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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx3-1

Z-value: 1.27

Motif logo

Transcription factors associated with Nkx3-1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022061.9 Nkx3-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-1mm39_v1_chr14_+_69428087_69428140-0.056.8e-01Click!

Activity profile of Nkx3-1 motif

Sorted Z-values of Nkx3-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_58748132 10.49 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr3_-_113325938 7.34 ENSMUST00000132353.2
amylase 2a1
chr4_-_137157824 7.34 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr6_-_41012435 6.46 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr3_-_113198765 6.16 ENSMUST00000179568.3
amylase 2a4
chr3_-_113231368 5.77 ENSMUST00000179314.3
amylase 2a3
chr3_-_113263974 5.68 ENSMUST00000098667.5
amylase 2a2
chr6_+_78402956 5.32 ENSMUST00000079926.6
regenerating islet-derived 1
chr3_-_113166153 5.04 ENSMUST00000098673.5
amylase 2a5
chr8_+_114860375 4.57 ENSMUST00000147605.8
ENSMUST00000134593.2
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_+_46984016 4.55 ENSMUST00000152423.2
acyl-CoA synthetase long-chain family member 1
chr8_+_114860297 4.46 ENSMUST00000073521.12
ENSMUST00000066514.13
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_-_92659644 4.21 ENSMUST00000029527.6
late cornified envelope 1G
chr8_+_114860342 4.17 ENSMUST00000109109.8
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_+_146276147 4.08 ENSMUST00000199489.5
urate oxidase
chr1_+_139429430 3.97 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr10_-_59277570 3.89 ENSMUST00000009798.5
oncoprotein induced transcript 3
chr4_-_108075119 3.77 ENSMUST00000223127.2
ENSMUST00000043793.7
ENSMUST00000106690.9
zyg-11 family member A, cell cycle regulator
chr11_-_58504307 3.72 ENSMUST00000048801.8
LY6/PLAUR domain containing 8 like
chr14_-_21798678 3.69 ENSMUST00000075040.9
dual specificity phosphatase 13
chr15_-_96918203 3.69 ENSMUST00000166223.2
solute carrier family 38, member 4
chr11_-_21320452 3.56 ENSMUST00000102875.11
UDP-glucose pyrophosphorylase 2
chr4_-_137137088 3.48 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr12_+_8062331 3.43 ENSMUST00000171239.2
apolipoprotein B
chr1_-_190897012 3.43 ENSMUST00000171798.2
family with sequence similarity 71, member A
chr6_-_83504471 3.25 ENSMUST00000141904.8
actin, gamma 2, smooth muscle, enteric
chr2_-_84605764 3.24 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84605732 3.17 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_-_83504756 3.15 ENSMUST00000152029.2
actin, gamma 2, smooth muscle, enteric
chr5_-_145521533 3.10 ENSMUST00000075837.8
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr14_-_21798694 3.04 ENSMUST00000183943.2
dual specificity phosphatase 13
chr11_-_121410152 2.85 ENSMUST00000092298.6
zinc finger protein 750
chr5_-_145816774 2.76 ENSMUST00000035918.8
cytochrome P450, family 3, subfamily a, polypeptide 11
chr4_-_115353326 2.72 ENSMUST00000030487.3
cytochrome P450, family 4, subfamily a, polypeptide 14
chrX_+_149330371 2.71 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chrX_+_163052367 2.65 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr3_-_92686198 2.64 ENSMUST00000090866.2
late cornified envelope 1I
chr5_-_145742672 2.61 ENSMUST00000067479.6
cytochrome P450, family 3, subfamily a, polypeptide 44
chr5_-_21629661 2.59 ENSMUST00000115245.8
ENSMUST00000030552.7
coiled-coil domain containing 146
chr6_+_54016543 2.54 ENSMUST00000046856.14
chimerin 2
chr13_-_41981893 2.51 ENSMUST00000137905.2
androgen dependent TFPI regulating protein
chr3_+_57332735 2.47 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr5_-_145406533 2.46 ENSMUST00000031633.5
cytochrome P450, family 3, subfamily a, polypeptide 16
chr1_+_157334347 2.39 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr3_+_93184854 2.38 ENSMUST00000180308.3
filaggrin
chr5_-_145656934 2.37 ENSMUST00000094111.6
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr1_+_157334298 2.36 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr13_-_41981812 2.27 ENSMUST00000223337.2
ENSMUST00000221691.2
androgen dependent TFPI regulating protein
chr19_-_10217968 2.27 ENSMUST00000189897.2
ENSMUST00000186056.7
ENSMUST00000088013.12
myelin regulatory factor
chr14_+_40853734 2.26 ENSMUST00000022314.10
ENSMUST00000170719.2
surfactant associated protein A1
chr9_+_78099229 2.18 ENSMUST00000034903.7
glutathione S-transferase, alpha 4
chr7_-_133203838 2.15 ENSMUST00000033275.4
testis expressed 36
chr2_+_79538124 2.12 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr18_+_43897354 2.11 ENSMUST00000187157.7
ENSMUST00000043803.13
ENSMUST00000189750.2
secretoglobin, family 3A, member 2
chr5_+_73071607 2.09 ENSMUST00000144843.8
SLAIN motif family, member 2
chr13_-_42000958 1.96 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr18_-_12995681 1.93 ENSMUST00000121808.8
ENSMUST00000118313.8
oxysterol binding protein-like 1A
chr12_+_101370932 1.89 ENSMUST00000055156.5
cation channel sperm associated auxiliary subunit beta
chr1_-_107206091 1.78 ENSMUST00000166100.2
ENSMUST00000027565.5
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
serine (or cysteine) peptidase inhibitor, clade B, member 3C
chr9_-_103099262 1.75 ENSMUST00000170904.2
transferrin
chr14_+_64331130 1.74 ENSMUST00000224112.2
ENSMUST00000165710.2
ENSMUST00000170709.2
protease, serine 51
chr2_-_52225763 1.74 ENSMUST00000238288.2
ENSMUST00000238749.2
nebulin
chr6_-_88604404 1.71 ENSMUST00000120933.5
kelch repeat and BTB (POZ) domain containing 12
chr3_-_54962899 1.71 ENSMUST00000199144.5
cyclin A1
chr3_-_54962922 1.69 ENSMUST00000197238.5
cyclin A1
chr15_+_102058936 1.67 ENSMUST00000023806.14
sterol O-acyltransferase 2
chr19_-_8382424 1.61 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr12_+_17316546 1.61 ENSMUST00000057288.7
ENSMUST00000239402.2
protein disulfide isomerase associated 6
chrY_+_12273932 1.58 ENSMUST00000187922.2
predicted gene 29554
chr18_+_57666852 1.58 ENSMUST00000079738.10
ENSMUST00000135806.8
ENSMUST00000127130.9
coiled-coil domain containing 192
chr7_-_103799746 1.55 ENSMUST00000059121.5
ubiquilin-like
chr8_-_41494890 1.54 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr11_-_61269131 1.53 ENSMUST00000148671.2
solute carrier family 47, member 1
chr17_-_57289121 1.52 ENSMUST00000056113.5
alkaline ceramidase 1
chr9_+_103917821 1.51 ENSMUST00000216593.2
ENSMUST00000147249.3
nephronophthisis 3 (adolescent)
predicted gene 28305
chr5_-_24732200 1.51 ENSMUST00000088311.6
gastrulation brain homeobox 1
chrY_+_57195716 1.50 ENSMUST00000189109.7
ENSMUST00000191355.7
ENSMUST00000190292.2
Sycp3 like Y-linked
chr2_+_22959223 1.50 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr5_-_134776101 1.48 ENSMUST00000015138.13
elastin
chr10_+_97442727 1.47 ENSMUST00000105286.4
keratocan
chr1_+_170983081 1.47 ENSMUST00000111334.2
myelin protein zero
chr9_-_40873629 1.45 ENSMUST00000160120.2
junctional cadherin complex regulator
chrY_+_65386218 1.42 ENSMUST00000190282.7
ENSMUST00000185550.7
predicted gene, 20736
chrX_+_14077387 1.39 ENSMUST00000105137.4
H2A histone family member L1N
chrX_-_117390434 1.39 ENSMUST00000073857.6
TGFB-induced factor homeobox 2-like, X-linked 1
chr1_+_106908709 1.38 ENSMUST00000027564.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr4_+_134124691 1.38 ENSMUST00000105870.8
platelet-activating factor acetylhydrolase 2
chrY_-_1459771 1.35 ENSMUST00000091188.7
ubiquitin specific peptidase 9, Y chromosome
chr9_+_106325860 1.33 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr10_-_128047658 1.32 ENSMUST00000061995.10
SPRY domain containing 4
chrY_-_68306157 1.31 ENSMUST00000189084.7
ENSMUST00000189422.7
predicted gene, 20937
chr5_-_86893645 1.30 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr17_+_29487881 1.30 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chrX_+_156481906 1.26 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr3_+_62327089 1.26 ENSMUST00000161057.2
Rho guanine nucleotide exchange factor (GEF) 26
chr1_-_130380153 1.24 ENSMUST00000140400.2
CD55 molecule, decay accelerating factor for complement
chrY_+_14400710 1.23 ENSMUST00000192683.2
predicted gene, 30737
chrY_+_81469276 1.23 ENSMUST00000187135.2
predicted gene, 20911
chrY_+_19113007 1.23 ENSMUST00000194086.2
predicted gene, 35134
chrY_+_71480718 1.21 ENSMUST00000188958.2
predicted gene, 20869
chrY_+_87128072 1.21 ENSMUST00000189543.7
predicted gene, 21477
chrY_-_35087178 1.21 ENSMUST00000186996.7
predicted gene, 20855
chrY_+_88064584 1.21 ENSMUST00000187146.2
predicted gene 28102
chrY_+_7722941 1.21 ENSMUST00000189007.2
predicted gene 28576
chrY_+_78224262 1.20 ENSMUST00000185575.2
predicted gene 29564
chrY_+_80145048 1.20 ENSMUST00000187433.7
predicted gene, 21760
chrY_+_61655274 1.20 ENSMUST00000189455.2
predicted gene, 21497
chrY_-_40272248 1.20 ENSMUST00000191443.7
predicted gene, 21865
chrY_+_48861106 1.20 ENSMUST00000185924.2
predicted gene 28553
chrY_+_7253787 1.20 ENSMUST00000186194.2
predicted gene 28998
chrY_+_76772869 1.20 ENSMUST00000189238.2
predicted gene, 21173
chrY_-_68843997 1.20 ENSMUST00000191123.2
predicted gene, 20817
chrY_-_35876871 1.20 ENSMUST00000188585.7
predicted gene, 20896
chrY_+_80938264 1.20 ENSMUST00000185340.2
predicted gene 28897
chrY_+_83042216 1.20 ENSMUST00000187165.2
predicted gene 28827
chrX_+_133088238 1.19 ENSMUST00000064476.5
ADP-ribosylation factor-like 13A
chrY_+_74481800 1.19 ENSMUST00000189924.2
predicted gene 29110
chrY_-_22046833 1.19 ENSMUST00000192521.2
predicted gene, 31571
chrY_+_86073041 1.18 ENSMUST00000188754.2
predicted gene, 20820
chrY_+_87562235 1.18 ENSMUST00000186493.2
predicted gene, 20906
chrX_+_117336912 1.18 ENSMUST00000072518.8
TGFB-induced factor homeobox 2-like, X-linked 2
chr10_-_129751466 1.18 ENSMUST00000213438.2
olfactory receptor 816
chrY_+_53840528 1.18 ENSMUST00000186578.2
predicted gene, 20929
chrY_+_82236496 1.18 ENSMUST00000185636.2
predicted gene, 21317
chrY_-_22856736 1.18 ENSMUST00000192892.2
predicted gene, 21366
chrY_+_84757954 1.18 ENSMUST00000186110.2
predicted gene, 21409
chrY_-_36690635 1.18 ENSMUST00000185565.2
predicted gene, 20835
chrY_-_37214948 1.18 ENSMUST00000190782.2
predicted gene, 20905
chrY_+_52776619 1.18 ENSMUST00000191553.7
predicted gene, 21258
chrY_+_75726591 1.18 ENSMUST00000188672.2
predicted gene, 20850
chrY_-_20993657 1.17 ENSMUST00000191675.2
predicted gene, 29866
chrY_+_49567735 1.17 ENSMUST00000189354.7
predicted gene, 21209
chrY_+_62199394 1.17 ENSMUST00000186938.7
predicted gene, 21518
chrY_+_63236955 1.17 ENSMUST00000187768.2
predicted gene, 21627
chrY_+_79330834 1.17 ENSMUST00000185338.7
predicted gene, 20916
chrY_+_71703312 1.17 ENSMUST00000189315.2
predicted gene, 20870
chrY_+_50604830 1.17 ENSMUST00000185245.2
predicted gene, 20883
chrY_+_51121799 1.17 ENSMUST00000185327.7
predicted gene, 21117
chrY_+_55728335 1.17 ENSMUST00000185713.7
predicted gene, 21858
chrY_-_72258387 1.17 ENSMUST00000191305.7
predicted gene, 20843
chrY_+_73680584 1.16 ENSMUST00000189346.2
predicted gene, 20903
chrY_+_57714225 1.16 ENSMUST00000190573.2
predicted gene 28961
chrY_+_77704077 1.16 ENSMUST00000190551.7
predicted gene, 21650
chrY_+_84108548 1.16 ENSMUST00000185776.7
predicted gene, 21095
chrY_+_51848699 1.15 ENSMUST00000187477.2
predicted gene, 20920
chrY_+_64481794 1.15 ENSMUST00000186004.2
predicted gene, 20908
chrY_+_55210299 1.14 ENSMUST00000187293.7
predicted gene, 20931
chrY_+_75207125 1.14 ENSMUST00000190173.2
predicted gene, 20814
chrY_+_70453151 1.13 ENSMUST00000186890.7
predicted gene, 20888
chrY_+_8257907 1.12 ENSMUST00000186739.2
predicted gene, 20824
chrX_+_61511597 1.12 ENSMUST00000033537.2
RIKEN cDNA 4931400O07 gene
chr9_+_40785277 1.12 ENSMUST00000067375.5
brain specific homeobox
chr16_-_37681508 1.10 ENSMUST00000205931.2
predicted gene, 36028
chrY_+_89064075 1.10 ENSMUST00000186443.2
predicted gene, 21294
chrY_-_28226857 1.09 ENSMUST00000188864.2
predicted gene, 20894
chr5_-_72716942 1.09 ENSMUST00000074948.5
ENSMUST00000087216.12
nuclear transcription factor, X-box binding-like 1
chrX_+_110154017 1.09 ENSMUST00000210720.3
cylicin, basic protein of sperm head cytoskeleton 1
chrY_-_26732144 1.09 ENSMUST00000189518.2
predicted gene, 20890
chrY_-_27477265 1.09 ENSMUST00000188744.2
predicted gene, 21488
chrY_+_6583546 1.07 ENSMUST00000190026.2
predicted gene 28919
chrY_-_42537595 1.06 ENSMUST00000190453.2
predicted gene 29276
chr10_+_69055215 1.06 ENSMUST00000172261.3
Rho-related BTB domain containing 1
chrY_+_13494026 1.05 ENSMUST00000193306.2
predicted gene, 20773
chrY_-_38457583 1.05 ENSMUST00000185240.2
predicted gene, 20897
chrY_+_17874741 1.03 ENSMUST00000188928.3
ENSMUST00000177639.7
predicted gene, 20772
predicted gene, 20831
chrY_+_13252391 1.03 ENSMUST00000192749.2
ENSMUST00000178599.7
predicted gene, 21440
predicted gene, 21454
chr18_+_12732951 1.02 ENSMUST00000234255.2
ENSMUST00000169401.8
tetratricopeptide repeat domain 39C
chr18_+_44237577 1.01 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr7_+_12568647 1.00 ENSMUST00000004614.15
zinc finger protein 110
chr3_-_95595157 0.99 ENSMUST00000015994.4
ENSMUST00000148854.2
ENSMUST00000117782.8
ADAMTS-like 4
chrY_+_13042891 0.98 ENSMUST00000194687.2
predicted gene, 20807
chrY_-_10536042 0.97 ENSMUST00000187245.2
predicted gene, 20737
chrY_+_13376362 0.95 ENSMUST00000192204.2
predicted gene, 21454
chrY_+_18089116 0.95 ENSMUST00000186035.2
spermiogenesis specific transcript on the Y 1
chrY_+_40760259 0.95 ENSMUST00000190909.2
predicted gene, 20795
chrX_+_156482116 0.95 ENSMUST00000112521.8
small muscle protein, X-linked
chr1_-_173569301 0.94 ENSMUST00000042610.15
ENSMUST00000127730.2
interferon activated gene 207
chr3_+_14928561 0.93 ENSMUST00000029076.6
carbonic anhydrase 3
chrX_-_4194587 0.93 ENSMUST00000179325.2
BTB domain containing 35, family member 20
chr2_+_22959452 0.92 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chrY_+_17965160 0.92 ENSMUST00000194411.2
predicted gene, 20831
chrY_+_13161968 0.92 ENSMUST00000195626.2
predicted gene, 21425
chr9_+_39933648 0.90 ENSMUST00000059859.5
olfactory receptor 981
chr2_-_151510453 0.89 ENSMUST00000180195.8
ENSMUST00000096439.4
RAD21-like (S. pombe)
chr6_-_40521911 0.85 ENSMUST00000089490.3
olfactory receptor 461
chr9_-_20887967 0.85 ENSMUST00000214218.2
sphingosine-1-phosphate receptor 2
chr3_-_146391230 0.84 ENSMUST00000197989.2
ENSMUST00000125965.8
sterile alpha motif domain containing 13
chr2_+_22958179 0.83 ENSMUST00000227663.2
ENSMUST00000028121.15
ENSMUST00000227809.2
ENSMUST00000144088.2
acyl-Coenzyme A binding domain containing 5
chr18_-_84854841 0.81 ENSMUST00000236689.2
predicted gene, 17266
chr2_+_37029334 0.80 ENSMUST00000214905.2
ENSMUST00000217298.2
ENSMUST00000104995.3
olfactory receptor 364, pseudogene 1
chrX_+_163221035 0.80 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr14_+_51599213 0.77 ENSMUST00000162998.2
predicted gene 7247
chr17_+_35354172 0.76 ENSMUST00000172571.8
ENSMUST00000173491.8
BCL2-associated athanogene 6
chr17_-_15784582 0.75 ENSMUST00000147532.8
PR domain containing 9
chr7_+_103205286 0.73 ENSMUST00000214345.2
ENSMUST00000215673.2
olfactory receptor 615
chr3_+_90155479 0.73 ENSMUST00000015467.9
solute carrier family 39 (zinc transporter), member 1
chr4_-_156340713 0.73 ENSMUST00000219393.2
sterile alpha motif domain containing 11
chrX_-_74918122 0.72 ENSMUST00000033547.14
plastin 3 (T-isoform)
chr7_-_107857554 0.71 ENSMUST00000215173.2
olfactory receptor 488
chrX_-_74918709 0.71 ENSMUST00000114059.10
plastin 3 (T-isoform)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.2 GO:0034034 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
2.1 6.4 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.2 3.6 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.6 10.5 GO:0019374 galactolipid metabolic process(GO:0019374)
0.5 1.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.5 4.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 3.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.3 0.7 GO:0060300 regulation of cytokine activity(GO:0060300)
0.3 5.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 1.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.3 1.5 GO:0010446 response to alkaline pH(GO:0010446)
0.3 3.2 GO:0030242 pexophagy(GO:0030242)
0.3 4.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.3 2.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 1.4 GO:0032053 ciliary basal body organization(GO:0032053) cerebrospinal fluid secretion(GO:0033326)
0.2 1.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 1.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.2 1.7 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 2.3 GO:0008228 opsonization(GO:0008228)
0.2 1.9 GO:0015747 urate transport(GO:0015747)
0.2 3.7 GO:0046415 urate metabolic process(GO:0046415)
0.2 2.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 1.4 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.2 1.2 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.3 GO:0021828 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) neural crest cell migration involved in sympathetic nervous system development(GO:1903045) facioacoustic ganglion development(GO:1903375)
0.1 1.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.6 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.9 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 1.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 6.9 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 38.3 GO:0051321 meiotic cell cycle(GO:0051321)
0.1 2.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 2.1 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 3.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 10.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 0.6 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 3.8 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.9 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.5 GO:0007530 sex determination(GO:0007530)
0.0 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 1.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 1.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.0 1.3 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 3.6 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 1.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0034359 mature chylomicron(GO:0034359)
0.8 3.4 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.5 10.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 1.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.3 5.3 GO:0042588 zymogen granule(GO:0042588)
0.3 45.1 GO:0000800 lateral element(GO:0000800)
0.3 1.5 GO:0071953 elastic fiber(GO:0071953)
0.3 2.2 GO:0005927 muscle tendon junction(GO:0005927)
0.3 1.1 GO:0043159 acrosomal matrix(GO:0043159)
0.2 3.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 9.2 GO:0001533 cornified envelope(GO:0001533)
0.2 1.8 GO:0097433 dense body(GO:0097433)
0.1 1.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.9 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 25.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 2.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 11.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 13.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.2 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 22.7 GO:0004556 alpha-amylase activity(GO:0004556)
2.6 13.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.7 13.3 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.9 4.6 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.9 2.7 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.9 2.6 GO:0008127 quercetin 2,3-dioxygenase activity(GO:0008127)
0.7 10.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 3.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.4 2.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 2.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.3 4.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 2.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 3.4 GO:0035473 lipase binding(GO:0035473)
0.3 1.8 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 6.4 GO:0001848 complement binding(GO:0001848)
0.2 0.7 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.2 1.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 4.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.1 2.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 6.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 20.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.7 GO:0036122 BMP binding(GO:0036122)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 5.3 GO:0008083 growth factor activity(GO:0008083)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 20.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 4.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 6.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 3.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 9.6 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 6.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG