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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx2-5

Z-value: 0.63

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Transcription factors associated with Nkx2-5

Gene Symbol Gene ID Gene Info
Nkx2-5
ENSMUSG00000015579.6 Nkx2-5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-5mm39_v1_chr17_-_27060539_270605650.132.8e-01Click!

Activity profile of Nkx2-5 motif

Sorted Z-values of Nkx2-5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_40853734 6.73 ENSMUST00000022314.10
ENSMUST00000170719.2
Sftpa1
surfactant associated protein A1
chr6_+_30639217 5.29 ENSMUST00000031806.10
Cpa1
carboxypeptidase A1, pancreatic
chr6_+_41279199 4.93 ENSMUST00000031913.5
Try4
trypsin 4
chr6_+_72281587 4.53 ENSMUST00000183018.8
ENSMUST00000182014.10
Sftpb
surfactant associated protein B
chr4_-_137137088 2.99 ENSMUST00000024200.7
Cela3a
chymotrypsin-like elastase family, member 3A
chr6_+_30541581 2.93 ENSMUST00000096066.5
Cpa2
carboxypeptidase A2, pancreatic
chr12_-_115611981 2.35 ENSMUST00000103540.3
ENSMUST00000199266.2
Ighv8-12
immunoglobulin heavy variable V8-12
chr12_-_114117264 2.31 ENSMUST00000103461.5
Ighv7-3
immunoglobulin heavy variable 7-3
chr12_-_113958518 2.26 ENSMUST00000103467.2
Ighv14-2
immunoglobulin heavy variable 14-2
chr12_-_114286421 2.13 ENSMUST00000103483.3
Ighv3-8
immunoglobulin heavy variable V3-8
chr15_-_82108531 1.81 ENSMUST00000109535.3
ENSMUST00000089161.10
Tnfrsf13c
tumor necrosis factor receptor superfamily, member 13c
chr1_-_170755136 1.69 ENSMUST00000046322.14
ENSMUST00000159171.2
Fcrla
Fc receptor-like A
chr1_-_170755109 1.61 ENSMUST00000162136.2
ENSMUST00000162887.2
Fcrla
Fc receptor-like A
chr6_-_136899167 1.52 ENSMUST00000032343.7
Erp27
endoplasmic reticulum protein 27
chr4_+_119494901 1.49 ENSMUST00000024015.3
Guca2a
guanylate cyclase activator 2a (guanylin)
chr12_-_115299134 1.45 ENSMUST00000195359.6
ENSMUST00000103530.3
Ighv1-59
immunoglobulin heavy variable V1-59
chr6_+_127554931 1.29 ENSMUST00000071563.5
Cracr2a
calcium release activated channel regulator 2A
chr14_+_51366306 1.14 ENSMUST00000226210.2
Rnase6
ribonuclease, RNase A family, 6
chr14_+_51366512 1.13 ENSMUST00000095923.4
Rnase6
ribonuclease, RNase A family, 6
chr9_+_123635529 1.11 ENSMUST00000049810.9
Cxcr6
chemokine (C-X-C motif) receptor 6
chr9_+_123635556 1.05 ENSMUST00000216072.2
Cxcr6
chemokine (C-X-C motif) receptor 6
chr3_+_3699205 0.98 ENSMUST00000108394.3
Hnf4g
hepatocyte nuclear factor 4, gamma
chr6_-_41535322 0.87 ENSMUST00000193003.2
Trbv31
T cell receptor beta, variable 31
chr5_+_28370687 0.76 ENSMUST00000036177.9
En2
engrailed 2
chr11_+_32483290 0.69 ENSMUST00000102821.4
Stk10
serine/threonine kinase 10
chr3_-_69767208 0.68 ENSMUST00000171529.4
ENSMUST00000051239.13
Sptssb
serine palmitoyltransferase, small subunit B
chrX_-_140508177 0.64 ENSMUST00000067841.8
Irs4
insulin receptor substrate 4
chr14_+_53743184 0.62 ENSMUST00000103583.5
Trav10
T cell receptor alpha variable 10
chr12_-_114186874 0.61 ENSMUST00000103477.4
ENSMUST00000192499.3
Ighv7-4
immunoglobulin heavy variable 7-4
chr11_+_87457479 0.60 ENSMUST00000239011.2
Septin4
septin 4
chr1_+_172168764 0.53 ENSMUST00000056136.4
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr14_+_53698556 0.48 ENSMUST00000181728.3
Trav7-4
T cell receptor alpha variable 7-4
chr5_+_16758777 0.48 ENSMUST00000030683.8
Hgf
hepatocyte growth factor
chr15_-_5273659 0.46 ENSMUST00000047379.15
Ptger4
prostaglandin E receptor 4 (subtype EP4)
chr11_+_64326141 0.46 ENSMUST00000058652.6
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr15_-_5273645 0.45 ENSMUST00000120563.2
Ptger4
prostaglandin E receptor 4 (subtype EP4)
chr17_+_27152276 0.43 ENSMUST00000237412.2
Phf1
PHD finger protein 1
chr19_+_53131187 0.41 ENSMUST00000050096.15
ENSMUST00000237832.2
Add3
adducin 3 (gamma)
chr11_+_67061908 0.41 ENSMUST00000018641.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr15_+_66542598 0.40 ENSMUST00000065916.14
Tg
thyroglobulin
chr4_-_45532470 0.40 ENSMUST00000147448.2
Shb
src homology 2 domain-containing transforming protein B
chr14_-_8798841 0.40 ENSMUST00000061045.3
Sntn
sentan, cilia apical structure protein
chr9_-_53447908 0.39 ENSMUST00000150244.2
Atm
ataxia telangiectasia mutated
chr11_-_78441584 0.39 ENSMUST00000103242.5
Tmem97
transmembrane protein 97
chr10_-_116732813 0.39 ENSMUST00000048229.9
Myrfl
myelin regulatory factor-like
chr11_+_67061837 0.39 ENSMUST00000170159.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr12_+_103281188 0.38 ENSMUST00000189885.2
ENSMUST00000179363.2
Fam181a
family with sequence similarity 181, member A
chr7_-_97794679 0.38 ENSMUST00000098281.4
Omp
olfactory marker protein
chr3_-_49711765 0.37 ENSMUST00000035931.13
Pcdh18
protocadherin 18
chr6_-_23650205 0.36 ENSMUST00000115354.2
Rnf133
ring finger protein 133
chr16_+_43993599 0.36 ENSMUST00000119746.8
ENSMUST00000088356.10
ENSMUST00000169582.3
Usf3
upstream transcription factor family member 3
chr6_-_23650297 0.35 ENSMUST00000063548.4
Rnf133
ring finger protein 133
chr5_+_16758897 0.33 ENSMUST00000196645.2
Hgf
hepatocyte growth factor
chr6_-_41535292 0.33 ENSMUST00000103300.3
Trbv31
T cell receptor beta, variable 31
chr8_+_114369838 0.32 ENSMUST00000095173.3
ENSMUST00000034219.12
ENSMUST00000212269.2
Syce1l
synaptonemal complex central element protein 1 like
chr14_+_80237691 0.31 ENSMUST00000228749.2
ENSMUST00000088735.4
Olfm4
olfactomedin 4
chr8_-_33374282 0.31 ENSMUST00000209107.4
ENSMUST00000209022.3
Nrg1
neuregulin 1
chr14_-_78326435 0.30 ENSMUST00000118785.3
ENSMUST00000066437.5
Fam216b
family with sequence similarity 216, member B
chr5_-_124465875 0.28 ENSMUST00000184951.8
Mphosph9
M-phase phosphoprotein 9
chr13_-_64645606 0.28 ENSMUST00000180282.2
Fam240b
family with sequence similarity 240 member B
chr10_+_60235628 0.27 ENSMUST00000218974.2
Gm17455
predicted gene, 17455
chr12_-_114909863 0.26 ENSMUST00000103517.2
ENSMUST00000195417.2
Ighv1-43
immunoglobulin heavy variable V1-43
chr9_+_53212871 0.26 ENSMUST00000051014.2
Exph5
exophilin 5
chr1_-_163552693 0.26 ENSMUST00000159679.8
Mettl11b
methyltransferase like 11B
chr3_-_153430741 0.26 ENSMUST00000064460.7
ENSMUST00000200397.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr8_+_125519751 0.26 ENSMUST00000041106.9
ENSMUST00000167588.9
Trim67
tripartite motif-containing 67
chr10_-_60667161 0.25 ENSMUST00000218637.2
Unc5b
unc-5 netrin receptor B
chr4_-_87724533 0.24 ENSMUST00000126353.8
ENSMUST00000149357.8
Mllt3
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr15_+_101071948 0.23 ENSMUST00000000544.12
Acvr1b
activin A receptor, type 1B
chr11_+_101877876 0.23 ENSMUST00000010985.8
Cfap97d1
CFAP97 domain containing 1
chr7_+_28869770 0.22 ENSMUST00000033886.8
ENSMUST00000209019.2
ENSMUST00000208330.2
Ggn
gametogenetin
chr11_-_96868483 0.22 ENSMUST00000107624.8
Sp2
Sp2 transcription factor
chr5_-_124465946 0.21 ENSMUST00000031344.13
Mphosph9
M-phase phosphoprotein 9
chr7_-_83304698 0.21 ENSMUST00000145610.8
Il16
interleukin 16
chr14_-_60488894 0.21 ENSMUST00000225111.2
Gm49336
predicted gene, 49336
chr7_-_126496534 0.21 ENSMUST00000120007.8
Tmem219
transmembrane protein 219
chr4_-_19122526 0.20 ENSMUST00000137780.2
Cnbd1
cyclic nucleotide binding domain containing 1
chr14_+_53328803 0.20 ENSMUST00000103609.2
Trav7n-4
T cell receptor alpha variable 7N-4
chr13_+_111391544 0.18 ENSMUST00000054716.4
Actbl2
actin, beta-like 2
chr4_-_87724512 0.18 ENSMUST00000148059.2
Mllt3
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr5_-_82271183 0.17 ENSMUST00000186079.2
ENSMUST00000185607.2
1700031L13Rik
RIKEN cDNA 1700031L13 gene
chr10_+_36383008 0.17 ENSMUST00000168572.8
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr14_+_53007210 0.17 ENSMUST00000178768.4
Trav7d-4
T cell receptor alpha variable 7D-4
chrX_+_12937714 0.17 ENSMUST00000169594.9
ENSMUST00000089302.11
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr15_+_76235503 0.16 ENSMUST00000023212.15
ENSMUST00000160172.8
Maf1
MAF1 homolog, negative regulator of RNA polymerase III
chr7_+_28869629 0.16 ENSMUST00000098609.4
Ggn
gametogenetin
chr18_+_49965689 0.16 ENSMUST00000180611.8
Dmxl1
Dmx-like 1
chr16_-_89368059 0.15 ENSMUST00000171542.2
Krtap11-1
keratin associated protein 11-1
chr1_-_133589020 0.15 ENSMUST00000193504.6
ENSMUST00000195067.2
ENSMUST00000191896.6
ENSMUST00000194668.6
ENSMUST00000195424.6
ENSMUST00000179598.4
ENSMUST00000027736.13
Zc3h11a
Gm38394
Zc3h11a
zinc finger CCCH type containing 11A
predicted gene, 38394
zinc finger CCCH type containing 11A
chrX_+_41149264 0.15 ENSMUST00000224454.2
Xiap
X-linked inhibitor of apoptosis
chr9_-_119852624 0.14 ENSMUST00000111635.4
Xirp1
xin actin-binding repeat containing 1
chr14_+_53073315 0.14 ENSMUST00000197128.2
Trav7d-5
T cell receptor alpha variable 7D-5
chr6_+_42263644 0.14 ENSMUST00000163936.8
Clcn1
chloride channel, voltage-sensitive 1
chr11_+_87457544 0.14 ENSMUST00000060360.7
Septin4
septin 4
chr16_+_33504908 0.14 ENSMUST00000126532.2
Heg1
heart development protein with EGF-like domains 1
chr14_-_60488922 0.13 ENSMUST00000225311.2
ENSMUST00000041905.8
Gm49336
predicted gene, 49336
chr6_-_52222776 0.13 ENSMUST00000048026.10
Hoxa11
homeobox A11
chr11_+_23234644 0.13 ENSMUST00000150750.3
Xpo1
exportin 1
chr6_-_90013823 0.13 ENSMUST00000073415.2
Vmn1r48
vomeronasal 1 receptor 48
chr11_+_68858942 0.12 ENSMUST00000102606.10
ENSMUST00000018884.6
Slc25a35
solute carrier family 25, member 35
chrX_-_91164377 0.12 ENSMUST00000088137.3
Mageb18
MAGE family member B18
chr11_+_49334680 0.12 ENSMUST00000055584.2
Olfr1388
olfactory receptor 1388
chr11_+_49321254 0.11 ENSMUST00000203369.2
Olfr1389
olfactory receptor 1389
chrX_-_154123743 0.11 ENSMUST00000130349.3
Prdx4
peroxiredoxin 4
chr2_-_120439764 0.10 ENSMUST00000102496.8
Lrrc57
leucine rich repeat containing 57
chr10_+_60236532 0.10 ENSMUST00000218360.2
Gm17455
predicted gene, 17455
chr6_-_5193816 0.10 ENSMUST00000002663.12
Pon1
paraoxonase 1
chr5_-_71815218 0.10 ENSMUST00000198138.2
Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chrX_-_7765096 0.09 ENSMUST00000154552.2
Pqbp1
polyglutamine binding protein 1
chr2_-_73316809 0.09 ENSMUST00000141264.8
Wipf1
WAS/WASL interacting protein family, member 1
chr6_-_115830249 0.09 ENSMUST00000122816.3
Mbd4
methyl-CpG binding domain protein 4
chr6_-_28421678 0.09 ENSMUST00000090511.4
Gcc1
golgi coiled coil 1
chr8_-_46747629 0.09 ENSMUST00000058636.9
Helt
helt bHLH transcription factor
chr7_-_134100659 0.08 ENSMUST00000238294.2
D7Ertd443e
DNA segment, Chr 7, ERATO Doi 443, expressed
chr15_-_10470575 0.08 ENSMUST00000136591.8
Dnajc21
DnaJ heat shock protein family (Hsp40) member C21
chr9_-_50657800 0.07 ENSMUST00000239417.2
ENSMUST00000034564.4
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr11_+_115865535 0.07 ENSMUST00000021107.14
ENSMUST00000169928.8
ENSMUST00000106461.8
Itgb4
integrin beta 4
chr16_-_56748424 0.07 ENSMUST00000210579.2
Lnp1
leukemia NUP98 fusion partner 1
chr15_-_76419131 0.07 ENSMUST00000230604.2
Tmem249
transmembrane protein 249
chr2_+_89642395 0.06 ENSMUST00000214508.2
Olfr1255
olfactory receptor 1255
chr11_+_73125118 0.06 ENSMUST00000102526.9
Trpv1
transient receptor potential cation channel, subfamily V, member 1
chr17_-_56916771 0.05 ENSMUST00000052832.6
Micos13
mitochondrial contact site and cristae organizing system subunit 13
chr10_+_79824418 0.05 ENSMUST00000004784.11
ENSMUST00000105374.2
Cnn2
calponin 2
chr10_+_22520910 0.05 ENSMUST00000042261.5
Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr3_-_129597679 0.05 ENSMUST00000185462.7
ENSMUST00000179187.2
Lrit3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr5_-_8417982 0.04 ENSMUST00000088761.11
ENSMUST00000115386.8
ENSMUST00000050166.14
ENSMUST00000046838.14
ENSMUST00000115388.9
ENSMUST00000088744.12
ENSMUST00000115385.2
Adam22
a disintegrin and metallopeptidase domain 22
chrX_-_74460168 0.04 ENSMUST00000033543.14
ENSMUST00000149863.3
ENSMUST00000114081.2
Cmc4
Mtcp1
C-x(9)-C motif containing 4
mature T cell proliferation 1
chr12_-_115531211 0.04 ENSMUST00000103536.4
Ighv8-11
immunoglobulin heavy variable V8-11
chr6_+_136530970 0.03 ENSMUST00000189535.2
Atf7ip
activating transcription factor 7 interacting protein
chr7_-_4909515 0.03 ENSMUST00000210663.2
Gm36210
predicted gene, 36210
chr9_+_7347369 0.03 ENSMUST00000005950.12
ENSMUST00000065079.6
Mmp12
matrix metallopeptidase 12
chr16_+_44764028 0.03 ENSMUST00000114613.9
ENSMUST00000114612.8
ENSMUST00000077178.13
ENSMUST00000048479.14
ENSMUST00000114611.10
Cd200r3
CD200 receptor 3
chr6_+_92846338 0.03 ENSMUST00000113434.2
Gm15737
predicted gene 15737
chr11_-_99907030 0.03 ENSMUST00000018399.3
Krt33a
keratin 33A
chrX_-_164110372 0.02 ENSMUST00000058787.9
Glra2
glycine receptor, alpha 2 subunit
chr2_-_111251294 0.02 ENSMUST00000099617.2
Olfr1286
olfactory receptor 1286
chr3_-_129834788 0.01 ENSMUST00000168644.3
Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr16_+_44764099 0.00 ENSMUST00000114622.10
ENSMUST00000166731.2
Cd200r3
CD200 receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.7 GO:0008228 opsonization(GO:0008228)
0.3 0.9 GO:1904464 negative regulation of integrin activation(GO:0033624) regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417)
0.3 1.8 GO:0031296 B cell costimulation(GO:0031296)
0.2 1.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.5 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 0.4 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.7 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 8.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 4.5 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.8 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0003017 lymph circulation(GO:0003017)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 2.3 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.4 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 3.7 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0051324 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 2.3 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 6.7 GO:0005771 multivesicular body(GO:0005771)
0.1 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.7 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 8.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.3 8.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.5 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 8.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 8.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 2.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 3.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 4.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 2.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling