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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx2-4

Z-value: 0.93

Motif logo

Transcription factors associated with Nkx2-4

Gene Symbol Gene ID Gene Info
ENSMUSG00000054160.3 Nkx2-4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-4mm39_v1_chr2_-_146927365_1469274060.253.1e-02Click!

Activity profile of Nkx2-4 motif

Sorted Z-values of Nkx2-4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_41107047 6.82 ENSMUST00000103271.2
T cell receptor beta, variable 13-3
chr6_+_41098273 4.55 ENSMUST00000103270.4
T cell receptor beta, variable 13-2
chrX_+_106132840 3.74 ENSMUST00000118666.8
ENSMUST00000053375.4
purinergic receptor P2Y, G-protein coupled 10
chr15_-_100567377 3.58 ENSMUST00000182814.8
ENSMUST00000238935.2
ENSMUST00000182068.8
ENSMUST00000182574.2
ENSMUST00000182775.8
bridging integrator 2
chr15_-_100567412 3.45 ENSMUST00000183211.8
bridging integrator 2
chr4_-_129467430 3.28 ENSMUST00000102596.8
lymphocyte protein tyrosine kinase
chr15_-_78449172 3.23 ENSMUST00000230952.2
Rac family small GTPase 2
chr9_-_14815228 3.03 ENSMUST00000034409.14
ENSMUST00000117620.8
IZUMO1 receptor, JUNO
chr2_+_154390808 2.79 ENSMUST00000045116.11
ENSMUST00000109709.4
RIKEN cDNA 1700003F12 gene
chr2_+_174485327 2.72 ENSMUST00000059452.6
zinc finger protein 831
chr1_+_59669482 2.71 ENSMUST00000190490.2
predicted gene 973
chr17_-_57501170 2.66 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr8_-_110305672 2.59 ENSMUST00000074898.8
haptoglobin
chr5_+_35156389 2.35 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr1_+_100025486 2.35 ENSMUST00000188735.2
contactin associated protein-like 5B
chr2_+_61634797 2.28 ENSMUST00000048934.15
T-box brain transcription factor 1
chr6_+_29398919 2.18 ENSMUST00000181464.8
ENSMUST00000180829.8
coiled-coil domain containing 136
chrX_-_35755483 2.14 ENSMUST00000169499.2
predicted gene 14569
chr13_+_83723255 2.07 ENSMUST00000199167.5
ENSMUST00000195904.5
myocyte enhancer factor 2C
chr7_+_54485336 2.06 ENSMUST00000082373.8
leucine zipper protein 2
chr1_-_175319842 2.00 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr1_-_28819331 1.98 ENSMUST00000059937.5
predicted gene 597
chr15_+_6552270 1.95 ENSMUST00000226412.2
FYN binding protein
chr2_-_84865831 1.90 ENSMUST00000028465.14
purinergic receptor P2X, ligand-gated ion channel, 3
chr10_+_87926932 1.90 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chr13_+_83723743 1.89 ENSMUST00000198217.5
ENSMUST00000199210.5
myocyte enhancer factor 2C
chr17_+_70828649 1.81 ENSMUST00000233283.2
DLG associated protein 1
chr17_+_70829050 1.80 ENSMUST00000133717.9
ENSMUST00000148486.8
DLG associated protein 1
chr7_-_80554807 1.80 ENSMUST00000119428.2
ENSMUST00000026817.11
neuromedin B
chr5_+_35156454 1.77 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr14_+_53853772 1.75 ENSMUST00000180972.3
T cell receptor alpha variable 12-2
chr3_-_92496293 1.74 ENSMUST00000098888.7
sperm mitochondria-associated cysteine-rich protein
chr19_-_39637489 1.69 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr18_+_37085673 1.66 ENSMUST00000192512.6
ENSMUST00000192295.2
ENSMUST00000115661.5
protocadherin alpha 4
predicted gene, 42416
chr11_+_110858842 1.66 ENSMUST00000180023.8
ENSMUST00000106636.8
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_88133472 1.62 ENSMUST00000119972.4
DnaJ heat shock protein family (Hsp40) member B3
chr3_-_102843406 1.56 ENSMUST00000199930.2
ENSMUST00000029448.11
ENSMUST00000196988.5
synaptonemal complex protein 1
chr18_+_44096300 1.55 ENSMUST00000069245.8
serine peptidase inhibitor, Kazal type 5
chr14_+_53878403 1.53 ENSMUST00000184874.2
T cell receptor alpha variable 14-2
chr13_+_47347301 1.52 ENSMUST00000110111.4
ring finger protein 144B
chr17_+_70829144 1.47 ENSMUST00000140728.8
DLG associated protein 1
chr3_-_92926364 1.46 ENSMUST00000193944.2
ENSMUST00000029520.9
late cornified envelope 1M
chr6_-_122587005 1.45 ENSMUST00000032211.5
growth differentiation factor 3
chr5_-_23821523 1.45 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr1_+_85454323 1.44 ENSMUST00000239236.2
predicted gene 7592
chr3_+_153549846 1.43 ENSMUST00000044089.4
ankyrin repeat and SOCS box-containing 17
chr6_-_97037366 1.41 ENSMUST00000089295.6
TAFA chemokine like family member 4
chr13_+_35843816 1.37 ENSMUST00000075220.14
chromodomain protein, Y chromosome-like
chr10_+_4561974 1.35 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr8_-_79539838 1.34 ENSMUST00000146824.2
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_+_14564932 1.32 ENSMUST00000182407.8
ENSMUST00000030691.17
piccolo (presynaptic cytomatrix protein)
chr6_-_98319684 1.32 ENSMUST00000164491.3
MyoD family inhibitor domain containing 2
chr6_+_142359099 1.28 ENSMUST00000126521.9
ENSMUST00000211094.2
spexin hormone
chr17_+_69071546 1.26 ENSMUST00000233625.2
L3MBTL4 histone methyl-lysine binding protein
chrX_+_102674181 1.24 ENSMUST00000033692.9
zinc finger, CCHC domain containing 13
chr1_+_175526152 1.21 ENSMUST00000094288.10
ENSMUST00000171939.8
WD repeat domain 64
chr6_-_29164981 1.21 ENSMUST00000007993.16
RNA binding motif protein 28
chr8_+_46081213 1.18 ENSMUST00000130850.8
sorbin and SH3 domain containing 2
chr13_+_83672965 1.16 ENSMUST00000199432.5
ENSMUST00000198069.5
ENSMUST00000197681.5
ENSMUST00000197722.5
ENSMUST00000197938.5
myocyte enhancer factor 2C
chr3_-_108108113 1.15 ENSMUST00000106655.2
ENSMUST00000065664.7
cytochrome b-561 domain containing 1
chr15_-_76419131 1.15 ENSMUST00000230604.2
transmembrane protein 249
chr5_-_122188165 1.12 ENSMUST00000154139.8
cut-like homeobox 2
chr2_+_29951859 1.10 ENSMUST00000102866.10
SET nuclear oncogene
chrX_-_142716200 1.07 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr2_-_34645241 1.05 ENSMUST00000102800.9
GTPase activating protein and VPS9 domains 1
chr3_-_10366229 1.02 ENSMUST00000119761.2
ENSMUST00000029043.13
fatty acid binding protein 12
chr6_-_28133324 1.02 ENSMUST00000131897.2
glutamate receptor, metabotropic 8
chr8_-_3904309 1.00 ENSMUST00000033888.5
CD209e antigen
chr19_+_5497575 1.00 ENSMUST00000025850.7
ENSMUST00000236774.2
fos-like antigen 1
chr6_+_30568366 0.98 ENSMUST00000049251.6
carboxypeptidase A4
chr10_+_128067964 0.96 ENSMUST00000125289.8
ENSMUST00000105242.8
timeless circadian clock 1
chr11_+_101623776 0.95 ENSMUST00000039152.14
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr2_-_27397668 0.94 ENSMUST00000154316.8
bromodomain containing 3
chr18_-_3281752 0.94 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr15_+_99568208 0.94 ENSMUST00000023758.9
acid-sensing (proton-gated) ion channel 1
chr6_+_96090127 0.89 ENSMUST00000122120.8
TAFA chemokine like family member 1
chr15_+_21111428 0.89 ENSMUST00000075132.8
cadherin 12
chr12_-_81468705 0.88 ENSMUST00000085319.4
a disintegrin and metallopeptidase domain 4
chrY_+_17400761 0.88 ENSMUST00000179408.3
RNA binding motif 31, Y-linked
chr2_+_131792774 0.87 ENSMUST00000110170.8
ENSMUST00000110172.9
ENSMUST00000110171.9
prion like protein doppel
chr14_-_32110312 0.87 ENSMUST00000100723.4
RIKEN cDNA 1700024G13 gene
chr1_+_85177316 0.86 ENSMUST00000161424.5
ENSMUST00000113402.4
predicted pseudogene 7609
chr19_-_39875192 0.85 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr6_+_41331039 0.85 ENSMUST00000072103.7
trypsin 10
chr4_-_136620376 0.83 ENSMUST00000046332.6
complement component 1, q subcomponent, C chain
chr8_+_46080840 0.78 ENSMUST00000135336.9
sorbin and SH3 domain containing 2
chr14_+_53061814 0.77 ENSMUST00000103648.4
T cell receptor alpha variable 11D
chr11_+_87483723 0.74 ENSMUST00000119628.8
myotubularin related protein 4
chr12_+_105996961 0.72 ENSMUST00000220629.2
vaccinia related kinase 1
chr3_+_76500857 0.71 ENSMUST00000162471.2
follistatin-like 5
chr5_+_24890810 0.71 ENSMUST00000068825.8
negative regulator of ubiquitin-like proteins 1
chr14_+_73376192 0.68 ENSMUST00000171070.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_+_128067934 0.67 ENSMUST00000055539.11
ENSMUST00000105244.8
ENSMUST00000105243.9
timeless circadian clock 1
chr11_-_101490011 0.67 ENSMUST00000209862.2
ENSMUST00000154147.2
predicted gene 11634
chr18_-_3281089 0.67 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr9_-_39618413 0.66 ENSMUST00000215192.2
olfactory receptor 149
chr2_-_85027041 0.63 ENSMUST00000099930.9
ENSMUST00000111601.2
leucine rich repeat containing 55
chr14_+_53081922 0.62 ENSMUST00000181360.3
ENSMUST00000183652.2
T cell receptor alpha variable 12D-1
chr15_-_98796373 0.60 ENSMUST00000229775.2
ENSMUST00000023737.6
desert hedgehog
chr1_-_63153675 0.60 ENSMUST00000097718.9
INO80 complex subunit D
chr3_+_88536805 0.59 ENSMUST00000175745.2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr6_+_121320339 0.58 ENSMUST00000168295.2
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr2_-_63014622 0.58 ENSMUST00000075052.10
ENSMUST00000112454.8
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr2_+_153716958 0.58 ENSMUST00000028983.3
BPI fold containing family B, member 2
chr11_+_110858882 0.57 ENSMUST00000125692.2
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_-_142716085 0.57 ENSMUST00000087313.10
doublecortin
chr11_+_101623836 0.56 ENSMUST00000129741.2
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr6_-_28133128 0.56 ENSMUST00000132755.2
glutamate receptor, metabotropic 8
chr15_-_27788693 0.52 ENSMUST00000226287.2
triple functional domain (PTPRF interacting)
chr2_-_35995283 0.50 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr14_-_8798841 0.50 ENSMUST00000061045.3
sentan, cilia apical structure protein
chr18_+_34675366 0.50 ENSMUST00000012426.3
wingless-type MMTV integration site family, member 8A
chr2_-_112089627 0.50 ENSMUST00000043970.2
NUT midline carcinoma, family member 1
chr1_+_85577766 0.49 ENSMUST00000066427.11
nuclear antigen Sp100
chrX_+_36528991 0.49 ENSMUST00000115194.5
reproductive homeobox 4A
chr4_+_62443606 0.47 ENSMUST00000062145.2
RIKEN cDNA 4933430I17 gene
chr5_-_120887864 0.47 ENSMUST00000053909.13
ENSMUST00000081491.13
2'-5' oligoadenylate synthetase 2
chr18_-_3281727 0.47 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chr19_-_39801188 0.46 ENSMUST00000162507.2
ENSMUST00000160476.9
ENSMUST00000239028.2
cytochrome P450, family 2, subfamily c, polypeptide 40
chrX_+_36572501 0.46 ENSMUST00000179915.4
reproductive homeobox 4A2
chr9_+_108437485 0.45 ENSMUST00000081111.14
ENSMUST00000193421.2
inosine monophosphate dehydrogenase 2
chr7_-_34512101 0.45 ENSMUST00000078686.8
ENSMUST00000205259.2
ENSMUST00000154629.3
carbohydrate sulfotransferase 8
chr9_-_57347366 0.45 ENSMUST00000214144.2
ENSMUST00000085709.6
ENSMUST00000214624.2
ENSMUST00000215883.2
ENSMUST00000214339.2
ENSMUST00000215299.2
ENSMUST00000214166.2
ENSMUST00000214065.2
phosphopantothenoylcysteine decarboxylase
chr5_-_137531471 0.43 ENSMUST00000143495.8
ENSMUST00000111020.8
ENSMUST00000111023.8
ENSMUST00000111038.8
guanine nucleotide binding protein (G protein), beta 2
erythropoietin
chr11_+_53611611 0.43 ENSMUST00000048605.3
interleukin 5
chr15_+_54274151 0.43 ENSMUST00000036737.4
collectin sub-family member 10
chr10_-_33662700 0.41 ENSMUST00000223295.2
sulfotransferase family 3A, member 2
chr6_+_123206880 0.40 ENSMUST00000205129.2
C-type lectin domain family 4, member n
chr12_-_91712783 0.40 ENSMUST00000166967.2
stonin 2
chr8_+_67312847 0.39 ENSMUST00000118009.2
nuclear assembly factor 1 ribonucleoprotein
chr6_-_91784299 0.36 ENSMUST00000159684.8
glutamate receptor interacting protein 2
chr6_+_123206802 0.36 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chr2_+_131792931 0.36 ENSMUST00000110169.2
prion like protein doppel
chr14_-_52273600 0.36 ENSMUST00000214342.2
olfactory receptor 221
chr6_+_43212512 0.33 ENSMUST00000078057.4
olfactory receptor 47
chr14_-_79461316 0.32 ENSMUST00000040802.5
zinc finger protein 957
chrX_+_111513971 0.31 ENSMUST00000071814.13
zinc finger protein 711
chrX_+_147446594 0.30 ENSMUST00000101186.10
ENSMUST00000101190.11
predicted gene 15127
chr7_-_132414823 0.29 ENSMUST00000106165.8
family with sequence similarity 53, member B
chr17_+_37253916 0.28 ENSMUST00000173072.2
ring finger protein 39
chrX_+_55493325 0.27 ENSMUST00000079663.7
predicted gene 2174
chrX_+_146963720 0.27 ENSMUST00000112796.2
predicted gene 15107
chr6_+_70332836 0.26 ENSMUST00000103390.3
immunoglobulin kappa variable 8-18
chrX_+_147665572 0.26 ENSMUST00000163338.2
leucine zipper protein 4
chrX_-_72158969 0.25 ENSMUST00000114520.2
X-linked lymphocyte-regulated 5A
chr18_+_36431732 0.25 ENSMUST00000210490.3
IgA inducing protein
chrX_+_148567469 0.24 ENSMUST00000101180.8
predicted gene 15097
chrX_+_148377566 0.24 ENSMUST00000101181.5
predicted gene 10439
chrX_+_146572724 0.24 ENSMUST00000178833.2
predicted gene 15128
chr16_-_63684477 0.24 ENSMUST00000232654.2
ENSMUST00000064405.8
Eph receptor A3
chrX_+_72194740 0.23 ENSMUST00000097221.4
X-linked lymphocyte-regulated 5B
chrX_+_148230613 0.23 ENSMUST00000178169.2
predicted gene 15085
chrX_+_147871311 0.23 ENSMUST00000177606.8
ovary testis transcribed
chr3_-_110158280 0.22 ENSMUST00000190378.2
ENSMUST00000106567.2
protein arginine N-methyltransferase 6
chr11_-_83320281 0.22 ENSMUST00000052521.9
growth arrest-specific 2 like 2
chr8_+_46944000 0.20 ENSMUST00000110372.9
ENSMUST00000130563.2
acyl-CoA synthetase long-chain family member 1
chr5_-_143211632 0.20 ENSMUST00000085733.9
speedy/RINGO cell cycle regulator family, member E4A
chrX_-_72334121 0.19 ENSMUST00000088450.4
X-linked lymphocyte-regulated 5C
chr15_+_81350842 0.18 ENSMUST00000230062.2
ring-box 1
chr1_+_85577709 0.17 ENSMUST00000155094.8
ENSMUST00000054279.15
ENSMUST00000147552.8
ENSMUST00000153574.8
ENSMUST00000150967.8
nuclear antigen Sp100
chr8_-_3798922 0.17 ENSMUST00000208960.2
ENSMUST00000207979.2
CD209a antigen
chr14_+_26414422 0.17 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr3_+_96604415 0.17 ENSMUST00000107077.4
protein inhibitor of activated STAT 3
chr17_-_3746536 0.17 ENSMUST00000115800.2
NADPH oxidase 3
chrX_+_146548987 0.16 ENSMUST00000112814.8
predicted gene 15128
chrX_+_147880948 0.16 ENSMUST00000177554.2
ovary testis transcribed
chr11_+_49213569 0.16 ENSMUST00000215671.2
olfactory receptor 1391
chr19_-_45731312 0.16 ENSMUST00000026241.12
ENSMUST00000026240.14
ENSMUST00000111928.8
fibroblast growth factor 8
chr9_-_71803354 0.13 ENSMUST00000184448.8
transcription factor 12
chr15_+_68800261 0.12 ENSMUST00000022954.7
KH domain containing, RNA binding, signal transduction associated 3
chr10_-_4338032 0.11 ENSMUST00000100078.10
zinc finger and BTB domain containing 2
chr5_-_137531463 0.11 ENSMUST00000170293.8
guanine nucleotide binding protein (G protein), beta 2
chr3_-_64317478 0.10 ENSMUST00000170280.3
vomeronasal 2, receptor 4
chrX_+_36739065 0.10 ENSMUST00000089075.6
reproductive homeobox 4E
chr6_-_91784405 0.09 ENSMUST00000162300.8
glutamate receptor interacting protein 2
chr1_-_138547403 0.09 ENSMUST00000027642.5
ENSMUST00000186017.7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr2_+_88217406 0.08 ENSMUST00000214040.3
olfactory receptor 1178
chr1_+_173986288 0.07 ENSMUST00000068403.4
olfactory receptor 420
chr16_-_92622659 0.07 ENSMUST00000186296.2
runt related transcription factor 1
chr12_+_38830812 0.06 ENSMUST00000160856.8
ets variant 1
chr12_+_38831093 0.05 ENSMUST00000161513.9
ets variant 1
chr7_-_81216687 0.05 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr6_+_132739094 0.04 ENSMUST00000069268.3
taste receptor, type 2, member 102
chr12_+_17740831 0.03 ENSMUST00000071858.5
hippocalcin-like 1
chr11_+_98754434 0.03 ENSMUST00000142414.8
ENSMUST00000037480.9
WAS/WASL interacting protein family, member 2
chr5_-_137531413 0.02 ENSMUST00000168746.8
guanine nucleotide binding protein (G protein), beta 2
chr11_+_49138278 0.01 ENSMUST00000109194.2
mannoside acetylglucosaminyltransferase 1
chr12_+_87921198 0.01 ENSMUST00000110145.12
ENSMUST00000181843.2
ENSMUST00000180706.8
ENSMUST00000181394.8
ENSMUST00000181326.8
ENSMUST00000181300.2
predicted gene 2042

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9 2.6 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.8 4.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.6 1.9 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 1.6 GO:0051878 lateral element assembly(GO:0051878)
0.4 1.3 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 5.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 5.1 GO:0070842 aggresome assembly(GO:0070842)
0.4 1.9 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.4 2.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.6 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.3 3.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 0.6 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.3 1.6 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.3 3.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.2 1.4 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 1.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 7.0 GO:0097320 membrane tubulation(GO:0097320)
0.2 1.3 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.2 1.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.7 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.2 1.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.2 3.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 6.8 GO:0001562 response to protozoan(GO:0001562)
0.1 0.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 3.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 2.2 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.5 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.6 GO:0009992 cellular water homeostasis(GO:0009992)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.8 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.5 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 1.1 GO:0007614 short-term memory(GO:0007614)
0.0 1.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 2.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 2.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 2.0 GO:0045576 mast cell activation(GO:0045576)
0.0 0.8 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336) positive regulation of progesterone secretion(GO:2000872)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 2.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 2.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 4.5 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.3 GO:0044317 rod spherule(GO:0044317)
0.3 1.6 GO:0000802 transverse filament(GO:0000802)
0.3 1.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 7.0 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.3 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.9 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 4.1 GO:0097440 apical dendrite(GO:0097440)
0.1 2.0 GO:0044292 dendrite terminus(GO:0044292)
0.1 2.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 4.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.2 GO:0005884 actin filament(GO:0005884)
0.0 7.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 4.4 GO:0030017 sarcomere(GO:0030017)
0.0 0.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 1.4 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 2.6 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.8 GO:0031705 bombesin receptor binding(GO:0031705)
0.2 0.7 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.2 1.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 1.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 5.1 GO:0003680 AT DNA binding(GO:0003680)
0.2 3.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 3.0 GO:0005542 folic acid binding(GO:0005542)
0.1 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 4.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 2.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 1.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 4.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 7.0 GO:0005543 phospholipid binding(GO:0005543)
0.0 3.2 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 3.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 8.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling