regulated 1
chr13_+_23940964 1.05 ENSMUST00000102965.4
H4 clustered histone 2
chr5_-_110987604 1.05 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr11_-_45845992 1.05 ENSMUST00000109254.2
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr19_-_46950948 1.04 ENSMUST00000236924.2
5'-nucleotidase, cytosolic II
chr3_-_104771716 1.03 ENSMUST00000195912.2
ENSMUST00000094028.10
capping protein (actin filament) muscle Z-line, alpha 1
chrX_+_61511597 1.02 ENSMUST00000033537.2
RIKEN cDNA 4931400O07 gene
chr6_-_50631418 1.02 ENSMUST00000031853.8
neuropeptide VF precursor
chr12_+_105996961 1.02 ENSMUST00000220629.2
vaccinia related kinase 1
chr5_-_83502966 1.01 ENSMUST00000053543.11
trans-2,3-enoyl-CoA reductase-like
chr15_-_74869684 1.01 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
lymphocyte antigen 6 complex, locus A
chr9_+_39853511 1.00 ENSMUST00000062833.6
olfactory receptor 974
chr15_+_6552270 1.00 ENSMUST00000226412.2
FYN binding protein
chr7_+_19079058 0.99 ENSMUST00000160369.8
excision repair cross-complementing rodent repair deficiency, complementation group 1
chr5_+_110988095 0.98 ENSMUST00000198373.2
checkpoint kinase 2
chrX_+_100317629 0.98 ENSMUST00000117706.8
mediator complex subunit 12
chr6_+_21986445 0.97 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr14_+_24540777 0.96 ENSMUST00000169826.3
ENSMUST00000225023.2
ENSMUST00000223999.2
ribosomal protein S24
chr3_-_98496123 0.95 ENSMUST00000178221.4
predicted gene 10681
chr3_+_137849189 0.95 ENSMUST00000040321.13
tRNA methyltransferase 10A
chr14_-_73286504 0.94 ENSMUST00000044664.12
cysteinyl leukotriene receptor 2
chr5_+_110987839 0.94 ENSMUST00000200172.2
ENSMUST00000066160.3
checkpoint kinase 2
chr1_+_40478787 0.93 ENSMUST00000097772.10
interleukin 1 receptor-like 1
chr7_-_43906802 0.92 ENSMUST00000107945.8
ENSMUST00000118216.8
acid phosphatase 4
chr14_+_53666165 0.92 ENSMUST00000180549.3
T cell receptor alpha variable 6-3
chr14_-_73286535 0.90 ENSMUST00000169168.3
cysteinyl leukotriene receptor 2
chr18_-_3280999 0.89 ENSMUST00000049942.13
cAMP responsive element modulator
chr1_-_66984178 0.88 ENSMUST00000027151.12
myosin, light polypeptide 1
chr6_-_67931692 0.87 ENSMUST00000103313.3
immunoglobulin kappa variable 9-123
chr6_+_68495964 0.87 ENSMUST00000199510.5
ENSMUST00000103325.3
immunoglobulin kappa chain variable 14-100
chr2_-_140012447 0.87 ENSMUST00000046030.8
ESF1 nucleolar pre-rRNA processing protein homolog
chr11_-_115078653 0.87 ENSMUST00000103041.8
N-acetyltransferase 9 (GCN5-related, putative)
chrX_+_115358631 0.87 ENSMUST00000101269.2
CPX chromosome region, candidate 1
chr14_+_52962756 0.87 ENSMUST00000181483.3
T cell receptor alpha variable 6D-3
chr1_-_155910546 0.86 ENSMUST00000169241.8
torsin A interacting protein 1
chr17_-_3746536 0.85 ENSMUST00000115800.2
NADPH oxidase 3
chr9_+_35470752 0.85 ENSMUST00000034615.10
ENSMUST00000121246.2
pseudouridine synthase 3
chr17_-_34846323 0.84 ENSMUST00000168709.3
ENSMUST00000064953.15
ENSMUST00000170345.8
ENSMUST00000171121.9
ENSMUST00000168391.9
ENSMUST00000169067.9
predicted gene 20460
palmitoyl-protein thioesterase 2
chr3_-_98471301 0.84 ENSMUST00000058728.10
predicted gene 10681
chrX_+_125947591 0.84 ENSMUST00000096332.2
predicted gene 382
chr6_-_120334302 0.84 ENSMUST00000163827.8
coiled-coil domain containing 77
chr12_-_83534482 0.84 ENSMUST00000177959.8
ENSMUST00000178756.8
D4, zinc and double PHD fingers, family 3
chr6_-_142268667 0.83 ENSMUST00000128446.2
solute carrier organic anion transporter family, member 1a5
chr18_-_3281752 0.82 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr9_-_119151428 0.82 ENSMUST00000040853.11
oxidative-stress responsive 1
chr3_-_57202301 0.82 ENSMUST00000171384.8
transmembrane 4 superfamily member 1
chr2_-_73284262 0.81 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr13_-_38220899 0.81 ENSMUST00000110233.8
ENSMUST00000074969.11
ENSMUST00000131066.2
cancer antigen 1
chrX_+_143239577 0.80 ENSMUST00000155206.8
transient receptor potential cation channel, subfamily C, member 5, opposite strand
chr11_+_67061908 0.79 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr11_-_69791756 0.79 ENSMUST00000018714.13
ENSMUST00000128046.2
RIKEN cDNA 2810408A11 gene

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.2 8.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.1 3.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
1.0 3.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.8 3.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.7 4.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.6 4.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.5 5.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.5 1.9 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 1.9 GO:0051325 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.4 3.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 1.7 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.4 1.6 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.4 2.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.4 1.9 GO:0006481 C-terminal protein methylation(GO:0006481)
0.4 1.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4 1.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.4 2.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.4 1.4 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.3 1.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 3.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 2.3 GO:0001878 response to yeast(GO:0001878)
0.3 1.0 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.3 2.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 2.4 GO:0048539 bone marrow development(GO:0048539)
0.3 0.9 GO:0009629 response to gravity(GO:0009629)
0.3 0.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 1.0 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.2 0.7 GO:0060197 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) cloacal septation(GO:0060197)
0.2 0.7 GO:0051542 elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 2.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.5 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.2 1.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 1.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.2 1.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.6 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 3.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 3.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.4 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 1.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.3 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1 2.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 1.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 2.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 1.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.9 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 3.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 3.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 1.0 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.3 GO:0030728 ovulation(GO:0030728)
0.1 0.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 3.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.1 2.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.6 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.1 2.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 4.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.8 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.0 5.6 GO:0051225 spindle assembly(GO:0051225)
0.0 11.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.0 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.8 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.7 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 3.3 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 2.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0006577 amino-acid betaine metabolic process(GO:0006577)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 2.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.4 GO:0042255 ribosome assembly(GO:0042255)
0.0 1.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.1 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 3.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 5.4 GO:0042113 B cell activation(GO:0042113)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 3.4 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.7 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.5 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0007602 phototransduction(GO:0007602)
0.0 1.0 GO:0051289 protein homotetramerization(GO:0051289)
0.0 2.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.8 GO:0007605 sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.4 2.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.4 1.4 GO:0043159 acrosomal matrix(GO:0043159)
0.3 1.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 2.8 GO:0005579 membrane attack complex(GO:0005579)
0.3 3.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.7 GO:0097342 ripoptosome(GO:0097342)
0.2 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.5 GO:0070652 HAUS complex(GO:0070652)
0.2 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0005713 recombination nodule(GO:0005713)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.1 GO:0001940 male pronucleus(GO:0001940)
0.1 1.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.0 GO:0071203 WASH complex(GO:0071203)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 3.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:0016460 myosin II complex(GO:0016460)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 7.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 3.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 3.0 GO:0005882 intermediate filament(GO:0005882)
0.0 3.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 3.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 4.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.1 3.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.8 3.3 GO:0019862 IgA binding(GO:0019862)
0.5 1.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.5 1.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 1.6 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.4 1.9 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.4 1.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.4 2.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.4 2.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 1.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 1.0 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.3 1.5 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.3 0.6 GO:0004875 complement receptor activity(GO:0004875)
0.3 3.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 1.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 2.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 5.8 GO:0001848 complement binding(GO:0001848)
0.2 3.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 1.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.2 1.6 GO:0031685 adenosine receptor binding(GO:0031685)
0.2 4.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.7 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 1.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.2 1.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 1.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 2.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 4.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 4.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 2.3 GO:0005537 mannose binding(GO:0005537)
0.1 1.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 5.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 3.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 13.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 2.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 3.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0001601 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 2.6 GO:0043621 protein self-association(GO:0043621)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 1.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 7.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.8 PID ATM PATHWAY ATM pathway
0.1 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 4.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 11.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases